The process of engaging private sector in the provision of public infrastructure can improve economic value in service delivery and enable the government to utilize the capabilities and expertise held by private secto...The process of engaging private sector in the provision of public infrastructure can improve economic value in service delivery and enable the government to utilize the capabilities and expertise held by private sector. This has a positive impact on the public in terms of improving their well-being. This literature review attempts to compare the challenges encountered in implementation of PPP projects across the world, with a view to determining cross cutting challenges and recommendations for developing countries. A literature review was conducted for empirical studies focusing on construction projects. The studies are reviewed by analyzing the methodology used and conclusions made to identify the geographical study area, Public Private Partnership project financing model, emerging challenges and recommendation for future project management. The literature search was based on four keywords: construction projects, completion of construction projects, public private partnership, challenges in construction projects. Thus, a total of 11 empirical studies were identified for review in Europe, Asia and Africa. The review revealed that most risk factors affecting project completion can be categorized as human and organizational factors and unknown geotechnical conditions that were not known beforehand. Specifically, project owners’ interference was also attributable to delays with the delays having significant implications for project execution. Risks have great impact on the performance of construction projects because they affect their quality, time and cost. The general remedy to such potential risk factors is adoption of reliable prediction mechanisms which would estimate those factors using a probabilistic model that does not rely on expert judgments as they tend to be unreliable.展开更多
Genome assembly is a fundamental step in decoding the genetic information of life.Its significance lies in constructing a complete DNA sequence map of organisms,providing the foundation for elucidating the mechanisms ...Genome assembly is a fundamental step in decoding the genetic information of life.Its significance lies in constructing a complete DNA sequence map of organisms,providing the foundation for elucidating the mechanisms of species evolution,exploring gene functions,and identifying disease-related variations.However,some of the repetitive DNA sequences remain“dark materials”in the genome as they are difficult to reveal by the second-generation sequencing approaches.In recent years,breakthroughs in third-generation sequencing technologies have significantly improved the accuracy and continuity of genome assemblies,therefore,being able to resolve the“last piece of the puzzle”in the genome.展开更多
文摘The process of engaging private sector in the provision of public infrastructure can improve economic value in service delivery and enable the government to utilize the capabilities and expertise held by private sector. This has a positive impact on the public in terms of improving their well-being. This literature review attempts to compare the challenges encountered in implementation of PPP projects across the world, with a view to determining cross cutting challenges and recommendations for developing countries. A literature review was conducted for empirical studies focusing on construction projects. The studies are reviewed by analyzing the methodology used and conclusions made to identify the geographical study area, Public Private Partnership project financing model, emerging challenges and recommendation for future project management. The literature search was based on four keywords: construction projects, completion of construction projects, public private partnership, challenges in construction projects. Thus, a total of 11 empirical studies were identified for review in Europe, Asia and Africa. The review revealed that most risk factors affecting project completion can be categorized as human and organizational factors and unknown geotechnical conditions that were not known beforehand. Specifically, project owners’ interference was also attributable to delays with the delays having significant implications for project execution. Risks have great impact on the performance of construction projects because they affect their quality, time and cost. The general remedy to such potential risk factors is adoption of reliable prediction mechanisms which would estimate those factors using a probabilistic model that does not rely on expert judgments as they tend to be unreliable.
基金supported by the National Natural Science Foundation of China(32090034)Zhejiang Provincial Natural Science Foundation of China(2022XHSJJ001)+3 种基金Hangzhou City Leading Innovation and Entrepreneurship Team(TD2020004)“Pioneer”and“Leading Goose”Research and Development Program of Zhejiang(2024SSYS0033)Westlake Education FoundationWestlake Laboratory of Life Sciences and Biomedicine.
文摘Genome assembly is a fundamental step in decoding the genetic information of life.Its significance lies in constructing a complete DNA sequence map of organisms,providing the foundation for elucidating the mechanisms of species evolution,exploring gene functions,and identifying disease-related variations.However,some of the repetitive DNA sequences remain“dark materials”in the genome as they are difficult to reveal by the second-generation sequencing approaches.In recent years,breakthroughs in third-generation sequencing technologies have significantly improved the accuracy and continuity of genome assemblies,therefore,being able to resolve the“last piece of the puzzle”in the genome.
