This study was to investigate the changes of autonomic nerve function and hemodynamics in patients with vasovagal syncope(VVS) during head-up tilt-table testing(HUT). HUT was performed in 68 patients with unexplained ...This study was to investigate the changes of autonomic nerve function and hemodynamics in patients with vasovagal syncope(VVS) during head-up tilt-table testing(HUT). HUT was performed in 68 patients with unexplained syncope and 18 healthy subjects served as control group. According to whether bradycardia, hypotension or both took place during the onset of syncope, the patients were divided during the test into three subgroups: vasodepressor syncope(VD), cardioinhibitory syncope(CI) and mixed syncope(MX) subgroups. Heart rate, blood pressure, heart rate variability(HRV), and deceleration capacity(DC) were continuously analyzed during HUT. For all the subjects with positive responses, the normalized low frequency(LFn) and the LF/HF ratio markedly decreased whereas normalized high frequency(HFn) increased when syncope occurred. Syncopal period also caused more significant increase in the power of the DC in positive groups. These changes were more exaggerated compared to controls. All the patients were indicative of a sympathetic surge in the presence of withdrawal vagal activity before syncope and a sympathetic inhibition with a vagal predominance at the syncopal stage by the frequency-domain analysis of HRV. With the measurements of DC, a decreased vagal tone before syncope stage and a vagal activation at the syncopal stage were observed. The vagal tone was higher in subjects showing cardioinhibitory responses at the syncopal stage. DC may provide an alternative method to understand the autonomic profile of VVS patients.展开更多
As a common transportation facility, speed humps can control the speed of vehicles on special road sections to reduce traffic risks. At the same time, they also cause instantaneous traffic emissions. Based on the clas...As a common transportation facility, speed humps can control the speed of vehicles on special road sections to reduce traffic risks. At the same time, they also cause instantaneous traffic emissions. Based on the classic instantaneous traffic emission model and the limited deceleration capacity microscopic traffic flow model with slow-to-start rules, this paper has investigated the impact of speed humps on traffic flow and the instantaneous emissions of vehicle pollutants in a single lane situation. The numerical simulation results have shown that speed humps have significant effects on traffic flow and traffic emissions. In a free-flow region, the increase of speed humps leads to the continuous rise of CO_(2), NO_(X) and PM emissions. Within some density ranges, one finds that these pollutant emissions can evolve into some higher values under some random seeds. Under other random seeds, they can evolve into some lower values. In a wide moving jam region, the emission values of these pollutants sometimes appear as continuous or intermittent phenomenon. Compared to the refined Na Sch model, the present model has lower instantaneous emissions such as CO_(2), NO_(X) and PM and higher volatile organic components(VOC) emissions. Compared to the limited deceleration capacity model without slow-to-start rules, the present model also has lower instantaneous emissions such as CO_(2), NO_(X) and PM and higher VOC emissions in a wide moving jam region. These results can also be confirmed or explained by the statistical values of vehicle velocity and acceleration.展开更多
A novel deceleration traffic flow model is established based on the oscillatory congested states and the slow-tostart rule.The novel model considers human overreaction and mechanical restrictions as limited decelerati...A novel deceleration traffic flow model is established based on the oscillatory congested states and the slow-tostart rule.The novel model considers human overreaction and mechanical restrictions as limited deceleration capacity,effectively avoiding the unrealistic deceleration behavior found in most existing traffic flow models.In order to consider that the acceleration of a stationary vehicle is slower than that of a moving vehicle due to reasons such as driver inattention,the slow-to-start rule is introduced.In actual traffic,the driver will take different deceleration measures according to local traffic conditions,divided into ordinary and emergency deceleration.The deceleration setting in the deceleration model with only ordinary deceleration is modified.Computer simulations show that the novel model can achieve smooth,comfortable acceleration and deceleration behavior.Introducing the slow-to-start rule can realize the first-order transition from free flow to synchronized flow.The oscillatory congested states enable a first-order transition from synchronized flow to wide moving jam.Under periodic boundary conditions,the novel model can reproduce three traffic flow phases(free flow,synchronized flow,and wide moving jam)and two first-order transitions between three phases.In addition,the novel model can reproduce empirical results such as linear synchronized flow and headway distribution of free flow below 1 s.Under open boundary conditions,different congested patterns caused by on-ramps are analyzed.Compared with the classic deceleration model,this model can better reproduce the phenomenon and characteristics of actual traffic flow and provide more accurate decision support for daily traffic management of expressways.展开更多
基金supported by a grant from the Wuhan Science and Technology Program of China(No.2014060101010032)
文摘This study was to investigate the changes of autonomic nerve function and hemodynamics in patients with vasovagal syncope(VVS) during head-up tilt-table testing(HUT). HUT was performed in 68 patients with unexplained syncope and 18 healthy subjects served as control group. According to whether bradycardia, hypotension or both took place during the onset of syncope, the patients were divided during the test into three subgroups: vasodepressor syncope(VD), cardioinhibitory syncope(CI) and mixed syncope(MX) subgroups. Heart rate, blood pressure, heart rate variability(HRV), and deceleration capacity(DC) were continuously analyzed during HUT. For all the subjects with positive responses, the normalized low frequency(LFn) and the LF/HF ratio markedly decreased whereas normalized high frequency(HFn) increased when syncope occurred. Syncopal period also caused more significant increase in the power of the DC in positive groups. These changes were more exaggerated compared to controls. All the patients were indicative of a sympathetic surge in the presence of withdrawal vagal activity before syncope and a sympathetic inhibition with a vagal predominance at the syncopal stage by the frequency-domain analysis of HRV. With the measurements of DC, a decreased vagal tone before syncope stage and a vagal activation at the syncopal stage were observed. The vagal tone was higher in subjects showing cardioinhibitory responses at the syncopal stage. DC may provide an alternative method to understand the autonomic profile of VVS patients.
基金funded by the National Natural Science Foundation of China (Grant No. 11875031)the key research projects of Natural Science of Anhui Provincial Colleges and Universities (Grant No. 2022AH050252)。
文摘As a common transportation facility, speed humps can control the speed of vehicles on special road sections to reduce traffic risks. At the same time, they also cause instantaneous traffic emissions. Based on the classic instantaneous traffic emission model and the limited deceleration capacity microscopic traffic flow model with slow-to-start rules, this paper has investigated the impact of speed humps on traffic flow and the instantaneous emissions of vehicle pollutants in a single lane situation. The numerical simulation results have shown that speed humps have significant effects on traffic flow and traffic emissions. In a free-flow region, the increase of speed humps leads to the continuous rise of CO_(2), NO_(X) and PM emissions. Within some density ranges, one finds that these pollutant emissions can evolve into some higher values under some random seeds. Under other random seeds, they can evolve into some lower values. In a wide moving jam region, the emission values of these pollutants sometimes appear as continuous or intermittent phenomenon. Compared to the refined Na Sch model, the present model has lower instantaneous emissions such as CO_(2), NO_(X) and PM and higher volatile organic components(VOC) emissions. Compared to the limited deceleration capacity model without slow-to-start rules, the present model also has lower instantaneous emissions such as CO_(2), NO_(X) and PM and higher VOC emissions in a wide moving jam region. These results can also be confirmed or explained by the statistical values of vehicle velocity and acceleration.
基金supported by the National Natural Science Foundation of China(Grant No.71671109)the National Key Research and Development Program of China(Grant No.2020YFB1600500)the Key Research and Development Program of Heilongjiang Province,China(Grant No.GZ20220089)。
文摘A novel deceleration traffic flow model is established based on the oscillatory congested states and the slow-tostart rule.The novel model considers human overreaction and mechanical restrictions as limited deceleration capacity,effectively avoiding the unrealistic deceleration behavior found in most existing traffic flow models.In order to consider that the acceleration of a stationary vehicle is slower than that of a moving vehicle due to reasons such as driver inattention,the slow-to-start rule is introduced.In actual traffic,the driver will take different deceleration measures according to local traffic conditions,divided into ordinary and emergency deceleration.The deceleration setting in the deceleration model with only ordinary deceleration is modified.Computer simulations show that the novel model can achieve smooth,comfortable acceleration and deceleration behavior.Introducing the slow-to-start rule can realize the first-order transition from free flow to synchronized flow.The oscillatory congested states enable a first-order transition from synchronized flow to wide moving jam.Under periodic boundary conditions,the novel model can reproduce three traffic flow phases(free flow,synchronized flow,and wide moving jam)and two first-order transitions between three phases.In addition,the novel model can reproduce empirical results such as linear synchronized flow and headway distribution of free flow below 1 s.Under open boundary conditions,different congested patterns caused by on-ramps are analyzed.Compared with the classic deceleration model,this model can better reproduce the phenomenon and characteristics of actual traffic flow and provide more accurate decision support for daily traffic management of expressways.
