By using climate data in national stations in Xiji County,Ningxia during 1981 and 2020,a regression analysis was carried out on weather data in crop growth season in three automatic weather stations in Hulu River Vall...By using climate data in national stations in Xiji County,Ningxia during 1981 and 2020,a regression analysis was carried out on weather data in crop growth season in three automatic weather stations in Hulu River Valley. The results showed that celery belts of Hulu River Valley was divided into two groups: early-maturing region of south Xinglong-Xiaohe where is warm and rainy,serotinous region of north Jiqiang-Xinying where is warm and cold and rainless. Four subregions: Xinlong,Xiaohe,Jiqiang,Xinying. Each sub-region was divided into five regions according to climate layer and observation in growth season: temperature accumulating planting period,low temperature seedling period,suitable temperature for external leaf growth stage,high-temperature for celery mulching-sanded plantation in different sowing periods, water and fertilizer,insect prevention,time to market sales.展开更多
Based on 10 years of statistics concerning economic development in Xi'an as the main part of Guanzhong- Tianshui Economic Zone, this article builds the main indicator system to reflect economic development. Using ...Based on 10 years of statistics concerning economic development in Xi'an as the main part of Guanzhong- Tianshui Economic Zone, this article builds the main indicator system to reflect economic development. Using two mathematical methods( principal component analysis and cluster analysis),we carry out comprehensive evaluation analysis of the main economic indicators,point out the distribution differences in the economic development level in this region,and make classification,in order to provide a scientific basis for the decision- making body to lay down the relevant economic development strategies in accordance with the economic development level and geographical location.展开更多
17 indices are selected,such as the growth rate of total regional output value,the proportion of tertiary industry in GDP,per capita financial expenditure,and soil erosion rate of Guizhou Province in 2009.According to...17 indices are selected,such as the growth rate of total regional output value,the proportion of tertiary industry in GDP,per capita financial expenditure,and soil erosion rate of Guizhou Province in 2009.According to the relevant indices data of statistical yearbook and governmental website,by using the method of factor analysis and the method of cluster analysis,we assess the competitiveness of county economy in 88 counties of Guizhou Province.The results show that the competitiveness of county economy in Guizhou Province is impacted by factors of location and economic foundation.In addition,the resources environment,economic structure,economic developmental speed and other factors also impact the competitiveness of county economy in Guizhou Province.Based on these,in the light of the developmental characteristics of different counties in conjunction with different developmental advantages in different regions,we should adopt different developmental strategies according to local conditions,which is significant to rapid,healthy and sustainable development of county economy in Guizhou Province.展开更多
Introduction:Data on inter-regional transmission clusters of Hepatitis C Virus(HCV)helps optimize targeted preventive strategies.This study aims to detect the national and international dimensions of HCV 1b transmissi...Introduction:Data on inter-regional transmission clusters of Hepatitis C Virus(HCV)helps optimize targeted preventive strategies.This study aims to detect the national and international dimensions of HCV 1b transmission clusters.Methods:Available published HCV 1b nonstructural protein 5B sequences sampled between 1989 and 2021 were collected,including 1,750 sequences from China and 482 comparable sequences from other countries.Network-based and tree-based approaches were introduced to detect transmission clusters and infer their relationships.Results:Three distinct transmission cluster patterns were identified across China:a large cluster with nationwide distribution,two medium clusters predominantly in the Central and Eastern China,and 103 small clusters scattered across 19 provincial-level administrative divisions.No genetic linkages were found between Chinese sequences and those from other countries.The medium clusters exhibited a similar expansion risk compared with the large cluster[adjusted odds ratio(aOR)=1.247,95%confidence interval(CI):0.862,1.804,P=0.241],but showed significantly lower inter-provincial transmission(aOR=0.255,95%CI:0.077,0.798,P=0.019).The small clusters demonstrated faster expansion[adjusted hazard ratio(aHR)=1.327,95%CI:1.050,1.676,P=0.018]and markedly reduced inter-provincial transmission(aOR=0.006,95%CI:0.002,0.014,P<0.001)compared to the large cluster.The Northeast China groups showed significantly higher interprovincial transmission risk compared to the Central China groups(aOR=11.461,95%CI:2.262,87.014,P=0.006).Conclusions:This study emphasizes the urgent need to establish a national molecular epidemiological surveillance network for detecting hidden transmission chains and monitoring the emergence of variants.展开更多
Background: Chronic ulcers are responsible for considerable morbidity and significantly contribute to the escalation in the cost of health care. Chronic leg ulcers (CLUs) are susceptible to microbial infections and se...Background: Chronic ulcers are responsible for considerable morbidity and significantly contribute to the escalation in the cost of health care. Chronic leg ulcers (CLUs) are susceptible to microbial infections and serious complications such as tissue necrosis and osteomyelitis, can result without the timely control of infections. Recent studies have also reported an increase in the association of fungal infections with chronic non-healing ulcers. Aim: To determine the prevalence of bacterial and fungal infections among patients reporting with chronic leg ulcers in participants without co-morbidities. Methods: A prospective cross-sectional study was conducted among patients with chronic leg ulcers at the National Reconstructive Plastic Surgery and Burns Centre, Korle-Bu Teaching Hospital (NRPS/BC-KBTH) and those who consented were enrolled. Characteristics of the wound as well as micro-organisms cultured from wound swabs were recorded. Results: A total of 50 participants were enrolled for the study with the mean (SD) age of 40.7 (10.7) years. Eighty percent of the participants presented with post traumatic leg ulcers with 80% being artisans and traders in the age group 31 - 50 years. There was no statistically significant association between sex and the organism cultured for post traumatic and cellulitis (p-value > 0.05). The prevalence of bacterial and fungal infection was 79.3% and 20.7% respectively. Pseudomonas species was the most isolated bacteria (61.5%) while Aspergillus niger was the most isolated fungi (41%). Conclusion: From this study, fungal infections should be included in managing chronic leg ulcers, especially among artisans, famers and gardeners even though there was a significantly higher burden of bacterial infections.展开更多
●AIM:To investigate the underlying mechanism of dry environment(autumn dryness)affecting the lacrimal glands in rats.●METHODS:Twenty Sprague-Dawley rats were randomly divided into two groups.The rats were fed in spe...●AIM:To investigate the underlying mechanism of dry environment(autumn dryness)affecting the lacrimal glands in rats.●METHODS:Twenty Sprague-Dawley rats were randomly divided into two groups.The rats were fed in specific pathogen free environment as the control group(n=10),and the rats fed in dry environment as the dryness group(n=10).After 24d,lacrimal glands were collected from the rats.The tissues morphology was observed by hematoxylineosin(HE)staining.Tandem mass tags(TMT)quantitative proteomics analysis technology was used to screen the differential expressed proteins of lacrimal glands between the two groups,then bioinformatics analysis was performed.Further,the immunohistochemical(IHC)method was used to verify the target proteins.●RESULTS:In dryness group,the lacrimal glands lobule atrophied,the glandular cavities enlarged,the sparse nuclear distribution and scattered inflammatory infiltration between the acinus were observed.The proteomics exhibited that a total of 195 up-regulated and 236 downregulated differential expressed proteins screened from the lacrimal glands of rats.It was indicated that the biological processes(BP)of differential expressed proteins mainly included cell processes and single BP.The cellular compositions of differential expressed proteins mainly located in cells,organelles.The molecular functions of differential expressed proteins mainly included binding,catalytic activity.Moreover,the Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis showed that the differential expressed proteins mainly involved lysosome,complement and coagulation cascade,and ribosome pathway.The IHC result verified that the up-regulated expression proteins of Protein S100A9(S100A9),Annexin A1(Anxa1),and Clusterin(Clu)in lacrimal glands of rats in dryness group were higher than control group.●CONCLUSION:The up-regulated expression proteins of S100A9,Anxa1,and Clu may be the potential mechanisms of dry eye symptoms caused by dry environment.This study provides clues of dry environments causing eye-related diseases for further studies.展开更多
基金Supported by"Celery Plantation Experiment"of Meteorological Science and Technology in 2011 in Ningxia Meteorological Bureau
文摘By using climate data in national stations in Xiji County,Ningxia during 1981 and 2020,a regression analysis was carried out on weather data in crop growth season in three automatic weather stations in Hulu River Valley. The results showed that celery belts of Hulu River Valley was divided into two groups: early-maturing region of south Xinglong-Xiaohe where is warm and rainy,serotinous region of north Jiqiang-Xinying where is warm and cold and rainless. Four subregions: Xinlong,Xiaohe,Jiqiang,Xinying. Each sub-region was divided into five regions according to climate layer and observation in growth season: temperature accumulating planting period,low temperature seedling period,suitable temperature for external leaf growth stage,high-temperature for celery mulching-sanded plantation in different sowing periods, water and fertilizer,insect prevention,time to market sales.
基金Shaanxi Natural Science Fundamental Research Foundation(2011JM1019)
文摘Based on 10 years of statistics concerning economic development in Xi'an as the main part of Guanzhong- Tianshui Economic Zone, this article builds the main indicator system to reflect economic development. Using two mathematical methods( principal component analysis and cluster analysis),we carry out comprehensive evaluation analysis of the main economic indicators,point out the distribution differences in the economic development level in this region,and make classification,in order to provide a scientific basis for the decision- making body to lay down the relevant economic development strategies in accordance with the economic development level and geographical location.
基金Supported by Soft Science United Fund of Technology Department of Guizhou Province([2010]2LKC2015)Special Program of Humanities and Social Sciences of Technology Department of Guizhou Province(09ZX119)
文摘17 indices are selected,such as the growth rate of total regional output value,the proportion of tertiary industry in GDP,per capita financial expenditure,and soil erosion rate of Guizhou Province in 2009.According to the relevant indices data of statistical yearbook and governmental website,by using the method of factor analysis and the method of cluster analysis,we assess the competitiveness of county economy in 88 counties of Guizhou Province.The results show that the competitiveness of county economy in Guizhou Province is impacted by factors of location and economic foundation.In addition,the resources environment,economic structure,economic developmental speed and other factors also impact the competitiveness of county economy in Guizhou Province.Based on these,in the light of the developmental characteristics of different counties in conjunction with different developmental advantages in different regions,we should adopt different developmental strategies according to local conditions,which is significant to rapid,healthy and sustainable development of county economy in Guizhou Province.
基金Supported by the National Natural Science Foundation of China(12071366)the project of the Disease Control and Prevention Administration of Guangxi Zhuang Autonomous Region(GXJKKJ24C002).
文摘Introduction:Data on inter-regional transmission clusters of Hepatitis C Virus(HCV)helps optimize targeted preventive strategies.This study aims to detect the national and international dimensions of HCV 1b transmission clusters.Methods:Available published HCV 1b nonstructural protein 5B sequences sampled between 1989 and 2021 were collected,including 1,750 sequences from China and 482 comparable sequences from other countries.Network-based and tree-based approaches were introduced to detect transmission clusters and infer their relationships.Results:Three distinct transmission cluster patterns were identified across China:a large cluster with nationwide distribution,two medium clusters predominantly in the Central and Eastern China,and 103 small clusters scattered across 19 provincial-level administrative divisions.No genetic linkages were found between Chinese sequences and those from other countries.The medium clusters exhibited a similar expansion risk compared with the large cluster[adjusted odds ratio(aOR)=1.247,95%confidence interval(CI):0.862,1.804,P=0.241],but showed significantly lower inter-provincial transmission(aOR=0.255,95%CI:0.077,0.798,P=0.019).The small clusters demonstrated faster expansion[adjusted hazard ratio(aHR)=1.327,95%CI:1.050,1.676,P=0.018]and markedly reduced inter-provincial transmission(aOR=0.006,95%CI:0.002,0.014,P<0.001)compared to the large cluster.The Northeast China groups showed significantly higher interprovincial transmission risk compared to the Central China groups(aOR=11.461,95%CI:2.262,87.014,P=0.006).Conclusions:This study emphasizes the urgent need to establish a national molecular epidemiological surveillance network for detecting hidden transmission chains and monitoring the emergence of variants.
文摘Background: Chronic ulcers are responsible for considerable morbidity and significantly contribute to the escalation in the cost of health care. Chronic leg ulcers (CLUs) are susceptible to microbial infections and serious complications such as tissue necrosis and osteomyelitis, can result without the timely control of infections. Recent studies have also reported an increase in the association of fungal infections with chronic non-healing ulcers. Aim: To determine the prevalence of bacterial and fungal infections among patients reporting with chronic leg ulcers in participants without co-morbidities. Methods: A prospective cross-sectional study was conducted among patients with chronic leg ulcers at the National Reconstructive Plastic Surgery and Burns Centre, Korle-Bu Teaching Hospital (NRPS/BC-KBTH) and those who consented were enrolled. Characteristics of the wound as well as micro-organisms cultured from wound swabs were recorded. Results: A total of 50 participants were enrolled for the study with the mean (SD) age of 40.7 (10.7) years. Eighty percent of the participants presented with post traumatic leg ulcers with 80% being artisans and traders in the age group 31 - 50 years. There was no statistically significant association between sex and the organism cultured for post traumatic and cellulitis (p-value > 0.05). The prevalence of bacterial and fungal infection was 79.3% and 20.7% respectively. Pseudomonas species was the most isolated bacteria (61.5%) while Aspergillus niger was the most isolated fungi (41%). Conclusion: From this study, fungal infections should be included in managing chronic leg ulcers, especially among artisans, famers and gardeners even though there was a significantly higher burden of bacterial infections.
基金Supported by Regional Science Foundation Project of the National Natural Science Foundation of China(No.82060827,No.82260891)The Key Discipline of Universities in the“14th Five-Year Plan”Autonomous Region-Traditional Chinese Medicine at Xinjiang Medical University.
文摘●AIM:To investigate the underlying mechanism of dry environment(autumn dryness)affecting the lacrimal glands in rats.●METHODS:Twenty Sprague-Dawley rats were randomly divided into two groups.The rats were fed in specific pathogen free environment as the control group(n=10),and the rats fed in dry environment as the dryness group(n=10).After 24d,lacrimal glands were collected from the rats.The tissues morphology was observed by hematoxylineosin(HE)staining.Tandem mass tags(TMT)quantitative proteomics analysis technology was used to screen the differential expressed proteins of lacrimal glands between the two groups,then bioinformatics analysis was performed.Further,the immunohistochemical(IHC)method was used to verify the target proteins.●RESULTS:In dryness group,the lacrimal glands lobule atrophied,the glandular cavities enlarged,the sparse nuclear distribution and scattered inflammatory infiltration between the acinus were observed.The proteomics exhibited that a total of 195 up-regulated and 236 downregulated differential expressed proteins screened from the lacrimal glands of rats.It was indicated that the biological processes(BP)of differential expressed proteins mainly included cell processes and single BP.The cellular compositions of differential expressed proteins mainly located in cells,organelles.The molecular functions of differential expressed proteins mainly included binding,catalytic activity.Moreover,the Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis showed that the differential expressed proteins mainly involved lysosome,complement and coagulation cascade,and ribosome pathway.The IHC result verified that the up-regulated expression proteins of Protein S100A9(S100A9),Annexin A1(Anxa1),and Clusterin(Clu)in lacrimal glands of rats in dryness group were higher than control group.●CONCLUSION:The up-regulated expression proteins of S100A9,Anxa1,and Clu may be the potential mechanisms of dry eye symptoms caused by dry environment.This study provides clues of dry environments causing eye-related diseases for further studies.
