Herein,we present the synthesis of peptide-decorated organotin sulfide clusters via strain-promoted azide–alkyne cycloaddition.Overall,the target compounds are accessed in three major steps.The first step represents ...Herein,we present the synthesis of peptide-decorated organotin sulfide clusters via strain-promoted azide–alkyne cycloaddition.Overall,the target compounds are accessed in three major steps.The first step represents the synthesis of azide-terminated organotin sulfide clusters of the general type[(RSn)3S4Cl].In the second step,these are reacted with a complementary cyclooctyne that exhibits terminal amine functionality.According to electrospray-ionization mass spectrometry,the terminal amino group at the alkyne undergoes an intramolecular condensation reaction.展开更多
文摘Herein,we present the synthesis of peptide-decorated organotin sulfide clusters via strain-promoted azide–alkyne cycloaddition.Overall,the target compounds are accessed in three major steps.The first step represents the synthesis of azide-terminated organotin sulfide clusters of the general type[(RSn)3S4Cl].In the second step,these are reacted with a complementary cyclooctyne that exhibits terminal amine functionality.According to electrospray-ionization mass spectrometry,the terminal amino group at the alkyne undergoes an intramolecular condensation reaction.
