This paper studies consensus problems in weighted scale-free networks of asymmetrically coupled dynamical units, where the asymmetry in a given link is deter：mined by the relative degree of the involved nodes. It sho...This paper studies consensus problems in weighted scale-free networks of asymmetrically coupled dynamical units, where the asymmetry in a given link is deter：mined by the relative degree of the involved nodes. It shows that the asymmetry of interactions has a great effect on the consensus. Especially, when the interactions are dominant from higher- to lower-degree nodes, both the convergence speed and the robustness to communication delay are enhanced.展开更多
Early correction of childhood malocclusion is timely managing morphological,structural,and functional abnormalities at different dentomaxillofacial developmental stages.The selection of appropriate imaging examination...Early correction of childhood malocclusion is timely managing morphological,structural,and functional abnormalities at different dentomaxillofacial developmental stages.The selection of appropriate imaging examination and comprehensive radiological diagnosis and analysis play an important role in early correction of childhood malocclusion.This expert consensus is a collaborative effort by multidisciplinary experts in dentistry across the nation based on the current clinical evidence,aiming to provide general guidance on appropriate imaging examination selection,comprehensive and accurate imaging assessment for early orthodontic treatment patients.展开更多
Distributed Federated Learning(DFL)technology enables participants to cooperatively train a shared model while preserving the privacy of their local datasets,making it a desirable solution for decentralized and privac...Distributed Federated Learning(DFL)technology enables participants to cooperatively train a shared model while preserving the privacy of their local datasets,making it a desirable solution for decentralized and privacy-preserving Web3 scenarios.However,DFL faces incentive and security challenges in the decentralized framework.To address these issues,this paper presents a Hierarchical Blockchain-enabled DFL(HBDFL)system,which provides a generic solution framework for the DFL-related applications.The proposed system consists of four major components,including a model contribution-based reward mechanism,a Proof of Elapsed Time and Accuracy(PoETA)consensus algorithm,a Distributed Reputation-based Verification Mechanism(DRTM)and an Accuracy-Dependent Throughput Management(ADTM)mechanism.The model contribution-based rewarding mechanism incentivizes network nodes to train models with their local datasets,while the PoETA consensus algorithm optimizes the tradeoff between the shared model accuracy and system throughput.The DRTM improves the system efficiency in consensus,and the ADTM mechanism guarantees that the throughput performance remains within a predefined range while improving the shared model accuracy.The performance of the proposed HBDFL system is evaluated by numerical simulations,with the results showing that the system improves the accuracy of the shared model while maintaining high throughput and ensuring security.展开更多
The Internet of Things(IoT)has gained substantial attention in both academic research and real-world applications.The proliferation of interconnected devices across various domains promises to deliver intelligent and ...The Internet of Things(IoT)has gained substantial attention in both academic research and real-world applications.The proliferation of interconnected devices across various domains promises to deliver intelligent and advanced services.However,this rapid expansion also heightens the vulnerability of the IoT ecosystem to security threats.Consequently,innovative solutions capable of effectively mitigating risks while accommodating the unique constraints of IoT environments are urgently needed.Recently,the convergence of Blockchain technology and IoT has introduced a decentralized and robust framework for securing data and interactions,commonly referred to as the Internet of Blockchained Things(IoBT).Extensive research efforts have been devoted to adapting Blockchain technology to meet the specific requirements of IoT deployments.Within this context,consensus algorithms play a critical role in assessing the feasibility of integrating Blockchain into IoT ecosystems.The adoption of efficient and lightweight consensus mechanisms for block validation has become increasingly essential.This paper presents a comprehensive examination of lightweight,constraint-aware consensus algorithms tailored for IoBT.The study categorizes these consensus mechanisms based on their core operations,the security of the block validation process,the incorporation of AI techniques,and the specific applications they are designed to support.展开更多
Cooperative guidance is a method for achieving combat objectives through information sharing and cooperative effects,and has emerged as a significant research area in the fields of missile guidance and systematic warf...Cooperative guidance is a method for achieving combat objectives through information sharing and cooperative effects,and has emerged as a significant research area in the fields of missile guidance and systematic warfare.This study presents a systematic review and analysis of current research on cooperative guidance.First,a bibliometric analysis is conducted on 513 articles using the Scopus database and CiteSpace software to assess keyword clustering,keyword cooccurrence,and keyword burst,and to later visualize the results.Second,fundamental theories of cooperative guidance,including relative motion modeling methods,algebraic graph theory,and multi-agent consensus theory,are summarized.Subsequently,an overview of current cooperative laws and corresponding analysis methods is provided,with categorization based on the cooperative structure and convergence performance.Finally,we summarize current research developments based on five perspectives and propose a developmental framework based on five layers(cyber,physical,decision,information,and system),discussing potential future advancements in cooperative terminal guidance.This framework emphasizes five key areas of research:networked,heterogeneous,integrated,intelligent,and group cooperations,with the goal of offering trends and insights for futurework.展开更多
The research and development of new traditional Chinese medicine(TCM)drugs have progressively established a novel system founded on the integration of TCM theory,human experience,and clinical trials(termed the“Three ...The research and development of new traditional Chinese medicine(TCM)drugs have progressively established a novel system founded on the integration of TCM theory,human experience,and clinical trials(termed the“Three Combinations”).However,considering TCM's distinctive features of“syndrome differentiation and treatment”and“multicomponent formulations and complex mechanisms”,current TCM drug development faces challenges such as insufficient understanding of the material basis and the overall mechanism of action and an incomplete evidence chain system.Moreover,significant obstacles persist in gathering human experience data,evaluating clinical efficacy,and controlling the quality of active ingredients,which impede the innovation process in TCM drug development.Network pharmacology,centered on the“network targets”theory,transcends the limitations of the conventional“single target”reductionist research model.It emphasizes the comprehensive effects of disease or syndrome biological networks as targets to elucidate the overall regulatory mechanism of TCM prescriptions.This approach aligns with the holistic perspective of TCM,offering a novel method consistent with TCM's holistic view for investigating the complex mechanisms of TCM and developing new TCM drugs.It is internationally recognized as a“next-generation drug research model”.To advance the research of new tools,methods,and standards for TCM evaluation and to overcome fundamental,critical,and cutting-edge technical challenges in TCM regulation,this consensus aims to explore the characteristics,progress,challenges,applicable pathways,and specific applications of network pharmacology as a new theory,method,and tool in TCM drug development.The goal is to enhance the quality of TCM drug research and development and accelerate the efficiency of developing new TCM products.展开更多
Establishing Consensus with Users of Research Irradiator Devices to Facilitate Source Type Replacement Danette R.Fennesy1,Janet M.Gutiérrez1,2,Scott J.Patlovich1,Robert J.Emery1(1.The University of Texas Health S...Establishing Consensus with Users of Research Irradiator Devices to Facilitate Source Type Replacement Danette R.Fennesy1,Janet M.Gutiérrez1,2,Scott J.Patlovich1,Robert J.Emery1(1.The University of Texas Health Science Center at Houston,Environmental Health&Safety,6431 Fannin St,CYF G.102,Houston,TX,77030;2.Corresponding author)Abstract:The ability to irradiate cells,tissues,and other biological materials with high-energy photons has been an essential tool in the discovery of numerous biomedical research advancements.展开更多
Dear Editor,This letter studies output consensus problem of heterogeneous linear multiagent systems over directed graphs. A novel adaptive dynamic event-triggered controller is presented based only on the feedback com...Dear Editor,This letter studies output consensus problem of heterogeneous linear multiagent systems over directed graphs. A novel adaptive dynamic event-triggered controller is presented based only on the feedback combination of the agent's own state and neighbors' output,which can achieve exponential output consensus through intermittent communication. The controller is obtained by solving two linear matrix equations, and Zeno behavior is excluded.展开更多
Dear Editor,This letter studies the bipartite consensus tracking problem for heterogeneous multi-agent systems with actuator faults and a leader's unknown time-varying control input. To handle such a problem, the ...Dear Editor,This letter studies the bipartite consensus tracking problem for heterogeneous multi-agent systems with actuator faults and a leader's unknown time-varying control input. To handle such a problem, the continuous fault-tolerant control protocol via observer design is developed. In addition, it is strictly proved that the multi-agent system driven by the designed controllers can still achieve bipartite consensus tracking after faults occur.展开更多
This paper mainly focuses on the velocity-constrained consensus problem of discrete-time heterogeneous multi-agent systems with nonconvex constraints and arbitrarily switching topologies,where each agent has first-ord...This paper mainly focuses on the velocity-constrained consensus problem of discrete-time heterogeneous multi-agent systems with nonconvex constraints and arbitrarily switching topologies,where each agent has first-order or second-order dynamics.To solve this problem,a distributed algorithm is proposed based on a contraction operator.By employing the properties of the stochastic matrix,it is shown that all agents’position states could converge to a common point and second-order agents’velocity states could remain in corresponding nonconvex constraint sets and converge to zero as long as the joint communication topology has one directed spanning tree.Finally,the numerical simulation results are provided to verify the effectiveness of the proposed algorithms.展开更多
Traditional Internet of Things(IoT)architectures that rely on centralized servers for data management and decision-making are vulnerable to security threats and privacy leakage.To address this issue,blockchain has bee...Traditional Internet of Things(IoT)architectures that rely on centralized servers for data management and decision-making are vulnerable to security threats and privacy leakage.To address this issue,blockchain has been advocated for decentralized data management in a tamper-resistance,traceable,and transparent manner.However,a major issue that hinders the integration of blockchain and IoT lies in that,it is rather challenging for resource-constrained IoT devices to perform computation-intensive blockchain consensuses such as Proof-of-Work(PoW).Furthermore,the incentive mechanism of PoW pushes lightweight IoT nodes to aggregate their computing power to increase the possibility of successful block generation.Nevertheless,this eventually leads to the formation of computing power alliances,and significantly compromises the decentralization and security of BlockChain-aided IoT(BC-IoT)networks.To cope with these issues,we propose a lightweight consensus protocol for BC-IoT,called Proof-of-Trusted-Work(PoTW).The goal of the proposed consensus is to disincentivize the centralization of computing power and encourage the independent participation of lightweight IoT nodes in blockchain consensus.First,we put forth an on-chain reputation evaluation rule and a reputation chain for PoTW to enable the verifiability and traceability of nodes’reputations based on their contributions of computing power to the blockchain consensus,and we incorporate the multi-level block generation difficulty as a rewards for nodes to accumulate reputations.Second,we model the block generation process of PoTW and analyze the block throughput using the continuous time Markov chain.Additionally,we define and optimize the relative throughput gain to quantify and maximize the capability of PoTW that suppresses the computing power centralization(i.e.,centralization suppression).Furthermore,we investigate the impact of the computing power of the computing power alliance and the levels of block generation difficulty on the centralization suppression capability of PoTW.Finally,simulation results demonstrate the consistency of the analytical results in terms of block throughput.In particular,the results show that PoTW effectively reduces the block generation proportion of the computing power alliance compared with PoW,while simultaneously improving that of individual lightweight nodes.This indicates that PoTW is capable of suppressing the centralization of computing power to a certain degree.Moreover,as the levels of block generation difficulty in PoTW increase,its centralization suppression capability strengthens.展开更多
Intelligent blockchain is an emerging field that integrates Artificial Intelligence(AI)techniques with blockchain networks,with a particular emphasis on improving the performance of blockchain,especially in cryptocurr...Intelligent blockchain is an emerging field that integrates Artificial Intelligence(AI)techniques with blockchain networks,with a particular emphasis on improving the performance of blockchain,especially in cryptocurrencies exchanges.Meanwhile,arbitrage bots are widely deployed and increasing in intelligent blockchain.These bots exploit the characteristics of cryptocurrencies exchanges to engage in frontrunning,generating substantial profits at the expense of ordinary users.In this paper,we address this issue by proposing a more efficient asynchronous Byzantine ordered consensus protocol,which can be used to prevent arbitrage bots from changing the order of the transactions for profits in intelligent blockchain-based cryptocurrencies.Specifically,we present two signal asynchronous common subset protocols,the more optimal one with only constant time complexity.We implement both our protocol and the optimal existing solution Chronos with Go language in the same environment.The experiment results indicate that our protocols achieve a threefold improvement over Chronos in consensus latency and nearly a tenfold increase in throughput.展开更多
This paper focuses on the problem of leaderfollowing consensus for nonlinear cascaded multi-agent systems.The control strategies for these systems are transformed into successive control problem schemes for lower-orde...This paper focuses on the problem of leaderfollowing consensus for nonlinear cascaded multi-agent systems.The control strategies for these systems are transformed into successive control problem schemes for lower-order error subsystems.A distributed consensus analysis for the corresponding error systems is conducted by employing recursive methods and virtual controllers,accompanied by a series of Lyapunov functions devised throughout the iterative process,which solves the leaderfollowing consensus problem of a class of nonlinear cascaded multi-agent systems.Specific simulation examples illustrate the effectiveness of the proposed control algorithm.展开更多
The Internet of Vehicles(IoV)operates in highly dynamic and open network environments and faces serious challenges in secure and real-time authentication and consensus mechanisms.Existing methods often suffer from com...The Internet of Vehicles(IoV)operates in highly dynamic and open network environments and faces serious challenges in secure and real-time authentication and consensus mechanisms.Existing methods often suffer from complex certificate management,inefficient consensus protocols,and poor resilience in high-frequency communication,resulting in high latency,poor scalability,and unstable network performance.To address these issues,this paper proposes a secure and efficient distributed authentication scheme for IoV with reputation-driven consensus and SM9.First,this paper proposes a decentralized authentication architecture that utilizes the certificate-free feature of SM9,enabling lightweight authentication and key negotiation,thereby reducing the complexity of key management.To ensure the traceability and global consistency of authentication data,this scheme also integrates blockchain technology,applying its inherent invariance.Then,this paper introduces a reputation-driven dynamic node grouping mechanism that transparently evaluates and groups’node behavior using smart contracts to enhance network stability.Furthermore,a new RBSFT(Reputation-Based SM9 Friendly-Tolerant)consensus mechanism is proposed for the first time to enhance consensus efficiency by optimizing the PBFT algorithm.RBSFT aims to write authentication information into the blockchain ledger to achieve multi-level optimization of trust management and decision-making efficiency,thereby significantly improving the responsiveness and robustness in high-frequency IoV scenarios.Experimental results show that it excels in authentication,communication efficiency,and computational cost control,making it a feasible solution for achieving IoV security and real-time performance.展开更多
Helicobacter pylori(H.pylori),a widespread gram-negative bacterium that colonizes the stomach,causes chronic gastritis,which may progress to peptic ulcer,mucosa-associated lymphoid tissue lymphoma,and gastric cancer.H...Helicobacter pylori(H.pylori),a widespread gram-negative bacterium that colonizes the stomach,causes chronic gastritis,which may progress to peptic ulcer,mucosa-associated lymphoid tissue lymphoma,and gastric cancer.H.pylori infection affects over 50%of people in developing countries and 10%-20%in developed countries.The Kyoto consensus classifies H.pylori gastritis as an infectious disease in the International Classification of Disease 11th Revision.The Maastricht/Florence consensus recommends treatment for all infected individuals,introducing a shift in the management strategies.The prevalence of H.pylori infection is high in the Middle East,with infection rates of 40%-70%and 85%-90%being reported among children and adults,respectively.The increasing resistance to antibiotics,including macrolides and fluoroquinolones,is a major challenge in the management of H.pylori.Clarithromycin resistance,which is associated with reduced effectiveness of standard triple therapy regimens,leading to higher rates of treatment failure,impacts the eradication rates.This emphasizes the need for routine antibiotic susceptibility testing at the national level,the use of alternative therapies,including new molecular methods,and antibiotic stewardship.An online panel of experts from the Middle East,along with an international expert,developed this consensus to provide comprehensive guidelines on the diagnosis,treatment,prevention,and role of gut microbiota in H.pylori infection,with the goal of improving clinical decision-making and reducing the impact of antibiotic resistance in the region.These guidelines are intended to support healthcare professionals involved in the diagnosis and management of H.pylori,including primary care physicians,gastroenterologists,and other specialists.They may also inform future clinical research aimed at optimizing treatment strategies and addressing regional challenges.展开更多
Colon cancer(CC)laterality(right vs left)is recognized as a key determinant of clinical outcomes and treatment decisions in metastatic CC.Right-sided CC(RCC)often presents in older individuals and is associated with h...Colon cancer(CC)laterality(right vs left)is recognized as a key determinant of clinical outcomes and treatment decisions in metastatic CC.Right-sided CC(RCC)often presents in older individuals and is associated with higher rates of Kirsten rat sarcoma viral oncogene homolog and v-raf murine sarcoma viral oncogene homolog B1 mutations and deficient mismatch repair,leading to microsatellite instability-high status.Left-sided CC typically presents in younger individuals,demonstrates a more favorable prognosis,and is often Kirsten rat sarcoma viral oncogene homolog/neuroblastoma RAS viral oncogene homolog/v-raf murine sarcoma viral oncogene homolog B1 wild-type,making it more responsive to antiepidermal growth factor receptor therapy.RCC typically responds poorly to antiepidermal growth factor receptor agents;however,it may benefit from triplet chemotherapy(5-fluorouracil+leucovorin+oxaliplatin+irinotecan)with or without anti-angiogenic agents.Comprehensive molecular profiling remains challenging in low-resource settings due to limited access to advanced diagnostic tools.This review explores key epidemiological and molecular differences between RCC and left-sided CC.In the absence of complete genomic data,tumor sidedness can be a helpful guide for making treatment decisions.Here,we propose a practical algorithm that integrates basic immunohistochemistry to assess a tumor’s mismatch repair status and laterality,potentially facilitating therapy selection in resource-constrained environments.Recognizing laterality-specific trends in prognosis and treatment response can improve personalized care and outcomes for patients with CC in these environments,highlighting the essential role of cost-effective biomarker strategies.展开更多
Blockchain-based spectrum sharing with consensus is the key technology for sixth-generation mobile communication to realize dynamic spectrum management.In order to avoid the waste of computing and communication resour...Blockchain-based spectrum sharing with consensus is the key technology for sixth-generation mobile communication to realize dynamic spectrum management.In order to avoid the waste of computing and communication resources,a spectrum sharing policy-based consensus mechanism is proposed in this paper.Firstly,a spectrum sharing algorithm based on graph neural network is designed in the satelliteterrestrial spectrum sharing networks under the underlay model.It avoids high computational overhead of the traditional iterative optimization algorithm when the wireless channel condition and network topology are highly dynamic.Secondly,a consensus mechanism based on spectrum sharing strategy is designed,which converts the traditional meaningless hash problem into the graph neural network training.Miners compete for accounting rights by training a graph neutral network model that meets the spectrum sharing requirement.Finally,the consensus delay,communication and storage overhead of the proposed consensus mechanism are analyzed theoretically.The simulation results show that the proposed consensus mechanism can effectively improve spectrum efficiency with excellent scalability and generalization performance.展开更多
While Western modernization is often regarded as a dominant model of linear progress,existing theories frequently overlook the diversity of modernization paths and the underlying commonalities shared across them.The r...While Western modernization is often regarded as a dominant model of linear progress,existing theories frequently overlook the diversity of modernization paths and the underlying commonalities shared across them.The rise of alternative models,exemplified by Chinese path to modernization,underscores the potential for multiple trajectories of modernization and reveals three core elements that define these paths:building consensus on development,generating momentum for growth,and enhancing resilience to challenges.The success of Chinese path to modernization can be attributed to several key factors:the establishment of a national development consensus driven by the leadership of the Communist Party of China;the creation of development momentum through endogenous growth,optimal resource allocation,and a sustained commitment to reform and opening-up;and the strengthening of resilience via economic diversification,gradual reforms,and robust risk management strategies.In contrast,African nations present a distinct mix of traditional consensus governance and modern democratic practices,while actively engaging in development-security-governance nexus management and refining early warning and crisis management systems.These countries are exploring their own paths to modernization,informed by their unique socio-political contexts.Despite many differences in national conditions,exchanges of experiences between China and African countries-focused on development consensus,momentum,and resilience-can break the myth that“modernization equals Westernization”.Such exchanges can empower developing nations to pursue their own,independent,and context-specific routes toward modernization.展开更多
With the increasing importance of supply chain transparency,blockchain-based data has emerged as a valuable and verifiable source for analyzing procurement transaction risks.This study extends the mathematical model a...With the increasing importance of supply chain transparency,blockchain-based data has emerged as a valuable and verifiable source for analyzing procurement transaction risks.This study extends the mathematical model and proof of‘the Overall Performance Characteristics of the Supply Chain’to encompass multiple variables within blockchain data.Utilizing graph theory,the model is further developed into a single-layer neural network,which serves as the foundation for constructing two multi-layer deep learning neural network models,Feedforward Neural Network(abbreviated as FNN)and Deep Clustering Network(abbreviated as DCN).Furthermore,this study retrieves corporate data from the Chunghwa Yellow Pages online resource and Taiwan Economic Journal database(abbreviated as TEJ).These data are then virtualized using‘the Metaverse Algorithm’,and the selected virtualized blockchain variables are utilized to train a neural network model for classification.The results demonstrate that a single-layer neural network model,leveraging blockchain data and employing the Proof of Relation algorithm(abbreviated as PoR)as the activation function,effectively identifies anomalous enterprises,which constitute 7.2%of the total sample,aligning with expectations.In contrast,the multi-layer neural network models,DCN and FNN,classify an excessively large proportion of enterprises as anomalous(ranging from one-fourth to one-third),which deviates from expectations.This indicates that deep learning may still be inadequate in effectively capturing or identifying malicious corporate behaviors associated with distortions in procurement transaction data.In other words,procurement transaction blockchain data possesses intrinsic value that cannot be replaced by artificial intelligence(abbreviated as AI).展开更多
基金Project supported by the National Natural Science Foundation of China (Grant Nos 10775060 and 10805033)the Doctoral Education Foundation of National Education Committeethe Natural Science Foundation of Gansu Province
文摘This paper studies consensus problems in weighted scale-free networks of asymmetrically coupled dynamical units, where the asymmetry in a given link is deter：mined by the relative degree of the involved nodes. It shows that the asymmetry of interactions has a great effect on the consensus. Especially, when the interactions are dominant from higher- to lower-degree nodes, both the convergence speed and the robustness to communication delay are enhanced.
基金supports by the National Natural Science Foundation of China(Nos.82201135)"2015"Cultivation Program for Reserve Talents for Academic Leaders of Nanjing Stomatological School,Medical School of Nanjing University(No.0223A204).
文摘Early correction of childhood malocclusion is timely managing morphological,structural,and functional abnormalities at different dentomaxillofacial developmental stages.The selection of appropriate imaging examination and comprehensive radiological diagnosis and analysis play an important role in early correction of childhood malocclusion.This expert consensus is a collaborative effort by multidisciplinary experts in dentistry across the nation based on the current clinical evidence,aiming to provide general guidance on appropriate imaging examination selection,comprehensive and accurate imaging assessment for early orthodontic treatment patients.
文摘Distributed Federated Learning(DFL)technology enables participants to cooperatively train a shared model while preserving the privacy of their local datasets,making it a desirable solution for decentralized and privacy-preserving Web3 scenarios.However,DFL faces incentive and security challenges in the decentralized framework.To address these issues,this paper presents a Hierarchical Blockchain-enabled DFL(HBDFL)system,which provides a generic solution framework for the DFL-related applications.The proposed system consists of four major components,including a model contribution-based reward mechanism,a Proof of Elapsed Time and Accuracy(PoETA)consensus algorithm,a Distributed Reputation-based Verification Mechanism(DRTM)and an Accuracy-Dependent Throughput Management(ADTM)mechanism.The model contribution-based rewarding mechanism incentivizes network nodes to train models with their local datasets,while the PoETA consensus algorithm optimizes the tradeoff between the shared model accuracy and system throughput.The DRTM improves the system efficiency in consensus,and the ADTM mechanism guarantees that the throughput performance remains within a predefined range while improving the shared model accuracy.The performance of the proposed HBDFL system is evaluated by numerical simulations,with the results showing that the system improves the accuracy of the shared model while maintaining high throughput and ensuring security.
文摘The Internet of Things(IoT)has gained substantial attention in both academic research and real-world applications.The proliferation of interconnected devices across various domains promises to deliver intelligent and advanced services.However,this rapid expansion also heightens the vulnerability of the IoT ecosystem to security threats.Consequently,innovative solutions capable of effectively mitigating risks while accommodating the unique constraints of IoT environments are urgently needed.Recently,the convergence of Blockchain technology and IoT has introduced a decentralized and robust framework for securing data and interactions,commonly referred to as the Internet of Blockchained Things(IoBT).Extensive research efforts have been devoted to adapting Blockchain technology to meet the specific requirements of IoT deployments.Within this context,consensus algorithms play a critical role in assessing the feasibility of integrating Blockchain into IoT ecosystems.The adoption of efficient and lightweight consensus mechanisms for block validation has become increasingly essential.This paper presents a comprehensive examination of lightweight,constraint-aware consensus algorithms tailored for IoBT.The study categorizes these consensus mechanisms based on their core operations,the security of the block validation process,the incorporation of AI techniques,and the specific applications they are designed to support.
基金supported by the National Natural Science Foundation of China(No.62173274)the National Key R&D Program of China(No.2019YFA0405300)+4 种基金the Natural Science Foundation of Hunan Province of China(Nos.2021JJ10045 and 2025JJ60072)the Open Research Subject of State Key Laboratory of Intelligent Game(No.ZBKF-24-01)the Postdoctoral Fellowship Program of CPSF(No.GZB20240989)the China Postdoctoral Science Foundation(No.2024M754304)the Aeronautical Science Foundation of China(No.2023Z005030001).
文摘Cooperative guidance is a method for achieving combat objectives through information sharing and cooperative effects,and has emerged as a significant research area in the fields of missile guidance and systematic warfare.This study presents a systematic review and analysis of current research on cooperative guidance.First,a bibliometric analysis is conducted on 513 articles using the Scopus database and CiteSpace software to assess keyword clustering,keyword cooccurrence,and keyword burst,and to later visualize the results.Second,fundamental theories of cooperative guidance,including relative motion modeling methods,algebraic graph theory,and multi-agent consensus theory,are summarized.Subsequently,an overview of current cooperative laws and corresponding analysis methods is provided,with categorization based on the cooperative structure and convergence performance.Finally,we summarize current research developments based on five perspectives and propose a developmental framework based on five layers(cyber,physical,decision,information,and system),discussing potential future advancements in cooperative terminal guidance.This framework emphasizes five key areas of research:networked,heterogeneous,integrated,intelligent,and group cooperations,with the goal of offering trends and insights for futurework.
基金supported by the National Medical Products Administration Commissioned Research Project (No.20211440216)the National Administration of Traditional Chinese Medicine Science and Technology Project (No.GZY-KJS-2024-03)+3 种基金the State Key Laboratory of Drug Regulatory Science Project (No.2023SKLDRS0104)the Basic Research Program Natural Science Fund-Frontier Leading Technology Basic Research Special Project of Jiangsu Province (No.BK20232014)the Programs Foundation for Leading Talents in National Administration of Traditional Chinese Medicine of China“Qihuang scholars”Projectthe Tianjin Administration for Market Regulation Science and Technology Key Projects (No.2022-W35)。
文摘The research and development of new traditional Chinese medicine(TCM)drugs have progressively established a novel system founded on the integration of TCM theory,human experience,and clinical trials(termed the“Three Combinations”).However,considering TCM's distinctive features of“syndrome differentiation and treatment”and“multicomponent formulations and complex mechanisms”,current TCM drug development faces challenges such as insufficient understanding of the material basis and the overall mechanism of action and an incomplete evidence chain system.Moreover,significant obstacles persist in gathering human experience data,evaluating clinical efficacy,and controlling the quality of active ingredients,which impede the innovation process in TCM drug development.Network pharmacology,centered on the“network targets”theory,transcends the limitations of the conventional“single target”reductionist research model.It emphasizes the comprehensive effects of disease or syndrome biological networks as targets to elucidate the overall regulatory mechanism of TCM prescriptions.This approach aligns with the holistic perspective of TCM,offering a novel method consistent with TCM's holistic view for investigating the complex mechanisms of TCM and developing new TCM drugs.It is internationally recognized as a“next-generation drug research model”.To advance the research of new tools,methods,and standards for TCM evaluation and to overcome fundamental,critical,and cutting-edge technical challenges in TCM regulation,this consensus aims to explore the characteristics,progress,challenges,applicable pathways,and specific applications of network pharmacology as a new theory,method,and tool in TCM drug development.The goal is to enhance the quality of TCM drug research and development and accelerate the efficiency of developing new TCM products.
文摘Establishing Consensus with Users of Research Irradiator Devices to Facilitate Source Type Replacement Danette R.Fennesy1,Janet M.Gutiérrez1,2,Scott J.Patlovich1,Robert J.Emery1(1.The University of Texas Health Science Center at Houston,Environmental Health&Safety,6431 Fannin St,CYF G.102,Houston,TX,77030;2.Corresponding author)Abstract:The ability to irradiate cells,tissues,and other biological materials with high-energy photons has been an essential tool in the discovery of numerous biomedical research advancements.
基金supported by the National Science and Technology Innovation 2030-Major Program(2022ZD 0115403)the National Natural Science Foundation of China(61991414)+1 种基金Chongqing Natural Science Foundation(CSTB2023NSCQJQX0018)Beijing Natural Science Foundation(L221005)
文摘Dear Editor,This letter studies output consensus problem of heterogeneous linear multiagent systems over directed graphs. A novel adaptive dynamic event-triggered controller is presented based only on the feedback combination of the agent's own state and neighbors' output,which can achieve exponential output consensus through intermittent communication. The controller is obtained by solving two linear matrix equations, and Zeno behavior is excluded.
基金supported by the National Natural Science Foundation of China(62325304,U22B2046,62073079,62376029)the Jiangsu Provincial Scientific Research Center of Applied Mathematics(BK20233002)the China Postdoctoral Science Foundation(2023M730255,2024T171123)
文摘Dear Editor,This letter studies the bipartite consensus tracking problem for heterogeneous multi-agent systems with actuator faults and a leader's unknown time-varying control input. To handle such a problem, the continuous fault-tolerant control protocol via observer design is developed. In addition, it is strictly proved that the multi-agent system driven by the designed controllers can still achieve bipartite consensus tracking after faults occur.
基金2024 Jiangsu Province Youth Science and Technology Talent Support Project2024 Yancheng Key Research and Development Plan(Social Development)projects,“Research and Application of Multi Agent Offline Distributed Trust Perception Virtual Wireless Sensor Network Algorithm”and“Research and Application of a New Type of Fishery Ship Safety Production Monitoring Equipment”。
文摘This paper mainly focuses on the velocity-constrained consensus problem of discrete-time heterogeneous multi-agent systems with nonconvex constraints and arbitrarily switching topologies,where each agent has first-order or second-order dynamics.To solve this problem,a distributed algorithm is proposed based on a contraction operator.By employing the properties of the stochastic matrix,it is shown that all agents’position states could converge to a common point and second-order agents’velocity states could remain in corresponding nonconvex constraint sets and converge to zero as long as the joint communication topology has one directed spanning tree.Finally,the numerical simulation results are provided to verify the effectiveness of the proposed algorithms.
基金supported in part by National Key R&D Program of China(Grant No.2021YFB1714100)in part by the National Natural Science Foundation of China(NSFC)under Grant 62371239+5 种基金in part by the the Program of Science and Technology Cooperation of Nanjing with International/Hong Kong,Macao and Taiwan(Grant No.202401019)in part by the Guangdong Basic and Applied Basic Research Foundation(Grant No.2024A1515012407)in part by the the Research Center for FinTech and Digital-Intelligent Management at Shenzhen University,in part by the National Natural Science Foundation of China under Grant 62271192in part by the Equipment Pre-Research Joint Research Program of Ministry of Education under Grant 8091B032129in part by the Major Science and Technology Projects of Longmen Laboratory under Grant 231100220300 and 231100220200in part by the Central Plains Leading Talent in Scientific and Technological Innovation Program under Grant 244200510048.
文摘Traditional Internet of Things(IoT)architectures that rely on centralized servers for data management and decision-making are vulnerable to security threats and privacy leakage.To address this issue,blockchain has been advocated for decentralized data management in a tamper-resistance,traceable,and transparent manner.However,a major issue that hinders the integration of blockchain and IoT lies in that,it is rather challenging for resource-constrained IoT devices to perform computation-intensive blockchain consensuses such as Proof-of-Work(PoW).Furthermore,the incentive mechanism of PoW pushes lightweight IoT nodes to aggregate their computing power to increase the possibility of successful block generation.Nevertheless,this eventually leads to the formation of computing power alliances,and significantly compromises the decentralization and security of BlockChain-aided IoT(BC-IoT)networks.To cope with these issues,we propose a lightweight consensus protocol for BC-IoT,called Proof-of-Trusted-Work(PoTW).The goal of the proposed consensus is to disincentivize the centralization of computing power and encourage the independent participation of lightweight IoT nodes in blockchain consensus.First,we put forth an on-chain reputation evaluation rule and a reputation chain for PoTW to enable the verifiability and traceability of nodes’reputations based on their contributions of computing power to the blockchain consensus,and we incorporate the multi-level block generation difficulty as a rewards for nodes to accumulate reputations.Second,we model the block generation process of PoTW and analyze the block throughput using the continuous time Markov chain.Additionally,we define and optimize the relative throughput gain to quantify and maximize the capability of PoTW that suppresses the computing power centralization(i.e.,centralization suppression).Furthermore,we investigate the impact of the computing power of the computing power alliance and the levels of block generation difficulty on the centralization suppression capability of PoTW.Finally,simulation results demonstrate the consistency of the analytical results in terms of block throughput.In particular,the results show that PoTW effectively reduces the block generation proportion of the computing power alliance compared with PoW,while simultaneously improving that of individual lightweight nodes.This indicates that PoTW is capable of suppressing the centralization of computing power to a certain degree.Moreover,as the levels of block generation difficulty in PoTW increase,its centralization suppression capability strengthens.
基金supported by the National Key R&D Program of China under Grant(2022YFB2702702)in part by the National Natural Science Foundation of China under Grants(62372020,72031001)+1 种基金in part by the Beijing Natural Science Foundation under Grants(L222050)in part by the Fundamental Research Funds for the Central Universities under Grant(YWF-23-L-1032).
文摘Intelligent blockchain is an emerging field that integrates Artificial Intelligence(AI)techniques with blockchain networks,with a particular emphasis on improving the performance of blockchain,especially in cryptocurrencies exchanges.Meanwhile,arbitrage bots are widely deployed and increasing in intelligent blockchain.These bots exploit the characteristics of cryptocurrencies exchanges to engage in frontrunning,generating substantial profits at the expense of ordinary users.In this paper,we address this issue by proposing a more efficient asynchronous Byzantine ordered consensus protocol,which can be used to prevent arbitrage bots from changing the order of the transactions for profits in intelligent blockchain-based cryptocurrencies.Specifically,we present two signal asynchronous common subset protocols,the more optimal one with only constant time complexity.We implement both our protocol and the optimal existing solution Chronos with Go language in the same environment.The experiment results indicate that our protocols achieve a threefold improvement over Chronos in consensus latency and nearly a tenfold increase in throughput.
基金National Natural Science Foundation of China(No.12071370)。
文摘This paper focuses on the problem of leaderfollowing consensus for nonlinear cascaded multi-agent systems.The control strategies for these systems are transformed into successive control problem schemes for lower-order error subsystems.A distributed consensus analysis for the corresponding error systems is conducted by employing recursive methods and virtual controllers,accompanied by a series of Lyapunov functions devised throughout the iterative process,which solves the leaderfollowing consensus problem of a class of nonlinear cascaded multi-agent systems.Specific simulation examples illustrate the effectiveness of the proposed control algorithm.
基金supported by the National Natural Science Foundation of China(Grant No.61762071,Grant No.61163025).
文摘The Internet of Vehicles(IoV)operates in highly dynamic and open network environments and faces serious challenges in secure and real-time authentication and consensus mechanisms.Existing methods often suffer from complex certificate management,inefficient consensus protocols,and poor resilience in high-frequency communication,resulting in high latency,poor scalability,and unstable network performance.To address these issues,this paper proposes a secure and efficient distributed authentication scheme for IoV with reputation-driven consensus and SM9.First,this paper proposes a decentralized authentication architecture that utilizes the certificate-free feature of SM9,enabling lightweight authentication and key negotiation,thereby reducing the complexity of key management.To ensure the traceability and global consistency of authentication data,this scheme also integrates blockchain technology,applying its inherent invariance.Then,this paper introduces a reputation-driven dynamic node grouping mechanism that transparently evaluates and groups’node behavior using smart contracts to enhance network stability.Furthermore,a new RBSFT(Reputation-Based SM9 Friendly-Tolerant)consensus mechanism is proposed for the first time to enhance consensus efficiency by optimizing the PBFT algorithm.RBSFT aims to write authentication information into the blockchain ledger to achieve multi-level optimization of trust management and decision-making efficiency,thereby significantly improving the responsiveness and robustness in high-frequency IoV scenarios.Experimental results show that it excels in authentication,communication efficiency,and computational cost control,making it a feasible solution for achieving IoV security and real-time performance.
文摘Helicobacter pylori(H.pylori),a widespread gram-negative bacterium that colonizes the stomach,causes chronic gastritis,which may progress to peptic ulcer,mucosa-associated lymphoid tissue lymphoma,and gastric cancer.H.pylori infection affects over 50%of people in developing countries and 10%-20%in developed countries.The Kyoto consensus classifies H.pylori gastritis as an infectious disease in the International Classification of Disease 11th Revision.The Maastricht/Florence consensus recommends treatment for all infected individuals,introducing a shift in the management strategies.The prevalence of H.pylori infection is high in the Middle East,with infection rates of 40%-70%and 85%-90%being reported among children and adults,respectively.The increasing resistance to antibiotics,including macrolides and fluoroquinolones,is a major challenge in the management of H.pylori.Clarithromycin resistance,which is associated with reduced effectiveness of standard triple therapy regimens,leading to higher rates of treatment failure,impacts the eradication rates.This emphasizes the need for routine antibiotic susceptibility testing at the national level,the use of alternative therapies,including new molecular methods,and antibiotic stewardship.An online panel of experts from the Middle East,along with an international expert,developed this consensus to provide comprehensive guidelines on the diagnosis,treatment,prevention,and role of gut microbiota in H.pylori infection,with the goal of improving clinical decision-making and reducing the impact of antibiotic resistance in the region.These guidelines are intended to support healthcare professionals involved in the diagnosis and management of H.pylori,including primary care physicians,gastroenterologists,and other specialists.They may also inform future clinical research aimed at optimizing treatment strategies and addressing regional challenges.
文摘Colon cancer(CC)laterality(right vs left)is recognized as a key determinant of clinical outcomes and treatment decisions in metastatic CC.Right-sided CC(RCC)often presents in older individuals and is associated with higher rates of Kirsten rat sarcoma viral oncogene homolog and v-raf murine sarcoma viral oncogene homolog B1 mutations and deficient mismatch repair,leading to microsatellite instability-high status.Left-sided CC typically presents in younger individuals,demonstrates a more favorable prognosis,and is often Kirsten rat sarcoma viral oncogene homolog/neuroblastoma RAS viral oncogene homolog/v-raf murine sarcoma viral oncogene homolog B1 wild-type,making it more responsive to antiepidermal growth factor receptor therapy.RCC typically responds poorly to antiepidermal growth factor receptor agents;however,it may benefit from triplet chemotherapy(5-fluorouracil+leucovorin+oxaliplatin+irinotecan)with or without anti-angiogenic agents.Comprehensive molecular profiling remains challenging in low-resource settings due to limited access to advanced diagnostic tools.This review explores key epidemiological and molecular differences between RCC and left-sided CC.In the absence of complete genomic data,tumor sidedness can be a helpful guide for making treatment decisions.Here,we propose a practical algorithm that integrates basic immunohistochemistry to assess a tumor’s mismatch repair status and laterality,potentially facilitating therapy selection in resource-constrained environments.Recognizing laterality-specific trends in prognosis and treatment response can improve personalized care and outcomes for patients with CC in these environments,highlighting the essential role of cost-effective biomarker strategies.
基金supported in part by the National Natural Science Foundation of China under Grant 62171020.
文摘Blockchain-based spectrum sharing with consensus is the key technology for sixth-generation mobile communication to realize dynamic spectrum management.In order to avoid the waste of computing and communication resources,a spectrum sharing policy-based consensus mechanism is proposed in this paper.Firstly,a spectrum sharing algorithm based on graph neural network is designed in the satelliteterrestrial spectrum sharing networks under the underlay model.It avoids high computational overhead of the traditional iterative optimization algorithm when the wireless channel condition and network topology are highly dynamic.Secondly,a consensus mechanism based on spectrum sharing strategy is designed,which converts the traditional meaningless hash problem into the graph neural network training.Miners compete for accounting rights by training a graph neutral network model that meets the spectrum sharing requirement.Finally,the consensus delay,communication and storage overhead of the proposed consensus mechanism are analyzed theoretically.The simulation results show that the proposed consensus mechanism can effectively improve spectrum efficiency with excellent scalability and generalization performance.
基金This article forms part of the 2021 Major Bidding Project under the Special Research Program on Significant Historical Issues,supported by the Chinese Academy of History and funded by the National Social Science Foundation of China:“General History of Africa(Multi-Volume Edition)”(Grant No.LSYZD21022).
文摘While Western modernization is often regarded as a dominant model of linear progress,existing theories frequently overlook the diversity of modernization paths and the underlying commonalities shared across them.The rise of alternative models,exemplified by Chinese path to modernization,underscores the potential for multiple trajectories of modernization and reveals three core elements that define these paths:building consensus on development,generating momentum for growth,and enhancing resilience to challenges.The success of Chinese path to modernization can be attributed to several key factors:the establishment of a national development consensus driven by the leadership of the Communist Party of China;the creation of development momentum through endogenous growth,optimal resource allocation,and a sustained commitment to reform and opening-up;and the strengthening of resilience via economic diversification,gradual reforms,and robust risk management strategies.In contrast,African nations present a distinct mix of traditional consensus governance and modern democratic practices,while actively engaging in development-security-governance nexus management and refining early warning and crisis management systems.These countries are exploring their own paths to modernization,informed by their unique socio-political contexts.Despite many differences in national conditions,exchanges of experiences between China and African countries-focused on development consensus,momentum,and resilience-can break the myth that“modernization equals Westernization”.Such exchanges can empower developing nations to pursue their own,independent,and context-specific routes toward modernization.
文摘With the increasing importance of supply chain transparency,blockchain-based data has emerged as a valuable and verifiable source for analyzing procurement transaction risks.This study extends the mathematical model and proof of‘the Overall Performance Characteristics of the Supply Chain’to encompass multiple variables within blockchain data.Utilizing graph theory,the model is further developed into a single-layer neural network,which serves as the foundation for constructing two multi-layer deep learning neural network models,Feedforward Neural Network(abbreviated as FNN)and Deep Clustering Network(abbreviated as DCN).Furthermore,this study retrieves corporate data from the Chunghwa Yellow Pages online resource and Taiwan Economic Journal database(abbreviated as TEJ).These data are then virtualized using‘the Metaverse Algorithm’,and the selected virtualized blockchain variables are utilized to train a neural network model for classification.The results demonstrate that a single-layer neural network model,leveraging blockchain data and employing the Proof of Relation algorithm(abbreviated as PoR)as the activation function,effectively identifies anomalous enterprises,which constitute 7.2%of the total sample,aligning with expectations.In contrast,the multi-layer neural network models,DCN and FNN,classify an excessively large proportion of enterprises as anomalous(ranging from one-fourth to one-third),which deviates from expectations.This indicates that deep learning may still be inadequate in effectively capturing or identifying malicious corporate behaviors associated with distortions in procurement transaction data.In other words,procurement transaction blockchain data possesses intrinsic value that cannot be replaced by artificial intelligence(abbreviated as AI).
