This study,based on the theory of shifting essence and changing Qi in Inner Canon of Huangdi,deeply explores the theoretical basis,operation method of Conception Vessel Dredging Therapy and its influence on human heal...This study,based on the theory of shifting essence and changing Qi in Inner Canon of Huangdi,deeply explores the theoretical basis,operation method of Conception Vessel Dredging Therapy and its influence on human health.Through case analysis and the statistical analysis of medical records during the pandemic,it reveals the remarkable effects of this method in regulating the endocrine system,improving metabolism,and relieving physical and mental diseases.It provides a theoretical and practical basis for the application of traditional Chinese medicine anti-aging therapy in the modern health field,and helps to explore new ways to delay aging and improve physical and mental health.展开更多
Objective To explore the effect of electroacupuncture at conception vessel and governor vessel on correlative signals of inflammatory response stressinjury-repair in cerebral ischemia reperfusion rats. Methods A total...Objective To explore the effect of electroacupuncture at conception vessel and governor vessel on correlative signals of inflammatory response stressinjury-repair in cerebral ischemia reperfusion rats. Methods A total of 216 rats were included in the experiment, of which 192 rats were randomly divided into four groups, including sham operation group（group A）, model group（group B）, governor vessel group（group C）, and conception vessel and governor vessel group（group D）, 48 rats in each group. The rats in each group were further divided into six sub-groups, including 12 h group, 24 h group, 48 h group, 72 h group, 96 h group and 144 h group. MCAO operation course was simulated in group A, and the common carotid artery, internal carotid artery and external carotid artery on the right side were exposed, without insertion of suture or treatment. After completion of modeling in group B, treatment was not conducted. After completion of modeling in group C, ＂Shuǐgōu（水沟 GV 26）＂, ＂Bǎihuì（百会 GV 20）＂ and ＂Dàzhuī（大椎 GV 14）＂ of governor vessel were selected, and electroacupuncture device was connected with ＂GV 14＂ and ＂GV 20＂. After completion of modeling in group D, ＂GV 26＂, ＂GV 20＂ and ＂GV 14＂ of governor vessel, and ＂Qìhǎi（气海 CV 6）＂, ＂Guānyuán（关元 CV 4）＂ and ＂Chéngjiāng（承浆 CV 24）＂ of conception vessel were selected; electroacupuncture device was connected with ＂GV 14＂ and ＂GV 20＂, ＂CV 4＂ and ＂CV 6＂. Neurological severity score was conducted.Enzyme linked immunosorbent assay（ELISA） was applied to determine the concentration of peripheral serum adrenocorticotropic hormone（ACTH） of rats, and immunohistochemical method was adopted to detect the expression levels of tumor necrosis factor α（TNF-α） and transforming growth factor β1（TGF-β1） in brain tissue of rats. The other 24 rats were also randomly divided into four groups mentioned above, 6 rats in each group, to detect cerebral ischemie volume. Results Compared with group B, the ischemia volume in brain tissue at 144 h after cerebral ischemia reperfusion decreased significantly in group C and group D（P〈0.05）, and the ischemia volume in group D was less than that in group C（P〈0.05）. The neurological impairment scores of group C and group D at all time points were lower than those of group B, and the differences were statistically significant（all P〈0.05）. The scores of group D at all time points were lower than those of group C, and the differences since 24 h were statistically significant（all P〈0.05）. Compared with group B, the excessive expression of ACTH was suppressed dynamically and generally in group C and group D（P〈0.05）; the expression level of TNF-α was down-regulated and TGF-β1 was up-regulated as well in group C and group D（P〈0.05）. The effect in group D was superior to that in group C. Conclusion Electroacupuncture at conception vessel and governor vessel can protect brain through the intervention of the expression of correlative signals of inflammatory response stress-injury-repair of cerebral ischemia reperfusion.展开更多
In modern Chinese style garden, the designer could express the emotions in garden creation to produce artistic conception with landscape plants, which could make the sightseers desire to integrate with the nature and ...In modern Chinese style garden, the designer could express the emotions in garden creation to produce artistic conception with landscape plants, which could make the sightseers desire to integrate with the nature and led to sympathizing with the concept, thereby motivating and arousing people＇s emotion to return to and close to nature. Through the 6 specific characteristics of ＂shape, color, aroma, shadow, sound and art＂ of landscape plants, some ways to build artistic conception in Chinese style garden were introduced in this study to provide references for the creation of artistic conception creation through senses in the future landscaping design.展开更多
This study explored the origin and development of modern garden city,by integrating concepts of world modern garden city and characteristics of Chengdu cultures,analyzed the application of its aesthetic value and the ...This study explored the origin and development of modern garden city,by integrating concepts of world modern garden city and characteristics of Chengdu cultures,analyzed the application of its aesthetic value and the design of its artistic conception.It was found that Chengdu City had high aesthetic value such as a large area of green spaces and unique recreational cultures,as well as a great potential of unifying idyllic images and natural cultures.To design Chengdu into a world modern garden city,the planning of its urban green space system should be taken as the foundation,"one group and three districts" as the construction system,urban folk cultures,logistics and traffic,information and other such networks as the support to achieve the "beauty of nature,social equity and urban-rural integration".展开更多
To better inherit traditional culture in creating artistic conception in modern gardens and develop the style and function of garden artistic conception,this study summarized various creation techniques of traditional...To better inherit traditional culture in creating artistic conception in modern gardens and develop the style and function of garden artistic conception,this study summarized various creation techniques of traditional garden artistic conceptions from the perspective of design thought and conception of classical Chinese gardens.It was put forward that the creation of artistic conception in modern gardens should be human-centered in a great culture context;and meanwhile,aesthetic habits of modern people should be respected and traditional thoughts should be developed to enrich the connotation of garden artistic conception design.展开更多
Elementary knowledge of classical Chinese gardens was introduced,its history was studied in 3 stages:initial phase,development phase and prosperous phase,component system of classical Chinese gardens was introduced fr...Elementary knowledge of classical Chinese gardens was introduced,its history was studied in 3 stages:initial phase,development phase and prosperous phase,component system of classical Chinese gardens was introduced from different perspectives,cultural background and specific demonstrations of its artistic conceptions were expounded as key points,and it was proposed that its artistic conceptions were actually reverence and respect for the nature,and also expressions of various philosophical doctrines and religious cultures.On this basis,construction techniques and connotations of artistic conception were researched as well as its components and expression ways.It was proposed that construction elements of artistic conceptions included buildings,hill stones,water and plants;image-building in the landscaping should be stressed,and artistic conception integrated into key points to bring out the theme,garden scenes and paintings combined.This study aimed at providing references for relevant researches through introducing classical Chinese gardens and their artistic conceptions.展开更多
In the field of second language acquisition, an increasing amount of research has been conducted on learner＇s beliefs. Few empirical studies, however, have been focused on students＇ conceptions of learning English ...In the field of second language acquisition, an increasing amount of research has been conducted on learner＇s beliefs. Few empirical studies, however, have been focused on students＇ conceptions of learning English （COLE）. This study aims to assess conceptions of learning particularly in the domain of English. Data were collected through the COLE questionnaire among 284 college students in China. Seven factors of COLE are identified, such as ＂memorizing＂, ＂testing＂, ＂drill and practice＂, ＂increasing knowledge＂, ＂understanding＂, ＂application＂, and ＂seeing in a new way＂. These findings also provide some pedagogical implications for English language instructors and researchers.展开更多
Effective teaching has always been a goal pursued by teachers as a part of education both from the western and eastern society,for it to some extend is considered an effective way to improve society.In this essay,both...Effective teaching has always been a goal pursued by teachers as a part of education both from the western and eastern society,for it to some extend is considered an effective way to improve society.In this essay,both Chinese and western conceptions of teaching and learning will be discussed.In doing so,their differences and similarities can be seen clearly,which will help the cross-cultural educators to understand their teaching environment and learning styles.展开更多
Any everyday subject may trigger individual conceptions either scientifically correct or naively shaped (misconceptions, alternative conceptions). For any educator, knowledge about a pupil’s individual perception may...Any everyday subject may trigger individual conceptions either scientifically correct or naively shaped (misconceptions, alternative conceptions). For any educator, knowledge about a pupil’s individual perception may strongly support teaching success. Within this context, we see the use of drinking water as daily behavior loaded with conceptions. We monitored the perceptions of two different samples, of high achieving 10th graders and of undergraduates in Biology. All participants responded to three closed and three open questions requesting individual statements about drinking water. All open questions were categorized via qualitative content analysis mainly revealing the perception of drinking water as a clean product, precisely controlled and drinkable with no need for worry. In general, some alternative conceptions did not seem differ in both samples over the time of about five years: For instance, many see our drinking water as purified in sewage plants. However, differences between individuals exist: For example, whether water is consumed as tap or bottled water. Here, some name water hardness as the reason to not drink tap water, because they think it is harmful (although the very same participants prefer bottled mineral water). Other conceptions seem to change over time, such as the estimation about the remaining time until our drinking water might be used up, or familiarity with the term “virtual water”. Summing up, we did find a positive attitude towards national drinking water policy, although major knowledge gaps need its mentioning. The relevance of these results and strategies for public and school teaching are discussed.展开更多
Mesenchymal stem cell transplantation is a novel means of treating cerebral ischemia/reper- fusion, and can promote angiogenesis and neurological functional recovery. Acupuncture at Conception and Governor vessels als...Mesenchymal stem cell transplantation is a novel means of treating cerebral ischemia/reper- fusion, and can promote angiogenesis and neurological functional recovery. Acupuncture at Conception and Governor vessels also has positive effects as a treatment for cerebral ischemia/ reperfusion. Therefore, we hypothesized that electro-acupuncture at Conception and Governor vessels plus mesenchymal stem cell transplantation may have better therapeutic effects on the promotion of angiogenesis and recovery of neurological function than either treatment alone. In the present study, human umbilical cord blood-derived mesenchymal stem cells were isolated, cultured, identified and intracranially transplanted into the striatum and subcortex of rats at 24 hours following cerebral ischemia/reperfusion. Subsequently, rats were electro-acupunctured at Conception and Governor vessels at 24 hours after transplantation. Modified neurological severity scores and immunohistochemistry findings revealed that the combined interventions of electro-acupuncture and mesenchymal stem cell transplantation clearly improved neurological impairment and up-regulated vascular endothelial growth factor expression around the isch- emic focus. The combined intervention provided a better outcome than mesenchymal stem cell transplantation alone. These findings demonstrate that electro-acupuncture at Conception and Governor vessels and mesenchymal stem cell transplantation have synergetic effects on promot- ing neurological function recovery and angiogenesis in rats after cerebral ischemia/reperfusion.展开更多
OBJECTIVE: To investigate the combinatorial effects of conception and governor vessel electroacupuncture(EA) and human umbilical cord blood-derived mesenchymal stem cells(HUCB-MSCs) on pathomorphologic lesion and cell...OBJECTIVE: To investigate the combinatorial effects of conception and governor vessel electroacupuncture(EA) and human umbilical cord blood-derived mesenchymal stem cells(HUCB-MSCs) on pathomorphologic lesion and cellular apoptosis in rats with cerebral ischemia/reperfusion. METHODS: With the HUCB-MSCs isolated, cultured and identified and the models of cerebral ischemia-reperfusion established, the HUCB-MSCs of passage three were intracranially transplanted and the EA at conception and governor vessels was applied. The pathomorphologic lesion by hematoxylin-eosin staining and the cellular apoptosis by terminal deoxynucleotidyl transferase-mediated nick-end labeling method around the ischemic focus were observed. RESULTS: The cultured adherent HUCB-MSCs exhibited a spindle shape and expressed MSC-specific markers, with the cell purity and proliferation rate significantly increasing after the primary passage. HE staining showed that there were no pathological changes observed in the sham surgery group. However, in the PBS transplantation group, degeneration and necrosis of a great number of nerve cells were seen. In both the HUCB-MSCs transplantation group and the HUCB-MSCs transplantation + EA group, reparative changes of the pathomorphism of the tissue were found. Both combination treatment and simple MSCs treatment were able to improve the pathomorphorlogic lesion following cerebral ischemia and reduce the abnormal TUNEL-positive numbers, with former better than latter. CONCLUSION: HUCB-MSCs improve pathological lesions and inhibit the cellular apoptosis around the cerebral ischemic area. EA at conception and governor vessels also improve pathological lesion and inhibit the cellular apoptosis in rats treated with HUCB-MSCs transplantation, which effects were superior to that of simple HUCB-MSCs transplantation.展开更多
Approximately 30% of pregnancies after implantation end up in spontaneous abortions, and 50% of them are caused by chromosomal abnormalities. However, the spectrum of genomic copy number variants （CNVs） in products ...Approximately 30% of pregnancies after implantation end up in spontaneous abortions, and 50% of them are caused by chromosomal abnormalities. However, the spectrum of genomic copy number variants （CNVs） in products of conception （POC） and the underlying gene- dosage-sensitive mechanisms causing spontaneous abortions remain largely unknown. In this study, array comparative genornic hybridiza- tion （aCGH） analysis was performed as a salvage procedure for 128 POC culture failure （POC-CF） samples and as a supplemental procedure for 106 POC normal karyotype （POC-NK） samples. Chromosomal abnormalities were detected in 10% of POC-CF and pathogenic CNVs were detected in 3.9% of POC-CF and 5.7% of POC-NK samples. Compiled results from this study and relevant case series through a literature review demonstrated an abnormality detection rate （ADR） of 35% for chromosomal abnormalities in POC-CF samples, 3.7% for pathogenic CNVs in POC-CF samples, and 4.6% for pathogenic CNVs in POC-NK samples. Ingenuity Pathway Analysis （IPA） was performed on the genes from pathogenic CNVs found in POC samples. The denoted primary gene networks suggested that apoptosis and cell proliferation pathways are involved in miscarriage. In summary, a similar spectrum of cytogenomic abnormalities was observed in POC culture success and POC-CF samples. A threshold effect correlating the number of dosage-sensitive genes in a chromosome with the observed frequency of autosomai trisomy is proposed. A rationalized approach using firstly fluorescence in situ hybridization （FISH） testing with probes of chromosomes X/Y/ 18, 13/21, and 15/16/22 for common aneuploidies and polyploidies and secondly aCGH for other cytogenomic abnormalities is recommended for POC-CF samples.展开更多
Purpose:In studies of the research process,the association between how researchers conceptualize research and their strategic research agendas has been largely overlooked.This study aims to address this gap.Design/met...Purpose:In studies of the research process,the association between how researchers conceptualize research and their strategic research agendas has been largely overlooked.This study aims to address this gap.Design/methodology/approach:This study analyzes this relationship using a dataset of more than 8,500 researchers across all scientific fields and the globe.It studies the associations between the dimensions of two inventories:the Conceptions of Research Inventory(CoRI)and the Multi-Dimensional Research Agenda Inventory—Revised(MDRAI-R).Findings:The findings show a relatively strong association between researchers’conceptions of research and their research agendas.While all conceptions of research are positively related to scientific ambition,the findings are mixed regarding how the dimensions of the two inventories relate to one another,which is significant for those seeking to understand the knowledge production process better.Research limitations:The study relies on self-reported data,which always carries a risk of response bias.Practical implications:The findings provide a greater understanding of the inner workings of knowledge processes and indicate that the two inventories,whether used individually or in combination,may provide complementary analytical perspectives to research performance indicators.They may thus offer important insights for managers of research environments regarding how to assess the research culture,beliefs,and conceptualizations of individual researchers and research teams when designing strategies to promote specific institutional research focuses and strategies.Originality/value:To the best of the authors’knowledge,this is the first study to associate research agendas and conceptions of research.It is based on a large sample of researchers working worldwide and in all fields of knowledge,which ensures that the findings have a reasonable degree of generalizability to the global population of researchers.展开更多
When the stagnation temperature of a perfect gas increases, the specific heats and their ratio do not remain constant any more and start to vary with this temperature. The gas remains perfect, its state equation remai...When the stagnation temperature of a perfect gas increases, the specific heats and their ratio do not remain constant any more and start to vary with this temperature. The gas remains perfect, its state equation remains always valid, except it will name in more calorically imperfect gas or gas at High Temperature. The goal of this research is to trace the profiles of the supersonic plug nozzle when this stagnation temperature is taken into account, lower than the threshold of dissociation of the molecules, by using the new formula of the Prandtl Meyer function, and to have for each exit Mach number, several nozzles shapes by changing the value of this temperature. A study on the error given by the PG （perfect gas） model compared to our model at high temperature is presented. The comparison is made with the case of a calorically perfect gas aiming to give a limit of application of this model. The application is for the air.展开更多
Dairy heifers only start to produce a return on investment at first calving. The length of the non-productive rearing period is largely governed by farmer decisions on plane of nutrition and reproduction management. P...Dairy heifers only start to produce a return on investment at first calving. The length of the non-productive rearing period is largely governed by farmer decisions on plane of nutrition and reproduction management. Primary data were collected from 101 dairy farms and a cost analysis workbook developed to calculate individual inputs in each of three periods to determine which management decisions and farm factors have the greatest influence on the total costs associated with rearing. This paper covers weaning until conception. Heifers were weaned at 62 d (range 42 - 112 d) and conceived by 509 d (range 365 - 700 d) giving an average weaning to conception period of 447 ± 60 d (range 253 to 630 d). The mean daily cost of rearing during this period was ￡1.65 (range ￡0.75 to ￡2.97 on different farms) giving a mean total cost of ￡745.94 per heifer (range ￡295.32 to ￡1745.85). This large variation was mostly due to the duration, which was mainly determined by age at first breeding (mean 476 days, range 365 - 700 d). The main contributors to total costs were feed (35.6%), labour (24.7%) and bedding (8.9%). The variables most strongly associated with the total costs were age at conception, calving pattern and breed. A multivariable model predicted an increase in mean cost of ￡2.26 for each extra day in age at conception. The total cost was highest in herds with all year round calving, intermediate in multi-block and lowest in spring and autumn calving herds, with Friesian x and Jersey herds having the lowest cost of rearing.展开更多
Objective:Objective:To observe the therapeutic effect of cross-shaped moxibustion on the conception vessel and belt vessel for dysmenorrhea due to qi and blood deficiency.Methods:Taking Shenque(神阙CV8)as the center,u...Objective:Objective:To observe the therapeutic effect of cross-shaped moxibustion on the conception vessel and belt vessel for dysmenorrhea due to qi and blood deficiency.Methods:Taking Shenque(神阙CV8)as the center,up to Zhongwan(中脘CV12),down to Zhongji(中极CV3),and both sides to Daimai(带脉GB26),the above mentioned were treated area.The patient’s umbilicus was filled with the herbal powder for moxibustion and the powder was also scattered in a straight line along the treated area.The two sheets of mulberry paper were put in a cross way on the herbal powder for moxibustion,and the cross-shaped moxibustion box was put on the paper.The ginger paste was put into the box to a height of 3 cm and pressed tightly with a tongue depressor,the margin of the ginger paste should be clinged to the moxibustion box.The moxa cones were put end to end in the groove on the median of the ginger paste and ignited orderly.When the cones were burnt completely,the new cones were used and ignited.Three cones were adopted in succession in each treatment.The treatment was given once a week,and three treatments as one course,the therapeutic effect was evaluated after two courses of treatment.Results:There were 16 cases cured,5 cases effective and 2 cases non-effective in all.The total effective rate was 91.3%.Conclusion:Coss-shaped moxibustion on the conception vessel and belt vessel has sound effect for dysmenorrhea due to qi and blood deficiency.展开更多
[Objective] Taking the knowledge of tea-science field as research object,an extraction method for the taxonomic relation of ontology conception was proposed in the paper.[Method] Through improving the rule based on la...[Objective] Taking the knowledge of tea-science field as research object,an extraction method for the taxonomic relation of ontology conception was proposed in the paper.[Method] Through improving the rule based on language mode,generalized suffix tree was constructed for the concept set of tea-science field,forming hierarchical structure and taxonomic relation among conceptions.[Result and Conclusion] Moreover,corresponding prototype system was developed based on above method,and test result indicating that the method was effective.展开更多
Chinese classical poetry has long been known for its unique artistic conception of mixture of sentiments andscenery, the conception beyond image and the refinement out of rhyme. From the perspective of receptionaesthe...Chinese classical poetry has long been known for its unique artistic conception of mixture of sentiments andscenery, the conception beyond image and the refinement out of rhyme. From the perspective of receptionaesthetics theory, this paper analyzes translation strategies of the classical poetry, probes into the problems thatretaining “indeterminacy” and satisfying the readers “horizon of expectations” when translate Chinese classicalpoetry. It is necessary to keep enough aesthetic space, and to give full play to the translator’s aesthetic creativitywhen translate Chinese classical poetry, so as to reproduce the artistic conception of Chinese classical poetry.展开更多
The theme of the Conception of the Virgin Mary fascinated 16th-century Mannerist painters, as manifested in Giorgio Vasari＇s many drawings and paintings and also the numerous replicas in drawings, paintings, and engr...The theme of the Conception of the Virgin Mary fascinated 16th-century Mannerist painters, as manifested in Giorgio Vasari＇s many drawings and paintings and also the numerous replicas in drawings, paintings, and engravings made after his paintings by his contemporary artists. This essay focuses on Vasari＇s complex iconography of The Conception of Our Lady of 1540 at SS. Apostoli in Florence, Italy. In his documentation of the painting, Vasari never referred to or entitled the painting as an Allegory of the Immaculate Conception or Immaculate Conception but coined it as The Conception of Our Lady （Concezione di Nostra Donna） as it will be referred in this essay. Vasari＇s complex iconography derived from the writings of the A retine canon Giovanni Pollastra. The Virgin Mary is depicted as a victorious symbol of grace and salvation, triumphing over evil. Rejoicing angels surround her with scrolls containing Latin inscriptions, QUOS EVE CULPA DAAVIT/MARIAE GRATIAE SOLVIT, ECCE AGNIU[S] and UNIUS ONNOSTAA. These joyful words allude to the restoration of the fate of Adam and Eve after eating the forbidden fruit from the Tree of Knowledge in Paradise. A sinuous serpent coils around the fig tree, while tied-up Old Testament and New Testaments wait for forgiveness and salvation. Three considerations are addressed in this essay： （1） discussion of Vasari＇s recorded commissions; （2） stylistic observations and influences; and （3） interpretation of the imagery, that is, some observations on the symbolism of the painting.展开更多
After the September 11th events and especially after the follow-updevelopment of the US-Russian relationship,many Americangovernment officials in the Bush team stated time and again in
基金Supported by Natural Science Foundation of China,Taoist Qi Healing the World Project(Project No.:71971359).
文摘This study,based on the theory of shifting essence and changing Qi in Inner Canon of Huangdi,deeply explores the theoretical basis,operation method of Conception Vessel Dredging Therapy and its influence on human health.Through case analysis and the statistical analysis of medical records during the pandemic,it reveals the remarkable effects of this method in regulating the endocrine system,improving metabolism,and relieving physical and mental diseases.It provides a theoretical and practical basis for the application of traditional Chinese medicine anti-aging therapy in the modern health field,and helps to explore new ways to delay aging and improve physical and mental health.
基金Supported by Shenzhen Municipal Scientific and Technological Innovation Committee:JCYJ 20140408152909270Project of Shenzhen Municipal Key Laboratory of Technical Research and Development Fund Conditions and Platform Construction Plan:CXB 201111250113A
文摘Objective To explore the effect of electroacupuncture at conception vessel and governor vessel on correlative signals of inflammatory response stressinjury-repair in cerebral ischemia reperfusion rats. Methods A total of 216 rats were included in the experiment, of which 192 rats were randomly divided into four groups, including sham operation group（group A）, model group（group B）, governor vessel group（group C）, and conception vessel and governor vessel group（group D）, 48 rats in each group. The rats in each group were further divided into six sub-groups, including 12 h group, 24 h group, 48 h group, 72 h group, 96 h group and 144 h group. MCAO operation course was simulated in group A, and the common carotid artery, internal carotid artery and external carotid artery on the right side were exposed, without insertion of suture or treatment. After completion of modeling in group B, treatment was not conducted. After completion of modeling in group C, ＂Shuǐgōu（水沟 GV 26）＂, ＂Bǎihuì（百会 GV 20）＂ and ＂Dàzhuī（大椎 GV 14）＂ of governor vessel were selected, and electroacupuncture device was connected with ＂GV 14＂ and ＂GV 20＂. After completion of modeling in group D, ＂GV 26＂, ＂GV 20＂ and ＂GV 14＂ of governor vessel, and ＂Qìhǎi（气海 CV 6）＂, ＂Guānyuán（关元 CV 4）＂ and ＂Chéngjiāng（承浆 CV 24）＂ of conception vessel were selected; electroacupuncture device was connected with ＂GV 14＂ and ＂GV 20＂, ＂CV 4＂ and ＂CV 6＂. Neurological severity score was conducted.Enzyme linked immunosorbent assay（ELISA） was applied to determine the concentration of peripheral serum adrenocorticotropic hormone（ACTH） of rats, and immunohistochemical method was adopted to detect the expression levels of tumor necrosis factor α（TNF-α） and transforming growth factor β1（TGF-β1） in brain tissue of rats. The other 24 rats were also randomly divided into four groups mentioned above, 6 rats in each group, to detect cerebral ischemie volume. Results Compared with group B, the ischemia volume in brain tissue at 144 h after cerebral ischemia reperfusion decreased significantly in group C and group D（P〈0.05）, and the ischemia volume in group D was less than that in group C（P〈0.05）. The neurological impairment scores of group C and group D at all time points were lower than those of group B, and the differences were statistically significant（all P〈0.05）. The scores of group D at all time points were lower than those of group C, and the differences since 24 h were statistically significant（all P〈0.05）. Compared with group B, the excessive expression of ACTH was suppressed dynamically and generally in group C and group D（P〈0.05）; the expression level of TNF-α was down-regulated and TGF-β1 was up-regulated as well in group C and group D（P〈0.05）. The effect in group D was superior to that in group C. Conclusion Electroacupuncture at conception vessel and governor vessel can protect brain through the intervention of the expression of correlative signals of inflammatory response stress-injury-repair of cerebral ischemia reperfusion.
基金Supported by the Soft Science Project of the Science and Technology Agency of Jiangxi Province(20133BBA10017)the Planning Project for Arts and Social Sciences of Jiangxi Province~~
文摘In modern Chinese style garden, the designer could express the emotions in garden creation to produce artistic conception with landscape plants, which could make the sightseers desire to integrate with the nature and led to sympathizing with the concept, thereby motivating and arousing people＇s emotion to return to and close to nature. Through the 6 specific characteristics of ＂shape, color, aroma, shadow, sound and art＂ of landscape plants, some ways to build artistic conception in Chinese style garden were introduced in this study to provide references for the creation of artistic conception creation through senses in the future landscaping design.
基金Supported by Protection of Linpan Resources and Demonstration Protection of Bamboo Industry Chain Cultivation in West Sichuan under the Supervision of Sichuan Provincial Department of Science and Technology (2009FZ0028)~~
文摘This study explored the origin and development of modern garden city,by integrating concepts of world modern garden city and characteristics of Chengdu cultures,analyzed the application of its aesthetic value and the design of its artistic conception.It was found that Chengdu City had high aesthetic value such as a large area of green spaces and unique recreational cultures,as well as a great potential of unifying idyllic images and natural cultures.To design Chengdu into a world modern garden city,the planning of its urban green space system should be taken as the foundation,"one group and three districts" as the construction system,urban folk cultures,logistics and traffic,information and other such networks as the support to achieve the "beauty of nature,social equity and urban-rural integration".
文摘To better inherit traditional culture in creating artistic conception in modern gardens and develop the style and function of garden artistic conception,this study summarized various creation techniques of traditional garden artistic conceptions from the perspective of design thought and conception of classical Chinese gardens.It was put forward that the creation of artistic conception in modern gardens should be human-centered in a great culture context;and meanwhile,aesthetic habits of modern people should be respected and traditional thoughts should be developed to enrich the connotation of garden artistic conception design.
文摘Elementary knowledge of classical Chinese gardens was introduced,its history was studied in 3 stages:initial phase,development phase and prosperous phase,component system of classical Chinese gardens was introduced from different perspectives,cultural background and specific demonstrations of its artistic conceptions were expounded as key points,and it was proposed that its artistic conceptions were actually reverence and respect for the nature,and also expressions of various philosophical doctrines and religious cultures.On this basis,construction techniques and connotations of artistic conception were researched as well as its components and expression ways.It was proposed that construction elements of artistic conceptions included buildings,hill stones,water and plants;image-building in the landscaping should be stressed,and artistic conception integrated into key points to bring out the theme,garden scenes and paintings combined.This study aimed at providing references for relevant researches through introducing classical Chinese gardens and their artistic conceptions.
文摘In the field of second language acquisition, an increasing amount of research has been conducted on learner＇s beliefs. Few empirical studies, however, have been focused on students＇ conceptions of learning English （COLE）. This study aims to assess conceptions of learning particularly in the domain of English. Data were collected through the COLE questionnaire among 284 college students in China. Seven factors of COLE are identified, such as ＂memorizing＂, ＂testing＂, ＂drill and practice＂, ＂increasing knowledge＂, ＂understanding＂, ＂application＂, and ＂seeing in a new way＂. These findings also provide some pedagogical implications for English language instructors and researchers.
文摘Effective teaching has always been a goal pursued by teachers as a part of education both from the western and eastern society,for it to some extend is considered an effective way to improve society.In this essay,both Chinese and western conceptions of teaching and learning will be discussed.In doing so,their differences and similarities can be seen clearly,which will help the cross-cultural educators to understand their teaching environment and learning styles.
基金supported by the Federal Ministry of Education and Research(BMBF):“RiSKWa-Verbundprojekt PRiMaT:Praventives Risikomanagement in der Trinkwasserversorgung”(code:02WRS1279L).
文摘Any everyday subject may trigger individual conceptions either scientifically correct or naively shaped (misconceptions, alternative conceptions). For any educator, knowledge about a pupil’s individual perception may strongly support teaching success. Within this context, we see the use of drinking water as daily behavior loaded with conceptions. We monitored the perceptions of two different samples, of high achieving 10th graders and of undergraduates in Biology. All participants responded to three closed and three open questions requesting individual statements about drinking water. All open questions were categorized via qualitative content analysis mainly revealing the perception of drinking water as a clean product, precisely controlled and drinkable with no need for worry. In general, some alternative conceptions did not seem differ in both samples over the time of about five years: For instance, many see our drinking water as purified in sewage plants. However, differences between individuals exist: For example, whether water is consumed as tap or bottled water. Here, some name water hardness as the reason to not drink tap water, because they think it is harmful (although the very same participants prefer bottled mineral water). Other conceptions seem to change over time, such as the estimation about the remaining time until our drinking water might be used up, or familiarity with the term “virtual water”. Summing up, we did find a positive attitude towards national drinking water policy, although major knowledge gaps need its mentioning. The relevance of these results and strategies for public and school teaching are discussed.
基金supported by the National Natural Science Foundation of China,No.81072877Key Laboratory Project of Condition and Platform Construction Plan of Shenzhen Scientific Research Fund,No.CXB201111250113AShenzhen Scientific and Technology Development Program,No.201203149
文摘Mesenchymal stem cell transplantation is a novel means of treating cerebral ischemia/reper- fusion, and can promote angiogenesis and neurological functional recovery. Acupuncture at Conception and Governor vessels also has positive effects as a treatment for cerebral ischemia/ reperfusion. Therefore, we hypothesized that electro-acupuncture at Conception and Governor vessels plus mesenchymal stem cell transplantation may have better therapeutic effects on the promotion of angiogenesis and recovery of neurological function than either treatment alone. In the present study, human umbilical cord blood-derived mesenchymal stem cells were isolated, cultured, identified and intracranially transplanted into the striatum and subcortex of rats at 24 hours following cerebral ischemia/reperfusion. Subsequently, rats were electro-acupunctured at Conception and Governor vessels at 24 hours after transplantation. Modified neurological severity scores and immunohistochemistry findings revealed that the combined interventions of electro-acupuncture and mesenchymal stem cell transplantation clearly improved neurological impairment and up-regulated vascular endothelial growth factor expression around the isch- emic focus. The combined intervention provided a better outcome than mesenchymal stem cell transplantation alone. These findings demonstrate that electro-acupuncture at Conception and Governor vessels and mesenchymal stem cell transplantation have synergetic effects on promot- ing neurological function recovery and angiogenesis in rats after cerebral ischemia/reperfusion.
基金Supported by the National Natural Science Foundation of China(No.81072877)Shenzhen Municipal Science and Technology Research Development and Funds and Platform Construction Plan Key Laboratory Program(No.CXB201111250113A)Shenzhen Municipal Science and Technology Plan Project(No.201203149)
文摘OBJECTIVE: To investigate the combinatorial effects of conception and governor vessel electroacupuncture(EA) and human umbilical cord blood-derived mesenchymal stem cells(HUCB-MSCs) on pathomorphologic lesion and cellular apoptosis in rats with cerebral ischemia/reperfusion. METHODS: With the HUCB-MSCs isolated, cultured and identified and the models of cerebral ischemia-reperfusion established, the HUCB-MSCs of passage three were intracranially transplanted and the EA at conception and governor vessels was applied. The pathomorphologic lesion by hematoxylin-eosin staining and the cellular apoptosis by terminal deoxynucleotidyl transferase-mediated nick-end labeling method around the ischemic focus were observed. RESULTS: The cultured adherent HUCB-MSCs exhibited a spindle shape and expressed MSC-specific markers, with the cell purity and proliferation rate significantly increasing after the primary passage. HE staining showed that there were no pathological changes observed in the sham surgery group. However, in the PBS transplantation group, degeneration and necrosis of a great number of nerve cells were seen. In both the HUCB-MSCs transplantation group and the HUCB-MSCs transplantation + EA group, reparative changes of the pathomorphism of the tissue were found. Both combination treatment and simple MSCs treatment were able to improve the pathomorphorlogic lesion following cerebral ischemia and reduce the abnormal TUNEL-positive numbers, with former better than latter. CONCLUSION: HUCB-MSCs improve pathological lesions and inhibit the cellular apoptosis around the cerebral ischemic area. EA at conception and governor vessels also improve pathological lesion and inhibit the cellular apoptosis in rats treated with HUCB-MSCs transplantation, which effects were superior to that of simple HUCB-MSCs transplantation.
基金partially supported by Guangdong Innovative and Entrepreneurial Research Team Program (No. 201301S0105240297)by 111 Project
文摘Approximately 30% of pregnancies after implantation end up in spontaneous abortions, and 50% of them are caused by chromosomal abnormalities. However, the spectrum of genomic copy number variants （CNVs） in products of conception （POC） and the underlying gene- dosage-sensitive mechanisms causing spontaneous abortions remain largely unknown. In this study, array comparative genornic hybridiza- tion （aCGH） analysis was performed as a salvage procedure for 128 POC culture failure （POC-CF） samples and as a supplemental procedure for 106 POC normal karyotype （POC-NK） samples. Chromosomal abnormalities were detected in 10% of POC-CF and pathogenic CNVs were detected in 3.9% of POC-CF and 5.7% of POC-NK samples. Compiled results from this study and relevant case series through a literature review demonstrated an abnormality detection rate （ADR） of 35% for chromosomal abnormalities in POC-CF samples, 3.7% for pathogenic CNVs in POC-CF samples, and 4.6% for pathogenic CNVs in POC-NK samples. Ingenuity Pathway Analysis （IPA） was performed on the genes from pathogenic CNVs found in POC samples. The denoted primary gene networks suggested that apoptosis and cell proliferation pathways are involved in miscarriage. In summary, a similar spectrum of cytogenomic abnormalities was observed in POC culture success and POC-CF samples. A threshold effect correlating the number of dosage-sensitive genes in a chromosome with the observed frequency of autosomai trisomy is proposed. A rationalized approach using firstly fluorescence in situ hybridization （FISH） testing with probes of chromosomes X/Y/ 18, 13/21, and 15/16/22 for common aneuploidies and polyploidies and secondly aCGH for other cytogenomic abnormalities is recommended for POC-CF samples.
基金supported by doctoral grant PD/BD/113999/2015 from the Fundacao para a Ciência e Tecnologia and by the European Social Fund and the Portuguese Ministry of Science and Educationfunded by the Research Grants Council (Hong Kong SAR, China)project entitled “Characterizing researchers’ research agenda-setting: an international perspective across fields of knowledge” (project number: 27608516)。
文摘Purpose:In studies of the research process,the association between how researchers conceptualize research and their strategic research agendas has been largely overlooked.This study aims to address this gap.Design/methodology/approach:This study analyzes this relationship using a dataset of more than 8,500 researchers across all scientific fields and the globe.It studies the associations between the dimensions of two inventories:the Conceptions of Research Inventory(CoRI)and the Multi-Dimensional Research Agenda Inventory—Revised(MDRAI-R).Findings:The findings show a relatively strong association between researchers’conceptions of research and their research agendas.While all conceptions of research are positively related to scientific ambition,the findings are mixed regarding how the dimensions of the two inventories relate to one another,which is significant for those seeking to understand the knowledge production process better.Research limitations:The study relies on self-reported data,which always carries a risk of response bias.Practical implications:The findings provide a greater understanding of the inner workings of knowledge processes and indicate that the two inventories,whether used individually or in combination,may provide complementary analytical perspectives to research performance indicators.They may thus offer important insights for managers of research environments regarding how to assess the research culture,beliefs,and conceptualizations of individual researchers and research teams when designing strategies to promote specific institutional research focuses and strategies.Originality/value:To the best of the authors’knowledge,this is the first study to associate research agendas and conceptions of research.It is based on a large sample of researchers working worldwide and in all fields of knowledge,which ensures that the findings have a reasonable degree of generalizability to the global population of researchers.
文摘When the stagnation temperature of a perfect gas increases, the specific heats and their ratio do not remain constant any more and start to vary with this temperature. The gas remains perfect, its state equation remains always valid, except it will name in more calorically imperfect gas or gas at High Temperature. The goal of this research is to trace the profiles of the supersonic plug nozzle when this stagnation temperature is taken into account, lower than the threshold of dissociation of the molecules, by using the new formula of the Prandtl Meyer function, and to have for each exit Mach number, several nozzles shapes by changing the value of this temperature. A study on the error given by the PG （perfect gas） model compared to our model at high temperature is presented. The comparison is made with the case of a calorically perfect gas aiming to give a limit of application of this model. The application is for the air.
文摘Dairy heifers only start to produce a return on investment at first calving. The length of the non-productive rearing period is largely governed by farmer decisions on plane of nutrition and reproduction management. Primary data were collected from 101 dairy farms and a cost analysis workbook developed to calculate individual inputs in each of three periods to determine which management decisions and farm factors have the greatest influence on the total costs associated with rearing. This paper covers weaning until conception. Heifers were weaned at 62 d (range 42 - 112 d) and conceived by 509 d (range 365 - 700 d) giving an average weaning to conception period of 447 ± 60 d (range 253 to 630 d). The mean daily cost of rearing during this period was ￡1.65 (range ￡0.75 to ￡2.97 on different farms) giving a mean total cost of ￡745.94 per heifer (range ￡295.32 to ￡1745.85). This large variation was mostly due to the duration, which was mainly determined by age at first breeding (mean 476 days, range 365 - 700 d). The main contributors to total costs were feed (35.6%), labour (24.7%) and bedding (8.9%). The variables most strongly associated with the total costs were age at conception, calving pattern and breed. A multivariable model predicted an increase in mean cost of ￡2.26 for each extra day in age at conception. The total cost was highest in herds with all year round calving, intermediate in multi-block and lowest in spring and autumn calving herds, with Friesian x and Jersey herds having the lowest cost of rearing.
文摘Objective:Objective:To observe the therapeutic effect of cross-shaped moxibustion on the conception vessel and belt vessel for dysmenorrhea due to qi and blood deficiency.Methods:Taking Shenque(神阙CV8)as the center,up to Zhongwan(中脘CV12),down to Zhongji(中极CV3),and both sides to Daimai(带脉GB26),the above mentioned were treated area.The patient’s umbilicus was filled with the herbal powder for moxibustion and the powder was also scattered in a straight line along the treated area.The two sheets of mulberry paper were put in a cross way on the herbal powder for moxibustion,and the cross-shaped moxibustion box was put on the paper.The ginger paste was put into the box to a height of 3 cm and pressed tightly with a tongue depressor,the margin of the ginger paste should be clinged to the moxibustion box.The moxa cones were put end to end in the groove on the median of the ginger paste and ignited orderly.When the cones were burnt completely,the new cones were used and ignited.Three cones were adopted in succession in each treatment.The treatment was given once a week,and three treatments as one course,the therapeutic effect was evaluated after two courses of treatment.Results:There were 16 cases cured,5 cases effective and 2 cases non-effective in all.The total effective rate was 91.3%.Conclusion:Coss-shaped moxibustion on the conception vessel and belt vessel has sound effect for dysmenorrhea due to qi and blood deficiency.
文摘[Objective] Taking the knowledge of tea-science field as research object,an extraction method for the taxonomic relation of ontology conception was proposed in the paper.[Method] Through improving the rule based on language mode,generalized suffix tree was constructed for the concept set of tea-science field,forming hierarchical structure and taxonomic relation among conceptions.[Result and Conclusion] Moreover,corresponding prototype system was developed based on above method,and test result indicating that the method was effective.
基金This paper is sponsored by the Postgraduate Creative Foundation of Gannan Normal University entitled“模因论视域下康达维辞赋译本中文化负载词的英译研究”(YCX20A042).
文摘Chinese classical poetry has long been known for its unique artistic conception of mixture of sentiments andscenery, the conception beyond image and the refinement out of rhyme. From the perspective of receptionaesthetics theory, this paper analyzes translation strategies of the classical poetry, probes into the problems thatretaining “indeterminacy” and satisfying the readers “horizon of expectations” when translate Chinese classicalpoetry. It is necessary to keep enough aesthetic space, and to give full play to the translator’s aesthetic creativitywhen translate Chinese classical poetry, so as to reproduce the artistic conception of Chinese classical poetry.
文摘The theme of the Conception of the Virgin Mary fascinated 16th-century Mannerist painters, as manifested in Giorgio Vasari＇s many drawings and paintings and also the numerous replicas in drawings, paintings, and engravings made after his paintings by his contemporary artists. This essay focuses on Vasari＇s complex iconography of The Conception of Our Lady of 1540 at SS. Apostoli in Florence, Italy. In his documentation of the painting, Vasari never referred to or entitled the painting as an Allegory of the Immaculate Conception or Immaculate Conception but coined it as The Conception of Our Lady （Concezione di Nostra Donna） as it will be referred in this essay. Vasari＇s complex iconography derived from the writings of the A retine canon Giovanni Pollastra. The Virgin Mary is depicted as a victorious symbol of grace and salvation, triumphing over evil. Rejoicing angels surround her with scrolls containing Latin inscriptions, QUOS EVE CULPA DAAVIT/MARIAE GRATIAE SOLVIT, ECCE AGNIU[S] and UNIUS ONNOSTAA. These joyful words allude to the restoration of the fate of Adam and Eve after eating the forbidden fruit from the Tree of Knowledge in Paradise. A sinuous serpent coils around the fig tree, while tied-up Old Testament and New Testaments wait for forgiveness and salvation. Three considerations are addressed in this essay： （1） discussion of Vasari＇s recorded commissions; （2） stylistic observations and influences; and （3） interpretation of the imagery, that is, some observations on the symbolism of the painting.
文摘After the September 11th events and especially after the follow-updevelopment of the US-Russian relationship,many Americangovernment officials in the Bush team stated time and again in
