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Facile synthesis of Na_(0.9)Mg_(0.45)Ti_(3.55)O_(8)-Na_(2)Ni_(2)Ti_(6)O_(16)solid solutions for improving photocatalytic CO_(2)reduction
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作者 WANG Jingzhou YAO Chenzhong +2 位作者 ZHANG Xisheng MA Ziwei LI Linfeng 《燃料化学学报(中英文)》 北大核心 2026年第1期15-25,共11页
In this study,a straightforward one-step hydrothermal method was successfully utilized to synthesize the solid solution Na_(0.9)Mg_(0.45)Ti_(3.55)O_(8)-Na_(2)Ni_(2)Ti_(6)O_(16)(NNMTO-x),where x denotes the molar perce... In this study,a straightforward one-step hydrothermal method was successfully utilized to synthesize the solid solution Na_(0.9)Mg_(0.45)Ti_(3.55)O_(8)-Na_(2)Ni_(2)Ti_(6)O_(16)(NNMTO-x),where x denotes the molar percentage of Na_(2)Ni_(2)Ti_(6)O_(16)(NNTO)within Na_(0.9)Mg_(0.45)Ti_(3.55)O_(8)(NMTO),with x values of 10,20,30,40,and 50.Both XPS(X-ray Photoelectron Spectroscopy)and EDX(Energy Dispersive X-ray Spectroscopy)analyses unequivocally validated the formation of the NNMTO-x solid solutions.It was observed that when x is below 40,the NNMTO-x solid solution retains the structural characteristics of the original NMTO.However,beyond this threshold,significant alterations in crystal morphology were noted,accompanied by a noticeable decline in photocatalytic activity.Notably,the absorption edge of NNMTO-x(x<40)exhibited a shift towards the visible-light spectrum,thereby substantially broadening the absorption range.The findings highlight that NNMTO-30 possesses the most pronounced photocatalytic activity for the reduction of CO_(2).Specifically,after a 6 h irradiation period,the production rates of CO and CH_(4)were recorded at 42.38 and 1.47μmol/g,respectively.This investigation provides pivotal insights that are instrumental in the advancement of highly efficient and stable photocatalysts tailored for CO_(2)reduction processes. 展开更多
关键词 photocatalytic conversion hydrothermal method optical response range solid solution charge separation
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Hybrid Pythagorean Fuzzy Decision-Making Framework for Sustainable Urban Planning under Uncertainty
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作者 Sana Shahab Vladimir Simic +2 位作者 Ashit Kumar Dutta Mohd Anjum Dragan Pamucar 《Computer Modeling in Engineering & Sciences》 2026年第1期892-925,共34页
Environmental problems are intensifying due to the rapid growth of the population,industry,and urban infrastructure.This expansion has resulted in increased air and water pollution,intensified urban heat island effect... Environmental problems are intensifying due to the rapid growth of the population,industry,and urban infrastructure.This expansion has resulted in increased air and water pollution,intensified urban heat island effects,and greater runoff from parks and other green spaces.Addressing these challenges requires prioritizing green infrastructure and other sustainable urban development strategies.This study introduces a novel Integrated Decision Support System that combines Pythagorean Fuzzy Sets with the Advanced Alternative Ranking Order Method allowing for Two-Step Normalization(AAROM-TN),enhanced by a dual weighting strategy.The weighting approach integrates the Criteria Importance Through Intercriteria Correlation(CRITIC)method with the Criteria Importance through Means and Standard Deviation(CIMAS)technique.The originality of the proposed framework lies in its ability to objectively quantify criteria importance using CRITIC,incorporate decision-makers’preferences through CIMAS,and capture the uncertainty and hesitation inherent in human judgment via Pythagorean Fuzzy Sets.A case study evaluating green infrastructure alternatives in metropolitan regions demonstrates the applicability and effectiveness of the framework.A sensitivity analysis is conducted to examine how variations in criteria weights affect the rankings and to evaluate the robustness of the results.Furthermore,a comparative analysis highlights the practical and financial implications of each alternative by assessing their respective strengths and weaknesses. 展开更多
关键词 Sustainable urban planning criterion importance assessment two-step normalization environmental impact decision-making
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An Integrated Approach to Condition-Based Maintenance Decision-Making of Planetary Gearboxes: Combining Temporal Convolutional Network Auto Encoders with Wiener Process
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作者 Bo Zhu Enzhi Dong +3 位作者 Zhonghua Cheng Xianbiao Zhan Kexin Jiang Rongcai Wang 《Computers, Materials & Continua》 2026年第1期661-686,共26页
With the increasing complexity of industrial automation,planetary gearboxes play a vital role in largescale equipment transmission systems,directly impacting operational efficiency and safety.Traditional maintenance s... With the increasing complexity of industrial automation,planetary gearboxes play a vital role in largescale equipment transmission systems,directly impacting operational efficiency and safety.Traditional maintenance strategies often struggle to accurately predict the degradation process of equipment,leading to excessive maintenance costs or potential failure risks.However,existing prediction methods based on statistical models are difficult to adapt to nonlinear degradation processes.To address these challenges,this study proposes a novel condition-based maintenance framework for planetary gearboxes.A comprehensive full-lifecycle degradation experiment was conducted to collect raw vibration signals,which were then processed using a temporal convolutional network autoencoder with multi-scale perception capability to extract deep temporal degradation features,enabling the collaborative extraction of longperiod meshing frequencies and short-term impact features from the vibration signals.Kernel principal component analysis was employed to fuse and normalize these features,enhancing the characterization of degradation progression.A nonlinear Wiener process was used to model the degradation trajectory,with a threshold decay function introduced to dynamically adjust maintenance strategies,and model parameters optimized through maximum likelihood estimation.Meanwhile,the maintenance strategy was optimized to minimize costs per unit time,determining the optimal maintenance timing and preventive maintenance threshold.The comprehensive indicator of degradation trends extracted by this method reaches 0.756,which is 41.2%higher than that of traditional time-domain features;the dynamic threshold strategy reduces the maintenance cost per unit time to 55.56,which is 8.9%better than that of the static threshold optimization.Experimental results demonstrate significant reductions in maintenance costs while enhancing system reliability and safety.This study realizes the organic integration of deep learning and reliability theory in the maintenance of planetary gearboxes,provides an interpretable solution for the predictive maintenance of complex mechanical systems,and promotes the development of condition-based maintenance strategies for planetary gearboxes. 展开更多
关键词 Temporal convolutional network autoencoder full lifecycle degradation experiment nonlinear Wiener process condition-based maintenance decision-making fault monitoring
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Existence,Uniqueness and Stability of Bounded Solutions for Minkowski-Curvature Problems with Asymptotic Boundary Conditions
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作者 Tianlan CHEN Xuying TANG 《Journal of Mathematical Research with Applications》 2026年第1期57-70,共14页
In this article,we show the existence,uniqueness and stability of bounded solutions to the following quasilinear problems with mean curvature operator(φ'(x′(t)))′=f(t,x),t≥t_(0),lim_(t→∞)x(t)=ψ_(0),lim_(t→... In this article,we show the existence,uniqueness and stability of bounded solutions to the following quasilinear problems with mean curvature operator(φ'(x′(t)))′=f(t,x),t≥t_(0),lim_(t→∞)x(t)=ψ_(0),lim_(t→∞)x′(t)e^(t)=0,where t_(0) and ψ_(0) are real constants,φ(s)=s/√1−s^(2),s∈R with s∈(−1,1),f:[t_(0),∞)×R→R satisfies the Lipschitz or Osgood-type conditions. 展开更多
关键词 mean curvature operator UNIQUENESS asymptotic boundary conditions bounded solution
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Solution set of circumlunar abort trajectory and its direct application to optimization design
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作者 Tianshan DONG Zhen HUANG +2 位作者 Wenyan ZHOU Xiangyu ZHANG Lin LU 《Chinese Journal of Aeronautics》 2026年第1期333-348,共16页
Circumlunar abort trajectories constitute a vital contingency return strategy during the translunar phase of crewed lunar missions.This paper proposes a methodology for constructing the solution set of the circumlunar... Circumlunar abort trajectories constitute a vital contingency return strategy during the translunar phase of crewed lunar missions.This paper proposes a methodology for constructing the solution set of the circumlunar abort trajectory and leverages its advantageous properties to address the optimization design problem of abort trajectories.Initially,a solution set of all feasible abort trajectories,originating from an abort point on the nominal trajectory and complying with fundamental reentry constraints,is formulated through the introduction of two novel design parameters.Subsequently,the geometric characteristics of the solution set,as well as the distributional properties of key iterative constraint responses,including flight time and velocity increment,are analyzed.Finally,the characteristics exhibited in the solution set are employed to directly identify the design parameters of the abort trajectories with minimum flight time and velocity increment,thereby providing solutions to two distinct types of optimization problems.The simulation results for a variety of nominal trajectories,encompassing the reconstruction and redesign of the Apollo13 abort trajectory,validate the proposed method,demonstrating its ability to directly generate optimal abort trajectories.The method proposed in this paper investigates feasible abort trajectories from a global perspective,providing both a framework and convenience for mission planning and iterative optimization in abort trajectory design. 展开更多
关键词 Circumlunar abort trajectory Design parameters Geometric characteristics Optimization problems solution set
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Analytical solution for longitudinal responses of tunnels under combined effects of seismic waves and strike-slip faulting
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作者 Jie Tang Manchao He +2 位作者 Yafei Qiao Hanbing Bian Chun Zhu 《Journal of Rock Mechanics and Geotechnical Engineering》 2026年第2期1266-1289,共24页
Strong seismic excitation and fault dislocation are likely to occur simultaneously in high-intensity seismic zones,causing severe damage to tunnels crossing active fault zones.This paper aims to develop a novel analyt... Strong seismic excitation and fault dislocation are likely to occur simultaneously in high-intensity seismic zones,causing severe damage to tunnels crossing active fault zones.This paper aims to develop a novel analytical solution to determine the longitudinal mechanical responses of tunnels subjected to the combined effects of seismic waves and strike-slip faulting.Adopting the elastic springbeam model,the seismic waves are modelled as shear horizontal(SH)waves and the fault dislocation follows an S-shaped pattern;the superposition principle for free-fielddisplacements caused by both effects is assumed.In addition,the transmission and reflectionof seismic waves at the fault-rock geological interface and the tangential contact conditions at the tunnel-rock interface are considered.The analytical model is validated against numerical simulations,confirmingits accuracy in calculating tunnel responses.Moreover,a parametric study is conducted to evaluate the impact of key factors,including fault displacement,fault zone width,fault dip angle,earthquake frequency,rock conditions,tunnel lining stiffness,and tangential contact conditions,on tunnel responses.Compared with each effect alone,the combined effects of seismic waves and strike-slip faulting significantlychange the tunnel deformation and internal forces,leading to increased tunnel responses,especially within the fault zone and near the fault-rock interfaces.Depending on specificparameters,tunnel responses can be classifiedinto seismic-dominated,faulting-dominated,and seismic-faulting coupled responses on the basis of the relative contributions of each effect.The proposed analytical solution can be applied to quickly predict the longitudinal mechanical behaviour of tunnels under such combined effects in engineering applications. 展开更多
关键词 Strike-slip faulting Longitudinal tunnel response Analytical solution Seismic waves Wave transmissions and reflections
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Optimal combination of substrate supply amount coupled with nutrient solution management program for cucumber planting
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作者 Zhen Kang Zhaoxi Jiang +5 位作者 Zhaolong Liu Peng Wang Caihong Zhang Maozhou Yuan Mengqi Bai Xiaohui Hu 《Horticultural Plant Journal》 2026年第1期136-148,共13页
Substrate and nutrient supply are essential for vegetable cultivation in greenhouse.The strategies for plant nutrient supply vary depending on the cultivation methods or substrate dosages employed.With the development... Substrate and nutrient supply are essential for vegetable cultivation in greenhouse.The strategies for plant nutrient supply vary depending on the cultivation methods or substrate dosages employed.With the development of mechanization,wide-row spacing substrate cultivation became an optimize mode of the greenhouse cucumber cultivation,aligning with the trend of intelligent agriculture.To determine the optimal nutrient solution supply amount(NS)and supply frequency(SF)for promoting the integrated growth of cucumber under wide-row spacing substrate cultivation,we explored the effects of substrate supply amount(SS),NS,and SF on cucumber yield,quality,and element utilization efficiency.A five-level quadratic orthogonal rotation combination design with three experimental factors(NS,SF,and SS)was implemented for 23 coupling treatments over three growing seasons,including spring(2022S and 2023S)and autumn(2022A).The technique for order preference by similarity to ideal solution(TOPSIS)combining weights based on game theory was applied to construct cucumber comprehensive growth evaluation model.Single and two experimental factors analyses revealed significant effects of single factors and the coupling of NS-SS,NS-SF and SS-SF on the integrated growth of cucumber for all three growing seasons.For the NS-SF-SS combination,the optimal parameters for comprehensive cucumber growth were determined as follows:levels of^(-1).68 for NS,-0.7 for SF,and^(-1).682 for SS in 2022A;-0.43 for NS,-0.06 for SF,and 0.34 for SS in 2022S;0.3 for NS,-0.02 for SF,and 0.04 for SS in 2023S.Furthermore,for SS ranges of 2.00-3.01,3.01-4.50,4.50-5.99,5.99-7.00(L·plant^(-1)),the corresponding NS and SF intervals maximizing cucumber integrated growth in spring were:0.28-0.30(L·plant^(-1))and 6(times·d^(-1)),0.26-0.30(L·plant^(-1))and 6(times·d^(-1)),0.25-0.30(L·plant^(-1))and 6(times·d^(-1)),0.23-0.30(L·plant^(-1))and 6(times·d^(-1)),respectively.With the same SS,the corresponding NS and SF intervals that maximized cucumber integrated growth in autumn were:0.10(L·plant^(-1))and 8(times·d^(-1)),0.18(L·plant^(-1))and 7(times·d^(-1)),0.30(L·plant^(-1))and 6(times·d^(-1)),0.49(L·plant^(-1))and 5(times·d^(-1)),respectively.The results provide a theoretical basis for solution management,and further in-depth research on cucumber cultivation. 展开更多
关键词 Cucumis sativus L. Comprehensive growth Irrigation frequency Nutrient solution Substrate supply amount Wide row spacing
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Tailoring oxygen vacancies in Ni-doped In_(2)O_(3) for improved thin-film transistor stability and performance via solution processing
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作者 Fakhari Alam Sara Ajmal +3 位作者 Muhammad Asim Shahzad Ghulam Dastgeer Aamir Rasheed Gang He 《Journal of Semiconductors》 2026年第2期61-71,共11页
Doping in thin-film transistors(TFTs) plays a crucial role in tailoring material properties to enhance device performance, making them essential for advanced electronic applications. This study explores the synthesis ... Doping in thin-film transistors(TFTs) plays a crucial role in tailoring material properties to enhance device performance, making them essential for advanced electronic applications. This study explores the synthesis and characterization of TFTs fabricated using nickel(Ni)-doped indium oxide(In_(2)O_(3)) via a wet-chemical approach. The presented work investigates the effect of "Ni" incorporation in In_(2)O_(3) on the structural and electrical transport properties of In_(2)O_(3), revealing that higher "Ni" content decreases the oxygen vacancies, leading to a reduction in leakage current and a forward shift in threshold potential(V_(th)).Experimental findings reveal that Ni In O-based TFTs(with Ni = 0.5%) showcase enhanced electrical performance, achieving mobility of 7.54 cm^(2)/(V·s), an impressive ON/OFF current ratio of ~10^(7), a V_(th) of 6.26 V, reduced interfacial trap states(D_(it)) of 8.23 ×10^(12) cm^(-2) and enhanced biased stress stability. The efficacy of "Ni" incorporation is attributed to the upgraded Lewis acidity, stable Ni-O bond strength, and small ionic radius of Ni. Negative bias illumination stability(NBIS) measurements further indicate that device stability diminishes with shorter light wavelengths, likely due to the activation of oxygen vacancies. These findings validate the solution-processed techniques' potential for future large-scale, low-cost, energy-efficient, and high-performance electronics. 展开更多
关键词 thin-film transistors Ni-doped In_(2)O_(3) solution processing bias illumination stability
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In-situ stress solution theory for borehole overcoring technique incorporating time-dependent effect of stress relief and its applications
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作者 Daohong Xia Shengjun Miao +5 位作者 Lianjun Chen Yuan Li Zejing Liu Rongmin Zhang Pengjin Yang Pengcheng Li 《International Journal of Mining Science and Technology》 2026年第1期187-203,共17页
In-situ stress is a key parameter for underground mine design and rock stability analysis.The borehole overcoring technique is widely used for in-situ stress measurement,but the rheological recovery deformation of roc... In-situ stress is a key parameter for underground mine design and rock stability analysis.The borehole overcoring technique is widely used for in-situ stress measurement,but the rheological recovery deformation of rocks after stress relief introduces errors.To improve accuracy,this study proposes an in-situ stress solution theory that incorporates time-dependent stress relief effects.Triaxial stepwise loadingunloading rheological tests on granite and siltstone established quantitative relationships between instantaneous elastic recovery and viscoelastic recovery under different stress levels,confirming their impact on measurement accuracy.By integrating a dual-class elastic deformation recovery model,an improved in-situ stress solution theory was derived.Additionally,accounting for the nonlinear characteristics of rock masses,a determination method for time-dependent nonlinear mechanical parameters was proposed.Based on the CSIRO hollow inclusion strain cell,time-dependent strain correction equations and long-term confining pressure calibration equations were formulated.Finally,the proposed theory was successfully applied at one iron mine(736 m depth)in Xinjiang,China,and one coal mine(510 m depth)in Ningxia,China.Compared to classical theory,the calculated mean stress values showed accuracy improvements of 6.0%and 9.4%,respectively,validating the applicability and reliability of the proposed theory. 展开更多
关键词 In-situ stress solution theory Borehole overcoring technique Time-dependent effect of stress relief Viscoelastic recovery strain of rock In-situ stress measurement
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Multimodal fluorescent switch:pressure-induced emission and solution-induced optical anti-counterfeiting and logic gates
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作者 Jingtian Wang Xihan Yu +2 位作者 Kai Wang Guanjun Xiao Bo Zou 《Science Bulletin》 2026年第3期490-494,共5页
Multifunctional optical responsive materials have grown increasingly pivotal in addressingthe escalating demands of sensing,detection,and anti-counterfeiting applications[1,2].These materials exhibit distinct visible ... Multifunctional optical responsive materials have grown increasingly pivotal in addressingthe escalating demands of sensing,detection,and anti-counterfeiting applications[1,2].These materials exhibit distinct visible optical variations upon exposure to external stimuli,such as pressure,temperature,light,solvents,pH fluctuations,or mechanical force.Fluorescent sensing and anti-counterfeiting technologies leveraging these optical responses have emerged as highly promising solutions. 展开更多
关键词 sensing multifunctional optical responsive materials logic gates optical responsive materials multimodal fluorescent switch optical variations pressure induced emission solution induced optical anti counterfeiting
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Effect and mechanism of Ti−O solid solution layer on interfacial bonding strength of cold roll bonded titanium/stainless steel laminated composite plate
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作者 Zhi-yan YANG Xue-feng LIU +1 位作者 Hong-ting CHEN Xin MA 《Transactions of Nonferrous Metals Society of China》 2026年第1期171-182,共12页
Titanium plates with a Ti−O solid solution surface-hardened layer were cold roll-bonded with 304 stainless steel plates with high work hardening rates.The evolution and mechanisms affecting the interfacial bonding str... Titanium plates with a Ti−O solid solution surface-hardened layer were cold roll-bonded with 304 stainless steel plates with high work hardening rates.The evolution and mechanisms affecting the interfacial bonding strength in titanium/stainless steel laminated composites were investigated.Results indicate that the hardened layer reduces the interfacial bonding strength from over 261 MPa to less than 204 MPa.During the cold roll-bonding process,the hardened layer fractures,leading to the formation of multi-scale cracks that are difficult for the stainless steel to fill.This not only hinders the development of an interlocking interface but also leads to the presence of numerous microcracks and hardened blocks along the nearly straight interface,consequently weakening the interfacial bonding strength.In metals with high work hardening rates,the conventional approach of enhancing interface interlocking and improving interfacial bonding strength by using a surface-hardened layer becomes less effective. 展开更多
关键词 titanium/stainless steel laminated composite plate Ti−O solid solution hardened layer interlocking interface formation mechanism interfacial bonding strength
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Solutions of three-body problem based on an equivalent system approach
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作者 Jing Tang Xing 《Acta Mechanica Sinica》 2026年第1期292-309,共18页
Generalised reduced masses with a set of equations governing the three relative motions between two of 3-bodies in their gravitational field are established,of which the dynamic characteristics of 3-body dynamics,fund... Generalised reduced masses with a set of equations governing the three relative motions between two of 3-bodies in their gravitational field are established,of which the dynamic characteristics of 3-body dynamics,fundamental bases of this paper,are revealed.Based on these findings,an equivalent system is developed,which is a 2-body system with its total mass,constant angular momentum,kinetic and potential energies same as the total ones of three relative motions,so that it can be solved using the well-known theory of the 2-body system.From the solution of an equivalent system with the revealed characteristics of three relative motions,the general theoretical solutions of the 3-body system are obtained in the curve-integration forms along the orbits in the imaged radial motion space.The possible periodical orbits with generalised Kepler’s law are presented.Following the description and mathematical demonstrations of the proposed methods,the examples including Euler’s/Lagrange’s problems,and a reported numerical one are solved to validate the proposed methods.The methods derived from the 3-body system are extended to N-body problems. 展开更多
关键词 Three-body problem Equivalent system with solutions Orbit-equation of a conic section Generalised reduced mass Chaotic motions Generalised Kepler’s law N-body problem
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A trajectory data warehouse solution for workforce management decision-making 被引量:1
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作者 Georgia Garani Dimitrios Tolis Ilias K.Savvas 《Data Science and Management》 2023年第2期88-97,共10页
In modern workforce management,the demand for new ways to maximize worker satisfaction,productivity,and security levels is endless.Workforce movement data such as those source data from an access control system can su... In modern workforce management,the demand for new ways to maximize worker satisfaction,productivity,and security levels is endless.Workforce movement data such as those source data from an access control system can support this ongoing process with subsequent analysis.In this study,a solution to attaining this goal is proposed,based on the design and implementation of a data mart as part of a dimensional trajectory data warehouse(TDW)that acts as a repository for the management of movement data.A novel methodological approach is proposed for modeling multiple spatial and temporal dimensions in a logical model.The case study presented in this paper for modeling and analyzing workforce movement data is to support human resource management decision-making and the following discussion provides a representative example of the contribution of a TDW in the process of information management and decision support systems.The entire process of exporting,cleaning,consolidating,and transforming data is implemented to achieve an appropriate format for final import.Structured query language(SQL)queries demonstrate the convenience of dimensional design for data analysis,and valuable information can be extracted from the movements of employees on company premises to manage the workforce efficiently and effectively.Visual analytics through data visualization support the analysis and facilitate decisionmaking and business intelligence. 展开更多
关键词 Business intelligence decision-making Workforce management Trajectory data warehouse(TDW) Moving object Semantic modeling
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Application of Fuzzy Decision-Making Theory and Conflict-Resolution Method to Failure Mode and Effect Analysis of Industrial Valve
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作者 吴世青 沈斌 +3 位作者 王家海 郑大腾 KUNZE Markus FLEISCHER Juergen 《Journal of Donghua University(English Edition)》 EI CAS 2017年第2期184-188,共5页
It is not objective to rate the decision-making factors in the traditional failure mode and effect analysis,so fuzzy semantic theory is used in this paper.Six fuzzy semantic scales and their corresponding semantics ar... It is not objective to rate the decision-making factors in the traditional failure mode and effect analysis,so fuzzy semantic theory is used in this paper.Six fuzzy semantic scales and their corresponding semantics are summarized,and a defuzzification method is studied to obtain the fuzzy value table of the six fuzzy semantic scales.For the conflicts between experts in the traditional failure mode and effects analysis,a conflict-resolution algorithm is studied to obtain the failure risk order.Finally,a certain type of industrial valve is used as an example to prove the validity of the theory proposed in this paper. 展开更多
关键词 failure mode and effect analysis fuzzy semantic multiobject decision-making conflict-resolution
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Kangfuxin solution alleviates esophageal stenosis after endoscopic submucosal dissection:A natural ingredient strategy 被引量:2
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作者 Xin Zhou Dan Ma +7 位作者 Yi-Xiang He Jing Jin Hong-Lian Wang Yun-Feng Wang Fan Yang Jian-Qin Liu Jie Chen Zhi Li 《World Journal of Gastroenterology》 SCIE CAS 2025年第1期110-125,共16页
BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after ESD.... BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after ESD.AIM To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus post-ESD.METHODS Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential ESD.Endoscopic examinations occurred on days 7 and 21 post-ESD.In vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was assessed.Profibrotic signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after ESD.After treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal layer.Additionally,the expression of fibrotic effector molecules was notably inhibited.Mechanistically,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/3.In vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen I.The 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated pEsF.CONCLUSION KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway. 展开更多
关键词 Kangfuxin solution Natural component Endoscopic submucosal dissection Esophagus stricture Fibrosis
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Voices that matter:The impact of patient-reported outcome measures on clinical decision-making 被引量:1
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作者 Naveen Jeyaraman Madhan Jeyaraman +2 位作者 Swaminathan Ramasubramanian Sangeetha Balaji Sathish Muthu 《World Journal of Methodology》 2025年第2期54-61,共8页
The critical role of patient-reported outcome measures(PROMs)in enhancing clinical decision-making and promoting patient-centered care has gained a profound significance in scientific research.PROMs encapsulate a pati... The critical role of patient-reported outcome measures(PROMs)in enhancing clinical decision-making and promoting patient-centered care has gained a profound significance in scientific research.PROMs encapsulate a patient's health status directly from their perspective,encompassing various domains such as symptom severity,functional status,and overall quality of life.By integrating PROMs into routine clinical practice and research,healthcare providers can achieve a more nuanced understanding of patient experiences and tailor treatments accordingly.The deployment of PROMs supports dynamic patient-provider interactions,fostering better patient engagement and adherence to tre-atment plans.Moreover,PROMs are pivotal in clinical settings for monitoring disease progression and treatment efficacy,particularly in chronic and mental health conditions.However,challenges in implementing PROMs include data collection and management,integration into existing health systems,and acceptance by patients and providers.Overcoming these barriers necessitates technological advancements,policy development,and continuous education to enhance the acceptability and effectiveness of PROMs.The paper concludes with recommendations for future research and policy-making aimed at optimizing the use and impact of PROMs across healthcare settings. 展开更多
关键词 Patient-reported outcome measures Clinical decision-making Patient-centered care Healthcare technology Data management Policy development
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Ascorbic acid-induced porous iodide layer for a high-purity two-step solution-processed tin-lead mixed perovskite photodetector 被引量:2
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作者 Liansong Liu Fengren Cao +3 位作者 Liukang Bian Meng Wang Haoxuan Sun Liang Li 《Journal of Materials Science & Technology》 2025年第7期227-232,共6页
Tin(Sn)-lead(Pb)mixed halide perovskites have attracted widespread interest due to their wider re-sponse wavelength and lower toxicity than lead halide perovskites,Among the preparation methods,the two-step method mor... Tin(Sn)-lead(Pb)mixed halide perovskites have attracted widespread interest due to their wider re-sponse wavelength and lower toxicity than lead halide perovskites,Among the preparation methods,the two-step method more easily controls the crystallization rate and is suitable for preparing large-area per-ovskite devices.However,the residual low-conductivity iodide layer in the two-step method can affect carrier transport and device stability,and the different crystallization rates of Sn-and Pb-based per-ovskites may result in poor film quality.Therefore,Sn-Pb mixed perovskites are mainly prepared by a one-step method.Herein,a MAPb_(0.5)Sn_(0.5)I_(3)-based self-powered photodetector without a hole transport layer is fabricated by a two-step method.By adjusting the concentration of the ascorbic acid(AA)addi-tive,the final perovskite film exhibited a pure phase without residues,and the optimal device exhibited a high responsivity(0.276 A W^(-1)),large specific detectivity(2.38×10^(12) Jones),and enhanced stability.This enhancement is mainly attributed to the inhibition of Sn2+oxidation,the control of crystal growth,and the sufficient reaction between organic ammonium salts and bottom halides due to the AA-induced pore structure. 展开更多
关键词 PEROVSKITE SN-PB PHOTODETECTOR Two-step solution method
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Rule-Guidance Reinforcement Learning for Lane Change Decision-making:A Risk Assessment Approach 被引量:1
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作者 Lu Xiong Zhuoren Li +2 位作者 Danyang Zhong Puhang Xu Chen Tang 《Chinese Journal of Mechanical Engineering》 2025年第2期344-359,共16页
To solve problems of poor security guarantee and insufficient training efficiency in the conventional reinforcement learning methods for decision-making,this study proposes a hybrid framework to combine deep reinforce... To solve problems of poor security guarantee and insufficient training efficiency in the conventional reinforcement learning methods for decision-making,this study proposes a hybrid framework to combine deep reinforcement learning with rule-based decision-making methods.A risk assessment model for lane-change maneuvers considering uncertain predictions of surrounding vehicles is established as a safety filter to improve learning efficiency while correcting dangerous actions for safety enhancement.On this basis,a Risk-fused DDQN is constructed utilizing the model-based risk assessment and supervision mechanism.The proposed reinforcement learning algorithm sets up a separate experience buffer for dangerous trials and punishes such actions,which is shown to improve the sampling efficiency and training outcomes.Compared with conventional DDQN methods,the proposed algorithm improves the convergence value of cumulated reward by 7.6%and 2.2%in the two constructed scenarios in the simulation study and reduces the number of training episodes by 52.2%and 66.8%respectively.The success rate of lane change is improved by 57.3%while the time headway is increased at least by 16.5%in real vehicle tests,which confirms the higher training efficiency,scenario adaptability,and security of the proposed Risk-fused DDQN. 展开更多
关键词 Autonomous driving Reinforcement learning decision-making Risk assessment Safety filter
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Synergistic effect of infinite and finite solid solution enabling ultrathin Li-Cu-Ag alloy toward advanced Li metal anode 被引量:1
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作者 Xiao-Xiao Chen Hao Huang +6 位作者 Lin-Yun Yi Zi-Hao Wang Zhi-Cui Song Jian-Xiong Xing Chao-Hui Wei Ai-Jun Zhou Jing-Ze Li 《Rare Metals》 2025年第1期121-134,共14页
Ultrathin Li-rich Li-Cu binary alloy has become a competitive anode material for Li metal batteries of high energy density.However,due to the poor-lithiophilicity of the single skeleton structure of Li-Cu alloy,it has... Ultrathin Li-rich Li-Cu binary alloy has become a competitive anode material for Li metal batteries of high energy density.However,due to the poor-lithiophilicity of the single skeleton structure of Li-Cu alloy,it has limitations in inducing Li nucleation and improving electrochemical performance.Hence,we introduced Ag species to Li-Cu alloy to form a 30μm thick Li-rich Li-Cu-Ag ternary alloy(LCA)anode,with Li-Ag infinite solid solution as the active phase,and Cu-based finite solid solutions as three-dimensional(3D)skeleton.Such nano-wire networks with LiCu4 and CuxAgy finite solid solution phases were prepared through a facile melt coating technique,where Ag element can act as lithiophilic specie to enhance the lithiophilicity of built-in skeleton,and regulate the deposition behavior of Li effectively.Notably,the formation of CuxAgy solid solution can strengthen the structural stability of the skeleton,ensuring the geometrical integrity of Li anode,even at the fully delithiated state.Meanwhile,the Li-Ag infinite solid solution phase can promote the Li plating/stripping reversibility of the LCA anode with an improved coulombic efficiency(CE).The synergistic effect between infinite and finite solid solutions could render an enhanced electrochemical performance of Li metal batteries.The LCA|LCA symmetric cells showed a long lifespan of over 600 h with stable polarization voltage of 40 mV,in 1 mA·cm^(-2)/1 mAh·cm^(-2).In addition,the full cells matching our ultrathin LCA anode with 17.2 mg·cm^(-2)mass loading of LiFePO_(4) cathode,can continuously operate beyond 110 cycles at 0.5C,with a high capacity retention of 91.5%.Kindly check and confirm the edit made in the article title. 展开更多
关键词 Li alloy anode Solid solution solution strengthening Lithiophilic skeleton Ternary alloy
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Colorectal cancer early screening:Dilemmas and solutions 被引量:2
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作者 Di Wu Qi-Ying Song +4 位作者 Bai-Shu Dai Jie Li Xin-Xin Wang Jia-Yu Liu Tian-Yu Xie 《World Journal of Gastroenterology》 2025年第9期154-160,共7页
Colorectal cancer(CRC)is a prevalent malignancy worldwide,posing a significant public health concern.Mounting evidence has confirmed that timely early screening facilitates the detection of incipient CRC,thereby enhan... Colorectal cancer(CRC)is a prevalent malignancy worldwide,posing a significant public health concern.Mounting evidence has confirmed that timely early screening facilitates the detection of incipient CRC,thereby enhancing patient prognosis.Obviously,non-participation of asymptomatic individuals in screening programs hampers early diagnosis and may adversely affect long-term outcomes for CRC patients.In this letter,we provide a comprehensive overview of the current status of early screening practices,while also thoroughly examine the dilemmas and potential solutions associated with early screening for CRC.In response to these issues,we proffer a set of recommendations directed at governmental authorities and the general public,which focus on augmenting financial investment,establishing standardized screening protocols,advancing technological capabilities,and bolstering public awareness campaigns.The importance of collaborative efforts from various stakeholders cannot be overstated in the quest to enhance early detection rates and alleviate the societal burden of CRC. 展开更多
关键词 Colorectal cancer Early screening Asymptomatic candidates DILEMMAS solutionS
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