Anhedonia, the lowered ability to experience pleasure, is one of the non-motor symptoms in Parkinson’s disease. Recently, the distinction between consummatory and anticipatory anhedonia has been proposed and anhedoni...Anhedonia, the lowered ability to experience pleasure, is one of the non-motor symptoms in Parkinson’s disease. Recently, the distinction between consummatory and anticipatory anhedonia has been proposed and anhedonia, notably in PD, could constitute a stable characteristic (anhedonia-trait) or secondary symptom (anhedonia-state). Several studies, using healthy control groups, reported high state consummatory and anticipatory anhedonia in PD using the Snaith Hamilton Pleasure Scale (SHAPS), but when control groups included subjects with different illnesses no significant differences were reported. The aim of the present study was to compare PD subjects with subjects presenting a non-Parkinson motor neurological disease on the anhedonia subscale of the Beck Depression Inventory (BDI-II). This subscale rated consummatory and anticipatory anhedonia state. No significant difference was reported. This result confirmed that PD subjects were not characterized by high levels of state anhedonia when the subjects were compared to subjects with a different disease. Contrary to trait consummatory anhedonia, state anhedonia could be nonspecific to Parkinson’s disease.展开更多
During social interactions,animals must decide not only what actions to take toward conspecifics,such as fighting or mating,but also when to initiate consummatory behaviours.This ability is crucial for gregarious anim...During social interactions,animals must decide not only what actions to take toward conspecifics,such as fighting or mating,but also when to initiate consummatory behaviours.This ability is crucial for gregarious animals,including humans.展开更多
文摘Anhedonia, the lowered ability to experience pleasure, is one of the non-motor symptoms in Parkinson’s disease. Recently, the distinction between consummatory and anticipatory anhedonia has been proposed and anhedonia, notably in PD, could constitute a stable characteristic (anhedonia-trait) or secondary symptom (anhedonia-state). Several studies, using healthy control groups, reported high state consummatory and anticipatory anhedonia in PD using the Snaith Hamilton Pleasure Scale (SHAPS), but when control groups included subjects with different illnesses no significant differences were reported. The aim of the present study was to compare PD subjects with subjects presenting a non-Parkinson motor neurological disease on the anhedonia subscale of the Beck Depression Inventory (BDI-II). This subscale rated consummatory and anticipatory anhedonia state. No significant difference was reported. This result confirmed that PD subjects were not characterized by high levels of state anhedonia when the subjects were compared to subjects with a different disease. Contrary to trait consummatory anhedonia, state anhedonia could be nonspecific to Parkinson’s disease.
基金National Natural Science Foundation of China(32125018)National Key Research and Development Program of China(2021YFA1101701)+5 种基金Zhejiang Provincial Natural Science Foundation of China(LD24H090002)Nanhu Brain-computer Interface Institute(010904008)Fundamental Research Funds for the Central Universities(226-2024-00133)Key R&D Program of Zhejiang(2024SSYS0016)Non-profit Central Research Institute Fund of the Chinese Academy of Medical Sciences(2023-PT310-01)MOE Frontiers Science Center for Brain Science&Brain-Machine Integration of Zhejiang University。
文摘During social interactions,animals must decide not only what actions to take toward conspecifics,such as fighting or mating,but also when to initiate consummatory behaviours.This ability is crucial for gregarious animals,including humans.
