期刊文献+
共找到987,489篇文章
< 1 2 250 >
每页显示 20 50 100
OptoGPT code, model, and datasets made public
1
《Opto-Electronic Advances》 2025年第6期1-1,共1页
The article entitled with OptoGPT:A foundation model for inverse design in optical multilayer thin film structures1,with doi:10.29026/oea.2024.240062,published in No.7,Vol.7,2024 of Opto-Electronic Advances,has attrac... The article entitled with OptoGPT:A foundation model for inverse design in optical multilayer thin film structures1,with doi:10.29026/oea.2024.240062,published in No.7,Vol.7,2024 of Opto-Electronic Advances,has attracted attention from many researchers.As a result,the authors received many requests on the possibility sharing their code,model,and dataset in the mentioned work.To facilitate the needs of the research community,the authors decide to make the code,model,and datasets of OptoGPT public,enabling broader utilization and further development of enhanced models. 展开更多
关键词 foundation model inverse design optogpt model optical multilayer thin film structures code
在线阅读 下载PDF
Lightweight Deep Learning Model and Novel Dataset for Restoring Damaged Barcodes and QR Codes in Logistics Applications
2
作者 Tarek Muallim Haluk Kucuk +1 位作者 Muhammet Bareket Metin Kahraman 《Computer Modeling in Engineering & Sciences》 2025年第6期3557-3581,共25页
This study introduces a lightweight deep learning model and a novel synthetic dataset designed to restore damaged one-dimensional(1D)barcodes and Quick Response(QR)codes,addressing critical challenges in logistics ope... This study introduces a lightweight deep learning model and a novel synthetic dataset designed to restore damaged one-dimensional(1D)barcodes and Quick Response(QR)codes,addressing critical challenges in logistics operations.The proposed solution leverages an efficient Pix2Pix-based framework,a type of conditional Generative Adversarial Network(GAN)optimized for image-to-image translation tasks,enabling the recovery of degraded barcodes and QR codes with minimal computational overhead.A core contribution of this work is the development of a synthetic dataset that simulates realistic damage scenarios frequently encountered in logistics environments,such as low contrast,misalignment,physical wear,and environmental interference.By training on this diverse and realistic dataset,the model demonstrates exceptional performance in restoring readability and decoding accuracy.The lightweight architecture,featuring a U-Net-based encoder-decoder with separable convolutions,ensures computational efficiency,making the approach suitable for real-time deployment on embedded and resource-constrained devices commonly used in logistics systems.Experimental results reveal significant improvements:QR code decoding ratios increased from 14%to 99%on training data and from 15%to 68%on validation data,while 1D barcode decoding ratios improved from 7%to 73%on training data and from 9%to 44%on validation data.By providing a robust,resource-efficient solution for restoring damaged barcodes and QR codes,this study offers practical advancements for enhancing the reliability of automated scanning systems in logistics operations,particularly under challenging conditions. 展开更多
关键词 BARcode quick response code RESTORATION applied deep learning
在线阅读 下载PDF
System Modeling and Deep Learning-Based Security Analysis of Uplink NOMA Relay Networks with IRS and Fountain Codes
3
作者 Phu Tran Tin Minh-Sang Van Nguyen +2 位作者 Quy-Anh Bui Agbotiname Lucky Imoize Byung-Seo Kim 《Computer Modeling in Engineering & Sciences》 2025年第8期2521-2543,共23页
Digital content such as games,extended reality(XR),and movies has been widely and easily distributed over wireless networks.As a result,unauthorized access,copyright infringement by third parties or eavesdroppers,and ... Digital content such as games,extended reality(XR),and movies has been widely and easily distributed over wireless networks.As a result,unauthorized access,copyright infringement by third parties or eavesdroppers,and cyberattacks over these networks have become pressing concerns.Therefore,protecting copyrighted content and preventing illegal distribution in wireless communications has garnered significant attention.The Intelligent Reflecting Surface(IRS)is regarded as a promising technology for future wireless and mobile networks due to its ability to reconfigure the radio propagation environment.This study investigates the security performance of an uplink Non-Orthogonal Multiple Access(NOMA)system integrated with an IRS and employing Fountain Codes(FCs).Specifically,two users send signals to the base station at separate distances.A relay receives the signal from the nearby user first and then relays it to the base station.The IRS receives the signal from the distant user and reflects it to the relay,which then sends the reflected signal to the base station.Furthermore,a malevolent eavesdropper intercepts both user and relay communications.We construct mathematical equations for Outage Probability(OP),throughput,diversity evaluation,and Interception Probability(IP),offering quantitative insights to assess system security and performance.Additionally,OP and IP are analyzed using a Deep Neural Network(DNN)model.A deeper comprehension of the security performance of the IRS-assisted NOMA systemin signal transmission is provided by Monte Carlo simulations,which are also carried out to confirm the theoretical conclusions. 展开更多
关键词 Copyright management deep neural network fountain codes intelligent reflecting surface non-orthogonal multiple access physical layer security UPLINK
在线阅读 下载PDF
An Online Judgement System Based on Code-generating Large Model
4
作者 Xudong Lu Zaixuan Wang +3 位作者 He Zhou Chen Yu Lizhen Cui Wei Guo 《计算机教育》 2025年第3期122-129,共8页
For computer science majors in higher education institutions,programming courses are one of the most important professional foundation courses.Proficiency in independent programming skills is of great help to the stud... For computer science majors in higher education institutions,programming courses are one of the most important professional foundation courses.Proficiency in independent programming skills is of great help to the study of subsequent courses and the personal development of students.In the teaching process of programming courses,online judgement systems are often used to improve students’programming level.Traditional online judgement systems lack guidance for students,and it is often difficult for inexperienced students to find and correct errors in their codes by themselves.We propose an online judgement system that integrates a large model of error correction to help students find errors and improve their programming skills. 展开更多
关键词 Online judgement system code-generating large model AI assistant
在线阅读 下载PDF
An effective method for generating crystal structures based on the variational autoencoder and the diffusion model
5
作者 Chen Chen Jinzhou Zheng +3 位作者 Chaoqin Chu Qinkun Xiao Chaozheng He Xi Fu 《Chinese Chemical Letters》 2025年第4期461-466,共6页
Two dimensional(2D) materials based on boron and carbon have attracted wide attention due to their unique properties. BC compounds have rich active sites and diverse chemical coordination, showing great potential in o... Two dimensional(2D) materials based on boron and carbon have attracted wide attention due to their unique properties. BC compounds have rich active sites and diverse chemical coordination, showing great potential in optoelectronic applications. However, due to the limitation of calculation and experimental conditions, it is still a challenging task to predict new 2D BC monolayer materials. Specifically, we utilized Crystal Diffusion Variational Autoencoder(CDVAE) and pre-trained Materials Graph Neural Network with 3-Body Interactions(M3GNet) model to generate novel and stable BCP materials. Each crystal structure was treated as a high-dimensional vector, where the encoder extracted lattice information and element coordinates, mapping the high-dimensional data into a low-dimensional latent space. The decoder then reconstructed the latent representation back into the original data space. Additionally, our designed attribute predictor network combined the advantages of dilated convolutions and residual connections,effectively increasing the model's receptive field and learning capacity while maintaining relatively low parameter count and computational complexity. By progressively increasing the dilation rate, the model can capture features at different scales. We used the DFT data set of about 1600 BCP monolayer materials to train the diffusion model, and combined with the pre-trained M3GNet model to screen the best candidate structure. Finally, we used DFT calculations to confirm the stability of the candidate structure.The results show that the combination of generative deep learning model and attribute prediction model can help accelerate the discovery and research of new 2D materials, and provide effective methods for exploring the inverse design of new two-dimensional materials. 展开更多
关键词 Deep generative model BCP monolayer Inverse design CDVAE DFT
原文传递
Multi-Head Encoder Shared Model Integrating Intent and Emotion for Dialogue Summarization
6
作者 Xinlai Xing Junliang Chen +2 位作者 Xiaochuan Zhang Shuran Zhou Runqing Zhang 《Computers, Materials & Continua》 2025年第2期2275-2292,共18页
In task-oriented dialogue systems, intent, emotion, and actions are crucial elements of user activity. Analyzing the relationships among these elements to control and manage task-oriented dialogue systems is a challen... In task-oriented dialogue systems, intent, emotion, and actions are crucial elements of user activity. Analyzing the relationships among these elements to control and manage task-oriented dialogue systems is a challenging task. However, previous work has primarily focused on the independent recognition of user intent and emotion, making it difficult to simultaneously track both aspects in the dialogue tracking module and to effectively utilize user emotions in subsequent dialogue strategies. We propose a Multi-Head Encoder Shared Model (MESM) that dynamically integrates features from emotion and intent encoders through a feature fusioner. Addressing the scarcity of datasets containing both emotion and intent labels, we designed a multi-dataset learning approach enabling the model to generate dialogue summaries encompassing both user intent and emotion. Experiments conducted on the MultiWoZ and MELD datasets demonstrate that our model effectively captures user intent and emotion, achieving extremely competitive results in dialogue state tracking tasks. 展开更多
关键词 Dialogue summaries dialogue state tracking emotion recognition task-oriented dialogue system pre-trained language model
在线阅读 下载PDF
Ecological Dynamics of a Logistic Population Model with Impulsive Age-selective Harvesting
7
作者 DAI Xiangjun JIAO Jianjun 《应用数学》 北大核心 2026年第1期72-79,共8页
In this paper,we establish and study a single-species logistic model with impulsive age-selective harvesting.First,we prove the ultimate boundedness of the solutions of the system.Then,we obtain conditions for the asy... In this paper,we establish and study a single-species logistic model with impulsive age-selective harvesting.First,we prove the ultimate boundedness of the solutions of the system.Then,we obtain conditions for the asymptotic stability of the trivial solution and the positive periodic solution.Finally,numerical simulations are presented to validate our results.Our results show that age-selective harvesting is more conducive to sustainable population survival than non-age-selective harvesting. 展开更多
关键词 The logistic population model Selective harvesting Asymptotic stability EXTINCTION
在线阅读 下载PDF
Modeling of Precipitation over Africa:Progress,Challenges,and Prospects
8
作者 A.A.AKINSANOLA C.N.WENHAJI +21 位作者 R.BARIMALALA P.-A.MONERIE R.D.DIXON A.T.TAMOFFO M.O.ADENIYI V.ONGOMA I.DIALLO M.GUDOSHAVA C.M.WAINWRIGHT R.JAMES K.C.SILVERIO A.FAYE S.S.NANGOMBE M.W.POKAM D.A.VONDOU N.C.G.HART I.PINTO M.KILAVI S.HAGOS E.N.RAJAGOPAL R.K.KOLLI S.JOSEPH 《Advances in Atmospheric Sciences》 2026年第1期59-86,共28页
In recent years,there has been an increasing need for climate information across diverse sectors of society.This demand has arisen from the necessity to adapt to and mitigate the impacts of climate variability and cha... In recent years,there has been an increasing need for climate information across diverse sectors of society.This demand has arisen from the necessity to adapt to and mitigate the impacts of climate variability and change.Likewise,this period has seen a significant increase in our understanding of the physical processes and mechanisms that drive precipitation and its variability across different regions of Africa.By leveraging a large volume of climate model outputs,numerous studies have investigated the model representation of African precipitation as well as underlying physical processes.These studies have assessed whether the physical processes are well depicted and whether the models are fit for informing mitigation and adaptation strategies.This paper provides a review of the progress in precipitation simulation overAfrica in state-of-the-science climate models and discusses the major issues and challenges that remain. 展开更多
关键词 RAINFALL MONSOON climate modeling CORDEX CMIP6 convection-permitting models
在线阅读 下载PDF
Design optimization and FEA of B-6 and B-7 levels ballistics armor:A modelling approach
9
作者 Muhammad Naveed CHU Jinkui +1 位作者 Atif Ur Rehman Arsalan Hyder 《大连理工大学学报》 北大核心 2026年第1期66-77,共12页
Utilizing finite element analysis,the ballistic protection provided by a combination of perforated D-shaped and base armor plates,collectively referred to as radiator armor,is evaluated.ANSYS Explicit Dynamics is empl... Utilizing finite element analysis,the ballistic protection provided by a combination of perforated D-shaped and base armor plates,collectively referred to as radiator armor,is evaluated.ANSYS Explicit Dynamics is employed to simulate the ballistic impact of 7.62 mm armor-piercing projectiles on Aluminum AA5083-H116 and Steel Secure 500 armors,focusing on the evaluation of material deformation and penetration resistance at varying impact points.While the D-shaped armor plate is penetrated by the armor-piercing projectiles,the combination of the perforated D-shaped and base armor plates successfully halts penetration.A numerical model based on the finite element method is developed using software such as SolidWorks and ANSYS to analyze the interaction between radiator armor and bullet.The perforated design of radiator armor is to maintain airflow for radiator function,with hole sizes smaller than the bullet core diameter to protect radiator assemblies.Predictions are made regarding the brittle fracture resulting from the projectile core′s bending due to asymmetric impact,and the resulting fragments failed to penetrate the perforated base armor plate.Craters are formed on the surface of the perforated D-shaped armor plate due to the impact of projectile fragments.The numerical model accurately predicts hole growth and projectile penetration upon impact with the armor,demonstrating effective protection of the radiator assemblies by the radiator armor. 展开更多
关键词 radiator armor ballistics simulation Johnson-Cook model armor-piercing projectile perforated D-shaped armor plate
在线阅读 下载PDF
Do Higher Horizontal Resolution Models Perform Better?
10
作者 Shoji KUSUNOKI 《Advances in Atmospheric Sciences》 2026年第1期259-262,共4页
Climate model prediction has been improved by enhancing model resolution as well as the implementation of sophisticated physical parameterization and refinement of data assimilation systems[section 6.1 in Wang et al.(... Climate model prediction has been improved by enhancing model resolution as well as the implementation of sophisticated physical parameterization and refinement of data assimilation systems[section 6.1 in Wang et al.(2025)].In relation to seasonal forecasting and climate projection in the East Asian summer monsoon season,proper simulation of the seasonal migration of rain bands by models is a challenging and limiting factor[section 7.1 in Wang et al.(2025)]. 展开更多
关键词 enhancing model resolution refinement data assimilation systems section climate model climate projection higher horizontal resolution seasonal forecasting simulation seasonal migration rain bands model resolution
在线阅读 下载PDF
A medical image segmentation model based on SAM with an integrated local multi-scale feature encoder
11
作者 DI Jing ZHU Yunlong LIANG Chan 《Journal of Measurement Science and Instrumentation》 2025年第3期359-370,共12页
Despite its remarkable performance on natural images,the segment anything model(SAM)lacks domain-specific information in medical imaging.and faces the challenge of losing local multi-scale information in the encoding ... Despite its remarkable performance on natural images,the segment anything model(SAM)lacks domain-specific information in medical imaging.and faces the challenge of losing local multi-scale information in the encoding phase.This paper presents a medical image segmentation model based on SAM with a local multi-scale feature encoder(LMSFE-SAM)to address the issues above.Firstly,based on the SAM,a local multi-scale feature encoder is introduced to improve the representation of features within local receptive field,thereby supplying the Vision Transformer(ViT)branch in SAM with enriched local multi-scale contextual information.At the same time,a multiaxial Hadamard product module(MHPM)is incorporated into the local multi-scale feature encoder in a lightweight manner to reduce the quadratic complexity and noise interference.Subsequently,a cross-branch balancing adapter is designed to balance the local and global information between the local multi-scale feature encoder and the ViT encoder in SAM.Finally,to obtain smaller input image size and to mitigate overlapping in patch embeddings,the size of the input image is reduced from 1024×1024 pixels to 256×256 pixels,and a multidimensional information adaptation component is developed,which includes feature adapters,position adapters,and channel-spatial adapters.This component effectively integrates the information from small-sized medical images into SAM,enhancing its suitability for clinical deployment.The proposed model demonstrates an average enhancement ranging from 0.0387 to 0.3191 across six objective evaluation metrics on BUSI,DDTI,and TN3K datasets compared to eight other representative image segmentation models.This significantly enhances the performance of the SAM on medical images,providing clinicians with a powerful tool in clinical diagnosis. 展开更多
关键词 segment anything model(SAM) medical image segmentation ENcodeR decoder multiaxial Hadamard product module(MHPM) cross-branch balancing adapter
在线阅读 下载PDF
A Predictive Model for the Elastic Modulus of High-Strength Concrete Based on Coarse Aggregate Characteristics
12
作者 LI Liangshun LI Huajian +2 位作者 HUANG Fali YANG Zhiqiang DONG Haoliang 《Journal of Wuhan University of Technology(Materials Science)》 2026年第1期121-137,共17页
To investigate the influence of coarse aggregate parent rock properties on the elastic modulus of concrete,the mineralogical properties and stress-strain curves of granite and dolomite parent rocks,as well as the stre... To investigate the influence of coarse aggregate parent rock properties on the elastic modulus of concrete,the mineralogical properties and stress-strain curves of granite and dolomite parent rocks,as well as the strength and elastic modulus of mortar and concrete prepared with mechanism aggregates of the corresponding lithology,and the stress-strain curves of concrete were investigated.In this paper,a coarse aggregate and mortar matrix bonding assumption is proposed,and a prediction model for the elastic modulus of mortar is established by considering the lithology of the mechanism sand and the slurry components.An equivalent coarse aggregate elastic modulus model was established by considering factors such as coarse aggregate particle size,volume fraction,and mortar thickness between coarse aggregates.Based on the elastic modulus of the equivalent coarse aggregate and the remaining mortar,a prediction model for the elastic modulus of the two and three components of concrete in series and then in parallel was established,and the predicted values differed from the measured values within 10%.It is proposed that the coarse aggregate elastic modulus in highstrength concrete is the most critical factor affecting the elastic modulus of concrete,and as the coarse aggregate elastic modulus increases by 27.7%,the concrete elastic modulus increases by 19.5%. 展开更多
关键词 elastic modulus prediction model MINERALOGICAL influence mechanism
原文传递
Global Stability of Traveling Wavefronts for a Belousov-Zhabotinsky Model with Mixed Nonlocal and Degenerate Diffusions
13
作者 Yuting YANG Guobao ZHANG 《Journal of Mathematical Research with Applications》 2026年第1期87-102,共16页
In this paper,we are concerned with the stability of traveling wavefronts of a Belousov-Zhabotinsky model with mixed nonlocal and degenerate diffusions.Such a system can be used to study the competition among nonlocal... In this paper,we are concerned with the stability of traveling wavefronts of a Belousov-Zhabotinsky model with mixed nonlocal and degenerate diffusions.Such a system can be used to study the competition among nonlocally diffusive species and degenerately diffusive species.We prove that the traveling wavefronts are exponentially stable,when the initial perturbation around the traveling waves decays exponentially as x→-∞,but in other locations,the initial data can be arbitrarily large.The adopted methods are the weighted energy with the comparison principle and squeezing technique. 展开更多
关键词 Belousov-Zhabotinsky model nonlocal diffusion stability comparison principle weighted energy
原文传递
An effective deep-learning prediction of Arctic sea-ice concentration based on the U-Net model
14
作者 Yifan Xie Ke Fan +2 位作者 Hongqing Yang Yi Fan Shengping He 《Atmospheric and Oceanic Science Letters》 2026年第1期34-40,共7页
Current shipping,tourism,and resource development requirements call for more accurate predictions of the Arctic sea-ice concentration(SIC).However,due to the complex physical processes involved,predicting the spatiote... Current shipping,tourism,and resource development requirements call for more accurate predictions of the Arctic sea-ice concentration(SIC).However,due to the complex physical processes involved,predicting the spatiotemporal distribution of Arctic SIC is more challenging than predicting its total extent.In this study,spatiotemporal prediction models for monthly Arctic SIC at 1-to 3-month leads are developed based on U-Net-an effective convolutional deep-learning approach.Based on explicit Arctic sea-ice-atmosphere interactions,11 variables associated with Arctic sea-ice variations are selected as predictors,including observed Arctic SIC,atmospheric,oceanic,and heat flux variables at 1-to 3-month leads.The prediction skills for the monthly Arctic SIC of the test set(from January 2018 to December 2022)are evaluated by examining the mean absolute error(MAE)and binary accuracy(BA).Results showed that the U-Net model had lower MAE and higher BA for Arctic SIC compared to two dynamic climate prediction systems(CFSv2 and NorCPM).By analyzing the relative importance of each predictor,the prediction accuracy relies more on the SIC at the 1-month lead,but on the surface net solar radiation flux at 2-to 3-month leads.However,dynamic models show limited prediction skills for surface net solar radiation flux and other physical processes,especially in autumn.Therefore,the U-Net model can be used to capture the connections among these key physical processes associated with Arctic sea ice and thus offers a significant advantage in predicting Arctic SIC. 展开更多
关键词 Arctic sea-ice concentration Deep-learning prediction U-Net model CFSv2 NorCPM
在线阅读 下载PDF
Tail clamping induces anxiety-like behaviors and visceral hypersensitivity in rat models of non-erosive reflux disease
15
作者 Mi Lv Xin Liu +6 位作者 Kai-Yue Huang Yu-Xi Wang Zheng Wang Li-Li Han Hui Che Lin Lv Feng-Yun Wang 《World Journal of Psychiatry》 2026年第1期356-368,共13页
BACKGROUND Non-erosive reflux disease(NERD),the main gastroesophageal reflux subtype,features reflux symptoms without mucosal damage.Anxiety links to visceral hypersensitivity in NERD,yet mechanisms and animal models ... BACKGROUND Non-erosive reflux disease(NERD),the main gastroesophageal reflux subtype,features reflux symptoms without mucosal damage.Anxiety links to visceral hypersensitivity in NERD,yet mechanisms and animal models are unclear.AIM To establish a translational NERD rat model with anxiety comorbidity via tail clamping and study corticotropin-releasing hormone(CRH)-mediated neuroimmune pathways in visceral hypersensitivity and esophageal injury.METHODS Sprague-Dawley(SD)and Wistar rats were grouped into sham,model,and modified groups(n=10 each).The treatments for the modified groups were as follows:SD rats received ovalbumin/aluminum hydroxide suspension+acid perfusion±tail clamping(40 minutes/day for 7 days),while Wistar rats received fructose water+tail clamping.Esophageal pathology,visceral sensitivity,and behavior were assessed.Serum CRH,calcitonin gene-related peptide(CGRP),5-hydroxytryptamine(5-HT),and mast cell tryptase(MCT)and central amygdala(CeA)CRH mRNA were measured via ELISA and qRT-PCR.RESULTS Tail clamping induced anxiety,worsening visceral hypersensitivity(lower abdominal withdrawal reflex thresholds,P<0.05)and esophageal injury(dilated intercellular spaces and mitochondrial edema).Both models showed raised serum CRH,CGRP,5-HT,and MCT(P<0.01)and CeA CRH mRNA expression(P<0.01).Behavioral tests confirmed anxiety-like phenotypes.NERD-anxiety rats showed clinical-like symptom severity without erosion.CONCLUSION Tail clamping induces anxiety in NERD models,worsening visceral hypersensitivity via CRH neuroimmune dysregulation,offering a translational model and highlighting CRH as a treatment target. 展开更多
关键词 Non-erosive reflux disease Anxiety and depression Animal model Tail-clamping Corticotropin hormones
暂未订购
Processing map for oxide dispersion strengthening Cu alloys based on experimental results and machine learning modelling
16
作者 Le Zong Lingxin Li +8 位作者 Lantian Zhang Xuecheng Jin Yong Zhang Wenfeng Yang Pengfei Liu Bin Gan Liujie Xu Yuanshen Qi Wenwen Sun 《International Journal of Minerals,Metallurgy and Materials》 2026年第1期292-305,共14页
Oxide dispersion strengthened(ODS)alloys are extensively used owing to high thermostability and creep strength contributed from uniformly dispersed fine oxides particles.However,the existence of these strengthening pa... Oxide dispersion strengthened(ODS)alloys are extensively used owing to high thermostability and creep strength contributed from uniformly dispersed fine oxides particles.However,the existence of these strengthening particles also deteriorates the processability and it is of great importance to establish accurate processing maps to guide the thermomechanical processes to enhance the formability.In this study,we performed particle swarm optimization-based back propagation artificial neural network model to predict the high temperature flow behavior of 0.25wt%Al2O3 particle-reinforced Cu alloys,and compared the accuracy with that of derived by Arrhenius-type constitutive model and back propagation artificial neural network model.To train these models,we obtained the raw data by fabricating ODS Cu alloys using the internal oxidation and reduction method,and conducting systematic hot compression tests between 400 and800℃with strain rates of 10^(-2)-10 S^(-1).At last,processing maps for ODS Cu alloys were proposed by combining processing parameters,mechanical behavior,microstructure characterization,and the modeling results achieved a coefficient of determination higher than>99%. 展开更多
关键词 oxide dispersion strengthened Cu alloys constitutive model machine learning hot deformation processing maps
在线阅读 下载PDF
Growing a Rural Future--A young Ugandan channels insights from China’s model villages to build a more resilient,cooperative and forward-looking Busoga
17
作者 LI XIAOYU 《ChinAfrica》 2026年第1期56-57,共2页
In the lush heart of Uganda’s Busoga sub-region,Isaac Imaka is charting a new course for rural development.After seven years in national media,he left the newsroom and stepped into the soil.The former reporter with t... In the lush heart of Uganda’s Busoga sub-region,Isaac Imaka is charting a new course for rural development.After seven years in national media,he left the newsroom and stepped into the soil.The former reporter with the Daily Monitor was driven by the belief that communities like his in Jinja North deserved more than chronic poverty and hand-to-mouth survival. 展开更多
关键词 community resilience Uganda rural development model villages rural future Busoga sub region cooperative development rural journalism
原文传递
Effects of noninvasive brain stimulation on motor functions in animal models of ischemia and trauma in the central nervous system
18
作者 Seda Demir Gereon R.Fink +1 位作者 Maria A.Rueger Stefan J.Blaschke 《Neural Regeneration Research》 2026年第4期1264-1276,共13页
Noninvasive brain stimulation techniques offer promising therapeutic and regenerative prospects in neurological diseases by modulating brain activity and improving cognitive and motor functions.Given the paucity of kn... Noninvasive brain stimulation techniques offer promising therapeutic and regenerative prospects in neurological diseases by modulating brain activity and improving cognitive and motor functions.Given the paucity of knowledge about the underlying modes of action and optimal treatment modalities,a thorough translational investigation of noninvasive brain stimulation in preclinical animal models is urgently needed.Thus,we reviewed the current literature on the mechanistic underpinnings of noninvasive brain stimulation in models of central nervous system impairment,with a particular emphasis on traumatic brain injury and stroke.Due to the lack of translational models in most noninvasive brain stimulation techniques proposed,we found this review to the most relevant techniques used in humans,i.e.,transcranial magnetic stimulation and transcranial direct current stimulation.We searched the literature in Pub Med,encompassing the MEDLINE and PMC databases,for studies published between January 1,2020 and September 30,2024.Thirty-five studies were eligible.Transcranial magnetic stimulation and transcranial direct current stimulation demonstrated distinct strengths in augmenting rehabilitation post-stroke and traumatic brain injury,with emerging mechanistic evidence.Overall,we identified neuronal,inflammatory,microvascular,and apoptotic pathways highlighted in the literature.This review also highlights a lack of translational surrogate parameters to bridge the gap between preclinical findings and their clinical translation. 展开更多
关键词 noninvasive brain stimulation preclinical modeling STROKE transcranial direct current stimulation transcranial magnetic stimulation traumatic brain injury
暂未订购
Risk factors for paternal perinatal depression in Chinese advanced maternal age couples:A regression mixture model
19
作者 Xing Yin Juan Du +1 位作者 Shao-Lian Cai Xing-Qiang Chen 《World Journal of Psychiatry》 2026年第1期267-277,共11页
BACKGROUND Paternal perinatal depression(PPD)is closely associated with maternal mental health challenges,marital strain,and adverse child developmental outcomes.Despite its significant impact,PPD remains under-recogn... BACKGROUND Paternal perinatal depression(PPD)is closely associated with maternal mental health challenges,marital strain,and adverse child developmental outcomes.Despite its significant impact,PPD remains under-recognized in family-centered clinical practice.Concurrently,against the backdrop of rising rates of delayed marriage and China’s Maternity Incentive Policy,the proportion of women giving birth at an advanced maternal age is increasing.Nevertheless,research specifically examining PPD among spouses of older mothers remains critically scarce,both in China and globally.AIM To investigate PPD and its influencing factors in Chinese advanced maternal age families.METHODS This cross-sectional study included 358 participants;it was conducted among fathers of pregnant women of advanced maternal age at five hospitals in the Pearl River Delta region of China from September 2023 to June 2024.Data were collected via a general information questionnaire,the Social Support Rating Scale,and the Edinburgh Postnatal Depression Scale.Latent profile analysis and regression mixture models(RMMs)were adopted to analyze the latent PPD types and factors that influenced PPD.RESULTS The incidence of PPD was 16.48%,and three profiles were identified:Low-symptomatic(175 cases,48.89%),monophasic(140 cases,39.10%),and high-symptomatic(43 cases,12.01%).The RMM analysis revealed that first pregnancy,low income(<¥3000/month),part-time work,and a history of abnormal pregnancy were positively associated with the high-symptomatic type(P<0.05).Conversely,high subjective support and support utilization were negatively associated with the high-symptomatic type compared with the low-symptomatic type(P<0.05).Good couple relationships,high objective and subjective support,and high support utilization were negatively associated with monophasic disorder(P<0.05).CONCLUSION PPD incidence is high among Chinese fathers with advanced maternal age partners,and the characteristics of depression are varied.Healthcare practitioners should prioritize individuals with low levels of social support. 展开更多
关键词 Advanced maternal age Paternal perinatal depression Fathers’mental health Regression mixture model Advanced-age pregnancy Latent profile analysis
暂未订购
Novel therapies for myasthenia gravis:Translational research from animal models to clinical application
20
作者 Benedetta Sorrenti Christian Laurini +4 位作者 Luca Bosco Camilla Mirella Maria Strano Adele Ratti Yuri Matteo Falzone Stefano Carlo Previtali 《Neural Regeneration Research》 2026年第5期1834-1848,共15页
Myasthenia gravis is a chronic autoimmune disorder that affects the neuromuscular junction leading to fluctuating skeletal muscle fatigability. The majority of myasthenia gravis patients have detectable antibodies in ... Myasthenia gravis is a chronic autoimmune disorder that affects the neuromuscular junction leading to fluctuating skeletal muscle fatigability. The majority of myasthenia gravis patients have detectable antibodies in their serum, targeting acetylcholine receptor, muscle-specific kinase, or related proteins. Current treatment for myasthenia gravis involves symptomatic therapy, immunosuppressive drugs such as corticosteroids, azathioprine, and mycophenolate mofetil, and thymectomy, which is primarily indicated in patients with thymoma or thymic hyperplasia. However, this condition continues to pose significant challenges including an unpredictable and variable disease progression, differing response to individual therapies, and substantial longterm side effects associated with standard treatments(including an increased risk of infections, osteoporosis, and diabetes), underscoring the necessity for a more personalized approach to treatment. Furthermore, about fifteen percent of patients, called “refractory myasthenia gravis patients”, do not respond adequately to standard therapies. In this context, the introduction of molecular therapies has marked a significant advance in myasthenia gravis management. Advances in understanding myasthenia gravis pathogenesis, especially the role of pathogenic antibodies, have driven the development of these biological drugs, which offer more selective, rapid, and safer alternatives to traditional immunosuppressants. This review aims to provide a comprehensive overview of emerging therapeutic strategies targeting specific immune pathways in myasthenia gravis, with a particular focus on preclinical evidence, therapeutic rationale, and clinical translation of B-cell depletion therapies, neonatal Fc receptor inhibitors, and complement inhibitors. 展开更多
关键词 acetylcholine receptor(AChR) animal models B-cell depletion biological therapies COMPLEMENT IMMUNOTHERAPY muscle-specific kinase(Mu SK) neonatal Fc receptor
暂未订购
上一页 1 2 250 下一页 到第
使用帮助 返回顶部