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Approach for redefining the damping factor of railway bridges with ballast superstructure:model calibration and guidelines for practical application
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作者 Andreas Stollwitzer Samuel Loidl +1 位作者 Lara Bettinelli Josef Fink 《Railway Engineering Science》 2026年第1期97-127,共31页
To ensure the compatibility between rolling stock and infrastructure when dynamically assessing railway bridges under high-speed traffic,the damping properties considered in the calculation model significantly influen... To ensure the compatibility between rolling stock and infrastructure when dynamically assessing railway bridges under high-speed traffic,the damping properties considered in the calculation model significantly influence the predicted acceleration amplitude at resonance.However,due to the normative specifications of EN 1991-2,which are considered to be overly conservative,damping factors that are far below the actual damping have to be used when predicting vibrations of railway bridges,which means that accelerations at resonance tend to be overestimated to an uneconomical extent.Comparisons between damping factors prescribed by the standard and those identified based on in situ structure measurements always reveal a large discrepancy between reality and regulation.Given this background,this contribution presents a novel approach for defining the damping factor of railway bridges with ballasted tracks,where the damping factor for bridges is mathematically determined based on three different two-dimensional mechanical models.The basic principle of the approach for mathematically determining the damping factor is to separately define and superimpose the dissipative contributions of the supporting structure(including the substructure)and the superstructure.Using the results of a measurement campaign on 15 existing steel railway bridges in the Austrian rail network,the presented mechanical models are calibrated,and by analysing the energy dissipation in the ballasted track,guiding principles for practical application are defined.This guideline is intended to establish an alternative to the currently valid specifications of EN 1991-2,enabling the damping factor of railway bridges to be assessed in a realistic range by mathematical calculation and thus without the need for extensive in situ measurements on the individual structure.In this way,the existing potential of the infrastructure with regard to the damping properties of bridges can be utilised.This contribution focuses on steel bridges,but the mathematical approach for determining the damping factor applies equally to other bridge types(concrete,composite,or filler beam). 展开更多
关键词 Railway bridges Bridge dynamics dampING Track-bridge interaction Structural health monitoring Condition assessment
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Uniform Attractors for the Kirchhoff Type Suspension Bridge Equation with Nonlinear Damping and Memory Term
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作者 Ling XU Yanni WANG 《Journal of Mathematical Research with Applications》 2026年第1期71-86,共16页
The goal of this paper is to investigate the long-time dynamics of solutions to a Kirchhoff type suspension bridge equation with nonlinear damping and memory term.For this problem we establish the well-posedness and e... The goal of this paper is to investigate the long-time dynamics of solutions to a Kirchhoff type suspension bridge equation with nonlinear damping and memory term.For this problem we establish the well-posedness and existence of uniform attractor under some suitable assumptions on the nonlinear term g(u),the nonlinear damping f(u_(t))and the external force h(x,t).Specifically,the asymptotic compactness of the semigroup is verified by the energy reconstruction method. 展开更多
关键词 uniform attractor Kirchhoff type suspension bridge equation nonlinear damping memory term
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Data-Driven Prediction and Optimization of Mechanical Properties and Vibration Damping in Cast Iron-Granite-Epoxy Hybrid Composites
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作者 Girish Hariharan Vinyas +4 位作者 Gowrishankar Mandya Chennegowda Nitesh Kumar Shiva Kumar Deepak Doreswamy Subraya Krishna Bhat 《Computers, Materials & Continua》 2026年第3期537-573,共37页
This study presents a framework involving statistical modeling and machine learning to accurately predict and optimize the mechanical and damping properties of hybrid granite-epoxy(G-E)composites reinforced with cast ... This study presents a framework involving statistical modeling and machine learning to accurately predict and optimize the mechanical and damping properties of hybrid granite-epoxy(G-E)composites reinforced with cast iron(CI)filler particles.Hybrid G-E composite with added cast iron(CI)filler particles enhances stiffness,strength,and vibration damping,offering enhanced performance for vibration-sensitive engineering applications.Unlike conventional approaches,this work simultaneously employs Artificial Neural Networks(ANN)for highaccuracy property prediction and Response Surface Methodology(RSM)for in-depth analysis of factor interactions and optimization.A total of 24 experimental test data sets of varying input factors(granite weight%,epoxy weight%,and CI filler weight%)were utilized to train and test the prediction models using an ANN approach and further analyze the interaction effects using RSM.Mechanical properties,including tensile,compressive,and flexural strength,elastic modulus,density and damping properties measured under various testing conditions,were set as output parameters for prediction.This study analyzed and optimized the performance of the ANN model using Bayesian Regularization and Levenberg-Marquardt algorithms to identify the best performing number of neurons in the hidden layer for achieving the highest prediction accuracy.The proposed ANN framework achieved an exceptional average determination coefficient(R2)exceeding 99%,with Bayesian Regularization demonstrating remarkable stability in the 22-neuron range and minimal variation across all properties.RSM and ANN form a powerful framework for predicting and optimizing hybrid G-E composite properties,enabling efficient design for vibration-critical applications with reduced experimental effort and performance optimization. 展开更多
关键词 Hybrid granite epoxy composite artificial neural network response surface methodology mechanical strength damping ratio
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Structural vibration control using nonlinear damping amplifier friction vibration absorbers
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作者 S.CHOWDHURY S.ADHIKARI 《Applied Mathematics and Mechanics(English Edition)》 2025年第5期965-988,共24页
This paper introduces damping amplifier friction vibration absorbers(DAFVAs),compound damping amplifier friction vibration absorbers(CDAFVAs),nested damping amplifier friction vibration absorbers(NDAFVAs),and levered ... This paper introduces damping amplifier friction vibration absorbers(DAFVAs),compound damping amplifier friction vibration absorbers(CDAFVAs),nested damping amplifier friction vibration absorbers(NDAFVAs),and levered damping amplifier friction vibration absorbers(LDAFVAs)for controlling the structural vibrations and addressing the limitations of conventional tuned mass dampers(TMDs)and frictiontuned mass dampers(FTMDs).The closed-form analytical solution for the optimized design parameters is obtained using the H_(2)and H_(∞)optimization approaches.The efficiency of the recently established closed-form equations for the optimal design parameters is confirmed by the analytical examination.The closed form formulas for the dynamic responses of the main structure and the vibration absorbers are derived using the transfer matrix formulations.The foundation is provided by the harmonic and random-white noise excitations.Moreover,the effectiveness of the innovative dampers has been validated through numerical analysis.The optimal DAFVAs,CDAFVAs,NDAFVAs,and LDAFVAs exhibit at least 30%lower vibration reduction capacity compared with the optimal TMD.To demonstrate the effectiveness of the damping amplification mechanism,the novel absorbers are compared with a conventional FTMD.The results show that the optimized novel absorbers achieve at least 91%greater vibration reduction than the FTMD.These results show how the suggested designs might strengthen the structure's resilience to dynamic loads. 展开更多
关键词 damping amplifier friction vibration absorber(DAFVA) compound damping amplifier friction vibration absorber(CDAFVA) nested damping amplifier friction vibration absorber(NDAFVA) levered damping amplifier friction vibration absorber(LDAFVA) H2 and H∞optimization approaches
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Vibration reduction mechanism and characteristics evaluation of active elastic support/dry friction damper 被引量:1
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作者 Siji WANG Dafang LIN +2 位作者 Quankun LI Jiayao CHEN Yuan LIU 《Chinese Journal of Aeronautics》 2025年第4期333-348,共16页
This paper studies the coupling mechanism between the nonlinear stiffness and damping coefficients of Active Elastic Support/Dry Friction Damper(AESDFD)and rotor system.First,parameters for evaluating the vibration re... This paper studies the coupling mechanism between the nonlinear stiffness and damping coefficients of Active Elastic Support/Dry Friction Damper(AESDFD)and rotor system.First,parameters for evaluating the vibration reduction characteristics are proposed to facilitate the design of the AESDFD.To achieve this,the nonlinear friction force is initially represented as equivalent stiffness and damping coefficients,based on the ball-plate friction model.Second,three evaluation parameters—optimal slipping displacement,loss factor,and controllability—are proposed to reveal the vibration reduction characteristics of the AESDFD,alongside determining the optimal normal force.Subsequently,the finite element method,in conjunction with the ball-plate friction model,is introduced to formulate the governing equation of a low-pressure rotor system equipped with AESDFDs.The steady-state responses of the AESDFDs-rotor system are solved using the harmonic balance method combined with an efficient iteration method.Finally,the solutions are validated on the AESDFDs-rotor system both numerically and experimentally.The results indicate that controllability effectively assesses the vibration reduction performance of the AESDFD and is relatively insensitive to variations in low normal force.Away from the critical speed,the AESDFD suppresses vibration by altering the resonance position of the rotor system through its stiffness coefficient.Near the critical speed,vibration reduction is achieved primarily through energy dissipation by the damping coefficient.If the loss factor is less than one,the stiffness coefficient can diminish the vibration reduction effect of the damping coefficient.Notably,the optimal normal force of the AESDFD achieves optimal vibration reduction effect.This study reveals that changes in rotor system unbalance do not affect the vibration reduction characteristics of the AESDFD,with the same upper limit to the vibration reduction effect of the AESDFD. 展开更多
关键词 Active dry friction damper Low-pressure rotor system Vibration analysis Stiffness and damping coefficients Evaluation parameters Finite element method
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Treatment of One Case of Pediatric Hand-Foot-Mouth Disease with Spleen Dampness-Heat Syndrome Using Acupoint Application Therapy to Disperse Dampness,Expel Heat,and Unblock the Fu Organs
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作者 Wangsen Zhao Ziqing Wu 《Journal of Clinical and Nursing Research》 2025年第4期80-83,共4页
The high incidence of hand,foot,and mouth disease(HFMD)in children,coupled with improper management,can lead to complications,causing significant distress to both patients and their parents.This article reports on the... The high incidence of hand,foot,and mouth disease(HFMD)in children,coupled with improper management,can lead to complications,causing significant distress to both patients and their parents.This article reports on the successful treatment of a case of HFMD with dampness-heat accumulation in the spleen type using a therapeutic approach of applying herbal patches to acupoints to disperse dampness,promote heat dissipation,and unblock the fu organs.The herbs selected primarily include honeysuckle,Forsythia,and mint to relieve the exterior and promote heat dissipation;Agastache and magnolia bark to transform and dry dampness;Scutellaria,blackberry lily,and licorice to clear heat,detoxify,and benefit the throat;and magnolia bark and bitter orange to unblock the fu organs and purge heat.The flexible combination of these herbs with acupoints such as Shenque,Zhongwan,Tiantu,and Feishu fully leverages the synergistic effects of both the herbs and acupoints,resulting in a significant therapeutic effect.This approach provides valuable insights and methodologies for the prevention and treatment of HFMD in children. 展开更多
关键词 Pediatric hand-foot-mouth disease Spleen dampness-heat syndrome Acupoint application therapy Disperse dampness and expel heat to unblock the fu organs
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三仁汤通过抑制DAMPs/TLR4/NF-κB通路减轻HIV/AIDS湿热内蕴证患者炎症反应
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作者 姜庆成 张淼 +3 位作者 马素娜 王娟 潘万旗 许前磊 《辽宁中医杂志》 北大核心 2025年第10期116-121,共6页
目的 探究DAMPs/TLR4/NF-κB信号通路在HIV/AIDS湿热内蕴证炎症反应的作用机制和三仁汤的干预机制。方法 该研究选取某地区HIV/AIDS湿热内蕴证患者15例为实验组,健康人15例为对照组,HIV/AIDS湿热内蕴证患者接受中药三仁汤颗粒剂干预2个... 目的 探究DAMPs/TLR4/NF-κB信号通路在HIV/AIDS湿热内蕴证炎症反应的作用机制和三仁汤的干预机制。方法 该研究选取某地区HIV/AIDS湿热内蕴证患者15例为实验组,健康人15例为对照组,HIV/AIDS湿热内蕴证患者接受中药三仁汤颗粒剂干预2个月。利用流式细胞技术,检测分析CD^(+)_(3)T、CD^(+)_(4)T、CD^(+)_(8)T、CD^(+)_(4)/CD^(+)_(8)T等免疫学指标。运用Elisa、qPCR技术检测DAMPs/TLR4/NF-κB信号通路相关蛋白及炎症因子和mRNA的表达情况。结果 与健康对照组相比,HIV/AIDS湿热内蕴证组CD^(+)_(4)T淋巴细胞数显著降低,CD^(+)_(4)/CD^(+)_(8)T比值发生倒置,CRP、TNF-α、IL-6、HSP60、S100A8/A9、TLR4、NF-κB等蛋白及NF-κB p65、HMGB1、HSP70、IL-1β、IL-8等mRNA表达均显著上升,差异具统计学意义(P<0.05)。经三仁汤干预后,HIV/AIDS湿热内蕴证患者CD^(+)_(4)T淋巴细胞数回升,临床症状明显改善。同时,患者体内CRP、TNF-α、IL-1β、IL-6、HMGB1、HSP60、S100A8/A9、TLR4、NF-κB等蛋白及NF-κB p65、HMGB1、HSP60、HSP70、IL-1β、IL-8等mRNA表达均显著降低,差异同样具有统计学意义(P<0.05)。结论 DAMPs/TLR4/NF-κB信号通路在HIV/AIDS湿热内蕴证炎症反应中发挥重要作用,三仁汤可能通过抑制DAMPs/TLR4/NF-κB通路活化,减轻HIV/AIDS湿热内蕴证患者炎症反应。 展开更多
关键词 HIV/AIDS湿热内蕴证 炎症 dampS TLR4/NF-κB信号通路 三仁汤
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Equivalent damping of SDOF structure with Maxwell damper 被引量:5
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作者 Li Chuangdi Li Tun +1 位作者 Ban Dingwei Ge Xinguang 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2018年第3期627-639,共13页
To predict the maximum earthquake response of an SDOF structure with a Maxwell fluid damper or supplemental brace-viscous damper system using the seismic design response spectrum technique,a new approach is presented ... To predict the maximum earthquake response of an SDOF structure with a Maxwell fluid damper or supplemental brace-viscous damper system using the seismic design response spectrum technique,a new approach is presented to determine the first-and second-order equivalent viscous damping and stiffness,the peak responses,and the damper force of the above structure.Based on the fact that the dynamic characteristics of a general linear viscoelastically damped structure are fully determined by its free vibration properties and the relaxation time constants of a Maxwell fluid damper and supplemental brace-viscous damper system in engineering practice are all small,the method of improved multiple time scales and the equivalent criterion in which all free vibration properties are the same are used to obtain the first-and second-order equivalent viscous damping and stiffness of the above structure in closed form.The accuracy of the proposed method is higher and significantly better than that of the modal strain energy method.Furthermore,in the parametric range of the requirements of the Chinese "Code for Seismic Design of Buildings",the error of the proposed second-order equivalent system for the abovementioned engineering structure is not more than 0.5%. 展开更多
关键词 Maxwell damper supplemental brace-viscous damper system equivalent viscous damping response spectrum method maximum response of damper force
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基于DAMP信号通路的铁死亡在急性肾损伤向慢性肾病转化中的机制及其调控策略
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作者 刘泽 李俊杰 +4 位作者 苏诗宇 唐倩茹 李卿 李阿芳 李勇 《湘南学院学报(医学版)》 2025年第4期75-78,共4页
急性肾损伤(AKI)向慢性肾病(CKD)的转化是肾脏疾病进展的关键环节,其机制尚未完全阐明。研究表明,铁死亡作为一种铁依赖的脂质过氧化细胞死亡方式,在肾小管上皮细胞损伤及AKI-CKD转化中发挥核心作用。损伤相关分子模式(DAMPs)信号通路... 急性肾损伤(AKI)向慢性肾病(CKD)的转化是肾脏疾病进展的关键环节,其机制尚未完全阐明。研究表明,铁死亡作为一种铁依赖的脂质过氧化细胞死亡方式,在肾小管上皮细胞损伤及AKI-CKD转化中发挥核心作用。损伤相关分子模式(DAMPs)信号通路通过识别内源性危险信号(如HMGB1、mtDNA),激活炎症级联反应并放大铁死亡效应,形成“铁死亡-DAMP通路激活”的循环,促使AKI向CKD转化。本文综述铁死亡的特征及其在AKI-CKD转化中的作用,解析DAMP信号通路与铁死亡的交叉调控机制,探讨植源性活性成分通过激活PGC-1α调控线粒体稳态、抑制DAMP释放及铁死亡的可行性,为AKI-CKD转化的机制研究和临床干预提供参考。 展开更多
关键词 急性肾损伤 慢性肾病 铁死亡 damp信号通路 PGC-1Α
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Trial-Manufacture and Experimental Study of Particle Damping Boring Bar for Deep Hole Boring of 7075 Aluminum Alloy 被引量:2
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作者 HUANG Yi HAN Jianxin DONG Qingyun 《Transactions of Nanjing University of Aeronautics and Astronautics》 2025年第1期123-136,共14页
7075 aluminum alloy is often used as an important load-bearing structure in aircraft industry due to its superior mechanical properties.During the process of deep hole boring,the boring bar is prone to vibrate because... 7075 aluminum alloy is often used as an important load-bearing structure in aircraft industry due to its superior mechanical properties.During the process of deep hole boring,the boring bar is prone to vibrate because of its limited machining space,bad environment and large elongation induced low stiffness.To reduce vibration and improve machined surface quality,a particle damping boring bar,filled with particles in its inside damping block,is designed based on the theory of vibration control.The theoretical damping coefficient is determined,then the boring bar structure is designed and trial-manufactured.Experimental studies through impact testing show that cemented carbide particles with a diameter of 5 mm and a filling rate of 70% achieve a damping ratio of 19.386%,providing excellent vibration reduction capabilities,which may reduce the possibility of boring vibration.Then,experiments are setup to investigate its vibration reduction performance during deep hole boring of 7075 aluminum alloy.To observe more obviously,severe working conditions are adopted and carried out to acquire the time domain vibration signal of the head of the boring bar and the surface morphologies and roughness values of the workpieces.By comparing different experimental results,it is found that the designed boring bar could reduce the maximum vibration amplitude by up to 81.01% and the surface roughness value by up to 47.09% compared with the ordinary boring bar in two sets of experiments,proving that the designed boring bar can effectively reduce vibration.This study can offer certain valuable insights for the machining of this material. 展开更多
关键词 7075 aluminum alloy boring bar vibration reduction particle damping
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A Review of the Hydrodynamic Damping Characteristics of Blade-like Structures:Focus on the Quantitative Identification Methods and Key Influencing Parameters 被引量:1
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作者 Yongshun Zeng Zhaohui Qian +1 位作者 Jiayun Zhang Zhifeng Yao 《哈尔滨工程大学学报(英文版)》 2025年第1期21-34,共14页
Ocean energy has progressively gained considerable interest due to its sufficient potential to meet the world’s energy demand,and the blade is the core component in electricity generation from the ocean current.Howev... Ocean energy has progressively gained considerable interest due to its sufficient potential to meet the world’s energy demand,and the blade is the core component in electricity generation from the ocean current.However,the widened hydraulic excitation frequency may satisfy the blade resonance due to the time variation in the velocity and angle of attack of the ocean current,even resulting in blade fatigue and destructively interfering with grid stability.A key parameter that determines the resonance amplitude of the blade is the hydrodynamic damping ratio(HDR).However,HDR is difficult to obtain due to the complex fluid-structure interaction(FSI).Therefore,a literature review was conducted on the hydrodynamic damping characteristics of blade-like structures.The experimental and simulation methods used to identify and obtain the HDR quantitatively were described,placing emphasis on the experimental processes and simulation setups.Moreover,the accuracy and efficiency of different simulation methods were compared,and the modal work approach was recommended.The effects of key typical parameters,including flow velocity,angle of attack,gap,rotational speed,and cavitation,on the HDR were then summarized,and the suggestions on operating conditions were presented from the perspective of increasing the HDR.Subsequently,considering multiple flow parameters,several theoretical derivations and semi-empirical prediction formulas for HDR were introduced,and the accuracy and application were discussed.Based on the shortcomings of the existing research,the direction of future research was finally determined.The current work offers a clear understanding of the HDR of blade-like structures,which could improve the evaluation accuracy of flow-induced vibration in the design stage. 展开更多
关键词 Blade fatigue Hydrodynamic damping ratio Identification method Affecting factors Prediction formula
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Research on Vibration Control of Pump Valve Pipeline System Based on Active Damping Device 被引量:1
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作者 Hao-zhe Zhu Li-dong He Qing-wang Qin 《风机技术》 2025年第2期78-83,共6页
Pump valve pipeline vibration brings serious safety hazards to the operation of the equipment,for the pump valve system in the process of variable flow,variable speed,variable openings lead to excessive pipeline vibra... Pump valve pipeline vibration brings serious safety hazards to the operation of the equipment,for the pump valve system in the process of variable flow,variable speed,variable openings lead to excessive pipeline vibration.An active damping device(ADD)is used to the vibration of the pump valve pipeline system to apply the control force,to achieve the active control of the pipeline vibration.A pump-valve pipeline vibration test bench was built to compare the control effect of active damping device on pipeline vibration under different pump valve working conditions,and the results show that applying ADD control could effectively suppress the vibration of the pump valve pipeline and enhance the stability of the equipment during operation.At different pump operating rotation frequencies,the vibration amplitude of the pump valve pipeline in working frequency and its multiple frequencies are also effectively suppressed,with the maximum amplitude reduction of more than 60%.For the valve vibration caused by different operating openings,the vibration of the highest reduction of 68%,and the centrifugal pump drive shaft vi-bration reduced by up to 73%,which provides a new idea for vibration control of pump valve pipeline system. 展开更多
关键词 Active damping Device Active Control ACTUATOR Pump Valve Pipeline
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Clinical evaluation of strengthening spleen and draining dampness in the treatment of idiopathic membranous nephropathy: a retrospective 10-year follow-up study 被引量:1
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作者 KE Tianxingjian CHEN Wanjia +6 位作者 XIANG Ling DENG Yueyi WANG Yiquan LIU Wangyi XING Yue LU Zhenzhen GAO Hongzhi 《Journal of Traditional Chinese Medicine》 2025年第4期881-890,共10页
OBJECTIVE:To evaluate the 10-year therapeutic efficacy of Traditional Chinese Medicine(TCM)using the Strengthening Spleen and Draining Dampness therapy in the management of idiopathic membranous nephropathy(IMN).METHO... OBJECTIVE:To evaluate the 10-year therapeutic efficacy of Traditional Chinese Medicine(TCM)using the Strengthening Spleen and Draining Dampness therapy in the management of idiopathic membranous nephropathy(IMN).METHODS:A single-center,retrospective analysis was conducted on patients diagnosed with IMN who met predefined inclusion and exclusion criteria.Data were collected from the Department of Nephrology at Longhua Hospital,affiliated with Shanghai University of Traditional Chinese Medicine,between January 2007 and December 2011.Clinical parameters including 24-h urinary protein,serum albumin,serum creatinine,and estimated glomerular filtration rate(e GFR,EPI)were assessed at baseline and at 1,3,5,and 10 years of follow-up.The efficacy of the Strengthening Spleen and Draining Dampness therapy was analyzed using repeated measures analysis of variance(ANOVA).Kaplan-Meier survival curves and multivariate proportional hazards model(Cox regression models)were employed to identify factors associated with treatment outcomes.RESULTS:A total of 265 patients were included,with a median follow-up duration of 96 months(36,122).TCM treatment significantly reduced 24-h urinary protein levels(P<0.001),and increased serum albumin levels(P<0.001),while serum creatinine remained stable(P=0.187).Remission rates at 1,3,5,and 10 years were 52.81%,69.71%,68.39%,and 72.36%,respectively,and the rates of avoiding composite outcome events at the same intervals were 98.27%,94.29%,94.19%,and 93.50%.In the subgroup receiving TCM only,remission rates were 56.67%,84.44%,76.32%,and 82.86%.For patients treated initially with Western Medicine followed by TCM,the rates were 52.83%,65.85%,67.47%and 67.75%.In the cohort of patients who received TCM as their first-line therapy,remission rates were 49.23%,62.50%,61.76%,and 69.23%.Multivariate Cox regression analysis revealed that the duration of TCM treatment[hazard ratio(HR)=0.826,95%confidence interval(CI)(0.779,0.876),P<0.001],presence of hypertension[HR=1.912,95%CI(1.181,3.094),P=0.008],baseline serum albumin level[HR=0.930,95%CI(0.894,0.969),P<0.001],and the rate of serum albumin increase within the first year of treatment[HR=0.930,95%CI(0.909,0.957),P<0.001]were significantly associated with clinical outcomes.CONCLUSION:The Strengthening Spleen and Draining Dampness therapy demonstrated robust short-and longterm efficacy in treating IMN,with high rates of remission and renal survival over 10 years.Key factors influencing clinical remission included the duration of TCM treatment,baseline serum albumin levels,the presence of hypertension,and the rate of increase in serum albumin within the first year.These findings suggest that this TCM approach provides a viable long-term treatment option for IMN. 展开更多
关键词 glomerulonephritis membranous long-term renal survival risk factors efficacy evaluation strengthening spleen and draining dampness
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Study on the diagnostic criteria of syndrome of dampness obstruction in idiopathic membranous nephropathy based on expert consensus 被引量:1
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作者 WANG Dan HUANG Xiaoyan +5 位作者 LI Ping HONG Xiaofan ZHANG Yumin WANG Rongrong BAO Kun LIANG Xing 《Journal of Traditional Chinese Medicine》 2025年第1期167-175,共9页
OBJECTIVE:To reach consensus on the diagnostic criteria of syndrome of dampness obstruction in idiopathic membranous nephropathy(IMN)patients by literature research and expert investigation(interviews and a Delphi met... OBJECTIVE:To reach consensus on the diagnostic criteria of syndrome of dampness obstruction in idiopathic membranous nephropathy(IMN)patients by literature research and expert investigation(interviews and a Delphi method).METHODS:Our study was consistent with T/CACM 1336-2020.We searched the monographs and references published in the past 40 years(1983-2022),and established the diagnostic criteria pool of waterdampness syndrome and dampness-turbidity syndrome in Traditional Chinese Medicine(TCM)based on literature by using frequency statistics and correlation analysis.Expert investigation(interview method and two rounds of Delphi method)was used to form the diagnostic criteria of water-dampness syndrome and dampnessturbidity syndrome of idiopathic membranous nephropathy.Clinical diagnostic test research was carried out,and compared with“Diagnostic Criteria for dampness syndrome”(T/CACM 1454-2023)to evaluate the authenticity,reliability and clinical application value of the standard.RESULTS:A total of 122 relevant guides,standards,monographs and documents were included through searching books and Chinese databases.Four experts were interviewed and two rounds of delphi method(75 experts nationwide)were carried out.The experts'opinions are relatively concentrated and the differences are small.Based on the weight of each index,the diagnostic criteria indexes of water-dampness syndrome and dampness-turbidity syndrome were selected.After discussion by the core group members,the diagnostic model of"necessary symptoms and optional symptoms"was established,and the final diagnostic criteria of waterdampness syndrome and dampness-turbidity syndrome were established.One hundred and ninety-one inpatients and outpatients of Guangdong Provincial Hospital of Chinese Medicine from January 2021 to February 2023 were included in Diagnostic test study.There was no statistical difference in gender,age and course of disease(P>0.05).The sensitivity and specificity of the trial standard were 90.34%and 73.33%respectively,while the sensitivity and specificity of T/CACM 1454-2023 were 99.43%and 6.67%,respectively.CONCLUSIONS:The consensus-based diagnostic criteria for IMN can be widely incorporated in TCM.A further clinical study will be conducted to analyze the diagnosis value and cut-off score of our IMN criteria. 展开更多
关键词 glomerulonephritis membranous diagnostic tests routine syndrome of dampness obstruction combination of disease and syndrome syndrome diagnostic criteria
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Time-delay damping theory
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作者 洪峰 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2002年第2期303-309,共7页
In this paper,existing damping theories are briefly reviewed.On the basis of the existing damping theories,a new kind of damping theory,i.e.,the time-delay damping theory,is developed.In the time-delay damping theory,... In this paper,existing damping theories are briefly reviewed.On the basis of the existing damping theories,a new kind of damping theory,i.e.,the time-delay damping theory,is developed.In the time-delay damping theory,the damping force is considered to be directly proportional to the increment of displacement.The response analysis of an SDOF time-delay damping system is carried out,and the methods for obtaining the solution for a time-delay damping system in the time domain as well as the frequency domain are given.The comparison between results from different damping theories shows that the time-delay damping theory is both reasonable and convenient. 展开更多
关键词 viscous damping complex damping time-delay damping damping force
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Dampness syndrome aggravates T helper 17/regulatory T imbalance to promote renal injury in rats with experimental membranous nephropathy
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作者 SHAN Wenjun GU Haowen +6 位作者 GUAN Haiyu LI Ping WANG Yi HAN Miaoru WANG Houchun HUANG Xiaoyan BAO Kun 《Journal of Traditional Chinese Medicine》 2025年第5期1028-1039,共12页
OBJECTIVE:To examine the T helper 17(Th17)/regulatory T(Treg)immune balance in passive Heymann nephritis(PHN)rats with dampness syndrome(DS).METHODS:Rats were divided into four groups:normal control(NC),PHN model,PHN+... OBJECTIVE:To examine the T helper 17(Th17)/regulatory T(Treg)immune balance in passive Heymann nephritis(PHN)rats with dampness syndrome(DS).METHODS:Rats were divided into four groups:normal control(NC),PHN model,PHN+DS model,and DS model.The DS model was created by administering lard,a 60%cold sucrose solution,and Chinese Baijiu viagavage.In contrast,PHN was induced in male Sprague-Dawley rats by injecting anti-Fx1A serum into the tail vein.The general condition of the rats was assessed,while the levels of urine protein,albumin,and serum creatinine were measured using commercially available kits.Pathological renal damage was evaluated using hematoxylin and eosin,periodic acid-schiff,and periodic acid-silver methenamine staining,while podocyte damage was assessed through immunohistochemistry.The proportions of Th17 cells and Treg cells in peripheral blood mononuclear cells were quantified by flow cytometry.Plasma cytokine levels of interleukin 17,transforming growth factor-β1,and interleukin 6 were determined by enzyme-linked immunosorbent assay.RESULTS:This study demonstrated a significant increase in proteinuria and total cholesterol levels in PHN rats with DS,along with more severe histopathological kidney damage.DS exacerbated podocyte damage in PHN rats.Additionally,the number of Treg cells was significantly reduced,while the ratio of Th17/Treg cells was significantly elevated in PHN rats with DS.CONCLUSION:In conclusion,the findings of our study indicate that the presence of DS exacerbates renal injury in PHN,a rat model used to simulate experimental membranous nephropathy.This observation may be closely linked to the exacerbation of the Th17/Treg imbalance and podocyte injury in PHN rats induced by DS. 展开更多
关键词 GLOMERULONEPHRITIS MEMBRANOUS Th17 cells T-LYMPHOCYTES REGULATORY dampness syndrome
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Influence of an Adding Damping Device in a Moonpool on the Heave Motion of a Drilling Ship Part I:Experiment
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作者 WEI Qi GU Jia-yang +3 位作者 LIU Wei-min LYU Hong-guan TAO Yan-wu HU Fang-xin 《China Ocean Engineering》 2025年第2期191-208,共18页
On the basis of the model tests,this paper explores the coupled hydrodynamic performance of the moonpool and the hull.This study aims to compare and analyze the variation in the hull heave response between the piston ... On the basis of the model tests,this paper explores the coupled hydrodynamic performance of the moonpool and the hull.This study aims to compare and analyze the variation in the hull heave response between the piston resonance state of the moonpool under wave excitation and the non-resonance state of the moonpool under wave-current excitation.A novel damping device specifically designed and fabricated for stepped moonpools has been developed.Before and after the installation of the damping device,the free surface response characteristics of the moonpool and heave motion response characteristics of the hull are compared.The findings show a clear correlation between the current speed and heave response characteristics of the hull.During the seakeeping design phase of the drilling vessel,the current speed is an additional critical factor that cannot be disregarded,alongside the moonpool effect.A correlation exists between the fluid dynamics occurring within the moonpool and the heave motion of the vessel hull.A reduction in the amplitude of the motion of the moonpool water results in a decrease in the heave motion of the hull.This study provides a reference for alleviating the seakeeping of a drill ship’s heave response and enhancing the safety and efficiency of the operation. 展开更多
关键词 heave motion damping device moonpool model test wave-current excitation
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Tropical Cyclone Simulations:The Impact of Model Top/Damping Layer and the Role of Stratospheric Gravity Waves
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作者 Xu WANG Yuan WANG +2 位作者 Lifeng ZHANG Yun ZHANG Jiping GUAN 《Advances in Atmospheric Sciences》 2025年第11期2290-2304,共15页
This paper investigates the impact of the model top and damping layer on the numerical simulation of tropical cyclones(TCs)and reveals the significant role of stratospheric gravity waves(SGWs).TCs can generate SGWs,wh... This paper investigates the impact of the model top and damping layer on the numerical simulation of tropical cyclones(TCs)and reveals the significant role of stratospheric gravity waves(SGWs).TCs can generate SGWs,which propagate upward and outward into the stratosphere.These SGWs can reach the damping layer,which is a consequence of the numerical scheme employed,where they can affect the tangential circulation through the dragging and forcing processes.In models with a higher top boundary,this tangential circulation develops far from the TC and has minimal direct impact on TC intensity.By comparison,in models with a lower top(e.g.,20 km),the damping layer is located just above the top of the TC.The SGW dragging in the damping layer and the consequent tangential force can thus induce ascent outside the eyewall,promote latent heat release,tilt the eyewall,and enlarge the inner-core radius.This process will reduce inner-core vorticity advection within the boundary layer,and eventually inhibits the intensification of the TC.This suggests that when the thickness of the damping layer is 5 km,the TC numerical model top height should be at least higher than 20 km to generate more accurate simulations. 展开更多
关键词 gravity waves STRATOSPHERE tropical cyclones numerical simulations damping layer model top
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The Global Attractor of 2D g-Navier- Stokes Equations with Damping and Delay
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作者 WANG Xiaoxia JIANG Jinping ZHANG Fukun 《Wuhan University Journal of Natural Sciences》 2025年第3期269-275,共7页
In this article,the global attractors of 2D g-Navier-Stokes equations are obtained in the space of C_(Hg) and CVg respectively.When the external force f is sufficiently small,the studies indicate that the global attra... In this article,the global attractors of 2D g-Navier-Stokes equations are obtained in the space of C_(Hg) and CVg respectively.When the external force f is sufficiently small,the studies indicate that the global attractor in C_(Hg) is equal to the global attractor in C_(Vg). 展开更多
关键词 global attractor g-Navier-Stokes equation dampING DELAY
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Analytical Solutions for 1-Dimensional Peridynamic Systems by Considering the Effect of Damping
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作者 Zhenghao Yang Erkan Oterkus +1 位作者 Selda Oterkus Konstantin Naumenko 《Computer Modeling in Engineering & Sciences》 2025年第5期2491-2508,共18页
For the solution of peridynamic equations of motion,a meshless approach is typically used instead of utilizing semi-analytical or mesh-based approaches.In contrast,the literature has limited analytical solutions.This ... For the solution of peridynamic equations of motion,a meshless approach is typically used instead of utilizing semi-analytical or mesh-based approaches.In contrast,the literature has limited analytical solutions.This study develops a novel analytical solution for one-dimensional peridynamic models,considering the effect of damping.After demonstrating the details of the analytical solution,various demonstration problems are presented.First,the free vibration of a damped system is considered for under-damped and critically damped conditions.Peridynamic solutions and results from the classical theory are compared against each other,and excellent agreement is observed between the two approaches.Next,forced vibration analyses of undamped and damped conditions are performed.In addition,the effect of horizon size is investigated.It is shown that for smaller horizon sizes,peridynamic results agree well with classical results,whereas results from these two approaches deviate from each other as the horizon size increases. 展开更多
关键词 PERIDYNAMICS ANALYTICAL dampING
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