The purpose of this paper is to study the theory of conservative estimating functions in nonlinear regression model with aggregated data. In this model, a quasi-score function with aggregated data is defined. When thi...The purpose of this paper is to study the theory of conservative estimating functions in nonlinear regression model with aggregated data. In this model, a quasi-score function with aggregated data is defined. When this function happens to be conservative, it is projection of the true score function onto a class of estimation functions. By constructing, the potential function for the projected score with aggregated data is obtained, which have some properties of log-likelihood function.展开更多
The structure and function of proteins are closely related, and protein structure decides its function, therefore protein structure prediction is quite important.β-turns are important components of protein secondary ...The structure and function of proteins are closely related, and protein structure decides its function, therefore protein structure prediction is quite important.β-turns are important components of protein secondary structure. So development of an accurate prediction method ofβ-turn types is very necessary. In this paper, we used the composite vector with position conservation scoring function, increment of diversity and predictive secondary structure information as the input parameter of support vector machine algorithm for predicting theβ-turn types in the database of 426 protein chains, obtained the overall prediction accuracy of 95.6%, 97.8%, 97.0%, 98.9%, 99.2%, 91.8%, 99.4% and 83.9% with the Matthews Correlation Coefficient values of 0.74, 0.68, 0.20, 0.49, 0.23, 0.47, 0.49 and 0.53 for types I, II, VIII, I’, II’, IV, VI and nonturn respectively, which is better than other prediction.展开更多
文摘The purpose of this paper is to study the theory of conservative estimating functions in nonlinear regression model with aggregated data. In this model, a quasi-score function with aggregated data is defined. When this function happens to be conservative, it is projection of the true score function onto a class of estimation functions. By constructing, the potential function for the projected score with aggregated data is obtained, which have some properties of log-likelihood function.
文摘The structure and function of proteins are closely related, and protein structure decides its function, therefore protein structure prediction is quite important.β-turns are important components of protein secondary structure. So development of an accurate prediction method ofβ-turn types is very necessary. In this paper, we used the composite vector with position conservation scoring function, increment of diversity and predictive secondary structure information as the input parameter of support vector machine algorithm for predicting theβ-turn types in the database of 426 protein chains, obtained the overall prediction accuracy of 95.6%, 97.8%, 97.0%, 98.9%, 99.2%, 91.8%, 99.4% and 83.9% with the Matthews Correlation Coefficient values of 0.74, 0.68, 0.20, 0.49, 0.23, 0.47, 0.49 and 0.53 for types I, II, VIII, I’, II’, IV, VI and nonturn respectively, which is better than other prediction.
