Your comments are welcome!Please feel free to contact us with your personal stories or vivid pictures!Address:24 Baiwanzhuang St.,Xicheng Dist.,Beijing,100037 E-mail:chinatodaynews@aliyun.com.
The editors of International Journal of Ophthalmology gratefully acknowledge the members of IJO Editorial Board and reviewers from 51 countries and regions who participated in the peer-reviews and provided their valua...The editors of International Journal of Ophthalmology gratefully acknowledge the members of IJO Editorial Board and reviewers from 51 countries and regions who participated in the peer-reviews and provided their valuable comments between Nov.1st,2024 and Oct.31st,2025.They volunteer their valuable time and expertise,and without them we would not maintain the necessary quality expected of the journal.We apologize if we have inadvertently missed a reviewer’s name off this list.展开更多
Your comments are welcome!Please feel free to contact us with your personal stories or vivid pictures!Address:24 Baiwanzhuang St.,Xicheng Dist.,Beijing,100037 E-mail:chinatodaynews@aliyun.com.
Your comments are welcome!Please feel free to contact us with your personal stories or vivid pictures!Address:24 Baiwanzhuang St.,Xicheng Dist.,Beijing,100037 E-mail:chinatodaynews@aliyun.com.
Your comments are welcome!Please feel free to contact us with your personal stories or vivid pictures!Address:24 Baiwanzhuang St.,Xicheng Dist.,Beijing,100037 E-mail:chinatodaynews@aliyun.com。
In this article we commented on an article published recently by Jiao et al.This retrospective study confirmed that the triple therapy of transarterial chemoembolization(TACE)combined with programmed death protein lig...In this article we commented on an article published recently by Jiao et al.This retrospective study confirmed that the triple therapy of transarterial chemoembolization(TACE)combined with programmed death protein ligand 1 inhibitors and molecular targeted therapy can significantly reverse TACE resistance in advanced hepatocellular carcinoma.Compared with TACE alone,the triple therapy reduced the resistance rate from 38.8%to 9.7%and increased the median progression-free survival and median overall survival by 92.3%and 26.8%,respectively.TACE induces tumor antigen release and upregulates programmed death protein ligand 1,activating the effect of immune checkpoint inhibitors while molecular targeted therapy inhibits postembolization vascular regeneration,forming a dynamic synergistic network of embolization-immune activation-vascular inhibition.The maximum tumor diameter,capsule loss,and bilateral distribution were identified as independent predictors.This study provided level I evidence and promoted the transformation of advanced hepatocellular carcinoma treatment from single local intervention to an integrated model of local control-systemic treatment.In the future it will be necessary to analyze the dynamic evolution rules of the tumor microenvironment through crossomics strategies,further explore biomarkers,optimize treatment sequences,and conduct multicenter prospective trials to verify long-term survival benefits and guide the optimization of individualized sequential treatment.展开更多
Recently,Jayabalan et al published an important study.The authors defined the liver outcome score as a novel biomarker for predicting liver-related mortality in patients with autoimmune hepatitis-primary biliary chola...Recently,Jayabalan et al published an important study.The authors defined the liver outcome score as a novel biomarker for predicting liver-related mortality in patients with autoimmune hepatitis-primary biliary cholangitis overlap syndrome.After thoroughly reviewing their work,we offer insights that primarily relate to their study design to enhance the medical community’s understanding of this complex disease.展开更多
对于躯体化障碍，目前有两种诊断标准：一种是美国精神病学学会《精神障碍诊断与统计手册第4版》（Diagnostic and Statistical Manual of Mental Disorders，DSM—IV）”。的诊断标准，一种是《国际疾病分类》第10版（International Cl...对于躯体化障碍，目前有两种诊断标准：一种是美国精神病学学会《精神障碍诊断与统计手册第4版》（Diagnostic and Statistical Manual of Mental Disorders，DSM—IV）”。的诊断标准，一种是《国际疾病分类》第10版（International Classification of Diseases，ICD-10）的诊断要点（笔者按，展开更多
文摘Your comments are welcome!Please feel free to contact us with your personal stories or vivid pictures!Address:24 Baiwanzhuang St.,Xicheng Dist.,Beijing,100037 E-mail:chinatodaynews@aliyun.com.
文摘The editors of International Journal of Ophthalmology gratefully acknowledge the members of IJO Editorial Board and reviewers from 51 countries and regions who participated in the peer-reviews and provided their valuable comments between Nov.1st,2024 and Oct.31st,2025.They volunteer their valuable time and expertise,and without them we would not maintain the necessary quality expected of the journal.We apologize if we have inadvertently missed a reviewer’s name off this list.
文摘Your comments are welcome!Please feel free to contact us with your personal stories or vivid pictures!Address:24 Baiwanzhuang St.,Xicheng Dist.,Beijing,100037 E-mail:chinatodaynews@aliyun.com.
文摘Your comments are welcome!Please feel free to contact us with your personal stories or vivid pictures!Address:24 Baiwanzhuang St.,Xicheng Dist.,Beijing,100037 E-mail:chinatodaynews@aliyun.com.
文摘Your comments are welcome!Please feel free to contact us with your personal stories or vivid pictures!Address:24 Baiwanzhuang St.,Xicheng Dist.,Beijing,100037 E-mail:chinatodaynews@aliyun.com。
基金Supported by the National Natural Science Foundation of China,No.82404058Shanghai Municipal Commission of Health and Family Planning,No.2024ZZ2049Beijing Xisike Clinical Oncology Research Foundation,No.Y-HS202401-0011.
文摘In this article we commented on an article published recently by Jiao et al.This retrospective study confirmed that the triple therapy of transarterial chemoembolization(TACE)combined with programmed death protein ligand 1 inhibitors and molecular targeted therapy can significantly reverse TACE resistance in advanced hepatocellular carcinoma.Compared with TACE alone,the triple therapy reduced the resistance rate from 38.8%to 9.7%and increased the median progression-free survival and median overall survival by 92.3%and 26.8%,respectively.TACE induces tumor antigen release and upregulates programmed death protein ligand 1,activating the effect of immune checkpoint inhibitors while molecular targeted therapy inhibits postembolization vascular regeneration,forming a dynamic synergistic network of embolization-immune activation-vascular inhibition.The maximum tumor diameter,capsule loss,and bilateral distribution were identified as independent predictors.This study provided level I evidence and promoted the transformation of advanced hepatocellular carcinoma treatment from single local intervention to an integrated model of local control-systemic treatment.In the future it will be necessary to analyze the dynamic evolution rules of the tumor microenvironment through crossomics strategies,further explore biomarkers,optimize treatment sequences,and conduct multicenter prospective trials to verify long-term survival benefits and guide the optimization of individualized sequential treatment.
基金Supported by The Key Research and Development Project of the Science and Technology Department of Sichuan Province,China,No.2023YFS0280The High-Level Research Initiation Fund of The First Affiliated Hospital of Chengdu Medical College,China,No.CYFY-GQ43.
文摘Recently,Jayabalan et al published an important study.The authors defined the liver outcome score as a novel biomarker for predicting liver-related mortality in patients with autoimmune hepatitis-primary biliary cholangitis overlap syndrome.After thoroughly reviewing their work,we offer insights that primarily relate to their study design to enhance the medical community’s understanding of this complex disease.
文摘对于躯体化障碍，目前有两种诊断标准：一种是美国精神病学学会《精神障碍诊断与统计手册第4版》（Diagnostic and Statistical Manual of Mental Disorders，DSM—IV）”。的诊断标准，一种是《国际疾病分类》第10版（International Classification of Diseases，ICD-10）的诊断要点（笔者按，
