We previously demonstrated that inhibiting neural stem cells necroptosis enhances functional recovery after spinal cord injury.While exosomes are recognized as playing a pivotal role in neural stem cells exocrine func...We previously demonstrated that inhibiting neural stem cells necroptosis enhances functional recovery after spinal cord injury.While exosomes are recognized as playing a pivotal role in neural stem cells exocrine function,their precise function in spinal cord injury remains unclear.To investigate the role of exosomes generated following neural stem cells necroptosis after spinal cord injury,we conducted singlecell RNA sequencing and validated that neural stem cells originate from ependymal cells and undergo necroptosis in response to spinal cord injury.Subsequently,we established an in vitro necroptosis model using neural stem cells isolated from embryonic mice aged 16-17 days and extracted exosomes.The results showed that necroptosis did not significantly impact the fundamental characteristics or number of exosomes.Transcriptome sequencing of exosomes in necroptosis group identified 108 differentially expressed messenger RNAs,104 long non-coding RNAs,720 circular RNAs,and 14 microRNAs compared with the control group.Construction of a competing endogenous RNA network identified the following hub genes:tuberous sclerosis 2(Tsc2),solute carrier family 16 member 3(Slc16a3),and forkhead box protein P1(Foxp1).Notably,a significant elevation in TSC2 expression was observed in spinal cord tissues following spinal cord injury.TSC2-positive cells were localized around SRY-box transcription factor 2-positive cells within the injury zone.Furthermore,in vitro analysis revealed increased TSC2 expression in exosomal receptor cells compared with other cells.Further assessment of cellular communication following spinal cord injury showed that Tsc2 was involved in ependymal cellular communication at 1 and 3 days post-injury through the epidermal growth factor and midkine signaling pathways.In addition,Slc16a3 participated in cellular communication in ependymal cells at 7 days post-injury via the vascular endothelial growth factor and macrophage migration inhibitory factor signaling pathways.Collectively,these findings confirm that exosomes derived from neural stem cells undergoing necroptosis play an important role in cellular communication after spinal cord injury and induce TSC2 upregulation in recipient cells.展开更多
The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration Compe...The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration Competing Interest statements,provided by authors,are included below.展开更多
The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration Compe...The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration Competing Interest statements,provided by authors,are included below.展开更多
The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration of Co...The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration of Competing Interest statements,provided by authors,are included below.展开更多
The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration of Co...The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration of Competing Interest statements,provided by authors,are included below.展开更多
The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration Compe...The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration Competing Interest statements,provided by authors,are included below.展开更多
Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Journal of Automation and Intelligence.The appropriate Declaration ...Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Journal of Automation and Intelligence.The appropriate Declaration of Competing Interest statements,provided by the Authors,are included below.1.“A survey on computationally efficient neural architecture search”[Journal of Automation and Intelligence,1(2022)100002].10.1016/j.jai.2022.100002。展开更多
BACKGROUND Children with critical acute abdominal conditions often undergo intestinal stoma surgery.AIM To explore the impact of a visual mobile terminal-based extended care model on caregiver competence for children ...BACKGROUND Children with critical acute abdominal conditions often undergo intestinal stoma surgery.AIM To explore the impact of a visual mobile terminal-based extended care model on caregiver competence for children with enterostomies.METHODS One hundred twenty children with enterostomies and their caregivers in a children's hospital in Beijing were divided into a control group and a study group.The control group(60 cases)received traditional telephone follow-up for continuity of care,while the study group(60 cases)used a visualization mobile terminal-based care model.The incidence of stoma-related complications,caregiver burden scale,and competence scores of children with stoma were compared between the two groups.RESULTS The primary caregiver burden score in the study group(37.22±3.17)was significantly lower than that in the control group(80.00±4.47),and the difference was statistically significant(P<0.05).Additionally,the caregiving ability score of the study group(172.08±3.49)was significantly higher than that of the control group(117.55±4.28;P<0.05).The total incidence of complications in the study group(11.7%,7/60)was significantly lower compared to the control group(33.3%,20/60;χ2=8.086,P=0.004).CONCLUSION The visual mobile terminal-based care model reduces caregiver burden,improves home care ability,lowers the incidence of complications and readmission rates,and supports successful second-stage reduction surgery for children with enterostomies.展开更多
BACKGROUND Brain-computer interface(BCI)technology is rapidly advancing in psychiatry.Informed consent competency(ICC)assessment among psychiatric patients is a pivotal concern in clinical research.AIM To analyze the ...BACKGROUND Brain-computer interface(BCI)technology is rapidly advancing in psychiatry.Informed consent competency(ICC)assessment among psychiatric patients is a pivotal concern in clinical research.AIM To analyze the assessment of ICC and form a framework with multi-dimensional elements involved in ICC of BCI clinical research among psychiatric disorders.METHODS A systematic review of studies regarding ICC assessments of BCI clinical research in patients with six kinds of psychiatric disorders was conducted.A systematic literature search was performed using PubMed,ScienceDirect,and Web of Science.Peer-reviewed articles and full-text studies were included in the analysis.There were no date restrictions,and all studies published up to February 27,2025,were included.RESULTS A total of 103 studies were selected for this review.Fifty-eight studies included ICC factors,and forty-five were classified in ICC related ethical issues of BCI research in six kinds of psychiatric disorders.Executive function impairment is widely recognized as the most significant factor impacting ICC,and processing speed deficits are observed in schizophrenia,mood disorders,and Alzheimer’s disease.Memory dysfunction,particularly episodic and working memory,contributes to compromised ICC.Five core ethical issues in BCI research should be addressed:BCI specificity,vulnerability,autonomy,dynamic ICC,comprehensiveness,and uncertainty.CONCLUSION A Five-Dimensional evaluative framework,including clinical,ethical,sociocultural,legal,and procedural dimensions,is constructed and proposed for future ICC research in BCI clinical research involving psychiatric disorders.展开更多
This study aims to investigate the current status of AI competencies among Chinese high school students using quantitative research methods.By integrating UNESCO’s AI Competency Framework for Students with China’s e...This study aims to investigate the current status of AI competencies among Chinese high school students using quantitative research methods.By integrating UNESCO’s AI Competency Framework for Students with China’s educational practices,a questionnaire was developed.Altogether,300 students from eight high schools joined the research.SPSS 26.0 was used for reliability and validity tests,exploratory factor analysis,and group difference analysis.The results show that the questionnaire has good reliability and validity(Cronbach’sα=0.974,KMO=0.912,Bartlett’s test of sphericity was significant with p<0.001,cumulative variance explained 72.0%).Besides,Chinese high school students’AI competencies exhibit a typical pattern of“strong in technology,weak in ethics,and insufficient in creativity”,with technical application ability(mean=3.7)significantly higher than ethical assessment(mean=3.0)and system design(mean=2.8).What’s more,students in the eastern region have significantly better overall competencies than those in the central and western regions(p<0.05),with the largest gap in the technical application dimension(mean difference=0.7)and the smallest gap in the ethical dimension(mean difference=0.3).The study recommends optimizing high school curricula by adding modules for ethical debates and interdisciplinary projects and promoting equitable distribution of educational resources.This research empirically supports global AI education standardization and offers a scientific basis for AI education policies and curriculum design in China’s high schools.展开更多
Electrochemical carbon dioxide reduction reaction(CO_(2)RR)converts CO_(2) into valuable chemicals by consuming renewable electricity at mild conditions,making it a promising approach to achieving carbon neutrality.Ho...Electrochemical carbon dioxide reduction reaction(CO_(2)RR)converts CO_(2) into valuable chemicals by consuming renewable electricity at mild conditions,making it a promising approach to achieving carbon neutrality.However,the reaction of CO_(2) with hydroxide ions to form carbonates leads to low carbon utilization and energy efficiency in near-neutral or alkaline CO_(2)RR.The high concentration of protons in acidic media can effectively mitigate carbonate formation and deposition,thereby significantly minimizing carbon loss and energy consumption.Unfortunately,hydrogen evolution reaction(HER)is more kinetically favorable than CO_(2)RR in acidic media.Herein,we comprehensively overview recent progress in acidic CO_(2)RR and propose two strategies derived from the competing reaction pathways of HER and CO_(2)RR:one focuses on regulating the H+mass transport,while the other aims to modulate the intrinsic kinetic activity of CO_(2)RR.The two strategies are designed to compete for the limited active sites on the catalyst surface,inhibit side reactions,and enhance the activity and selectivity of CO_(2)RR.The representative approaches include modulating the interface electric field,constructing a local alkaline environment,and regulating competing adsorption sites.Finally,we also review the technical challenges and future perspectives of acidic CO_(2)RR coupled with membrane electrode assemblies(MEAs).展开更多
BACKGROUND Given their responsibility for the well-being of individuals,nurses with advanced mental health literacy,along with strong holistic nursing competencies and professional self-efficacy,are better equipped to...BACKGROUND Given their responsibility for the well-being of individuals,nurses with advanced mental health literacy,along with strong holistic nursing competencies and professional self-efficacy,are better equipped to assess both the mental and physical health of their patients,leading to the provision of holistic nursing care.AIM To investigate the relationship between nurses’mental health literacy levels and their holistic nursing competencies,as well as their nursing professional selfefficacy.METHODS This study is cross-sectional,correlational research.The study sample consisted of a total of 261 volunteer nurses working in a training and research hospital and a state hospital between March 11,2024 and April 8,2024.Data were collected face to face with the“Descriptive Data Form”,“Mental Health Literacy Scale(MHLS)”,“Holistic Nursing Competence Scale(HNCS)”,and the“Nursing Profession Self-Efficacy Scale(NPSES)”.RESULTS The mean scale scores for the nurses were as follows:MHLS:95.88±11.67;HNCS:179.46±33.82;NPSES:64.79±11.24.A low-level positive correlation was found between the total scores of the MHLS,HNCS,and NPSES,and a moderate-level positive correlation was observed between the total scores of the HNCS and NPSES.These correlations were statistically significant(P<0.05).CONCLUSION It is recommended that initiatives be undertaken to enhance the mental health literacy and holistic nursing competencies of nurses and that similar studies be conducted with nurses in different institutions and with a larger number of nurses.展开更多
The advent of artificial intelligence(AI)in recent years has brought about transformative changes across various sectors,including healthcare.In nursing practice,education,and research,AI has the potential to revoluti...The advent of artificial intelligence(AI)in recent years has brought about transformative changes across various sectors,including healthcare.In nursing practice,education,and research,AI has the potential to revolutionize traditional methodologies,enhance learning experiences,and improve patient outcomes.Integrating AI tools and techniques can provide clinicians with smarter clinical solutions and nursing students with more robust and interactive learning environments,while also advancing research capabilities in the field.Despite the promising prospects,the incorporation of AI into nursing practice,education,and research presents several challenges.Firstly,there is a concern about the potential displacement of human roles in nursing due to automation,which may affect the human-centric nature of nursing care.Secondly,there are issues related to the lag in AI competency among nurses.Many current nursing curricula do not include comprehensive AI training,leading to a lack of preparedness in utilizing these technologies effectively.Lastly,the ethical implications of AI in healthcare,such as data privacy,patient consent,and the potential for biased algorithms,need to be meticulously addressed.To harness the full potential of AI in nursing practice,education,and research,several strategic actions including reinvesting in humanistic practice,revising core competencies and curriculum,and developing new ethical guidelines.展开更多
Objective: The importance of culture in nursing lies in its influence on patients’ health perceptions, behaviors, and responses to care. Despite the challenges posed by the complexity of studying culture, there remai...Objective: The importance of culture in nursing lies in its influence on patients’ health perceptions, behaviors, and responses to care. Despite the challenges posed by the complexity of studying culture, there remains a critical need to develop cultural competence in nursing. This study investigated how nursing students in rural Indonesia enhance their cultural competence through education and practice. Methods: This study employed a qualitative descriptive phenomenological approach. It conducted face-to-face interviews with 32 students across 6 regions, selected purposively. Thematic analysis was employed to evaluate the results. Results: Five themes emerge in this research: perceptions of cultural competence, learning cultural competence in the classroom, practical experience, learning expectations related to cultural competence, and cultural learning barriers. Conclusions: Enhancing cultural competence necessitates enriched curricula, adept clinical mentors, and continual student evaluation. This iterative assessment informs tailored strategies for nurturing cultural proficiency.展开更多
In recent decades,researches on teacher’s competence has shifted from a singular macro perspective to a systematic micro view.This article explores the multifaceted domain of teachers’competence in China by utilizin...In recent decades,researches on teacher’s competence has shifted from a singular macro perspective to a systematic micro view.This article explores the multifaceted domain of teachers’competence in China by utilizing textual analysis.It critically analyzes the research content pertaining to the connotation,structural components,and empirical applications of teachers’multicultural abilities.It summarizes various definitions,structures,and empirical studies in the context of China and proposes some directions of future research.展开更多
Background:The Teaching Personal and Social Responsibility(TPSR)model in physical education(PE)has been shown to promote Social and emotional competence(SEC).However,the underlying mechanisms through which TPSR enhanc...Background:The Teaching Personal and Social Responsibility(TPSR)model in physical education(PE)has been shown to promote Social and emotional competence(SEC).However,the underlying mechanisms through which TPSR enhances SEC,particularly in university students within the Chinese context,remain unclear.This study aims to explore the effects of TPSR and the mediating roles of self-efficacy and grit in improving SEC.Methods:71 Chinese university students were in the TPSR group,and 39 in the Traditional Teaching Model(TTM)control group,assessed before and after a 14-week intervention.The Adapted Social and Emotional Competence Scale(ASECS),General Self-Efficacy Scale(GSES),and Short Grit Scale(SGS)were used for measurement.A mixed-design ANOVA assessed TPSR’s effects,with post-hoc t-tests for pre-post differences and mediation analysis for underlying mechanisms.Results:The mixed-design ANOVA revealed a significant interaction between time and intervention on SEC.The TPSR group showed significant improvement from pre-test to post-test(t(70)=−2.63,p=0.011,Cohen’s d=−0.31),whereas the TTM control group did not(t(38)=1.40,p=0.170,Cohen’s d=0.22).The TPSR group also showed a significant increase in self-efficacy(t(70)=−3.67,p<0.001,Cohen’s d=−0.44),while no change was observed in the TTM group(t(38)=0.62,p=0.540,Cohen’s d=0.10).No significant effects were found for grit(F=0.342,p=0.560).Mediation analysis confirmed that self-efficacy significantly mediated the effects of the TPSR intervention on SEC(95%CI:0.0277 to 0.2897).Conclusion:The TPSR intervention led to significant improvements in university students’SEC and self-efficacy,with no significant changes observed in grit.Self-efficacy served as a mediator in the relationship between the intervention and SEC.展开更多
This paper is about the transformation process of theoretical frameworks used in educational research on teaching evolution. To this end, some authors' claims, findings and suggestions offered via particular studi...This paper is about the transformation process of theoretical frameworks used in educational research on teaching evolution. To this end, some authors' claims, findings and suggestions offered via particular studies are evaluated. While the evaluated authors have represented secularism as a barrier to teaching evolution in the United States, they have also offered pedagogically theistic or agnostic evolution as the best choice for the reconciliation of religion and evolution. This paper is particularly concerned with one of the explanatory theoretical frameworks—religious cultural competence in evolution education(ReCCEE), which is derived from the cultural competence framework—although others are visited as well. Even though the schools or authors who have applied ReCCEE do not directly reference constructivism, their studies are built upon constructivist pedagogy and epistemological idealism. They often have problematic issues such as obscurantism, ad hominem attacks, cherry-picking and an ill-formed appeal to authority. Besides, these papers present biased or uncritical views and ill-informed definitions of some terms, such as secularism and agnosticism.展开更多
Objectives:The study aimed to survey the current situation and explore the factors that influence the ability of palliative care practice among oncology nurses.Methods:A multicenter cross-sectional study was conducted...Objectives:The study aimed to survey the current situation and explore the factors that influence the ability of palliative care practice among oncology nurses.Methods:A multicenter cross-sectional study was conducted using stratified random sampling to select 26 tertiary hospitals’oncology departments in Hubei Province,China.A total of 1,198 nurses were included and finished the questionnaire consisting of social demographic characteristics,Palliative Care Self-Report Practice Scale(PCPS),End-of-life Professional Caregiver Survey(EPCS),and Self-Perceived Pain Assessment Knowledge and Confidence Scale(Self-PAC)through the online platform.Data were analyzed using t-test,one-way ANOVA,Pearson correlation analysis,and multiple linear regression analysis in SPSS 26.0.Results:The total score for PCPS was 67.17±12.57,the three dimensions’scores were:physical symptom care(32.50±6.10),spiritual and psychological care(23.35±4.97),communication(11.58±2.48).There are significant positive correlations between the palliative care practice ability and core competence(r=0.77,P<0.01),as well as pain assessment ability(r=0.56,P<0.01).Multiple regression analysis identified female,with high education background(bachelor’s degree and master’s degree or above),interest in palliative care,pain assessment ability,and core competence were positive predictors of palliative care practice ability(Adjusted R^(2)=0.668,P<0.05).Conclusions:The overall ability of the oncology nurses to practice palliative care was relatively high,but the palliative nurses reported suboptimal performance in the communication dimension of palliative nursing practice ability.To comprehensively improve oncology nurses’palliative care practice ability,managers must consider the gender structure,educational background,enthusiasm for palliative care work,core competence,and pain assessment ability.展开更多
Ultrasound has long been an essential tool in nephrology,traditionally used for procedures like vascular access and kidney biopsies.Point-of-care ultrasonography(POCUS),a rapidly evolving bedside technology,is now gai...Ultrasound has long been an essential tool in nephrology,traditionally used for procedures like vascular access and kidney biopsies.Point-of-care ultrasonography(POCUS),a rapidly evolving bedside technology,is now gaining momentum in nephrology by providing real-time imaging to enhance physical examination findings.Unlike comprehensive radiology-performed ultrasound,POCUS focuses on specific clinical questions,providing immediate and actionable insights.This narrative review examines the philosophy behind POCUS,its expanding applications in nephrology,and its impact on patient care,including its role in diagnosing obstructive uropathy,guiding fluid management,and evaluating hemodynamics in cardiorenal syndrome.Additionally,the review addresses barriers to widespread adoption,such as the need for structured training,competency validation,and interdisciplinary cooperation.By integrating POCUS into routine practice,nephrologists can refine diagnostic accuracy,improve patient outcomes,and strengthen the role of bedside medicine.展开更多
With the rise of data-intensive research,data literacy has become a critical capability for improving scientific data quality and achieving artificial intelligence(AI)readiness.In the biomedical domain,data are charac...With the rise of data-intensive research,data literacy has become a critical capability for improving scientific data quality and achieving artificial intelligence(AI)readiness.In the biomedical domain,data are characterized by high complexity and privacy sensitivity,calling for robust and systematic data management skills.This paper reviews current trends in scientific data governance and the evolving policy landscape,highlighting persistent challenges such as inconsistent standards,semantic misalignment,and limited awareness of compliance.These issues are largely rooted in the lack of structured training and practical support for researchers.In response,this study builds on existing data literacy frameworks and integrates the specific demands of biomedical research to propose a comprehensive,lifecycle-oriented data literacy competency model with an emphasis on ethics and regulatory awareness.Furthermore,it outlines a tiered training strategy tailored to different research stages—undergraduate,graduate,and professional,offering theoretical foundations and practical pathways for universities and research institutions to advance data literacy education.展开更多
基金supported by the National Natural Science Foundation of China,No.81801907(to NC)Shenzhen Key Laboratory of Bone Tissue Repair and Translational Research,No.ZDSYS20230626091402006(to NC)+2 种基金Sanming Project of Medicine in Shenzhen,No.SZSM201911002(to SL)Foundation of Shenzhen Committee for Science and Technology Innovation,Nos.JCYJ20230807110310021(to NC),JCYJ20230807110259002(to JL)Science and Technology Program of Guangzhou,No.2024A04J4716(to TL)。
文摘We previously demonstrated that inhibiting neural stem cells necroptosis enhances functional recovery after spinal cord injury.While exosomes are recognized as playing a pivotal role in neural stem cells exocrine function,their precise function in spinal cord injury remains unclear.To investigate the role of exosomes generated following neural stem cells necroptosis after spinal cord injury,we conducted singlecell RNA sequencing and validated that neural stem cells originate from ependymal cells and undergo necroptosis in response to spinal cord injury.Subsequently,we established an in vitro necroptosis model using neural stem cells isolated from embryonic mice aged 16-17 days and extracted exosomes.The results showed that necroptosis did not significantly impact the fundamental characteristics or number of exosomes.Transcriptome sequencing of exosomes in necroptosis group identified 108 differentially expressed messenger RNAs,104 long non-coding RNAs,720 circular RNAs,and 14 microRNAs compared with the control group.Construction of a competing endogenous RNA network identified the following hub genes:tuberous sclerosis 2(Tsc2),solute carrier family 16 member 3(Slc16a3),and forkhead box protein P1(Foxp1).Notably,a significant elevation in TSC2 expression was observed in spinal cord tissues following spinal cord injury.TSC2-positive cells were localized around SRY-box transcription factor 2-positive cells within the injury zone.Furthermore,in vitro analysis revealed increased TSC2 expression in exosomal receptor cells compared with other cells.Further assessment of cellular communication following spinal cord injury showed that Tsc2 was involved in ependymal cellular communication at 1 and 3 days post-injury through the epidermal growth factor and midkine signaling pathways.In addition,Slc16a3 participated in cellular communication in ependymal cells at 7 days post-injury via the vascular endothelial growth factor and macrophage migration inhibitory factor signaling pathways.Collectively,these findings confirm that exosomes derived from neural stem cells undergoing necroptosis play an important role in cellular communication after spinal cord injury and induce TSC2 upregulation in recipient cells.
文摘The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration Competing Interest statements,provided by authors,are included below.
文摘The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration Competing Interest statements,provided by authors,are included below.
文摘The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration of Competing Interest statements,provided by authors,are included below.
文摘The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration of Competing Interest statements,provided by authors,are included below.
文摘The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration Competing Interest statements,provided by authors,are included below.
文摘Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Journal of Automation and Intelligence.The appropriate Declaration of Competing Interest statements,provided by the Authors,are included below.1.“A survey on computationally efficient neural architecture search”[Journal of Automation and Intelligence,1(2022)100002].10.1016/j.jai.2022.100002。
基金Supported by Project of the Health Bureau of the Logistics and Security Department of the Central Military Commission,No.145BHQ090003076XMilitary Family Planning Special Fund,No.21JSZ18.
文摘BACKGROUND Children with critical acute abdominal conditions often undergo intestinal stoma surgery.AIM To explore the impact of a visual mobile terminal-based extended care model on caregiver competence for children with enterostomies.METHODS One hundred twenty children with enterostomies and their caregivers in a children's hospital in Beijing were divided into a control group and a study group.The control group(60 cases)received traditional telephone follow-up for continuity of care,while the study group(60 cases)used a visualization mobile terminal-based care model.The incidence of stoma-related complications,caregiver burden scale,and competence scores of children with stoma were compared between the two groups.RESULTS The primary caregiver burden score in the study group(37.22±3.17)was significantly lower than that in the control group(80.00±4.47),and the difference was statistically significant(P<0.05).Additionally,the caregiving ability score of the study group(172.08±3.49)was significantly higher than that of the control group(117.55±4.28;P<0.05).The total incidence of complications in the study group(11.7%,7/60)was significantly lower compared to the control group(33.3%,20/60;χ2=8.086,P=0.004).CONCLUSION The visual mobile terminal-based care model reduces caregiver burden,improves home care ability,lowers the incidence of complications and readmission rates,and supports successful second-stage reduction surgery for children with enterostomies.
基金Supported by the Ministry of Science and Technology of the People's Republic of China(2021ZD0201900)Project 5,No.2021ZD0201905Capital’s Funds for Health Improvement and Research,No.CFH 2022-2-4115.
文摘BACKGROUND Brain-computer interface(BCI)technology is rapidly advancing in psychiatry.Informed consent competency(ICC)assessment among psychiatric patients is a pivotal concern in clinical research.AIM To analyze the assessment of ICC and form a framework with multi-dimensional elements involved in ICC of BCI clinical research among psychiatric disorders.METHODS A systematic review of studies regarding ICC assessments of BCI clinical research in patients with six kinds of psychiatric disorders was conducted.A systematic literature search was performed using PubMed,ScienceDirect,and Web of Science.Peer-reviewed articles and full-text studies were included in the analysis.There were no date restrictions,and all studies published up to February 27,2025,were included.RESULTS A total of 103 studies were selected for this review.Fifty-eight studies included ICC factors,and forty-five were classified in ICC related ethical issues of BCI research in six kinds of psychiatric disorders.Executive function impairment is widely recognized as the most significant factor impacting ICC,and processing speed deficits are observed in schizophrenia,mood disorders,and Alzheimer’s disease.Memory dysfunction,particularly episodic and working memory,contributes to compromised ICC.Five core ethical issues in BCI research should be addressed:BCI specificity,vulnerability,autonomy,dynamic ICC,comprehensiveness,and uncertainty.CONCLUSION A Five-Dimensional evaluative framework,including clinical,ethical,sociocultural,legal,and procedural dimensions,is constructed and proposed for future ICC research in BCI clinical research involving psychiatric disorders.
基金supported by Research Project on Humanities and Social Sciences in Higher Education Institutions of Guizhou Provincial Department of Education(No.24RWZX060).
文摘This study aims to investigate the current status of AI competencies among Chinese high school students using quantitative research methods.By integrating UNESCO’s AI Competency Framework for Students with China’s educational practices,a questionnaire was developed.Altogether,300 students from eight high schools joined the research.SPSS 26.0 was used for reliability and validity tests,exploratory factor analysis,and group difference analysis.The results show that the questionnaire has good reliability and validity(Cronbach’sα=0.974,KMO=0.912,Bartlett’s test of sphericity was significant with p<0.001,cumulative variance explained 72.0%).Besides,Chinese high school students’AI competencies exhibit a typical pattern of“strong in technology,weak in ethics,and insufficient in creativity”,with technical application ability(mean=3.7)significantly higher than ethical assessment(mean=3.0)and system design(mean=2.8).What’s more,students in the eastern region have significantly better overall competencies than those in the central and western regions(p<0.05),with the largest gap in the technical application dimension(mean difference=0.7)and the smallest gap in the ethical dimension(mean difference=0.3).The study recommends optimizing high school curricula by adding modules for ethical debates and interdisciplinary projects and promoting equitable distribution of educational resources.This research empirically supports global AI education standardization and offers a scientific basis for AI education policies and curriculum design in China’s high schools.
基金supported by the National Natural Science Foundation of China(52301259 and 22208019)the Research Fund Program for Young Scholars of Beijing Institute of Technology。
文摘Electrochemical carbon dioxide reduction reaction(CO_(2)RR)converts CO_(2) into valuable chemicals by consuming renewable electricity at mild conditions,making it a promising approach to achieving carbon neutrality.However,the reaction of CO_(2) with hydroxide ions to form carbonates leads to low carbon utilization and energy efficiency in near-neutral or alkaline CO_(2)RR.The high concentration of protons in acidic media can effectively mitigate carbonate formation and deposition,thereby significantly minimizing carbon loss and energy consumption.Unfortunately,hydrogen evolution reaction(HER)is more kinetically favorable than CO_(2)RR in acidic media.Herein,we comprehensively overview recent progress in acidic CO_(2)RR and propose two strategies derived from the competing reaction pathways of HER and CO_(2)RR:one focuses on regulating the H+mass transport,while the other aims to modulate the intrinsic kinetic activity of CO_(2)RR.The two strategies are designed to compete for the limited active sites on the catalyst surface,inhibit side reactions,and enhance the activity and selectivity of CO_(2)RR.The representative approaches include modulating the interface electric field,constructing a local alkaline environment,and regulating competing adsorption sites.Finally,we also review the technical challenges and future perspectives of acidic CO_(2)RR coupled with membrane electrode assemblies(MEAs).
文摘BACKGROUND Given their responsibility for the well-being of individuals,nurses with advanced mental health literacy,along with strong holistic nursing competencies and professional self-efficacy,are better equipped to assess both the mental and physical health of their patients,leading to the provision of holistic nursing care.AIM To investigate the relationship between nurses’mental health literacy levels and their holistic nursing competencies,as well as their nursing professional selfefficacy.METHODS This study is cross-sectional,correlational research.The study sample consisted of a total of 261 volunteer nurses working in a training and research hospital and a state hospital between March 11,2024 and April 8,2024.Data were collected face to face with the“Descriptive Data Form”,“Mental Health Literacy Scale(MHLS)”,“Holistic Nursing Competence Scale(HNCS)”,and the“Nursing Profession Self-Efficacy Scale(NPSES)”.RESULTS The mean scale scores for the nurses were as follows:MHLS:95.88±11.67;HNCS:179.46±33.82;NPSES:64.79±11.24.A low-level positive correlation was found between the total scores of the MHLS,HNCS,and NPSES,and a moderate-level positive correlation was observed between the total scores of the HNCS and NPSES.These correlations were statistically significant(P<0.05).CONCLUSION It is recommended that initiatives be undertaken to enhance the mental health literacy and holistic nursing competencies of nurses and that similar studies be conducted with nurses in different institutions and with a larger number of nurses.
文摘The advent of artificial intelligence(AI)in recent years has brought about transformative changes across various sectors,including healthcare.In nursing practice,education,and research,AI has the potential to revolutionize traditional methodologies,enhance learning experiences,and improve patient outcomes.Integrating AI tools and techniques can provide clinicians with smarter clinical solutions and nursing students with more robust and interactive learning environments,while also advancing research capabilities in the field.Despite the promising prospects,the incorporation of AI into nursing practice,education,and research presents several challenges.Firstly,there is a concern about the potential displacement of human roles in nursing due to automation,which may affect the human-centric nature of nursing care.Secondly,there are issues related to the lag in AI competency among nurses.Many current nursing curricula do not include comprehensive AI training,leading to a lack of preparedness in utilizing these technologies effectively.Lastly,the ethical implications of AI in healthcare,such as data privacy,patient consent,and the potential for biased algorithms,need to be meticulously addressed.To harness the full potential of AI in nursing practice,education,and research,several strategic actions including reinvesting in humanistic practice,revising core competencies and curriculum,and developing new ethical guidelines.
基金supported by an internal grant from Universitas Citra Bangsa(Number 6/VI/LP3M/UCB/22).
文摘Objective: The importance of culture in nursing lies in its influence on patients’ health perceptions, behaviors, and responses to care. Despite the challenges posed by the complexity of studying culture, there remains a critical need to develop cultural competence in nursing. This study investigated how nursing students in rural Indonesia enhance their cultural competence through education and practice. Methods: This study employed a qualitative descriptive phenomenological approach. It conducted face-to-face interviews with 32 students across 6 regions, selected purposively. Thematic analysis was employed to evaluate the results. Results: Five themes emerge in this research: perceptions of cultural competence, learning cultural competence in the classroom, practical experience, learning expectations related to cultural competence, and cultural learning barriers. Conclusions: Enhancing cultural competence necessitates enriched curricula, adept clinical mentors, and continual student evaluation. This iterative assessment informs tailored strategies for nurturing cultural proficiency.
基金supported by grants from Social Science Fund of Xinjiang Autonomous Region(2023VZJ017)Humanities and Social Science Fund of the Education Ministry(23YJA740050)+1 种基金Sino-Foreign Cooperation Project of the Center for Language Education and Cooperation(22YH41ZW)Think Tank Key Project of Xinjiang Normal University(ZK2024B02).
文摘In recent decades,researches on teacher’s competence has shifted from a singular macro perspective to a systematic micro view.This article explores the multifaceted domain of teachers’competence in China by utilizing textual analysis.It critically analyzes the research content pertaining to the connotation,structural components,and empirical applications of teachers’multicultural abilities.It summarizes various definitions,structures,and empirical studies in the context of China and proposes some directions of future research.
基金funded by the 2023 Scientific Research Platforms and Projects of Guangdong Provincial Education Department,Grant Number 2023WQNCX079.
文摘Background:The Teaching Personal and Social Responsibility(TPSR)model in physical education(PE)has been shown to promote Social and emotional competence(SEC).However,the underlying mechanisms through which TPSR enhances SEC,particularly in university students within the Chinese context,remain unclear.This study aims to explore the effects of TPSR and the mediating roles of self-efficacy and grit in improving SEC.Methods:71 Chinese university students were in the TPSR group,and 39 in the Traditional Teaching Model(TTM)control group,assessed before and after a 14-week intervention.The Adapted Social and Emotional Competence Scale(ASECS),General Self-Efficacy Scale(GSES),and Short Grit Scale(SGS)were used for measurement.A mixed-design ANOVA assessed TPSR’s effects,with post-hoc t-tests for pre-post differences and mediation analysis for underlying mechanisms.Results:The mixed-design ANOVA revealed a significant interaction between time and intervention on SEC.The TPSR group showed significant improvement from pre-test to post-test(t(70)=−2.63,p=0.011,Cohen’s d=−0.31),whereas the TTM control group did not(t(38)=1.40,p=0.170,Cohen’s d=0.22).The TPSR group also showed a significant increase in self-efficacy(t(70)=−3.67,p<0.001,Cohen’s d=−0.44),while no change was observed in the TTM group(t(38)=0.62,p=0.540,Cohen’s d=0.10).No significant effects were found for grit(F=0.342,p=0.560).Mediation analysis confirmed that self-efficacy significantly mediated the effects of the TPSR intervention on SEC(95%CI:0.0277 to 0.2897).Conclusion:The TPSR intervention led to significant improvements in university students’SEC and self-efficacy,with no significant changes observed in grit.Self-efficacy served as a mediator in the relationship between the intervention and SEC.
文摘This paper is about the transformation process of theoretical frameworks used in educational research on teaching evolution. To this end, some authors' claims, findings and suggestions offered via particular studies are evaluated. While the evaluated authors have represented secularism as a barrier to teaching evolution in the United States, they have also offered pedagogically theistic or agnostic evolution as the best choice for the reconciliation of religion and evolution. This paper is particularly concerned with one of the explanatory theoretical frameworks—religious cultural competence in evolution education(ReCCEE), which is derived from the cultural competence framework—although others are visited as well. Even though the schools or authors who have applied ReCCEE do not directly reference constructivism, their studies are built upon constructivist pedagogy and epistemological idealism. They often have problematic issues such as obscurantism, ad hominem attacks, cherry-picking and an ill-formed appeal to authority. Besides, these papers present biased or uncritical views and ill-informed definitions of some terms, such as secularism and agnosticism.
基金supported by the Philosophy and Social Science Research Youth Project of the Hubei Department of Education in 2022(22Q148).
文摘Objectives:The study aimed to survey the current situation and explore the factors that influence the ability of palliative care practice among oncology nurses.Methods:A multicenter cross-sectional study was conducted using stratified random sampling to select 26 tertiary hospitals’oncology departments in Hubei Province,China.A total of 1,198 nurses were included and finished the questionnaire consisting of social demographic characteristics,Palliative Care Self-Report Practice Scale(PCPS),End-of-life Professional Caregiver Survey(EPCS),and Self-Perceived Pain Assessment Knowledge and Confidence Scale(Self-PAC)through the online platform.Data were analyzed using t-test,one-way ANOVA,Pearson correlation analysis,and multiple linear regression analysis in SPSS 26.0.Results:The total score for PCPS was 67.17±12.57,the three dimensions’scores were:physical symptom care(32.50±6.10),spiritual and psychological care(23.35±4.97),communication(11.58±2.48).There are significant positive correlations between the palliative care practice ability and core competence(r=0.77,P<0.01),as well as pain assessment ability(r=0.56,P<0.01).Multiple regression analysis identified female,with high education background(bachelor’s degree and master’s degree or above),interest in palliative care,pain assessment ability,and core competence were positive predictors of palliative care practice ability(Adjusted R^(2)=0.668,P<0.05).Conclusions:The overall ability of the oncology nurses to practice palliative care was relatively high,but the palliative nurses reported suboptimal performance in the communication dimension of palliative nursing practice ability.To comprehensively improve oncology nurses’palliative care practice ability,managers must consider the gender structure,educational background,enthusiasm for palliative care work,core competence,and pain assessment ability.
文摘Ultrasound has long been an essential tool in nephrology,traditionally used for procedures like vascular access and kidney biopsies.Point-of-care ultrasonography(POCUS),a rapidly evolving bedside technology,is now gaining momentum in nephrology by providing real-time imaging to enhance physical examination findings.Unlike comprehensive radiology-performed ultrasound,POCUS focuses on specific clinical questions,providing immediate and actionable insights.This narrative review examines the philosophy behind POCUS,its expanding applications in nephrology,and its impact on patient care,including its role in diagnosing obstructive uropathy,guiding fluid management,and evaluating hemodynamics in cardiorenal syndrome.Additionally,the review addresses barriers to widespread adoption,such as the need for structured training,competency validation,and interdisciplinary cooperation.By integrating POCUS into routine practice,nephrologists can refine diagnostic accuracy,improve patient outcomes,and strengthen the role of bedside medicine.
文摘With the rise of data-intensive research,data literacy has become a critical capability for improving scientific data quality and achieving artificial intelligence(AI)readiness.In the biomedical domain,data are characterized by high complexity and privacy sensitivity,calling for robust and systematic data management skills.This paper reviews current trends in scientific data governance and the evolving policy landscape,highlighting persistent challenges such as inconsistent standards,semantic misalignment,and limited awareness of compliance.These issues are largely rooted in the lack of structured training and practical support for researchers.In response,this study builds on existing data literacy frameworks and integrates the specific demands of biomedical research to propose a comprehensive,lifecycle-oriented data literacy competency model with an emphasis on ethics and regulatory awareness.Furthermore,it outlines a tiered training strategy tailored to different research stages—undergraduate,graduate,and professional,offering theoretical foundations and practical pathways for universities and research institutions to advance data literacy education.
