Epithelial-mesenchymal transition(EMT)is a critical cellular process in embryonic development and is also the basis for wound repair,tissue regeneration,and cancer metastasis(Zhao et al.,2015).During cancer migration ...Epithelial-mesenchymal transition(EMT)is a critical cellular process in embryonic development and is also the basis for wound repair,tissue regeneration,and cancer metastasis(Zhao et al.,2015).During cancer migration and invasion,EMT involved comprehensive reprogramming processes related to cytoskeletal remodeling,cell differentiation,epigenetic regulation and metabolism(Plikus et al.,2015).In fact,the understanding of EMT in cancer development is still limited.In 2015.展开更多
基金supported by the National Natural Science Foundation of China(Nos.31671375,31871339 and 31801120)the National Key Research and Development Program of China(No.2017YFC1201200)the research start-up fellowship of University of the Sunshine Coast to MZ.
文摘Epithelial-mesenchymal transition(EMT)is a critical cellular process in embryonic development and is also the basis for wound repair,tissue regeneration,and cancer metastasis(Zhao et al.,2015).During cancer migration and invasion,EMT involved comprehensive reprogramming processes related to cytoskeletal remodeling,cell differentiation,epigenetic regulation and metabolism(Plikus et al.,2015).In fact,the understanding of EMT in cancer development is still limited.In 2015.