Objective: to explore the specific role of immunoglobulin and complement detection in the diagnosis of systemic lupus erythematosus (SLE). Methods: 50 patients with systemic lupus erythematosus admitted to our hospita...Objective: to explore the specific role of immunoglobulin and complement detection in the diagnosis of systemic lupus erythematosus (SLE). Methods: 50 patients with systemic lupus erythematosus admitted to our hospital in recent years were selected as the experimental group, and another 50 healthy subjects were selected as the control group, and the differences in body fluid indexes, immunoglobulin and complement detection of physical examination indexes between the two groups were analyzed. Results: the data related to IgG, IgM and IgA in the immune indexes of the control group were larger than that of the experimental group, while the data of complement C3 and C4 were relatively smaller, with P value less than 0.05. In the experimental group, there were more patients with positive autoantibodies and serum immunity, while there were no positive patients in the control group. The above experimental results were statistically significant. Conclusion: combined immunoglobulin and complement detection can improve the detection rate of systemic lupus erythematosus disease, provide important reference for the early diagnosis of SLE, help patients make scientific and accurate judgment in the later disease treatment, and promote its application in clinic, which is of great significance to improve the life safety and quality of life of patients.展开更多
文摘Objective: to explore the specific role of immunoglobulin and complement detection in the diagnosis of systemic lupus erythematosus (SLE). Methods: 50 patients with systemic lupus erythematosus admitted to our hospital in recent years were selected as the experimental group, and another 50 healthy subjects were selected as the control group, and the differences in body fluid indexes, immunoglobulin and complement detection of physical examination indexes between the two groups were analyzed. Results: the data related to IgG, IgM and IgA in the immune indexes of the control group were larger than that of the experimental group, while the data of complement C3 and C4 were relatively smaller, with P value less than 0.05. In the experimental group, there were more patients with positive autoantibodies and serum immunity, while there were no positive patients in the control group. The above experimental results were statistically significant. Conclusion: combined immunoglobulin and complement detection can improve the detection rate of systemic lupus erythematosus disease, provide important reference for the early diagnosis of SLE, help patients make scientific and accurate judgment in the later disease treatment, and promote its application in clinic, which is of great significance to improve the life safety and quality of life of patients.