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Artificial intelligence in personalized cardiology treatment 被引量:1
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作者 Abbas Mohammadi Sheida Shokohyar 《Digital Chinese Medicine》 2025年第1期28-35,共8页
Cardiovascular diseases are the leading cause of death,requiring innovative approaches for prevention,diagnosis,and treatment.Personalized medicine customizes interventions according to individual characteristics,with... Cardiovascular diseases are the leading cause of death,requiring innovative approaches for prevention,diagnosis,and treatment.Personalized medicine customizes interventions according to individual characteristics,with artificial intelligence(AI)playing a key role in analyzing complex data to improve diagnostic accuracy,predict outcomes,and optimize therapies.AI can identify patterns in imaging and biomarkers,facilitating the earlier detection of medical conditions.Wearable devices and health applications facilitate continuous monitoring and personalized care.Emerging fields such as digital Chinese medicine offer additional perspectives by integrating traditional diagnostic principles with modern digital tools,contributing to holistic and individualized cardiovascular care.This study examines the advancements and challenges in personalized cardiovascular medicine,highlighting the need to address issues such as data privacy,algorithmic bias,and accessibility to promote the equitable application of personalized medicine. 展开更多
关键词 Artificial intelligence(AI) Machine learning Personalized medicine CARDIOLOGY Patient outcomes Risk stratification Digital Chinese medicine Ethical considerations
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PGLYRP1 protein as a novel mediator of cellular dialogue in neuroinflammation
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作者 Anup Bhusal Won-Ha Lee Kyoungho Suk 《Neural Regeneration Research》 SCIE CAS 2025年第7期1993-1994,共2页
Neuroinflammation has been identified as a crucial element in several neurological disorders. Glial cells play a critical role in directing neuroinflammation, both in deleterious and beneficial ways.
关键词 INFLAMMATION considerably
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Navigating the ethical terrain:Off-label and experimental treatments in medical case reports
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作者 Madhan Jeyaraman Naveen Jeyaraman +1 位作者 Swaminathan Ramasubramanian Sangeetha Balaji 《World Journal of Methodology》 2025年第1期1-5,共5页
This article explores the ethical considerations surrounding the reporting of offlabel and experimental treatments in medical case reports,with a focus on fields such as oncology,psychiatry,and pediatrics.It emphasize... This article explores the ethical considerations surrounding the reporting of offlabel and experimental treatments in medical case reports,with a focus on fields such as oncology,psychiatry,and pediatrics.It emphasizes the balance between innovation and evidence-based medicine,highlighting the critical role of case reports in disseminating clinical experiences and advancing medical knowledge.The discussion delves into the ethical framework guiding case reporting,including principles of patient autonomy,informed consent,non-maleficence,beneficence,justice,and transparency.Challenges such as negative outcome reporting,commercial interests,and the balance between innovation and caution are examined.Recommendations for ethical vigilance,the development of comprehensive guidelines,and the role of regulatory bodies are proposed to ensure patient safety and uphold scientific integrity.The article concludes by underscoring the importance of a collaborative effort among clinicians,researchers,ethicists,and regulatory bodies to foster the responsible advancement of medical science while adhering to the highest ethical standards. 展开更多
关键词 Ethical considerations Patient autonomy Informed consent Non-maleficence BENEFICENCE TRANSPARENCY Evidence-based medicine
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The Future of Artificial Intelligence in the Face of Data Scarcity
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作者 Hemn Barzan Abdalla Yulia Kumar +4 位作者 Jose Marchena Stephany Guzman Ardalan Awlla Mehdi Gheisari Maryam Cheraghy 《Computers, Materials & Continua》 2025年第7期1073-1099,共27页
Dealing with data scarcity is the biggest challenge faced by Artificial Intelligence(AI),and it will be interesting to see how we overcome this obstacle in the future,but for now,“THE SHOW MUST GO ON!!!”As AI spread... Dealing with data scarcity is the biggest challenge faced by Artificial Intelligence(AI),and it will be interesting to see how we overcome this obstacle in the future,but for now,“THE SHOW MUST GO ON!!!”As AI spreads and transforms more industries,the lack of data is a significant obstacle:the best methods for teaching machines how real-world processes work.This paper explores the considerable implications of data scarcity for the AI industry,which threatens to restrict its growth and potential,and proposes plausible solutions and perspectives.In addition,this article focuses highly on different ethical considerations:privacy,consent,and non-discrimination principles during AI model developments under limited conditions.Besides,innovative technologies are investigated through the paper in aspects that need implementation by incorporating transfer learning,few-shot learning,and data augmentation to adapt models so they could fit effective use processes in low-resource settings.This thus emphasizes the need for collaborative frameworks and sound methodologies that ensure applicability and fairness,tackling the technical and ethical challenges associated with data scarcity in AI.This article also discusses prospective approaches to dealing with data scarcity,emphasizing the blend of synthetic data and traditional models and the use of advanced machine learning techniques such as transfer learning and few-shot learning.These techniques aim to enhance the flexibility and effectiveness of AI systems across various industries while ensuring sustainable AI technology development amid ongoing data scarcity. 展开更多
关键词 Data scarcity artificial intelligence application of artificial intelligence ethical considerations artificial general intelligence synthetic data
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Research on the Optimization of the Registration Classification of Biological Products in China
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作者 Li Zhiyi Huang Zhe 《Asian Journal of Social Pharmacy》 2025年第2期99-105,共7页
Objective To provide a theoretical basis for the adjustment of the registration classification of China’s biological products,and to establish a continuously improved registration classification system.Methods Based ... Objective To provide a theoretical basis for the adjustment of the registration classification of China’s biological products,and to establish a continuously improved registration classification system.Methods Based on literature research,the specific classification methods,classification principles and considerations of biological registration in China,the United States and the European Union were studied to form a complete comparative analysis.Results and Conclusion It is recommended that the division between therapeutic and preventive use should be removed from the registration classification of biologics.The therapeutic,preventive and diagnostic use of the product should be limited as part of the product specification,and the registration should be classified according to the development of biotechnology,innovation,modification and bio-similar drugs.In addition,the supervision of registration of advanced therapeutic products should be different from that of traditional biologics. 展开更多
关键词 biological product registration classification classification principle consideration factor
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Updates to the 2024 CSCO advanced non-small cell lung cancer guidelines
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作者 Jiale Wang Tianyu Qiu Shengxiang Ren 《Cancer Biology & Medicine》 2025年第2期77-82,共6页
In the past year,several advancements have been achieved in the treatment of advanced non-small cell lung cancer(NSCLC),particularly in the areas of immunotherapy and targeted therapy.These achievements have provided ... In the past year,several advancements have been achieved in the treatment of advanced non-small cell lung cancer(NSCLC),particularly in the areas of immunotherapy and targeted therapy.These achievements have provided additional options for improving patient outcomes.The 2024 Chinese Society of Clinical Oncology Guidelines for NSCLC(CSCO NSCLC),a key reference for clinical oncologists in China,have incorporated current global research and adapted recommendations for applicability in real-world scenarios in China.This update covers not only patient selection,efficacy,and safety,but also considers economics,and accessibility,with an aim to provide more precise and comprehensive treatment guidance for Chinese oncologists. 展开更多
关键词 csco guidelines targeted therapythese advanced non small cell lung cancer clinical oncologists IMMUNOTHERAPY ACCESSIBILITY economic considerations targeted therapy
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Legal Framework and Its Practice for the Normative Development of Generative AI in China
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作者 Chen Bing Li Guozhen 《科技与法律(中英文)》 2025年第4期130-148,共19页
Currently,generative AI technologies and services worldwide are experiencing explosive growth.While driving technological innovation and productivity advancement in the social economy,they also precipitate multiple le... Currently,generative AI technologies and services worldwide are experiencing explosive growth.While driving technological innovation and productivity advancement in the social economy,they also precipitate multiple le-gal risks,ethical breaches in technology,and social governance challenges.Distinct regulatory pathways have emerged internationally:the EU promotes a rigid governance system through a unified regulatory framework and centralized oversight mechanisms,though concurrently exhibiting a trend of deferred legal application;the United States adopts an advocacy-based regulatory strategy combining principled guidance with corporate self-compliance;the United King-dom implements a non-mandatory principled framework establishing a compromise-based governance model.Grounded in China's strategic imperative to engage in global AI competition and informed by international experi-ences,the legal governance framework for generative AI must incorporate practical legislative imperatives,anchored in the dynamic adaptation between technological iteration and legal regulation,alongside the recalibration of developmen-tal efficacy against security risks.This necessitates establishing tiered safety thresholds and controllability require-ments within the governance architecture.Accordingly,there is an urgent need to enhance institutional provision and policy coordination,construct a multi-stakeholder long-term mechanism integrating administrative supervision,indus-try self-regulation,and technical governance,and formulate scenario-specific liability rules covering the entire life cycle from R&D to deployment-thereby avoiding arbitrary legislative uniformity.The ultimate objective is to forge a comprehensive governance ecosystem characterized by trustworthiness and security as its foundation,and prudence,in-clusiveness,and dynamic adaptability as its defining features. 展开更多
关键词 generative AI risk extraterritorial rule of law rule of law consideration practice architecture
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Strategic framework to advance scientific innovation in clinically dominant diseases in traditional Chinese medicine:Plasma cell mastitis
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作者 TU Siyuan YIN Yulian +9 位作者 XU Jiachen CHEN Hongfeng WU Xueqing JIN Yiting ZHU Wei FU Na SHENG Jiayu LIU Xiaofei CHU Chengyu YE Meina 《World Journal of Integrated Traditional and Western Medicine》 2025年第3期110-122,共13页
In accordance with the Guiding Opinions of the Central Committee of the Communist Party of China and the State Council on Promoting the Inheritance and Innovation of Traditional Chinese Medicine(TCM),the China Associa... In accordance with the Guiding Opinions of the Central Committee of the Communist Party of China and the State Council on Promoting the Inheritance and Innovation of Traditional Chinese Medicine(TCM),the China Association of Chinese Medicine(CACM)organized multidisciplinary symposia on TCM-dominant diseases with the aim of advancing research on clinically dominant diseases in TCM,supporting specialty development,cultivating clinical talent,developing strategic plans for national science,and fostering academic innovation.The 42nd Academic Salon on Clinically Dominant Diseases,which was convened in Shanghai on 24 November 2024,brought together TCM experts,Western medicine experts,and interdisciplinary researchers for in-depth discussions on the current status,strengths,and limitations of and strategies to improve the integrated diagnosis and treatment of plasma cell mastitis(PCM).While consensus had been reached on recommendations for TCM and integrated approaches,detailed research pathways remain to be developed.In this work,we systematically examine the pathogenesis of and clinical management challenges related to PCM.Building on the therapeutic strengths of TCM,we propose 5 prioritized research domains with corresponding scientific planning:(1)Early identification and intervention strategies for PCM;(2)Optimization of TCM syndrome differentiation systems for PCM;(3)Standardization of efficient evaluation metrics for PCM therapies;(4)Mechanistic studies on the pathogenesis of PCM and TCM therapeutic targets;(5)Prevention protocols and complication management frameworks for PCM.We further delineate recommended research directions,anticipated outcomes,value propositions,and funding priorities.The aim of this research model,which was derived from the PCM-focused academic salon series,is to advance the development of high-quality TCM practices by informing national scientific planning,innovative drug development,research priorities,and the formulation of clinical guidelines. 展开更多
关键词 Plasma cell mastitis TCM-dominant disease Integrated traditional Chinese and Western medicine Scientific considerations
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藏文动词使用及其规范化思考
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作者 扎西顿珠 《西藏大学学报(藏文版)》 CSSCI 2024年第4期90-113,共24页
Verbs in Tibetan hold an important position in Tibetan grammar and spellings.As complicated theories and wide range of application,some mistakes of actual use are easily made such as disobeying the Linguistic theories... Verbs in Tibetan hold an important position in Tibetan grammar and spellings.As complicated theories and wide range of application,some mistakes of actual use are easily made such as disobeying the Linguistic theories and non-canonical use,which can be found in the academic journals and literary works.The problems found in the actual use of verbs become an obstacle of proper delivery of authors'message to the readers.These problems received a great attention from the academic circle,though yet to conduct thorough research.This article discusses the complicated problems focusing on the issues such as the differences of the transitive verbs and intransitive verbs and actual usage of the verbs,three tenses of the verbs and actual usage,formation of the gerund,the use of negative words on the verbs. 展开更多
关键词 Tibetan verbs actual use standardisation CONSIDERATION
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Systematic Literature Review on Cloud Computing Security: Threats and Mitigation Strategies
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作者 Sina Ahmadi 《Journal of Information Security》 2024年第2期148-167,共20页
Cloud computing plays a significant role in modern information technology, providing organizations with numerous benefits, including flexibility, scalability, and cost-efficiency. However, it has become essential for ... Cloud computing plays a significant role in modern information technology, providing organizations with numerous benefits, including flexibility, scalability, and cost-efficiency. However, it has become essential for organizations to ensure the security of their applications, data, and cloud-based networks to use cloud services effectively. This systematic literature review aims to determine the latest information regarding cloud computing security, with a specific emphasis on threats and mitigation strategies. Additionally, it highlights some common threats related to cloud computing security, such as distributed denial-of-service (DDoS) attacks, account hijacking, malware attacks, and data breaches. This research also explores some mitigation strategies, including security awareness training, vulnerability management, security information and event management (SIEM), identity and access management (IAM), and encryption techniques. It discusses emerging trends in cloud security, such as integrating artificial intelligence (AI) and machine learning (ML), serverless computing, and containerization, as well as the effectiveness of the shared responsibility model and its related challenges. The importance of user awareness and the impact of emerging technologies on cloud security have also been discussed in detail to mitigate security risks. A literature review of previous research and scholarly articles has also been conducted to provide insights regarding cloud computing security. It shows the need for continuous research and innovation to address emerging threats and maintain a security-conscious culture in the company. 展开更多
关键词 Cloud Security Threat Analysis Mitigation Strategies Emerging Trends Ethi-cal Considerations Data Analysis
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The crucial role of surveillance in disease outbreak control:a comprehensive review
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作者 Gehendra Mahara Reg Bhandari Dandan Zhou 《汕头大学医学院学报》 2024年第3期187-192,共6页
Surveillance systems are vital for detecting,managing,and mitigating infectious disease outbreaks.This review highlights the importance of modern technologies like AI and big data in enhancing surveillancecapabilities... Surveillance systems are vital for detecting,managing,and mitigating infectious disease outbreaks.This review highlights the importance of modern technologies like AI and big data in enhancing surveillancecapabilities.It underscores the need for global collaboration and examines the role of surveillance in diseases likeinfluenza,Ebola,and COVID-19.Technological innovations such as geospatial mapping and wearable healthdevices are transforming disease control,though they raise ethical concerns about privacy.Continuousadvancements and ethical safeguards are crucial for effective surveillance and global health protection. 展开更多
关键词 disease surveillance early detection global collaboration technological advancements ethical considerations
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One Health governance:theory,practice and ethics
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作者 Yinling Zhou Roger Frutos +1 位作者 Issam Bennis Mayumi D.Wakimoto 《Science in One Health》 2024年第1期95-103,共9页
One Health approach is a global public good(GPG)that invites governance to maximize the health of humans,animals,and the environment by shaping interdisciplinary and cross-sectoral collaboration.This paper explores th... One Health approach is a global public good(GPG)that invites governance to maximize the health of humans,animals,and the environment by shaping interdisciplinary and cross-sectoral collaboration.This paper explores the theoretical foundations,practical applications,and ethical considerations of the One Health governance architecture.At the theoretical level,One Health governance invites systems thinking and involves collaborative efforts among multiple stakeholders,applying across multi-layered scenarios and requires public-private partnership(PPP).This governance architecture transcends traditional anthropocentrism and shifts towards ecocentrism,highlighting the integrity of ecosystems and the deep prevention of diseases.Selected case studies illustrate the implementation of One Health initiatives,such as shared water resources,disease surveillance programmes,and sustainable environmental health interventions,demonstrating the added value of a collaborative efforts across sectors and regions.Ethical considerations are integral to decision-making and actions of One Health governance,with a focus on equity,inclusivity and accountability,providing moral guidelines to prioritize the health of vulnerable populations and ecosystems.Through these efforts,One Health governance is expected to improve public health globally,promote sustainable development,and achieve a harmonious coexistence of human,animal,and environmental health. 展开更多
关键词 One Health governance Theoretical framework Multi-sectoral collaboration Ethical considerations Global health Sustainable development
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Illuminating the Future
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作者 GE LIJUN 《ChinAfrica》 2024年第9期46-47,共2页
Two hydroelectric power stations built by China have considerably improved the quality of life for Guineans.For Sonkou Condé,28 September is an unforgettable date,because that is when the Kaléta dam,a projec... Two hydroelectric power stations built by China have considerably improved the quality of life for Guineans.For Sonkou Condé,28 September is an unforgettable date,because that is when the Kaléta dam,a project in which he was actively involved as an employee,was inaugurated.On this day,traditional Guinean music resounded over the construction site,accompanied by singing and dancing,which vividly displayed the joy and satisfaction of the local people. 展开更多
关键词 FORGET considerably VIVID
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Science Skill-Based Activities for Senior High School Students
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作者 Norman Ruelo Marquez 《Journal of Contemporary Educational Research》 2024年第12期291-298,共8页
Science enables students to seek knowledge and practice relevant scientific processes to provide meaningful solutions or information that can contribute to the development of society.This study aimed to create a scien... Science enables students to seek knowledge and practice relevant scientific processes to provide meaningful solutions or information that can contribute to the development of society.This study aimed to create a science learning activity for senior high school students that integrates learning skills in science such as information retrieval,scientific reading,data representation,scientific writing,and knowledge presentation.The subjects of this study,which was employed through purposive sampling,were Grade 12 STEM students and Science teachers from Batangas’2nd Congressional District-Area II.Documentary analysis was used to analyze the least mastered competencies in earth science,general biology,general chemistry,and general physics.An interview was also used to reinforce the data collection and analysis.The content’s relevancy influences the students’attitudes and interests,the teachers’teaching tactics,and the opportunity to learn collaboratively.The student’s learning skills in science were honed by the learning activities provided by their teacher.However,the students’data representation and knowledge presentation skills must be strengthened.Different pedagogical considerations may be emphasized in developing a learning activity to boost student engagement and achieve a better learning experience. 展开更多
关键词 Science learning competencies Attitudes and interest of STEM Learning skills in science Pedagogical consideration
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Validity Consideration in Designing an Oral English Test
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作者 崔丹 朱殿勇 王庆忠 《海外英语》 2014年第15期105-106,共2页
To make oral test accurately reflect the actual English spoken ability of candidates and play its role in guiding and promoting the improvement of English learners in the teaching, we must ensure that the design of sc... To make oral test accurately reflect the actual English spoken ability of candidates and play its role in guiding and promoting the improvement of English learners in the teaching, we must ensure that the design of scientific questions, the feasibility and validity of judgments to make an accurate and fair measurement of testers' language ability. 展开更多
关键词 Validity CONSIDERATION ORAL ENGLISH TEST ENGLISH s
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几组同根形容词的辨析
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作者 庄敏 《武夷学院学报》 1995年第3期58-62,共5页
在师专英语精读课教材(English,Learn It Better)的词汇练习中,笔者发现学生使用词的恰当派生形式来完成句子比较薄弱,尤其容易混淆一些同根形容词。本文拟就以下几组同根形容词的意义及其用法作一简要的辨析,以供英语学习者参考。
关键词 同根形容词 英语学习者 considerable 词根 精读课 后置定语 派生形式 师专英语 表语 worthy
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Validity Considerations in Designing an Oral English Test
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作者 曾小珊 《海外英语》 2012年第15期136-137,共2页
Speaking is the main purpose and most important skill for second language learning.This paper reviews the important validity considerations in designing a test,such as face validity,content validity,on the basis of wh... Speaking is the main purpose and most important skill for second language learning.This paper reviews the important validity considerations in designing a test,such as face validity,content validity,on the basis of which the author analyzes the oral test paper for the postgraduate entrance interview in Shaanxi University of Technology,thus putting forward some methods to improve the test paper. 展开更多
关键词 LANGUAGE TEST validity considerations ORAL ENGLISH
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加强语气的absolutely
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作者 唐国全 《大学英语》 2002年第6期48-48,共1页
关键词 加强语气 UNDERSTATEMENT 大学英语 时髦词 considerable 英语影响 固定表达 文化传统 正式文体 形容词
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钢板拉伸颈缩致断裂的应变局部化过程 被引量:4
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作者 任春影 万印 +1 位作者 初广香 王焕然 《塑性工程学报》 CAS CSCD 北大核心 2019年第1期150-155,共6页
利用MTS810实验机和Zwick HTM5020高速拉伸实验机对钢板进行不同应变率加载下的拉伸实验。利用数字图像相关性方法 (Digital Image Correlation,DIC)对拉伸过程中试件表面的应变场进行分析,得到标距段和颈缩区两个区域沿拉伸方向的平均... 利用MTS810实验机和Zwick HTM5020高速拉伸实验机对钢板进行不同应变率加载下的拉伸实验。利用数字图像相关性方法 (Digital Image Correlation,DIC)对拉伸过程中试件表面的应变场进行分析,得到标距段和颈缩区两个区域沿拉伸方向的平均应变历史曲线,其结果显示两曲线的分离时刻即为非局部化颈缩起始点;该分离时刻点与准静态下的Considere判据和动态下的Batra理论得到的颈缩点一致。DIC分析云图形象的显示了试样拉伸过程中从颈缩开始致断裂的应变局部化演化过程。提取云图中典型位置的应变分布曲线,获得不同时刻相同位置的真应变大小。此外,试样的局部断裂应变随应变率的增加而增大。 展开更多
关键词 数字图像 非局部化颈缩点 Considere判据 Batra判据 颈缩致断裂过程 局部断裂应变
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某车辐式张弦结构设计
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作者 吴浩 范重 +2 位作者 刘涛 张爱林 张艳霞 《建筑结构》 CSCD 北大核心 2021年第S01期440-446,共7页
大跨度张弦梁结构性能优越,在工程中得到广泛应用。结合一种具有涌泉造型的车辐式张弦结构,利用Rhino软件中的Grasshopper插件进行曲梁建模,采用Catenary运算器确定索形,有效提高了建模速度。考虑结构的最不利工况与初始缺陷的影响,对... 大跨度张弦梁结构性能优越,在工程中得到广泛应用。结合一种具有涌泉造型的车辐式张弦结构,利用Rhino软件中的Grasshopper插件进行曲梁建模,采用Catenary运算器确定索形,有效提高了建模速度。考虑结构的最不利工况与初始缺陷的影响,对结构进行了静力分析、动力特性分析、整体稳定计算和抗连续倒塌分析,计算结果满足相关规范标准要求。在车辐结构周边设置采用人字形支撑,通过关节轴承节点实现与主体结构的连接,对主体结构适应性较强。最后,提出对车辐式张弦结构的设计建议,可供类似工程参考。 展开更多
关键词 车辐式张弦结构 整体稳定 抗连续倒塌 关节轴承节点 Catenary运算器 Consider Collapse功能
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