Purpose:To verify whether there exists any difference in higher order aberrations after undergoing myopic LASIK(laser in situ keratomileusis)with conventional ablation and customized ablation in different eyes of the ...Purpose:To verify whether there exists any difference in higher order aberrations after undergoing myopic LASIK(laser in situ keratomileusis)with conventional ablation and customized ablation in different eyes of the same patient.Methods:This was a prospective randomized study of 54 myopic eyes(27 patients)that underwent LASIK using the Nidek EC-5000 ex-cimer laser system(Nidek,Gamagori,Japan).Topography-guided customized aspheric treatment zone(CATz)was used in the first eye of the patient(study group)and the other eye of the same patient was operated on with conventional ablation(control group).Higher order aberrations[root-mean-square(RMS)in the 5-mm zone]of both groups were observed with the Nidek OPD-Scan aberrometer before and 3 months after LASIK.Preoperative mean refractive error was similar between two eyes of the same patient(t=?0.577,P>0.05).Results:Preoperatively,higher order aberrations(RMS in the 5-mm zone)in the CATz ablation and conventional groups were(0.3600±0.0341)μm and(0.2680±0.1421)μm,respectively.This difference was not statistically significant(t=1.292,P>0.05).Three months after LASIK,higher order aberrations(RMS in 5-mm zone)in the CATz ablation and conventional groups were(0.3627±0.1510)μm and(0.3991±0.1582)μm,respectively.No statistically significant difference was noted between pre-and postoperative higher order aberrations in the CATz group(t=?0.047,P>0.05).However,a statistically significant increase in higher order aberrations was observed after conventional ablation(t=?5.261,P<0.05).A statistically sig-nificant difference was noted in the increase of higher order aberrations after LASIK between groups(t=?2.050,P=0.045).Con-clusion:LASIK with conventional ablation and topography-guided CATz ablation resulted in the same BSCVA(best specta-cle-corrected visual acuity)3 month after LASIK.Higher order aberrations were increased,but the increase of higher order ab-errations after customized ablation treatment was less than that after conventional ablation.展开更多
Background:Several planning algorithms have been developed for topography-guided custom ablation treatment(T-CAT),but each has its own deficiencies.The purpose of this study is to demonstrate the potential of a novel ...Background:Several planning algorithms have been developed for topography-guided custom ablation treatment(T-CAT),but each has its own deficiencies.The purpose of this study is to demonstrate the potential of a novel mutual comparative analysis(MCA)informed by manifest refraction and corneal topographic data and the patient’s subjective perception in correcting ametropia.Methods:This retrospective review included patients with significant preoperative differences in the power or axis of astigmatism according to the manifest refraction and corneal topographic data(power>0.75 D and/or axis>10°).T-CAT planning was designed using MCA.Follow-ups were conducted for at least 6 months.Results:Seventy-nine patients(121 eyes)were included.The mean preoperative deviation in the astigmatic power and axis were 0.72±0.43 D and 20.18±23.68°,respectively.The average oculus residual astigmatism(ORA)was 0.81±0.32 D(range:0.08–1.66 D).Six months postoperatively,the mean spherical equivalent refraction was 0.04±0.42 D,and the mean cylinder was−0.27±0.24 D.The mean efficacy and safety indices were 1.10 and 1.15,respectively.The uncorrected distance visual acuity in 92%of the eyes was the same or better than the corrected distance visual acuity.The angle of error was±5°in 61%of eyes and±15°in 84%of eyes.Residual astigmatism was≤0.5 D in 91%of eyes.Optical quality and photopic contrast sensitivity did not change significantly(p>0.05),and the scotopic contrast sensitivity decreased at 3,6,and 12 cpd(p<0.05).The vertical coma and horizontal coma of the anterior corneal surface significantly decreased postoperatively but increased during follow-up.Conclusions:The MCA demonstrated safety,efficacy,accuracy,predictability,and stability and can be used as a complementary and feasible method for T-CAT.展开更多
Background:Several planning algorithms have been developed for topography-guided custom ablation treatment(T-CAT),but each has its own deficiencies.The purpose of this study is to demonstrate the potential of a novel ...Background:Several planning algorithms have been developed for topography-guided custom ablation treatment(T-CAT),but each has its own deficiencies.The purpose of this study is to demonstrate the potential of a novel mutual comparative analysis(MCA)informed by manifest refraction and corneal topographic data and the patient's subjective perception in correcting ametropia.Methods:This retrospective review included patients with significant preoperative diferences in the power or axis of astigmatism according to the manifest refraction and corneal topographic data(power>0.75 D and/or axis>10°).T-CAT planning was designed using MCA.Follow-ups were conducted for at least 6 months.Results:Seventy-nine patients(121 eyes)were included.The mean preoperative deviation in the astigmatic power and axis were 0.72±0.43 D and 20.18±23.68°,respectively.The average oculus residual astigmatism(ORA)was 0.81±0.32 D(range:0.08-1.66 D).Six months postoperatively,the mean spherical equivalent refraction was 0.04±0.42 D,and the mean cylinder was-0.27±0.24 D.The mean efficacy and safety indices were 1.10 and 1.15,respectively.The uncorrected distance visual acuity in 92%of the eyes was the same or better than the corrected distance visual acuity.The angle of error was±5°in 61%of eyes and±15°in 84%of eyes.Residual astigmatism was≤0.5 D in 91%of eyes.Optical quality and photopic contrast sensitivity did not change significantly(P>0.05),and the scotopic contrast sensitivity decreased at 3,6,and 12 cpd(P<0.05).The vertical coma and horizontal coma of the anterior corneal surface significantly decreased postoperatively but increased during follow-up.Conclusions:The MCA was demonstrated safety,ficacy,accuracy,predictability,and stability and can be used as a complementary and feasible method for T-CAT.展开更多
文摘Purpose:To verify whether there exists any difference in higher order aberrations after undergoing myopic LASIK(laser in situ keratomileusis)with conventional ablation and customized ablation in different eyes of the same patient.Methods:This was a prospective randomized study of 54 myopic eyes(27 patients)that underwent LASIK using the Nidek EC-5000 ex-cimer laser system(Nidek,Gamagori,Japan).Topography-guided customized aspheric treatment zone(CATz)was used in the first eye of the patient(study group)and the other eye of the same patient was operated on with conventional ablation(control group).Higher order aberrations[root-mean-square(RMS)in the 5-mm zone]of both groups were observed with the Nidek OPD-Scan aberrometer before and 3 months after LASIK.Preoperative mean refractive error was similar between two eyes of the same patient(t=?0.577,P>0.05).Results:Preoperatively,higher order aberrations(RMS in the 5-mm zone)in the CATz ablation and conventional groups were(0.3600±0.0341)μm and(0.2680±0.1421)μm,respectively.This difference was not statistically significant(t=1.292,P>0.05).Three months after LASIK,higher order aberrations(RMS in 5-mm zone)in the CATz ablation and conventional groups were(0.3627±0.1510)μm and(0.3991±0.1582)μm,respectively.No statistically significant difference was noted between pre-and postoperative higher order aberrations in the CATz group(t=?0.047,P>0.05).However,a statistically significant increase in higher order aberrations was observed after conventional ablation(t=?5.261,P<0.05).A statistically sig-nificant difference was noted in the increase of higher order aberrations after LASIK between groups(t=?2.050,P=0.045).Con-clusion:LASIK with conventional ablation and topography-guided CATz ablation resulted in the same BSCVA(best specta-cle-corrected visual acuity)3 month after LASIK.Higher order aberrations were increased,but the increase of higher order ab-errations after customized ablation treatment was less than that after conventional ablation.
文摘Background:Several planning algorithms have been developed for topography-guided custom ablation treatment(T-CAT),but each has its own deficiencies.The purpose of this study is to demonstrate the potential of a novel mutual comparative analysis(MCA)informed by manifest refraction and corneal topographic data and the patient’s subjective perception in correcting ametropia.Methods:This retrospective review included patients with significant preoperative differences in the power or axis of astigmatism according to the manifest refraction and corneal topographic data(power>0.75 D and/or axis>10°).T-CAT planning was designed using MCA.Follow-ups were conducted for at least 6 months.Results:Seventy-nine patients(121 eyes)were included.The mean preoperative deviation in the astigmatic power and axis were 0.72±0.43 D and 20.18±23.68°,respectively.The average oculus residual astigmatism(ORA)was 0.81±0.32 D(range:0.08–1.66 D).Six months postoperatively,the mean spherical equivalent refraction was 0.04±0.42 D,and the mean cylinder was−0.27±0.24 D.The mean efficacy and safety indices were 1.10 and 1.15,respectively.The uncorrected distance visual acuity in 92%of the eyes was the same or better than the corrected distance visual acuity.The angle of error was±5°in 61%of eyes and±15°in 84%of eyes.Residual astigmatism was≤0.5 D in 91%of eyes.Optical quality and photopic contrast sensitivity did not change significantly(p>0.05),and the scotopic contrast sensitivity decreased at 3,6,and 12 cpd(p<0.05).The vertical coma and horizontal coma of the anterior corneal surface significantly decreased postoperatively but increased during follow-up.Conclusions:The MCA demonstrated safety,efficacy,accuracy,predictability,and stability and can be used as a complementary and feasible method for T-CAT.
文摘Background:Several planning algorithms have been developed for topography-guided custom ablation treatment(T-CAT),but each has its own deficiencies.The purpose of this study is to demonstrate the potential of a novel mutual comparative analysis(MCA)informed by manifest refraction and corneal topographic data and the patient's subjective perception in correcting ametropia.Methods:This retrospective review included patients with significant preoperative diferences in the power or axis of astigmatism according to the manifest refraction and corneal topographic data(power>0.75 D and/or axis>10°).T-CAT planning was designed using MCA.Follow-ups were conducted for at least 6 months.Results:Seventy-nine patients(121 eyes)were included.The mean preoperative deviation in the astigmatic power and axis were 0.72±0.43 D and 20.18±23.68°,respectively.The average oculus residual astigmatism(ORA)was 0.81±0.32 D(range:0.08-1.66 D).Six months postoperatively,the mean spherical equivalent refraction was 0.04±0.42 D,and the mean cylinder was-0.27±0.24 D.The mean efficacy and safety indices were 1.10 and 1.15,respectively.The uncorrected distance visual acuity in 92%of the eyes was the same or better than the corrected distance visual acuity.The angle of error was±5°in 61%of eyes and±15°in 84%of eyes.Residual astigmatism was≤0.5 D in 91%of eyes.Optical quality and photopic contrast sensitivity did not change significantly(P>0.05),and the scotopic contrast sensitivity decreased at 3,6,and 12 cpd(P<0.05).The vertical coma and horizontal coma of the anterior corneal surface significantly decreased postoperatively but increased during follow-up.Conclusions:The MCA was demonstrated safety,ficacy,accuracy,predictability,and stability and can be used as a complementary and feasible method for T-CAT.
