A further reformulation of Naive Set Comprehension related to that proposed in ＂Resolving Insolubilia： Internal Inconsistency and the Reform of Naive Set Comprehension＂ （2012） is possible in which contradiction i...A further reformulation of Naive Set Comprehension related to that proposed in ＂Resolving Insolubilia： Internal Inconsistency and the Reform of Naive Set Comprehension＂ （2012） is possible in which contradiction is averted not by excluding sets such as the Russell Set but rather by treating sentences resulting from instantiation of such sets as the Russell Set in their own descriptions as invalid. So the set of all sets that are not members of thernselves in this further revision is a valid set but the claim that that set is or is not a member of itself is not validly expressible. Such an approach to set comprehension results in a set ontology co-extensive with that permitted by the Naive Set Comprehension Principle itself. This approach （that may be called Revised Set Comprehension Ⅱ） has as strong a claim to consistency as that formulated in ＂Resolving Insolubilia： Internal Inconsistency and the Reform of Naive Set Comprehension.＂展开更多
目的分析基于3D打印技术的吸入制剂仿生学研究现状,并评价吸入制剂在体内的空气动力学行为,提高其药物疗效和临床前药学研究的效率。方法以中国知网、万方、Web of Science数据库中的数据为基础,梳理已有研究中吸入制剂对3D打印技术的...目的分析基于3D打印技术的吸入制剂仿生学研究现状,并评价吸入制剂在体内的空气动力学行为,提高其药物疗效和临床前药学研究的效率。方法以中国知网、万方、Web of Science数据库中的数据为基础,梳理已有研究中吸入制剂对3D打印技术的运用情况,并深入分析其在提升药物疗效和加速临床前药学研究的潜力。结果3D打印技术仿生学在吸入制剂中的应用目前主要用于药物递送系统和药物靶点设计的研究,可提高给药效率和药物沉积率,并可通过构建呼吸道仿生模型模拟真实的呼吸道结构和生理环境,系统评估吸入制剂在肺部的沉积率和空气动力学行为,探索药物粒子的沉积规律。结论3D打印技术在吸入制剂的实践运用、仿生真实性等方面还存在不足,但为吸入制剂的研发提供了更真实的研究方法,这一研究成果有望显著提高吸入制剂的一致性评价和创新研发效率。展开更多
文摘A further reformulation of Naive Set Comprehension related to that proposed in ＂Resolving Insolubilia： Internal Inconsistency and the Reform of Naive Set Comprehension＂ （2012） is possible in which contradiction is averted not by excluding sets such as the Russell Set but rather by treating sentences resulting from instantiation of such sets as the Russell Set in their own descriptions as invalid. So the set of all sets that are not members of thernselves in this further revision is a valid set but the claim that that set is or is not a member of itself is not validly expressible. Such an approach to set comprehension results in a set ontology co-extensive with that permitted by the Naive Set Comprehension Principle itself. This approach （that may be called Revised Set Comprehension Ⅱ） has as strong a claim to consistency as that formulated in ＂Resolving Insolubilia： Internal Inconsistency and the Reform of Naive Set Comprehension.＂
文摘目的分析基于3D打印技术的吸入制剂仿生学研究现状,并评价吸入制剂在体内的空气动力学行为,提高其药物疗效和临床前药学研究的效率。方法以中国知网、万方、Web of Science数据库中的数据为基础,梳理已有研究中吸入制剂对3D打印技术的运用情况,并深入分析其在提升药物疗效和加速临床前药学研究的潜力。结果3D打印技术仿生学在吸入制剂中的应用目前主要用于药物递送系统和药物靶点设计的研究,可提高给药效率和药物沉积率,并可通过构建呼吸道仿生模型模拟真实的呼吸道结构和生理环境,系统评估吸入制剂在肺部的沉积率和空气动力学行为,探索药物粒子的沉积规律。结论3D打印技术在吸入制剂的实践运用、仿生真实性等方面还存在不足,但为吸入制剂的研发提供了更真实的研究方法,这一研究成果有望显著提高吸入制剂的一致性评价和创新研发效率。
