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Biquaternionic Model of Electro-Gravimagnetic Field, Charges and Currents. Law of Inertia
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作者 L. A. Alexeyeva 《Journal of Modern Physics》 2016年第5期435-444,共10页
One the base of Maxwell and Dirac equations the one biquaternionic model of electro-gravimagnetic (EGM) fields is considered. The closed system of biquaternionic wave equations is constructed for determination of free... One the base of Maxwell and Dirac equations the one biquaternionic model of electro-gravimagnetic (EGM) fields is considered. The closed system of biquaternionic wave equations is constructed for determination of free system of electric and gravimagnetic charges and currents and generated by them EGM-field. By using generalized functions theory the fundamental and regular solutions of this system are determined and some of them are considered (spinors, plane waves, shock EGM-waves and others). The properties of these solutions are investigated. 展开更多
关键词 Biquaternion Bigradient Biwave Equation Electro-Gravimagnetic Field Electric Charge Gravimagnetic Charge Current Maxwell Equations First Newton Law
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Currents from relativistic laser-plasma interaction as a novel metrology for the system stability of high-repetition-rate laser secondary sources 被引量:1
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作者 Michael Ehret Iuliana-Mariana Vladisavlevici +16 位作者 Philip Wykeham Bradford Jakub Cikhardt Evgeny Filippov Jose Luis Henares Rubén Hernández Martín Diego de Luis JoséAntonio Pérez-Hernández Pablo Vicente Tomas Burian Enrique García-García Juan Hernández Cruz Mendez Marta Olivar Ruíz Óscar Varela Maria Dolores Rodríguez Frías João Jorge Santos Giancarlo Gatti 《Matter and Radiation at Extremes》 2025年第2期24-34,共11页
This work demonstrates experimentally the close relation between return currents from relativistic laser-driven target polarization and the quality of the relativistic laser–plasma interaction for laser-driven second... This work demonstrates experimentally the close relation between return currents from relativistic laser-driven target polarization and the quality of the relativistic laser–plasma interaction for laser-driven secondary sources,taking as an example ion acceleration by target normal sheath acceleration.The Pearson linear correlation of maximum return current amplitude and proton spectrum cutoff energy is found to be in the range from~0.70 to 0.94.kA-scale return currents rise in all interaction schemes where targets of any kind are charged by escaping laser-accelerated relativistic electrons.Their precise measurement is demonstrated using an inductive scheme that allows operation at high repetition rates.Thus,return currents can be used as a metrological online tool for the optimization of many laser-driven secondary sources and for diagnosing their stability.In particular,in two parametric studies of laser-driven ion acceleration,we carry out a noninvasive online measurement of return currents in a tape target system irradiated by the 1 PW VEGA-3 laser at Centro de Láseres Pulsados:first the size of the irradiated area is varied at best compression of the laser pulse;second,the pulse duration is varied by means of induced group delay dispersion at best focus.This work paves the way to the development of feedback systems that operate at the high repetition rates of PW-class lasers. 展开更多
关键词 relativistic laser plasma interaction pearson linear correlation proton spectrum cutoff energy interaction schemes ion acceleration target normal sheath accelerationthe return current return currents
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Ionospheric F-region currents estimated from Macao Science Satellite-1 and Swarm satellite magnetic data 被引量:1
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作者 JuYuan Xu HongBo Yao Keke Zhang 《Earth and Planetary Physics》 2025年第3期731-739,共9页
Accurate modeling of Earth's ionospheric F-region currents is essential for refining geomagnetic field models and understanding magnetosphere-ionosphere coupling.In this study,we develop averaged models to charact... Accurate modeling of Earth's ionospheric F-region currents is essential for refining geomagnetic field models and understanding magnetosphere-ionosphere coupling.In this study,we develop averaged models to characterize F-region currents using magnetic data from the MSS-1(Macao Science Satellite-1) and Swarm satellite missions.Our approach employs a toroidal field representation,utilizing spherical harmonics to capture spatial variations and Fourier series to represent temporal dynamics.Two models,Model-A and Model-B,derived from distinct datasets,are constructed to represent current patterns at altitudes of 450 km and 512 km,respectively.Our models successfully capture the primary spatial structures and seasonal variations of polar field-aligned currents.Additionally,they accurately reproduce the localized inter-hemispheric field-aligned currents observed in mid and low latitudes during solstices,particularly between 14:00 and 16:00 magnetic local times.These findings enhance our understanding of ionospheric F-region currents and contribute to more precise geomagnetic field modeling. 展开更多
关键词 Macao Science Satellite-1 SWARM field-aligned currents GEOMAGNETISM ionosphere
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Giant Uncompensated Magnon Spin Currents in X-Type Magnets
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作者 Zi-An Wang Bo Li +7 位作者 Shui-Sen Zhang Wen-Jian Lu Mingliang Tian Yu-Ping Sun Evgeny Y.Tsymbal Kaiyou Wang Haifeng Du Ding-Fu Shao 《Chinese Physics Letters》 2025年第11期354-374,共21页
Magnon spin currents in insulating magnets are useful for low-power spintronics. However, in magnets stacked by antiferromagnetic(AFM) exchange coupling, which have recently aroused significant interest for potential ... Magnon spin currents in insulating magnets are useful for low-power spintronics. However, in magnets stacked by antiferromagnetic(AFM) exchange coupling, which have recently aroused significant interest for potential applications in spintronics, Bose–Einstein distribution populates magnon states across all energies from opposite eigenmodes, and hence the magnon spin current is largely compensated. Contrary to this common observation,here, we show that magnets with X-type AFM stacking, where opposite magnetic sublattices form orthogonal intersecting chains, support giant magnon spin currents with minimal compensation. Our model Hamiltonian calculations predict magnetic chain locking of magnon spin currents in these X-type magnets, significantly reducing their compensation ratio. In addition, the one-dimensional nature of the chain-like magnetic sublattices enhances magnon spin conductivities surpassing those of two-dimensional ferromagnets and canonical altermagnets. Notably, uncompensated X-type magnets, such as odd-layer antiferromagnets and ferrimagnets, can exhibit magnon spin currents polarized opposite to those expected by their net magnetization. These unprecedented properties of X-type magnets, combined with their inherent advantages resulting from AFM coupling, offer a promising new path for low-power high-performance spintronics. 展开更多
关键词 magnon spin currents giant magnon spin currents antiferromagnetic exchange coupling magnetic chain locking bose einstein distribution insulating magnets x type magnets
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Challenging Issues in Microplastic Transport by Submarine Turbidity Currents
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作者 Yang Lu Xiaolei Liu +3 位作者 Thorsten Stoesser Eckart Meiburg Dongfang Liang Xingsen Guo 《Journal of Earth Science》 2025年第4期1842-1847,共6页
0 INTRODUCTION Microplastics are defined as small plastic debris(1μm-5 mm),which have complex properties of widerange densities(0.05-2.3 g/cm^3),diverse shapes(e.g.,beads,fibers,foam and pellets)and low degradability... 0 INTRODUCTION Microplastics are defined as small plastic debris(1μm-5 mm),which have complex properties of widerange densities(0.05-2.3 g/cm^3),diverse shapes(e.g.,beads,fibers,foam and pellets)and low degradability(Harris,2020;Chubarenko et al.,2016). 展开更多
关键词 complex properties DEGRADABILITY TRANSPORT plastic debris m microplastics DENSITY submarine turbidity currents SHAPES
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Sun-Related Energy, Induced Ring, Auroral Electrojet and Magnetopause Currents Variability during Solar Cycles 23 and 24
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作者 Issamaïl Ki M’Bi Kaboré +1 位作者 Somaïla Koala Jean Louis Zerbo 《Journal of High Energy Physics, Gravitation and Cosmology》 2025年第1期110-119,共10页
In this study, we examined variability of sun-related energies, auroral electrojet current, ring current, and magnetopause current during solar cycles 23 and 24. The study revealed a dependence of sun-related energies... In this study, we examined variability of sun-related energies, auroral electrojet current, ring current, and magnetopause current during solar cycles 23 and 24. The study revealed a dependence of sun-related energies to the Sun and Earth currents systems with solar activity from 1996 to 2019. A decrease in the correlation between sun-related energies and sunspot number was observed over solar cycles 23 and 24 (0.88 for the solar cycle 23 and 0.66 for the solar cycle 24), with a drop in the speed of magnetic disturbances in the solar wind. These results could be attributed to the decrease in Sun’s magnetic field toroidal component magnitude induced by a weak in sunspots number and solar flares during the solar cycle 24. A weak in the Earth currents systems (auroral electrojet current, ring current, and magnetopause current) is also observed. During the decrease in the Earth currents, several peaks are observed, indicating a nonlinear dependence in the Earth currents variation (ring current, auroral electrojet current, and magnetopause current) from solar cycle 23 to solar cycle 24. This could be attributed to the Corotating Interaction Regions (CIRs) observed during the declining phase of solar cycle 23 and the deep minimum preceding solar cycle 24. 展开更多
关键词 Solar Activity Sun-Related Energy Corotating Interaction Region currents Systems
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Parasitic Shunt Currents in Alkaline Water Electrolysis (AWE) for Generating Clean Hydrogen
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作者 Tuhid Pashaee Golmarz Seyyed Kazem Yekani Ebrahim Abdi aghdam 《Energy Engineering》 2025年第10期4121-4134,共14页
Since the beginning of the 20th century,alkaline electrolysis has been used as a proven method for producing hydrogen on a megawatt scale.The existence of parasitic shunt currents in alkaline water electrolysis,which ... Since the beginning of the 20th century,alkaline electrolysis has been used as a proven method for producing hydrogen on a megawatt scale.The existence of parasitic shunt currents in alkaline water electrolysis,which is utilized to produce clean hydrogen,is investigated in this work.Analysis has been done on a 20-cell stack.Steel end plates,bipolar plates,and an electrolyte concentration of 6 M potassium hydroxide are all included in the model.The Butler-Volmer kinetics equations are used to simulate the electrode surfaces.Ohmic losses are taken into consideration in both the electrode and electrolyte phases,although mass transport constraints in the gas phase are not.Using an auxiliary sweep to solve equations,the model maintains an isothermal condition at 85℃ while adjusting the average cell voltage between 1.3 and 1.8 V.The results show that lower shunt currents in the outlet channels as opposed to the intake channels are the result of the electrolyte’s lower effective conductivity in the upper channels,which is brought on by a lower volume fraction of the electrolyte.Additionally,it has been seen that the shunt currents intensify as the stack gets closer to the conclusion.Efficiency is calculated by dividing the maximum energy output(per unit of time)that a fuel cell operating under comparable conditions might produce by the electrical energy needed to generate that output inside the stack.At first,energy efficiency increases due to the rise in coulombic efficiency,peaking around 1400 mA.The subsequent decline after reaching 1400 mA is linked to an increase in stack voltage at elevated current levels. 展开更多
关键词 Alkaline water electrolysis hydrogen production shunt current electric potential
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Terahertz time-domain spectroscopy to probe laser-excited spin currents in a Co/Gd system
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作者 Fan Zhang Bin Hong +6 位作者 Michel Hehn Rongqing Zhao Gregory Malinowski Yong Xu Stéphane Mangin Jon Gorchon Weisheng Zhao 《Chinese Physics B》 2025年第12期388-392,共5页
Single shot all-optical switching of the magnetization by femtosecond laser pulses in rare-earth transition-metal ferrimagnetic materials is particularly promising for future ultrafast magnetic storage applications.Mo... Single shot all-optical switching of the magnetization by femtosecond laser pulses in rare-earth transition-metal ferrimagnetic materials is particularly promising for future ultrafast magnetic storage applications.Moreover,ultrafast lasergenerated spin currents appear to play an important role in the switching process.Here,we try to separately detect the spin current from Gd in a Co/Gd bilayer system using terahertz time-domain spectroscopy.To this aim,we use different capping,buffer and embedded layers in order to tune the spin-to-charge and spin-current propagation and identify currents from each of the layers.We attribute the observed THz emission in all layers to the transition metal demagnetization induced spin currents,and detect no contribution from the Gd demagnetization.We attribute this absence of Gd-induced THz signal to the potentially slow demagnetization of Gd,which shift the emission spectra to lower frequencies,below our detection capabilities.These results highlight the limitations in using materials suffering from the so-called critical slowdown for the optimization of spintronic THz emitters. 展开更多
关键词 Co/Gd bilayer spin current THz emission DEMAGNETIZATION
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Morphology and Frictional Characteristics Under Electrical Currents of Al_2O_3/Cu Composites Prepared by Internal Oxidation 被引量:8
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作者 刘瑞华 宋克兴 +3 位作者 贾淑果 徐晓峰 郜建新 国秀花 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2008年第3期281-288,共8页
Two Al2O3/Cu composites containing 0.24 wt.% Al2O3 and 0.60 wt.% Al2O3 separately are prepared by internal oxidation. Effects of sliding speed and pressure on the frictional characteristics of the composites and coppe... Two Al2O3/Cu composites containing 0.24 wt.% Al2O3 and 0.60 wt.% Al2O3 separately are prepared by internal oxidation. Effects of sliding speed and pressure on the frictional characteristics of the composites and copper against brass are investigated and compared. The changes in morphology of the sliding surface and subsurface are examined with scanning electron microscope (SEM) and energy dispersive X-ray spectrum (EDS). The results show that the wear resistance of the Al2O3/Cu composites is superior to that of copper under the same conditions, Under a given electrical current, the wear rate of Al2O3/Cu composites decreases as the Al2O3-content increases, However, the wear rates of the Al2O3/Cu composites and copper increase as the sliding speed and pressure increase under dry sliding condition. The main wear mechanisms for Al2O3/Cu composites are of abrasion and adhesion; for copper, it is adhesion, although wear by oxidation and electrical erosion can also be observed as the speed and pressure rise. 展开更多
关键词 Al2O3/Cu composite internal oxidation friction and wear surface morphology current carder
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A study of impact of the reclamation and artificial island projects on tidal currents and sediment concentration in radial sand ridge field of the South Yellow Sea 被引量:3
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作者 赵强 何琴燕 +1 位作者 杨耀芳 黄秀清 《Marine Science Bulletin》 CAS 2015年第1期71-85,共15页
The two-dimensional hydrodynamic model, MIKE21, is applied to simulate the tidal currents and sediment concentration in the radial sand ridges of the South Yellow Sea. Results are in accordance with in situ observatio... The two-dimensional hydrodynamic model, MIKE21, is applied to simulate the tidal currents and sediment concentration in the radial sand ridges of the South Yellow Sea. Results are in accordance with in situ observations. Then the variations of tidal currents and suspended sediment concentration caused by reclamation and artificial islands projects are simulated. The results show that the impacts are limited around the project areas. After the projects, the fan-shaped, Jianggang centered tidal current pattern would be replaced by a pattern which is formed by two tidal paths. One locates at the Xiyang channel in north-south direction, and the other locates at the Huangshayang channel in east-west direction. The reclamation of Tiaozini separates the waters into south portion and north portion. The changes of sediment concentrations coincide with those of currents. Both the sediment concentrations and tidal currents increase at the northwest of Dongsha and the south of Gaoni, while both decrease at the north and south of Tiaozini, and the east and southwest of Dongsha. 展开更多
关键词 radial sand ridges RECLAMATION artificial island tidal currents suspended sediment concentration numerical modeling
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An Analysis of Observed Ocean Currents Data and Numerical Simulation in the Offshore Area of Jiaonan 被引量:3
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作者 刘伟峰 孙英兰 张学庆 《Marine Science Bulletin》 CAS 2006年第2期1-11,共11页
Based on the diurnal consecutively observed data in the offshore area of Jiaonan in 2005, the paper tries to make a preliminary analysis of the specificity of ocean currents, tidal current property and residual curren... Based on the diurnal consecutively observed data in the offshore area of Jiaonan in 2005, the paper tries to make a preliminary analysis of the specificity of ocean currents, tidal current property and residual current property in the area in observing dates. Then on the basis of observed data analysis and by employing the split-step method, the paper conducts a numerical simulation of the tidal current field, which can show the M2 tidal constituent tidal wave system, current ellipse distribution, maximum current velocity distribution and time-dependent current field. The calculated results agree well with the observed data, which can on the one hand reflect the basic specificities of temporal and spatial distribution of the M2 tidal constituent current field to some extent, and, on the other hand, offer more information about the hydrodynamic condition. So the paper would provide a scientific basis for the making of sea environment protection plans in the offshore area of Jiaonan under certain conditions. 展开更多
关键词 ocean currents observed data numerical calculation Jiaonan
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Ocean surface currents retrieval based on the satellite remote sensing data 被引量:1
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作者 安玉柱 陈奕德 +2 位作者 张韧 王辉赞 陈建 《Marine Science Bulletin》 CAS 2013年第2期46-58,共13页
The ocean surface currents are reconstructed from the satellite remote sensing data containing altimeter-derived sea surface height and QuikSCAT satellite-derived wind data. Based on the method proposed by Lagerloef, ... The ocean surface currents are reconstructed from the satellite remote sensing data containing altimeter-derived sea surface height and QuikSCAT satellite-derived wind data. Based on the method proposed by Lagerloef, a global weekly 0.5°×0.5°ocean surface current product was obtained over the period 2000 - 2008 by combining the geostrophic currents estimated from sea surface height with Ekman current estimated from the wind stress. Particularly, weight functions were introduced when calculating the Ekman currents to eliminate the discontinuity near 25°S and 25°N. These satellite-derived currents have been compared with TAO current meter and the SCUD product, respectively. The comparison showed that satellite-derived currents not only could capture the characteristics of ocean surface currents but also had high accuracy and reliability. The result showed that this innovatory method was effective. 展开更多
关键词 satellite altimeter data QuikSCAT wind field surface geostrophic current Ekman current
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Variations in tidal currents and suspended sediment concentration of the upper part of the North Channel of Changjiang Estuary over the past 10 years 被引量:1
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作者 刘高伟 程和琴 +3 位作者 计娜 乔远英 胡浩 王冬梅 《Marine Science Bulletin》 CAS 2015年第2期9-24,共16页
The tidal current duration (TCD) and velocity (TCV) and suspended sediment concentration (SSC) were measured in the dry season in December, 2011 and in the flood season in June, 2012 at the upper part of the Nor... The tidal current duration (TCD) and velocity (TCV) and suspended sediment concentration (SSC) were measured in the dry season in December, 2011 and in the flood season in June, 2012 at the upper part of the North Channel of Changjiang Estuary. They were assimilated with the measured data in 2003, 2004, 2006 and 2007, using the tidal range's proportion conversion. Variations in TCD and TCV, preferential flow and SSC have been calculated. Influences of typical engineering projects such as Qingcaosha fresh water reservoir, Yangtze River Bridge, and land reclamation on the ebb and flood TCD, TCV and SSC in the North Channel for the last 10 years are discussed. The results show that: (1) currently, in the upper part of North Channel, the ebb tide dominates; after the construction of the typical projects, ebb TCD and TCV tends to be larger and the vertical average ebb and flood SSC decrease during the flood season while SSC increases during the dry season; (2) changes in the vertical average TCV are mainly contributed by seasonal runoff variation during the flood season, which is larger in the flood season than that in the dry season; the controlling parameters of increasing ebb TCD and TCV are those large-scale engineering projects in the North Channel; variation in SSC may result mainly from the reduction of basin annual sediment loads, large-scale nearshore projects and so on. 展开更多
关键词 changes in tidal currents and suspended sediment concentration preferential flow data assimilation large-scale engineering projects Changjiang Estuary
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Analysis of tidal and residual currents across semi-enclosed bay mouth based on shipboard ADCP measurements 被引量:1
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作者 李希彬 孙晓燕 姚志刚 《Marine Science Bulletin》 2012年第2期37-45,共9页
Based on 25 hours shipboard ADCP measurements across semi-enclosed bay mouth(Kemen Channel), time series of tidal currents over 12 sites, which distribute evenly along the transect, were constructed to improve our u... Based on 25 hours shipboard ADCP measurements across semi-enclosed bay mouth(Kemen Channel), time series of tidal currents over 12 sites, which distribute evenly along the transect, were constructed to improve our understanding of tidal characteristics and residuals in this region. The tidal currents in Kemen Channel were identified as the regular semidiurnal and reversing tidal flows, with its behaviour more like standing waves. Moreover, the flood currents in the lower layers were found to be ahead of that in the upper layers and vice versa for ebb tides. The major of tidal ellipse for M2 constituent was found to be larger close to the southern side of the channel, with its incline also increasing toward the south. The signs of M4 constituent were also found mainly nearby the end points of this transect, indicating the importance of nonlinearity in tidal dynamics due to the shallower topography. A two-layer structure was found for the residual currents in Kemen Channel, flowing northeastwardly out of the Bay in upper 20m and southwestwardly into the bay in the lowers. Besides approximate 4.81×10^8 m^3 water exchanges were determined between the Luoyuan Bay and outer seas by the calculation of tidal flux through Kemen Channel. 展开更多
关键词 shipboard ADCP tidal currents RESIDUALS tidal transport
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Direct Tunneling Currents Through Gate Dielectrics in Deep Submicron MOSFETs 被引量:2
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作者 侯永田 李名复 金鹰 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2002年第5期449-454,共6页
A direct tunneling model through gate dielectric s in CMOS devices in the frame of WKB approximation is reported.In the model,an im proved one-band effective mass approximation is used for the hole quantization, wher... A direct tunneling model through gate dielectric s in CMOS devices in the frame of WKB approximation is reported.In the model,an im proved one-band effective mass approximation is used for the hole quantization, where valence band mixing is taken into account.By comparing to the experiments, the model is demonstrated to be applicable to both electron and hole tunneling c urrents in CMOS devices.The effect of the dispersion in oxide energy gap on the tunneling current is also studied.This model can be further extended to study th e direct tunneling current in future high-k materials. 展开更多
关键词 MOSFET direct tunneling current quantum effec t gate dielectrics
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Three-dimensional numerical simulation of tides and tidal currents in the Lianzhou Bay and adjacent areas
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作者 宋德海 鲍献文 +1 位作者 张少峰 张春华 《Marine Science Bulletin》 CAS 2013年第1期1-15,共15页
A 3-D unstructured-grid, finite-volume coastal ocean model (FVCOM) was used to study the tides and tidal currents in the Lianzhou Bay and adjacent areas. The simulation results were in good agreement with observatio... A 3-D unstructured-grid, finite-volume coastal ocean model (FVCOM) was used to study the tides and tidal currents in the Lianzhou Bay and adjacent areas. The simulation results were in good agreement with observations. The co-tidal maps of K1 , O1 , and M2 indicated that K1 and O1 were mostly standing waves outside the Lianzhou Bay, while M2 had a largely propagating character. However, all three constituents became propagating waves when entering the Lianzhou Bay, due to the shallow waters. The tidal current ellipses showed the characters of K1 , O1 , and M2 constituents: K1 and O1 were rotating outside the bay, but rectilinear along the water channels inside the bay; M2 was mostly rectilinear over the whole area. The tidal-induced residual current shows the flow was divided into two branches by the Guantouling Peninsula: one turned to flow west; the other was blocked by the southern boundary of the peninsula, creating a clockwise circulation. In Lianzhou Bay, there were two circulation systems, a cyclonic one at the top of the bay and an anti-cyclonic at the mouth. 展开更多
关键词 Lianzhou Bay FVCOM tide tidal current residual tidal current
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The Theory of Field-Effect Transistors:XI. The Bipolar Electrochemical Currents(1-2-MOS-Gates on Thin-Thick Pure-Impure Base)
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作者 薩支唐 揭斌斌 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2008年第3期397-409,共13页
The field-effect transistor is inherently bipolar, having simultaneously electron and hole surface and volume channels and currents. The channels and currents are controlled by one or more externally applied transvers... The field-effect transistor is inherently bipolar, having simultaneously electron and hole surface and volume channels and currents. The channels and currents are controlled by one or more externally applied transverse electric fields. It has been known as the unipolar field-effect transistor for 55-years since Shockley's 1952 invention,because the electron-current theory inevitably neglected the hole current from over-specified internal and boundary conditions, such as the electrical neutrality and the constant hole-electrochemical-potential, resulting in erroneous solutions of the internal and terminal electrical characteristics from the electron channel current alone, which are in gross error when the neglected hole current becomes comparable to the electron current, both in subthreshold and strong inversion. This report presents the general theory, that includes both electron and hole channels and currents. The rectangular ( x, y, z) parallelepiped transistors,uniform in the width direction (z-axis),with one or two MOS gates on thin and thick,and pure and impure base, are used to illustrate the two-dimensional effects and the correct internal and boundary conditions for the electric and the electron and hole electrochemical potentials. Complete analytical equations of the DC current-voltage characteristics of four common MOS transistor structures are derived without over-specification: the 1-gate on semi-infinite-thick impure-base (the traditional bulk transistor), the 1-gate on thin impure-silicon layer over oxide-insulated silicon bulk (SOI) ,the 1-gate on thin impure-silicon layer deposited on insulating glass (SOI TFT), and the 2-gates on thin pure-base (FinFETs). 展开更多
关键词 bipolar field-effect transistor theory MOS field-effect transistor simultaneous electron and hole surface and volume channels and currents surface potential two-section short-channel theory double-gate impure-base theory
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Topical administration of GLP-1 eyedrops improves retinal ganglion cell function by facilitating presynaptic GABA release in early experimental diabetes
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作者 Yu-Qi Shao Yong-Chen Wang +6 位作者 Lu Wang Hang-Ze Ruan Yun-Feng Liu Ti-Hui Zhang Shi-Jun Weng Xiong-Li Yang Yong-Mei Zhong 《Neural Regeneration Research》 2026年第2期800-810,共11页
Diabetic retinopathy is a prominent cause of blindness in adults,with early retinal ganglion cell loss contributing to visual dysfunction or blindness.In the brain,defects inγ-aminobutyric acid synaptic transmission ... Diabetic retinopathy is a prominent cause of blindness in adults,with early retinal ganglion cell loss contributing to visual dysfunction or blindness.In the brain,defects inγ-aminobutyric acid synaptic transmission are associated with pathophysiological and neurodegenerative disorders,whereas glucagon-like peptide-1 has demonstrated neuroprotective effects.However,it is not yet clear whether diabetes causes alterations in inhibitory input to retinal ganglion cells and whether and how glucagon-like peptide-1 protects against neurodegeneration in the diabetic retina through regulating inhibitory synaptic transmission to retinal ganglion cells.In the present study,we used the patch-clamp technique to recordγ-aminobutyric acid subtype A receptor-mediated miniature inhibitory postsynaptic currents in retinal ganglion cells from streptozotocin-induced diabetes model rats.We found that early diabetes(4 weeks of hyperglycemia)decreased the frequency of GABAergic miniature inhibitory postsynaptic currents in retinal ganglion cells without altering their amplitude,suggesting a reduction in the spontaneous release ofγ-aminobutyric acid to retinal ganglion cells.Topical administration of glucagon-like peptide-1 eyedrops over a period of 2 weeks effectively countered the hyperglycemia-induced downregulation of GABAergic mIPSC frequency,subsequently enhancing the survival of retinal ganglion cells.Concurrently,the protective effects of glucagon-like peptide-1 on retinal ganglion cells in diabetic rats were eliminated by topical administration of exendin-9-39,a specific glucagon-like peptide-1 receptor antagonist,or SR95531,a specific antagonist of theγ-aminobutyric acid subtype A receptor.Furthermore,extracellular perfusion of glucagon-like peptide-1 was found to elevate the frequencies of GABAergic miniature inhibitory postsynaptic currents in both ON-and OFF-type retinal ganglion cells.This elevation was shown to be mediated by activation of the phosphatidylinositol-phospholipase C/inositol 1,4,5-trisphosphate receptor/Ca2+/protein kinase C signaling pathway downstream of glucagon-like peptide-1 receptor activation.Moreover,multielectrode array recordings revealed that glucagon-like peptide-1 functionally augmented the photoresponses of ON-type retinal ganglion cells.Optomotor response tests demonstrated that diabetic rats exhibited reductions in visual acuity and contrast sensitivity that were significantly ameliorated by topical administration of glucagon-like peptide-1.These results suggest that glucagon-like peptide-1 facilitates the release ofγ-aminobutyric acid onto retinal ganglion cells through the activation of glucagon-like peptide-1 receptor,leading to the de-excitation of retinal ganglion cell circuits and the inhibition of excitotoxic processes associated with diabetic retinopathy.Collectively,our findings indicate that theγ-aminobutyric acid system has potential as a therapeutic target for mitigating early-stage diabetic retinopathy.Furthermore,the topical administration of glucagon-like peptide-1 eyedrops represents a non-invasive and effective treatment approach for managing early-stage diabetic retinopathy. 展开更多
关键词 diabetic retinopathy glucagon-like peptide-1 inhibitory synaptic transmission miniature inhibitory postsynaptic currents NEURODEGENERATION NEUROPROTECTION patch-clamp recording protein kinase C signaling pathway visual function
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Effects of noninvasive brain stimulation on motor functions in animal models of ischemia and trauma in the central nervous system
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作者 Seda Demir Gereon R.Fink +1 位作者 Maria A.Rueger Stefan J.Blaschke 《Neural Regeneration Research》 2026年第4期1264-1276,共13页
Noninvasive brain stimulation techniques offer promising therapeutic and regenerative prospects in neurological diseases by modulating brain activity and improving cognitive and motor functions.Given the paucity of kn... Noninvasive brain stimulation techniques offer promising therapeutic and regenerative prospects in neurological diseases by modulating brain activity and improving cognitive and motor functions.Given the paucity of knowledge about the underlying modes of action and optimal treatment modalities,a thorough translational investigation of noninvasive brain stimulation in preclinical animal models is urgently needed.Thus,we reviewed the current literature on the mechanistic underpinnings of noninvasive brain stimulation in models of central nervous system impairment,with a particular emphasis on traumatic brain injury and stroke.Due to the lack of translational models in most noninvasive brain stimulation techniques proposed,we found this review to the most relevant techniques used in humans,i.e.,transcranial magnetic stimulation and transcranial direct current stimulation.We searched the literature in Pub Med,encompassing the MEDLINE and PMC databases,for studies published between January 1,2020 and September 30,2024.Thirty-five studies were eligible.Transcranial magnetic stimulation and transcranial direct current stimulation demonstrated distinct strengths in augmenting rehabilitation post-stroke and traumatic brain injury,with emerging mechanistic evidence.Overall,we identified neuronal,inflammatory,microvascular,and apoptotic pathways highlighted in the literature.This review also highlights a lack of translational surrogate parameters to bridge the gap between preclinical findings and their clinical translation. 展开更多
关键词 noninvasive brain stimulation preclinical modeling STROKE transcranial direct current stimulation transcranial magnetic stimulation traumatic brain injury
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Numerical study of the tides and residual currents in the Qiongzhou Strait 被引量:9
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作者 陈长霖 李培良 +3 位作者 侍茂崇 左军成 陈美香 孙海萍 《Chinese Journal of Oceanology and Limnology》 SCIE CAS CSCD 2009年第4期931-942,共12页
Based on the three-dimensional ECOM model,the tide,tide-induced residual current,wind-driven and density currents in the Beibu (Tonkin) Gulf and Qiongzhou Strait are diagnostically computed in fine grid.The tides and ... Based on the three-dimensional ECOM model,the tide,tide-induced residual current,wind-driven and density currents in the Beibu (Tonkin) Gulf and Qiongzhou Strait are diagnostically computed in fine grid.The tides and tidal currents in the Beibu Gulf and Qiongzhou Strait are well reproduced.The model results show that the semidiurnal tidal wave propagates eastward from the Beibu Gulf through Qiongzhou Strait,while diurnal tidal waves enter the strait from both the eastern and western sides and interact on the southeast coast of the strait.The formation processes of the residual currents in Qiongzhou Strait in summer (August) and winter (January) are mainly discussed.It is shown that the total residual currents (coupling effect of wind,tide and density) in the strait are westward in both summer and winter.The water volume transported from the east to west into the Beibu Gulf is 0.026 Sv in summer and 0.116 Sv in winter.Numerical experiments indicate that the dominant factor affecting the residual currents in the strait is not the wind stress but the tidal rectification.The westward tide-induced residual current,driven by the tidal rectification,is rather strong in the strait with water volume transport of 0.063 Sv.The wind in summer only reduces the westward tide-induced residual current to a certain extent,and the wind in winter approximately doubles the westward tide-induced residual current through the strait.The density current contributes little to the total residual current in both summer and winter. 展开更多
关键词 numerical models TIDES residual currents wind-driven currents South China Sea QiongzhouStrait
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