A new approach was proposed to describe settlement behavior of an unsaturated soil with subgrade filling for high-speed railway. Firstly, based on Terzaghi consolidation theory, equations considering the variation coe...A new approach was proposed to describe settlement behavior of an unsaturated soil with subgrade filling for high-speed railway. Firstly, based on Terzaghi consolidation theory, equations considering the variation coefficient of consolidation with void ratio and saturation for consolidation of an unsaturated soil under stage continuous loading were derived, and according to analytical solutions of equations, a formula for settlement computation under stage continuous loading was obtained. Then, combined with the width-to-height ratio of subgrade to compute ground reaction, and by means of in-situ plate loading curves, a correctional approach was presented for the analysis of nonlinear settlement of foundation. Also, the comparison between calculated and measured loadsettlement behavior for an unsaturated soil in Qingdao-Ji'nan high-speed railway was given to demonstrate the effectiveness and accuracy of the proposed approach. It can be noted that the presented solution can be used to predict the settlement of an unsaturated soil foundation under stage continuous loading in engineering design.展开更多
In verifying antiretroviral efficacy of a Nigerian broad spectrum antiviral medicine (Antivirt<span style="white-space:nowrap;"><sup>®</sup></span>), the Nigerian Institute o...In verifying antiretroviral efficacy of a Nigerian broad spectrum antiviral medicine (Antivirt<span style="white-space:nowrap;"><sup>®</sup></span>), the Nigerian Institute of Medical Research certified it safe by toxicological test on laboratory animals, before commencing treatment of three HIV/AIDS patients whose viral loads varied widely (millions, hundreds of thousands and thousands). To overcome errors associated with such wide differences in subject-classes, percentages of viral load-reductions were calculated instead of comparing their viral loads. After first month of the Antivirt<span style="white-space:nowrap;"><sup>®</sup></span>-treatment, means of ranked viral loads of the patients significantly (P ≤ 0.05) increased from 10.00 ± 7.21 to 11.30 ± 5.51 (-41.03% infection-reduction rate) instead of reducing. From second month of the trial, their viral loads started to reduce, continuously, so that their infection-reduction rates have been increasing from that -41.03%, to -38.22% in the second month;23.98% in the third month;31.76% in the fourth month and 64.12% after the fifth month.展开更多
基金Project(2010G003-F)supported by the Research and Development Program for Technology of the Chinese Ministry of Railway
文摘A new approach was proposed to describe settlement behavior of an unsaturated soil with subgrade filling for high-speed railway. Firstly, based on Terzaghi consolidation theory, equations considering the variation coefficient of consolidation with void ratio and saturation for consolidation of an unsaturated soil under stage continuous loading were derived, and according to analytical solutions of equations, a formula for settlement computation under stage continuous loading was obtained. Then, combined with the width-to-height ratio of subgrade to compute ground reaction, and by means of in-situ plate loading curves, a correctional approach was presented for the analysis of nonlinear settlement of foundation. Also, the comparison between calculated and measured loadsettlement behavior for an unsaturated soil in Qingdao-Ji'nan high-speed railway was given to demonstrate the effectiveness and accuracy of the proposed approach. It can be noted that the presented solution can be used to predict the settlement of an unsaturated soil foundation under stage continuous loading in engineering design.
文摘In verifying antiretroviral efficacy of a Nigerian broad spectrum antiviral medicine (Antivirt<span style="white-space:nowrap;"><sup>®</sup></span>), the Nigerian Institute of Medical Research certified it safe by toxicological test on laboratory animals, before commencing treatment of three HIV/AIDS patients whose viral loads varied widely (millions, hundreds of thousands and thousands). To overcome errors associated with such wide differences in subject-classes, percentages of viral load-reductions were calculated instead of comparing their viral loads. After first month of the Antivirt<span style="white-space:nowrap;"><sup>®</sup></span>-treatment, means of ranked viral loads of the patients significantly (P ≤ 0.05) increased from 10.00 ± 7.21 to 11.30 ± 5.51 (-41.03% infection-reduction rate) instead of reducing. From second month of the trial, their viral loads started to reduce, continuously, so that their infection-reduction rates have been increasing from that -41.03%, to -38.22% in the second month;23.98% in the third month;31.76% in the fourth month and 64.12% after the fifth month.
