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A zinc-dependent switching mechanism from an open to a new closed-state conformation of insulin-degrading enzyme
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作者 Karina Abramov-Harpaz Yifat Miller 《Inorganic Chemistry Frontiers》 2021年第13期3205-3209,共5页
The switching mechanism between an open-state conformation and a newly closed-state conformation of IDE is stabilized by electrostatic interactions between domain D1 and domain D3.The loss of a Zn^(2+)ion at the catal... The switching mechanism between an open-state conformation and a newly closed-state conformation of IDE is stabilized by electrostatic interactions between domain D1 and domain D3.The loss of a Zn^(2+)ion at the catalytic zinc-binding site in the open-state conformation of IDE prevents the transition to the closed-state conformation. 展开更多
关键词 zinc dependent switching mechanism open state conformation insulin degrading enzyme switching mechanism domain d electrostatic interactions closed state conformation
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Critical Behavior of the Energy Gap and Its Relation with the Berry Phase Close to the Excited State Quantum Phase Transition in the Lipkin Model
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作者 袁子刚 张平 《Chinese Physics Letters》 SCIE CAS CSCD 2015年第6期1-5,共5页
In our previous work [Phys. Rev. A 85 (2012) 044102], we studied the Berry phase of the ground state and exited states in the Lipkin model. In this work, using the Hellmann-Feynman theorem, we derive the relation be... In our previous work [Phys. Rev. A 85 (2012) 044102], we studied the Berry phase of the ground state and exited states in the Lipkin model. In this work, using the Hellmann-Feynman theorem, we derive the relation between the energy gap and the Berry phase closed to the excited state quantum phase transition (ESQPT) in the Lipkin model. It is found that the energy gap is approximately linearly dependent on the Berry phase being closed to the ESQPT for large N. As a result, the critical behavior of the energy gap is similar to that of the Berry phase. In addition, we also perform a semiclassical qualitative analysis about the critical behavior of the energy gap. 展开更多
关键词 Critical Behavior of the Energy Gap and Its Relation with the Berry Phase Close to the Excited state Quantum Phase Transition in the Lipkin Model
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