The ability to generate high pressures in a large-volume press(LVP)is crucial for the study of matter under extreme conditions.Here,we have achieved ultrahigh pressures of and 50 GPa,respectively,at room temperature a...The ability to generate high pressures in a large-volume press(LVP)is crucial for the study of matter under extreme conditions.Here,we have achieved ultrahigh pressures of and 50 GPa,respectively,at room temperature and a high temperature of 1900 K∼60within a millimeter-sized sample volume in a Kawai-type LVP(KLVP)using hard tungsten carbide(WC)and newly designed assem-blies.The introduction of electroconductive polycrystalline boron-doped diamond and dense alumina wrapped with Cu foils into a large conventional cell assembly enables the detection of resistance variations in the Fe_(2)O_(3) pressure standard upon compression.The efficiency of pressure generation in the newly developed cell assembly equipped with conventional ZK10F WC anvils is significantly higher than that of conventional assemblies with some ultrahard or tapered WC anvils.Our study has enabled the routine gener-ation of pressures exceeding 50 GPa within a millimeter-sized sample chamber that have been inaccessible with traditional KLVPs.This advance in high-pressure technology not only breaks a record for pressure generation in traditional KLVPs,but also opens up new avenues for exploration of the properties of the Earth’s deep interior and for the synthesis of novel materials at extreme high pressures.展开更多
Objective: to study and analyze the specific value of sodium hyaluronate combined with joint manipulative release on analgesia in patients with scapulohumeral periarthritis. Methods: in our hospital from December 2018...Objective: to study and analyze the specific value of sodium hyaluronate combined with joint manipulative release on analgesia in patients with scapulohumeral periarthritis. Methods: in our hospital from December 2018 to December 2019, with the consent of the medical ethics committee of our hospital, 60 patients with scapulohumeral periarthritis were collected and each patient was ranked according to the time of admission. The odd number of 30 patients was in the study group, which was treated with sodium hyaluronate combined with joint manipulative release. And the even number of 30 patients was in the reference group, which was injected subacromial articular cavity with sodium hyaluronate combined with conventional treatment. Study and analyze the pain feeling of patients in the process of treatment. Results: after the intervention, the pain of the study group was lower than that of the reference group, and the difference between the two groups was statistically significant (P < 0.05). Conclusion: sodium hyaluronate combined with joint manipulative release has a positive effect on analgesia in patients with scapulohumeral periarthritis, which is worthy of clinical application.展开更多
基金supported by the National Key R&D Program of China(Grant No.2023YFA1406200)the National Natural Science Foundation of China(Grant Nos.42272041 and 52302043)+2 种基金the National Natural Science Foundation of China(Grant No.U23A20561)the Jilin University High-level Innovation Team Foundation(Grant No.2021TD–05)the Shanghai Synchrotron Radiation Facility(Grant Nos.2024-SSRF-PT-510031 and 505511).
文摘The ability to generate high pressures in a large-volume press(LVP)is crucial for the study of matter under extreme conditions.Here,we have achieved ultrahigh pressures of and 50 GPa,respectively,at room temperature and a high temperature of 1900 K∼60within a millimeter-sized sample volume in a Kawai-type LVP(KLVP)using hard tungsten carbide(WC)and newly designed assem-blies.The introduction of electroconductive polycrystalline boron-doped diamond and dense alumina wrapped with Cu foils into a large conventional cell assembly enables the detection of resistance variations in the Fe_(2)O_(3) pressure standard upon compression.The efficiency of pressure generation in the newly developed cell assembly equipped with conventional ZK10F WC anvils is significantly higher than that of conventional assemblies with some ultrahard or tapered WC anvils.Our study has enabled the routine gener-ation of pressures exceeding 50 GPa within a millimeter-sized sample chamber that have been inaccessible with traditional KLVPs.This advance in high-pressure technology not only breaks a record for pressure generation in traditional KLVPs,but also opens up new avenues for exploration of the properties of the Earth’s deep interior and for the synthesis of novel materials at extreme high pressures.
文摘Objective: to study and analyze the specific value of sodium hyaluronate combined with joint manipulative release on analgesia in patients with scapulohumeral periarthritis. Methods: in our hospital from December 2018 to December 2019, with the consent of the medical ethics committee of our hospital, 60 patients with scapulohumeral periarthritis were collected and each patient was ranked according to the time of admission. The odd number of 30 patients was in the study group, which was treated with sodium hyaluronate combined with joint manipulative release. And the even number of 30 patients was in the reference group, which was injected subacromial articular cavity with sodium hyaluronate combined with conventional treatment. Study and analyze the pain feeling of patients in the process of treatment. Results: after the intervention, the pain of the study group was lower than that of the reference group, and the difference between the two groups was statistically significant (P < 0.05). Conclusion: sodium hyaluronate combined with joint manipulative release has a positive effect on analgesia in patients with scapulohumeral periarthritis, which is worthy of clinical application.
