Microneedle technology has undergone a paradigm shift from basic transdermal drug delivery to intelligent,closed-loop theranostic systems.Hydrogel materials have emerged as core carriers due to their excellent biocomp...Microneedle technology has undergone a paradigm shift from basic transdermal drug delivery to intelligent,closed-loop theranostic systems.Hydrogel materials have emerged as core carriers due to their excellent biocompatibility,efficient drug loading capacity,and improved patient compliance.Moreover,critical bottlenecks in hydrogel microneedles,including poor mechanical strength,burst release of drugs,and delayed response to treatment,can be addressed via cross-scale integration of nanomaterials.This review systematically outlines several multiscale engineering strategies to overcome these limitations.The construction of nanotopological networks coupled with dynamic crosslinking modulation synergistically enhances the mechanical properties,stability of drug loading,and conductivity of hydrogel microneedles.Furthermore,responsive nanocarriers equipped with biosensors help establish a closed-loop linkage between monitoring and therapeutic functions.We highlight their synergistic theranostic advantages in scenarios such as wound regulation and tumor-immune microenvironments,while revealing the role in integrating flexible electronics with wearable systems in intelligent medicine.We also summarize the research advances on the biosafety and scalable manufacturing processes of nanocomposite hydrogel m icroneedles(NHMNs),providing examples of clinical translation to elucidate the path from fundamental research to industrial implementation.As a convergence of nanotechnology,biomaterials,and flexible electronics,NHMNs provide new standards for transdermal theranostics as well as a roadmap for iterative advancement of intelligent theranostic devices in personalized medicine.Their cross-scale collaborative design,which spans from the properties of materials to the functional integration of macroscopic devices,can facilitate potential breakthroughs in next-generation closed-loop theranostic systems.展开更多
Against the backdrop of continuous social development and growing public health demands,the efficiency and scientific nature of the emergency care system are of paramount importance.This paper focuses on researching t...Against the backdrop of continuous social development and growing public health demands,the efficiency and scientific nature of the emergency care system are of paramount importance.This paper focuses on researching the construction of an emergency care system based on the concept of“linkage”,delving into its theoretical foundations,exploring innovative construction models,and analyzing practical cases.The study indicates that an emergency care system under the“linkage”concept can effectively integrate resources and enhance efficiency,providing new insights for improving the construction of the emergency care system.It aims to promote the development of the emergency care system towards a more scientific,efficient,and collaborative direction.展开更多
The concept of Damage Control Surgery(DCS)emphasizes prioritizing hemorrhage control,preventing hypothermia,correcting coagulopathy,and acidosis in trauma treatment.The application of the DCS concept in trauma treatme...The concept of Damage Control Surgery(DCS)emphasizes prioritizing hemorrhage control,preventing hypothermia,correcting coagulopathy,and acidosis in trauma treatment.The application of the DCS concept in trauma treatment at grassroots hospitals faces numerous challenges such as limited resources,high technical difficulty,and insufficient multidisciplinary collaboration.Therefore,DCS strategies need to be adapted to simplified processes to create conditions for subsequent treatment.This paper retrieves relevant literature to discuss the proposal,promotion,and application of the DCS concept,aiming to provide evidence-based basis for optimizing trauma treatment outcomes at grassroots hospitals.展开更多
Objectives This study aimed to explore and clarify the concept of reflective supervision as a professional self-care strategy to create a positive Intensive Care Unit(ICU)practice environment.Methods Walker and Avant...Objectives This study aimed to explore and clarify the concept of reflective supervision as a professional self-care strategy to create a positive Intensive Care Unit(ICU)practice environment.Methods Walker and Avant’s eight-step concept analysis approach was utilized to identify and define the attributes,antecedents,and consequences of reflective supervision in the ICU.An extensive literature search was conducted across various databases,including Google Scholar,CINAHL,PubMed.Articles published from 2005 to 2025 were identified.We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA)2020 statement to indicate the included articles and extract related data based on relevance.Results Forty articles were included in the analysis.The identified attributes included the supervisor-supervisee relationship,effective communication,teamwork,collaborations,reflection,competencies,feedback,continuous support,and autonomous choice.The identified antecedents included participation,supportive supervision,flexibility,open-door policy,training,and motivation.Consequences impacting the success of reflective supervision were identified as promotion of resiliency,autonomy,work-life balance,self-awareness,increased self-esteem,professional development,critical thinking,increased job satisfaction,and enhanced commitment.Conclusions Reflective supervision is a complex professional self-care strategy that enhances ICU practice,by promoting nurses’well-being,self-awareness,therapeutic skills,and professional development.展开更多
Processes supported by process-aware information systems are subject to continuous and often subtle changes due to evolving operational,organizational,or regulatory factors.These changes,referred to as incremental con...Processes supported by process-aware information systems are subject to continuous and often subtle changes due to evolving operational,organizational,or regulatory factors.These changes,referred to as incremental concept drift,gradually alter the behavior or structure of processes,making their detection and localization a challenging task.Traditional process mining techniques frequently assume process stationarity and are limited in their ability to detect such drift,particularly from a control-flow perspective.The objective of this research is to develop an interpretable and robust framework capable of detecting and localizing incremental concept drift in event logs,with a specific emphasis on the structural evolution of control-flow semantics in processes.We propose DriftXMiner,a control-flow-aware hybrid framework that combines statistical,machine learning,and process model analysis techniques.The approach comprises three key components:(1)Cumulative Drift Scanner that tracks directional statistical deviations to detect early drift signals;(2)a Temporal Clustering and Drift-Aware Forest Ensemble(DAFE)to capture distributional and classification-level changes in process behavior;and(3)Petri net-based process model reconstruction,which enables the precise localization of structural drift using transition deviation metrics and replay fitness scores.Experimental validation on the BPI Challenge 2017 event log demonstrates that DriftXMiner effectively identifies and localizes gradual and incremental process drift over time.The framework achieves a detection accuracy of 92.5%,a localization precision of 90.3%,and an F1-score of 0.91,outperforming competitive baselines such as CUSUM+Histograms and ADWIN+Alpha Miner.Visual analyses further confirm that identified drift points align with transitions in control-flow models and behavioral cluster structures.DriftXMiner offers a novel and interpretable solution for incremental concept drift detection and localization in dynamic,process-aware systems.By integrating statistical signal accumulation,temporal behavior profiling,and structural process mining,the framework enables finegrained drift explanation and supports adaptive process intelligence in evolving environments.Its modular architecture supports extension to streaming data and real-time monitoring contexts.展开更多
Many machine learning-based Android malware detection often suffers from concept drift,where models trained on historical data fail to generalize to evolving threats.This paper proposes SCAN(Structural Clustering with...Many machine learning-based Android malware detection often suffers from concept drift,where models trained on historical data fail to generalize to evolving threats.This paper proposes SCAN(Structural Clustering with Adaptive thresholds for iNtelligent Android malware detection),a hybrid intelligent framework designed to mitigate concept drift without retraining.SCAN integrates Gaussian Mixture Models(GMMs)-based clustering with cluster-wise adaptive thresholding and supervised classifiers tailored to each cluster.A key challenge in clusteringbased malware detection is cluster-wise class imbalance,where clusters contain disproportionate distributions of benign and malicious samples.SCAN addresses this issue through adaptive thresholding,which dynamically adjusts the decision boundary of each cluster according to its malicious-to-benign ratio.In the final training stage,four supervised learning algorithms—Random Forest(RF),Support Vector Machine(SVM),k-NN,and XGBoost—are applied within the GMM-defined clusters.We train SCAN on Android applications collected from 2014-2017 and test it with applications from 2018-2023.Experimental results demonstrate that SCAN combined with RF consistently achieves superior performance,with both average accuracy and average F1-score exceeding 91%.These findings confirm SCAN’s robustness to concept drift and highlight its potential as a sustainable and intelligent solution for long-term Android malware detection in the real world.展开更多
This paper provides an adaptive closed-loop strategy for suppressing the pathological oscillations of the basal ganglia based on a variable universe fuzzy algorithm.The pathological basal ganglia oscillations in the t...This paper provides an adaptive closed-loop strategy for suppressing the pathological oscillations of the basal ganglia based on a variable universe fuzzy algorithm.The pathological basal ganglia oscillations in the theta(4-9 Hz)and beta(12-35 Hz)frequency bands have been demonstrated to be associated with the tremor and rigidity/bradykinesia symptoms in Parkinson’s disease(PD).Although the clinical application of open-loop deep brain stimulation(DBS)is effective,the stimulation waveform with the fixed parameters cannot be self-adjusted as the disease progresses,and thus the stimulation effects go poor.To deal with this difficult problem,a variable universe fuzzy closed-loop strategy is proposed to modulate different PD states.We establish a cortico-basal ganglia-thalamocortical network model to simulate pathological oscillations and test the control effect.The results suggest that the proposed closed-loop control strategy can accommodate the variation of brain states and symptoms,which may become an alternative method to administrate the symptoms in PD.展开更多
Since the reform and opening up,the development approach targeting urban economic growth has led to a sharp increase in the proportion of impervious hardened surfaces in cities and significant waste of natural resourc...Since the reform and opening up,the development approach targeting urban economic growth has led to a sharp increase in the proportion of impervious hardened surfaces in cities and significant waste of natural resources.The urgent need for water ecological civilization construction is of great significance to the continuation of human civilization in the long run.This paper focuses on the urban waterfront landscape design of the Chongqing Institute of Engineering section of the Huaxi River in Banan District,emphasizing the concept of“symbiosis”.Using site cultural symbols as a medium to connect the campus and the city on both sides of the river,returning the riverbank to the people,restoring the ecological space of the riverfront,enriching the landscape belt,promoting the protection of bird and fish habitats,and stimulating the vitality of the riverbank space;it aims to pave the way for ecological restoration,functional expansion,landscape renewal,and riverfront space activation at the study site.展开更多
Objective:To clarify the concept of in-home respite care in dementia care and identify changes in the service content over time to help providers and users better understand this sustainable service.Method:A literatur...Objective:To clarify the concept of in-home respite care in dementia care and identify changes in the service content over time to help providers and users better understand this sustainable service.Method:A literature search was conducted through Chinese databases China National Knowledge Infrastructure(CNKI),Wanfang,VIP,and SinoMed,as well as English databases PubMed,the Cochrane Library,Web of Sciences,and Embase.Articles published from January 1980 to December 2024 were identified.Rogers’conceptual analysis of evolution was used for this concept analysis,including six steps:identifying the concept and its context,selecting appropriate databases,determining relevant literature,identifying the concept’s attributes,antecedents,and consequences,choosing a concept exemplar if appropriate,and defininghypotheses and implications for further concept development.Results:Thirty-one articles were included.This conceptual analysis revealed the evolution of in-home respite care service content over time and summarized three key attributes.The antecedents included factors related to people with dementia,family caregivers,and the social environment(aging society,government support).The consequences of in-home respite services include delayed institutional placement and reduced security risk events for people with dementia.For family caregivers,consequences include reduced caregiving stress,improved quality of life,and perceived benefitsfrom rest periods.Conclusion:In-home respite care can be interpreted as family-centered home care that provides temporary relief from family caregivers’responsibilities in caring for people with dementia to reduce caregiver burden.The trend of service specialization and attention on dementia families’needs in service provision are future research focus.展开更多
This study aims to clarify the conceptual characteristics of artifact utilization in nursing practice instruction. Five selected articles were analyzed using the concept analysis method by Walker and Avant. The attrib...This study aims to clarify the conceptual characteristics of artifact utilization in nursing practice instruction. Five selected articles were analyzed using the concept analysis method by Walker and Avant. The attributes, antecedents, and consequences of the concept were extracted from the target literature. The analysis revealed two attributes (“connecting people to people” and “connecting people to objects”);two antecedents (“recognition of artifacts” and “selection of artifacts”);and two consequences (“designing a fulfilling learning environment” and “improving the quality of education”). The concept was defined as “promoting the utilization of artifacts by recognizing and selecting them, connecting people to people and people to objects, designing a fulfilling learning environment, and improving the quality of education”.展开更多
The cost and strict input format requirements of GraphRAG make it less efficient for processing large documents. This paper proposes an alternative approach for constructing a knowledge graph (KG) from a PDF document ...The cost and strict input format requirements of GraphRAG make it less efficient for processing large documents. This paper proposes an alternative approach for constructing a knowledge graph (KG) from a PDF document with a focus on simplicity and cost-effectiveness. The process involves splitting the document into chunks, extracting concepts within each chunk using a large language model (LLM), and building relationships based on the proximity of concepts in the same chunk. Unlike traditional named entity recognition (NER), which identifies entities like “Shanghai”, the proposed method identifies concepts, such as “Convenient transportation in Shanghai” which is found to be more meaningful for KG construction. Each edge in the KG represents a relationship between concepts occurring in the same text chunk. The process is computationally inexpensive, leveraging locally set up tools like Mistral 7B openorca instruct and Ollama for model inference, ensuring the entire graph generation process is cost-free. A method of assigning weights to relationships, grouping similar pairs, and summarizing multiple relationships into a single edge with associated weight and relation details is introduced. Additionally, node degrees and communities are calculated for node sizing and coloring. This approach offers a scalable, cost-effective solution for generating meaningful knowledge graphs from large documents, achieving results comparable to GraphRAG while maintaining accessibility for personal machines.展开更多
Prosthetic devices designed to assist individuals with damaged or missing body parts have made significant strides,particularly with advancements in machine intelligence and bioengineering.Initially focused on movemen...Prosthetic devices designed to assist individuals with damaged or missing body parts have made significant strides,particularly with advancements in machine intelligence and bioengineering.Initially focused on movement assistance,the field has shifted towards developing prosthetics that function as seamless extensions of the human body.During this progress,a key challenge remains the reduction of interface artifacts between prosthetic components and biological tissues.Soft electronics offer a promising solution due to their structural flexibility and enhanced tissue adaptability.However,achieving full integration of prosthetics with the human body requires both artificial perception and efficient transmission of physical signals.In this context,synaptic devices have garnered attention as next-generation neuromorphic computing elements because of their low power consumption,ability to enable hardware-based learning,and high compatibility with sensing units.These devices have the potential to create artificial pathways for sensory recognition and motor responses,forming a“sensory-neuromorphic system”that emulates synaptic junctions in biological neurons,thereby connecting with impaired biological tissues.Here,we discuss recent developments in prosthetic components and neuromorphic applications with a focus on sensory perception and sensorimotor actuation.Initially,we explore a prosthetic system with advanced sensory units,mechanical softness,and artificial intelligence,followed by the hardware implementation of memory devices that combine calculation and learning functions.We then highlight the importance and mechanisms of soft-form synaptic devices that are compatible with sensing units.Furthermore,we review an artificial sensory-neuromorphic perception system that replicates various biological senses and facilitates sensorimotor loops from sensory receptors,the spinal cord,and motor neurons.Finally,we propose insights into the future of closed-loop neuroprosthetics through the technical integration of soft electronics,including bio-integrated sensors and synaptic devices,into prosthetic systems.展开更多
Rotary steering systems(RSSs)have been increasingly used to develop horizontal wells.A static push-the-bit RSS uses three hydraulic modules with varying degrees of expansion and contraction to achieve changes in the p...Rotary steering systems(RSSs)have been increasingly used to develop horizontal wells.A static push-the-bit RSS uses three hydraulic modules with varying degrees of expansion and contraction to achieve changes in the pushing force acting on the wellbore in different sizes and directions within a circular range,ultimately allowing the wellbore trajectory to be drilled in a predetermined direction.By analyzing its mathematical principles and the actual characteristics of the instrument,a vector force closed-loop control method,including steering and holding modes,was designed.The adjustment criteria for the three hydraulic modules are determined to achieve rapid adjustment of the vector force.The theoretical feasibility of the developed method was verified by comparing its results with the on-site application data of an imported rotary guidance system.展开更多
Bariatric and metabolic surgeries have gained extensive popularity and trust due to their documented efficacy and safety in managing not only obesity but also associated comorbidities such as diabetes mellitus, hypert...Bariatric and metabolic surgeries have gained extensive popularity and trust due to their documented efficacy and safety in managing not only obesity but also associated comorbidities such as diabetes mellitus, hypertension, dyslipidemia, sleep apnea, and joint pain. Traditionally, bariatric surgeries have been categorized into hypoabsorptive, restrictive, or hybrid approaches. However, these classifications inadequately reflect the complex anatomical and physiological alterations associated with modern surgical methodologies. This paper explores the evolution of metabolic surgeries, emphasizing the integration of physiological concepts into classic procedures to provide more tailored and effective treatment options for obesity and its comorbidities. Finally, the proposal for a new classification based on current metabolic concepts will facilitate communication among patients, doctors, and healthcare professionals. Additionally, it will enable a more didactic and standardized approach to data collection for conducting studies and publications.展开更多
Objectives:This study aimed to establish the concept of overcoming exhaustion,providing a reference basis for nursing management and conducting related nursing research.Methods:Liehr and Smith’s three-phase,nine-step...Objectives:This study aimed to establish the concept of overcoming exhaustion,providing a reference basis for nursing management and conducting related nursing research.Methods:Liehr and Smith’s three-phase,nine-step concept-building process was used to create the concept of overcoming exhaustion.The nine steps were as follows:1)write a practice story;2)name the emerging concept;3)select a theoretical lens;4)link concept to literature;5)gather a concept story;6)identify final core qualities;7)formulate concept definition;8)create a concept model;and 9)specify the concept building synthesis.Results:The concept of overcoming exhaustion was identified based on the elements of a practice story,the life experiences of nurses who struggle with the demands of caring for their patients,their families,and themselves.The theory of self-transcendence was then recognized as the theoretical lens from which to ground the concept.The core qualities,despair and moments of calmness,were derived from the literature and confirmed through a concept story.A definition of the concept integrating the core qualities was formed:overcoming exhaustion involves realizing moments of calmness amidst despair.A model was created to demonstrate the relationship between core qualities,despair,and moments of calmness.Conclusions:The concept of overcoming exhaustion was developed and,through the concept-building process,was defined as realizing moments of calmness amidst despair.By identifying the complexities of overcoming exhaustion,this work lays the foundation for a future research program to develop understanding and interventions that support nurse well-being in the context of ongoing personal and professional demands.展开更多
This paper mainly discusses the innovative teaching mode of translation for English Majors under the guidance of OBE education philosophy.Firstly,by analyzing the current situation of translation teaching for English ...This paper mainly discusses the innovative teaching mode of translation for English Majors under the guidance of OBE education philosophy.Firstly,by analyzing the current situation of translation teaching for English majors,this paper points out the main problems,and combined with the OBE education concept,through optimizing the top-level design,updating the teaching content,improving the teaching methods,and scientifically using the evaluation methods,constructs a student-centered and outcome-oriented teaching mode.It is hoped that this study can improve students’translation ability and comprehensive quality,and provide a useful reference for the reform of translation teaching for English majors.展开更多
By analyzing the structure and academic characteristics of early Western Han medical texts such as Prescriptions for Fifty-Two Diseases(Wu Shi Er Bing Fang)and Prescriptions for Health Preservation(Yang Sheng Fang),an...By analyzing the structure and academic characteristics of early Western Han medical texts such as Prescriptions for Fifty-Two Diseases(Wu Shi Er Bing Fang)and Prescriptions for Health Preservation(Yang Sheng Fang),and considering the development of philosophical thinking during the pre-Qin and Han periods,this study summarizes how Zhongjing Zhang’s Treatise on Cold Damage and Miscellaneous Diseases(Shang Han Za Bing Lun)inherited pre-Qin and Han philosophical thought while further integrating Daoist“natural law”cosmology,Confucian“benevolence”social ethics,and the“isomorphic unity of heaven and humanity”medical theory in Yellow Emperor’s Inner Classic(Huang Di Nei Jing).It proposes health preservation concepts encompassing heaven-human,body-spirit,and benevolence perspectives,along with dietary hygiene,representing the medical embodiment of pre-Han“virtue cultivation”and“body nurturing”life philosophies that profoundly influenced subsequent traditional Chinese medicine health preservation theory and practice.展开更多
Conventional open-loop deep brain stimulation(DBS)systems with fixed parameters fail to accommodate interindividual pathological differences in Parkinson's disease(PD)management while potentially inducing adverse ...Conventional open-loop deep brain stimulation(DBS)systems with fixed parameters fail to accommodate interindividual pathological differences in Parkinson's disease(PD)management while potentially inducing adverse effects and causing excessive energy consumption.In this paper,we present an adaptive closed-loop framework integrating a Yogi-optimized proportional–integral–derivative neural network(Yogi-PIDNN)controller.The Yogi-augmented gradient adaptation mechanism accelerates the convergence of general PIDNN controllers in high-dimensional nonlinear control systems while reducing control energy usage.In addition,a system identification method establishes input–output dynamics for pre-training stimulation waveforms,bypassing real-time parameter-tuning constraints and thereby enhancing closed-loop adaptability.Finally,a theoretical analysis based on Lyapunov stability criteria establishes a sufficient condition for closed-loop stability within the identified model.Computational validations demonstrate that our approach restores thalamic relay reliability while reducing energy consumption by(81.0±0.7)%across multi-frequency tests.This study advances adaptive neuromodulation by synergizing data-driven pre-training with stability-guaranteed real-time control,offering a novel framework for energy-efficient and personalized Parkinson's therapy.展开更多
To define the concept of humanistic quality of nurses by Rodgers’evolutionary conceptual analysis.Based on Rodgers’s evolutionary concept analysis method as the theoretical basis to analyze the concept of humanistic...To define the concept of humanistic quality of nurses by Rodgers’evolutionary conceptual analysis.Based on Rodgers’s evolutionary concept analysis method as the theoretical basis to analyze the concept of humanistic literacy of nurses,the databases of CNKI,Wanfang,VIP,PubMed,Web of Science,and Science Direct were searched systematically from October 31st,2024.According to the inclusion and exclusion criteria,43 literatures were selected,including 34 Chinese literatures and 9 English literatures.Nurses’humanistic quality involved five conceptual attributes,including ethics,legal knowledge,traditional culture,interpersonal interaction,and aesthetic accomplishment.Antecedent variables include education environment,growth environment,hospital environment,and professional identity,and the consequences are divided into positive and negative aspects.Among them,positive consequences include harmonious nurse-patient relationships,efficient communication and cooperation,and improved nursing quality,while negative consequences include poor hospital operation,nurse-patient disputes,and reduced work quality.This paper defines and analyzes the humanistic qualities of nurses through the conceptual analysis of Rogers’theory of evolution,and the humanistic qualities of nurses refer to the comprehensive qualities of nurses based on ethics,legal knowledge,traditional culture,interpersonal interactions,and aesthetics in their professional practice,which will serve as a reference for future research in related fields.展开更多
基金supported by the National Key R esearch and Development Program of China(No.2023YFF0724300)the National Natural Science Foundation of China(No.32171373)+1 种基金the Fundamental Research Funds for the Central Universities(No.YG2025QNB08)the Natural Science Foundation of Shanghai(No.23ZR1414500).
文摘Microneedle technology has undergone a paradigm shift from basic transdermal drug delivery to intelligent,closed-loop theranostic systems.Hydrogel materials have emerged as core carriers due to their excellent biocompatibility,efficient drug loading capacity,and improved patient compliance.Moreover,critical bottlenecks in hydrogel microneedles,including poor mechanical strength,burst release of drugs,and delayed response to treatment,can be addressed via cross-scale integration of nanomaterials.This review systematically outlines several multiscale engineering strategies to overcome these limitations.The construction of nanotopological networks coupled with dynamic crosslinking modulation synergistically enhances the mechanical properties,stability of drug loading,and conductivity of hydrogel microneedles.Furthermore,responsive nanocarriers equipped with biosensors help establish a closed-loop linkage between monitoring and therapeutic functions.We highlight their synergistic theranostic advantages in scenarios such as wound regulation and tumor-immune microenvironments,while revealing the role in integrating flexible electronics with wearable systems in intelligent medicine.We also summarize the research advances on the biosafety and scalable manufacturing processes of nanocomposite hydrogel m icroneedles(NHMNs),providing examples of clinical translation to elucidate the path from fundamental research to industrial implementation.As a convergence of nanotechnology,biomaterials,and flexible electronics,NHMNs provide new standards for transdermal theranostics as well as a roadmap for iterative advancement of intelligent theranostic devices in personalized medicine.Their cross-scale collaborative design,which spans from the properties of materials to the functional integration of macroscopic devices,can facilitate potential breakthroughs in next-generation closed-loop theranostic systems.
文摘Against the backdrop of continuous social development and growing public health demands,the efficiency and scientific nature of the emergency care system are of paramount importance.This paper focuses on researching the construction of an emergency care system based on the concept of“linkage”,delving into its theoretical foundations,exploring innovative construction models,and analyzing practical cases.The study indicates that an emergency care system under the“linkage”concept can effectively integrate resources and enhance efficiency,providing new insights for improving the construction of the emergency care system.It aims to promote the development of the emergency care system towards a more scientific,efficient,and collaborative direction.
文摘The concept of Damage Control Surgery(DCS)emphasizes prioritizing hemorrhage control,preventing hypothermia,correcting coagulopathy,and acidosis in trauma treatment.The application of the DCS concept in trauma treatment at grassroots hospitals faces numerous challenges such as limited resources,high technical difficulty,and insufficient multidisciplinary collaboration.Therefore,DCS strategies need to be adapted to simplified processes to create conditions for subsequent treatment.This paper retrieves relevant literature to discuss the proposal,promotion,and application of the DCS concept,aiming to provide evidence-based basis for optimizing trauma treatment outcomes at grassroots hospitals.
文摘Objectives This study aimed to explore and clarify the concept of reflective supervision as a professional self-care strategy to create a positive Intensive Care Unit(ICU)practice environment.Methods Walker and Avant’s eight-step concept analysis approach was utilized to identify and define the attributes,antecedents,and consequences of reflective supervision in the ICU.An extensive literature search was conducted across various databases,including Google Scholar,CINAHL,PubMed.Articles published from 2005 to 2025 were identified.We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA)2020 statement to indicate the included articles and extract related data based on relevance.Results Forty articles were included in the analysis.The identified attributes included the supervisor-supervisee relationship,effective communication,teamwork,collaborations,reflection,competencies,feedback,continuous support,and autonomous choice.The identified antecedents included participation,supportive supervision,flexibility,open-door policy,training,and motivation.Consequences impacting the success of reflective supervision were identified as promotion of resiliency,autonomy,work-life balance,self-awareness,increased self-esteem,professional development,critical thinking,increased job satisfaction,and enhanced commitment.Conclusions Reflective supervision is a complex professional self-care strategy that enhances ICU practice,by promoting nurses’well-being,self-awareness,therapeutic skills,and professional development.
文摘Processes supported by process-aware information systems are subject to continuous and often subtle changes due to evolving operational,organizational,or regulatory factors.These changes,referred to as incremental concept drift,gradually alter the behavior or structure of processes,making their detection and localization a challenging task.Traditional process mining techniques frequently assume process stationarity and are limited in their ability to detect such drift,particularly from a control-flow perspective.The objective of this research is to develop an interpretable and robust framework capable of detecting and localizing incremental concept drift in event logs,with a specific emphasis on the structural evolution of control-flow semantics in processes.We propose DriftXMiner,a control-flow-aware hybrid framework that combines statistical,machine learning,and process model analysis techniques.The approach comprises three key components:(1)Cumulative Drift Scanner that tracks directional statistical deviations to detect early drift signals;(2)a Temporal Clustering and Drift-Aware Forest Ensemble(DAFE)to capture distributional and classification-level changes in process behavior;and(3)Petri net-based process model reconstruction,which enables the precise localization of structural drift using transition deviation metrics and replay fitness scores.Experimental validation on the BPI Challenge 2017 event log demonstrates that DriftXMiner effectively identifies and localizes gradual and incremental process drift over time.The framework achieves a detection accuracy of 92.5%,a localization precision of 90.3%,and an F1-score of 0.91,outperforming competitive baselines such as CUSUM+Histograms and ADWIN+Alpha Miner.Visual analyses further confirm that identified drift points align with transitions in control-flow models and behavioral cluster structures.DriftXMiner offers a novel and interpretable solution for incremental concept drift detection and localization in dynamic,process-aware systems.By integrating statistical signal accumulation,temporal behavior profiling,and structural process mining,the framework enables finegrained drift explanation and supports adaptive process intelligence in evolving environments.Its modular architecture supports extension to streaming data and real-time monitoring contexts.
基金supported in part by Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Science and ICT(No.2021R1A2C2012574)in part by the IITP(Institute of Information&Communications Technology Planning&Evaluation)-ITRC(Information Technology Research Center)grant funded by the Korea government(Ministry of Science and ICT)(IITP-2025-RS-2023-00259967).
文摘Many machine learning-based Android malware detection often suffers from concept drift,where models trained on historical data fail to generalize to evolving threats.This paper proposes SCAN(Structural Clustering with Adaptive thresholds for iNtelligent Android malware detection),a hybrid intelligent framework designed to mitigate concept drift without retraining.SCAN integrates Gaussian Mixture Models(GMMs)-based clustering with cluster-wise adaptive thresholding and supervised classifiers tailored to each cluster.A key challenge in clusteringbased malware detection is cluster-wise class imbalance,where clusters contain disproportionate distributions of benign and malicious samples.SCAN addresses this issue through adaptive thresholding,which dynamically adjusts the decision boundary of each cluster according to its malicious-to-benign ratio.In the final training stage,four supervised learning algorithms—Random Forest(RF),Support Vector Machine(SVM),k-NN,and XGBoost—are applied within the GMM-defined clusters.We train SCAN on Android applications collected from 2014-2017 and test it with applications from 2018-2023.Experimental results demonstrate that SCAN combined with RF consistently achieves superior performance,with both average accuracy and average F1-score exceeding 91%.These findings confirm SCAN’s robustness to concept drift and highlight its potential as a sustainable and intelligent solution for long-term Android malware detection in the real world.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.62173241 and 62171312)the Natural Science Foundation of Tianjin,China(Grant Nos.20JCQNJC01160 and 19JCZDJC36500)the financial support provided by Opening Foundation of Key Laboratory of Opto-technology and Intelligent Control(Lanzhou Jiaotong University),Ministry of Education,China(Grant No.KFKT2020-01)
文摘This paper provides an adaptive closed-loop strategy for suppressing the pathological oscillations of the basal ganglia based on a variable universe fuzzy algorithm.The pathological basal ganglia oscillations in the theta(4-9 Hz)and beta(12-35 Hz)frequency bands have been demonstrated to be associated with the tremor and rigidity/bradykinesia symptoms in Parkinson’s disease(PD).Although the clinical application of open-loop deep brain stimulation(DBS)is effective,the stimulation waveform with the fixed parameters cannot be self-adjusted as the disease progresses,and thus the stimulation effects go poor.To deal with this difficult problem,a variable universe fuzzy closed-loop strategy is proposed to modulate different PD states.We establish a cortico-basal ganglia-thalamocortical network model to simulate pathological oscillations and test the control effect.The results suggest that the proposed closed-loop control strategy can accommodate the variation of brain states and symptoms,which may become an alternative method to administrate the symptoms in PD.
基金Chongqing Institute of Engineering School-level Project:Research on Urban Waterfront Landscape Design Based on the Concept of River Ecological Restoration-Taking the Section of Chongqing Institute of Engineering on Huaxi River as an Example(Project No.:2022xskz02)。
文摘Since the reform and opening up,the development approach targeting urban economic growth has led to a sharp increase in the proportion of impervious hardened surfaces in cities and significant waste of natural resources.The urgent need for water ecological civilization construction is of great significance to the continuation of human civilization in the long run.This paper focuses on the urban waterfront landscape design of the Chongqing Institute of Engineering section of the Huaxi River in Banan District,emphasizing the concept of“symbiosis”.Using site cultural symbols as a medium to connect the campus and the city on both sides of the river,returning the riverbank to the people,restoring the ecological space of the riverfront,enriching the landscape belt,promoting the protection of bird and fish habitats,and stimulating the vitality of the riverbank space;it aims to pave the way for ecological restoration,functional expansion,landscape renewal,and riverfront space activation at the study site.
基金supported by the Fundamental Research Funds for the Central Universities(lzujbky-2022-it36)。
文摘Objective:To clarify the concept of in-home respite care in dementia care and identify changes in the service content over time to help providers and users better understand this sustainable service.Method:A literature search was conducted through Chinese databases China National Knowledge Infrastructure(CNKI),Wanfang,VIP,and SinoMed,as well as English databases PubMed,the Cochrane Library,Web of Sciences,and Embase.Articles published from January 1980 to December 2024 were identified.Rogers’conceptual analysis of evolution was used for this concept analysis,including six steps:identifying the concept and its context,selecting appropriate databases,determining relevant literature,identifying the concept’s attributes,antecedents,and consequences,choosing a concept exemplar if appropriate,and defininghypotheses and implications for further concept development.Results:Thirty-one articles were included.This conceptual analysis revealed the evolution of in-home respite care service content over time and summarized three key attributes.The antecedents included factors related to people with dementia,family caregivers,and the social environment(aging society,government support).The consequences of in-home respite services include delayed institutional placement and reduced security risk events for people with dementia.For family caregivers,consequences include reduced caregiving stress,improved quality of life,and perceived benefitsfrom rest periods.Conclusion:In-home respite care can be interpreted as family-centered home care that provides temporary relief from family caregivers’responsibilities in caring for people with dementia to reduce caregiver burden.The trend of service specialization and attention on dementia families’needs in service provision are future research focus.
文摘This study aims to clarify the conceptual characteristics of artifact utilization in nursing practice instruction. Five selected articles were analyzed using the concept analysis method by Walker and Avant. The attributes, antecedents, and consequences of the concept were extracted from the target literature. The analysis revealed two attributes (“connecting people to people” and “connecting people to objects”);two antecedents (“recognition of artifacts” and “selection of artifacts”);and two consequences (“designing a fulfilling learning environment” and “improving the quality of education”). The concept was defined as “promoting the utilization of artifacts by recognizing and selecting them, connecting people to people and people to objects, designing a fulfilling learning environment, and improving the quality of education”.
文摘The cost and strict input format requirements of GraphRAG make it less efficient for processing large documents. This paper proposes an alternative approach for constructing a knowledge graph (KG) from a PDF document with a focus on simplicity and cost-effectiveness. The process involves splitting the document into chunks, extracting concepts within each chunk using a large language model (LLM), and building relationships based on the proximity of concepts in the same chunk. Unlike traditional named entity recognition (NER), which identifies entities like “Shanghai”, the proposed method identifies concepts, such as “Convenient transportation in Shanghai” which is found to be more meaningful for KG construction. Each edge in the KG represents a relationship between concepts occurring in the same text chunk. The process is computationally inexpensive, leveraging locally set up tools like Mistral 7B openorca instruct and Ollama for model inference, ensuring the entire graph generation process is cost-free. A method of assigning weights to relationships, grouping similar pairs, and summarizing multiple relationships into a single edge with associated weight and relation details is introduced. Additionally, node degrees and communities are calculated for node sizing and coloring. This approach offers a scalable, cost-effective solution for generating meaningful knowledge graphs from large documents, achieving results comparable to GraphRAG while maintaining accessibility for personal machines.
基金supported by the National Research Foundation of Korea(NRF)grant funded by the Korean government(MSIT)(No.2020R1C1C1005567)supported by the NAVER Digital Bio Innovation Research Fund,funded by NAVER Corporation(Grant No.[37-2023-0040])+3 种基金supported by Institute of Information&communications Technology Planning&Evaluation(IITP)grant funded by the Korea government(MSIT)(No.2020-0-00261,Development of low power/low delay/self-power suppliable RF simultaneous information and power transfer system and stretchable electronic epineurium for wireless nerve bypass implementation)supported by Institute for Basic Science(IBS-R015-D1,IBSR015-D2)supported by a grant of the Korea-US Collaborative Research Fund(KUCRF)funded by the Ministry of Science and ICT and Ministry of Health&Welfare,Republic of Korea(Grant Number.RS-2024-00467213)。
文摘Prosthetic devices designed to assist individuals with damaged or missing body parts have made significant strides,particularly with advancements in machine intelligence and bioengineering.Initially focused on movement assistance,the field has shifted towards developing prosthetics that function as seamless extensions of the human body.During this progress,a key challenge remains the reduction of interface artifacts between prosthetic components and biological tissues.Soft electronics offer a promising solution due to their structural flexibility and enhanced tissue adaptability.However,achieving full integration of prosthetics with the human body requires both artificial perception and efficient transmission of physical signals.In this context,synaptic devices have garnered attention as next-generation neuromorphic computing elements because of their low power consumption,ability to enable hardware-based learning,and high compatibility with sensing units.These devices have the potential to create artificial pathways for sensory recognition and motor responses,forming a“sensory-neuromorphic system”that emulates synaptic junctions in biological neurons,thereby connecting with impaired biological tissues.Here,we discuss recent developments in prosthetic components and neuromorphic applications with a focus on sensory perception and sensorimotor actuation.Initially,we explore a prosthetic system with advanced sensory units,mechanical softness,and artificial intelligence,followed by the hardware implementation of memory devices that combine calculation and learning functions.We then highlight the importance and mechanisms of soft-form synaptic devices that are compatible with sensing units.Furthermore,we review an artificial sensory-neuromorphic perception system that replicates various biological senses and facilitates sensorimotor loops from sensory receptors,the spinal cord,and motor neurons.Finally,we propose insights into the future of closed-loop neuroprosthetics through the technical integration of soft electronics,including bio-integrated sensors and synaptic devices,into prosthetic systems.
基金supported by the Opening Foundation of China National Logging Corporation(CNLC20229C06)the China Petroleum Technical Service Corporation's science project'Development and application of 475 rotary steering system'(2024T-001001)。
文摘Rotary steering systems(RSSs)have been increasingly used to develop horizontal wells.A static push-the-bit RSS uses three hydraulic modules with varying degrees of expansion and contraction to achieve changes in the pushing force acting on the wellbore in different sizes and directions within a circular range,ultimately allowing the wellbore trajectory to be drilled in a predetermined direction.By analyzing its mathematical principles and the actual characteristics of the instrument,a vector force closed-loop control method,including steering and holding modes,was designed.The adjustment criteria for the three hydraulic modules are determined to achieve rapid adjustment of the vector force.The theoretical feasibility of the developed method was verified by comparing its results with the on-site application data of an imported rotary guidance system.
文摘Bariatric and metabolic surgeries have gained extensive popularity and trust due to their documented efficacy and safety in managing not only obesity but also associated comorbidities such as diabetes mellitus, hypertension, dyslipidemia, sleep apnea, and joint pain. Traditionally, bariatric surgeries have been categorized into hypoabsorptive, restrictive, or hybrid approaches. However, these classifications inadequately reflect the complex anatomical and physiological alterations associated with modern surgical methodologies. This paper explores the evolution of metabolic surgeries, emphasizing the integration of physiological concepts into classic procedures to provide more tailored and effective treatment options for obesity and its comorbidities. Finally, the proposal for a new classification based on current metabolic concepts will facilitate communication among patients, doctors, and healthcare professionals. Additionally, it will enable a more didactic and standardized approach to data collection for conducting studies and publications.
文摘Objectives:This study aimed to establish the concept of overcoming exhaustion,providing a reference basis for nursing management and conducting related nursing research.Methods:Liehr and Smith’s three-phase,nine-step concept-building process was used to create the concept of overcoming exhaustion.The nine steps were as follows:1)write a practice story;2)name the emerging concept;3)select a theoretical lens;4)link concept to literature;5)gather a concept story;6)identify final core qualities;7)formulate concept definition;8)create a concept model;and 9)specify the concept building synthesis.Results:The concept of overcoming exhaustion was identified based on the elements of a practice story,the life experiences of nurses who struggle with the demands of caring for their patients,their families,and themselves.The theory of self-transcendence was then recognized as the theoretical lens from which to ground the concept.The core qualities,despair and moments of calmness,were derived from the literature and confirmed through a concept story.A definition of the concept integrating the core qualities was formed:overcoming exhaustion involves realizing moments of calmness amidst despair.A model was created to demonstrate the relationship between core qualities,despair,and moments of calmness.Conclusions:The concept of overcoming exhaustion was developed and,through the concept-building process,was defined as realizing moments of calmness amidst despair.By identifying the complexities of overcoming exhaustion,this work lays the foundation for a future research program to develop understanding and interventions that support nurse well-being in the context of ongoing personal and professional demands.
文摘This paper mainly discusses the innovative teaching mode of translation for English Majors under the guidance of OBE education philosophy.Firstly,by analyzing the current situation of translation teaching for English majors,this paper points out the main problems,and combined with the OBE education concept,through optimizing the top-level design,updating the teaching content,improving the teaching methods,and scientifically using the evaluation methods,constructs a student-centered and outcome-oriented teaching mode.It is hoped that this study can improve students’translation ability and comprehensive quality,and provide a useful reference for the reform of translation teaching for English majors.
基金supported by the Henan Provincial Traditional Chinese Medicine Culture and Management Research Project(TCM2022036)Henan Provincial Traditional Chinese Medicine Culture Publication Funding Special Project(TCMCB2023016)+3 种基金Henan University of Chinese Medicine Research Seedling Project(MP2023-29)National Administration of Traditional Chinese Medicine Science and Technology Project(GZY-KJS-2022-043-1)Henan Culture-Promoting Project Cultural Research Special Project(2022XWH231)National Administration of Traditional Chinese Medicine Science and Technology Project(GZY-KJS-2022-037).
文摘By analyzing the structure and academic characteristics of early Western Han medical texts such as Prescriptions for Fifty-Two Diseases(Wu Shi Er Bing Fang)and Prescriptions for Health Preservation(Yang Sheng Fang),and considering the development of philosophical thinking during the pre-Qin and Han periods,this study summarizes how Zhongjing Zhang’s Treatise on Cold Damage and Miscellaneous Diseases(Shang Han Za Bing Lun)inherited pre-Qin and Han philosophical thought while further integrating Daoist“natural law”cosmology,Confucian“benevolence”social ethics,and the“isomorphic unity of heaven and humanity”medical theory in Yellow Emperor’s Inner Classic(Huang Di Nei Jing).It proposes health preservation concepts encompassing heaven-human,body-spirit,and benevolence perspectives,along with dietary hygiene,representing the medical embodiment of pre-Han“virtue cultivation”and“body nurturing”life philosophies that profoundly influenced subsequent traditional Chinese medicine health preservation theory and practice.
基金supported by the National Natural Science Foundation of China(Grant Nos.12372064 and 12172291)the Youth and Middle-Aged Science and Technology Development Program of Shanghai Institute of Technology(Grant No.ZQ2024-10)。
文摘Conventional open-loop deep brain stimulation(DBS)systems with fixed parameters fail to accommodate interindividual pathological differences in Parkinson's disease(PD)management while potentially inducing adverse effects and causing excessive energy consumption.In this paper,we present an adaptive closed-loop framework integrating a Yogi-optimized proportional–integral–derivative neural network(Yogi-PIDNN)controller.The Yogi-augmented gradient adaptation mechanism accelerates the convergence of general PIDNN controllers in high-dimensional nonlinear control systems while reducing control energy usage.In addition,a system identification method establishes input–output dynamics for pre-training stimulation waveforms,bypassing real-time parameter-tuning constraints and thereby enhancing closed-loop adaptability.Finally,a theoretical analysis based on Lyapunov stability criteria establishes a sufficient condition for closed-loop stability within the identified model.Computational validations demonstrate that our approach restores thalamic relay reliability while reducing energy consumption by(81.0±0.7)%across multi-frequency tests.This study advances adaptive neuromodulation by synergizing data-driven pre-training with stability-guaranteed real-time control,offering a novel framework for energy-efficient and personalized Parkinson's therapy.
基金supported by grants from the Higher Education Department of Jilin Provincial Department of Education(2024L5L93E80024).
文摘To define the concept of humanistic quality of nurses by Rodgers’evolutionary conceptual analysis.Based on Rodgers’s evolutionary concept analysis method as the theoretical basis to analyze the concept of humanistic literacy of nurses,the databases of CNKI,Wanfang,VIP,PubMed,Web of Science,and Science Direct were searched systematically from October 31st,2024.According to the inclusion and exclusion criteria,43 literatures were selected,including 34 Chinese literatures and 9 English literatures.Nurses’humanistic quality involved five conceptual attributes,including ethics,legal knowledge,traditional culture,interpersonal interaction,and aesthetic accomplishment.Antecedent variables include education environment,growth environment,hospital environment,and professional identity,and the consequences are divided into positive and negative aspects.Among them,positive consequences include harmonious nurse-patient relationships,efficient communication and cooperation,and improved nursing quality,while negative consequences include poor hospital operation,nurse-patient disputes,and reduced work quality.This paper defines and analyzes the humanistic qualities of nurses through the conceptual analysis of Rogers’theory of evolution,and the humanistic qualities of nurses refer to the comprehensive qualities of nurses based on ethics,legal knowledge,traditional culture,interpersonal interactions,and aesthetics in their professional practice,which will serve as a reference for future research in related fields.
