Flavonoid-based nanomaterials have extensive potential in antimicrobial research because of their non-toxicity,large-scale producibility,and chemical stability.An efficient combination of flavonoids and rare earth met...Flavonoid-based nanomaterials have extensive potential in antimicrobial research because of their non-toxicity,large-scale producibility,and chemical stability.An efficient combination of flavonoids and rare earth metals can have excellent antimicrobial properties owing to their robust medicinal and physicochemical properties.In this study,we synthesized copper oxide(CuO)nanoparticles(NPs)using a reflux reaction and repeated doping with the rare earth element lanthanum to prepare La-CuO NPs.Next,these La-CuO NPs were functionalized with the flavonoid curcumin,and the modified NPs were termed Cu-La-CuO NPs.These NPs were chemically characterized via microscopic and spectroscopic techniques,including transmission electron microscopy(TEM),scanning electron microscopy(SEM),ultraviolet-visible(UV-Vis)adsorption,Fourier transform infrared spectroscopy(FT-IR)spectroscopy,and powder X-ray diffraction(XRD)analysis.The SEM-EDX analysis reveals the elements doped into the native CuO NPs.The TEM and XRD characterization results show,in detail,the distinct morphology and phase composition of the prepared CuO,La-CuO,and Cu-La-CuO NPs.The antimicrobial activity of the Cu-La-CuO NPs was investigated on bacteria,such as Escherichia coli(E.coli)and Bacillus subtilis(B.subtilis),and fungi,including Aspergillus niger(A niger).The Cu-La-CuO NPs delivers excellent antimicrobial effects due to the incorporation of lanthanum and curcumin into the CuO NPs.The Cu-La-CuO NPs show excellent antimicrobial potentials with an adequate zone of inhibition values around 2.2 and 2.9 mm in E.coli and A.niger,respectively.Live and dead analysis studies suggest the antimicrobial effects of lanthanum and curcumin moieties over native CuO NPs.The obtained results are significant in developing of rare earth metal-based flavo no id-conjugated nanocomposites against typical microbes.展开更多
Copper oxide nanoparticles(CuO NPs)were synthesised with laser ablation of a copper sheet immersed in deionized water(DW),cetrimonium bromide(CTAB),and sodium dodecyl sulphate(SDS),respectively.The target was irradiat...Copper oxide nanoparticles(CuO NPs)were synthesised with laser ablation of a copper sheet immersed in deionized water(DW),cetrimonium bromide(CTAB),and sodium dodecyl sulphate(SDS),respectively.The target was irradiated with a pulsed Nd:YAG laser at 1064 nm,600 mJ,a pulse duration of 10 ns,and a repetition rate of 5 Hz.The CuO NPs colloidal were analyzed using UV–Vis spectroscopy,the Fourier transform infrared(FTIR)spectrometer,zeta potential(ZP),X-ray diffraction(XRD),transmission electron microscope(TEM)and field emission scanning electron microscopy(FESEM).The absorption spectra of CuO NPs colloidal showed peaks at 214,215 and 220 nm and low-intensity peaks at 645,650 and 680 nm for SDS,CTAB and DW,respectively.CuO NPs’colloidal results are(−21.6,1.2,and 80 mV)for negatively,neutrally,and positively charged SDS,DW,and CTAB,respectively.The XRD pattern of the NPs revealed the presence of CuO phase planes(110)(111),(20-2)and(11-1).The TEM images revealed nearly spherical NPs,with sizes ranging from 10–90,10–50,and 10–210 nm for CuO NPs mixed with DW,SDS and CTAB,respectively.FESEM images of all the synthesized samples illustrate the formation of spherical nanostructure and large particles are observable.The CuO NPs were tested for antibacterial activity against Streptococcus mutans by using the well diffusion method.In this method,CuO NPs prepared in DW at a concentration of 200μg/mL showed a greater inhibition zone against Streptococcus mutans.展开更多
The enhancement of the physicochemical characteristics of fossil fuel has been the subject of extensive research to achieve better efficiency and reduced emissions. Diesel is one of the fossil fuels that are highly co...The enhancement of the physicochemical characteristics of fossil fuel has been the subject of extensive research to achieve better efficiency and reduced emissions. Diesel is one of the fossil fuels that are highly consumed in daily life. This paper focuses on the behavior of a refined diesel fuel when copper oxide nanoparticles are added. The resulting blend ofnano-diesel has been analyzed using a four-stroke engine under two loads indicating light vehicles and heavy duty vehicles. The nano-diesel was prepared by the aid of an ultrasonicator and a mechanical homogenizer. A base diesel was taken as a reference to distinguish the effect of the nanoparticles additives. Three different samples with different concentrations are utilized in this study. As a result, the fuel consumption, exhaust temperature, brake power, power losses and engine efficiency have been evaluated and compared to the base diesel in order to demonstrate and access the enhanced performance of the nano-fuel blend. The three concentrations conducted were 100 ppm, 200 ppm and 300 ppm of copper oxide nanoparticles. The results represented that the pure refinery diesel has low exhaust temperatures, high brake power and high efficiency as compared to the commercial diesel supplied from a gas station. In addition, 300 ppm copper oxide nano-diesel showed improvement in engine performances as compared to the other concentrations and pure diesel. In this context, lowest fuel consumption for both passenger cars and heavy duty vehicles was achieved, brake power for passenger cars only was improved and input power showed improvement however, exhaust temperature was the highest as for this fuel.展开更多
The antibacterial activity of various nanoparticles is gaining increasing interest due to its potential medical applications.In this work,we presented the synthesis of copper oxide nanoparticles prepared by chemical r...The antibacterial activity of various nanoparticles is gaining increasing interest due to its potential medical applications.In this work,we presented the synthesis of copper oxide nanoparticles prepared by chemical reduction from aqueous solutions of copper sulfate(CuSO_(4))with sodium borohydride(NaBH_(4))and hydrazine hydrate(N_(2)H_(4))as reductant and polyvinylpyrrolidone(PVP)as stabilizer.The X-ray diffraction spectra showed the formation of tenorite(CuO)and cuprite(Cu_(2)O)nanoparticles when different ratios of CuSO_(4)/NaBH_(4) and CuSO_(4)/N_(2)H_(4) were used.Photographs obtained by transmission electron microscopy(TEM)showed agglomerates of grains with a narrow size distribution(from 20 to 70 nm),whereas the radii of the individual particles were between 2 and 20 nm.Smaller nanoparticles and narrower particle size distributions were obtained when NaBH_(4) was used.The results of antibacterial activity using the Kirby-Bauer method showed that nanoparticles obtained with NaBH_(4) presented a reasonable bactericidal activity.Pseudomonas aureginosa and Staphylococcus aureus were more susceptible to the particle size than Escherichia coli.In addition,with small amounts of Cu_(2)O in samples of CuO nanoparticles,the antibacterial susceptibility against Pseudomonas aureginosa was improved.Finally,nanoparticles of CuO incorporated into cotton by applying ultrasound waves remained impregnated after five washes.展开更多
Nanoparticles(NPs)are widely used for their special physical properties and released into the natural environment.When two types of NPs exist in the same environment,the presence of one type of NP may affect the prope...Nanoparticles(NPs)are widely used for their special physical properties and released into the natural environment.When two types of NPs exist in the same environment,the presence of one type of NP may affect the properties of the other type of NP.This study investigated the toxic effects of multi-walled carbon nanotubes(MWCNTs)and copper oxide nanoparticles(Cu O NPs)on Tetradesmus obliquus.Both NPs had toxic effects on algae,and the toxic effects of MWCNTs were significantly stronger than Cu O NPs which the 96-hr median effective concentration to algae were 33.8 and 169.2 mg/L,respectively.Oxidative stress and cell membrane damage were the main reasons for the toxicity of NPs to algae,and they were concentration-dependent,and the existence of Cu O NPs in some groups reduced cell membrane damage caused by MWCNTs which may because that Cu O NPs formed heteroaggregation with MWCNTs,reducing the contact of nanoparticles with cell membranes,then reducing physical damage.Scanning electron microscopy(SEM)and transmission electron microscope(TEM)results indicated cell damage,the heteroaggregation of MWCNTs-Cu O NPs and obvious nanoparticles internalization.In some groups,the presence of Cu O NPs significantly reduced reactive oxygen species(ROS)level induced by MWCNTs.However,for the highest concentration group,the ROS level was much higher than that of the two NPs alone treatment groups,which might be related to the high concentration of MWCNTs promoting the internalization of Cu O NPs.MWCNTs and Cu O NPs affected and interacted with each other,causing more complex toxic effects on aquatic organisms.展开更多
Nanomedicine has tremendous prospects for the improvement of the diagnosis and treatment of human diseases. Nanotechnology has the potential to revolutionize a wide array of tools in biotechnology so that they are mor...Nanomedicine has tremendous prospects for the improvement of the diagnosis and treatment of human diseases. Nanotechnology has the potential to revolutionize a wide array of tools in biotechnology so that they are more personalized, portable, cheaper, safer and easier to administer. The present study aims to study the impact of copper oxide and selenium nanoparticles on the oxidative stress in sera of myocardial infraction patients through the synthesis and characterization of copper oxide and selenium nanoparticles, and the evaluation of the status of oxidative stress in sera of myocardial infraction patients through measurement of the activities of myeloperoxidase and gamma-glutamyl transferase in the presence and absence of nanoparticles in sera of myocardial infraction patients. Cupric oxide nanoparticles and selenium nanoparticles have been prepared by a chemical method and by laser ablation method respectively, and have been characterized. The result indicated that copper oxide (grain shapes with the average size 30 - 80 nm) and selenium nanoparticles (rod-shaped structures with the average size 70 - 90 nm) had an inhibition effects on myeloperoxidase and gamma-glutamyl transferase activities, and as a result had an inhibition effects on oxidative stress.展开更多
Copper oxide nanowires and nanoparticles were fabricated through electrospinning followed by calcinations in different heating conditions.It was found that the solution viscosity and environment humidity had great imp...Copper oxide nanowires and nanoparticles were fabricated through electrospinning followed by calcinations in different heating conditions.It was found that the solution viscosity and environment humidity had great impact on the morphologies of precursor nanowires,and the parameters of heat treatment,including final temperature and heating rate,significantly affected the product morphologies.展开更多
It is common knowledge that phase-change materials are used for the purpose of thermal storage because of the characteristics that are exclusive to these materials and not found in others.These characteristics include...It is common knowledge that phase-change materials are used for the purpose of thermal storage because of the characteristics that are exclusive to these materials and not found in others.These characteristics include a large capacity for absorbing heat and a large capacity for releasing heat when the phase changes;however,these materials have a low thermal conductivity.This paper presents the results of an experimental study that investigated the impact that nanoparticles of copper oxide had on reducing the temperature of solar panels.The phase change substance that was used was determined to be beeswax.The impact of adding nanoscale copper oxide at a concentration of 0.05%of the total mass of wax was investigated and compared to a reference solar panel that did not contain any nanoscale additions.The findings demonstrated that the incorporation of nanoscale copper oxide brought about a reduction of three℃ in the plate’s average temperature as well as a one percent improvement in its electrical efficiency.In cases where it seems that the use of nanoparticles might potentially enhance the performance of integrated solar energy systems that contain phase change.展开更多
In the present study,copper oxide(CuO)nanoparticles were biosynthesized from an Aspergillus niger cell-free extract(CFE),and several optimal operating parameters that affected the formation and dimensions of the CuO n...In the present study,copper oxide(CuO)nanoparticles were biosynthesized from an Aspergillus niger cell-free extract(CFE),and several optimal operating parameters that affected the formation and dimensions of the CuO nanoparticles were determined,as follows:15 mmol/L metal salt and 90 mL of CFE at room temperature for 24 h,to achieve an average size of 77 nm.Spectroscopic studies revealed an association between alcohol,alkene,and amine functional groups and the grain-shaped CuO nanoparticles.The elemental composition of the nanoparticles was confirmed by energy dispersive X-ray spectroscopy(EDX)data.Mycogenic CuO nanoparticles exhibited excellent antibacterial activity against Gram-positive bacterial species compared with Gram-negative bacterial species,i.e.,Streptococcus pneumoniae MTCC 2672,Staphylococcus aureus MTCC 737,Micrococcus luteus MTCC 11948,Pseudomonas aeruginosa MTCC 424,and Escherichia coli MTCC 443,at 200 mg/mL,with inhibition zones of 9.2,8.37.7,7.2,and 6.1 mm,respectively.Finally,myogenic CuO nanoparticles exhibited good antifungal activity against Aspergillus fumigatus and Aspergillus versicolor.展开更多
基金the Gachon University Research Fund of 2021(GCU-2021-10360001)。
文摘Flavonoid-based nanomaterials have extensive potential in antimicrobial research because of their non-toxicity,large-scale producibility,and chemical stability.An efficient combination of flavonoids and rare earth metals can have excellent antimicrobial properties owing to their robust medicinal and physicochemical properties.In this study,we synthesized copper oxide(CuO)nanoparticles(NPs)using a reflux reaction and repeated doping with the rare earth element lanthanum to prepare La-CuO NPs.Next,these La-CuO NPs were functionalized with the flavonoid curcumin,and the modified NPs were termed Cu-La-CuO NPs.These NPs were chemically characterized via microscopic and spectroscopic techniques,including transmission electron microscopy(TEM),scanning electron microscopy(SEM),ultraviolet-visible(UV-Vis)adsorption,Fourier transform infrared spectroscopy(FT-IR)spectroscopy,and powder X-ray diffraction(XRD)analysis.The SEM-EDX analysis reveals the elements doped into the native CuO NPs.The TEM and XRD characterization results show,in detail,the distinct morphology and phase composition of the prepared CuO,La-CuO,and Cu-La-CuO NPs.The antimicrobial activity of the Cu-La-CuO NPs was investigated on bacteria,such as Escherichia coli(E.coli)and Bacillus subtilis(B.subtilis),and fungi,including Aspergillus niger(A niger).The Cu-La-CuO NPs delivers excellent antimicrobial effects due to the incorporation of lanthanum and curcumin into the CuO NPs.The Cu-La-CuO NPs show excellent antimicrobial potentials with an adequate zone of inhibition values around 2.2 and 2.9 mm in E.coli and A.niger,respectively.Live and dead analysis studies suggest the antimicrobial effects of lanthanum and curcumin moieties over native CuO NPs.The obtained results are significant in developing of rare earth metal-based flavo no id-conjugated nanocomposites against typical microbes.
文摘Copper oxide nanoparticles(CuO NPs)were synthesised with laser ablation of a copper sheet immersed in deionized water(DW),cetrimonium bromide(CTAB),and sodium dodecyl sulphate(SDS),respectively.The target was irradiated with a pulsed Nd:YAG laser at 1064 nm,600 mJ,a pulse duration of 10 ns,and a repetition rate of 5 Hz.The CuO NPs colloidal were analyzed using UV–Vis spectroscopy,the Fourier transform infrared(FTIR)spectrometer,zeta potential(ZP),X-ray diffraction(XRD),transmission electron microscope(TEM)and field emission scanning electron microscopy(FESEM).The absorption spectra of CuO NPs colloidal showed peaks at 214,215 and 220 nm and low-intensity peaks at 645,650 and 680 nm for SDS,CTAB and DW,respectively.CuO NPs’colloidal results are(−21.6,1.2,and 80 mV)for negatively,neutrally,and positively charged SDS,DW,and CTAB,respectively.The XRD pattern of the NPs revealed the presence of CuO phase planes(110)(111),(20-2)and(11-1).The TEM images revealed nearly spherical NPs,with sizes ranging from 10–90,10–50,and 10–210 nm for CuO NPs mixed with DW,SDS and CTAB,respectively.FESEM images of all the synthesized samples illustrate the formation of spherical nanostructure and large particles are observable.The CuO NPs were tested for antibacterial activity against Streptococcus mutans by using the well diffusion method.In this method,CuO NPs prepared in DW at a concentration of 200μg/mL showed a greater inhibition zone against Streptococcus mutans.
文摘The enhancement of the physicochemical characteristics of fossil fuel has been the subject of extensive research to achieve better efficiency and reduced emissions. Diesel is one of the fossil fuels that are highly consumed in daily life. This paper focuses on the behavior of a refined diesel fuel when copper oxide nanoparticles are added. The resulting blend ofnano-diesel has been analyzed using a four-stroke engine under two loads indicating light vehicles and heavy duty vehicles. The nano-diesel was prepared by the aid of an ultrasonicator and a mechanical homogenizer. A base diesel was taken as a reference to distinguish the effect of the nanoparticles additives. Three different samples with different concentrations are utilized in this study. As a result, the fuel consumption, exhaust temperature, brake power, power losses and engine efficiency have been evaluated and compared to the base diesel in order to demonstrate and access the enhanced performance of the nano-fuel blend. The three concentrations conducted were 100 ppm, 200 ppm and 300 ppm of copper oxide nanoparticles. The results represented that the pure refinery diesel has low exhaust temperatures, high brake power and high efficiency as compared to the commercial diesel supplied from a gas station. In addition, 300 ppm copper oxide nano-diesel showed improvement in engine performances as compared to the other concentrations and pure diesel. In this context, lowest fuel consumption for both passenger cars and heavy duty vehicles was achieved, brake power for passenger cars only was improved and input power showed improvement however, exhaust temperature was the highest as for this fuel.
基金supported by the Pontifical Catholic University of Peru(20120098).
文摘The antibacterial activity of various nanoparticles is gaining increasing interest due to its potential medical applications.In this work,we presented the synthesis of copper oxide nanoparticles prepared by chemical reduction from aqueous solutions of copper sulfate(CuSO_(4))with sodium borohydride(NaBH_(4))and hydrazine hydrate(N_(2)H_(4))as reductant and polyvinylpyrrolidone(PVP)as stabilizer.The X-ray diffraction spectra showed the formation of tenorite(CuO)and cuprite(Cu_(2)O)nanoparticles when different ratios of CuSO_(4)/NaBH_(4) and CuSO_(4)/N_(2)H_(4) were used.Photographs obtained by transmission electron microscopy(TEM)showed agglomerates of grains with a narrow size distribution(from 20 to 70 nm),whereas the radii of the individual particles were between 2 and 20 nm.Smaller nanoparticles and narrower particle size distributions were obtained when NaBH_(4) was used.The results of antibacterial activity using the Kirby-Bauer method showed that nanoparticles obtained with NaBH_(4) presented a reasonable bactericidal activity.Pseudomonas aureginosa and Staphylococcus aureus were more susceptible to the particle size than Escherichia coli.In addition,with small amounts of Cu_(2)O in samples of CuO nanoparticles,the antibacterial susceptibility against Pseudomonas aureginosa was improved.Finally,nanoparticles of CuO incorporated into cotton by applying ultrasound waves remained impregnated after five washes.
基金supported by the National Natural Science Foundation of China(Nos.51521006,51579095,51378190)Ecology and Environment Department of Hunan,the Program for Changjiang Scholars and Innovative Research Team in University(No.IRT-13R17)。
文摘Nanoparticles(NPs)are widely used for their special physical properties and released into the natural environment.When two types of NPs exist in the same environment,the presence of one type of NP may affect the properties of the other type of NP.This study investigated the toxic effects of multi-walled carbon nanotubes(MWCNTs)and copper oxide nanoparticles(Cu O NPs)on Tetradesmus obliquus.Both NPs had toxic effects on algae,and the toxic effects of MWCNTs were significantly stronger than Cu O NPs which the 96-hr median effective concentration to algae were 33.8 and 169.2 mg/L,respectively.Oxidative stress and cell membrane damage were the main reasons for the toxicity of NPs to algae,and they were concentration-dependent,and the existence of Cu O NPs in some groups reduced cell membrane damage caused by MWCNTs which may because that Cu O NPs formed heteroaggregation with MWCNTs,reducing the contact of nanoparticles with cell membranes,then reducing physical damage.Scanning electron microscopy(SEM)and transmission electron microscope(TEM)results indicated cell damage,the heteroaggregation of MWCNTs-Cu O NPs and obvious nanoparticles internalization.In some groups,the presence of Cu O NPs significantly reduced reactive oxygen species(ROS)level induced by MWCNTs.However,for the highest concentration group,the ROS level was much higher than that of the two NPs alone treatment groups,which might be related to the high concentration of MWCNTs promoting the internalization of Cu O NPs.MWCNTs and Cu O NPs affected and interacted with each other,causing more complex toxic effects on aquatic organisms.
文摘Nanomedicine has tremendous prospects for the improvement of the diagnosis and treatment of human diseases. Nanotechnology has the potential to revolutionize a wide array of tools in biotechnology so that they are more personalized, portable, cheaper, safer and easier to administer. The present study aims to study the impact of copper oxide and selenium nanoparticles on the oxidative stress in sera of myocardial infraction patients through the synthesis and characterization of copper oxide and selenium nanoparticles, and the evaluation of the status of oxidative stress in sera of myocardial infraction patients through measurement of the activities of myeloperoxidase and gamma-glutamyl transferase in the presence and absence of nanoparticles in sera of myocardial infraction patients. Cupric oxide nanoparticles and selenium nanoparticles have been prepared by a chemical method and by laser ablation method respectively, and have been characterized. The result indicated that copper oxide (grain shapes with the average size 30 - 80 nm) and selenium nanoparticles (rod-shaped structures with the average size 70 - 90 nm) had an inhibition effects on myeloperoxidase and gamma-glutamyl transferase activities, and as a result had an inhibition effects on oxidative stress.
基金The National Natural Science Foundation of China(Grant No.51171006)The Key Research Project in Science and Technology of Leshan(Grant No.12GZD066)
文摘Copper oxide nanowires and nanoparticles were fabricated through electrospinning followed by calcinations in different heating conditions.It was found that the solution viscosity and environment humidity had great impact on the morphologies of precursor nanowires,and the parameters of heat treatment,including final temperature and heating rate,significantly affected the product morphologies.
文摘It is common knowledge that phase-change materials are used for the purpose of thermal storage because of the characteristics that are exclusive to these materials and not found in others.These characteristics include a large capacity for absorbing heat and a large capacity for releasing heat when the phase changes;however,these materials have a low thermal conductivity.This paper presents the results of an experimental study that investigated the impact that nanoparticles of copper oxide had on reducing the temperature of solar panels.The phase change substance that was used was determined to be beeswax.The impact of adding nanoscale copper oxide at a concentration of 0.05%of the total mass of wax was investigated and compared to a reference solar panel that did not contain any nanoscale additions.The findings demonstrated that the incorporation of nanoscale copper oxide brought about a reduction of three℃ in the plate’s average temperature as well as a one percent improvement in its electrical efficiency.In cases where it seems that the use of nanoparticles might potentially enhance the performance of integrated solar energy systems that contain phase change.
文摘In the present study,copper oxide(CuO)nanoparticles were biosynthesized from an Aspergillus niger cell-free extract(CFE),and several optimal operating parameters that affected the formation and dimensions of the CuO nanoparticles were determined,as follows:15 mmol/L metal salt and 90 mL of CFE at room temperature for 24 h,to achieve an average size of 77 nm.Spectroscopic studies revealed an association between alcohol,alkene,and amine functional groups and the grain-shaped CuO nanoparticles.The elemental composition of the nanoparticles was confirmed by energy dispersive X-ray spectroscopy(EDX)data.Mycogenic CuO nanoparticles exhibited excellent antibacterial activity against Gram-positive bacterial species compared with Gram-negative bacterial species,i.e.,Streptococcus pneumoniae MTCC 2672,Staphylococcus aureus MTCC 737,Micrococcus luteus MTCC 11948,Pseudomonas aeruginosa MTCC 424,and Escherichia coli MTCC 443,at 200 mg/mL,with inhibition zones of 9.2,8.37.7,7.2,and 6.1 mm,respectively.Finally,myogenic CuO nanoparticles exhibited good antifungal activity against Aspergillus fumigatus and Aspergillus versicolor.
