A histological and ultrastructural observation of CHA implanted intra-muscularly and subcutaneously had been reported- Our results showed that a mildinflammation developed at the early stage and disappeared 2 weeks af...A histological and ultrastructural observation of CHA implanted intra-muscularly and subcutaneously had been reported- Our results showed that a mildinflammation developed at the early stage and disappeared 2 weeks after implanta-tion. The infiltrating cells were mainly monocyte-macrophages, a number of fi-broblasts followed macrophags closely. It was possible that as CHA degrades,monocyte - mac rop hages continuouslyre leased inflammatory factors, thus enhanc-ing fibroblast proliferation activity and tissue regeneration. In addition, the het-erotopic calcification of collagen matrix was observed, suggesting that CHA prthmoted calcification deposition.展开更多
文摘A histological and ultrastructural observation of CHA implanted intra-muscularly and subcutaneously had been reported- Our results showed that a mildinflammation developed at the early stage and disappeared 2 weeks after implanta-tion. The infiltrating cells were mainly monocyte-macrophages, a number of fi-broblasts followed macrophags closely. It was possible that as CHA degrades,monocyte - mac rop hages continuouslyre leased inflammatory factors, thus enhanc-ing fibroblast proliferation activity and tissue regeneration. In addition, the het-erotopic calcification of collagen matrix was observed, suggesting that CHA prthmoted calcification deposition.
