Due to the dynamic nature and node mobility,assuring the security of Mobile Ad-hoc Networks(MANET)is one of the difficult and challenging tasks today.In MANET,the Intrusion Detection System(IDS)is crucial because it a...Due to the dynamic nature and node mobility,assuring the security of Mobile Ad-hoc Networks(MANET)is one of the difficult and challenging tasks today.In MANET,the Intrusion Detection System(IDS)is crucial because it aids in the identification and detection of malicious attacks that impair the network’s regular operation.Different machine learning and deep learning methodologies are used for this purpose in the conventional works to ensure increased security of MANET.However,it still has significant flaws,including increased algorithmic complexity,lower system performance,and a higher rate of misclassification.Therefore,the goal of this paper is to create an intelligent IDS framework for significantly enhancing MANET security through the use of deep learning models.Here,the min-max normalization model is applied to preprocess the given cyber-attack datasets for normalizing the attributes or fields,which increases the overall intrusion detection performance of classifier.Then,a novel Adaptive Marine Predator Optimization Algorithm(AOMA)is implemented to choose the optimal features for improving the speed and intrusion detection performance of classifier.Moreover,the Deep Supervise Learning Classification(DSLC)mechanism is utilized to predict and categorize the type of intrusion based on proper learning and training operations.During evaluation,the performance and results of the proposed AOMA-DSLC based IDS methodology is validated and compared using various performance measures and benchmarking datasets.展开更多
With an increasing number of services connected to the internet,including cloud computing and Internet of Things(IoT)systems,the prevention of cyberattacks has become more challenging due to the high dimensionality of...With an increasing number of services connected to the internet,including cloud computing and Internet of Things(IoT)systems,the prevention of cyberattacks has become more challenging due to the high dimensionality of the network traffic data and access points.Recently,researchers have suggested deep learning(DL)algorithms to define intrusion features through training empirical data and learning anomaly patterns of attacks.However,due to the high dynamics and imbalanced nature of the data,the existing DL classifiers are not completely effective at distinguishing between abnormal and normal behavior line connections for modern networks.Therefore,it is important to design a self-adaptive model for an intrusion detection system(IDS)to improve the detection of attacks.Consequently,in this paper,a novel hybrid weighted deep belief network(HW-DBN)algorithm is proposed for building an efficient and reliable IDS(DeepIoT.IDS)model to detect existing and novel cyberattacks.The HW-DBN algorithm integrates an improved Gaussian–Bernoulli restricted Boltzmann machine(Deep GB-RBM)feature learning operator with a weighted deep neural networks(WDNN)classifier.The CICIDS2017 dataset is selected to evaluate the DeepIoT.IDS model as it contains multiple types of attacks,complex data patterns,noise values,and imbalanced classes.We have compared the performance of the DeepIoT.IDS model with three recent models.The results show the DeepIoT.IDS model outperforms the three other models by achieving a higher detection accuracy of 99.38%and 99.99%for web attack and bot attack scenarios,respectively.Furthermore,it can detect the occurrence of low-frequency attacks that are undetectable by other models.展开更多
Coronavirus has infected more than 753 million people,ranging in severity from one person to another,where more than six million infected people died worldwide.Computer-aided diagnostic(CAD)with artificial intelligenc...Coronavirus has infected more than 753 million people,ranging in severity from one person to another,where more than six million infected people died worldwide.Computer-aided diagnostic(CAD)with artificial intelligence(AI)showed outstanding performance in effectively diagnosing this virus in real-time.Computed tomography is a complementary diagnostic tool to clarify the damage of COVID-19 in the lungs even before symptoms appear in patients.This paper conducts a systematic literature review of deep learning methods for classifying the segmentation of COVID-19 infection in the lungs.We used the methodology of systematic reviews and meta-analyses(PRISMA)flow method.This research aims to systematically analyze the supervised deep learning methods,open resource datasets,data augmentation methods,and loss functions used for various segment shapes of COVID-19 infection from computerized tomography(CT)chest images.We have selected 56 primary studies relevant to the topic of the paper.We have compared different aspects of the algorithms used to segment infected areas in the CT images.Limitations to deep learning in the segmentation of infected areas still need to be developed to predict smaller regions of infection at the beginning of their appearance.展开更多
Accurate prognosis prediction is essential for guiding cancer treatment and improving patient outcomes.While recent studies have demonstrated the potential of histopathological images in survival analysis,existing mod...Accurate prognosis prediction is essential for guiding cancer treatment and improving patient outcomes.While recent studies have demonstrated the potential of histopathological images in survival analysis,existing models are typically developed in a cancerspecific manner,lack extensive external validation,and often rely on molecular data that are not routinely available in clinical practice.To address these limitations,we present PROGPATH,a unified model capable of integrating histopathological image features with routinely collected clinical variables to achieve pancancer prognosis prediction.PROGPATH employs a weakly supervised deep learning architecture built upon the foundation model for image encoding.Morphological features are aggregated through an attention-guided multiple instance learning module and fused with clinical information via a cross-attention transformer.A router-based classification strategy further refines the prediction performance.PROGPATH was trained on 7999 whole-slide images(WSIs)from 6,670 patients across 15 cancer types,and extensively validated on 17 external cohorts with a total of 7374 WSIs from 4441 patients,covering 12 cancer types from 8 consortia and institutions across three continents.PROGPATH achieved consistently superior performance compared with state-of-the-art multimodal prognosis prediction models.It demonstrated strong generalizability across cancer types and robustness in stratified subgroups,including early-and advancedstage patients,treatment cohorts(radiotherapy and pharmaceutical therapy),and biomarker-defined subsets.We further provide model interpretability by identifying pathological patterns critical to PROGPATH’s risk predictions,such as the degree of cell differentiation and extent of necrosis.Together,these results highlight the potential of PROGPATH to support pancancer outcome prediction and inform personalized cancer management strategies.展开更多
文摘Due to the dynamic nature and node mobility,assuring the security of Mobile Ad-hoc Networks(MANET)is one of the difficult and challenging tasks today.In MANET,the Intrusion Detection System(IDS)is crucial because it aids in the identification and detection of malicious attacks that impair the network’s regular operation.Different machine learning and deep learning methodologies are used for this purpose in the conventional works to ensure increased security of MANET.However,it still has significant flaws,including increased algorithmic complexity,lower system performance,and a higher rate of misclassification.Therefore,the goal of this paper is to create an intelligent IDS framework for significantly enhancing MANET security through the use of deep learning models.Here,the min-max normalization model is applied to preprocess the given cyber-attack datasets for normalizing the attributes or fields,which increases the overall intrusion detection performance of classifier.Then,a novel Adaptive Marine Predator Optimization Algorithm(AOMA)is implemented to choose the optimal features for improving the speed and intrusion detection performance of classifier.Moreover,the Deep Supervise Learning Classification(DSLC)mechanism is utilized to predict and categorize the type of intrusion based on proper learning and training operations.During evaluation,the performance and results of the proposed AOMA-DSLC based IDS methodology is validated and compared using various performance measures and benchmarking datasets.
基金This work was partially funded by the Industry Grant Scheme from Jaycorp Berhad in cooperation with UNITAR International University.The authors would like to thank INSFORNET,the Center for Advanced Computing Technology(C-ACT)at Universiti Teknikal Malaysia Melaka(UTeM),and the Center of Intelligent and Autonomous Systems(CIAS)at Universiti Tun Hussein Onn Malaysia(UTHM)for supporting this work.
文摘With an increasing number of services connected to the internet,including cloud computing and Internet of Things(IoT)systems,the prevention of cyberattacks has become more challenging due to the high dimensionality of the network traffic data and access points.Recently,researchers have suggested deep learning(DL)algorithms to define intrusion features through training empirical data and learning anomaly patterns of attacks.However,due to the high dynamics and imbalanced nature of the data,the existing DL classifiers are not completely effective at distinguishing between abnormal and normal behavior line connections for modern networks.Therefore,it is important to design a self-adaptive model for an intrusion detection system(IDS)to improve the detection of attacks.Consequently,in this paper,a novel hybrid weighted deep belief network(HW-DBN)algorithm is proposed for building an efficient and reliable IDS(DeepIoT.IDS)model to detect existing and novel cyberattacks.The HW-DBN algorithm integrates an improved Gaussian–Bernoulli restricted Boltzmann machine(Deep GB-RBM)feature learning operator with a weighted deep neural networks(WDNN)classifier.The CICIDS2017 dataset is selected to evaluate the DeepIoT.IDS model as it contains multiple types of attacks,complex data patterns,noise values,and imbalanced classes.We have compared the performance of the DeepIoT.IDS model with three recent models.The results show the DeepIoT.IDS model outperforms the three other models by achieving a higher detection accuracy of 99.38%and 99.99%for web attack and bot attack scenarios,respectively.Furthermore,it can detect the occurrence of low-frequency attacks that are undetectable by other models.
文摘Coronavirus has infected more than 753 million people,ranging in severity from one person to another,where more than six million infected people died worldwide.Computer-aided diagnostic(CAD)with artificial intelligence(AI)showed outstanding performance in effectively diagnosing this virus in real-time.Computed tomography is a complementary diagnostic tool to clarify the damage of COVID-19 in the lungs even before symptoms appear in patients.This paper conducts a systematic literature review of deep learning methods for classifying the segmentation of COVID-19 infection in the lungs.We used the methodology of systematic reviews and meta-analyses(PRISMA)flow method.This research aims to systematically analyze the supervised deep learning methods,open resource datasets,data augmentation methods,and loss functions used for various segment shapes of COVID-19 infection from computerized tomography(CT)chest images.We have selected 56 primary studies relevant to the topic of the paper.We have compared different aspects of the algorithms used to segment infected areas in the CT images.Limitations to deep learning in the segmentation of infected areas still need to be developed to predict smaller regions of infection at the beginning of their appearance.
基金supported in part by the National Cancer Institute under award numbers R01CA268287A1,U01CA269181,R01CA26820701A1,R01CA249992-01A1,R01CA202752-01A1,R01CA208236-01A1,R01CA216579-01A1,R01CA220581-01A1,R01CA257612-01A1,1U01CA239055-01,1U01CA248226-01,1U54CA254566-01National Heart,Lung and Blood Institute 1R01HL15127701A1,R01HL15807101A1+8 种基金National Institute of Biomedical Imaging and Bioengineering 1R43EB028736-01VA Merit Review Award IBX004121A from the United States Department of Veterans Affairs Biomedical Laboratory Research and Development Service the Office of the Assistant Secretary of Defense for Health Affairs,through the Breast Cancer Research Program(W81XWH-19-1-0668)the Prostate Cancer Research Program(W81XWH-20-1-0851)the Lung Cancer Research Program(W81XWH-18-1-0440,W81XWH-20-1-0595)the Peer Reviewed Cancer Research Program(W81XWH-18-1-0404,W81XWH-21-1-0345,W81XWH-211-0160)the Kidney Precision Medicine Project(KPMP)Glue Grant and sponsored research agreements from Bristol Myers-Squibb,Boehringer-Ingelheim,Eli-Lilly and Astrazenecasupported in part by the National Natural Science Foundation of China general program(No.61571314)the Sichuan University-Yibin City Strategic Cooperation Special Fund(No.2020CDYB-27)Support Program of Sichuan Science and Technology Department(No.2023YFS0327-LH).
文摘Accurate prognosis prediction is essential for guiding cancer treatment and improving patient outcomes.While recent studies have demonstrated the potential of histopathological images in survival analysis,existing models are typically developed in a cancerspecific manner,lack extensive external validation,and often rely on molecular data that are not routinely available in clinical practice.To address these limitations,we present PROGPATH,a unified model capable of integrating histopathological image features with routinely collected clinical variables to achieve pancancer prognosis prediction.PROGPATH employs a weakly supervised deep learning architecture built upon the foundation model for image encoding.Morphological features are aggregated through an attention-guided multiple instance learning module and fused with clinical information via a cross-attention transformer.A router-based classification strategy further refines the prediction performance.PROGPATH was trained on 7999 whole-slide images(WSIs)from 6,670 patients across 15 cancer types,and extensively validated on 17 external cohorts with a total of 7374 WSIs from 4441 patients,covering 12 cancer types from 8 consortia and institutions across three continents.PROGPATH achieved consistently superior performance compared with state-of-the-art multimodal prognosis prediction models.It demonstrated strong generalizability across cancer types and robustness in stratified subgroups,including early-and advancedstage patients,treatment cohorts(radiotherapy and pharmaceutical therapy),and biomarker-defined subsets.We further provide model interpretability by identifying pathological patterns critical to PROGPATH’s risk predictions,such as the degree of cell differentiation and extent of necrosis.Together,these results highlight the potential of PROGPATH to support pancancer outcome prediction and inform personalized cancer management strategies.
