Membrane-assisted antisolvent crystallization(MAAC)is a separation process that allows for precise regulation of the crystallization process in pharmaceutical,finechemical engineering,energy chemistry,etc.After decade...Membrane-assisted antisolvent crystallization(MAAC)is a separation process that allows for precise regulation of the crystallization process in pharmaceutical,finechemical engineering,energy chemistry,etc.After decades of development,the current MAAC engineering lacks highly robust specialized instruments,which limits the further industrial application of the MAAC process.Herein,to guide the design and optimization of the advanced MAAC instrument(DUT-iMC),we developed a parameter evaluation strategy based on cold model experiments.This approach utilizes the average particle size variation rate and the counts variation rate to characterize crystal size changes.The layout of the internal membrane module in DUT-iMC and the arrangement of the conveying pipeline were optimized.This improvement enhanced particle conveying characteristics,promoting more efficienttransport and circulation within the module.The advanced MAAC instrument substantially automates the production process,and the internal probes accurately monitor and record process variables,allowing for precise regulation of crystal size and morphology.The optimal operating range was expanded by 150%compared to the laboratory instrument.The range of shell side flow rate options increased by 50%,and the production time can be shortened by up to 30%.This paper provides ideas and guidance for the industrialization of MAAC processes and the development of related instruments.展开更多
Pressure oscillation in solid rocket motor is believed to be the results of the interaction between the flow instability and the acoustics of combustion chamber.Several reasonable and necessary hypothesizes are given ...Pressure oscillation in solid rocket motor is believed to be the results of the interaction between the flow instability and the acoustics of combustion chamber.Several reasonable and necessary hypothesizes are given to establish an equation to describe this coupling.A cold flow motor called CVS60D(corner vortex shedding 60°)was designed to study the flow-acoustic coupling based on theoretical analysis.Experimental investigations were carried out to determine the acoustics of CVS60D.Corner vortex shedding is generated at the backward facing step which is designed similar to the geometry of the motor with finocyl propellant after the burnout of its fins.A pintle was used to modify the velocity in the duct to change the frequency of vortex shedding.It is found that large amplitude pressure oscillation occurs when the pintle moves to a range of specific position,which indicates that the frequency of vortex shedding is close to one order of acoustic modes of combustion chamber.The amplitude of pressure oscillation changes as the pintle moves.展开更多
Based on diagnostic results,a numerical study is made of the processes of Australian cold air activity affecting East Asian summer monsoon by using Kuo-Qian P-σ incorporated coordinate five-layer primitive equation s...Based on diagnostic results,a numerical study is made of the processes of Australian cold air activity affecting East Asian summer monsoon by using Kuo-Qian P-σ incorporated coordinate five-layer primitive equation spherical band model.Analysis is done of the response to the Southern Hemisphere circulation with and without cold air activity in Australia of the flow,rainfall and diabatic heating fields in the monsoon area of Asia,especially,East Asia,with special attention to the intensification and northward march of the monsoon due to the activity.It is found that the processes for the effect transmission are very analogous to the meridional propagation of quasi-40-day oscillation,together with the meridional wind disturbance showing south-north travel and the flow/rainfall fields exhibitirg corresponding movement in this direction,only with a 12-day lag.展开更多
基金financial contribution from the National Natural Science Foundation of China(22021005,22378041)Supporting Plan of Scientificand Technology Innovative Talents in Dalian(2023RJ001)Central Guidance on Local Science and Technology Development Fund of Liaoning Province(2025040052-JH6/1011)。
文摘Membrane-assisted antisolvent crystallization(MAAC)is a separation process that allows for precise regulation of the crystallization process in pharmaceutical,finechemical engineering,energy chemistry,etc.After decades of development,the current MAAC engineering lacks highly robust specialized instruments,which limits the further industrial application of the MAAC process.Herein,to guide the design and optimization of the advanced MAAC instrument(DUT-iMC),we developed a parameter evaluation strategy based on cold model experiments.This approach utilizes the average particle size variation rate and the counts variation rate to characterize crystal size changes.The layout of the internal membrane module in DUT-iMC and the arrangement of the conveying pipeline were optimized.This improvement enhanced particle conveying characteristics,promoting more efficienttransport and circulation within the module.The advanced MAAC instrument substantially automates the production process,and the internal probes accurately monitor and record process variables,allowing for precise regulation of crystal size and morphology.The optimal operating range was expanded by 150%compared to the laboratory instrument.The range of shell side flow rate options increased by 50%,and the production time can be shortened by up to 30%.This paper provides ideas and guidance for the industrialization of MAAC processes and the development of related instruments.
基金Sponsored by the National Nature Science Foundation of China(10602047)
文摘Pressure oscillation in solid rocket motor is believed to be the results of the interaction between the flow instability and the acoustics of combustion chamber.Several reasonable and necessary hypothesizes are given to establish an equation to describe this coupling.A cold flow motor called CVS60D(corner vortex shedding 60°)was designed to study the flow-acoustic coupling based on theoretical analysis.Experimental investigations were carried out to determine the acoustics of CVS60D.Corner vortex shedding is generated at the backward facing step which is designed similar to the geometry of the motor with finocyl propellant after the burnout of its fins.A pintle was used to modify the velocity in the duct to change the frequency of vortex shedding.It is found that large amplitude pressure oscillation occurs when the pintle moves to a range of specific position,which indicates that the frequency of vortex shedding is close to one order of acoustic modes of combustion chamber.The amplitude of pressure oscillation changes as the pintle moves.
基金National Natural Science Foundation of ChinaState Meteorological Administration Monsoon Research Funds
文摘Based on diagnostic results,a numerical study is made of the processes of Australian cold air activity affecting East Asian summer monsoon by using Kuo-Qian P-σ incorporated coordinate five-layer primitive equation spherical band model.Analysis is done of the response to the Southern Hemisphere circulation with and without cold air activity in Australia of the flow,rainfall and diabatic heating fields in the monsoon area of Asia,especially,East Asia,with special attention to the intensification and northward march of the monsoon due to the activity.It is found that the processes for the effect transmission are very analogous to the meridional propagation of quasi-40-day oscillation,together with the meridional wind disturbance showing south-north travel and the flow/rainfall fields exhibitirg corresponding movement in this direction,only with a 12-day lag.
