With the increasing importance of multimodal data in emotional expression on social media,mainstream methods for sentiment analysis have shifted from unimodal to multimodal approaches.However,the challenges of extract...With the increasing importance of multimodal data in emotional expression on social media,mainstream methods for sentiment analysis have shifted from unimodal to multimodal approaches.However,the challenges of extracting high-quality emotional features and achieving effective interaction between different modalities remain two major obstacles in multimodal sentiment analysis.To address these challenges,this paper proposes a Text-Gated Interaction Network with Inter-Sample Commonality Perception(TGICP).Specifically,we utilize a Inter-sample Commonality Perception(ICP)module to extract common features from similar samples within the same modality,and use these common features to enhance the original features of each modality,thereby obtaining a richer and more complete multimodal sentiment representation.Subsequently,in the cross-modal interaction stage,we design a Text-Gated Interaction(TGI)module,which is text-driven.By calculating the mutual information difference between the text modality and nonverbal modalities,the TGI module dynamically adjusts the influence of emotional information from the text modality on nonverbal modalities.This helps to reduce modality information asymmetry while enabling full cross-modal interaction.Experimental results show that the proposed model achieves outstanding performance on both the CMU-MOSI and CMU-MOSEI baseline multimodal sentiment analysis datasets,validating its effectiveness in emotion recognition tasks.展开更多
Commercial aircraft family design can reduce development costs, shorten development cycles, and expand the market coverage of aircraft. Commercial aircraft family development has become one of the most important featu...Commercial aircraft family design can reduce development costs, shorten development cycles, and expand the market coverage of aircraft. Commercial aircraft family development has become one of the most important features of modern aircraft design. This paper explores the effects of commonality on different aircraft models in a commercial aircraft family. The existing product commonality indexes are summarized and their limitations in the application to aircraft design are discussed. Then a new component commonality index is proposed based on the component decomposition structure. A model for calculating the aircraft program value is established,which considers development costs, manufacturing costs, sale price, operation costs and residual costs. The effects of aircraft commonality on time and economic costs of both development and manufacturing, and on sale price, are analyzed and quantified. The commonality evaluation strategy is obtained, which features comprehensive consideration of the aircraft program value and time costs. The break-even analysis of aircraft is proceeded on the basis of costs and price data. By using a real option method, the strategy considers the uncertainty of the aircraft program and the flexibility of the manufacturer. This strategy proves to be rational and applicable to aircraft design based on the calculation of three examples and the analysis of parameter sensitivity.展开更多
It is essential to manage customers' diverse desires and to keep manufacturing costs as low as possible for survival in competition and eventually in production.Sharing resources in manufacturing for different pro...It is essential to manage customers' diverse desires and to keep manufacturing costs as low as possible for survival in competition and eventually in production.Sharing resources in manufacturing for different products is a vital method of accomplishing this goal.The advantages of using a common process in production are stated in the literature.However,the mathematical models as well as simulation or conceptual models are not sufficient.The main objective of this paper is to develop mathematical models for multiproduct and multistage production under quality and breakdown uncertainties.The idea of the process commonality is incorporated in the proposed models.The models are validated by primary data collected from a Malaysian company and comparison of the timely requirement schedules of earlier MRP II and the proposed models under stable and perfect production environments.An appreciable convergence of the outcomes is observed.However,the proposed models are carrying additional information about the available locations of the parts in a time frame.After validation,the effects of process commonality on cost,capacity and the requirement schedule under uncertainties are examined.It is observed that the use of common processes in manufacturing is always better than the non-commonality scenario in terms of production cost.However,the increase in capacity requirement for commonality designs is higher for an ideal system,while it is less when the system suffers from breakdowns and a quality problem.展开更多
Cooperative spectrum monitoring with multiple sensors has been deemed as an efficient mechanism for improving the monitoring accuracy and enlarging the monitoring area in wireless sensor networks.However,there exists ...Cooperative spectrum monitoring with multiple sensors has been deemed as an efficient mechanism for improving the monitoring accuracy and enlarging the monitoring area in wireless sensor networks.However,there exists redundancy among the spectrum data collected by a sensor node within a data collection period,which may reduce the data uploading efficiency.In this paper,we investigate the inter-data commonality detection which describes how much two data have in common.We define common segment set and divide it into six categories firstly,then a method to measure a common segment set is conducted by extracting commonality between two files.Moreover,the existing algorithms fail in finding a good common segment set,so Common Data Measurement(CDM)algorithm that can identify a good common segment set based on inter-data commonality detection is proposed.Theoretical analysis proves that CDM algorithm achieves a good measurement for the commonality between two strings.In addition,we conduct an synthetic dataset which are produced randomly.Numerical results shows that CDM algorithm can get better performance in measuring commonality between two binary files compared with Greedy-String-Tiling(GST)algorithm and simple greedy algorithm.展开更多
In the science fiction novel titled The Planet of the Apes （1963）, Pierre Boulle tells a story about a completely reversed world where the apes dominate the humans. Coming from the normal world that is ours, a small...In the science fiction novel titled The Planet of the Apes （1963）, Pierre Boulle tells a story about a completely reversed world where the apes dominate the humans. Coming from the normal world that is ours, a small group of people is totally embarrassed and confused by observing this strange world. On the planet of the apes that they have discovered, it is the apes that are more intelligent than the humans. On the earth, it was the other way around. That observation results in their perplexity. The two communities, human and simian, bear with one another the relationship that corresponds to what Lotman calls ＂enantiomorphic pairings＂. In this context, a series of questions deserves to be raised： Is a ＂common language＂ possible between the two communities in the enantiomorphic pairings？ If the answer is yes, under what conditions could they succeed in opening up a space where they can have something in common？ In rereading The Planet of the Apes with reference to Lotman＇s semiotics of culture, we would like to formulate a response to those questions. Our claim is that the experience of finitude of one＇s own language can make possible an access to the new form of universality requisite for the cross-cultural communication： commonality without common points.展开更多
The common design of serial civil aircraft, an important strategy of modern civil aircraft research and develop-ment, minimizes the whole life cycle cost of civil aircraft through asset reuse and resource sharing. How...The common design of serial civil aircraft, an important strategy of modern civil aircraft research and develop-ment, minimizes the whole life cycle cost of civil aircraft through asset reuse and resource sharing. However, the existing estimating model for the R&D cost of civil aircraft ignores the effects of common design, so the value estimated by estimating derivative models is significantly inconsistent with the actual one. To solve this problem, a novel assessment method for civil aircraft commonality indicators is developed based on fuzzy set in the present study, exploiting the attributes and structural parameters of the aircraft to be assessed as input to determine the degree of membership that pertains to the commonality sub-interval as the commonality indicator.Then the BP(Back Propagation) neural network algorithm is adopted to establish the relationship between the common index and the decrease rate of the R&D cost of derivative models. The model employs over a dozen typical civil aircraft models(e.g., Boeing, Airbus, and Bombardier) as the sample data for network learning training to build a mature neural network model for estimating the R&D cost of novel derivative models. As revealed from the comparative analysis on the calculated results of the samples, the estimated results of the model given the effects of commonality in the present study exhibit higher estimation accuracy and value for future work.展开更多
Component commonality has been cited as a powerful approach for manufacturers to cope with increased component proliferation and to control inventory costs. To fully realize its potential benefits, one needs a clear u...Component commonality has been cited as a powerful approach for manufacturers to cope with increased component proliferation and to control inventory costs. To fully realize its potential benefits, one needs a clear understanding of its impacts on the system. In this paper, the feasibility of using a simulation model to provide a systematic perspective for manufacturing firms to implement a commonality strategy is demonstrated. Alternative commonality strategies including the stage of employing commonality and the allocation policies are simulated. Several interesting results on effects of commonality, allocation policies, and optimal solutions are obtained. We then summarize qualitative insights and managerial implications into the component commonality design and implementation, and inventory management in a general multi-stage assembly system.展开更多
This paper presents a systematic approach to estimate the value of commonality in products that involve multiple stage assemblies. In particular, the inventory savings are quantified with a mathematical model. The pur...This paper presents a systematic approach to estimate the value of commonality in products that involve multiple stage assemblies. In particular, the inventory savings are quantified with a mathematical model. The purpose is to assist product deisgn teams to make rational decisions in assigning unique parts or pursuing component standardization. In order to enhance the usability of the model, approximations are made to simplify the model and calculations.展开更多
BACKGROUND Pancreaticobiliary maljunction(PBM)is a rare congenital abnormality in pancreaticobiliary duct development.PBM is commonly found in children,and it often leads to acute pancreatitis and other diseases as a ...BACKGROUND Pancreaticobiliary maljunction(PBM)is a rare congenital abnormality in pancreaticobiliary duct development.PBM is commonly found in children,and it often leads to acute pancreatitis and other diseases as a result of pancreaticobiliary reflux.Roux-en-Y choledochojejunostomy is a common surgical method for the treatment of PBM,but there are several associated complications that may occur after this operation.CASE SUMMARY The patient,a 12-year-old female,was hospitalized nearly 20 times in 2021 for recurrent acute pancreatitis.In 2022,she was diagnosed with PBM and underwent laparoscopic common bile duct resection and Roux-en-Y choledochojejunostomy in a tertiary hospital.In the first year after surgery,the patient had more than 10 recurrent acute pancreatitis episodes.After undergoing abdominal computed tomography and other examinations,she was diagnosed with“residual bile duct stones and recurrent acute pancreatitis”.On January 30,2024,the patient was admitted to our hospital due to recurrent upper abdominal pain and was cured through endoscopic retrograde cholangiopancreatography.CONCLUSION This article reports a case of a child with distal residual common bile duct stones and recurrent acute pancreatitis after Roux-en-Y choledochojejunostomy for PBM.The patient was cured through endoscopic retrograde cholangiopancreatography.展开更多
In this paper,we establish common fixed point theorems for expansive map?pings on b-metric-like space and coincidence point for f-weakly isotone increasing mappings in partially ordered b-metric-like space.The main re...In this paper,we establish common fixed point theorems for expansive map?pings on b-metric-like space and coincidence point for f-weakly isotone increasing mappings in partially ordered b-metric-like space.The main results generalize and extend several well-known comparable results from the existing literature.Moreover,some examples are provided to illustrate the main results.展开更多
The recent rapid development in information systems （ISs） has resulted in a critical need for integration and interoperability between heterogeneous ISs in various domains, using specific commonalities. However, sto...The recent rapid development in information systems （ISs） has resulted in a critical need for integration and interoperability between heterogeneous ISs in various domains, using specific commonalities. However, stovepipe systems have been caused due to inconsistencies in planning IS architecture among stakeholders. So far, there has been no research on an enterprise architecture framework （EAF） that can satisfy with the coefficient factors of system architecture （SA） and enterprise architecture （EA）. This paper proposes a new EAF that can resolve the problems inherent in existing legacy EAFs and their features. EAFoC （Enterprise Architecture Framework based on Commonality） is based on commonality that can be satisfied as the coefficient factors in both SA and EA within a common information technology （IT） domain. Thus, it should be possible to integrate an established heterogeneous framework for each stakeholder＇s view. Consequently, the most important contribution of this paper is to establish the appropriate EAFoC for the development of consistent IS architecture, smooth communication among stakeholders, systematic integration management of diversified and complicated new IT technologies, interoperability among heterogeneous ISs, and reusability based on commonality with other platforms.展开更多
[Objectives]To investigate the antibacterial mechanism of Common Cnidium Fruit using network pharmacology.[Methods]Active components and targets of Common Cnidium Fruit were screened and obtained using the TCMSP datab...[Objectives]To investigate the antibacterial mechanism of Common Cnidium Fruit using network pharmacology.[Methods]Active components and targets of Common Cnidium Fruit were screened and obtained using the TCMSP database and HIT2.0 database.The collected targets were intersected with antibacterial/bacteriostatic targets obtained from the GeneCards database and OMIM database to identify the antibacterial/bacteriostatic targets of Common Cnidium Fruit.The active component-target network diagram of Common Cnidium Fruit was constructed using Cytoscape software and topological analysis was performed.GO enrichment analysis was performed on the target genes using the DAVID database.[Results]Screening yielded 25 active components of Common Cnidium Fruit,corresponding to 77 targets.Analysis identified 25 core antibacterial/bacteriostatic targets for Common Cnidium Fruit.Network analysis indicated that Common Cnidium Fruit may exert antibacterial/bacteriostatic effects through active components such asβ-sitosterol,stigmasterol,and xanthoxylin,while activating the body's immune regulatory functions by acting on targets including CASP3,PTGS2,BCL2,JUN,and ESR1.[Conclusions]Common Cnidium Fruit may exert antibacterial/bacteriostatic effects through multiple pathways via a mechanism involving multiple components,multiple targets,and multiple pathways.展开更多
BACKGROUND At present,there are few studies on the risk factors for bile leakage after laparoscopic common bile duct exploration(LCBDE)for older patients with choledocholithiasis.AIM To identify the potential risk fac...BACKGROUND At present,there are few studies on the risk factors for bile leakage after laparoscopic common bile duct exploration(LCBDE)for older patients with choledocholithiasis.AIM To identify the potential risk factors for bile leakage after LCBDE in older patients.METHODS A retrospective,single-center observational analysis was performed on patients aged≥70 years with choledocholithiasis treated by LCBDE who were admitted to our center between January 2011 and August 2022.The included patients were divided into non-bile leakage and bile leakage groups.Risk factors were determined by analyzing the observation indicators.RESULTS Seventy older patients with choledocholithiasis who underwent LCBDE were included.Univariate analysis showed that positive culture of bile bacteria was a risk factor for bile leakage after LCBDE(P<0.05).We further analyzed the bile bacteria,and univariate analysis showed that Enterococcus faecalis(E.faecalis)(P<0.05)and Pseudomonas aeruginosa(P<0.05)were associated with an increased risk of postoperative bile leakage in older patients(P<0.05).Multivariate analysis showed that E. faecalis was an independent risk factor for postoperative bile leakage in older patients (P < 0.05). Theresults of antibiotic sensitivity analysis showed that E. faecalis had 100% susceptibility to penicillin, ampicillin,linezolid, vancomycin, and furantoin.CONCLUSIONE. faecalis-associated biliary tract infection is an independent risk factor for bile leakage after LCBDE in olderpatients with choledocholithiasis. We suggest coverage with antibiotics to which E. faecalis is sensitive.展开更多
BACKGROUND Laparoscopic cholecystectomy(LC)and laparoscopic common bile duct exploration(LCBDE)are widely used in gallbladder and biliary tract diseases.During these procedures,vessels or tissues are commonly ligated ...BACKGROUND Laparoscopic cholecystectomy(LC)and laparoscopic common bile duct exploration(LCBDE)are widely used in gallbladder and biliary tract diseases.During these procedures,vessels or tissues are commonly ligated using clips.However,postoperative migration of clips to the common bile duct(CBD)or Ttube sinus tract is an overlooked complication of laparoscopic biliary surgery.Previously,most reported cases of postoperative clip migration involved metal clips,with only a few cases involving Hem-o-lok clips and review of the literature.CASE SUMMARY This report describes two cases in which Hem-o-lok clips migrated into the CBD and the T-tube sinus tract following laparoscopic surgery.Case 1 is a 68-year-old female admitted due to abdominal discomfort,and two Hem-o-lok clips were found to have migrated into the CBD 17 months after LC and LCBDE with T-tube drainage,and were removed using a stone extraction balloon.The patient was discharged smoothly after recovery.Case 2 is a 74-year-old male who underwent LC and LCBDE with T-tube drainage and laparoscopic biliary tract basket stone extraction.Nine weeks postoperatively,following T-tube removal,a Hem-o-lok clip was found in the sinus tract,and was extracted from the T-tube sinus tract.The patient recovered smoothly postoperatively.This study also reviews the literature from 2013 to July 2024 on using Hem-o-lok clips in LC and/or LCBDE treatment of gallbladder and biliary diseases and the postoperative migration of these clips into the CBD,T-tube sinus tract,or duodenum.CONCLUSION In patients with a history of LC and/or LCBDE,clip migration should be considered as a differential diagnosis.展开更多
Common bean(Phaseolus vulgaris L.)is a vital source of protein and essential nutrients for human consumption and plays a key role in sustainable agriculture due to its nitrogen-fixing ability(Nadeem et al.,2021).Kidne...Common bean(Phaseolus vulgaris L.)is a vital source of protein and essential nutrients for human consumption and plays a key role in sustainable agriculture due to its nitrogen-fixing ability(Nadeem et al.,2021).Kidney beans,a subcategory of dry common beans,are highly valued for their rich protein,dietary fiber,low fat content,and various trace elements(Garcia-Cordero et al.,2021).Despite the release of several de novo genome assemblies(Goodstein et al.,2012;Schmutz et al.,2014;Vlasova et al.,2016;Cortinovis et al.,2024),existing common bean genomes remain incomplete,particularly in complex regions such as centromeres and telomeres,limiting a comprehensive understanding of the genomic landscape.展开更多
I have a good friend named Jeff.We are both in Grade Seven and have been close friends since the beginning of this term.Jeff is tall and always wears a warm smile on his face.He is really friendly and kind.We have man...I have a good friend named Jeff.We are both in Grade Seven and have been close friends since the beginning of this term.Jeff is tall and always wears a warm smile on his face.He is really friendly and kind.We have many things in common.展开更多
The common cold is caused by a large range of respiratory viruses and is the most common disease of mankind. There is a great need for a prophylactic treatment for colds. Specific antiviral treatments are only effecti...The common cold is caused by a large range of respiratory viruses and is the most common disease of mankind. There is a great need for a prophylactic treatment for colds. Specific antiviral treatments are only effective against one group of viruses and there is a need for a non-specific treatment that can be used against all respiratory viruses. Carrageenan is a general term used to describe a range of sulfated polysaccharides extracted from edible seaweeds. Large polyanionic molecules such as carrageenan have been shown to have antiviral activity against a wide range of viruses in vitro. The strong anionic charge of carrageenan attracts and traps viruses that have positively charged areas on their surface. The trapped viruses are then unable to infect epithelial cells. Iota-carrageenan exerts its’ antiviral activity by physical means due to its high anionic charge and it does not have any pharmacological properties and therefore does not have any toxicology or known side effects from treatment. Iota-carrageenan does not have any taste or smell and, when used as a nasal spray, does not have any adverse effects. Iota-carrageenan is an ideal prophylactic treatment for the common cold and is safe for use in children. Treatment of common cold with iota-carrageenan has to date been studied in five placebo-controlled clinical trials and these trials support both efficacy as a prophylactic treatment for colds and the safety and tolerability of iota-carrageenan.展开更多
基金supported by the Natural Science Foundation of Henan under Grant 242300421220the Henan Provincial Science and Technology Research Project under Grants 252102211047 and 252102211062+3 种基金the Jiangsu Provincial Scheme Double Initiative Plan JSS-CBS20230474the XJTLU RDF-21-02-008the Science and Technology Innovation Project of Zhengzhou University of Light Industry under Grant 23XNKJTD0205the Higher Education Teaching Reform Research and Practice Project of Henan Province under Grant 2024SJGLX0126.
文摘With the increasing importance of multimodal data in emotional expression on social media,mainstream methods for sentiment analysis have shifted from unimodal to multimodal approaches.However,the challenges of extracting high-quality emotional features and achieving effective interaction between different modalities remain two major obstacles in multimodal sentiment analysis.To address these challenges,this paper proposes a Text-Gated Interaction Network with Inter-Sample Commonality Perception(TGICP).Specifically,we utilize a Inter-sample Commonality Perception(ICP)module to extract common features from similar samples within the same modality,and use these common features to enhance the original features of each modality,thereby obtaining a richer and more complete multimodal sentiment representation.Subsequently,in the cross-modal interaction stage,we design a Text-Gated Interaction(TGI)module,which is text-driven.By calculating the mutual information difference between the text modality and nonverbal modalities,the TGI module dynamically adjusts the influence of emotional information from the text modality on nonverbal modalities.This helps to reduce modality information asymmetry while enabling full cross-modal interaction.Experimental results show that the proposed model achieves outstanding performance on both the CMU-MOSI and CMU-MOSEI baseline multimodal sentiment analysis datasets,validating its effectiveness in emotion recognition tasks.
文摘Commercial aircraft family design can reduce development costs, shorten development cycles, and expand the market coverage of aircraft. Commercial aircraft family development has become one of the most important features of modern aircraft design. This paper explores the effects of commonality on different aircraft models in a commercial aircraft family. The existing product commonality indexes are summarized and their limitations in the application to aircraft design are discussed. Then a new component commonality index is proposed based on the component decomposition structure. A model for calculating the aircraft program value is established,which considers development costs, manufacturing costs, sale price, operation costs and residual costs. The effects of aircraft commonality on time and economic costs of both development and manufacturing, and on sale price, are analyzed and quantified. The commonality evaluation strategy is obtained, which features comprehensive consideration of the aircraft program value and time costs. The break-even analysis of aircraft is proceeded on the basis of costs and price data. By using a real option method, the strategy considers the uncertainty of the aircraft program and the flexibility of the manufacturer. This strategy proves to be rational and applicable to aircraft design based on the calculation of three examples and the analysis of parameter sensitivity.
文摘It is essential to manage customers' diverse desires and to keep manufacturing costs as low as possible for survival in competition and eventually in production.Sharing resources in manufacturing for different products is a vital method of accomplishing this goal.The advantages of using a common process in production are stated in the literature.However,the mathematical models as well as simulation or conceptual models are not sufficient.The main objective of this paper is to develop mathematical models for multiproduct and multistage production under quality and breakdown uncertainties.The idea of the process commonality is incorporated in the proposed models.The models are validated by primary data collected from a Malaysian company and comparison of the timely requirement schedules of earlier MRP II and the proposed models under stable and perfect production environments.An appreciable convergence of the outcomes is observed.However,the proposed models are carrying additional information about the available locations of the parts in a time frame.After validation,the effects of process commonality on cost,capacity and the requirement schedule under uncertainties are examined.It is observed that the use of common processes in manufacturing is always better than the non-commonality scenario in terms of production cost.However,the increase in capacity requirement for commonality designs is higher for an ideal system,while it is less when the system suffers from breakdowns and a quality problem.
基金supported in part by the National Natural Science Foundation of China(No.61901328)the China Postdoctoral Science Foundation (No. 2019M653558)+1 种基金the Fundamental Research Funds for the Central Universities (No. CJT150101)the Key project of National Natural Science Foundation of China (No. 61631015)
文摘Cooperative spectrum monitoring with multiple sensors has been deemed as an efficient mechanism for improving the monitoring accuracy and enlarging the monitoring area in wireless sensor networks.However,there exists redundancy among the spectrum data collected by a sensor node within a data collection period,which may reduce the data uploading efficiency.In this paper,we investigate the inter-data commonality detection which describes how much two data have in common.We define common segment set and divide it into six categories firstly,then a method to measure a common segment set is conducted by extracting commonality between two files.Moreover,the existing algorithms fail in finding a good common segment set,so Common Data Measurement(CDM)algorithm that can identify a good common segment set based on inter-data commonality detection is proposed.Theoretical analysis proves that CDM algorithm achieves a good measurement for the commonality between two strings.In addition,we conduct an synthetic dataset which are produced randomly.Numerical results shows that CDM algorithm can get better performance in measuring commonality between two binary files compared with Greedy-String-Tiling(GST)algorithm and simple greedy algorithm.
文摘In the science fiction novel titled The Planet of the Apes （1963）, Pierre Boulle tells a story about a completely reversed world where the apes dominate the humans. Coming from the normal world that is ours, a small group of people is totally embarrassed and confused by observing this strange world. On the planet of the apes that they have discovered, it is the apes that are more intelligent than the humans. On the earth, it was the other way around. That observation results in their perplexity. The two communities, human and simian, bear with one another the relationship that corresponds to what Lotman calls ＂enantiomorphic pairings＂. In this context, a series of questions deserves to be raised： Is a ＂common language＂ possible between the two communities in the enantiomorphic pairings？ If the answer is yes, under what conditions could they succeed in opening up a space where they can have something in common？ In rereading The Planet of the Apes with reference to Lotman＇s semiotics of culture, we would like to formulate a response to those questions. Our claim is that the experience of finitude of one＇s own language can make possible an access to the new form of universality requisite for the cross-cultural communication： commonality without common points.
文摘The common design of serial civil aircraft, an important strategy of modern civil aircraft research and develop-ment, minimizes the whole life cycle cost of civil aircraft through asset reuse and resource sharing. However, the existing estimating model for the R&D cost of civil aircraft ignores the effects of common design, so the value estimated by estimating derivative models is significantly inconsistent with the actual one. To solve this problem, a novel assessment method for civil aircraft commonality indicators is developed based on fuzzy set in the present study, exploiting the attributes and structural parameters of the aircraft to be assessed as input to determine the degree of membership that pertains to the commonality sub-interval as the commonality indicator.Then the BP(Back Propagation) neural network algorithm is adopted to establish the relationship between the common index and the decrease rate of the R&D cost of derivative models. The model employs over a dozen typical civil aircraft models(e.g., Boeing, Airbus, and Bombardier) as the sample data for network learning training to build a mature neural network model for estimating the R&D cost of novel derivative models. As revealed from the comparative analysis on the calculated results of the samples, the estimated results of the model given the effects of commonality in the present study exhibit higher estimation accuracy and value for future work.
文摘Component commonality has been cited as a powerful approach for manufacturers to cope with increased component proliferation and to control inventory costs. To fully realize its potential benefits, one needs a clear understanding of its impacts on the system. In this paper, the feasibility of using a simulation model to provide a systematic perspective for manufacturing firms to implement a commonality strategy is demonstrated. Alternative commonality strategies including the stage of employing commonality and the allocation policies are simulated. Several interesting results on effects of commonality, allocation policies, and optimal solutions are obtained. We then summarize qualitative insights and managerial implications into the component commonality design and implementation, and inventory management in a general multi-stage assembly system.
文摘This paper presents a systematic approach to estimate the value of commonality in products that involve multiple stage assemblies. In particular, the inventory savings are quantified with a mathematical model. The purpose is to assist product deisgn teams to make rational decisions in assigning unique parts or pursuing component standardization. In order to enhance the usability of the model, approximations are made to simplify the model and calculations.
文摘BACKGROUND Pancreaticobiliary maljunction(PBM)is a rare congenital abnormality in pancreaticobiliary duct development.PBM is commonly found in children,and it often leads to acute pancreatitis and other diseases as a result of pancreaticobiliary reflux.Roux-en-Y choledochojejunostomy is a common surgical method for the treatment of PBM,but there are several associated complications that may occur after this operation.CASE SUMMARY The patient,a 12-year-old female,was hospitalized nearly 20 times in 2021 for recurrent acute pancreatitis.In 2022,she was diagnosed with PBM and underwent laparoscopic common bile duct resection and Roux-en-Y choledochojejunostomy in a tertiary hospital.In the first year after surgery,the patient had more than 10 recurrent acute pancreatitis episodes.After undergoing abdominal computed tomography and other examinations,she was diagnosed with“residual bile duct stones and recurrent acute pancreatitis”.On January 30,2024,the patient was admitted to our hospital due to recurrent upper abdominal pain and was cured through endoscopic retrograde cholangiopancreatography.CONCLUSION This article reports a case of a child with distal residual common bile duct stones and recurrent acute pancreatitis after Roux-en-Y choledochojejunostomy for PBM.The patient was cured through endoscopic retrograde cholangiopancreatography.
基金Supported by the National Natural Science Foundation of China(12001249)the Natural Science Foundation of Jiangxi Province(20232BAB211004)the Educational Commission Science Programm of Jiangxi Province(GJJ2200523)。
文摘In this paper,we establish common fixed point theorems for expansive map?pings on b-metric-like space and coincidence point for f-weakly isotone increasing mappings in partially ordered b-metric-like space.The main results generalize and extend several well-known comparable results from the existing literature.Moreover,some examples are provided to illustrate the main results.
文摘The recent rapid development in information systems （ISs） has resulted in a critical need for integration and interoperability between heterogeneous ISs in various domains, using specific commonalities. However, stovepipe systems have been caused due to inconsistencies in planning IS architecture among stakeholders. So far, there has been no research on an enterprise architecture framework （EAF） that can satisfy with the coefficient factors of system architecture （SA） and enterprise architecture （EA）. This paper proposes a new EAF that can resolve the problems inherent in existing legacy EAFs and their features. EAFoC （Enterprise Architecture Framework based on Commonality） is based on commonality that can be satisfied as the coefficient factors in both SA and EA within a common information technology （IT） domain. Thus, it should be possible to integrate an established heterogeneous framework for each stakeholder＇s view. Consequently, the most important contribution of this paper is to establish the appropriate EAFoC for the development of consistent IS architecture, smooth communication among stakeholders, systematic integration management of diversified and complicated new IT technologies, interoperability among heterogeneous ISs, and reusability based on commonality with other platforms.
基金Supported by Scientific Research Platform Project of Putuo District,Shanghai(2024QX04).
文摘[Objectives]To investigate the antibacterial mechanism of Common Cnidium Fruit using network pharmacology.[Methods]Active components and targets of Common Cnidium Fruit were screened and obtained using the TCMSP database and HIT2.0 database.The collected targets were intersected with antibacterial/bacteriostatic targets obtained from the GeneCards database and OMIM database to identify the antibacterial/bacteriostatic targets of Common Cnidium Fruit.The active component-target network diagram of Common Cnidium Fruit was constructed using Cytoscape software and topological analysis was performed.GO enrichment analysis was performed on the target genes using the DAVID database.[Results]Screening yielded 25 active components of Common Cnidium Fruit,corresponding to 77 targets.Analysis identified 25 core antibacterial/bacteriostatic targets for Common Cnidium Fruit.Network analysis indicated that Common Cnidium Fruit may exert antibacterial/bacteriostatic effects through active components such asβ-sitosterol,stigmasterol,and xanthoxylin,while activating the body's immune regulatory functions by acting on targets including CASP3,PTGS2,BCL2,JUN,and ESR1.[Conclusions]Common Cnidium Fruit may exert antibacterial/bacteriostatic effects through multiple pathways via a mechanism involving multiple components,multiple targets,and multiple pathways.
基金Supported by the Ke Qiao Science and Technology Plan Projects,No.2022KZ70.
文摘BACKGROUND At present,there are few studies on the risk factors for bile leakage after laparoscopic common bile duct exploration(LCBDE)for older patients with choledocholithiasis.AIM To identify the potential risk factors for bile leakage after LCBDE in older patients.METHODS A retrospective,single-center observational analysis was performed on patients aged≥70 years with choledocholithiasis treated by LCBDE who were admitted to our center between January 2011 and August 2022.The included patients were divided into non-bile leakage and bile leakage groups.Risk factors were determined by analyzing the observation indicators.RESULTS Seventy older patients with choledocholithiasis who underwent LCBDE were included.Univariate analysis showed that positive culture of bile bacteria was a risk factor for bile leakage after LCBDE(P<0.05).We further analyzed the bile bacteria,and univariate analysis showed that Enterococcus faecalis(E.faecalis)(P<0.05)and Pseudomonas aeruginosa(P<0.05)were associated with an increased risk of postoperative bile leakage in older patients(P<0.05).Multivariate analysis showed that E. faecalis was an independent risk factor for postoperative bile leakage in older patients (P < 0.05). Theresults of antibiotic sensitivity analysis showed that E. faecalis had 100% susceptibility to penicillin, ampicillin,linezolid, vancomycin, and furantoin.CONCLUSIONE. faecalis-associated biliary tract infection is an independent risk factor for bile leakage after LCBDE in olderpatients with choledocholithiasis. We suggest coverage with antibiotics to which E. faecalis is sensitive.
基金Supported by Shenzhen Science and Technology Program Project,No.JCYJ20220530145006013.
文摘BACKGROUND Laparoscopic cholecystectomy(LC)and laparoscopic common bile duct exploration(LCBDE)are widely used in gallbladder and biliary tract diseases.During these procedures,vessels or tissues are commonly ligated using clips.However,postoperative migration of clips to the common bile duct(CBD)or Ttube sinus tract is an overlooked complication of laparoscopic biliary surgery.Previously,most reported cases of postoperative clip migration involved metal clips,with only a few cases involving Hem-o-lok clips and review of the literature.CASE SUMMARY This report describes two cases in which Hem-o-lok clips migrated into the CBD and the T-tube sinus tract following laparoscopic surgery.Case 1 is a 68-year-old female admitted due to abdominal discomfort,and two Hem-o-lok clips were found to have migrated into the CBD 17 months after LC and LCBDE with T-tube drainage,and were removed using a stone extraction balloon.The patient was discharged smoothly after recovery.Case 2 is a 74-year-old male who underwent LC and LCBDE with T-tube drainage and laparoscopic biliary tract basket stone extraction.Nine weeks postoperatively,following T-tube removal,a Hem-o-lok clip was found in the sinus tract,and was extracted from the T-tube sinus tract.The patient recovered smoothly postoperatively.This study also reviews the literature from 2013 to July 2024 on using Hem-o-lok clips in LC and/or LCBDE treatment of gallbladder and biliary diseases and the postoperative migration of these clips into the CBD,T-tube sinus tract,or duodenum.CONCLUSION In patients with a history of LC and/or LCBDE,clip migration should be considered as a differential diagnosis.
基金supported by the National Natural Science Foundation of China(32241045,32241046,32241038)the Major Special Science and Technology Projects in Shanxi Province(202101140601027)+3 种基金Shanxi Provincial Agricultural Key Technologies Breakthrough Project(NYGG01)Doctoral Research Starting Project at Shanxi Agricultural University(2024BQ77)the National Key Research and Development Program of China(2023YFD1202705/2023YFD120270503,2023YFD1202703/2023YFD1202703-4)Shanxi HouJi Laboratory Self-proposed Research Project(202304010930003/202304010930003-03).
文摘Common bean(Phaseolus vulgaris L.)is a vital source of protein and essential nutrients for human consumption and plays a key role in sustainable agriculture due to its nitrogen-fixing ability(Nadeem et al.,2021).Kidney beans,a subcategory of dry common beans,are highly valued for their rich protein,dietary fiber,low fat content,and various trace elements(Garcia-Cordero et al.,2021).Despite the release of several de novo genome assemblies(Goodstein et al.,2012;Schmutz et al.,2014;Vlasova et al.,2016;Cortinovis et al.,2024),existing common bean genomes remain incomplete,particularly in complex regions such as centromeres and telomeres,limiting a comprehensive understanding of the genomic landscape.
文摘I have a good friend named Jeff.We are both in Grade Seven and have been close friends since the beginning of this term.Jeff is tall and always wears a warm smile on his face.He is really friendly and kind.We have many things in common.
文摘The common cold is caused by a large range of respiratory viruses and is the most common disease of mankind. There is a great need for a prophylactic treatment for colds. Specific antiviral treatments are only effective against one group of viruses and there is a need for a non-specific treatment that can be used against all respiratory viruses. Carrageenan is a general term used to describe a range of sulfated polysaccharides extracted from edible seaweeds. Large polyanionic molecules such as carrageenan have been shown to have antiviral activity against a wide range of viruses in vitro. The strong anionic charge of carrageenan attracts and traps viruses that have positively charged areas on their surface. The trapped viruses are then unable to infect epithelial cells. Iota-carrageenan exerts its’ antiviral activity by physical means due to its high anionic charge and it does not have any pharmacological properties and therefore does not have any toxicology or known side effects from treatment. Iota-carrageenan does not have any taste or smell and, when used as a nasal spray, does not have any adverse effects. Iota-carrageenan is an ideal prophylactic treatment for the common cold and is safe for use in children. Treatment of common cold with iota-carrageenan has to date been studied in five placebo-controlled clinical trials and these trials support both efficacy as a prophylactic treatment for colds and the safety and tolerability of iota-carrageenan.
