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Exploring the Associations between Sedentary Time,Social Support,Social Rejection and Psychological Distress:A Network Analysis in Students
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作者 Yuyang Nie Kunkun Jiang +5 位作者 Tianci Wang Cong Liu Kangli Du Yuxian Cao Guofeng Qu Lijia Hou 《International Journal of Mental Health Promotion》 2026年第1期47-59,共13页
Background:Amid the global rise in adolescent sedentary behavior and psychological distress,extant research has largely focused on variable-level associations,neglecting symptom-level interactions.This study applies n... Background:Amid the global rise in adolescent sedentary behavior and psychological distress,extant research has largely focused on variable-level associations,neglecting symptom-level interactions.This study applies network analysis,aims to delineate the interconnections among sedentary time,social support,social exclusion,and psychological distress in Chinese students,and to identify core and bridge symptoms to inform targeted interventions.Methods:This study employed a cross-sectional design to investigate the complex relationships among sedentary behavior,social support,social exclusion,and psychological distress among Chinese students.The research involved 459 high school and university students,using network analysis and mediation models to examine these relationships.Results:Network analysis revealed that the network had a density of 58.33%and an average edge weight of 0.11.In terms of centrality,stress had the highest expected influence(EI=1.135),acting as the core amplifier in the network.Sedentary behavior demonstrated the highest bridging expected influence,functioning as a critical bridge for cross-community transmission.Conversely,friend support showed the lowest bridging EI with a negative value,indicating its effectiveness in blocking cross-community diffusion and alleviating symptoms.Conclusion:With stress acting as the most influential“core engine”within the symptom network and sedentary behavior serving as the key“bridge”for cross-community transmission,interventions should first target stress to weaken the overall symptom cascade,followed by reducing sedentary behavior or enhancing friend support to disrupt cross-community pathways,thereby achieving a core-bridge dual blockade. 展开更多
关键词 Sedentary behavior psychological distress social support social exclusion network analysis
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Topological analysis of the depression-anxiety-stress network in vocational college freshmen:A longitudinal trace-based analysis
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作者 Siliang Yang Mengying Xu 《Journal of Psychology in Africa》 2026年第1期21-32,共12页
This study explores the core characteristics,dynamic progression of the depression-anxiety-stress network among Chinese higher vocational college freshmen and its association with life satisfaction,and identifies key ... This study explores the core characteristics,dynamic progression of the depression-anxiety-stress network among Chinese higher vocational college freshmen and its association with life satisfaction,and identifies key nodes and critical intervention points.Participants were 295 higher vocational college freshmen(male=137;M=18.52,SD=0.69)completing two follow-up surveys(5-month interval).Measures included depression-anxiety-stress symptoms and life satisfaction,analyzed via cross-sectional and binary cross-lagged panel network analysis.The results showed that“Easily agitated”was the central node(strength=1.519,EI=1.967);“Irritable”and“Mouth Dryness”were top predictors(Out-EI=1.101,1.100),with depressive symptoms as the convergence hub.“Easily agitated”had the strongest direct negative impact on life satisfaction(cross-cluster out-predictability=−0.653).This study elucidates depression-anxietystress network mechanisms in higher vocational freshmen,providing a theoretical framework and targeted intervention guidance(e.g.,focusing on somatic and emotional nodes). 展开更多
关键词 Vocational college freshmen depression-anxiety-stress network topology longitudinal analysis life satisfaction
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Combined Fault Tree Analysis and Bayesian Network for Reliability Assessment of Marine Internal Combustion Engine
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作者 Ivana Jovanović Çağlar Karatuğ +1 位作者 Maja Perčić Nikola Vladimir 《哈尔滨工程大学学报(英文版)》 2026年第1期239-258,共20页
This paper investigates the reliability of internal marine combustion engines using an integrated approach that combines Fault Tree Analysis(FTA)and Bayesian Networks(BN).FTA provides a structured,top-down method for ... This paper investigates the reliability of internal marine combustion engines using an integrated approach that combines Fault Tree Analysis(FTA)and Bayesian Networks(BN).FTA provides a structured,top-down method for identifying critical failure modes and their root causes,while BN introduces flexibility in probabilistic reasoning,enabling dynamic updates based on new evidence.This dual methodology overcomes the limitations of static FTA models,offering a comprehensive framework for system reliability analysis.Critical failures,including External Leakage(ELU),Failure to Start(FTS),and Overheating(OHE),were identified as key risks.By incorporating redundancy into high-risk components such as pumps and batteries,the likelihood of these failures was significantly reduced.For instance,redundant pumps reduced the probability of ELU by 31.88%,while additional batteries decreased the occurrence of FTS by 36.45%.The results underscore the practical benefits of combining FTA and BN for enhancing system reliability,particularly in maritime applications where operational safety and efficiency are critical.This research provides valuable insights for maintenance planning and highlights the importance of redundancy in critical systems,especially as the industry transitions toward more autonomous vessels. 展开更多
关键词 Fault tree analysis Bayesian network RELIABILITY REDUNDANCY Internal combustion engine
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Cascading failure modeling and survivability analysis of weak-communication underwater unmanned swarm networks
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作者 Yifan Yuan Xiaohong Shen +3 位作者 Lin Sun Ke He Yongsheng Yan Haiyan Wang 《Defence Technology(防务技术)》 2026年第2期66-82,共17页
Cascading failures pose a serious threat to the survivability of underwater unmanned swarm networks(UUSNs),significantly limiting their service ability in collaborative missions such as military reconnaissance and env... Cascading failures pose a serious threat to the survivability of underwater unmanned swarm networks(UUSNs),significantly limiting their service ability in collaborative missions such as military reconnaissance and environmental monitoring.Existing failure models primarily focus on power grids and traffic systems,and don't address the unique challenges of weak-communication UUSNs.In UUSNs,cascading failure present a complex and dynamic process driven by the coupling of unstable acoustic channels,passive node drift,adversarial attacks,and network heterogeneity.To address these challenges,a directed weighted graph model of UUSNs is first developed,in which node positions are updated according to ocean-current-driven drift and link weights reflect the probability of successful acoustic transmission.Building on this UUSNs graph model,a cascading failure model is proposed that integrates a normal-failure-recovery state-cycle mechanism,multiple attack strategies,and routingbased load redistribution.Finally,under a five-level connectivity UUSNs scheme,simulations are conducted to analyze how dynamic topology,network load,node recovery delay,and attack modes jointly affect network survivability.The main findings are:(1)moderate node drift can improve survivability by activating weak links;(2)based-energy routing(BER)outperform based-depth routing(BDR)in harsh conditions;(3)node self-recovery time is critical to network survivability;(4)traditional degree-based critical node metrics are inadequate for weak-communication UUSNs.These results provide a theoretical foundation for designing robust survivability mechanisms in weak-communication UUSNs. 展开更多
关键词 Weak communication Underwater unmanned swarm networks(UUSNs) Link success probability Cascading failure Node self-recovery Survivability analysis
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Comparison of School Building Construction Costs Estimation Methods Using Regression Analysis, Neural Network, and Support Vector Machine 被引量:2
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作者 Gwang-Hee Kim Jae-Min Shin +1 位作者 Sangyong Kim Yoonseok Shin 《Journal of Building Construction and Planning Research》 2013年第1期1-7,共7页
Accurate cost estimation at the early stage of a construction project is key factor in a project’s success. But it is difficult to quickly and accurately estimate construction costs at the planning stage, when drawin... Accurate cost estimation at the early stage of a construction project is key factor in a project’s success. But it is difficult to quickly and accurately estimate construction costs at the planning stage, when drawings, documentation and the like are still incomplete. As such, various techniques have been applied to accurately estimate construction costs at an early stage, when project information is limited. While the various techniques have their pros and cons, there has been little effort made to determine the best technique in terms of cost estimating performance. The objective of this research is to compare the accuracy of three estimating techniques (regression analysis (RA), neural network (NN), and support vector machine techniques (SVM)) by performing estimations of construction costs. By comparing the accuracy of these techniques using historical cost data, it was found that NN model showed more accurate estimation results than the RA and SVM models. Consequently, it is determined that NN model is most suitable for estimating the cost of school building projects. 展开更多
关键词 ESTIMATING construction COSTS Regression analysis NEURAL network Support VECTOR MACHINE
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Exploring core symptoms and symptom clusters among patients with neuromyelitis optica spectrum disorder: A network analysis 被引量:1
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作者 Hao Liang Jiehan Chen +4 位作者 Lixin Wang Zhuyun Liu Haoyou Xu Min Zhao Xiaopei Zhang 《International Journal of Nursing Sciences》 2025年第2期152-160,共9页
Objectives To identify core symptoms and symptom clusters in patients with neuromyelitis optica spectrum disorder(NMOSD)by network analysis.Methods From October 10 to 30,2023,140 patients with NMOSD were selected to p... Objectives To identify core symptoms and symptom clusters in patients with neuromyelitis optica spectrum disorder(NMOSD)by network analysis.Methods From October 10 to 30,2023,140 patients with NMOSD were selected to participate in this online questionnaire survey.The survey tools included a general information questionnaire and a self-made NMOSD symptoms scale,which included the prevalence,severity,and distress of 29 symptoms.Cluster analysis was used to identify symptom clusters,and network analysis was used to analyze the symptom network and node characteristics and central indicators including strength centrality(r_(s)),closeness centrality(r_(c))and betweeness centrality(r_(b))were used to identify core symptoms and symptom clusters.Results The most common symptom was pain(65.7%),followed by paraesthesia(65.0%),fatigue(65.0%),easy awakening(63.6%).Regarding the burden level of symptoms,pain was the most burdensome symptom,followed by paraesthesia,easy awakening,fatigue,and difficulty falling asleep.Six clusters were identified:somatosensory,motor,visual,and memory symptom clusters,bladder and rectum symptom clusters,sleep symptoms clusters,and neuropsychological symptom clusters.Fatigue(r_(s)=12.39,r_(b)=68.00,r_(c)=0.02)was the most central and prominent bridge symptom,and motor symptom cluster(r_(s)=2.68,r_(c)=0.10)was the most central symptom cluster among the six clusters.Conclusions Our study demonstrated the necessity of symptom management targeting fatigue,pain,and motor symptom cluster in patients with NMOSD. 展开更多
关键词 Neuromyelitis optica spectrum disorder network analysis SYMPTOM Symptom clusters NURSING
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Possible Classifications of Social Network Addiction:A Latent Profile Analysis of Chinese College Students 被引量:1
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作者 Lin Luo Junfeng Yuan +4 位作者 Yanling Wang Rui Zhu HuilinXu Siyuan Bi Zhongge Zhang 《International Journal of Mental Health Promotion》 2025年第6期863-876,共14页
Objectives:SocialNetworkAddiction(SNA)is becoming increasingly prevalent among college students;however,there remains a lack of consensus regarding the measurement tools and their optimal cutoff score.This study aims ... Objectives:SocialNetworkAddiction(SNA)is becoming increasingly prevalent among college students;however,there remains a lack of consensus regarding the measurement tools and their optimal cutoff score.This study aims to validate the 21-item SocialNetwork Addiction Scale-Chinese(SNAS-C)in its Chinese version and to determine its optimal cutoff score for identifying potential SNA cases within the college student population.Methods:A crosssectional survey was conducted,recruiting 3387 college students.Latent profile analysis(LPA)and receiver operating characteristic(ROC)curve analysis were employed to establish the optimal cutoff score for the validated 21-item SNAS-C.Results:Three profile models were selected based on multiple statistical criteria,classifying participants into low-risk,moderate-risk,and high-risk groups.The highest-risk group was defined as“positive”for SNA,while the remaining groups were considered“negative”,serving as the reference standard for ROC analysis.The optimal cutoff score was determined to be 72(sensitivity:98.2%,specificity:96.86%),with an overall classification accuracy of 97.0%.The“positive”group reported significantly higher frequency of social network usage,greater digitalmedia dependence scores,and a higher incidence of network addiction.Conclusion:This study identified the optimal cutoff score for the SNAS-C as≥72,demonstrating high sensitivity,specificity,and diagnostic accuracy.This threshold effectively distinguishes between high-risk and low-risk SNA. 展开更多
关键词 Social network addiction mental health latent profile analysis(LPA) receiver operating characteristic(ROC) social networking addiction scale-Chinese(SNAS-C)
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Resting-state brain network remodeling after different nerve reconstruction surgeries:a functional magnetic resonance imaging study in brachial plexus injury rats
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作者 Yunting Xiang Xiangxin Xing +6 位作者 Xuyun Hua Yuwen Zhang Xin Xue Jiajia Wu Mouxiong Zheng He Wang Jianguang Xu 《Neural Regeneration Research》 SCIE CAS 2025年第5期1495-1504,共10页
Distinct brain remodeling has been found after different nerve reconstruction strategies,including motor representation of the affected limb.However,differences among reconstruction strategies at the brain network lev... Distinct brain remodeling has been found after different nerve reconstruction strategies,including motor representation of the affected limb.However,differences among reconstruction strategies at the brain network level have not been elucidated.This study aimed to explore intranetwork changes related to altered peripheral neural pathways after different nerve reconstruction surgeries,including nerve repair,endto-end nerve transfer,and end-to-side nerve transfer.Sprague–Dawley rats underwent complete left brachial plexus transection and were divided into four equal groups of eight:no nerve repair,grafted nerve repair,phrenic nerve end-to-end transfer,and end-to-side transfer with a graft sutured to the anterior upper trunk.Resting-state brain functional magnetic resonance imaging was obtained 7 months after surgery.The independent component analysis algorithm was utilized to identify group-level network components of interest and extract resting-state functional connectivity values of each voxel within the component.Alterations in intra-network resting-state functional connectivity were compared among the groups.Target muscle reinnervation was assessed by behavioral observation(elbow flexion)and electromyography.The results showed that alterations in the sensorimotor and interoception networks were mostly related to changes in the peripheral neural pathway.Nerve repair was related to enhanced connectivity within the sensorimotor network,while end-to-side nerve transfer might be more beneficial for restoring control over the affected limb by the original motor representation.The thalamic-cortical pathway was enhanced within the interoception network after nerve repair and end-to-end nerve transfer.Brain areas related to cognition and emotion were enhanced after end-to-side nerve transfer.Our study revealed important brain networks related to different nerve reconstructions.These networks may be potential targets for enhancing motor recovery. 展开更多
关键词 brain functional networks end-to-end nerve transfer end-to-side nerve transfer independent component analysis nerve repair peripheral plexus injury resting-state functional connectivity
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Aspect-Level Sentiment Analysis of Bi-Graph Convolutional Networks Based on Enhanced Syntactic Structural Information
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作者 Junpeng Hu Yegang Li 《Journal of Computer and Communications》 2025年第1期72-89,共18页
Aspect-oriented sentiment analysis is a meticulous sentiment analysis task that aims to analyse the sentiment polarity of specific aspects. Most of the current research builds graph convolutional networks based on dep... Aspect-oriented sentiment analysis is a meticulous sentiment analysis task that aims to analyse the sentiment polarity of specific aspects. Most of the current research builds graph convolutional networks based on dependent syntactic trees, which improves the classification performance of the models to some extent. However, the technical limitations of dependent syntactic trees can introduce considerable noise into the model. Meanwhile, it is difficult for a single graph convolutional network to aggregate both semantic and syntactic structural information of nodes, which affects the final sentence classification. To cope with the above problems, this paper proposes a bi-channel graph convolutional network model. The model introduces a phrase structure tree and transforms it into a hierarchical phrase matrix. The adjacency matrix of the dependent syntactic tree and the hierarchical phrase matrix are combined as the initial matrix of the graph convolutional network to enhance the syntactic information. The semantic information feature representations of the sentences are obtained by the graph convolutional network with a multi-head attention mechanism and fused to achieve complementary learning of dual-channel features. Experimental results show that the model performs well and improves the accuracy of sentiment classification on three public benchmark datasets, namely Rest14, Lap14 and Twitter. 展开更多
关键词 Aspect-Level Sentiment analysis Sentiment Knowledge Multi-Head Attention Mechanism Graph Convolutional networks
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The Fundamental Construction and Social Development of China’s Network Society
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作者 Xie Jungui 《Contemporary Social Sciences》 2025年第5期122-139,共18页
The idea of a network society was introduced by Western sociologists at the end of the 20th century after in-depth research was conducted from perspectives such as informationalism.Influenced by these developments,the... The idea of a network society was introduced by Western sociologists at the end of the 20th century after in-depth research was conducted from perspectives such as informationalism.Influenced by these developments,the concept of constructing a network society also emerged in China.Over the past 30 years,China has made significant progress and achievements in constructing a network society,both in terms of its fundamental construction and social development.It is important that these advancements be summarized and reviewed.China’s network society construction can be divided into two relatively independent yet interconnected components,based on their focal points:its foundational infrastructure and its social development.These two components of China’s network society are managed by different departments.China has integrated the fundamental construction of its network society with the social development of its network society,thereby achieving unified planning,collaborative advancement,and coordinated development.This approach aims to harmonize two aspects:building China’s cyberspace strength and contributing to Chinese informatization,thereby advancing Chinese modernization. 展开更多
关键词 network society information society INFRASTRUCTURE social development network society construction building China’s cyberspace strength network society planning
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Optimization of Park System in Haidian District,Beijing Based on Social Network Analysis
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作者 WU Haotian CAO Ying 《Journal of Landscape Research》 2025年第2期11-16,共6页
The construction of“park cities”requires a systematic thinking to coordinate the networked development of park system and break through the limitation of emphasizing scale and grade and neglecting dynamic correlatio... The construction of“park cities”requires a systematic thinking to coordinate the networked development of park system and break through the limitation of emphasizing scale and grade and neglecting dynamic correlation in traditional planning.Taking Haidian District of Beijing as an example,the social network analysis method is introduced to construct the network model of park green spaces.Through indicators such as clustering coefficient,network density and node centrality,the characteristics of its spatial structure and hierarchical relationship are analyzed.It is found that the network integrity presents the characteristics of“highly local concentration and global fragmentation”,fragmented park green space network and missing spatial connection,isolated clusters and collaborative failure,as well as the spatial mismatch between population and resource supply and demand.Hierarchical issues include“structural imbalance and functional disorder”,disorder between network hierarchy and park level,misalignment of functional hierarchy leading to weakened network risk resistance capacity,and a relatively dense distribution of core nodes,etc.In response to the above problems,a multi-level spatial intervention strategy should be adopted to solve the overall problem of the network.Meanwhile,it is needed to clarify the positioning of a park itself and improve the hierarchical system,so as to construct a multi-level and multi-scale park green space network,contribute to the construction of a park city,and provide residents with more diverse activity venues. 展开更多
关键词 Urban park system Social network analysis Haidian District BEIJING Park network structure
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Analysis of Cost Control Strategies in Green Building Construction Processes
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作者 Junwen Zeng 《Journal of Architectural Research and Development》 2025年第6期60-65,共6页
Green building construction typically incurs higher costs than conventional methods.To facilitate broader adoption by construction entities,cost optimization is essential.Firms must align with technological advancemen... Green building construction typically incurs higher costs than conventional methods.To facilitate broader adoption by construction entities,cost optimization is essential.Firms must align with technological advancements,judiciously apply emerging technologies,and ensure resource efficiency through context-specific strategies.Proactive and precise scheduling is critical to avert delays from unforeseen events.Additionally,construction units should enhance on-site safety training,promote mastery of innovative techniques,and foster environmental awareness among personnel.Finally,companies ought to capitalize on government incentives for green materials while adopting bulk procurement from local sources to minimize transportation costs and secure lower unit prices. 展开更多
关键词 construction process Cost control Strategy analysis
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Distribution of Traditional Chinese Medicine Syndromes and Syndrome Elements of Chronic Heart Failure Based on Network Analysis and Hierarchical Cluster Analysis
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作者 ZHOU Yi HUANG Pinxian +1 位作者 LI Xiaoqian HE Jiancheng 《Chinese Medicine and Culture》 2025年第1期50-60,共11页
Traditional Chinese medicine(TCM)has played a significant role in the prevention and treatment of chronic heart failure(CHF).To study TCM diagnosis of CHF,a total of 278 Chinese clinical research articles on the study... Traditional Chinese medicine(TCM)has played a significant role in the prevention and treatment of chronic heart failure(CHF).To study TCM diagnosis of CHF,a total of 278 Chinese clinical research articles on the study of CHF syndromes in recent 40 years retrieved from Web of Science,Scopus,Pub Med,Embase,CNKI,Wanfang Data,Cq VIP,and Sino Med.According to cumulative frequency analysis,network analysis,and hierarchical cluster analysis,the study found the distribution of CHF syndromes was syndrome of qi deficiency with blood stasis,syndrome of qi and yin deficiency,syndrome of yang deficiency with water flooding,syndrome of heart blood stasis obstruction,syndrome of turbid phlegm,and syndrome of collapse due to primordial yang deficiency.The syndrome elements on location of illness were heart,kidney,lung,and spleen.The syndrome elements on nature of illness were qi deficiency,blood stasis,yang deficiency,yin deficiency,water retention,and turbid phlegm.These findings can provide reference to the research on diagnosis and treatment of CHF,and contribute to the study on syndrome standardization and objective research of TCM diagnosis. 展开更多
关键词 Chronic heart failure Traditional Chinese medicine Hierarchical cluster analysis network analysis SYNDROME Syndrome differentiation Syndrome element
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Drivers influencing the adoption of cryptocurrency: a social network analysis approach
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作者 K.Kajol Srijanani Devarakonda +1 位作者 Ranjit Singh H.Kent Baker 《Financial Innovation》 2025年第1期2103-2127,共25页
Cryptocurrency has gained popularity as a potential new global payment method.It has the potential to be faster,cheaper,and more secure than existing payment networks,making it a game-changer in the global economy.How... Cryptocurrency has gained popularity as a potential new global payment method.It has the potential to be faster,cheaper,and more secure than existing payment networks,making it a game-changer in the global economy.However,more research is needed to identify the factors driving cryptocurrency adoption and understand its impact.We use social network analysis(SNA)to identify the influencing factors and reveal the impact of each on cryptocurrency adoption.Our analysis initially revealed 44 influential factors,which were later reduced to 25 factors,each exerting a different influence.Based on the SNA,we classify these factors into highly,moderately,and least influential categories.Discomfort and optimism are the most influential determinants of adoption.Moderately influential factors include trust,risk,relative advantage,social influence,and perceived behavioral control.Price/value,facilitating conditions,compatibility,and usefulness are the least influential.The factors affecting cryptocurrency adoption are interdependent.Our findings can help policymakers understand the factors influencing cryptocurrency adoption and aid in developing appropriate legal frameworks for cryptocurrency use. 展开更多
关键词 Cryptocurrency Social network analysis(SNA) Systematic review Delphi technique
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Psychometric Properties of the Shortened Committed Action Questionnaire(CAQ-8):Evidence from Classical Test Theory and Network Analysis
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作者 Haiyan Hu Shuanghu Fang +1 位作者 Qilin Zheng Dongyan Ding 《International Journal of Mental Health Promotion》 2025年第1期65-76,共12页
Objectives:This study aimed to assess the reliability and validity of the abbreviated Committed Action Questionnaire(CAQ-8)in a cohort of 1635 Chinese university students.Methods:Participants completed the Chinese ver... Objectives:This study aimed to assess the reliability and validity of the abbreviated Committed Action Questionnaire(CAQ-8)in a cohort of 1635 Chinese university students.Methods:Participants completed the Chinese version of the CAQ-8 along with other standardized measures,including the Acceptance and Action Questionnaire-II(AAQ-II),the Valuing Questionnaire(VQ),the Satisfaction with Life Scale(SWLS),the Depression Anxiety Stress Scales(DASS-21),and the World Health Organization Fiveitem Well-Being Index(WHO-5).A retest was conducted one month later with 300 valid responses.Results:Exploratory factor analysis(n=818)identified a 2-factor structure,confirmed through validated factor analysis(n=817),showing good fit indices(CFI=0.990,RMSEA=0.040).Measurement equivalence across genders was established.The CAQ-8 showed significant positive correlations with life satisfaction,mental health,and values,and negative correlations with depression,anxiety,stress,and experiential avoidance.The scale demonstrated good internal consistency(Cronbach’sα=0.76)and retest reliability(ICC=0.70).Network analysis confirmed the robustness of the 2-factor model,with item 4 in CAQ-8 identified as a core item.Conclusion:The CAQ-8 is a reliable and valid tool for measuring committed action within the psychological flexibility model in Chinese populations. 展开更多
关键词 Acceptance and commitment therapy psychological flexibility committed action network analysis RELIABILITY validity
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Unveiling core acupoints in acupuncture treatment for primary depressive disorder:integrating data mining and network acupuncture-based analysis
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作者 Siyu LIU Xinnan LUOa Jiayun XIE +2 位作者 Miqun ZHOU Xiaona HU Shuang SONG 《Digital Chinese Medicine》 2025年第4期504-516,共13页
Objective To identify core acupoint patterns and elucidate the molecular mechanisms of acupuncture for primary depressive disorder(PDD)through data mining and network analysis.Methods A comprehensive literature search... Objective To identify core acupoint patterns and elucidate the molecular mechanisms of acupuncture for primary depressive disorder(PDD)through data mining and network analysis.Methods A comprehensive literature search was conducted across PubMed,Embase,Ovid Technologies(OVID),Web of Science,Cochrane Library,China National Knowledge Infrastructure(CNKI),China National Knowledge Infrastructure Database(VIP),Wanfang Data,and SinoMed Database from database foundation to January 31,2025,for clinical studies on acupuncture treatment of PDD.Descriptive statistics,high-frequency acupoint analysis,degree and betweenness centrality evaluation,and core acupoint prescription mining identified predominant therapeutic combinations for PDD.Network acupuncture was used to predict therapeutic target for the core acupoint prescription.Subsequent protein-protein interaction(PPI)network and molecular complex detection(MCODE)analyses were conducted to identify the key targets and functional modules.Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)analyses explored the underlying biological mechanisms of the core acupoint prescription in treating PDD.Results A total of 57 acupoint prescriptions underwent systematic analysis.The core therapeutic combinations comprised Baihui(GV20),Yintang(GV29),Neiguan(PC6),Hegu(LI4),and Shenmen(HT7).Network acupuncture analysis identified 88 potential therapeutic targets(79 overlapping with PDD),while PPI network analysis revealed central regulatory nodes,including interleukin(IL)-6,IL-1β,tumor necrosis factor(TNF)-α,toll-like receptor 4(TLR4),IL-10,brain-derived neurotrophic factor(BDNF),transforming growth factor(TGF)-β1,C-XC motif chemokine ligand 10(CXCL10),mitogen-activated protein kinase 3(MAPK3),and nitric oxide synthase 1(NOS1).MCODE-based modular analysis further elucidated three functionally coherent clusters:inflammation-homeostasis(score=6.571),plasticity-neurotransmission(score=3.143),and oxidative stress(score=3.000).GO and KEGG analyses demonstrated significant enrichment of the MAPK,phosphoinositide 3-kinase/protein kinase B(PI3K/Akt),and hypoxia-inducible factor(HIF)-1 signaling pathways.These mechanistic insights suggested that the antidepressant effects mediated through mechanisms of neuroinflammatory regulation,neuroplasticity restoration,and immune-oxidative stress homeostasis.Conclusion This study reveals that acupuncture alleviates depression through a multi-level mechanism,primarily involving the neuroinflammation suppression,neuroplasticity enhancement,and oxidative stress regulation.These findings systematically clarify the underlying mechanisms of acupuncture’s antidepressant effects and identify novel therapeutic targets for further mechanistic research. 展开更多
关键词 ACUPUNCTURE Primary depressive disorder(PDD) Data mining network acupuncture Association analysis
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Pharmacodynamic evaluation and network pharmacology analysis of a novel anti-heat stress Chinese herbal formula
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作者 Hanfei Wang Shuyi Xu +5 位作者 Haiyang Mao Boyu Wang Yanping Feng Awais Ihsan Shijun Li Xu Wang 《Animal Diseases》 2025年第2期248-266,共19页
Frequent extreme heat events around the world not only pose a major threat to human health but also cause significant economic losses to the livestock industry.The existing management practices are insufficient to ful... Frequent extreme heat events around the world not only pose a major threat to human health but also cause significant economic losses to the livestock industry.The existing management practices are insufficient to fully prevent heat stress with an urgent need to develop preventive medicines.The aim of this study was to develop an antiheat stress Chinese herbal formula(CHF)via big data analysis techniques and to evaluate its anti-heat stress effect and mechanism of action via pharmacodynamic evaluation and network pharmacology analysis.Many anti-heat stress CHFs were collected from the Chinese National Knowledge Infrastructure(CNKI)database.Three alternative CHFs were obtained via unsupervised entropy hierarchical clustering analysis,and the most effective CHF against heat stress,Shidi Jieshu decoction(SJD),was obtained by screening in a mouse heat stress model.In dry and hot environments,SJD significantly improved the heat tolerance of AA broilers by 4-6℃.In a humid and hot environment,pretreatment with 2%SJD resulted in 100%survival of Wenchang chickens at high temperatures.The main active ingredients of SJD were identified as muntjacoside E,timosaponin C,macrostemonoside H and mangiferin via ultraperformance liquid chromatography/mass spectrometry(UPLC/MS)and database comparison.The active ingredients of SJD were found to target tumor necrosis factor-α(TNF-α),signal transducer activator of transcription 3(STAT3)and epidermal growth factor receptor(EGFR).Finally,the safety of the new formulation was assessed in an acute oral toxicity study in rats.The SJDs developed in this study provide a new option for the prevention of heat stress in animal husbandry and offer new insights for further research on anti-heat stress. 展开更多
关键词 Hot weather Heat stress Big data analysis technology network pharmacology Molecular docking CHICKEN
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Cascading failure analysis of an interdependent network with power-combat coupling
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作者 WANG Yang TAO Junyong +2 位作者 ZHANG Yun’an BAI Guanghan DUI Hongyan 《Journal of Systems Engineering and Electronics》 2025年第2期405-422,共18页
Cutting off or controlling the enemy’s power supply at critical moments or strategic locations may result in a cascade failure,thus gaining an advantage in a war.However,the exist-ing cascading failure modeling analy... Cutting off or controlling the enemy’s power supply at critical moments or strategic locations may result in a cascade failure,thus gaining an advantage in a war.However,the exist-ing cascading failure modeling analysis of interdependent net-works is insufficient for describing the load characteristics and dependencies of subnetworks,and it is difficult to use for model-ing and failure analysis of power-combat(P-C)coupling net-works.This paper considers the physical characteristics of the two subnetworks and studies the mechanism of fault propaga-tion between subnetworks and across systems.Then the surviv-ability of the coupled network is evaluated.Firstly,an integrated modeling approach for the combat system and power system is predicted based on interdependent network theory.A heteroge-neous one-way interdependent network model based on proba-bility dependence is constructed.Secondly,using the operation loop theory,a load-capacity model based on combat-loop betweenness is proposed,and the cascade failure model of the P-C coupling system is investigated from three perspectives:ini-tial capacity,allocation strategy,and failure mechanism.Thirdly,survivability indexes based on load loss rate and network sur-vival rate are proposed.Finally,the P-C coupling system is con-structed based on the IEEE 118-bus system to demonstrate the proposed method. 展开更多
关键词 cascading failure survivability analysis interdepen-dent network power-combat(P-C)coupling.
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Sex and age differences in depression and anxiety networks among adolescents with idiopathic scoliosis:A network analysis
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作者 Shu-Wen Dong Lei Yang +8 位作者 Yi-Fan Lin Li-Wen Yang Dan Li Li-Wan Zhu Cai-Yun Zhang Yan-Zhi Li Wan-Xin Wang Ci-Yong Lu Bin Yan 《World Journal of Psychiatry》 2025年第3期261-271,共11页
BACKGROUND Depression and anxiety are prevalent psychological challenges among patients with adolescent idiopathic scoliosis(AIS),affecting individuals across both sex and age groups.AIM To explore the network structu... BACKGROUND Depression and anxiety are prevalent psychological challenges among patients with adolescent idiopathic scoliosis(AIS),affecting individuals across both sex and age groups.AIM To explore the network structure of depression and anxiety symptoms,with a focus on identifying differences at the symptom level between sex and age subgroups.METHODS A total of 1955 participants diagnosed with AIS aged 10-18 years were assessed using the Patient Health Questionnaire Depression Scale(PHO-9)and the Generalized Anxiety Disorder Scale(GAD-7),and 765 patients exhibiting PHQ-9 or GAD-7 scores ≥ 5 were enrolled in our study. Network analysis and network comparison tests were utilized toconstruct and compare the depression-anxiety symptoms networks among sex and age subgroups.RESULTSThe results revealed GAD3 “Excessive worry” and PHQ2 “Sad mood” were the most significant central symptomsin all subgroups, while “Sad mood” had higher strength than “Excessive worry” in the lower age group. In thenetwork comparisons, the female network exhibited tighter connectivity, especially on GAD6 “Irritability” andGAD2 “Uncontrollable worry”, while only PHQ3 “Sleep” and PHQ9 “Suicidal ideation” had differences at thelocal level in the lower age group.CONCLUSIONSeveral interventions targeting excessive worry and sad mood could reduce the risk of depression and anxietysymptoms in the AIS population. Furthermore, specific anxiety symptoms in females, along with sleep disturbancesand suicidal ideation in the lower age group, should be addressed at an early stage to prevent significantdisruptions in mental health trajectories. 展开更多
关键词 Adolescent idiopathic scoliosis network analysis Depression and anxiety symptoms Age difference Sex difference
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TGICP:A Text-Gated Interaction Network with Inter-Sample Commonality Perception for Multimodal Sentiment Analysis
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作者 Erlin Tian Shuai Zhao +3 位作者 Min Huang Yushan Pan Yihong Wang Zuhe Li 《Computers, Materials & Continua》 2025年第10期1427-1456,共30页
With the increasing importance of multimodal data in emotional expression on social media,mainstream methods for sentiment analysis have shifted from unimodal to multimodal approaches.However,the challenges of extract... With the increasing importance of multimodal data in emotional expression on social media,mainstream methods for sentiment analysis have shifted from unimodal to multimodal approaches.However,the challenges of extracting high-quality emotional features and achieving effective interaction between different modalities remain two major obstacles in multimodal sentiment analysis.To address these challenges,this paper proposes a Text-Gated Interaction Network with Inter-Sample Commonality Perception(TGICP).Specifically,we utilize a Inter-sample Commonality Perception(ICP)module to extract common features from similar samples within the same modality,and use these common features to enhance the original features of each modality,thereby obtaining a richer and more complete multimodal sentiment representation.Subsequently,in the cross-modal interaction stage,we design a Text-Gated Interaction(TGI)module,which is text-driven.By calculating the mutual information difference between the text modality and nonverbal modalities,the TGI module dynamically adjusts the influence of emotional information from the text modality on nonverbal modalities.This helps to reduce modality information asymmetry while enabling full cross-modal interaction.Experimental results show that the proposed model achieves outstanding performance on both the CMU-MOSI and CMU-MOSEI baseline multimodal sentiment analysis datasets,validating its effectiveness in emotion recognition tasks. 展开更多
关键词 Multi-modal sentiment analysis multi-modal fusion graph convolutional networks inter-sample commonality perception gated interaction
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