Optical imaging agents have been widely used for diagnosis and phototherapy.1,2 However,light−tissue interactions limit the imaging and therapeutic abilities of optical agents tosuperffcial or endoscopically accessibl...Optical imaging agents have been widely used for diagnosis and phototherapy.1,2 However,light−tissue interactions limit the imaging and therapeutic abilities of optical agents tosuperffcial or endoscopically accessible tissues.3,4 Afterglowagents,which can achieve highly sensitive detection of deeptissue biomarkers due to the elimination of tissue autoffuor-escence,have emerged to mitigate this issue.5 Unfortunately,thepotential application of photoinduced afterglow agents in deeptissues is limited due to the requirement of preirradiation beforeluminescence and the depth of light penetration.展开更多
文摘Optical imaging agents have been widely used for diagnosis and phototherapy.1,2 However,light−tissue interactions limit the imaging and therapeutic abilities of optical agents tosuperffcial or endoscopically accessible tissues.3,4 Afterglowagents,which can achieve highly sensitive detection of deeptissue biomarkers due to the elimination of tissue autoffuor-escence,have emerged to mitigate this issue.5 Unfortunately,thepotential application of photoinduced afterglow agents in deeptissues is limited due to the requirement of preirradiation beforeluminescence and the depth of light penetration.