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A New Approach to High-Order Boussinesq-Type Equations with Ambient Currents 被引量:5
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作者 王亚玲 张洪生 +1 位作者 缪国平 朱良生 《China Ocean Engineering》 SCIE EI 2005年第1期49-60,共12页
A new approach to high-order Boussinesq-type equations with ambient currents is presented. The current velocity is assumed to be uniform over depth and of the same magnitude as the shallow water wave celerity. The wav... A new approach to high-order Boussinesq-type equations with ambient currents is presented. The current velocity is assumed to be uniform over depth and of the same magnitude as the shallow water wave celerity. The wave velocity field is expressed in terms of the horizontal and vertical wave velocity components at an arbitrary water depth level. Linear operators are introduced to improve the accuracy of the kinematic condition at the sea bottom. The dynamic and kinematic conditions at the free surface are expressed in terms of wave velocity variables defined directly on the free surface. The new equations provide high accuracy of linear properties as well as nonlinear properties from shallow to deep water, and extend the applicable range of relative water depth in the case of opposing currents. 展开更多
关键词 Boussinesq-type equations wave-current interaction dispersion properties shoaling characteristics nonlinear properties Padé approximation
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Connexin 43 co-locolizes and regulates the L type calcium channel current in atrial myocytes
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作者 饶芳 薛玉梅 +9 位作者 邓春玉 余细勇 肖定璋 陈少贤 林秋雄 杨慧 邝素娟 刘晓颖 朱杰宁 吴书林 《South China Journal of Cardiology》 CAS 2015年第2期114-121,共8页
Background Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia without effective treatment. AF is associated with atrial conduction disturbances caused by electrical and / or structural remodeli... Background Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia without effective treatment. AF is associated with atrial conduction disturbances caused by electrical and / or structural remodeling. But the role of connexin (Cx) 43 in the regulation of L type calcium channel (LCC) remains unclear. We hypothesized that Cx 43 might co-localize and regulate the L type calcium channel current (ICa, D. Methods Real-time PCR and whole-cell patch clamp were used to detect the expression of LCC lc subunit and the cur rent density of Ica, L, before and after Cx 43 knocking down respectively. The co-localization of Cx 43 with LCC was investigated by co-immunoprecipitation and confocal microscopy. Results Knocking down of Cx43 significantly inhibited the current density of ICa, L through decreasing the gene expression of LCC alc in cul tured atrium-derived myocytes (HL-1 cells). Cx43 co-localized with LCC eric subunit in atrial myocytes. Conclusions Cx 43 regulates the ICa, L in atrial myoctyes through LCC, representing a potential pathogenic mechanism in atrial arrhythmias. 展开更多
关键词 connexin 43 L type calcium channel current HL-1 cells atrial fibrillation
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Study on the Effect of Multi-Type Current Transformers Hybrid Operation on Differential Protection of the Bus Based on Dynamic Simulation
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作者 Wenbiao Liao Zexin Zhou +2 位作者 Rongrong Zhan Yanjun Li Zhengguang Chen 《Energy and Power Engineering》 2017年第4期1-11,共11页
This paper analyzes characteristics of multi type current transformers hybrid operation for each branch of the bus and their effects on differential protection of the bus. By theoretically analyzing transmission chara... This paper analyzes characteristics of multi type current transformers hybrid operation for each branch of the bus and their effects on differential protection of the bus. By theoretically analyzing transmission characteristics of multi type current transformers and their influence factors, we study the dynamic model testing method of multi type current transformers for the bus, and design 3 kinds of testing schemes by making the equivalent model based on the field of P-level current transformer, TPY-level current transformer and electronic current transformer, and build the hybrid operation testing platform of multi type current transformers. Finally, we compare and analyze the transmission characteristics difference of multi type current transformers on the same branch and the characteristics difference of hybrid operation in two successive external faults, analyze the cause behind the differences, and put forward the corresponding improvement measures. 展开更多
关键词 DIFFERENTIAL Protection of the BUS Multi-type current Transformer Hybrid Operation DYNAMIC SIMULATION TEST Method DYNAMIC SIMULATION TEST PLATFORM
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The Effect of Extrogenous Phosphocreatine on L-type Calcium Current in Ischemic Guinea Pig Ventricular Myocytes
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作者 时向民 李天德 +2 位作者 杨庭树 王玉堂 单兆亮 《South China Journal of Cardiology》 CAS 2005年第2期72-76,共5页
Objectives Heart failure (HF) is one of the most common outcome for all kinds of heart diseases, the effects of energetic therapy on HF remains controversial, especially to ischemic HF. The aim of this study was to ... Objectives Heart failure (HF) is one of the most common outcome for all kinds of heart diseases, the effects of energetic therapy on HF remains controversial, especially to ischemic HF. The aim of this study was to explore the effect of exogenous phosphocreatine with different concentration on L-type calcium(I Cc-L) current in ischemic ventricular myocytes of guinea pig and to investigate its underlying electrophysiological mechanism for the treatment of ischemic HF. Methods Single ventricular myocytes were isolated enzymatically from left ventricle of guinea pig. Peak I Ca-L current were recorded using patch clamp techniques in the whole-cell configuration when myocytes had been superfused with normal Tyrode solution, simple ischemic solution, ischemic solution containing phosphocreatine with different concentration for 10 minutes respectively. Results Peak I Ca-L current density of myocytes superfused with simple simulated ischemic solution was remarkably inhibited by 80.6 ± 5.2% compared with myocytes superfused with normal Tyrode solution(P〈0.05). Ischemic solution containing phosphocreatine of 5, 10, 20, 30mmol/L inhibited Peak I Ca-L current density by (53.8±6.7)%, (41.8 ± 8.2)%, (38.1±7.4)%, (36.6±9.7)% respectively. There was no statistical significance among phosphocreation of 10, 20, 30 mmol / L. Conclusions Extrogenous phosphocreatine could reverse the inhibition of I Ca-L current under ischemic condition, which could be the ionic basis for the treatment of ischemic heart failure. 0-10 mmol/L phosphocreatine exerted significant dose-effect relationship which no longer existed as concentration more than 10 mmol/L. It is supposed that phosphocreatine increased I Ca-L current by many pathways rather than simple substrate for ATP synthesis. 展开更多
关键词 Patch clamp L-type calcium current Ischemia heart failure Phosphocreatine
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A Novel Crowbar Impulse Current Circuit for Testing the Switch-Type SPD 被引量:1
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作者 姚学玲 陈景亮 孙伟 《Plasma Science and Technology》 SCIE EI CAS CSCD 2008年第2期221-226,共6页
A crowbar impulse current circuit for testing the switch-type surge protective device (SPD) is presented. The crowbar circuit consists of a computer control circuit, a trigger voltage pulse generator, a main dischar... A crowbar impulse current circuit for testing the switch-type surge protective device (SPD) is presented. The crowbar circuit consists of a computer control circuit, a trigger voltage pulse generator, a main discharging switch, and a crowbar pseudospark switch. The active trigger technology was studied in the crowbar impulse current circuit. The circuit monitors the main discharging current and generates a trigger signal at a proper time for the crowbar pseudospark switch operation. The trigger characteristics of the main discharge switch and the crowbar pseu- dospark switch were investigated. By monitoring the preset applied capacitor voltage, the gap distance of the main discharging switch could be adjusted to ensure a discharging delay time less than 2 μs. Equipped with a surface ttashover trigger device made of high relative perimittivity dielectric material BaTiO3 (εr = 3460), the discharge delay time of the crowbar pseudospark switch is less than 85 ns, and the minimum operating voltage is less than 1% of its self-breakdown voltage. With a storage capacitor of 9 μF , an inductor of 18 μH and a crowbar pseudospark switch, a load of 30 mΩ and an applied capacitor voltage of 40 kV, an impulse current waveform of maximum 25 kA was generated with a rise time and time to half peak value of 17.2 μs and 336μs respectively. 展开更多
关键词 crowbar impulse current circuit triggered crowbar pseudospark switch activetrigger technology switch-type surge protective device
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单开关耦合电感倍压型组合拓扑变换器
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作者 荣德生 邢雪 孙瑄瑨 《电力系统及其自动化学报》 北大核心 2026年第1期42-50,共9页
为解决直流变换器在高压应用场景中增益不足与效率受限的瓶颈问题,基于耦合电感倍压技术提出一种新型组合拓扑结构的DC/DC变换器。该方案融合Boost与Sepic电路结构优势,引入耦合电感倍压单元及无源钳位网络构建电流输入型架构,在保证输... 为解决直流变换器在高压应用场景中增益不足与效率受限的瓶颈问题,基于耦合电感倍压技术提出一种新型组合拓扑结构的DC/DC变换器。该方案融合Boost与Sepic电路结构优势,引入耦合电感倍压单元及无源钳位网络构建电流输入型架构,在保证输入电流连续的情况下还可实现漏感能量回收与全开关器件零电流开通。对变换器工作原理进行了详细分析,并提供了其在连续模式下的性能参数及临界条件。结果表明,新拓扑具备高电压增益与低电压应力优势。此外,实验搭建200 W原理样机,验证了变换器的高效运行特性,并有效支撑了理论分析的准确性。 展开更多
关键词 耦合电感 高增益 电流输入型 无源钳位 零电流开关
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电阻型超导限流器的限流和恢复特性仿真分析研究
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作者 张琦 项彬 +5 位作者 马舒幸 邓朴达 袁仲滨 耿英三 刘志远 王建华 《西安交通大学学报》 北大核心 2026年第2期156-165,共10页
为进一步探索超导限流器的恢复性能,准确判断其恢复状态,对电阻型超导限流器的限流电阻和恢复特性进行了仿真分析研究。基于实验获得的ST-12-L超导带材单位电阻-单位热量(R-Q)拟合曲线,以及超导的电场强度-电流密度指数(E-J)公式,结合... 为进一步探索超导限流器的恢复性能,准确判断其恢复状态,对电阻型超导限流器的限流电阻和恢复特性进行了仿真分析研究。基于实验获得的ST-12-L超导带材单位电阻-单位热量(R-Q)拟合曲线,以及超导的电场强度-电流密度指数(E-J)公式,结合液氮相变传热方程,在SIMULINK中建立了电阻型超导限流器的R-Q恢复模型和E-J恢复模型;仿真分析了LC短路电流下ST-12-L超导带材的故障限流和恢复特性;基于LC源和恢复测试回路,搭建了并联超导带材的限流和恢复实验电路,进行了LC短路冲击下的超导带材的失超限流和恢复测试,并将实验结果和仿真结果进行了对比。对比发现:在限流效果仿真中,E-J恢复模型的电流正、负峰值与实验的最大误差分别为3.6%和15%,而R-Q恢复模型的电流正、负峰值与实验值的最大误差分别为2.3%和8.6%,R-Q恢复模型的限流仿真更为准确;在恢复时间仿真中,R-Q恢真模型的恢复时间最大误差仅为0.120 s,误差远小于E-J恢复模型的仿真结果。R-Q恢复仿真模型能有效模拟超导带材的失超和恢复,促进电阻型超导限流器在电力系统中的应用。 展开更多
关键词 电阻型超导限流器 超导仿真 限流电阻 恢复特性
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开关柜CT过热绝缘故障引起变压器停电的原因分析
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作者 咸日明 张璟烁 +2 位作者 咸日常 赵如杰 郑小刚 《变压器》 2026年第2期60-66,共7页
本文作者介绍夏季高温、高负荷条件下,变电站开关柜CT过热绝缘损伤故障及相关设备异常发热的处理案例与应急措施。结合现场设备实际运行工况和继电保护装置动作情况,通过对10 kV开关柜内干式电流互感器的绝缘检查与试验,阐明开关柜CT发... 本文作者介绍夏季高温、高负荷条件下,变电站开关柜CT过热绝缘损伤故障及相关设备异常发热的处理案例与应急措施。结合现场设备实际运行工况和继电保护装置动作情况,通过对10 kV开关柜内干式电流互感器的绝缘检查与试验,阐明开关柜CT发生过热绝缘损伤故障,一次回路电流窜入二次保护回路,造成变压器差动速断保护动作;对存在重大过热隐患的运行设备,采取负荷转移、温度监视和紧急强制散热措施,化解恶性停电风险。提出优化配网运行方式、重视变电站设备降温、合理选择CT变比等三个方面的防范措施,对变电设备高温运行的应急处置具有警示和现实借鉴意义。 展开更多
关键词 干式电流互感器 绝缘故障 变压器停电
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电容器组寄生电容致初始电流失衡机理与抑制技术
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作者 赵彦军 魏文文 +1 位作者 杨银合 邱晓峰 《电力电容器与无功补偿》 2026年第1期28-34,共7页
本文针对某高压滤波电容器组桥式差电流保护验收试验异常展开研究。分析表明,台架奇数串电容器布置导致固定电位点两侧寄生电容不对称,引发耦合电流偏差使不平衡电流超标。提出调整主电容与寄生电容调平两种方案,后者因施工周期短、成... 本文针对某高压滤波电容器组桥式差电流保护验收试验异常展开研究。分析表明,台架奇数串电容器布置导致固定电位点两侧寄生电容不对称,引发耦合电流偏差使不平衡电流超标。提出调整主电容与寄生电容调平两种方案,后者因施工周期短、成本低更具优势。通过量化分析不同层位固定电位点调整对不平衡电流的影响,筛选优化方案并现场验证,调整电容器层间固定电位点布置可均衡寄生电容分布,使不平衡电流达标。研究创新提出寄生电容调平技术,经理论与实践验证,为高压直流输电工程用电容器组不平衡保护调试提供可复制技术方案,兼具显著工程效益与应用价值。 展开更多
关键词 电容器组 寄生电容 电容耦合电流 桥式差电流保护
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铁磁性双夹套管式压力容器脉冲涡流检测方法的可行性分析
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作者 孙杰 区子浩 +2 位作者 陈俊仰 李绪丰 付跃文 《中国特种设备安全》 2026年第2期23-27,共5页
铁磁性双夹套管式压力容器常应用于大型石油化工装置,从外夹套管检测其内管部位历来是一项工程技术难题。本研究基于脉冲涡流检测技术,通过建立仿真模型,设计一种圆柱形检测探头,得到合适的激励参数、电压衰减信号特征以及内管涡流分布... 铁磁性双夹套管式压力容器常应用于大型石油化工装置,从外夹套管检测其内管部位历来是一项工程技术难题。本研究基于脉冲涡流检测技术,通过建立仿真模型,设计一种圆柱形检测探头,得到合适的激励参数、电压衰减信号特征以及内管涡流分布状态。通过试验进行可行性验证,验证了采用目前的脉冲涡流检测技术可在外夹套名义壁厚10 mm、两钢板间距12 mm的条件下,可对内管的外壁局部腐蚀减薄缺陷实现有效检出。同时,结论表明:今后应围绕探头结构及抗干扰去噪等方向开展进一步的深入研究。 展开更多
关键词 铁磁性 双夹套管式 脉冲涡流检测 探头 腐蚀
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基于CiteSpace的浮针疗法可视化分析及优势病种研究现状
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作者 齐志华 张锡玮 《中国中医药图书情报杂志》 2026年第1期96-100,共5页
目的探讨浮针临床应用的热点及前沿趋势,以及其优势病种的临床研究进展与机制探索成果。方法检索中国知识资源总库(CNKI)、中国学术期刊数据库(万方数据)、中文科技期刊数据库(VIP)1997年1月1日-2025年3月7日浮针临床研究文献,利用CiteS... 目的探讨浮针临床应用的热点及前沿趋势,以及其优势病种的临床研究进展与机制探索成果。方法检索中国知识资源总库(CNKI)、中国学术期刊数据库(万方数据)、中文科技期刊数据库(VIP)1997年1月1日-2025年3月7日浮针临床研究文献,利用CiteSpace6.3.R1软件进行作者、机构、关键词可视化分析。结果共纳入文献1306篇,浮针临床研究发文量总体呈上升趋势。发文较多机构为广州中医药大学、广东省第二中医院、黑龙江中医药大学;发文较多的作者为符仲华、陆瑾、李新伟;高频关键词为“临床疗效”“疼痛”“针刺疗法”“肩周炎”“脑卒中”;突现分析显示,痹证、生活质量和腰椎功能是近年研究热点。结论浮针临床研究团队内部和同地区机构合作密切,但团队间和跨地区合作较少,今后尚需建立合作。痹证和脑卒中是浮针疗法的优势病种,制定更完备的临床疗效标准、设计更规范的临床试验及结合中医辨证论治可能是浮针临床研究趋势。 展开更多
关键词 浮针疗法 研究现状 优势病种 文献计量学 可视化分析
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T型三电平逆变器混合脉冲宽度调制相电流重构策略
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作者 申永鹏 郭海东 +3 位作者 刘普 刘刚 孙健 王延峰 《电力系统保护与控制》 北大核心 2026年第1期94-104,共11页
针对T型三电平逆变器传统空间矢量脉冲宽度调制方法存在的中点电流不可观测区域问题,提出了T型三电平逆变器混合脉冲宽度调制相电流重构策略。首先,该策略分析了中点电流的采样机制以及不可观测区域的形成机理,并依据最小采样时间对不... 针对T型三电平逆变器传统空间矢量脉冲宽度调制方法存在的中点电流不可观测区域问题,提出了T型三电平逆变器混合脉冲宽度调制相电流重构策略。首先,该策略分析了中点电流的采样机制以及不可观测区域的形成机理,并依据最小采样时间对不可观测区域进行分类。其次,基于伏秒平衡和合成零矢量原理,通过在不可观测区域插入不同的补偿电压矢量,从而对可观测电压矢量的可观测时长进行补偿。同时,该策略调整了原有的开关序列,以抵消补偿电压矢量的作用效果,进而确保目标电压矢量的大小和方向维持不变。最终,该策略消除了中点电流的不可观测区域,实现了中点电流的稳定、准确检测。实验结果表明,所提方法能够实现三相电流的完全重构,相电流总谐波畸变率低于3.30%。 展开更多
关键词 T型三电平逆变器 中点电流 相电流重构 不可观测区域 电压矢量
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Current Gold Prospecting in China 被引量:1
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作者 LEI Shibin QING Min +1 位作者 NIU Cuiyi WANG Liang 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2016年第4期1298-1320,共23页
In China, there are 12 types of gold deposits in 57 class-Ill metallogenic zones, formed in 7 main metaUogenic periods. Most gold deposits are small or occur as ore spots; very large deposits are rare with relatively ... In China, there are 12 types of gold deposits in 57 class-Ill metallogenic zones, formed in 7 main metaUogenic periods. Most gold deposits are small or occur as ore spots; very large deposits are rare with relatively poor quality, mainly medium to low grade. Only 35% of the total gold reserves is identified, while a large amount of reserves is yet to be identified. In recent years, China Geological Survey has organized or conducted mineral resources survey and evaluation project, replacement resources prospecting for deposits in crisis, old mines prospecting and commercial prospecting funded or encouraged by the Central Government. These efforts have been fruitful. According to the temporal and spatial allocation of gold resources, and experiences from recent prospecting efforts, western China and the deep layers and peripheries of the-sits in eastern China have relatively high prospecting potential. The government should give even more support to the gold industry and strengthen technological innovation to help address difficulties in gold exploitation and processing. The government should also formulate consistent plans, consolidate mining rights, and promote integrated exploration, so as to achieve new major breakthroughs in gold prospecting. Gold is both a form of material wealth and a way of storing wealth. It is a rare resource with dual functions of commodity and currency. As an important global strategic asset and a cornerstone of financial reserves, gold plays an irreplaceable role in securing national economic development, maintaining financial security, strengthening national comprehensive power and promoting RMB internationalization. Based on latest research and prospecting results, the thesis proposes preliminary conclusions on types, temporal and spatial allocation, and exploration and development of gold deposits in China; predicts China's gold resource potential; reviews recent gold prospecting and exploration efforts; and, in the hope of offering some reference for the new round of gold prospecting, exploration and planning, offers some suggestions. 展开更多
关键词 China gold resource metallogenic type current situation
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Investigation and Analysis on Current Situation of Coal-Burning Fluorosis Prevalence 被引量:2
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作者 Wei Yan Jun Xie +3 位作者 Xinshu Li Yalin Chen Wenli Huang Shuang Zhou 《Open Journal of Epidemiology》 2017年第2期115-123,共9页
Objective: The purpose of the paper is to provide the result from investigation on the current situation of coal-burning fluorosis prevalence in Chongqing City and make an assessment on the prevention and curing measu... Objective: The purpose of the paper is to provide the result from investigation on the current situation of coal-burning fluorosis prevalence in Chongqing City and make an assessment on the prevention and curing measures. Method: The Dean’s Method is applied to investigate on the fluorotic teeth of locally-born children aged between 8 to 12;investigate how modified cooking stoves are utilized by households and how food maize and hot pepper are being dried;and test the urinary fluorine content and pepper fluorine content. Result: The investigations show that, in the 661 villages with illness history from the 100 townships of 13 districts in Chongqing City, 11.28% (7464/ 66,162) of the children aged between 8 and 12 suffer from dental fluorosis;the stoves modified rate, qualified rate of modified stoves, and correct utilization rate of qualified modified stoves are respectively 100%, 98.82%, and 99.45%;and food maize and hot pepper’s drying rates are respectively 99.88% and 99.75%. Conclusion: The result shows that the coal-burning type fluorosis prevalence in the endemic area of Chongqing City has decreased dramatically, the preventive measure is effectively implemented, and a long-term preventive mechanism has preliminarily been established. 展开更多
关键词 Coal-Burning type FLUOROSIS current PREVALENCE CONDITIONS
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波畸变背景下构网型储能变流器并网系统混合调制控制研究
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作者 王绪利 杨欣 +3 位作者 李志伟 施天成 周帆 侯四维 《电气自动化》 2026年第1期40-42,45,共4页
针对储能变流器在提供惯量支撑的过程中产生功率振荡等问题,提出谐波畸变背景下构网型储能变流器并网系统混合调制控制方法。利用自回归积分滑动平均模型预测未来一段时间内并网电流并计算与参考电流之间的误差,建立由总谐波畸变率和误... 针对储能变流器在提供惯量支撑的过程中产生功率振荡等问题,提出谐波畸变背景下构网型储能变流器并网系统混合调制控制方法。利用自回归积分滑动平均模型预测未来一段时间内并网电流并计算与参考电流之间的误差,建立由总谐波畸变率和误差绝对值积分组成的目标函数;利用粒子群算法求取目标函数,得出线性控制器最优参数;基于参数优化后的线性控制器设计混合调制控制方法,通过误差计算控制信号和空间矢量脉宽调制进行混合调制。结果表明:所采用的控制策略有效地抑制了功率波动,提高了并网系统的稳定性和可靠性。 展开更多
关键词 谐波畸变背景 构网型储能变流器 并网系统电流 线性控制器 混合调制控制方法
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基于实用短路电流计算的配电网低压开关整定值设定方法
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作者 成宏亮 吴思玥 蔡徐平 《建筑电气》 2026年第2期42-46,共5页
基于低压配电网短路电流计算模型对单相接地和三相接地分别进行短路电流计算。根据现有整定原则,建立一套基于实用短路电流计算的配电网低压开关整定值设定方法。最后,在考虑出线电缆长度及截面积变化的基础上,对实际配电站、箱变低压... 基于低压配电网短路电流计算模型对单相接地和三相接地分别进行短路电流计算。根据现有整定原则,建立一套基于实用短路电流计算的配电网低压开关整定值设定方法。最后,在考虑出线电缆长度及截面积变化的基础上,对实际配电站、箱变低压开关进行整定计算,提出可执行的方法。 展开更多
关键词 低压开关 整定值设定 短路电流 配电网 配电站 箱变 低压电缆
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The Continuation Power Flow Considering Both Generator Excitation Current Limits and Armature Current Limits 被引量:4
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作者 ZHAO Jinquan QIAN Tianneng 《中国电机工程学报》 EI CSCD 北大核心 2012年第22期I0016-I0016,10,共1页
在传统连续潮流算法中,发电机无功限制采用定上、下限值来处理,随着有功负荷增加,无功限值通常不变,得到的电压稳定裕度偏大。根据同步发电机的无功出力特性,提出同时计及发电机励磁电流约束和电枢电流约束的连续潮流模型和方法。当相... 在传统连续潮流算法中,发电机无功限制采用定上、下限值来处理,随着有功负荷增加,无功限值通常不变,得到的电压稳定裕度偏大。根据同步发电机的无功出力特性,提出同时计及发电机励磁电流约束和电枢电流约束的连续潮流模型和方法。当相应参数越限时,将发电机节点转换为励磁恒定模型或者电枢电流恒定模型进行计算。所提PV、PEq、PIa节点类型双向转换逻辑可在潮流迭代内进行发电机限制模式的转换,模拟实际系统无功能力的变化。分岔点类型识别模块可以识别崩溃点类型及关键约束。通过新英格兰39节点算例的仿真,证明所提算法是有效的。 展开更多
关键词 发电机励磁 连续潮流 电枢电流 电流限制 功率限制 负荷裕度 稳定评估 CPF
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Effect of gingerol on colonic motility via inhibition of calcium channel currents in rats 被引量:1
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作者 Zheng-Xu Cai Xu-Dong Tang +4 位作者 Feng-Yun Wang Zhi-Jun Duan Yu-Chun Li Juan-Juan Qiu Hui-Shu Guo 《World Journal of Gastroenterology》 SCIE CAS 2015年第48期13466-13472,共7页
AIM: To investigate the effect of gingerol on colonic motility and the action of L-type calcium channel currents in this process.METHODS: The distal colon was cut along the mesenteric border and cleaned with Ca^(2+)-f... AIM: To investigate the effect of gingerol on colonic motility and the action of L-type calcium channel currents in this process.METHODS: The distal colon was cut along the mesenteric border and cleaned with Ca^(2+)-free physiological saline solution. Muscle strips were removed and placed in Ca^(2+)-free physiological saline solution, which was oxygenated continuously. Longitudinal smooth muscle samples were prepared by cutting along the muscle strips and were then placed in a chamber. Mechanical contractile activities of isolated colonic segments in rats were recorded by a 4-channel physiograph. Colon smooth muscle cells were dissociated by enzymatic digestion. L-type calcium currents were recorded using the conventional whole-cell patch-clamp technique.RESULTS: Gingerol inhibited the spontaneous contraction of colonic longitudinal smooth muscle in a dose-dependent manner with inhibition percentages of 13.3% ± 4.1%, 43.4% ± 3.9%, 78.2% ± 3.6% and 80.5% ± 4.5% at 25 μmol/L, 50 μmol/L, 75 μmol/L and 100 μmol/L, respectively(P < 0.01). Nifedipine, an L-type calcium channel blocker, diminished the inhibition of colonic motility by gingerol. Gingerol inhibited L-type calcium channel currents in colonic longitudinal myocytes of rats. At a 75 μmol/L concentration of gingerol, the percentage of gingerolinduced inhibition was diminished by nifedipine from 77.1% ± 4.2% to 42.6% ± 3.6%(P < 0.01). Gingerol suppressed IBa in a dose-dependent manner, and the inhibition rates were 22.7% ± 2.38%, 35.77% ± 3.14%, 49.78% ± 3.48% and 53.78% ± 4.16% of control at 0 m V, respectively, at concentrations of 25 μmol/L, 50 μmol/L, 75 μmol/L and 100 μmol/L(P < 0.01). The steady-state activation curve was shifted to the right by treatment with gingerol. The value of half activation was-14.23 ± 1.12 m V in the control group and-10.56 ± 1.04 m V in the 75 μmol/L group(P < 0.05) with slope factors, Ks, of 7.16 ± 0.84 and 7.02 ± 0.93(P < 0.05) in the control and 75 μmol/L groups, respectively. However, the steady-state inactivation curve was not changed, with a half-inactivation voltage, 0.5 V, of-27.43 ± 1.26 m V in the control group and-26.56 ± 1.53 m V in the 75 μmol/L gingerol group(P > 0.05), and a slope factor, K, of 13.24 ± 1.62 in the control group and 13.45 ± 1.68(P > 0.05) in the 75 μmol/L gingerol group.CONCLUSION: Gingerol inhibits colonic motility by preventing Ca^(2+) influx through L-type calcium channels. 展开更多
关键词 GINGEROL COLONIC MOTILITY L-type calciumchannel current Spontaneous CONTRACTION Longitudinalsmooth muscle MYOCYTES
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A Numerical Model for Nonlinear Wave Propagation on Non-uniform Current 被引量:2
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作者 张洪生 王卫远 +2 位作者 冯文静 杨建民 卢士强 《China Ocean Engineering》 SCIE EI 2010年第1期15-28,共14页
On the basis of the new type Boussinesq equations (Madsen et al., 2002), a set of equations explicitly including the effects of currents on waves are derived. A numerical implementation of the present equations in o... On the basis of the new type Boussinesq equations (Madsen et al., 2002), a set of equations explicitly including the effects of currents on waves are derived. A numerical implementation of the present equations in one dimension is described. The numerical model is tested for wave propagation in a wave flume of uniform depth with current present. The present numerical results are compared with those of other researchers. It is validated that the present numerical model can reasonably reflect the nonlinear influences of currents on waves. Moreover, the effects of inputting different incident boundary conditions on the calculated results are studied. 展开更多
关键词 Boussirtesq-type equations numerical model wave-current interaction dispersion relation incident bound-ary cortdhion
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Study on a cold-cathode H^- PIG-type ion source 被引量:4
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作者 LONG Jidong YANG Zhen +2 位作者 DONG Pan HE Xiaozhong ZHANG Kaizhi 《Nuclear Science and Techniques》 SCIE CAS CSCD 2013年第4期1-4,共4页
A cold-cathode Penning Ion Gauge(PIG) type ion source as the internal ion source of an 11 MeV cyclotron is designed and tested at Institute of Fluid Physics.The design considerations and some testings are presented.Ex... A cold-cathode Penning Ion Gauge(PIG) type ion source as the internal ion source of an 11 MeV cyclotron is designed and tested at Institute of Fluid Physics.The design considerations and some testings are presented.Experimental results of Balmer-line-Emission show that the discharge characteristic,which is mainly determined by gas-flow rate,is not very sensitive to arc current and magnetic field in the operation ranges of the cyclotron.The arc power decreases and ascends while the gas-flow rate goes up from 0.5 SCCM to 20 SCCM.By improving the sealing design and reducing the machine tolerance of the source,the minimum power consumption reduces from 9 SCCM to 4 SCCM,thus having better energy efficiency and benefiting for the pumping system.Preliminary DC extractions show that H–microampere current ranges from several tens to hundreds under different operation conditions.Some problems during the experiments and future plan are discussed in the end. 展开更多
关键词 离子源 冷阴极 回旋加速器 G型 密封设计 实验过程 物理研究所 放电特性
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