Complementary inverter is the basic unit for logic circuits,but the inverters based on full oxide thin-film transistors(TFTs)are still very limited.The next challenge is to realize complementary inverters using homoge...Complementary inverter is the basic unit for logic circuits,but the inverters based on full oxide thin-film transistors(TFTs)are still very limited.The next challenge is to realize complementary inverters using homogeneous oxide semiconduc-tors.Herein,we propose the design of complementary inverter based on full ZnO TFTs.Li-N dual-doped ZnO(ZnO:(Li,N))acts as the p-type channel and Al-doped ZnO(ZnO:Al)serves as the n-type channel for fabrication of TFTs,and then the complemen-tary inverter is produced with p-and n-type ZnO TFTs.The homogeneous ZnO-based complementary inverter has typical volt-age transfer characteristics with the voltage gain of 13.34 at the supply voltage of 40 V.This work may open the door for the development of oxide complementary inverters for logic circuits.展开更多
Nausea and vomiting are physiological responses that react to various bodily conditions and play a protective function.Medicinal and nonmedicinal methods,including complementary medicine,treat nausea and vomiting.The ...Nausea and vomiting are physiological responses that react to various bodily conditions and play a protective function.Medicinal and nonmedicinal methods,including complementary medicine,treat nausea and vomiting.The current research aims to investigate the effectiveness of foot reflexology as a complementary medicine method for nausea and vomiting.Based on PRISMA 2020,PubMed,Web of Science,and Scopus were searched until October 2,2024,using a search strategy approved by two researchers.Only randomized controlled trial studies were included in this research.No limitations or filters were applied.The inclusion criteria were selected based on the PICOS framework,and the studies were evaluated according to the National Institutes of Health quality assessment tool,which is related to controlled intervention,and were evaluated by two researchers.Finally,six studies were included in this review.Eighty-four percent of studies were conducted in Asia.Three records are from Iran,and two are from Turkey,and one is from France.The results showed that nausea and vomiting improved in all studies.In most studies(67%),four sessions or less led to improved outcomes.Rhodes index of nausea,vomiting,and retching and visual analog scale were utilized to assess nausea and vomiting.The current systematic review indicated that foot reflexology as a noninvasive intervention could improve nausea and vomiting in patients with cancer problems,pregnancy,hemodialysis,and laparoscopic cholecystectomy。展开更多
As the power system transitions to a new green and low-carbon paradigm,the penetration of renewable energy in China’s power system is gradually increasing.However,the variability and uncertainty of renewable energy o...As the power system transitions to a new green and low-carbon paradigm,the penetration of renewable energy in China’s power system is gradually increasing.However,the variability and uncertainty of renewable energy output limit its profitability in the electricity market and hinder its market-based integration.This paper first constructs a wind-solar-thermalmulti-energy complementary system,analyzes its external game relationships,and develops a bi-level market optimization model.Then,it considers the contribution levels of internal participants to establish a comprehensive internal distribution evaluation index system.Finally,simulation studies using the IEEE 30-bus system demonstrate that the multi-energy complementary system stabilizes nodal outputs,enhances the profitability of market participants,and promotes the market-based integration of renewable energy.展开更多
BACKGROUND Adult-onset Still's disease(AOSD)is a rare autoinflammatory disease charac-terized by nonspecific symptoms such as fever,rash,sore throat and arthralgia.This paper reports a clinical case of AOSD succes...BACKGROUND Adult-onset Still's disease(AOSD)is a rare autoinflammatory disease charac-terized by nonspecific symptoms such as fever,rash,sore throat and arthralgia.This paper reports a clinical case of AOSD successfully treated with Bo’s abdo-minal acupuncture(BAA).CASE SUMMARY We report a 20-year-old man who suffered from cold exposure,presenting with high fever,rash,sore throat,arthralgia,and elevated erythrocyte sedimentation rate,leukocytosis with neutrophilic predominance,elevated ferritin,elevated C-reactive protein,and negative rheumatoid factors.He was diagnosed with AOSD based on the Yamaguchi criteria.After treatment with traditional Chinese medi-cine(TCM)decoction and prednisone acetate tablets,there was some alleviation of sore throat,joint and muscle pain,and fever,but he still had persistent low-grade fever,rash,sore throat and arthralgia.He went to the TCM acupuncture outpatient department to receive BAA.Abdominal acupoints Zhongwan(CV12),Xiawan(CV10),0.5 cm below Xiawan(CV10),Qihai(CV6),Guanyuan(CV4),bilateral Qixue(KI13),bilateral Huaroumen(ST24),bilateral Shangfengshidian(AB1)and bilateral Daheng(SP15)were selected.After 3 months treatment,all symptoms disappeared,and the laboratory examination returned to normal levels.He did not take glucocorticoids or nonsteroidal anti-inflammatory drugs afterwards,and no relapse was observed during the 3-year follow-up period.CONCLUSION BAA can be used as a complementary medical approach for treatment of AOSD.展开更多
Evaluation of a Commercially Available Radiochromic Film for Use as a Complementary Dosimeter for Rapid In-field Low Photon Equivalent Radiation Dose (≤50 mSv) Monitoring Nicky Nivi1, Helen Moise1,2, Ana Pejovic'...Evaluation of a Commercially Available Radiochromic Film for Use as a Complementary Dosimeter for Rapid In-field Low Photon Equivalent Radiation Dose (≤50 mSv) Monitoring Nicky Nivi1, Helen Moise1,2, Ana Pejovic'-Milic'1(1. Department of Physics, Toronto Metropolitan University, 350 Victoria Street, Toronto, Ontario, M5B 2K3;2. Autonomous and Radiological Technologies Section, Defense Research and Development Canada, PO Box 4000 Stn Main,Medicine Hat, Alberta, T1A 8K6).展开更多
AlphaPanda(AlphaFold2[1]inspired protein-specific antibody design in a diffusional manner)is an advanced algorithm for designing complementary determining regions(CDRs)of the antibody targeted the specific epitope,com...AlphaPanda(AlphaFold2[1]inspired protein-specific antibody design in a diffusional manner)is an advanced algorithm for designing complementary determining regions(CDRs)of the antibody targeted the specific epitope,combining transformer[2]models,3DCNN[3],and diffusion[4]generative models.展开更多
Infancy and toddlerhood are critical phases of life,as the gut microbiota is established here,which influences current and future health.During this period,the microbiota was relatively less stable and highly responsi...Infancy and toddlerhood are critical phases of life,as the gut microbiota is established here,which influences current and future health.During this period,the microbiota was relatively less stable and highly responsive to environmental factors.Therefore,it is important to understand how dietary factors affect this complex stage of microbial assembly.The effect of feeding practices(breast milk/formula) on microbial colonization in early infancy has been actively studied;however,studies on the effect of diet on the gut microbiota during the complementary feeding period are sparse.The introduction of complementary foods provides abundant new dietary compounds for the gut microbiota,which induces a shift in gut microbiota and metabolism from milk-adapted toward a more mature and diverse adult-like community.Herein,we discuss the impact of dietary nutrients(carbohydrates,proteins,fats,vitamins,and minerals) on microbiome of infants and toddlers.Furthermore,this review summarizes the effects of complementary feeding patterns,specific foods(such as cereals;legumes and nuts;vegetables and fruits;meats;dairy products),food additives,and malnutrition(undernutrition or overnutrition) on gut microbiota of this populations.These findings might deepen our comprehension of the complex interactions between diets and the development and establishment of the gut microbiota.This may facilitate the tailoring of interventions aimed at promoting beneficial modifications within the gut microbial community.Furthermore,the insights gained could inform the design and implementation of safe and efficacious complementary feeding practices.展开更多
To improve image quality under low illumination conditions,a novel low-light image enhancement method is proposed in this paper based on multi-illumination estimation and multi-scale fusion(MIMS).Firstly,the illuminat...To improve image quality under low illumination conditions,a novel low-light image enhancement method is proposed in this paper based on multi-illumination estimation and multi-scale fusion(MIMS).Firstly,the illumination is processed by contrast-limited adaptive histogram equalization(CLAHE),adaptive complementary gamma function(ACG),and adaptive detail preserving S-curve(ADPS),respectively,to obtain three components.Then,the fusion-relevant features,exposure,and color contrast are selected as the weight maps.Subsequently,these components and weight maps are fused through multi-scale to generate enhanced illumination.Finally,the enhanced images are obtained by multiplying the enhanced illumination and reflectance.Compared with existing approaches,this proposed method achieves an average increase of 0.81%and 2.89%in the structural similarity index measurement(SSIM)and peak signal-to-noise ratio(PSNR),and a decrease of 6.17%and 32.61%in the natural image quality evaluator(NIQE)and gradient magnitude similarity deviation(GMSD),respectively.展开更多
Background:The use of complementary and alternative medicine(CAM)is common among individuals with underlying chronic illnesses.Objective:This systematic review and meta-analysis investigated the global prevalence and ...Background:The use of complementary and alternative medicine(CAM)is common among individuals with underlying chronic illnesses.Objective:This systematic review and meta-analysis investigated the global prevalence and patterns of CAM use among individuals with chronic kidney disease(CKD).Search strategy:PubMed,Embase,and Cumulative Index to Nursing and Allied Health Literature Plus were searched from inception until 26th February 2024.Inclusion criteria:Original articles reporting the use of at least one type of CAM among individuals aged above 18 years old and at all stages of CKD or undergoing any form of kidney replacement therapy.Data extraction and analysis:Two independent reviewers performed the literature screening.The data were extracted from the included studies by one reviewer and cross-checked by another.Discrepancies were resolved by discussion and consensus among two reviewers.Primary information included prevalence of CAM use,types of CAM used,reasons for CAM use,factors associated with CAM use,and disclosure to healthcare providers.Meta-analyses were performed to determine the pooled prevalence of CAM use and non-disclosure of CAM using a random effect model.Results:Forty-one studies were included in this systematic review and meta-analysis.The pooled prevalence of CAM use was 43%(95%confidence interval:34%,51%),I2=99.46%.The reasons for CAM use included treatment of underlying comorbidities,complications or symptoms,maintenance of general health,and treatment of CKD.Nutritional approaches were the most common CAM modality,with 412different herbal and dietary supplements reported;psychological and physical approaches included massage therapy,relaxation techniques,and mind–body practices;and other complementary health approaches such as homeopathy,traditional Chinese medicine,and Ayurvedic medicine were also frequently reported.Factors associated with CAM use included sociodemographic characteristics such as older age,female gender,or higher income;disease or therapy factors such as not having diabetes,relying on hemodialysis,or poor adherence to medication;and patient or internal factors such as positive attitude towards CAM and perceived safety of CAM.About 66%(61%,72%)of CAM users did not disclose the use of CAM to their healthcare providers.Conclusion:CAM use is prevalent among individuals with CKD,and healthcare providers should communicate openly and effectively to emphasize the rational use of CAM to avoid potential harm.展开更多
Mild electrocatalytic nitrate reduction reaction(NO_(3)RR),driven by renewable electricity,is regarded as a desirable strategy for green ammonia synthesis and simultaneous removal of nitrogen-containing environmental ...Mild electrocatalytic nitrate reduction reaction(NO_(3)RR),driven by renewable electricity,is regarded as a desirable strategy for green ammonia synthesis and simultaneous removal of nitrogen-containing environmental pollutants.In view of different supply voltages from renewable energy sources,developing costeffective and efficient electrocatalysts with a wide operating potential window is very meaningful for practical application.However,currently reported catalysts usually need to introduce noble metals to synergistically achieve wide-potential selective ammonia synthesis from nitrate.In this work,we present for the first time a dual-transition-metal electrocatalyst(Fe_(3)C-CuO_(x)@NC,x=0,1)with wide-potential-adaptability for highly selective nitrate reduction to ammonia.Such Fe_(3)C-CuO_(x)@NC with spatially separated CuO_(x)and noblemetal-like Fe_(3)C nanoparticles encapsulated with nitrogen-doped graphitized carbon,exhibits outstanding performance in NO_(3)RR with desirable NH_(3)Faraday efficiency of more than 90%over a wide potential ranging from-0.2 V vs.RHE to-0.6 V vs.RHE,comparable to the reported noble metal catalysts.Different from common tandem catalysis,the wide-potential high ammonia selectivity of Fe_(3)C-CuO_(x)@NC is domina ntly ascribed to the complementary enhancement between CuO_(x)and Fe_(3)C,fully supported by results of experiments and density function theory calculations.CuO_(x)exhibit highly intrinsic nitrate reduction to nitrite to compensate for the slow potential determination step(^(*)NO_(3)→^(*)NO_(3)H)of Fe_(3)C,while Fe_(3)C,besides behaving like noble metals to supply adequate active hydrogens,has both good adsorption and reduction abilities for nitrite species to ammonia.Moreover,Fe_(3)C partially stabilizes active Cu^(0)/Cu^(+)sites,and the unique carbon-layer enca psulation structure effectively prevents the agglomeration and corrosion of metal nanoparticles during the electrocatalysis,thus maintaining good cyclic stability.The Zn-NO_(3)^(-)battery assembled with Fe_(3)C-CuO_(x)@NC can reach a high power density of 5.2 mW cm^(-2)at a potential of 1.0 V vs.Zn,with an NH_(3)Faraday efficiency of 92.4%at a current of 8.0 mA,proving its potential practical application.This advance provides unique insights into complementary catalysis mechanisms on multiple metal sites in NO_(3)RR,and offers a reference for the design of other transition metal electrocatalysts matching with renewable electricity.展开更多
BACKGROUND Prediabetes is a high-risk precursor for diabetes development and is associated with increased psychological distress.Conventional pharmacological treatments for prediabetes have limitations,including adver...BACKGROUND Prediabetes is a high-risk precursor for diabetes development and is associated with increased psychological distress.Conventional pharmacological treatments for prediabetes have limitations,including adverse effects and poor patient compliance.Tuina’s abdominal vibration technique,a traditional non-pharmacological intervention,has shown promising results in glycemic regulation.However,its effects on psychological well-being remain largely unexplored.AIM To investigate efficacy of abdominal vibration at varying frequencies in Tuina for alleviating psychological and metabolic effects in prediabetes patients.METHODS A prospective cohort study(April 2025 to April 2026)at Dongfang Hospital of Beijing University of Chinese Medicine included 120 prediabetes patients.Participants were allocated to three groups based on vibration frequency:(1)Lowfrequency(400 times/minute,n=40);(2)Medium-frequency(500 times/minute,n=40);and(3)High-frequency(600 times/minute,n=40).All participants received 30-minute sessions three times weekly for 3 months,with follow-up at 6 months and 12 months.Primary outcomes included changes in depression(Beck Depression Inventory-Ⅱ),anxiety(State-Trait Anxiety Inventory),and stress(Perceived Stress Scale)levels.RESULTS After a 3-month intervention period,with follow-ups at 6 months and 12 months,patients in all three groups showed significant improvements in depression,anxiety,and stress scores compared to baseline(P<0.001).The high-frequency group demonstrated the most substantial psychological improvements(mean reduction in depression scores:9.2±2.3 points;anxiety:8.7±2.1 points;stress:10.4±2.5 points).These psychological improvements correlated significantly with reductions in insulin resistance(r=0.68,P<0.001).The high-frequency group also showed the most significant improvements in glycemic parameters,with mean reductions in fasting plasma glucose,2-hour postprandial glucose,and glycosylated hemoglobin concentrations of 0.92 mmol/L,1.87 mmol/L,and 0.51%,respectively.Correlation analysis revealed significant associations between improved psychological parameters and enhanced glycemic control.CONCLUSION Tuina’s abdominal vibration technique,especially at high frequency reduces depression,anxiety,and stress in prediabetes patients,correlating with enhanced glycemic control and insulin sensitivity,suggesting a bidirectional relationship between psychological and metabolic health.展开更多
Gait,the unique pattern of how a person walks,has emerged as one of the most promising biometric features in modern intelligent sensing.Unlike fingerprints or facial characteristics,gait can be captured unobtrusively ...Gait,the unique pattern of how a person walks,has emerged as one of the most promising biometric features in modern intelligent sensing.Unlike fingerprints or facial characteristics,gait can be captured unobtrusively and at a distance,without requiring the subject’s awareness or cooperation.This makes it highly suitable for long-range surveillance,forensic investigation,and smart environments where contactless recognition is crucial.Traditional gait-recognition systems rely either on silhouettes,which capture the outer appearance of a person,or on skeletons,which describe the internal structure of human motion.Each modality provides only a partial understanding of gait.Silhouettes emphasize shape and contour but are easily distorted by clothing or carried objects;skeletons describe motion dynamics and limb coordination but lose discriminative details about body shape.This article presents the concept of Complementary Semantic Embedding(CSE),a unified framework that merges silhouette and skeleton information into a comprehensive semantic representation of human walking.By modeling the complementary nature of appearance and structure,the approach achieves more robust and accurate gait recognition even under challenging conditions.展开更多
clear requirements for vigorously inheriting and developing traditional Chinese medicine,which should be an important part of the domestic healthcare system.Electroacupuncture,as a complementary therapy,has significan...clear requirements for vigorously inheriting and developing traditional Chinese medicine,which should be an important part of the domestic healthcare system.Electroacupuncture,as a complementary therapy,has significant efficacy and potential in the field of enhanced recovery after surgery based on current available evidence.Despite some challenges,electroacupuncture is expected to play a greater role in healthcare practice through policy support and technological innovation in the future under the“Healthy China 2030”plan.展开更多
Globally,the integration of traditional medicine and modern medicine has been recognized as a global health priority aimed at improving healthcare accessibility,cultural relevance,and therapeutic effectiveness.This re...Globally,the integration of traditional medicine and modern medicine has been recognized as a global health priority aimed at improving healthcare accessibility,cultural relevance,and therapeutic effectiveness.This review systematically examines the global landscape of traditional medicine-modern medicine integration by analyzing policy developments,regulatory frameworks,and clinical implementation models across various regions,including Asia,Africa,Europe,and the USA.The scope of the review encompasses five key domains:(1)global policy initiatives,(2)regulatory and institutional frameworks,(3)clinical integration models,(4)impacts and outcomes of integrative practices,and(5)challenges and barriers to implementation.Based on peer-reviewed literature and official health policy documents published between 2000 and 2025,the present review investigates how countries have operationalized clinical integration models combining traditional and complementary medicine.Although interest in traditional and complementary medicine has grown worldwide,persistent challenges,such as limited scientific validation,lack of standardization,and professional resistance,continue to hinder progress.This review concludes that successful and sustainable integration requires evidence-based clinical approaches,inclusive regulatory reforms,and coordinated policy strategies.Countries such as China,India,and Brazil have made significant advances,offering valuable models for future implementation worldwide.展开更多
Under the current long-term electricity market mechanism,new energy and thermal power face issues such as deviation assessment and compression of generation space.The profitability of market players is limited.Simulta...Under the current long-term electricity market mechanism,new energy and thermal power face issues such as deviation assessment and compression of generation space.The profitability of market players is limited.Simultaneously,the cooperation model among various energy sources will have a direct impact on the alliance’s revenue and the equity of income distribution within the alliance.Therefore,integrating new energy with thermal power units into an integrated multi-energy complementary system to participate in the long-term electricity market holds significant potential.To simulate and evaluate the benefits and internal distribution methods of a multi-energy complementary system participating in long-term market transactions,this paper first constructs a multi-energy complementary system integrated with new energy and thermal power generation units at the same connection point,and participates in the annual bilateral game as a unified market entity to obtain the revenue value under the annual bilateral market.Secondly,based on the entropy weight method,improvements are made to the traditional Shapley value distribution model,and an internal distribution model for multi-energy complementary systems with multiple participants is constructed.Finally,a Markov Decision Process(MDP)evaluation system is constructed for practical case verification.The research results show that the improved Shapley value distribution model achieves higher satisfaction,providing a reasonable allocation scheme for multi-energy complementary cooperation models.展开更多
Emerging two-dimensional(2D)semiconductors are among the most promising materials for ultra-scaled transistors due to their intrinsic atomic-level thickness.As the stacking process advances,the complexity and cost of ...Emerging two-dimensional(2D)semiconductors are among the most promising materials for ultra-scaled transistors due to their intrinsic atomic-level thickness.As the stacking process advances,the complexity and cost of nanosheet field-effect transistors(NSFETs)and complementary FET(CFET)continue to rise.The 1 nm technology node is going to be based on Si-CFET process according to international roadmap for devices and systems(IRDS)(2022,https://irds.ieee.org/),but not publicly confirmed,indicating that more possibilities still exist.The miniaturization advantage of 2D semiconductors motivates us to explore their potential for reducing process costs while matching the performance of next-generation nodes in terms of area,power consumption and speed.In this study,a comprehensive framework is built.A set of MoS2 NSFETs were designed and fabricated to extract the key parameters and performances.And then for benchmarking,the sizes of 2D-NSFET are scaled to a extent that both of the Si-CFET and 2D-NSFET have the same average device footprint.Under these conditions,the frequency of ultra-scaled 2D-NSFET is found to improve by 36%at a fixed power consumption.This work verifies the feasibility of replacing silicon-based CFETs of 1 nm node with 2D-NSFETs and proposes a 2D technology solution for 1 nm nodes,i.e.,“2D eq 1 nm”nodes.At the same time,thanks to the lower characteristic length of 2D semiconductors,the miniaturized 2D-NSFET achieves a 28%frequency increase at a fixed power consumption.Further,developing a standard cell library,these devices obtain a similar trend in 16-bit RISC-V CPUs.This work quantifies and highlights the advantages of 2D semiconductors in advanced nodes,offering new possibilities for the application of 2D semiconductors in high-speed and low-power integrated circuits.展开更多
Carbon fiber reinforced polymer(CFRP)are widely used in various fields because of their high strength,good toughness,and low density.However,owing to their unique forming process,some complex structures such as holes ...Carbon fiber reinforced polymer(CFRP)are widely used in various fields because of their high strength,good toughness,and low density.However,owing to their unique forming process,some complex structures such as holes and grooves cannot be formed directly.Therefore,traditional machining procedures are also required.The drilling process is one of the most common machining methods for CFRP holes,but owing to the complex structure and difficulty in processing CFRP,the quality of the drilling process is often challenging to guarantee.Moreover,the hole-forming defects also have complex forms and lack uniform evaluation indexes.This study summarizes the common orifice defects in the process of CFRP drilling,establishes a comprehensive evaluation method of orifice defects by introducing the relevant theory of the fuzzy complementary judgment matrix,and experimentally verifies the accuracy and reliability of this method.Then,based on the experimental results,a non-linear cutting parameter optimization model is established,which effectively suppresses the orifice defects to ensure the accuracy of the hole size,roundness,and hole wall roughness.The hole-forming quality is subsequently improved.The hole quality evaluation method proposed in this study reduced the dimension of the evaluation index to ensure relevance and effectiveness and improved the convenience of quality inspection and parameter optimization in actual production.展开更多
The international scientific literature presents still incipient results regarding the management of cancer symptom clusters by oncology nursing,especially in pediatric oncology.This is a promising field of investigat...The international scientific literature presents still incipient results regarding the management of cancer symptom clusters by oncology nursing,especially in pediatric oncology.This is a promising field of investigation for clinical nurses and researchers,and when it is subsidized by medium-range theories,they co-rroborate the diagnoses and interventions of nursing in oncology,enhancing the science of nursing care.This minireview article aims to discuss the utilizing the hospital clowns as a complementary therapy,to enhance quality of life and reduce stress and fatigue in pediatric cancer patients.Overall,the evidence presented so far pointed out that complementary therapy might help improve the quality of life of pediatric cancer patients,and that complementary therapy usage should be part of a health comprehensive care model,delivering therapeutic approaches that might enhance the mind-body during a pediatric cancer patients’life span.The results of scientific investigations by nurses,particularly those linked to the basic sciences,play a critical role in advancing personalized care in pediatric integrative oncology.展开更多
This editorial is based on the network pharmacology and in vivo study by Qin et al,which investigated the potential therapeutic mechanisms of Panax ginseng(P.ginseng)in ulcerative colitis.The key findings from the stu...This editorial is based on the network pharmacology and in vivo study by Qin et al,which investigated the potential therapeutic mechanisms of Panax ginseng(P.ginseng)in ulcerative colitis.The key findings from the study included the identification of the targets of P.ginseng and ulcerative colitis,elucidation of mechanistic pathways,and in vivo validation of the pharmacological activity and therapeutic effect of panaxadiol,a key active component of P.ginseng.This editorial provides additional context regarding the evidence supporting the use of ginseng and other commonly used complementary therapies that clinicians may encounter.We also aim to highlight potential similarities between the mechanisms of popular complementary and conventional medical therapies.展开更多
Intermittent fasting(IF)has emerged as a potential adjunctive strategy in cancer prevention,mitigation,and treatment.This narrative review synthesizes existing literature to explore the relationship between IF and can...Intermittent fasting(IF)has emerged as a potential adjunctive strategy in cancer prevention,mitigation,and treatment.This narrative review synthesizes existing literature to explore the relationship between IF and cancer across 3 dimensions:prevention,mitigation,and treatment.We examine the underlying mechanisms by which IF may reduce cancer risk,including its effects on insulin-like growth factor 1 suppression,autophagy induction,and chronic inflammation reduction.Furthermore,we discuss IF’s potential to enhance the efficacy of conventional cancer therapies by sensitizing cancer cells,promoting apoptosis,and reducing treatmentrelated side effects.While promising,the evidence is still limited,and further research is required to elucidate the long-term impact and optimal implementation of IF in cancer care.This review aims to provide health care professionals and patients with a comprehensive understanding of the potential benefits and risks associated with IF as a complementary approach in the oncology setting.展开更多
基金supported by Zhejiang Provincial Natural Science Foundation of China(No.LZ24E020001).
文摘Complementary inverter is the basic unit for logic circuits,but the inverters based on full oxide thin-film transistors(TFTs)are still very limited.The next challenge is to realize complementary inverters using homogeneous oxide semiconduc-tors.Herein,we propose the design of complementary inverter based on full ZnO TFTs.Li-N dual-doped ZnO(ZnO:(Li,N))acts as the p-type channel and Al-doped ZnO(ZnO:Al)serves as the n-type channel for fabrication of TFTs,and then the complemen-tary inverter is produced with p-and n-type ZnO TFTs.The homogeneous ZnO-based complementary inverter has typical volt-age transfer characteristics with the voltage gain of 13.34 at the supply voltage of 40 V.This work may open the door for the development of oxide complementary inverters for logic circuits.
文摘Nausea and vomiting are physiological responses that react to various bodily conditions and play a protective function.Medicinal and nonmedicinal methods,including complementary medicine,treat nausea and vomiting.The current research aims to investigate the effectiveness of foot reflexology as a complementary medicine method for nausea and vomiting.Based on PRISMA 2020,PubMed,Web of Science,and Scopus were searched until October 2,2024,using a search strategy approved by two researchers.Only randomized controlled trial studies were included in this research.No limitations or filters were applied.The inclusion criteria were selected based on the PICOS framework,and the studies were evaluated according to the National Institutes of Health quality assessment tool,which is related to controlled intervention,and were evaluated by two researchers.Finally,six studies were included in this review.Eighty-four percent of studies were conducted in Asia.Three records are from Iran,and two are from Turkey,and one is from France.The results showed that nausea and vomiting improved in all studies.In most studies(67%),four sessions or less led to improved outcomes.Rhodes index of nausea,vomiting,and retching and visual analog scale were utilized to assess nausea and vomiting.The current systematic review indicated that foot reflexology as a noninvasive intervention could improve nausea and vomiting in patients with cancer problems,pregnancy,hemodialysis,and laparoscopic cholecystectomy。
基金funded by the National Key R&D Program of China,grant number 2019YFB1505400.
文摘As the power system transitions to a new green and low-carbon paradigm,the penetration of renewable energy in China’s power system is gradually increasing.However,the variability and uncertainty of renewable energy output limit its profitability in the electricity market and hinder its market-based integration.This paper first constructs a wind-solar-thermalmulti-energy complementary system,analyzes its external game relationships,and develops a bi-level market optimization model.Then,it considers the contribution levels of internal participants to establish a comprehensive internal distribution evaluation index system.Finally,simulation studies using the IEEE 30-bus system demonstrate that the multi-energy complementary system stabilizes nodal outputs,enhances the profitability of market participants,and promotes the market-based integration of renewable energy.
基金Supported by Beijing Municipal Commission of Education,No.SM202214075001。
文摘BACKGROUND Adult-onset Still's disease(AOSD)is a rare autoinflammatory disease charac-terized by nonspecific symptoms such as fever,rash,sore throat and arthralgia.This paper reports a clinical case of AOSD successfully treated with Bo’s abdo-minal acupuncture(BAA).CASE SUMMARY We report a 20-year-old man who suffered from cold exposure,presenting with high fever,rash,sore throat,arthralgia,and elevated erythrocyte sedimentation rate,leukocytosis with neutrophilic predominance,elevated ferritin,elevated C-reactive protein,and negative rheumatoid factors.He was diagnosed with AOSD based on the Yamaguchi criteria.After treatment with traditional Chinese medi-cine(TCM)decoction and prednisone acetate tablets,there was some alleviation of sore throat,joint and muscle pain,and fever,but he still had persistent low-grade fever,rash,sore throat and arthralgia.He went to the TCM acupuncture outpatient department to receive BAA.Abdominal acupoints Zhongwan(CV12),Xiawan(CV10),0.5 cm below Xiawan(CV10),Qihai(CV6),Guanyuan(CV4),bilateral Qixue(KI13),bilateral Huaroumen(ST24),bilateral Shangfengshidian(AB1)and bilateral Daheng(SP15)were selected.After 3 months treatment,all symptoms disappeared,and the laboratory examination returned to normal levels.He did not take glucocorticoids or nonsteroidal anti-inflammatory drugs afterwards,and no relapse was observed during the 3-year follow-up period.CONCLUSION BAA can be used as a complementary medical approach for treatment of AOSD.
文摘Evaluation of a Commercially Available Radiochromic Film for Use as a Complementary Dosimeter for Rapid In-field Low Photon Equivalent Radiation Dose (≤50 mSv) Monitoring Nicky Nivi1, Helen Moise1,2, Ana Pejovic'-Milic'1(1. Department of Physics, Toronto Metropolitan University, 350 Victoria Street, Toronto, Ontario, M5B 2K3;2. Autonomous and Radiological Technologies Section, Defense Research and Development Canada, PO Box 4000 Stn Main,Medicine Hat, Alberta, T1A 8K6).
基金supported by the Key Project of International Cooperation of Qilu University of Technology(Grant No.:QLUTGJHZ2018008)Shandong Provincial Natural Science Foundation Committee,China(Grant No.:ZR2016HB54)Shandong Provincial Key Laboratory of Microbial Engineering(SME).
文摘AlphaPanda(AlphaFold2[1]inspired protein-specific antibody design in a diffusional manner)is an advanced algorithm for designing complementary determining regions(CDRs)of the antibody targeted the specific epitope,combining transformer[2]models,3DCNN[3],and diffusion[4]generative models.
基金supported by the National Natural Science Foundation of China (32122067 and 32021005)supported by the Fundamental Research Funds for the Central Universities (JUSRP622013)。
文摘Infancy and toddlerhood are critical phases of life,as the gut microbiota is established here,which influences current and future health.During this period,the microbiota was relatively less stable and highly responsive to environmental factors.Therefore,it is important to understand how dietary factors affect this complex stage of microbial assembly.The effect of feeding practices(breast milk/formula) on microbial colonization in early infancy has been actively studied;however,studies on the effect of diet on the gut microbiota during the complementary feeding period are sparse.The introduction of complementary foods provides abundant new dietary compounds for the gut microbiota,which induces a shift in gut microbiota and metabolism from milk-adapted toward a more mature and diverse adult-like community.Herein,we discuss the impact of dietary nutrients(carbohydrates,proteins,fats,vitamins,and minerals) on microbiome of infants and toddlers.Furthermore,this review summarizes the effects of complementary feeding patterns,specific foods(such as cereals;legumes and nuts;vegetables and fruits;meats;dairy products),food additives,and malnutrition(undernutrition or overnutrition) on gut microbiota of this populations.These findings might deepen our comprehension of the complex interactions between diets and the development and establishment of the gut microbiota.This may facilitate the tailoring of interventions aimed at promoting beneficial modifications within the gut microbial community.Furthermore,the insights gained could inform the design and implementation of safe and efficacious complementary feeding practices.
基金supported by the National Key R&D Program of China(No.2022YFB3205101)NSAF(No.U2230116)。
文摘To improve image quality under low illumination conditions,a novel low-light image enhancement method is proposed in this paper based on multi-illumination estimation and multi-scale fusion(MIMS).Firstly,the illumination is processed by contrast-limited adaptive histogram equalization(CLAHE),adaptive complementary gamma function(ACG),and adaptive detail preserving S-curve(ADPS),respectively,to obtain three components.Then,the fusion-relevant features,exposure,and color contrast are selected as the weight maps.Subsequently,these components and weight maps are fused through multi-scale to generate enhanced illumination.Finally,the enhanced images are obtained by multiplying the enhanced illumination and reflectance.Compared with existing approaches,this proposed method achieves an average increase of 0.81%and 2.89%in the structural similarity index measurement(SSIM)and peak signal-to-noise ratio(PSNR),and a decrease of 6.17%and 32.61%in the natural image quality evaluator(NIQE)and gradient magnitude similarity deviation(GMSD),respectively.
文摘Background:The use of complementary and alternative medicine(CAM)is common among individuals with underlying chronic illnesses.Objective:This systematic review and meta-analysis investigated the global prevalence and patterns of CAM use among individuals with chronic kidney disease(CKD).Search strategy:PubMed,Embase,and Cumulative Index to Nursing and Allied Health Literature Plus were searched from inception until 26th February 2024.Inclusion criteria:Original articles reporting the use of at least one type of CAM among individuals aged above 18 years old and at all stages of CKD or undergoing any form of kidney replacement therapy.Data extraction and analysis:Two independent reviewers performed the literature screening.The data were extracted from the included studies by one reviewer and cross-checked by another.Discrepancies were resolved by discussion and consensus among two reviewers.Primary information included prevalence of CAM use,types of CAM used,reasons for CAM use,factors associated with CAM use,and disclosure to healthcare providers.Meta-analyses were performed to determine the pooled prevalence of CAM use and non-disclosure of CAM using a random effect model.Results:Forty-one studies were included in this systematic review and meta-analysis.The pooled prevalence of CAM use was 43%(95%confidence interval:34%,51%),I2=99.46%.The reasons for CAM use included treatment of underlying comorbidities,complications or symptoms,maintenance of general health,and treatment of CKD.Nutritional approaches were the most common CAM modality,with 412different herbal and dietary supplements reported;psychological and physical approaches included massage therapy,relaxation techniques,and mind–body practices;and other complementary health approaches such as homeopathy,traditional Chinese medicine,and Ayurvedic medicine were also frequently reported.Factors associated with CAM use included sociodemographic characteristics such as older age,female gender,or higher income;disease or therapy factors such as not having diabetes,relying on hemodialysis,or poor adherence to medication;and patient or internal factors such as positive attitude towards CAM and perceived safety of CAM.About 66%(61%,72%)of CAM users did not disclose the use of CAM to their healthcare providers.Conclusion:CAM use is prevalent among individuals with CKD,and healthcare providers should communicate openly and effectively to emphasize the rational use of CAM to avoid potential harm.
基金financial support from the National Natural Science Foundation of China(NSFC 22172082)the Fundamental Research Funds for the Central Universities。
文摘Mild electrocatalytic nitrate reduction reaction(NO_(3)RR),driven by renewable electricity,is regarded as a desirable strategy for green ammonia synthesis and simultaneous removal of nitrogen-containing environmental pollutants.In view of different supply voltages from renewable energy sources,developing costeffective and efficient electrocatalysts with a wide operating potential window is very meaningful for practical application.However,currently reported catalysts usually need to introduce noble metals to synergistically achieve wide-potential selective ammonia synthesis from nitrate.In this work,we present for the first time a dual-transition-metal electrocatalyst(Fe_(3)C-CuO_(x)@NC,x=0,1)with wide-potential-adaptability for highly selective nitrate reduction to ammonia.Such Fe_(3)C-CuO_(x)@NC with spatially separated CuO_(x)and noblemetal-like Fe_(3)C nanoparticles encapsulated with nitrogen-doped graphitized carbon,exhibits outstanding performance in NO_(3)RR with desirable NH_(3)Faraday efficiency of more than 90%over a wide potential ranging from-0.2 V vs.RHE to-0.6 V vs.RHE,comparable to the reported noble metal catalysts.Different from common tandem catalysis,the wide-potential high ammonia selectivity of Fe_(3)C-CuO_(x)@NC is domina ntly ascribed to the complementary enhancement between CuO_(x)and Fe_(3)C,fully supported by results of experiments and density function theory calculations.CuO_(x)exhibit highly intrinsic nitrate reduction to nitrite to compensate for the slow potential determination step(^(*)NO_(3)→^(*)NO_(3)H)of Fe_(3)C,while Fe_(3)C,besides behaving like noble metals to supply adequate active hydrogens,has both good adsorption and reduction abilities for nitrite species to ammonia.Moreover,Fe_(3)C partially stabilizes active Cu^(0)/Cu^(+)sites,and the unique carbon-layer enca psulation structure effectively prevents the agglomeration and corrosion of metal nanoparticles during the electrocatalysis,thus maintaining good cyclic stability.The Zn-NO_(3)^(-)battery assembled with Fe_(3)C-CuO_(x)@NC can reach a high power density of 5.2 mW cm^(-2)at a potential of 1.0 V vs.Zn,with an NH_(3)Faraday efficiency of 92.4%at a current of 8.0 mA,proving its potential practical application.This advance provides unique insights into complementary catalysis mechanisms on multiple metal sites in NO_(3)RR,and offers a reference for the design of other transition metal electrocatalysts matching with renewable electricity.
基金Supported by National High Level Chinese Medicine Hospital Clinical Research Funding,No.DFGZRA-2024GJRC010The Fundamental Research Funds for the Central Universities,No.2024-JYB-JBZD-031.
文摘BACKGROUND Prediabetes is a high-risk precursor for diabetes development and is associated with increased psychological distress.Conventional pharmacological treatments for prediabetes have limitations,including adverse effects and poor patient compliance.Tuina’s abdominal vibration technique,a traditional non-pharmacological intervention,has shown promising results in glycemic regulation.However,its effects on psychological well-being remain largely unexplored.AIM To investigate efficacy of abdominal vibration at varying frequencies in Tuina for alleviating psychological and metabolic effects in prediabetes patients.METHODS A prospective cohort study(April 2025 to April 2026)at Dongfang Hospital of Beijing University of Chinese Medicine included 120 prediabetes patients.Participants were allocated to three groups based on vibration frequency:(1)Lowfrequency(400 times/minute,n=40);(2)Medium-frequency(500 times/minute,n=40);and(3)High-frequency(600 times/minute,n=40).All participants received 30-minute sessions three times weekly for 3 months,with follow-up at 6 months and 12 months.Primary outcomes included changes in depression(Beck Depression Inventory-Ⅱ),anxiety(State-Trait Anxiety Inventory),and stress(Perceived Stress Scale)levels.RESULTS After a 3-month intervention period,with follow-ups at 6 months and 12 months,patients in all three groups showed significant improvements in depression,anxiety,and stress scores compared to baseline(P<0.001).The high-frequency group demonstrated the most substantial psychological improvements(mean reduction in depression scores:9.2±2.3 points;anxiety:8.7±2.1 points;stress:10.4±2.5 points).These psychological improvements correlated significantly with reductions in insulin resistance(r=0.68,P<0.001).The high-frequency group also showed the most significant improvements in glycemic parameters,with mean reductions in fasting plasma glucose,2-hour postprandial glucose,and glycosylated hemoglobin concentrations of 0.92 mmol/L,1.87 mmol/L,and 0.51%,respectively.Correlation analysis revealed significant associations between improved psychological parameters and enhanced glycemic control.CONCLUSION Tuina’s abdominal vibration technique,especially at high frequency reduces depression,anxiety,and stress in prediabetes patients,correlating with enhanced glycemic control and insulin sensitivity,suggesting a bidirectional relationship between psychological and metabolic health.
文摘Gait,the unique pattern of how a person walks,has emerged as one of the most promising biometric features in modern intelligent sensing.Unlike fingerprints or facial characteristics,gait can be captured unobtrusively and at a distance,without requiring the subject’s awareness or cooperation.This makes it highly suitable for long-range surveillance,forensic investigation,and smart environments where contactless recognition is crucial.Traditional gait-recognition systems rely either on silhouettes,which capture the outer appearance of a person,or on skeletons,which describe the internal structure of human motion.Each modality provides only a partial understanding of gait.Silhouettes emphasize shape and contour but are easily distorted by clothing or carried objects;skeletons describe motion dynamics and limb coordination but lose discriminative details about body shape.This article presents the concept of Complementary Semantic Embedding(CSE),a unified framework that merges silhouette and skeleton information into a comprehensive semantic representation of human walking.By modeling the complementary nature of appearance and structure,the approach achieves more robust and accurate gait recognition even under challenging conditions.
基金Supported by Foundation of Science and Technology Department of Sichuan Province,China,No.23ZDYF0839Ya’an Philosophic and Social Science Research Plan,No.YAA20240035Ya'an Science and Technology Plan of Economic and Social Development(Health Field),Ya’an,China,No.2024-1.
文摘clear requirements for vigorously inheriting and developing traditional Chinese medicine,which should be an important part of the domestic healthcare system.Electroacupuncture,as a complementary therapy,has significant efficacy and potential in the field of enhanced recovery after surgery based on current available evidence.Despite some challenges,electroacupuncture is expected to play a greater role in healthcare practice through policy support and technological innovation in the future under the“Healthy China 2030”plan.
文摘Globally,the integration of traditional medicine and modern medicine has been recognized as a global health priority aimed at improving healthcare accessibility,cultural relevance,and therapeutic effectiveness.This review systematically examines the global landscape of traditional medicine-modern medicine integration by analyzing policy developments,regulatory frameworks,and clinical implementation models across various regions,including Asia,Africa,Europe,and the USA.The scope of the review encompasses five key domains:(1)global policy initiatives,(2)regulatory and institutional frameworks,(3)clinical integration models,(4)impacts and outcomes of integrative practices,and(5)challenges and barriers to implementation.Based on peer-reviewed literature and official health policy documents published between 2000 and 2025,the present review investigates how countries have operationalized clinical integration models combining traditional and complementary medicine.Although interest in traditional and complementary medicine has grown worldwide,persistent challenges,such as limited scientific validation,lack of standardization,and professional resistance,continue to hinder progress.This review concludes that successful and sustainable integration requires evidence-based clinical approaches,inclusive regulatory reforms,and coordinated policy strategies.Countries such as China,India,and Brazil have made significant advances,offering valuable models for future implementation worldwide.
文摘Under the current long-term electricity market mechanism,new energy and thermal power face issues such as deviation assessment and compression of generation space.The profitability of market players is limited.Simultaneously,the cooperation model among various energy sources will have a direct impact on the alliance’s revenue and the equity of income distribution within the alliance.Therefore,integrating new energy with thermal power units into an integrated multi-energy complementary system to participate in the long-term electricity market holds significant potential.To simulate and evaluate the benefits and internal distribution methods of a multi-energy complementary system participating in long-term market transactions,this paper first constructs a multi-energy complementary system integrated with new energy and thermal power generation units at the same connection point,and participates in the annual bilateral game as a unified market entity to obtain the revenue value under the annual bilateral market.Secondly,based on the entropy weight method,improvements are made to the traditional Shapley value distribution model,and an internal distribution model for multi-energy complementary systems with multiple participants is constructed.Finally,a Markov Decision Process(MDP)evaluation system is constructed for practical case verification.The research results show that the improved Shapley value distribution model achieves higher satisfaction,providing a reasonable allocation scheme for multi-energy complementary cooperation models.
基金supported in part by STI 2030-Major Projects under Grant 2022ZD0209200in part by Beijing Natural Science Foundation-Xiaomi Innovation Joint Fund(L233009)+4 种基金in part by National Natural Science Foundation of China under Grant No.62374099in part by the Tsinghua-Toyota Joint Research Fundin part by the Daikin Tsinghua Union Programin part by Independent Research Program of School of Integrated Circuits,Tsinghua UniversityThis work was also sponsored by CIE-Tencent Robotics X Rhino-Bird Focused Research Program.
文摘Emerging two-dimensional(2D)semiconductors are among the most promising materials for ultra-scaled transistors due to their intrinsic atomic-level thickness.As the stacking process advances,the complexity and cost of nanosheet field-effect transistors(NSFETs)and complementary FET(CFET)continue to rise.The 1 nm technology node is going to be based on Si-CFET process according to international roadmap for devices and systems(IRDS)(2022,https://irds.ieee.org/),but not publicly confirmed,indicating that more possibilities still exist.The miniaturization advantage of 2D semiconductors motivates us to explore their potential for reducing process costs while matching the performance of next-generation nodes in terms of area,power consumption and speed.In this study,a comprehensive framework is built.A set of MoS2 NSFETs were designed and fabricated to extract the key parameters and performances.And then for benchmarking,the sizes of 2D-NSFET are scaled to a extent that both of the Si-CFET and 2D-NSFET have the same average device footprint.Under these conditions,the frequency of ultra-scaled 2D-NSFET is found to improve by 36%at a fixed power consumption.This work verifies the feasibility of replacing silicon-based CFETs of 1 nm node with 2D-NSFETs and proposes a 2D technology solution for 1 nm nodes,i.e.,“2D eq 1 nm”nodes.At the same time,thanks to the lower characteristic length of 2D semiconductors,the miniaturized 2D-NSFET achieves a 28%frequency increase at a fixed power consumption.Further,developing a standard cell library,these devices obtain a similar trend in 16-bit RISC-V CPUs.This work quantifies and highlights the advantages of 2D semiconductors in advanced nodes,offering new possibilities for the application of 2D semiconductors in high-speed and low-power integrated circuits.
基金Supported by National Natural Science Foundation of China(Grant No.51875412)Top Discipline Plan of Shanghai Universities-ClassⅠ。
文摘Carbon fiber reinforced polymer(CFRP)are widely used in various fields because of their high strength,good toughness,and low density.However,owing to their unique forming process,some complex structures such as holes and grooves cannot be formed directly.Therefore,traditional machining procedures are also required.The drilling process is one of the most common machining methods for CFRP holes,but owing to the complex structure and difficulty in processing CFRP,the quality of the drilling process is often challenging to guarantee.Moreover,the hole-forming defects also have complex forms and lack uniform evaluation indexes.This study summarizes the common orifice defects in the process of CFRP drilling,establishes a comprehensive evaluation method of orifice defects by introducing the relevant theory of the fuzzy complementary judgment matrix,and experimentally verifies the accuracy and reliability of this method.Then,based on the experimental results,a non-linear cutting parameter optimization model is established,which effectively suppresses the orifice defects to ensure the accuracy of the hole size,roundness,and hole wall roughness.The hole-forming quality is subsequently improved.The hole quality evaluation method proposed in this study reduced the dimension of the evaluation index to ensure relevance and effectiveness and improved the convenience of quality inspection and parameter optimization in actual production.
基金Supported by the Coordination of Improvement of Higher Education Personnel(CAPES)and National Council for Scientific and Technological Development(CNPq),No.311427/2023-5.
文摘The international scientific literature presents still incipient results regarding the management of cancer symptom clusters by oncology nursing,especially in pediatric oncology.This is a promising field of investigation for clinical nurses and researchers,and when it is subsidized by medium-range theories,they co-rroborate the diagnoses and interventions of nursing in oncology,enhancing the science of nursing care.This minireview article aims to discuss the utilizing the hospital clowns as a complementary therapy,to enhance quality of life and reduce stress and fatigue in pediatric cancer patients.Overall,the evidence presented so far pointed out that complementary therapy might help improve the quality of life of pediatric cancer patients,and that complementary therapy usage should be part of a health comprehensive care model,delivering therapeutic approaches that might enhance the mind-body during a pediatric cancer patients’life span.The results of scientific investigations by nurses,particularly those linked to the basic sciences,play a critical role in advancing personalized care in pediatric integrative oncology.
文摘This editorial is based on the network pharmacology and in vivo study by Qin et al,which investigated the potential therapeutic mechanisms of Panax ginseng(P.ginseng)in ulcerative colitis.The key findings from the study included the identification of the targets of P.ginseng and ulcerative colitis,elucidation of mechanistic pathways,and in vivo validation of the pharmacological activity and therapeutic effect of panaxadiol,a key active component of P.ginseng.This editorial provides additional context regarding the evidence supporting the use of ginseng and other commonly used complementary therapies that clinicians may encounter.We also aim to highlight potential similarities between the mechanisms of popular complementary and conventional medical therapies.
文摘Intermittent fasting(IF)has emerged as a potential adjunctive strategy in cancer prevention,mitigation,and treatment.This narrative review synthesizes existing literature to explore the relationship between IF and cancer across 3 dimensions:prevention,mitigation,and treatment.We examine the underlying mechanisms by which IF may reduce cancer risk,including its effects on insulin-like growth factor 1 suppression,autophagy induction,and chronic inflammation reduction.Furthermore,we discuss IF’s potential to enhance the efficacy of conventional cancer therapies by sensitizing cancer cells,promoting apoptosis,and reducing treatmentrelated side effects.While promising,the evidence is still limited,and further research is required to elucidate the long-term impact and optimal implementation of IF in cancer care.This review aims to provide health care professionals and patients with a comprehensive understanding of the potential benefits and risks associated with IF as a complementary approach in the oncology setting.
