Dear Editor,Health management is essential to ensure battery performance and safety, while data-driven learning system is a promising solution to enable efficient state of health(SoH) estimation of lithium-ion(Liion) ...Dear Editor,Health management is essential to ensure battery performance and safety, while data-driven learning system is a promising solution to enable efficient state of health(SoH) estimation of lithium-ion(Liion) batteries. However, the time-consuming signal data acquisition and the lack of interpretability of model still hinder its efficient deployment. Motivated by this, this letter proposes a novel and interpretable data-driven learning strategy through combining the benefits of explainable AI and non-destructive ultrasonic detection for battery SoH estimation. Specifically, after equipping battery with advanced ultrasonic sensor to promise fast real-time ultrasonic signal measurement, an interpretable data-driven learning strategy named generalized additive neural decision ensemble(GANDE) is designed to rapidly estimate battery SoH and explain the effects of the involved ultrasonic features of interest.展开更多
For unachievable tracking problems, where the system output cannot precisely track a given reference, achieving the best possible approximation for the reference trajectory becomes the objective. This study aims to in...For unachievable tracking problems, where the system output cannot precisely track a given reference, achieving the best possible approximation for the reference trajectory becomes the objective. This study aims to investigate solutions using the Ptype learning control scheme. Initially, we demonstrate the necessity of gradient information for achieving the best approximation.Subsequently, we propose an input-output-driven learning gain design to handle the imprecise gradients of a class of uncertain systems. However, it is discovered that the desired performance may not be attainable when faced with incomplete information.To address this issue, an extended iterative learning control scheme is introduced. In this scheme, the tracking errors are modified through output data sampling, which incorporates lowmemory footprints and offers flexibility in learning gain design.The input sequence is shown to converge towards the desired input, resulting in an output that is closest to the given reference in the least square sense. Numerical simulations are provided to validate the theoretical findings.展开更多
The effectiveness of data-driven learning(DDL) has been testified on Chinese learners by using sample corpora of English articles. The result shows that an independent manipulation of the corpora on the part of learne...The effectiveness of data-driven learning(DDL) has been testified on Chinese learners by using sample corpora of English articles. The result shows that an independent manipulation of the corpora on the part of learner can not ensure the suc cess of DDL.展开更多
A case study has been made to explore whether the teacher’s role in data-driven learning(DDL)can be minimized.The outcome shows that the teacher’s role in offering an explicit instruction may be indispensable and ev...A case study has been made to explore whether the teacher’s role in data-driven learning(DDL)can be minimized.The outcome shows that the teacher’s role in offering an explicit instruction may be indispensable and even central to the acquisi tion of English articles.展开更多
BACKGROUND The accurate prediction of lymph node metastasis(LNM)is crucial for managing locally advanced(T3/T4)colorectal cancer(CRC).However,both traditional histopathology and standard slide-level deep learning ofte...BACKGROUND The accurate prediction of lymph node metastasis(LNM)is crucial for managing locally advanced(T3/T4)colorectal cancer(CRC).However,both traditional histopathology and standard slide-level deep learning often fail to capture the sparse and diagnostically critical features of metastatic potential.AIM To develop and validate a case-level multiple-instance learning(MIL)framework mimicking a pathologist's comprehensive review and improve T3/T4 CRC LNM prediction.METHODS The whole-slide images of 130 patients with T3/T4 CRC were retrospectively collected.A case-level MIL framework utilising the CONCH v1.5 and UNI2-h deep learning models was trained on features from all haematoxylin and eosinstained primary tumour slides for each patient.These pathological features were subsequently integrated with clinical data,and model performance was evaluated using the area under the curve(AUC).RESULTS The case-level framework demonstrated superior LNM prediction over slide-level training,with the CONCH v1.5 model achieving a mean AUC(±SD)of 0.899±0.033 vs 0.814±0.083,respectively.Integrating pathology features with clinical data further enhanced performance,yielding a top model with a mean AUC of 0.904±0.047,in sharp contrast to a clinical-only model(mean AUC 0.584±0.084).Crucially,a pathologist’s review confirmed that the model-identified high-attention regions correspond to known high-risk histopathological features.CONCLUSION A case-level MIL framework provides a superior approach for predicting LNM in advanced CRC.This method shows promise for risk stratification and therapy decisions,requiring further validation.展开更多
Background:Stomach cancer(SC)is one of the most lethal malignancies worldwide due to late-stage diagnosis and limited treatment.The transcriptomic,epigenomic,and proteomic,etc.,omics datasets generated by high-through...Background:Stomach cancer(SC)is one of the most lethal malignancies worldwide due to late-stage diagnosis and limited treatment.The transcriptomic,epigenomic,and proteomic,etc.,omics datasets generated by high-throughput sequencing technology have become prominent in biomedical research,and they reveal molecular aspects of cancer diagnosis and therapy.Despite the development of advanced sequencing technology,the presence of high-dimensionality in multi-omics data makes it challenging to interpret the data.Methods:In this study,we introduce RankXLAN,an explainable ensemble-based multi-omics framework that integrates feature selection(FS),ensemble learning,bioinformatics,and in-silico validation for robust biomarker detection,potential therapeutic drug-repurposing candidates’identification,and classification of SC.To enhance the interpretability of the model,we incorporated explainable artificial intelligence(SHapley Additive exPlanations analysis),as well as accuracy,precision,F1-score,recall,cross-validation,specificity,likelihood ratio(LR)+,LR−,and Youden index results.Results:The experimental results showed that the top four FS algorithms achieved improved results when applied to the ensemble learning classification model.The proposed ensemble model produced an area under the curve(AUC)score of 0.994 for gene expression,0.97 for methylation,and 0.96 for miRNA expression data.Through the integration of bioinformatics and ML approach of the transcriptomic and epigenomic multi-omics dataset,we identified potential marker genes,namely,UBE2D2,HPCAL4,IGHA1,DPT,and FN3K.In-silico molecular docking revealed a strong binding affinity between ANKRD13C and the FDA-approved drug Everolimus(binding affinity−10.1 kcal/mol),identifying ANKRD13C as a potential therapeutic drug-repurposing target for SC.Conclusion:The proposed framework RankXLAN outperforms other existing frameworks for serum biomarker identification,therapeutic target identification,and SC classification with multi-omics datasets.展开更多
Wearable sensors integrated with deep learning techniques have the potential to revolutionize seamless human-machine interfaces for real-time health monitoring,clinical diagnosis,and robotic applications.Nevertheless,...Wearable sensors integrated with deep learning techniques have the potential to revolutionize seamless human-machine interfaces for real-time health monitoring,clinical diagnosis,and robotic applications.Nevertheless,it remains a critical challenge to simultaneously achieve desirable mechanical and electrical performance along with biocompatibility,adhesion,self-healing,and environmental robustness with excellent sensing metrics.Herein,we report a multifunctional,anti-freezing,selfadhesive,and self-healable organogel pressure sensor composed of cobalt nanoparticle encapsulated nitrogen-doped carbon nanotubes(CoN CNT)embedded in a polyvinyl alcohol-gelatin(PVA/GLE)matrix.Fabricated using a binary solvent system of water and ethylene glycol(EG),the CoN CNT/PVA/GLE organogel exhibits excellent flexibility,biocompatibility,and temperature tolerance with remarkable environmental stability.Electrochemical impedance spectroscopy confirms near-stable performance across a broad humidity range(40%-95%RH).Freeze-tolerant conductivity under sub-zero conditions(-20℃)is attributed to the synergistic role of CoN CNT and EG,preserving mobility and network integrity.The Co N CNT/PVA/GLE organogel sensor exhibits high sensitivity of 5.75 k Pa^(-1)in the detection range from 0 to 20 k Pa,ideal for subtle biomechanical motion detection.A smart human-machine interface for English letter recognition using deep learning achieved 98%accuracy.The organogel sensor utility was extended to detect human gestures like finger bending,wrist motion,and throat vibration during speech.展开更多
Gastrointestinal(GI)cancers remain a leading cause of cancer-related morbidity and mortality worldwide.Artificial intelligence(AI),particularly machine learning and deep learning(DL),has shown promise in enhancing can...Gastrointestinal(GI)cancers remain a leading cause of cancer-related morbidity and mortality worldwide.Artificial intelligence(AI),particularly machine learning and deep learning(DL),has shown promise in enhancing cancer detection,diagnosis,and prognostication.A narrative review of literature published from January 2015 to march 2025 was conducted using PubMed,Web of Science,and Scopus.Search terms included"gastrointestinal cancer","artificial intelligence","machine learning","deep learning","radiomics","multimodal detection"and"predictive modeling".Studies were included if they focused on clinically relevant AI applications in GI oncology.AI algorithms for GI cancer detection have achieved high performance across imaging modalities,with endoscopic DL systems reporting accuracies of 85%-97%for polyp detection and segmentation.Radiomics-based models have predicted molecular biomarkers such as programmed cell death ligand 2 expression with area under the curves up to 0.92.Large language models applied to radiology reports demonstrated diagnostic accuracy comparable to junior radiologists(78.9%vs 80.0%),though without incremental value when combined with human interpretation.Multimodal AI approaches integrating imaging,pathology,and clinical data show emerging potential for precision oncology.AI in GI oncology has reached clinically relevant accuracy levels in multiple diagnostic tasks,with multimodal approaches and predictive biomarker modeling offering new opportunities for personalized care.However,broader validation,integration into clinical workflows,and attention to ethical,legal,and social implications remain critical for widespread adoption.展开更多
While reinforcement learning-based underwater acoustic adaptive modulation shows promise for enabling environment-adaptive communication as supported by extensive simulation-based research,its practical performance re...While reinforcement learning-based underwater acoustic adaptive modulation shows promise for enabling environment-adaptive communication as supported by extensive simulation-based research,its practical performance remains underexplored in field investigations.To evaluate the practical applicability of this emerging technique in adverse shallow sea channels,a field experiment was conducted using three communication modes:orthogonal frequency division multiplexing(OFDM),M-ary frequency-shift keying(MFSK),and direct sequence spread spectrum(DSSS)for reinforcement learning-driven adaptive modulation.Specifically,a Q-learning method is used to select the optimal modulation mode according to the channel quality quantified by signal-to-noise ratio,multipath spread length,and Doppler frequency offset.Experimental results demonstrate that the reinforcement learning-based adaptive modulation scheme outperformed fixed threshold detection in terms of total throughput and average bit error rate,surpassing conventional adaptive modulation strategies.展开更多
Automated classification of gas flow states in blast furnaces using top-camera imagery typically demands a large volume of labeled data,whose manual annotation is both labor-intensive and cost-prohibitive.To mitigate ...Automated classification of gas flow states in blast furnaces using top-camera imagery typically demands a large volume of labeled data,whose manual annotation is both labor-intensive and cost-prohibitive.To mitigate this challenge,we present an enhanced semi-supervised learning approach based on the Mean Teacher framework,incorporating a novel feature loss module to maximize classification performance with limited labeled samples.The model studies show that the proposed model surpasses both the baseline Mean Teacher model and fully supervised method in accuracy.Specifically,for datasets with 20%,30%,and 40%label ratios,using a single training iteration,the model yields accuracies of 78.61%,82.21%,and 85.2%,respectively,while multiple-cycle training iterations achieves 82.09%,81.97%,and 81.59%,respectively.Furthermore,scenario-specific training schemes are introduced to support diverse deployment need.These findings highlight the potential of the proposed technique in minimizing labeling requirements and advancing intelligent blast furnace diagnostics.展开更多
Deep learning-based methods have become alternatives to traditional numerical weather prediction systems,offering faster computation and the ability to utilize large historical datasets.However,the application of deep...Deep learning-based methods have become alternatives to traditional numerical weather prediction systems,offering faster computation and the ability to utilize large historical datasets.However,the application of deep learning to medium-range regional weather forecasting with limited data remains a significant challenge.In this work,three key solutions are proposed:(1)motivated by the need to improve model performance in data-scarce regional forecasting scenarios,the authors innovatively apply semantic segmentation models,to better capture spatiotemporal features and improve prediction accuracy;(2)recognizing the challenge of overfitting and the inability of traditional noise-based data augmentation methods to effectively enhance model robustness,a novel learnable Gaussian noise mechanism is introduced that allows the model to adaptively optimize perturbations for different locations,ensuring more effective learning;and(3)to address the issue of error accumulation in autoregressive prediction,as well as the challenge of learning difficulty and the lack of intermediate data utilization in one-shot prediction,the authors propose a cascade prediction approach that effectively resolves these problems while significantly improving model forecasting performance.The method achieves a competitive result in The East China Regional AI Medium Range Weather Forecasting Competition.Ablation experiments further validate the effectiveness of each component,highlighting their contributions to enhancing prediction performance.展开更多
Underwater pipeline inspection plays a vital role in the proactive maintenance and management of critical marine infrastructure and subaquatic systems.However,the inspection of underwater pipelines presents a challeng...Underwater pipeline inspection plays a vital role in the proactive maintenance and management of critical marine infrastructure and subaquatic systems.However,the inspection of underwater pipelines presents a challenge due to factors such as light scattering,absorption,restricted visibility,and ambient noise.The advancement of deep learning has introduced powerful techniques for processing large amounts of unstructured and imperfect data collected from underwater environments.This study evaluated the efficacy of the You Only Look Once(YOLO)algorithm,a real-time object detection and localization model based on convolutional neural networks,in identifying and classifying various types of pipeline defects in underwater settings.YOLOv8,the latest evolution in the YOLO family,integrates advanced capabilities,such as anchor-free detection,a cross-stage partial network backbone for efficient feature extraction,and a feature pyramid network+path aggregation network neck for robust multi-scale object detection,which make it particularly well-suited for complex underwater environments.Due to the lack of suitable open-access datasets for underwater pipeline defects,a custom dataset was captured using a remotely operated vehicle in a controlled environment.This application has the following assets available for use.Extensive experimentation demonstrated that YOLOv8 X-Large consistently outperformed other models in terms of pipe defect detection and classification and achieved a strong balance between precision and recall in identifying pipeline cracks,rust,corners,defective welds,flanges,tapes,and holes.This research establishes the baseline performance of YOLOv8 for underwater defect detection and showcases its potential to enhance the reliability and efficiency of pipeline inspection tasks in challenging underwater environments.展开更多
Delayed wound healing following radical gastrectomy remains an important yet underappreciated complication that prolongs hospitalization,increases costs,and undermines patient recovery.In An et al’s recent study,the ...Delayed wound healing following radical gastrectomy remains an important yet underappreciated complication that prolongs hospitalization,increases costs,and undermines patient recovery.In An et al’s recent study,the authors present a machine learning-based risk prediction approach using routinely available clinical and laboratory parameters.Among the evaluated algorithms,a decision tree model demonstrated excellent discrimination,achieving an area under the curve of 0.951 in the validation set and notably identifying all true cases of delayed wound healing at the Youden index threshold.The inclusion of variables such as drainage duration,preoperative white blood cell and neutrophil counts,alongside age and sex,highlights the pragmatic appeal of the model for early postoperative monitoring.Nevertheless,several aspects warrant critical reflection,including the reliance on a postoperative variable(drainage duration),internal validation only,and certain reporting inconsistencies.This letter underscores both the promise and the limitations of adopting interpretable machine learning models in perioperative care.We advocate for transparent reporting,external validation,and careful consideration of clinically actionable timepoints before integration into practice.Ultimately,this work represents a valuable step toward precision risk stratification in gastric cancer surgery,and sets the stage for multicenter,prospective evaluations.展开更多
Oxide dispersion strengthened(ODS)alloys are extensively used owing to high thermostability and creep strength contributed from uniformly dispersed fine oxides particles.However,the existence of these strengthening pa...Oxide dispersion strengthened(ODS)alloys are extensively used owing to high thermostability and creep strength contributed from uniformly dispersed fine oxides particles.However,the existence of these strengthening particles also deteriorates the processability and it is of great importance to establish accurate processing maps to guide the thermomechanical processes to enhance the formability.In this study,we performed particle swarm optimization-based back propagation artificial neural network model to predict the high temperature flow behavior of 0.25wt%Al2O3 particle-reinforced Cu alloys,and compared the accuracy with that of derived by Arrhenius-type constitutive model and back propagation artificial neural network model.To train these models,we obtained the raw data by fabricating ODS Cu alloys using the internal oxidation and reduction method,and conducting systematic hot compression tests between 400 and800℃with strain rates of 10^(-2)-10 S^(-1).At last,processing maps for ODS Cu alloys were proposed by combining processing parameters,mechanical behavior,microstructure characterization,and the modeling results achieved a coefficient of determination higher than>99%.展开更多
An image processing and deep learning method for identifying different types of rock images was proposed.Preprocessing,such as rock image acquisition,gray scaling,Gaussian blurring,and feature dimensionality reduction...An image processing and deep learning method for identifying different types of rock images was proposed.Preprocessing,such as rock image acquisition,gray scaling,Gaussian blurring,and feature dimensionality reduction,was conducted to extract useful feature information and recognize and classify rock images using Tensor Flow-based convolutional neural network(CNN)and Py Qt5.A rock image dataset was established and separated into workouts,confirmation sets,and test sets.The framework was subsequently compiled and trained.The categorization approach was evaluated using image data from the validation and test datasets,and key metrics,such as accuracy,precision,and recall,were analyzed.Finally,the classification model conducted a probabilistic analysis of the measured data to determine the equivalent lithological type for each image.The experimental results indicated that the method combining deep learning,Tensor Flow-based CNN,and Py Qt5 to recognize and classify rock images has an accuracy rate of up to 98.8%,and can be successfully utilized for rock image recognition.The system can be extended to geological exploration,mine engineering,and other rock and mineral resource development to more efficiently and accurately recognize rock samples.Moreover,it can match them with the intelligent support design system to effectively improve the reliability and economy of the support scheme.The system can serve as a reference for supporting the design of other mining and underground space projects.展开更多
The rapid growth of biomedical data,particularly multi-omics data including genomes,transcriptomics,proteomics,metabolomics,and epigenomics,medical research and clinical decision-making confront both new opportunities...The rapid growth of biomedical data,particularly multi-omics data including genomes,transcriptomics,proteomics,metabolomics,and epigenomics,medical research and clinical decision-making confront both new opportunities and obstacles.The huge and diversified nature of these datasets cannot always be managed using traditional data analysis methods.As a consequence,deep learning has emerged as a strong tool for analysing numerous omics data due to its ability to handle complex and non-linear relationships.This paper explores the fundamental concepts of deep learning and how they are used in multi-omics medical data mining.We demonstrate how autoencoders,variational autoencoders,multimodal models,attention mechanisms,transformers,and graph neural networks enable pattern analysis and recognition across all omics data.Deep learning has been found to be effective in illness classification,biomarker identification,gene network learning,and therapeutic efficacy prediction.We also consider critical problems like as data quality,model explainability,whether findings can be repeated,and computational power requirements.We now consider future elements of combining omics with clinical and imaging data,explainable AI,federated learning,and real-time diagnostics.Overall,this study emphasises the need of collaborating across disciplines to advance deep learning-based multi-omics research for precision medicine and comprehending complicated disorders.展开更多
NJmat is a user-friendly,data-driven machine learning interface designed for materials design and analysis.The platform integrates advanced computational techniques,including natural language processing(NLP),large lan...NJmat is a user-friendly,data-driven machine learning interface designed for materials design and analysis.The platform integrates advanced computational techniques,including natural language processing(NLP),large language models(LLM),machine learning potentials(MLP),and graph neural networks(GNN),to facili-tate materials discovery.The platform has been applied in diverse materials research areas,including perovskite surface design,catalyst discovery,battery materials screening,structural alloy design,and molecular informatics.By automating feature selection,predictive modeling,and result interpretation,NJmat accelerates the development of high-performance materials across energy storage,conversion,and structural applications.Additionally,NJmat serves as an educational tool,allowing students and researchers to apply machine learning techniques in materials science with minimal coding expertise.Through automated feature extraction,genetic algorithms,and interpretable machine learning models,NJmat simplifies the workflow for materials informatics,bridging the gap between AI and experimental materials research.The latest version(available at https://figshare.com/articles/software/NJmatML/24607893(accessed on 01 January 2025))enhances its functionality by incorporating NJmatNLP,a module leveraging language models like MatBERT and those based on Word2Vec to support materials prediction tasks.By utilizing clustering and cosine similarity analysis with UMAP visualization,NJmat enables intuitive exploration of materials datasets.While NJmat primarily focuses on structure-property relationships and the discovery of novel chemistries,it can also assist in optimizing processing conditions when relevant parameters are included in the training data.By providing an accessible,integrated environment for machine learning-driven materials discovery,NJmat aligns with the objectives of the Materials Genome Initiative and promotes broader adoption of AI techniques in materials science.展开更多
The Underwater Acoustic(UWA)channel is bandwidth-constrained and experiences doubly selective fading.It is challenging to acquire perfect channel knowledge for Orthogonal Frequency Division Multiplexing(OFDM)communica...The Underwater Acoustic(UWA)channel is bandwidth-constrained and experiences doubly selective fading.It is challenging to acquire perfect channel knowledge for Orthogonal Frequency Division Multiplexing(OFDM)communications using a finite number of pilots.On the other hand,Deep Learning(DL)approaches have been very successful in wireless OFDM communications.However,whether they will work underwater is still a mystery.For the first time,this paper compares two categories of DL-based UWA OFDM receivers:the DataDriven(DD)method,which performs as an end-to-end black box,and the Model-Driven(MD)method,also known as the model-based data-driven method,which combines DL and expert OFDM receiver knowledge.The encoder-decoder framework and Convolutional Neural Network(CNN)structure are employed to establish the DD receiver.On the other hand,an unfolding-based Minimum Mean Square Error(MMSE)structure is adopted for the MD receiver.We analyze the characteristics of different receivers by Monte Carlo simulations under diverse communications conditions and propose a strategy for selecting a proper receiver under different communication scenarios.Field trials in the pool and sea are also conducted to verify the feasibility and advantages of the DL receivers.It is observed that DL receivers perform better than conventional receivers in terms of bit error rate.展开更多
For control systems with unknown model parameters,this paper proposes a data-driven iterative learning method for fault estimation.First,input and output data from the system under fault-free conditions are collected....For control systems with unknown model parameters,this paper proposes a data-driven iterative learning method for fault estimation.First,input and output data from the system under fault-free conditions are collected.By applying orthogonal triangular decomposition and singular value decomposition,a data-driven realization of the system's kernel representation is derived,based on this representation,a residual generator is constructed.Then,the actuator fault signal is estimated online by analyzing the system's dynamic residual,and an iterative learning algorithm is introduced to continuously optimize the residual-based performance function,thereby enhancing estimation accuracy.The proposed method achieves actuator fault estimation without requiring knowledge of model parameters,eliminating the time-consuming system modeling process,and allowing operators to focus on system optimization and decision-making.Compared with existing fault estimation methods,the proposed method demonstrates superior transient performance,steady-state performance,and real-time capability,reduces the need for manual intervention and lowers operational complexity.Finally,experimental results on a mobile robot verify the effectiveness and advantages of the method.展开更多
Post-kidney transplant rejection is a critical factor influencing transplant success rates and the survival of transplanted organs.With the rapid advancement of artificial intelligence technologies,machine learning(ML...Post-kidney transplant rejection is a critical factor influencing transplant success rates and the survival of transplanted organs.With the rapid advancement of artificial intelligence technologies,machine learning(ML)has emerged as a powerful data analysis tool,widely applied in the prediction,diagnosis,and mechanistic study of kidney transplant rejection.This mini-review systematically summarizes the recent applications of ML techniques in post-kidney transplant rejection,covering areas such as the construction of predictive models,identification of biomarkers,analysis of pathological images,assessment of immune cell infiltration,and formulation of personalized treatment strategies.By integrating multi-omics data and clinical information,ML has significantly enhanced the accuracy of early rejection diagnosis and the capability for prognostic evaluation,driving the development of precision medicine in the field of kidney transplantation.Furthermore,this article discusses the challenges faced in existing research and potential future directions,providing a theoretical basis and technical references for related studies.展开更多
基金supported by the National Natural Science Foundation of China(62373224,62333013,U23A20327)the Natural Science Foundation of Shandong Province(ZR2024JQ021)
文摘Dear Editor,Health management is essential to ensure battery performance and safety, while data-driven learning system is a promising solution to enable efficient state of health(SoH) estimation of lithium-ion(Liion) batteries. However, the time-consuming signal data acquisition and the lack of interpretability of model still hinder its efficient deployment. Motivated by this, this letter proposes a novel and interpretable data-driven learning strategy through combining the benefits of explainable AI and non-destructive ultrasonic detection for battery SoH estimation. Specifically, after equipping battery with advanced ultrasonic sensor to promise fast real-time ultrasonic signal measurement, an interpretable data-driven learning strategy named generalized additive neural decision ensemble(GANDE) is designed to rapidly estimate battery SoH and explain the effects of the involved ultrasonic features of interest.
基金supported by the National Natural Science Foundation of China (62173333, 12271522)Beijing Natural Science Foundation (Z210002)the Research Fund of Renmin University of China (2021030187)。
文摘For unachievable tracking problems, where the system output cannot precisely track a given reference, achieving the best possible approximation for the reference trajectory becomes the objective. This study aims to investigate solutions using the Ptype learning control scheme. Initially, we demonstrate the necessity of gradient information for achieving the best approximation.Subsequently, we propose an input-output-driven learning gain design to handle the imprecise gradients of a class of uncertain systems. However, it is discovered that the desired performance may not be attainable when faced with incomplete information.To address this issue, an extended iterative learning control scheme is introduced. In this scheme, the tracking errors are modified through output data sampling, which incorporates lowmemory footprints and offers flexibility in learning gain design.The input sequence is shown to converge towards the desired input, resulting in an output that is closest to the given reference in the least square sense. Numerical simulations are provided to validate the theoretical findings.
文摘The effectiveness of data-driven learning(DDL) has been testified on Chinese learners by using sample corpora of English articles. The result shows that an independent manipulation of the corpora on the part of learner can not ensure the suc cess of DDL.
文摘A case study has been made to explore whether the teacher’s role in data-driven learning(DDL)can be minimized.The outcome shows that the teacher’s role in offering an explicit instruction may be indispensable and even central to the acquisi tion of English articles.
基金Supported by Chongqing Medical Scientific Research Project(Joint Project of Chongqing Health Commission and Science and Technology Bureau),No.2023MSXM060.
文摘BACKGROUND The accurate prediction of lymph node metastasis(LNM)is crucial for managing locally advanced(T3/T4)colorectal cancer(CRC).However,both traditional histopathology and standard slide-level deep learning often fail to capture the sparse and diagnostically critical features of metastatic potential.AIM To develop and validate a case-level multiple-instance learning(MIL)framework mimicking a pathologist's comprehensive review and improve T3/T4 CRC LNM prediction.METHODS The whole-slide images of 130 patients with T3/T4 CRC were retrospectively collected.A case-level MIL framework utilising the CONCH v1.5 and UNI2-h deep learning models was trained on features from all haematoxylin and eosinstained primary tumour slides for each patient.These pathological features were subsequently integrated with clinical data,and model performance was evaluated using the area under the curve(AUC).RESULTS The case-level framework demonstrated superior LNM prediction over slide-level training,with the CONCH v1.5 model achieving a mean AUC(±SD)of 0.899±0.033 vs 0.814±0.083,respectively.Integrating pathology features with clinical data further enhanced performance,yielding a top model with a mean AUC of 0.904±0.047,in sharp contrast to a clinical-only model(mean AUC 0.584±0.084).Crucially,a pathologist’s review confirmed that the model-identified high-attention regions correspond to known high-risk histopathological features.CONCLUSION A case-level MIL framework provides a superior approach for predicting LNM in advanced CRC.This method shows promise for risk stratification and therapy decisions,requiring further validation.
基金the Deanship of Research and Graduate Studies at King Khalid University,KSA,for funding this work through the Large Research Project under grant number RGP2/164/46.
文摘Background:Stomach cancer(SC)is one of the most lethal malignancies worldwide due to late-stage diagnosis and limited treatment.The transcriptomic,epigenomic,and proteomic,etc.,omics datasets generated by high-throughput sequencing technology have become prominent in biomedical research,and they reveal molecular aspects of cancer diagnosis and therapy.Despite the development of advanced sequencing technology,the presence of high-dimensionality in multi-omics data makes it challenging to interpret the data.Methods:In this study,we introduce RankXLAN,an explainable ensemble-based multi-omics framework that integrates feature selection(FS),ensemble learning,bioinformatics,and in-silico validation for robust biomarker detection,potential therapeutic drug-repurposing candidates’identification,and classification of SC.To enhance the interpretability of the model,we incorporated explainable artificial intelligence(SHapley Additive exPlanations analysis),as well as accuracy,precision,F1-score,recall,cross-validation,specificity,likelihood ratio(LR)+,LR−,and Youden index results.Results:The experimental results showed that the top four FS algorithms achieved improved results when applied to the ensemble learning classification model.The proposed ensemble model produced an area under the curve(AUC)score of 0.994 for gene expression,0.97 for methylation,and 0.96 for miRNA expression data.Through the integration of bioinformatics and ML approach of the transcriptomic and epigenomic multi-omics dataset,we identified potential marker genes,namely,UBE2D2,HPCAL4,IGHA1,DPT,and FN3K.In-silico molecular docking revealed a strong binding affinity between ANKRD13C and the FDA-approved drug Everolimus(binding affinity−10.1 kcal/mol),identifying ANKRD13C as a potential therapeutic drug-repurposing target for SC.Conclusion:The proposed framework RankXLAN outperforms other existing frameworks for serum biomarker identification,therapeutic target identification,and SC classification with multi-omics datasets.
基金supported by the Basic Science Research Program(2023R1A2C3004336,RS-202300243807)&Regional Leading Research Center(RS-202400405278)through the National Research Foundation of Korea(NRF)grant funded by the Korea Government(MSIT)。
文摘Wearable sensors integrated with deep learning techniques have the potential to revolutionize seamless human-machine interfaces for real-time health monitoring,clinical diagnosis,and robotic applications.Nevertheless,it remains a critical challenge to simultaneously achieve desirable mechanical and electrical performance along with biocompatibility,adhesion,self-healing,and environmental robustness with excellent sensing metrics.Herein,we report a multifunctional,anti-freezing,selfadhesive,and self-healable organogel pressure sensor composed of cobalt nanoparticle encapsulated nitrogen-doped carbon nanotubes(CoN CNT)embedded in a polyvinyl alcohol-gelatin(PVA/GLE)matrix.Fabricated using a binary solvent system of water and ethylene glycol(EG),the CoN CNT/PVA/GLE organogel exhibits excellent flexibility,biocompatibility,and temperature tolerance with remarkable environmental stability.Electrochemical impedance spectroscopy confirms near-stable performance across a broad humidity range(40%-95%RH).Freeze-tolerant conductivity under sub-zero conditions(-20℃)is attributed to the synergistic role of CoN CNT and EG,preserving mobility and network integrity.The Co N CNT/PVA/GLE organogel sensor exhibits high sensitivity of 5.75 k Pa^(-1)in the detection range from 0 to 20 k Pa,ideal for subtle biomechanical motion detection.A smart human-machine interface for English letter recognition using deep learning achieved 98%accuracy.The organogel sensor utility was extended to detect human gestures like finger bending,wrist motion,and throat vibration during speech.
文摘Gastrointestinal(GI)cancers remain a leading cause of cancer-related morbidity and mortality worldwide.Artificial intelligence(AI),particularly machine learning and deep learning(DL),has shown promise in enhancing cancer detection,diagnosis,and prognostication.A narrative review of literature published from January 2015 to march 2025 was conducted using PubMed,Web of Science,and Scopus.Search terms included"gastrointestinal cancer","artificial intelligence","machine learning","deep learning","radiomics","multimodal detection"and"predictive modeling".Studies were included if they focused on clinically relevant AI applications in GI oncology.AI algorithms for GI cancer detection have achieved high performance across imaging modalities,with endoscopic DL systems reporting accuracies of 85%-97%for polyp detection and segmentation.Radiomics-based models have predicted molecular biomarkers such as programmed cell death ligand 2 expression with area under the curves up to 0.92.Large language models applied to radiology reports demonstrated diagnostic accuracy comparable to junior radiologists(78.9%vs 80.0%),though without incremental value when combined with human interpretation.Multimodal AI approaches integrating imaging,pathology,and clinical data show emerging potential for precision oncology.AI in GI oncology has reached clinically relevant accuracy levels in multiple diagnostic tasks,with multimodal approaches and predictive biomarker modeling offering new opportunities for personalized care.However,broader validation,integration into clinical workflows,and attention to ethical,legal,and social implications remain critical for widespread adoption.
基金funding from the National Key Research and Development Program of China(No.2018YFE0110000)the National Natural Science Foundation of China(No.11274259,No.11574258)the Science and Technology Commission Foundation of Shanghai(21DZ1205500)in support of the present research.
文摘While reinforcement learning-based underwater acoustic adaptive modulation shows promise for enabling environment-adaptive communication as supported by extensive simulation-based research,its practical performance remains underexplored in field investigations.To evaluate the practical applicability of this emerging technique in adverse shallow sea channels,a field experiment was conducted using three communication modes:orthogonal frequency division multiplexing(OFDM),M-ary frequency-shift keying(MFSK),and direct sequence spread spectrum(DSSS)for reinforcement learning-driven adaptive modulation.Specifically,a Q-learning method is used to select the optimal modulation mode according to the channel quality quantified by signal-to-noise ratio,multipath spread length,and Doppler frequency offset.Experimental results demonstrate that the reinforcement learning-based adaptive modulation scheme outperformed fixed threshold detection in terms of total throughput and average bit error rate,surpassing conventional adaptive modulation strategies.
基金financial support provided by the Natural Science Foundation of Hebei Province,China(No.E2024105036)the Tangshan Talent Funding Project,China(Nos.B202302007 and A2021110015)+1 种基金the National Natural Science Foundation of China(No.52264042)the Australian Research Council(No.IH230100010)。
文摘Automated classification of gas flow states in blast furnaces using top-camera imagery typically demands a large volume of labeled data,whose manual annotation is both labor-intensive and cost-prohibitive.To mitigate this challenge,we present an enhanced semi-supervised learning approach based on the Mean Teacher framework,incorporating a novel feature loss module to maximize classification performance with limited labeled samples.The model studies show that the proposed model surpasses both the baseline Mean Teacher model and fully supervised method in accuracy.Specifically,for datasets with 20%,30%,and 40%label ratios,using a single training iteration,the model yields accuracies of 78.61%,82.21%,and 85.2%,respectively,while multiple-cycle training iterations achieves 82.09%,81.97%,and 81.59%,respectively.Furthermore,scenario-specific training schemes are introduced to support diverse deployment need.These findings highlight the potential of the proposed technique in minimizing labeling requirements and advancing intelligent blast furnace diagnostics.
基金supported by the National Natural Science Foundation of China[grant number 62376217]the Young Elite Scientists Sponsorship Program by CAST[grant number 2023QNRC001]the Joint Research Project for Meteorological Capacity Improvement[grant number 24NLTSZ003]。
文摘Deep learning-based methods have become alternatives to traditional numerical weather prediction systems,offering faster computation and the ability to utilize large historical datasets.However,the application of deep learning to medium-range regional weather forecasting with limited data remains a significant challenge.In this work,three key solutions are proposed:(1)motivated by the need to improve model performance in data-scarce regional forecasting scenarios,the authors innovatively apply semantic segmentation models,to better capture spatiotemporal features and improve prediction accuracy;(2)recognizing the challenge of overfitting and the inability of traditional noise-based data augmentation methods to effectively enhance model robustness,a novel learnable Gaussian noise mechanism is introduced that allows the model to adaptively optimize perturbations for different locations,ensuring more effective learning;and(3)to address the issue of error accumulation in autoregressive prediction,as well as the challenge of learning difficulty and the lack of intermediate data utilization in one-shot prediction,the authors propose a cascade prediction approach that effectively resolves these problems while significantly improving model forecasting performance.The method achieves a competitive result in The East China Regional AI Medium Range Weather Forecasting Competition.Ablation experiments further validate the effectiveness of each component,highlighting their contributions to enhancing prediction performance.
文摘Underwater pipeline inspection plays a vital role in the proactive maintenance and management of critical marine infrastructure and subaquatic systems.However,the inspection of underwater pipelines presents a challenge due to factors such as light scattering,absorption,restricted visibility,and ambient noise.The advancement of deep learning has introduced powerful techniques for processing large amounts of unstructured and imperfect data collected from underwater environments.This study evaluated the efficacy of the You Only Look Once(YOLO)algorithm,a real-time object detection and localization model based on convolutional neural networks,in identifying and classifying various types of pipeline defects in underwater settings.YOLOv8,the latest evolution in the YOLO family,integrates advanced capabilities,such as anchor-free detection,a cross-stage partial network backbone for efficient feature extraction,and a feature pyramid network+path aggregation network neck for robust multi-scale object detection,which make it particularly well-suited for complex underwater environments.Due to the lack of suitable open-access datasets for underwater pipeline defects,a custom dataset was captured using a remotely operated vehicle in a controlled environment.This application has the following assets available for use.Extensive experimentation demonstrated that YOLOv8 X-Large consistently outperformed other models in terms of pipe defect detection and classification and achieved a strong balance between precision and recall in identifying pipeline cracks,rust,corners,defective welds,flanges,tapes,and holes.This research establishes the baseline performance of YOLOv8 for underwater defect detection and showcases its potential to enhance the reliability and efficiency of pipeline inspection tasks in challenging underwater environments.
文摘Delayed wound healing following radical gastrectomy remains an important yet underappreciated complication that prolongs hospitalization,increases costs,and undermines patient recovery.In An et al’s recent study,the authors present a machine learning-based risk prediction approach using routinely available clinical and laboratory parameters.Among the evaluated algorithms,a decision tree model demonstrated excellent discrimination,achieving an area under the curve of 0.951 in the validation set and notably identifying all true cases of delayed wound healing at the Youden index threshold.The inclusion of variables such as drainage duration,preoperative white blood cell and neutrophil counts,alongside age and sex,highlights the pragmatic appeal of the model for early postoperative monitoring.Nevertheless,several aspects warrant critical reflection,including the reliance on a postoperative variable(drainage duration),internal validation only,and certain reporting inconsistencies.This letter underscores both the promise and the limitations of adopting interpretable machine learning models in perioperative care.We advocate for transparent reporting,external validation,and careful consideration of clinically actionable timepoints before integration into practice.Ultimately,this work represents a valuable step toward precision risk stratification in gastric cancer surgery,and sets the stage for multicenter,prospective evaluations.
基金financial support of the National Natural Science Foundation of China(No.52371103)the Fundamental Research Funds for the Central Universities,China(No.2242023K40028)+1 种基金the Open Research Fund of Jiangsu Key Laboratory for Advanced Metallic Materials,China(No.AMM2023B01).financial support of the Research Fund of Shihezi Key Laboratory of AluminumBased Advanced Materials,China(No.2023PT02)financial support of Guangdong Province Science and Technology Major Project,China(No.2021B0301030005)。
文摘Oxide dispersion strengthened(ODS)alloys are extensively used owing to high thermostability and creep strength contributed from uniformly dispersed fine oxides particles.However,the existence of these strengthening particles also deteriorates the processability and it is of great importance to establish accurate processing maps to guide the thermomechanical processes to enhance the formability.In this study,we performed particle swarm optimization-based back propagation artificial neural network model to predict the high temperature flow behavior of 0.25wt%Al2O3 particle-reinforced Cu alloys,and compared the accuracy with that of derived by Arrhenius-type constitutive model and back propagation artificial neural network model.To train these models,we obtained the raw data by fabricating ODS Cu alloys using the internal oxidation and reduction method,and conducting systematic hot compression tests between 400 and800℃with strain rates of 10^(-2)-10 S^(-1).At last,processing maps for ODS Cu alloys were proposed by combining processing parameters,mechanical behavior,microstructure characterization,and the modeling results achieved a coefficient of determination higher than>99%.
基金financially supported by the National Science and Technology Major Project——Deep Earth Probe and Mineral Resources Exploration(No.2024ZD1003701)the National Key R&D Program of China(No.2022YFC2905004)。
文摘An image processing and deep learning method for identifying different types of rock images was proposed.Preprocessing,such as rock image acquisition,gray scaling,Gaussian blurring,and feature dimensionality reduction,was conducted to extract useful feature information and recognize and classify rock images using Tensor Flow-based convolutional neural network(CNN)and Py Qt5.A rock image dataset was established and separated into workouts,confirmation sets,and test sets.The framework was subsequently compiled and trained.The categorization approach was evaluated using image data from the validation and test datasets,and key metrics,such as accuracy,precision,and recall,were analyzed.Finally,the classification model conducted a probabilistic analysis of the measured data to determine the equivalent lithological type for each image.The experimental results indicated that the method combining deep learning,Tensor Flow-based CNN,and Py Qt5 to recognize and classify rock images has an accuracy rate of up to 98.8%,and can be successfully utilized for rock image recognition.The system can be extended to geological exploration,mine engineering,and other rock and mineral resource development to more efficiently and accurately recognize rock samples.Moreover,it can match them with the intelligent support design system to effectively improve the reliability and economy of the support scheme.The system can serve as a reference for supporting the design of other mining and underground space projects.
文摘The rapid growth of biomedical data,particularly multi-omics data including genomes,transcriptomics,proteomics,metabolomics,and epigenomics,medical research and clinical decision-making confront both new opportunities and obstacles.The huge and diversified nature of these datasets cannot always be managed using traditional data analysis methods.As a consequence,deep learning has emerged as a strong tool for analysing numerous omics data due to its ability to handle complex and non-linear relationships.This paper explores the fundamental concepts of deep learning and how they are used in multi-omics medical data mining.We demonstrate how autoencoders,variational autoencoders,multimodal models,attention mechanisms,transformers,and graph neural networks enable pattern analysis and recognition across all omics data.Deep learning has been found to be effective in illness classification,biomarker identification,gene network learning,and therapeutic efficacy prediction.We also consider critical problems like as data quality,model explainability,whether findings can be repeated,and computational power requirements.We now consider future elements of combining omics with clinical and imaging data,explainable AI,federated learning,and real-time diagnostics.Overall,this study emphasises the need of collaborating across disciplines to advance deep learning-based multi-omics research for precision medicine and comprehending complicated disorders.
基金supported by the Jiangsu Provincial Science and Technology Project Basic Research Program(Natural Science Foundation of Jiangsu Province)(No.BK20211283).
文摘NJmat is a user-friendly,data-driven machine learning interface designed for materials design and analysis.The platform integrates advanced computational techniques,including natural language processing(NLP),large language models(LLM),machine learning potentials(MLP),and graph neural networks(GNN),to facili-tate materials discovery.The platform has been applied in diverse materials research areas,including perovskite surface design,catalyst discovery,battery materials screening,structural alloy design,and molecular informatics.By automating feature selection,predictive modeling,and result interpretation,NJmat accelerates the development of high-performance materials across energy storage,conversion,and structural applications.Additionally,NJmat serves as an educational tool,allowing students and researchers to apply machine learning techniques in materials science with minimal coding expertise.Through automated feature extraction,genetic algorithms,and interpretable machine learning models,NJmat simplifies the workflow for materials informatics,bridging the gap between AI and experimental materials research.The latest version(available at https://figshare.com/articles/software/NJmatML/24607893(accessed on 01 January 2025))enhances its functionality by incorporating NJmatNLP,a module leveraging language models like MatBERT and those based on Word2Vec to support materials prediction tasks.By utilizing clustering and cosine similarity analysis with UMAP visualization,NJmat enables intuitive exploration of materials datasets.While NJmat primarily focuses on structure-property relationships and the discovery of novel chemistries,it can also assist in optimizing processing conditions when relevant parameters are included in the training data.By providing an accessible,integrated environment for machine learning-driven materials discovery,NJmat aligns with the objectives of the Materials Genome Initiative and promotes broader adoption of AI techniques in materials science.
基金funded in part by the National Natural Science Foundation of China under Grant 62401167 and 62192712in part by the Key Laboratory of Marine Environmental Survey Technology and Application,Ministry of Natural Resources,P.R.China under Grant MESTA-2023-B001in part by the Stable Supporting Fund of National Key Laboratory of Underwater Acoustic Technology under Grant JCKYS2022604SSJS007.
文摘The Underwater Acoustic(UWA)channel is bandwidth-constrained and experiences doubly selective fading.It is challenging to acquire perfect channel knowledge for Orthogonal Frequency Division Multiplexing(OFDM)communications using a finite number of pilots.On the other hand,Deep Learning(DL)approaches have been very successful in wireless OFDM communications.However,whether they will work underwater is still a mystery.For the first time,this paper compares two categories of DL-based UWA OFDM receivers:the DataDriven(DD)method,which performs as an end-to-end black box,and the Model-Driven(MD)method,also known as the model-based data-driven method,which combines DL and expert OFDM receiver knowledge.The encoder-decoder framework and Convolutional Neural Network(CNN)structure are employed to establish the DD receiver.On the other hand,an unfolding-based Minimum Mean Square Error(MMSE)structure is adopted for the MD receiver.We analyze the characteristics of different receivers by Monte Carlo simulations under diverse communications conditions and propose a strategy for selecting a proper receiver under different communication scenarios.Field trials in the pool and sea are also conducted to verify the feasibility and advantages of the DL receivers.It is observed that DL receivers perform better than conventional receivers in terms of bit error rate.
基金Supported by Shandong Provincial Taishan Scholar Program(Grant No.tsqn202312133)Shandong Provincial Natural Science Foundation(Grant Nos.ZR2022YQ61,ZR2023ZD32)+1 种基金Shandong Provincial Natural Science Foundation(Grant No.ZR2023ZD32)National Natural Science Foundation of China(Grant Nos.61772551 and 62111530052)。
文摘For control systems with unknown model parameters,this paper proposes a data-driven iterative learning method for fault estimation.First,input and output data from the system under fault-free conditions are collected.By applying orthogonal triangular decomposition and singular value decomposition,a data-driven realization of the system's kernel representation is derived,based on this representation,a residual generator is constructed.Then,the actuator fault signal is estimated online by analyzing the system's dynamic residual,and an iterative learning algorithm is introduced to continuously optimize the residual-based performance function,thereby enhancing estimation accuracy.The proposed method achieves actuator fault estimation without requiring knowledge of model parameters,eliminating the time-consuming system modeling process,and allowing operators to focus on system optimization and decision-making.Compared with existing fault estimation methods,the proposed method demonstrates superior transient performance,steady-state performance,and real-time capability,reduces the need for manual intervention and lowers operational complexity.Finally,experimental results on a mobile robot verify the effectiveness and advantages of the method.
文摘Post-kidney transplant rejection is a critical factor influencing transplant success rates and the survival of transplanted organs.With the rapid advancement of artificial intelligence technologies,machine learning(ML)has emerged as a powerful data analysis tool,widely applied in the prediction,diagnosis,and mechanistic study of kidney transplant rejection.This mini-review systematically summarizes the recent applications of ML techniques in post-kidney transplant rejection,covering areas such as the construction of predictive models,identification of biomarkers,analysis of pathological images,assessment of immune cell infiltration,and formulation of personalized treatment strategies.By integrating multi-omics data and clinical information,ML has significantly enhanced the accuracy of early rejection diagnosis and the capability for prognostic evaluation,driving the development of precision medicine in the field of kidney transplantation.Furthermore,this article discusses the challenges faced in existing research and potential future directions,providing a theoretical basis and technical references for related studies.
