Impact statement Tolerance of high hydrostatic pressure(HHP)is the hallmark of deep subsurface microorganisms,while its mechanisms remain under-investigated.This study explores HHP adaptation in the piezotolerant bact...Impact statement Tolerance of high hydrostatic pressure(HHP)is the hallmark of deep subsurface microorganisms,while its mechanisms remain under-investigated.This study explores HHP adaptation in the piezotolerant bacterium Orenia metallireducens across its near-full pressure range(0.1-40 MPa).At inhibitory pressure(40 MPa),the organism redirected carbon flux toward more favorable energy generation and biosynthesis using ferric mineral as the“electron sink.”Furthermore,both universal and pressure-dependent strategies enabled the organism to withstand varying pressures.These findings highlight the role of iron minerals in microbial HHP adaptation and reveal novel survival strategies,advancing our understanding of deep-life evolution and biogeochemical impacts.展开更多
基金funded by the National Natural Science Foundation of China(Nos.42472366,U2444218,41877321,and 92051111)Hadal Science and Technology Research Center at Shanghai Ocean University,and the Fundamental Research Funds for the Central Universities(122-G1323522144).
文摘Impact statement Tolerance of high hydrostatic pressure(HHP)is the hallmark of deep subsurface microorganisms,while its mechanisms remain under-investigated.This study explores HHP adaptation in the piezotolerant bacterium Orenia metallireducens across its near-full pressure range(0.1-40 MPa).At inhibitory pressure(40 MPa),the organism redirected carbon flux toward more favorable energy generation and biosynthesis using ferric mineral as the“electron sink.”Furthermore,both universal and pressure-dependent strategies enabled the organism to withstand varying pressures.These findings highlight the role of iron minerals in microbial HHP adaptation and reveal novel survival strategies,advancing our understanding of deep-life evolution and biogeochemical impacts.
