With the continuous advancement of the tiered diagnosis and treatment system,the medical consortium model has gained increasing attention as an important approach to promoting the vertical integration of healthcare re...With the continuous advancement of the tiered diagnosis and treatment system,the medical consortium model has gained increasing attention as an important approach to promoting the vertical integration of healthcare resources.Within this context,laboratory data,as a key component of healthcare information systems,urgently requires efficient sharing and intelligent analysis.This paper designs and constructs an intelligent early warning system for laboratory data based on a cloud platform tailored to the medical consortium model.Through standardized data formats and unified access interfaces,the system enables the integration and cleaning of laboratory data across multiple healthcare institutions.By combining medical rule sets with machine learning models,the system achieves graded alerts and rapid responses to abnormal key indicators and potential outbreaks of infectious diseases.Practical deployment results demonstrate that the system significantly improves the utilization efficiency of laboratory data,strengthens public health event monitoring,and optimizes inter-institutional collaboration.The paper also discusses challenges encountered during system implementation,such as inconsistent data standards,security and compliance concerns,and model interpretability,and proposes corresponding optimization strategies.These findings provide a reference for the broader application of intelligent medical early warning systems.展开更多
Standardized datasets are foundational to healthcare informatization by enhancing data quality and unleashing the value of data elements.Using bibliometrics and content analysis,this study examines China's healthc...Standardized datasets are foundational to healthcare informatization by enhancing data quality and unleashing the value of data elements.Using bibliometrics and content analysis,this study examines China's healthcare dataset standards from 2011 to 2025.It analyzes their evolution across types,applications,institutions,and themes,highlighting key achievements including substantial growth in quantity,optimized typology,expansion into innovative application scenarios such as health decision support,and broadened institutional involvement.The study also identifies critical challenges,including imbalanced development,insufficient quality control,and a lack of essential metadata—such as authoritative data element mappings and privacy annotations—which hampers the delivery of intelligent services.To address these challenges,the study proposes a multi-faceted strategy focused on optimizing the standard system's architecture,enhancing quality and implementation,and advancing both data governance—through authoritative tracing and privacy protection—and intelligent service provision.These strategies aim to promote the application of dataset standards,thereby fostering and securing the development of new productive forces in healthcare.展开更多
Progress in developing robust therapies for spinal cord injury （SCI）, trau- matic brain injury （TBI） and peripheral nerve injury has been slow. A great deal has been learned over the past 30 years regarding both t...Progress in developing robust therapies for spinal cord injury （SCI）, trau- matic brain injury （TBI） and peripheral nerve injury has been slow. A great deal has been learned over the past 30 years regarding both the intrinsic factors and the environmental factors that regulate axon growth, but this large body of information has not yet resulted in clinically available thera- peutics. This therapeutic bottleneck has many root causes, but a consensus is emerging that one contributing factor is a lack of standards for experi- mental design and reporting. The absence of reporting standards, and even of commonly accepted definitions of key words, also make data mining and bioinformatics analysis of neural plasticity and regeneration difficult, if not impossible. This short review will consider relevant background and poten- tial solutions to this problem in the axon regeneration domain.展开更多
Commentary Most would agree that providing comprehensive detail in scientific reporting is critical for the development of mean- ingful therapies and treatments for diseases. Such stellar practices 1） allow for repro...Commentary Most would agree that providing comprehensive detail in scientific reporting is critical for the development of mean- ingful therapies and treatments for diseases. Such stellar practices 1） allow for reproduction of experiments to con- firm results, 2） promote thorough analyses of data, and 3） foster the incremental advancement of valid approaches. Unfortunately, most would also agree we have far to go to reach this vital goal （Hackam and Redelmeier, 2006; Prinz et al., 2011; Baker et al., 2014）.展开更多
Viral infectious diseases,characterized by their intricate nature and wide-ranging diversity,pose substantial challenges in the domain of data management.The vast volume of data generated by these diseases,spanning fr...Viral infectious diseases,characterized by their intricate nature and wide-ranging diversity,pose substantial challenges in the domain of data management.The vast volume of data generated by these diseases,spanning from the molecular mechanisms within cells to large-scale epidemiological patterns,has surpassed the capabilities of traditional analytical methods.In the era of artificial intelligence(AI)and big data,there is an urgent necessity for the optimization of these analytical methods to more effectively handle and utilize the information.Despite the rapid accumulation of data associated with viral infections,the lack of a comprehensive framework for integrating,selecting,and analyzing these datasets has left numerous researchers uncertain about which data to select,how to access it,and how to utilize it most effectively in their research.This review endeavors to fill these gaps by exploring the multifaceted nature of viral infectious diseases and summarizing relevant data across multiple levels,from the molecular details of pathogens to broad epidemiological trends.The scope extends from the micro-scale to the macro-scale,encompassing pathogens,hosts,and vectors.In addition to data summarization,this review thoroughly investigates various dataset sources.It also traces the historical evolution of data collection in the field of viral infectious diseases,highlighting the progress achieved over time.Simultaneously,it evaluates the current limitations that impede data utilization.Furthermore,we propose strategies to surmount these challenges,focusing on the development and application of advanced computational techniques,AI-driven models,and enhanced data integration practices.By providing a comprehensive synthesis of existing knowledge,this review is designed to guide future research and contribute to more informed approaches in the surveillance,prevention,and control of viral infectious diseases,particularly within the context of the expanding big-data landscape.展开更多
1.1. Development of international data exchange standards in securities field Securities market involves a large number of participants, like investors, securities companies, exchanges, clearingcorporations and so on...1.1. Development of international data exchange standards in securities field Securities market involves a large number of participants, like investors, securities companies, exchanges, clearingcorporations and so on. Businesses among the participants are completed via data exchange. Therefore, the data exchange protocols serve an important factor to determine and promote the sate and rapid development of the securities market.展开更多
The geometrical and topological information of 3D computer aided design （CAD） models should be represented as a neut- ral format file to exchange the data between different CAD systems. Exchange of 3D CAD model data...The geometrical and topological information of 3D computer aided design （CAD） models should be represented as a neut- ral format file to exchange the data between different CAD systems. Exchange of 3D CAD model data implies that the companies must exchange complete information about their products, all the way from design, manufacturing to inspection and shipping. This informa- tion should be available to each relevant partner over the entire life cycle of the product. This led to the development of an international standard organization （ISO） neutral format file named as standard for the exchange of product model data （STEP）. It has been ob- served from the literature, the feature recognition systems developed were identified as planar, cylindrical, conical and to some extent spherical and toroidal surfaces. The advanced surface features such as B-spline and its subtypes are not identified. Therefore, in this work, a STEP-based feature recognition system is developed to recognize t--spline surface features and its sub-types from the 3D CAD model represented in AP203 neutral file format. The developed feature recognition system is implemented in Java programming language and the product model data represented in STEP AP203 format is interpreted through Java standard data access interface （JSDAI）. The developed system could recognize B-spline surface features such as B-Spline surface with knots, quasi uniform surface, uniform surface, rational surface and Bezier surface. The application of extracted B-spline surface features information is discussed with reference to the toolpath generation for STEP-NC （STEP AP238）.展开更多
In the course of network supported collaborative design,the data processing plays a very vital role.Much effort has been spent in this area,and many kinds of approaches have been proposed.Based on the correlative mate...In the course of network supported collaborative design,the data processing plays a very vital role.Much effort has been spent in this area,and many kinds of approaches have been proposed.Based on the correlative materials,this paper presents extensible markup language(XML)based strategy for several important problems of data processing in network supported collaborative design,such as the representation of standard for the exchange of product model data(STEP)with XML in the product information expression and the management of XML documents using relational database.The paper gives a detailed exposition on how to clarify the mapping between XML structure and the relationship database structure and how XML-QL queries can be translated into structured query language(SQL)queries.Finally,the structure of data processing system based on XML is presented.展开更多
The paper mainly discusses the integrity of the forwarded subscription message guaranteed by secure channel which encrypted in data communication by using data encryption standard （DES） algorithm and chaos code algo...The paper mainly discusses the integrity of the forwarded subscription message guaranteed by secure channel which encrypted in data communication by using data encryption standard （DES） algorithm and chaos code algorithm between broker nodes in the routing process of the contentbased publish/subscribe system. It analyzes the security of the secure channel encrypted with data communication by DES algorithm and chaos code algorithm, and finds out the secure channel can be easily attacked by known plain text. Therefore, the paper proposes the improved algorithm of message encryption and authentication, combining encryption and the generation of the message authentication code together to finish scanning at one time, which enhances both the secure degree and running efficiency. This secure channel system has a certain reference value to the pub/sub system requiring highly communication security.展开更多
To make inorganic structure data more useful for further studies a five-point list of simple procedures to be followed by authors of crystal structure papers is proposed. 1. A crystal structure should be described wit...To make inorganic structure data more useful for further studies a five-point list of simple procedures to be followed by authors of crystal structure papers is proposed. 1. A crystal structure should be described with the space group corresponding to its true symmetry. 2. A new structure proposal should be tested, if it is realistic in principle. 3. A structure should be described with a space group in a setting given in the International Tables. 4. For a comparison with other structures the structure data should be standardized with the program STRUCTURE TIDY. 5. 揘ew?structure data should be checked in the databases, Chemical Abstracts or on-line internet resources, if they are really new. The list is supplemented with many explanations, commentaries, examples and references.展开更多
文摘With the continuous advancement of the tiered diagnosis and treatment system,the medical consortium model has gained increasing attention as an important approach to promoting the vertical integration of healthcare resources.Within this context,laboratory data,as a key component of healthcare information systems,urgently requires efficient sharing and intelligent analysis.This paper designs and constructs an intelligent early warning system for laboratory data based on a cloud platform tailored to the medical consortium model.Through standardized data formats and unified access interfaces,the system enables the integration and cleaning of laboratory data across multiple healthcare institutions.By combining medical rule sets with machine learning models,the system achieves graded alerts and rapid responses to abnormal key indicators and potential outbreaks of infectious diseases.Practical deployment results demonstrate that the system significantly improves the utilization efficiency of laboratory data,strengthens public health event monitoring,and optimizes inter-institutional collaboration.The paper also discusses challenges encountered during system implementation,such as inconsistent data standards,security and compliance concerns,and model interpretability,and proposes corresponding optimization strategies.These findings provide a reference for the broader application of intelligent medical early warning systems.
文摘Standardized datasets are foundational to healthcare informatization by enhancing data quality and unleashing the value of data elements.Using bibliometrics and content analysis,this study examines China's healthcare dataset standards from 2011 to 2025.It analyzes their evolution across types,applications,institutions,and themes,highlighting key achievements including substantial growth in quantity,optimized typology,expansion into innovative application scenarios such as health decision support,and broadened institutional involvement.The study also identifies critical challenges,including imbalanced development,insufficient quality control,and a lack of essential metadata—such as authoritative data element mappings and privacy annotations—which hampers the delivery of intelligent services.To address these challenges,the study proposes a multi-faceted strategy focused on optimizing the standard system's architecture,enhancing quality and implementation,and advancing both data governance—through authoritative tracing and privacy protection—and intelligent service provision.These strategies aim to promote the application of dataset standards,thereby fostering and securing the development of new productive forces in healthcare.
基金Research in the Lemmon/Bixby lab is supported by NIH grants NS080145 and NS059866by the Miami Project to Cure Paralysis
文摘Progress in developing robust therapies for spinal cord injury （SCI）, trau- matic brain injury （TBI） and peripheral nerve injury has been slow. A great deal has been learned over the past 30 years regarding both the intrinsic factors and the environmental factors that regulate axon growth, but this large body of information has not yet resulted in clinically available thera- peutics. This therapeutic bottleneck has many root causes, but a consensus is emerging that one contributing factor is a lack of standards for experi- mental design and reporting. The absence of reporting standards, and even of commonly accepted definitions of key words, also make data mining and bioinformatics analysis of neural plasticity and regeneration difficult, if not impossible. This short review will consider relevant background and poten- tial solutions to this problem in the axon regeneration domain.
文摘Commentary Most would agree that providing comprehensive detail in scientific reporting is critical for the development of mean- ingful therapies and treatments for diseases. Such stellar practices 1） allow for reproduction of experiments to con- firm results, 2） promote thorough analyses of data, and 3） foster the incremental advancement of valid approaches. Unfortunately, most would also agree we have far to go to reach this vital goal （Hackam and Redelmeier, 2006; Prinz et al., 2011; Baker et al., 2014）.
基金supported by the National Natural Science Foundation of China(32370703)the CAMS Innovation Fund for Medical Sciences(CIFMS)(2022-I2M-1-021,2021-I2M-1-061)the Major Project of Guangzhou National Labora-tory(GZNL2024A01015).
文摘Viral infectious diseases,characterized by their intricate nature and wide-ranging diversity,pose substantial challenges in the domain of data management.The vast volume of data generated by these diseases,spanning from the molecular mechanisms within cells to large-scale epidemiological patterns,has surpassed the capabilities of traditional analytical methods.In the era of artificial intelligence(AI)and big data,there is an urgent necessity for the optimization of these analytical methods to more effectively handle and utilize the information.Despite the rapid accumulation of data associated with viral infections,the lack of a comprehensive framework for integrating,selecting,and analyzing these datasets has left numerous researchers uncertain about which data to select,how to access it,and how to utilize it most effectively in their research.This review endeavors to fill these gaps by exploring the multifaceted nature of viral infectious diseases and summarizing relevant data across multiple levels,from the molecular details of pathogens to broad epidemiological trends.The scope extends from the micro-scale to the macro-scale,encompassing pathogens,hosts,and vectors.In addition to data summarization,this review thoroughly investigates various dataset sources.It also traces the historical evolution of data collection in the field of viral infectious diseases,highlighting the progress achieved over time.Simultaneously,it evaluates the current limitations that impede data utilization.Furthermore,we propose strategies to surmount these challenges,focusing on the development and application of advanced computational techniques,AI-driven models,and enhanced data integration practices.By providing a comprehensive synthesis of existing knowledge,this review is designed to guide future research and contribute to more informed approaches in the surveillance,prevention,and control of viral infectious diseases,particularly within the context of the expanding big-data landscape.
文摘1.1. Development of international data exchange standards in securities field Securities market involves a large number of participants, like investors, securities companies, exchanges, clearingcorporations and so on. Businesses among the participants are completed via data exchange. Therefore, the data exchange protocols serve an important factor to determine and promote the sate and rapid development of the securities market.
文摘The geometrical and topological information of 3D computer aided design （CAD） models should be represented as a neut- ral format file to exchange the data between different CAD systems. Exchange of 3D CAD model data implies that the companies must exchange complete information about their products, all the way from design, manufacturing to inspection and shipping. This informa- tion should be available to each relevant partner over the entire life cycle of the product. This led to the development of an international standard organization （ISO） neutral format file named as standard for the exchange of product model data （STEP）. It has been ob- served from the literature, the feature recognition systems developed were identified as planar, cylindrical, conical and to some extent spherical and toroidal surfaces. The advanced surface features such as B-spline and its subtypes are not identified. Therefore, in this work, a STEP-based feature recognition system is developed to recognize t--spline surface features and its sub-types from the 3D CAD model represented in AP203 neutral file format. The developed feature recognition system is implemented in Java programming language and the product model data represented in STEP AP203 format is interpreted through Java standard data access interface （JSDAI）. The developed system could recognize B-spline surface features such as B-Spline surface with knots, quasi uniform surface, uniform surface, rational surface and Bezier surface. The application of extracted B-spline surface features information is discussed with reference to the toolpath generation for STEP-NC （STEP AP238）.
基金supported by National High Technology Research and Development Program of China(863 Program)(No.AA420060)
文摘In the course of network supported collaborative design,the data processing plays a very vital role.Much effort has been spent in this area,and many kinds of approaches have been proposed.Based on the correlative materials,this paper presents extensible markup language(XML)based strategy for several important problems of data processing in network supported collaborative design,such as the representation of standard for the exchange of product model data(STEP)with XML in the product information expression and the management of XML documents using relational database.The paper gives a detailed exposition on how to clarify the mapping between XML structure and the relationship database structure and how XML-QL queries can be translated into structured query language(SQL)queries.Finally,the structure of data processing system based on XML is presented.
基金Supported by the National Natural Science Foun-dation of China (60273014)
文摘The paper mainly discusses the integrity of the forwarded subscription message guaranteed by secure channel which encrypted in data communication by using data encryption standard （DES） algorithm and chaos code algorithm between broker nodes in the routing process of the contentbased publish/subscribe system. It analyzes the security of the secure channel encrypted with data communication by DES algorithm and chaos code algorithm, and finds out the secure channel can be easily attacked by known plain text. Therefore, the paper proposes the improved algorithm of message encryption and authentication, combining encryption and the generation of the message authentication code together to finish scanning at one time, which enhances both the secure degree and running efficiency. This secure channel system has a certain reference value to the pub/sub system requiring highly communication security.
文摘To make inorganic structure data more useful for further studies a five-point list of simple procedures to be followed by authors of crystal structure papers is proposed. 1. A crystal structure should be described with the space group corresponding to its true symmetry. 2. A new structure proposal should be tested, if it is realistic in principle. 3. A structure should be described with a space group in a setting given in the International Tables. 4. For a comparison with other structures the structure data should be standardized with the program STRUCTURE TIDY. 5. 揘ew?structure data should be checked in the databases, Chemical Abstracts or on-line internet resources, if they are really new. The list is supplemented with many explanations, commentaries, examples and references.
