Scandium-substituted Al_(2)Mo_(3)O_(12)ceramics corresponding to the general formula Al_(2-x)Sc_(x)Mo_(3)O_(12)(0≤x≤0.5)were fabricated by the co-precipitation reaction.Sc^(3+)is proved to successfully replace Al^(3...Scandium-substituted Al_(2)Mo_(3)O_(12)ceramics corresponding to the general formula Al_(2-x)Sc_(x)Mo_(3)O_(12)(0≤x≤0.5)were fabricated by the co-precipitation reaction.Sc^(3+)is proved to successfully replace Al^(3+)and reduces the average grain size of the Al_(2-x)Sc_(x)Mo_(3)O_(12)ceramics from 6µm to 1µm.Sc^(3+)substitution induces a crystal structure change from monoclinic to orthorhombic symmetry.展开更多
We present a novel electrochemical sensor for the detection of alfuzosin(AFZ),an alpha1-adrenoceptor(α_(1)-AR)antagonist using metal-organic framework(MOF)-derived zinc oxide/cobalt oxide(ZnO/Co_(3)O_(4))decorated on...We present a novel electrochemical sensor for the detection of alfuzosin(AFZ),an alpha1-adrenoceptor(α_(1)-AR)antagonist using metal-organic framework(MOF)-derived zinc oxide/cobalt oxide(ZnO/Co_(3)O_(4))decorated on graphene(Gr).The co-precipitation method was utilized to synthesize a binary metal oxide derived from the MOF,and then ultrasonication was employed to prepare the ZnO/Co_(3)O_(4)@Gr nanocomposite.The prepared ZnO/Co_(3)O_(4)@Gr nanocomposite was characterized by X-ray diffraction(XRD),X-ray photoelectron spectroscopy(XPS),attenuated total reflectance-infrared(ATR-IR)spectroscopy,field emission scanning electron microscopy(FE-SEM),and high-resolution transmission electron microscopy(HR-TEM).The nanocomposite was modified on a glassy carbon electrode(GCE)to construct an electrochemical AFZ sensor,which exhibited a linear range of 0.05-40μM and a low limit of detection(LOD)of 0.004μM.The sensor showed good selectivity,as well as excellent reproducibility and storage stability.We also conducted the real sample analysis of the modified electrode for the detection of AFZ in pharmaceutical tablets,human serum,and urine samples,which delivered adequate recoveries.The ZnO/Co_(3)O_(4)@Gr nanocomposite-based electrochemical sensor is a promising candidate for the efficient and accurate detection of AFZ,owing to its superior sensitivity,selectivity,reproducibility,and stability.展开更多
基金National Natural Science Foundation of China(No.51602280 and 51102207)Qing Lan Project of Jiangsu Province,Postgraduate Research&Practice Innovation Program of Jiangsu Province(SJCX18_0794).
文摘Scandium-substituted Al_(2)Mo_(3)O_(12)ceramics corresponding to the general formula Al_(2-x)Sc_(x)Mo_(3)O_(12)(0≤x≤0.5)were fabricated by the co-precipitation reaction.Sc^(3+)is proved to successfully replace Al^(3+)and reduces the average grain size of the Al_(2-x)Sc_(x)Mo_(3)O_(12)ceramics from 6µm to 1µm.Sc^(3+)substitution induces a crystal structure change from monoclinic to orthorhombic symmetry.
基金supported by the Basic Science Research Program through the National Research Foundation of Korea(NRF),with a grant funded by the Korea Government(MSIT)(No.NRF-2020R1A2C1014918)the Korea Basic Science Institute(National Research Facilities and Equipment Center)grant funded by the Ministry of Education(2022R1A6C101B794)the MOE(NRF-2021R1A6A1A03039503)+1 种基金This work was conducted with the support of the Korea Environment Industry&Technology Institute(KEITI)through its Ecological Imitation-based Environmental Pollution Management Technology Development Project and by the Korea Ministry of Environment(ME)(2019002800006)supported by the Soonchunhyang University Research Fund.
文摘We present a novel electrochemical sensor for the detection of alfuzosin(AFZ),an alpha1-adrenoceptor(α_(1)-AR)antagonist using metal-organic framework(MOF)-derived zinc oxide/cobalt oxide(ZnO/Co_(3)O_(4))decorated on graphene(Gr).The co-precipitation method was utilized to synthesize a binary metal oxide derived from the MOF,and then ultrasonication was employed to prepare the ZnO/Co_(3)O_(4)@Gr nanocomposite.The prepared ZnO/Co_(3)O_(4)@Gr nanocomposite was characterized by X-ray diffraction(XRD),X-ray photoelectron spectroscopy(XPS),attenuated total reflectance-infrared(ATR-IR)spectroscopy,field emission scanning electron microscopy(FE-SEM),and high-resolution transmission electron microscopy(HR-TEM).The nanocomposite was modified on a glassy carbon electrode(GCE)to construct an electrochemical AFZ sensor,which exhibited a linear range of 0.05-40μM and a low limit of detection(LOD)of 0.004μM.The sensor showed good selectivity,as well as excellent reproducibility and storage stability.We also conducted the real sample analysis of the modified electrode for the detection of AFZ in pharmaceutical tablets,human serum,and urine samples,which delivered adequate recoveries.The ZnO/Co_(3)O_(4)@Gr nanocomposite-based electrochemical sensor is a promising candidate for the efficient and accurate detection of AFZ,owing to its superior sensitivity,selectivity,reproducibility,and stability.
