Recently,the Royal Swedish Academy of Sciences announced that one-half of the 2024 Nobel Prize in Chemistry was awarded to David Baker for computational protein design,and the other half was awarded jointly to Demis H...Recently,the Royal Swedish Academy of Sciences announced that one-half of the 2024 Nobel Prize in Chemistry was awarded to David Baker for computational protein design,and the other half was awarded jointly to Demis Hassabis and John Jumper for protein structure prediction.Proteins are the molecule tools of life.To carry out their functions,many proteins need to fold into particular three-dimensional(3D)structures,which are programmed by the amino acid sequences of the proteins[1].The goal of protein structure prediction is to predict the 3D structures from given amino acid sequences.Conversely,protein design aims to identify amino acid sequences that achieve desired structural or functional goals.展开更多
文摘Recently,the Royal Swedish Academy of Sciences announced that one-half of the 2024 Nobel Prize in Chemistry was awarded to David Baker for computational protein design,and the other half was awarded jointly to Demis Hassabis and John Jumper for protein structure prediction.Proteins are the molecule tools of life.To carry out their functions,many proteins need to fold into particular three-dimensional(3D)structures,which are programmed by the amino acid sequences of the proteins[1].The goal of protein structure prediction is to predict the 3D structures from given amino acid sequences.Conversely,protein design aims to identify amino acid sequences that achieve desired structural or functional goals.
