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Design of a high-voltage radiation-tolerant driver with a novel comparator and drain-surrounding-source structure 被引量:1
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作者 Wei Huang Hong-Xia Liu Xing-Guo Gao 《Nuclear Science and Techniques》 2025年第7期34-43,共10页
This article introduces a novel 20 V radiation-hardened high-voltage metal-oxide-semiconductor field-effect transistor(MOSFET)driver with an optimized input circuit and a drain-surrounding-source(DSS)structure.The inp... This article introduces a novel 20 V radiation-hardened high-voltage metal-oxide-semiconductor field-effect transistor(MOSFET)driver with an optimized input circuit and a drain-surrounding-source(DSS)structure.The input circuit of a conventional inverter consists of a thick-gate-oxide n-type MOSFET(NMOS).These conventional drivers can tolerate a total ionizing dose(TID)of up to 100 krad(Si).In contrast,the proposed comparator input circuit uses both a thick-gate-oxide p-type MOSFET(PMOS)and thin-gate-oxide NMOS to offer a high input voltage and higher TID tolerance.Because the thick-gate-oxide PMOS and thin-gate-oxide NMOS collectively provide better TID tolerance than the thick-gate-oxide NMOS,the circuit exhibits enhanced TID tolerance of>300 krad(Si).Simulations and experimental date indicate that the DSS structure reduces the probability of unwanted parasitic bipolar junction transistor activation,yielding a better single-event effect tolerance of over 81.8 MeVcm^(2)mg^(-1).The innovative strategy proposed in this study involves circuit and layout design optimization,and does not require any specialized process flow.Hence,the proposed circuit can be manufactured using common commercial 0.35μm BCD processes. 展开更多
关键词 Total ionizing dose(TID) Single-event burnout(SEB) High-voltage driver comparator input unit Drain-surrounding-source ring structure
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A CMOS Dynamic Comparator for Pipelined ADCs with Improved Speed/Power Ratio 被引量:6
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作者 刘珂 杨海钢 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2008年第1期75-81,共7页
This paper presents a fully-differential CMOS dynamic comparator for use in high-speed pipelined ADCs with low stage resolution. Because the architecture is based on the coupled current sources and differential input ... This paper presents a fully-differential CMOS dynamic comparator for use in high-speed pipelined ADCs with low stage resolution. Because the architecture is based on the coupled current sources and differential input pairs, this comparator's threshold voltage can be adjusted to a desired level. Compared with traditional comparators, this one shows significant improvement in area,power,and speed. Fabricated in 0.35μm CMOS technology,it occupies only 30μm × 70μm. Simulation and measurement results indicate the comparator has a sampling frequency up to 1GHz with 2Vpp differential input signal range and only 181μW power consumption under a 3.3V supply. The speed/power ratio reaches up to 5524GS/J. 展开更多
关键词 CMOS comparator ADC
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Brain structural plasticity in large-brained mammals:Not only narrowing roads
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作者 Marco Ghibaudi Alessandro Zanone Luca Bonfanti 《Neural Regeneration Research》 2026年第5期1669-1680,共12页
The capacity of the central nervous system for structural plasticity and regeneration is commonly believed to show a decreasing progression from“small and simple”brains to the larger,more complex brains of mammals.H... The capacity of the central nervous system for structural plasticity and regeneration is commonly believed to show a decreasing progression from“small and simple”brains to the larger,more complex brains of mammals.However,recent findings revealed that some forms of neural plasticity can show a reverse trend.Although plasticity is a well-preserved,transversal feature across the animal world,a variety of cell populations and mechanisms seem to have evolved to enable structural modifications to take place in widely different brains,likely as adaptations to selective pressures.Increasing evidence now indicates that a trade-off has occurred between regenerative(mostly stem cell–driven)plasticity and developmental(mostly juvenile)remodeling,with the latter primarily aimed not at brain repair but rather at“sculpting”the neural circuits based on experience.In particular,an evolutionary trade-off has occurred between neurogenic processes intended to support the possibility of recruiting new neurons throughout life and the different ways of obtaining new neurons,and between the different brain locations in which plasticity occurs.This review first briefly surveys the different types of plasticity and the complexity of their possible outcomes and then focuses on recent findings showing that the mammalian brain has a stem cell–independent integration of new neurons into pre-existing(mature)neural circuits.This process is still largely unknown but involves neuronal cells that have been blocked in arrested maturation since their embryonic origin(also termed“immature”or“dormant”neurons).These cells can then restart maturation throughout the animal's lifespan to become functional neurons in brain regions,such as the cerebral cortex and amygdala,that are relevant to high-order cognition and emotions.Unlike stem cell–driven postnatal/adult neurogenesis,which significantly decreases from small-brained,short-living species to large-brained ones,immature neurons are particularly abundant in large-brained,long-living mammals,including humans.The immature neural cell populations hosted in these complex brains are an interesting example of an“enlarged road”in the phylogenetic trend of plastic potential decreases commonly observed in the animal world.The topic of dormant neurons that covary with brain size and gyrencephaly represents a prospective turning point in the field of neuroplasticity,with important translational outcomes.These cells can represent a reservoir of undifferentiated neurons,potentially granting plasticity within the high-order circuits subserving the most sophisticated cognitive skills that are important in the growing brains of young,healthy individuals and are frequently affected by debilitating neurodevelopmental and degenerative disorders. 展开更多
关键词 adult neurogenesis AMYGDALA brain plasticity cerebral cortex comparative approach evolution immature neurons
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全科医学住院医师规范化培训延期结业成因及改革策略的跨国对比研究
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作者 温大志 李珍淑 +4 位作者 李贞姬 王妮 刘冬 周宪春 玄春花 《中国全科医学》 北大核心 2026年第1期58-66,共9页
本文聚焦全科医学住院医师规范化培训(以下简称住培)延期结业问题,对世界上11个有代表性的发达国家、发展中国家的培训体系、延期现状、成因及改革策略展开跨国对比分析。研究发现,全球全科住培延期结业现象普遍,延期率受临床资源短缺... 本文聚焦全科医学住院医师规范化培训(以下简称住培)延期结业问题,对世界上11个有代表性的发达国家、发展中国家的培训体系、延期现状、成因及改革策略展开跨国对比分析。研究发现,全球全科住培延期结业现象普遍,延期率受临床资源短缺、考核标准提升、突发公共卫生事件及住院医师心理健康等多重因素影响,发展中国家因区域资源不均问题更显突出。各国应对策略呈现差异化特点:美国依托动态评估机制优化培训路径,日本通过政策激励提升基层医生留存率,中国借助信息化手段强化过程管理等。破解该问题需从适应性培训模式重构、支持性生态网络构建、危机响应机制迭代三大维度协同发力,在效率与人文、标准与个性间寻求平衡,以提升全科医学教育韧性与医疗服务质量。 展开更多
关键词 全科医学 住院医师规范化培训 延期结业 跨国比较 卫生人力
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基层医疗卫生机构实现慢性病医防融合业务模式的关键机制和优化对策研究
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作者 李艳 黄豪 +3 位作者 石建伟 宋玮 祝墡珠 唐岚 《中国全科医学》 北大核心 2026年第1期108-114,共7页
背景在人口老龄化与慢性病负担加剧的背景下,传统的“重治轻防”模式已难以应对挑战并亟须构建医防融合的综合防治体系。尽管国家层面已出台多项政策推动医防融合,但基层医疗卫生机构在实施过程中仍面临诸多困境:一是缺乏系统性的实施... 背景在人口老龄化与慢性病负担加剧的背景下,传统的“重治轻防”模式已难以应对挑战并亟须构建医防融合的综合防治体系。尽管国家层面已出台多项政策推动医防融合,但基层医疗卫生机构在实施过程中仍面临诸多困境:一是缺乏系统性的实施路径指导;二是各地实践模式差异较大,缺乏共性机制提炼;三是现有研究多聚焦于医共体层面,对基层医疗卫生机构作为独立主体的医防融合模式研究不足。因此本研究聚焦基层医疗卫生机构这一核心载体,通过多案例进行机制分析,旨在破解“如何实现有效融合”的共性路径问题并提出优化对策。目的分析基层医疗卫生机构实现慢性病医防融合业务模式的关键实现机制,为各地基层医疗卫生机构探索符合当地实际情况的医防融合式慢病管理服务模式提供参考。方法于2024年11月采用文献研究法梳理、总结医防融合的文献案例,然后借鉴彩虹模型的4个层面、7个条件运用定性比较分析针对基层医疗卫生机构开展的慢性病医防融合业务的14个案例进行良好慢性病医防融合效果的实现机制探索,进而开展半结构化访谈提出优化意见。结果共有4条组态路径能有效提升基层社区慢性病医防融合效果,组态路径1中微观整合型、组态路径2微观及支持要素层整合型、组态路径3多层面整合型和组态路径4全层面整合型,4条组态路径的组合覆盖率0.857,能够解释大多数案例中的良好医防融合效果,组合一致性1.000,能够很好地解释良好医防融合效果的产生路径。服务整合和功能整合是实现良好医防融合效果的核心基础,分别强调连续的慢性病健康管理和监督考核机制的重要性,而系统整合则凸显了政策支持的关键作用。不同组态在核心条件、整合层面和支持要素上的差异表明,医防融合的实现路径可因地区资源和政策条件的不同而灵活调整,并非单一模式。结论为实现基层医疗卫生机构慢性病医防融合业务的可持续良好发展,需要从宏观层面加强政策支持和系统整合,中观层面促进多层面协作和资源下沉,微观层面强化服务整合、注重团队人员整合以确保健康管理的连续性,支持要素方面建立有效的监督考核机制和绩效激励机制。 展开更多
关键词 基层医疗卫生机构 慢性病 医防融合 定性比较分析 彩虹模型
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A Time-Domain Comparator Based Skipping-Window SAR ADC 被引量:1
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作者 Liangbo Xie Yan Ren +2 位作者 Mu Zhou Xiaolong Yang Zhengwen Huang 《Computers, Materials & Continua》 SCIE EI 2021年第11期1597-1609,共13页
This paper presents an energy efficient successive-approximation register(SAR)analog-to-digital converter(ADC)for low-power applications.To improve the overall energy-efficiency,a skipping-window technique is used to ... This paper presents an energy efficient successive-approximation register(SAR)analog-to-digital converter(ADC)for low-power applications.To improve the overall energy-efficiency,a skipping-window technique is used to bypass corresponding conversion steps when the input falls in a window indicated by a time-domain comparator,which can provide not only the polarity of the input,but also the amount information of the input.The timedomain comparator,which is based on the edge pursing principle,consists of delay cells,two NAND gates,two D-flip-flop register-based phase detectors and a counter.The digital characteristic of the comparator makes the design more flexible,and the comparator can achieve noise and power optimization automatically by simply adjusting the delay cell number.An energy efficient digital-to-analog converter(DAC)control scheme suitable for the skipping window technique is also developed to reduce the switching energy during SAR conversion.Together with the skipping-window technique,the linearity and the power consumption of the SAR ADC are improved.The impact of different window sizes on comparison cycles,DAC switching energy and the overall energy efficiency is analyzed.Simulation results show that the proposed skipping-window technique can improve the overall energy-efficiency of the SAR ADC,as well as the linearity,and the optimized window size for the overall energy efficiency will vary with the DAC switching energy. 展开更多
关键词 Skipping-window technique DAC switching scheme timedomain comparator low-power
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Trinary magnitude comparator using SLM based Savart plate 被引量:1
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作者 Animesh Bhattacharya Shyandeep Das +2 位作者 Arijit Sarkar Nabanita Bose Amal K Ghosh 《Optoelectronics Letters》 EI 2019年第6期415-419,共5页
The demand of present technology inviting the popularity of multivalued optical computation system to coup up with the latest scenario of ultrahigh processing speed and handling large amount of data The magnitude comp... The demand of present technology inviting the popularity of multivalued optical computation system to coup up with the latest scenario of ultrahigh processing speed and handling large amount of data The magnitude comparator is the heart of the arithmetic and logic unit(ALU)in any logical processing and computing system.In this paper,a trinary magnitude comparator circuit has been proposed and implemented with modified trinary number(MTN)system.Optical tree architecture(OTA)of the proposed circuit has been realized reasonably using Savart plate and spatial light modulators(SLM).A simulation algorithm has also been developed and implemented to prove the authenticity of the proposed circuit through the simulation. 展开更多
关键词 comparator system. MAGNITUDE
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A Novel Power Optimization Method by Minimum Comparator Number Algorithm for Pipeline ADCs 被引量:1
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作者 宁宁 吴霜毅 +1 位作者 王向展 杨谟华 《Journal of Electronic Science and Technology of China》 2007年第1期75-80,共6页
The effects of stage numbers on power dissipation of pipeline analog-to-digital converter (ADC) are studied and a novel design method aiming for power optimization is presented. In this method, a minimum comparator ... The effects of stage numbers on power dissipation of pipeline analog-to-digital converter (ADC) are studied and a novel design method aiming for power optimization is presented. In this method, a minimum comparator number algorithm (MCNA) is first introduced, and then the optimum distribution of resolutions through pipeline ADC stages is deduced by MCNA. Based on the optimum stage-resolution distribution, an optimization method is established, which examines the precise function between ADC power and stage resolutions with a parameter of power ratio (Rp). For 10-bit pipeline ADC with scaling down technology, the simulation results by using MATLAB CAD tools show that an eight-stage topology with 1-bit RSD correction achieves the power optimization indicated by the power reduction ratio. 展开更多
关键词 minimum comparator number algorithm pipeline analog-to-digital converter power dissipation scaling down stage resolution
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THE DESIGN OF THE HIGH SPEED AND HIGH PRECISION LATCHING VOLTAGE COMPARATOR ZJ03
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作者 毛培法 江来喜 《Journal of Electronics(China)》 1991年第2期163-168,共6页
The design of a new type of latching voltage comparator ZJ03 is described.Thecommon voltage comparators consist of multistage DC amplifiers,for which it is difficult to realizehigh speed and high precision.The ZJ03 co... The design of a new type of latching voltage comparator ZJ03 is described.Thecommon voltage comparators consist of multistage DC amplifiers,for which it is difficult to realizehigh speed and high precision.The ZJ03 comparator contains a controlled positive feedbackamplifier.Therefore,it is capable of realizing high speed and high precision.For improving theperformance and producibility,the tolerance extension,design centering and potential adaptingtechniques are used in the design of comparator ZJ03. 展开更多
关键词 VOLTAGE comparator Latching VOLTAGE comparator TOLERANCE EXTENSION POTENTIAL ADAPTING
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Single-Bit Comparator in Quantum-Dot Cellular Automata (QCA) Technology Using Novel QCAXNOR Gates
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作者 Ali Hussien Majeed Mohd Shamian Zainal +1 位作者 Esam Alkaldy Danial Md.NorNor 《Journal of Electronic Science and Technology》 CAS CSCD 2021年第3期263-273,共11页
To fill the continuous needs for faster processing elements with less power consumption causes large pressure on the complementary metal oxide semiconductor(CMOS)technology developers.The scaling scenario is not an op... To fill the continuous needs for faster processing elements with less power consumption causes large pressure on the complementary metal oxide semiconductor(CMOS)technology developers.The scaling scenario is not an option nowadays and other technologies need to be investigated.The quantum-dot cellular automata(QCA)technology is one of the important emerging nanotechnologies that have attracted much researchers’attention in recent years.This technology has many interesting features,such as high speed,low power consumption,and small size.These features make it an appropriate alternative to the CMOS technique.This paper suggests three novel structures of XNOR gates in the QCA technology.The presented structures do not follow the conventional approaches to the logic gates design but depend on the inherent capabilities of the new technology.The proposed structures are used as the main building blocks for a single-bit comparator.The resulted circuits are simulated for the verification purpose and then compared with existing counterparts in the literature.The comparison results are encouraging to append the proposed structures to the library of QCA gates. 展开更多
关键词 NANOTECHNOLOGY quantum-dot cellular automata(QCA) QCA comparator XNOR gate XOR gate
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Brief introduction for search and determination of the comparator product for generic medicinal product application in the EU
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作者 Jianzhao Niu Dongsheng Yang Mingdi Xu 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2018年第11期805-812,共8页
It is vital segment to choose the right comparator product during the development and study of generic medicinal product, and this is also definitely specified in the relevant documents from the China Food and Drug Ad... It is vital segment to choose the right comparator product during the development and study of generic medicinal product, and this is also definitely specified in the relevant documents from the China Food and Drug Administration (CFDA)that the comparator product should be innovator product or internationally recognized same medicinal product,which is used in the re-evaluation of generic medicinal product or marketed authorization application of the generic medicinal product.To facilitate the domestic and foreign pharmaceutical enterprises to choose and determine comparator product,four medicinal product evaluation procedures,as well as the corresponding marketed medicinal product list,are detailed elaborated in this paper.At the same time, by taking the Mifepristone Tablet (200mg)as example,the search and determination process of the comparator product for generic medicinal product application in the EU is illustrated with the combination of different marketed medicinal product lists. 展开更多
关键词 comparator product Re-evaluation of generic medicinal product Marketing authorization application Mifepristone tablet
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Novel Design of Low-power Multiplex Differential Voltage Comparators
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作者 WANG Hong-yi LAI Xin-quan LI Yu-shan 《Semiconductor Photonics and Technology》 CAS 2007年第1期1-6,共6页
A novel design of multiplex differential voltage comparators(MDVC) is presented for reducing current and power dissipation. According to the special properties of relational operation and logical operation, parts of t... A novel design of multiplex differential voltage comparators(MDVC) is presented for reducing current and power dissipation. According to the special properties of relational operation and logical operation, parts of the comparators are redundant in some instances, and thus can be turned off. By selecting and switching the current routes, several effective differential pairs are biased by a single tail current stage-by-stage and the redundant comparators are turned off by cutting their tail currents. As a result, the quiescent current and power consumption are greatly decreased. The switching of current is achieved by the input differential pair transistors themselves and hence no extra switches are required. When a MDVC is used in a flash analog-to-digital converter(ADC), its current dissipation is much lower than that of the conventional comparators. This architecture can also be used in window-comparators, maximum or minimum comparators, and comparators for logical operations. The power dissipation in all these cases could be reduced significantly. 展开更多
关键词 LOW-POWER comparatorS multiplex comparators window comparators flash ADC switchedcurrent
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A Two-Dimension Time-Domain Comparator for Low Power SAR ADCs
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作者 Liangbo Xie Sheng Li +1 位作者 Yan Ren Zhengwen Huang 《Computers, Materials & Continua》 SCIE EI 2020年第11期1519-1529,共11页
This paper presents a two-dimension time-domain comparator suitable for low power successive-approximation register(SAR)analog-to-digital converters(ADCs).The proposed two-dimension time-domain comparator consists of ... This paper presents a two-dimension time-domain comparator suitable for low power successive-approximation register(SAR)analog-to-digital converters(ADCs).The proposed two-dimension time-domain comparator consists of a ring oscillator collapse-based comparator and a counter.The propagation delay of a voltage controlled ring oscillator depends on the input.Thus,the comparator can automatically change the comparison time according to its input difference,which can adjust the power consumption of the comparator dynamically without any control logic.And a counter is utilized to count the cycle needed to finish a comparison when the input difference is small.Thus,the proposed comparator can not only provide the polarity of the input,but also the amount information of the input,which helps to skip most of the SAR cycles when the initial input is small.Thus,most energy can be saved when the initial input is small.The proposed time-domain comparator is designed in 0.18μm CMOS technology.Simulation results demonstrate that the comparator can not only save power consumption,but also give the design flexibility,and the current is only nA level when the supply voltage is 0.6 V. 展开更多
关键词 Time-domain comparator two dimensions low power
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Design of Low Power Comparator Using DG Gate
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作者 Bahram Dehghan Abdolreza Roozbeh Jafar Zare 《Circuits and Systems》 2014年第1期7-12,共6页
In recent studies, reversible logic has emerged as a great scene of research, having applications in low power CMOS circuits, optical computing, quantum computing and nanotechnology. The classical logic gates such as ... In recent studies, reversible logic has emerged as a great scene of research, having applications in low power CMOS circuits, optical computing, quantum computing and nanotechnology. The classical logic gates such as AND, OR, EXOR and EXNOR are not reversible. In the existing literature, reversible sequential circuits designs are offered that are improved for the number of the garbage outputs and reversible gates. Minimizing the number of garbage is very noticeable. In the present paper, we show a design of the reversible comparator based on the quantum gates implementation of the reversible DG gate. The reversible DG gate is designed by using 3 × 3 quantum gates such as NOT, CNOT, Controlled-V and Controlled-V+ gates. Also, we have used the TR gate and various types of quantum gates in the implementation results. Low power three-bit comparator is designed using DG Gate, New Gate and Fredkin Gate. In order to evaluate the benefit of using the DG gate proposed in this paper, one-bit comparator is constructed. The design is useful for the future computing techniques like quantum computers. The proposed designs are implemented using VHDL and functionally investigated using Quartus II simulator. 展开更多
关键词 REVERSIBLE Logic comparator TR and DG GATE Quantum Cost GARBAGE Output
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A 0.5-V, 1.2-GS/s, 6-Bit Flash ADC Using Temporarily-Boosted Comparator
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作者 Kenichi Ohhata Masataro Iwamoto Naoto Yamaguchi 《Circuits and Systems》 2015年第8期179-187,共9页
A low-voltage, high-speed flash ADC is designed. The bottleneck of the operation speed in the low-voltage region is the delay time increase of the comparator. The temporarily boosted comparator is proposed to address ... A low-voltage, high-speed flash ADC is designed. The bottleneck of the operation speed in the low-voltage region is the delay time increase of the comparator. The temporarily boosted comparator is proposed to address this problem. The proposed circuit only boosts the supply voltage in the comparison phase, and therefore, can reduce the delay time while keeping the power overhead to a minimum. Moreover, the body bias control calibration is combined with the temporarily boosted technique. This helps to create a low-power and high-precision comparator. A 0.5-V, 6-bit flash ADC was designed by using 65-nm CMOS technology to demonstrate the effectiveness of the proposed technique. The simulation results showed a high sampling frequency of 1.2 GHz, a low power consumption of 1.4 mW, and an FOM of 28 fJ/conv.-step even at a low supply voltage of 0.5 V. 展开更多
关键词 ADC Low VOLTAGE Flash comparator Calibration
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Analysis on the Magnetic Shielding Effectiveness of DC Current Comparator
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作者 Jiayun Song Pan Pan +2 位作者 Qizheng Ji Shuqiang Wang Biye Liu 《Journal of Applied Mathematics and Physics》 2016年第2期478-486,共9页
There are magnetic interference problems in the applications of DC current comparator. Analysis on the magnetic effectiveness which is applied by the external magnetic field is introduced in this paper. The effectiven... There are magnetic interference problems in the applications of DC current comparator. Analysis on the magnetic effectiveness which is applied by the external magnetic field is introduced in this paper. The effectiveness is proved by the actual results which are compared with the magnetic- circuit method and the finite element method. In addition, the reference comment is given which can be used in the practical work of DC current comparator shield design. 展开更多
关键词 Magnetic Shielding Effectiveness DC Current comparator the Magnetic-Circuit Method the Finite Element Method
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澳大利亚Haese版IBDP和中国人教A版高中数学教材中数学史的比较研究 被引量:2
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作者 李立斌 王洁 朱家生 《数学教育学报》 北大核心 2025年第1期13-19,共7页
对澳大利亚Haese版IBDP和中国人教A版高中数学教材中的数学史进行对比研究,比较二者在数量、栏目分布、内容类别、知识领域、运用方式、信息载体、多元文化等方面的异同.对融入数学史的高中数学教材提出如下建议:增加数学史数量,隐性呈... 对澳大利亚Haese版IBDP和中国人教A版高中数学教材中的数学史进行对比研究,比较二者在数量、栏目分布、内容类别、知识领域、运用方式、信息载体、多元文化等方面的异同.对融入数学史的高中数学教材提出如下建议:增加数学史数量,隐性呈现数学史;强化数学思想方法,挖掘几何数学史;呈现文明古国数学成就,促进多元文化均衡;保证图文数学史质量,丰富信息载体形式;融入正文与例习题,顺应式呈现数学史. 展开更多
关键词 数学史 数学教材 比较研究
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重塑全球化共识:基于中国道路的静态与动态比较优势理论分析 被引量:1
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作者 余宇新 张瑾 《上海交通大学学报(哲学社会科学版)》 北大核心 2025年第1期92-106,共15页
针对贫富差距扩大与全球经济供需结构失衡的问题,本文通过梳理全球化共识的演变历程,融合了静态与动态比较优势理论,重新解构全球化红利的分配逻辑以适应技术革新的现实背景,提出“共享繁荣,共谋发展”的新全球化共识框架。这一共识强... 针对贫富差距扩大与全球经济供需结构失衡的问题,本文通过梳理全球化共识的演变历程,融合了静态与动态比较优势理论,重新解构全球化红利的分配逻辑以适应技术革新的现实背景,提出“共享繁荣,共谋发展”的新全球化共识框架。这一共识强调市场导向与尊重国家自主选择权的合作模式,旨在达成国际合作的最大公约数,进而推动全球化向深度与广度拓展。本研究对于应对“逆全球化”趋势,缓解国际经济秩序的动荡,提供了理论支撑与实践指导。 展开更多
关键词 华盛顿共识 全球化共识 静态比较优势原理 动态比较优势原理 全球化红利
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奥赛利定联合髂筋膜间隙阻滞对老年衰弱患者股骨近端防旋髓内钉内固定术后康复质量的影响 被引量:1
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作者 刘克 王帅 +3 位作者 张帅帅 孙志明 王大龙 叶文学 《中国新药与临床杂志》 北大核心 2025年第2期145-149,共5页
目的评价奥赛利定联合髂筋膜间隙阻滞对老年衰弱患者股骨近端防旋髓内钉(PFNA)内固定术后康复质量的影响。方法选择全身麻醉下行PFNA内固定术老年衰弱患者60例,随机分为对照组和试验组,每组30例。麻醉前5 min,试验组静脉注射奥赛利定1 ... 目的评价奥赛利定联合髂筋膜间隙阻滞对老年衰弱患者股骨近端防旋髓内钉(PFNA)内固定术后康复质量的影响。方法选择全身麻醉下行PFNA内固定术老年衰弱患者60例,随机分为对照组和试验组,每组30例。麻醉前5 min,试验组静脉注射奥赛利定1 mg,对照组注射舒芬太尼5μg,所有患者均行全身麻醉并实施超声引导下髂筋膜间隙阻滞,术后行患者自控静脉镇痛(PCIA)。记录术中丙泊酚、瑞芬太尼用量;记录术前24 h和术后2、6、24、48 h的视觉模拟评分法(VAS)评分,术后24 h内镇痛泵按压次数和补救镇痛情况;检测术前和术后2、24 h白细胞介素(IL)-6、肿瘤坏死因子(TNF)-α和C反应蛋白(CRP)水平;记录术后苏醒时间、拔管时间、麻醉恢复室(PACU)停留时间和不良反应发生情况,采用恢复质量量表(QoR-15)评分评估术后早期恢复质量。结果与对照组相比,试验组术中丙泊酚和瑞芬太尼用量显著减少(P<0.05)。与术前24 h相比,2组术后2~48 h VAS评分均不同程度下降(P<0.05),试验组显著低于对照组(P<0.05)。试验组术后48 h内镇痛泵按压次数和补救镇痛次数均显著少于对照组(P<0.01)。与术前24 h相比,2组术后2、24 h的IL-6、TNF-α和CRP水平均显著上升(P<0.05),QoR-15评分增加,且2组间比较差异显著(P<0.05)。与对照组相比,试验组术后苏醒时间、拔管时间、PACU停留时间明显缩短(P<0.05)。试验组不良反应发生率低于对照组(P<0.05)。结论奥赛利定联合髂筋膜间隙阻滞应用于老年衰弱患者PFNA内固定术,安全有效,能减轻术后急性疼痛,减少不良反应,有利于早期康复。 展开更多
关键词 奥赛利定 髂筋膜间隙阻滞 镇痛 老年患者 衰弱
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基于CiteSpace的国内外医疗大语言模型研究热点演进及趋势分析 被引量:1
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作者 牛奔 朱晓倩 +2 位作者 杨辰 梁万年 刘珏 《中国全科医学》 北大核心 2025年第25期3200-3208,共9页
背景由于其强大的语言处理能力和广泛的应用潜力,以ChatGPT为代表的大语言模型引领了医疗领域自然语言处理的新趋势。目的本研究通过文献计量分析揭示2017年以来医疗大语言模型的研究热点、主题分布及未来发展方向。方法通过Web of Scie... 背景由于其强大的语言处理能力和广泛的应用潜力,以ChatGPT为代表的大语言模型引领了医疗领域自然语言处理的新趋势。目的本研究通过文献计量分析揭示2017年以来医疗大语言模型的研究热点、主题分布及未来发展方向。方法通过Web of Science、中国知网、万方数据知识服务平台和维普网数据库,系统检索和筛选2017年1月-2024年6月关于医疗大语言模型的文献。利用CiteSpace软件提取文献中的主题关键词等信息,分析并对比国内外研究的演进、热点和趋势。结果共纳入1071篇相关文献,结果显示国外研究集中于人工智能、大语言模型、深度学习、知识图谱等技术在医学中的应用,而国内研究则相对较少,侧重于中文医学问答系统构建和医疗数据非结构化问题处理。结论深化医疗数据挖掘,拓展多场景应用,并借鉴国际大语言模型的微调和应用评估经验,促进我国医疗大语言模型技术的发展和医学领域应用。 展开更多
关键词 卫生保健提供 医疗健康 大语言模型 文献计量分析 CITESPACE 人工智能
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