In this paper, the double_moment of thin_wall cross_section spacial curved bars of anisotropic materials is discussed, and a general solving method for this type of problems as well as the concrete double_moment formu...In this paper, the double_moment of thin_wall cross_section spacial curved bars of anisotropic materials is discussed, and a general solving method for this type of problems as well as the concrete double_moment formula of planary curved bars subjected to action of vertical loads are given out.展开更多
Microglial activation that occurs rapidly after closed head injury may play important and complex roles in neuroinflammation-associated neuronal damage and repair.We previously reported that induced neural stem cells ...Microglial activation that occurs rapidly after closed head injury may play important and complex roles in neuroinflammation-associated neuronal damage and repair.We previously reported that induced neural stem cells can modulate the behavior of activated microglia via CXCL12/CXCR4 signaling,influencing their activation such that they can promote neurological recovery.However,the mechanism of CXCR4 upregulation in induced neural stem cells remains unclear.In this study,we found that nuclear factor-κB activation induced by closed head injury mouse serum in microglia promoted CXCL12 and tumor necrosis factor-αexpression but suppressed insulin-like growth factor-1 expression.However,recombinant complement receptor 2-conjugated Crry(CR2-Crry)reduced the effects of closed head injury mouse serum-induced nuclear factor-κB activation in microglia and the levels of activated microglia,CXCL12,and tumor necrosis factor-α.Additionally,we observed that,in response to stimulation(including stimulation by CXCL12 secreted by activated microglia),CXCR4 and Crry levels can be upregulated in induced neural stem cells via the interplay among CXCL12/CXCR4,Crry,and Akt signaling to modulate microglial activation.In agreement with these in vitro experimental results,we found that Akt activation enhanced the immunoregulatory effects of induced neural stem cell grafts on microglial activation,leading to the promotion of neurological recovery via insulin-like growth factor-1 secretion and the neuroprotective effects of induced neural stem cell grafts through CXCR4 and Crry upregulation in the injured cortices of closed head injury mice.Notably,these beneficial effects of Akt activation in induced neural stem cells were positively correlated with the therapeutic effects of induced neural stem cells on neuronal injury,cerebral edema,and neurological disorders post–closed head injury.In conclusion,our findings reveal that Akt activation may enhance the immunoregulatory effects of induced neural stem cells on microglial activation via upregulation of CXCR4 and Crry,thereby promoting induced neural stem cell–mediated improvement of neuronal injury,cerebral edema,and neurological disorders following closed head injury.展开更多
Objective The relationship between non-high-density lipoprotein(NHDL)cholesterol to high-density lipoprotein cholesterol(HDL-C)ratio(NHHR)and stoke remains unknown.This study aimed to evaluate the association between ...Objective The relationship between non-high-density lipoprotein(NHDL)cholesterol to high-density lipoprotein cholesterol(HDL-C)ratio(NHHR)and stoke remains unknown.This study aimed to evaluate the association between the adult NHHR and stroke occurrence in the United States of America(USA).Methods To clarify the relationship between the NHHR and stroke risk,this study used a multivariable logistic regression model and a restricted cubic spline(RCS)model to investigate the association between the NHHR and stroke,and data from the National Health and Nutrition Examination Survey(NHANES)from 2005 to 2018.Subgroup and sensitivity analyses were conducted to test the robustness of the results.Results This study included 29,928 adult participants,of which 1,165 participants had a history of stroke.Logistic regression analysis of variables demonstrated a positive association between NHHR and stroke(OR 1.24,95%CI:1.03-1.50,P=0.026).Compared with the lowest reference group of NHHR,participants in the second,third,and fourth quartile had a significantly increased risk of stroke after full adjustments(OR:1.35,95%CI:1.08-1.69)(OR:1.83,95%CI:1.42-2.36)(OR:2.04,95%CI:1.50-2.79).In the total population,a nonlinear dose-response relationship was observed between the NHHR and stroke risk(P non-linearity=0.002).This association remained significant in several subgroup analyses.Further investigation of the NHHR may enhance our understanding of stroke prevention and treatment.Conclusion Our findings suggest a positive correlation between the NHHR and an increased prevalence of stroke,potentially serving as a novel predictive factor for stroke.Timely intervention and management of the NHHR may effectively mitigate stroke occurrence.Prospective studies are required to validate this association and further explore the underlying biological mechanisms.展开更多
The umbilical,a key component in offshore energy extraction,plays a vital role in ensuring the stable operation of the entire production system.The extensive variety of cross-sectional components creates highly comple...The umbilical,a key component in offshore energy extraction,plays a vital role in ensuring the stable operation of the entire production system.The extensive variety of cross-sectional components creates highly complex layout combinations.Furthermore,due to constraints in component quantity and geometry within the cross-sectional layout,filler bodies must be incorporated to maintain cross-section performance.Conventional design approaches based on manual experience suffer from inefficiency,high variability,and difficulties in quantification.This paper presents a multi-level automatic filling optimization design method for umbilical cross-sectional layouts to address these limitations.Initially,the research establishes a multi-objective optimization model that considers compactness,balance,and wear resistance of the cross-section,employing an enhanced genetic algorithm to achieve a near-optimal layout.Subsequently,the study implements an image processing-based vacancy detection technique to accurately identify cross-sectional gaps.To manage the variability and diversity of these vacant regions,the research introduces a multi-level filling method that strategically selects and places filler bodies of varying dimensions,overcoming the constraints of uniform-size fillers.Additionally,the method incorporates a hierarchical strategy that subdivides the complex cross-section into multiple layers,enabling layer-by-layer optimization and filling.This approach reduces manufac-turing equipment requirements while ensuring practical production process feasibility.The methodology is validated through a specific umbilical case study.The results demonstrate improvements in compactness,balance,and wear resistance compared with the initial cross-section,offering novel insights and valuable references for filler design in umbilical cross-sections.展开更多
Rationally regulating the porosity of hard carbon(HC),especially the closed pores matching the low potential plateau and the ultra-microporous structure suitable for Na+embedding,has been shown to be the key to improv...Rationally regulating the porosity of hard carbon(HC),especially the closed pores matching the low potential plateau and the ultra-microporous structure suitable for Na+embedding,has been shown to be the key to improving the sodium storage performance and initial coulombic efficiency(ICE).However,the preparation of such HC materials with specific pore structures still faces great challenges.Herein,a simple pre-oxidation strategy is employed to construct abundant closed ultra-microporous structures in soy protein powder-derived HC material,achieving a significant improvement in its ICE and platform capacity.The pre-oxidation process promotes the cross-linking degree of the soy protein,thereby hindering the directional growth of graphite domains during the carbonization process.The optimized HC exhibits ultra-high platform capacity(329 mAh g^(-1))and considerable energy density(148.5 Wh kg^(-1)).Based on the ex-situ Raman and X-ray photoelectron spectroscopy characterization results,the excellent sodium storage capacity of the HC material is attributed to the synergistic effect of adsorption-intercalation/filling.The presented work provides novel insights into the synthesis of other biomass-derived HC materials with abundant closed ultra-micro pores.展开更多
Objective:Postpartum nutrition plays a critical role in maternal recovery and long-term health.However,the nutritional status of working mothers in the postpartum period remains understudied.This study aimed to assess...Objective:Postpartum nutrition plays a critical role in maternal recovery and long-term health.However,the nutritional status of working mothers in the postpartum period remains understudied.This study aimed to assess the dietary quality of postpartum women in urban Beijing,identify occupational-related factors influencing their diet,and explore potential interventions to improve maternal nutrition during the postpartum period.Methods:In this cross-sectional analysis,554 women one year after delivery were recruited from ten community health centers.Sociodemographic,occupational and postpartum care variables were collected via questionnaire.Dietary intake over the preceding year was assessed using a food frequency questionnaire.The modified dietary balance index for postpartum women were used for dietary quality assessment.Results:The study revealed severe dietary imbalances among postpartum women,characterized by excessive consumption of cereals,eggs,and meats,while their intake of vegetables,fruits,and dairy products was inadequate.According to dietary balance index for postpartum women,66.25%of mothers showed varying degrees of excessive intake.45.31%of mothers experienced varying levels of insufficient intake,with only 19.86%of participants having a relatively balanced diet.Occupational differences were observed,with women in the commercial employment group showing higher levels of excessive food intake.The analysis of influencing factors showed that family monthly income,maternity leave,and postpartum care significantly affected the dietary quality.Conclusions:Postpartum women in Beijing experience widespread dietary imbalances,with both excesses and deficiencies.Occupational context and related factors significantly shape diet quality.These findings highlight the need for targeted nutritional interventions tailored to the specific challenges of different occupational groups.展开更多
Background:The bibliometrics of acupuncture are growing rapidly.However,the absence of reporting guidelines may lead to significant duplication and waste,thereby undermining the research’s value.To address this,a kno...Background:The bibliometrics of acupuncture are growing rapidly.However,the absence of reporting guidelines may lead to significant duplication and waste,thereby undermining the research’s value.To address this,a knowledge mapping was generated based on published studies to investigate the characteristics of bibliometric studies on acupuncture and the extent of duplicate publications,with the overarching goal of providing a comprehensive overview of the knowledge structure in this field.Methods:This cross-sectional study used three databases(PubMed,Web of Science,and Scopus)to identify relevant studies up to May 1,2024.In addition,the reference lists were retrieved as a supplement.To track research trends,we employed Microsoft Excel and R software to extract,code,and analyze information.Study selection,data extraction,and validation were performed independently by at least two reviewers.The reporting quality of included studies was assessed using the Preliminary guideline for reporting bibliometric reviews of the biomedical literature(BIBLIO).Results:Among the 6,221 bibliometric reviews examined,113 relevant publications were identified,80 focusing on various diseases/conditions.The annual number of publications has gradually increased,with the output in the past four years being 3.52 times higher than that before 2020.China(106)and Chengdu University of Traditional Chinese Medicine(16)have the highest number of publications.The most prolific author is Fan-Rong Liang,with six articles.The first bibliometric study,by Hai-Yan Li,was published in 2010.Journal of Pain Research,with 36 articles,holds the most publications.The top three diseases:diseases of the nervous system;symptoms,signs,or clinical findings not elsewhere classified;and mental,behavioral,or neurodevelopmental disorders.There may be potential duplication in research on 13 diseases/conditions,notably stroke,migraine,pain/analgesia,cancer pain,shoulder pain,facial paralysis/bell’s palsy,chronic pain,and cognitive impairment.In BIBLIO,the most frequently missing items are issues/topics(item 2),quality assessment(item 11),and descriptive findings(item 13).Conclusion:This study demonstrates that acupuncture bibliometrics is actively utilized to identify dominant diseases/conditions,aiding scholars in understand the knowledge structure and main topics.Although the number of related studies is increasing,with an average of 25 studies annually,overlap in some areas highlights the need for adherence to reporting guidelines and careful topic selection to ensure truly valuable insights and knowledge contributions.The adherence to BIBLIO’s 20 proposed items across analyzed articles,highlighting important in reporting practices.展开更多
Objectives:This study aimed to classify young breast cancer patients into distinct ambivalence over emotional expression and to explore the factors influencingthe level of ambivalence over emotional expression.Methods...Objectives:This study aimed to classify young breast cancer patients into distinct ambivalence over emotional expression and to explore the factors influencingthe level of ambivalence over emotional expression.Methods:A total of 217 young breast cancer patients were enrolled from a tertiary Grade A oncology hospital in Tianjin,China,using the convenience sampling method.All participants completed the general questionnaire,Ambivalence over Emotion Expression Questionnaire(AEQ),and Family Adapt-Ability and Cohesion Evaluation Scales-Chinese Version(FACES-CV).We employed exploratory latent profileanalysis for ambivalence over emotional expression profilingand logistic regression analysis to identify the influentialfactors Results:The results of the latent profileanalysis supported the models of four latent profiles,which were definedas“low conflict-lowexpression reflection”(19.2%),“high conflict-high inhibition expression”(43.9%),“moderate conflict-highregret expression”(18.1%),and“moderate conflict-desire understand”(18.8%).Logistic regression revealed that family cohesion,marital status,residence,per capita monthly income,and cancer stage were the influencingfactors of ambivalence over emotional expression in young breast cancer patients(P<0.05)Conclusions:Levels of ambivalence over emotional expression ameast cancer patients with breast cancer were highly heterogeneous.Medical staff should provide psychological counseling and health education tailored to the unique characteristics of emotional expression ambivalence in different patient groups to promote healthy emotional expression among patients.展开更多
Hard carbon(HC)is considered the most promising anode material for sodium-ion batteries(SIBs)due to its high costeffectiveness and outstanding overall performance.However,the amorphous and intricate microstructure of ...Hard carbon(HC)is considered the most promising anode material for sodium-ion batteries(SIBs)due to its high costeffectiveness and outstanding overall performance.However,the amorphous and intricate microstructure of HC poses significant challenges in elucidating the structure-performance relationship,which has led to persistent misinterpretations regarding the intrinsic characteristics of closed pores.An irrational construction methodology of closed pores inevitably results in diminished plateau capacity,which severely restricts the practical application of HC in high-energy-density scenarios.This review provides a systematic exposition of the conceptual framework and origination mechanisms of closed pores,offering critical insights into their structural characteristics and formation pathways.Subsequently,by correlating lattice parameters with defect configurations,the structure-performance relationships governing desolvation kinetics and sodium storage behavior are rigorously established.Furthermore,pioneering advancements in structural engineering are critically synthesized to establish fundamental design principles for the rational modulation of closed pores in HC.It is imperative to emphasize that adopting a molecular-level perspective,coupled with a synergistic kinetic/thermodynamic approach,is critical for understanding and controlling the transformation process from open pores to closed pores.These innovative perspectives are strategically designed to accelerate the commercialization of HC,thereby catalyzing the sustainable and high-efficiency development of SIBs.展开更多
Objective:This study aimed to examine the association between parent-child relationships and physically aggressive behavior among adolescents.Methods:This is a cross-sectional study that uses secondary data from the 2...Objective:This study aimed to examine the association between parent-child relationships and physically aggressive behavior among adolescents.Methods:This is a cross-sectional study that uses secondary data from the 2015 Indonesia Global School-Based Health Survey(IGSHS).Health surveys were conducted in 75 schools representing three regions(Sumatra,Java-Bali;Outer Sumatra;and Java-Bali)in 26 provinces and 68 districts/cities in Indonesia(N=10,139 students).Students who participated were aged 12-19 years,were enrolled in public schools in the junior and high school levels.Results:It has been seen that for most middle-aged adolescents(58.7%),their parents(25%-29%)pay less attention to academic assignments(homework),problems,and use of free time.The most significant factors that influence adolescents to commit violence are smoking and consuming alcohol.Adolescents who smoke are twice as likely to commit physical violence compared with adolescents who do not smoke(OR=2.005;95%CI=1.7062-2.396).Meanwhile,adolescents who consume alcohol are 1.8 times more likely to commit physical violence compared with adolescents who do not consume alcohol(OR=1.807;95%CI=1.421-2.298).Conclusions:Through educational activities and consultations,this study’s findings are valuable for establishing parenting programs among those concerned about their children’s aggressive behavior.Meanwhile,counseling programs can be started in schools by conducting self-detection of negative adolescent behavior,such as screening for smoking,alcohol consumption,sleep issues,and attempted suicide.展开更多
In conventional piezoelectric micromachined ultrasonic transducers(PMUTs),the backside acoustic energy is often used inefficiently,resulting in up to half of the energy being wasted.Vacuum encapsulation can improve th...In conventional piezoelectric micromachined ultrasonic transducers(PMUTs),the backside acoustic energy is often used inefficiently,resulting in up to half of the energy being wasted.Vacuum encapsulation can improve the energy utilization efficiency,but this technique is not compatible with state-of-the-art devices such as cantilever-based PMUTs.A closed back cavity provides an alternative method for effectively utilizing the backside acoustic energy.This paper investigates the effects of a closed back cavity on PMUT performance through theoretical analysis,simulations,and experimental verification.Increasing the cavity depth produces a periodic modulation of several key PMUT metrics,such as the relative frequency deviation and quality factor.The optimal cavity depth for PMUTs that ensures a robust resonant frequency and high quality factor is defined as a function of the acoustic wavelength.A closed back cavity also provides an effective method for continuously tuning the quality factor,and thus the bandwidth,of PMUTs.This work paves the way for air-coupled PMUTs with adjustable performance for various applications.展开更多
Loess is susceptible to loading effects such as significant changes in strength and volume variation caused by loading and wetting.In this study,considering the different connection states of pore water and gas in loe...Loess is susceptible to loading effects such as significant changes in strength and volume variation caused by loading and wetting.In this study,considering the different connection states of pore water and gas in loess fabric,the gas phase closure case is incorporated into a unified form of the generalized effective stress framework,introducing a damage parameter considering the effects of closed pore gas.The loading effects of unsaturated loess under wide variations in saturation are described in a unified way,and the model performance is verified by corresponding stress and hydraulic path tests.The results indicated that the collapse response involves the initial void ratio of loess,and the coupled outwards motion of the loading-collapse(LC)yield surface under loading enhances its structural strength.Suction-enhanced yield stress requires a greater"tensile stress"to counteract its structural stability.The nucleation of bubbles at high saturation causes a decrease in yield stress.The loading effect exhibits a smaller collapse behavior when the influence of closed gas is considered,whereas the suction path does not cross the LC in the stress space under hydraulic action for the same parameters,which amplifies the influence of closed gas on loess deformation.展开更多
Objective:To study the relationship between qi stagnation constitution and suboptimal health status(SHS)or lifestyle.Methods:From 2012 to 2013,we conducted a cross-sectional survey of 24159 Chinese individuals aged 12...Objective:To study the relationship between qi stagnation constitution and suboptimal health status(SHS)or lifestyle.Methods:From 2012 to 2013,we conducted a cross-sectional survey of 24159 Chinese individuals aged 12-80 years.The qi stagnation constitution was assessed using the Constitution in Chinese Medicine Questionnaire.Health status was evaluated through medical records and the Subhealth Measurement Scale V1.0(SHMS V1.0).Health-promoting lifestyles were measured using the Health-Promoting Lifestyle Profile Ⅱ(HPLP-Ⅱ).Results:Of the 24159 participants,16.1%and 15.2%were classified as“always”and“sometimes”having the qi stagnation constitution,respectively.Those classified as“rarely”having the qi stagnation constitution scored higher on both the HPLP-Ⅱ and SHMS V1.0.The participants classified as“always”having the qi stagnation constitution showed a significant association with SHS or disease compared to other imbalanced constitutions.Those in the“always”category were approximately 21 times more likely to be classified as having SHS(odds ratio[OR]:21.17,95%confidence interval[CI]:15.74-28.45),whereas those in the“sometimes”category were approximately six times more likely(OR:5.89,95%CI:5.04-6.90).Accordingly,the qi stagnation constitution score was significantly associated with the diagnosis of SHS,with an area under the curve of 0.77(P<.001).A score of 18.75 yielded the highest Youden Index(0.407),with a sensitivity of 60.5%and a specificity of 80.3%.Significant associations were observed between health-promoting lifestyles and qi stagnation constitution severity in an ordinal regression analysis(P<.001).Protective factors included stress management(OR:1.59),self-actualization(OR:1.57),and exercise(OR:1.36).In contrast,poorer interpersonal relationships(OR:0.79),greater health responsibilities(OR:0.86),and poorer nutrition(OR:0.91)were associated with increased severity.Conclusion:Modulating the qi stagnation constitution through lifestyle interventions may help prevent the progression of SHS to disease,which aligns with core preventive principles in traditional Chinese medicine.展开更多
Objective Close reduction and internal fixation have gained popularity for the treatment of pelvic fractures.However,the closed reduction of bilateral displaced posterior pelvic ring disruption is a great challenge ev...Objective Close reduction and internal fixation have gained popularity for the treatment of pelvic fractures.However,the closed reduction of bilateral displaced posterior pelvic ring disruption is a great challenge even for the most experienced surgeon.In this study,we describe in detail a novel unlocking closed reduction technique(UCRT)frame that allows strong traction for bilateral posterior pelvic ring displacement and presents preliminary clinical outcomes.Methods We retrospectively reviewed 32 patients with bilateral displaced posterior pelvic ring disruptions(AO/OTA 61-C2 and C3)who were initially treated with this technique between July 2017 and July 2022.According to the AO/OTA clas-sification,there were 9 cases(28.12%)of 61-C2,and 23 cases(71.88%)of 61-C3.There were 11 males,21 females,with an average age of 38.1 years.The interval from injury to operation was 4-27 days,with a cut-off of 12.5 days(receiver operat-ing characteristic curve).Operative time,blood loss,and postoperative radiographic findings were recorded.The functional outcomes and complications were followed.Results A total of 30(93.8%)patients achieved successful closed reduction,whereas 2 required open reduction.The success-ful closed reduction rate was 95.5%(21/22)in patients whose injury-to-operation time was less than 12.5 days.The vertical displacement percent correction of the obviously displaced hemipelvis was 70.20%±16.79%on average.The average degree of pelvic deformity correction was 64.86%±17.71%.Thirty patients were followed up for at least 12 months(12-36 months),and no complications of nonunion or redisplacement were observed.The Matta-Tornetta scoring standard revealed that the excellent(25/30)and good(4/30)rate was 96.7%.The Majeed clinical efficacy score revealed that the overall excellent and good rate was 100%.One patient had INFIX-related infection,and 2 reported numbness in the lateral thigh.The numbness was improved after INFIX removal.Conclusions This study presents an updated technique for closed reduction using a UCRT frame for bilateral posterior pelvic ring disruption,which has been shown to be effective,as indicated by excellent surgical and functional outcomes.展开更多
The scroll expander,as the core component of the micro-compressed air energy storage and power generation system,directly affects the output efficiency of the system.Meanwhile,the scroll profile plays a central role i...The scroll expander,as the core component of the micro-compressed air energy storage and power generation system,directly affects the output efficiency of the system.Meanwhile,the scroll profile plays a central role in determining the output performance of the scroll expander.In this study,in order to investigate the output characteristics of a variable cross-section scroll expander,numerical simulation and experimental studies were con-ducted by using Computational Fluid Dynamics(CFD)methods and dynamic mesh techniques.The impact of critical parameters on the output performance of the scroll expander was analyzed through the utilization of the control variable method.It is found that increasing the inlet pressure and temperature within a certain range can improve the output power of the scroll expander.However,the increase in temperature and meshing clearance leads to a decline in the overall output performance of the scroll expander,leading to a decrease in volumetric efficiency by 8.43%and 12.79%,respectively.The experiments demonstrate that under equal inlet pressure conditions,increasing the inlet temperature elevates both the rotational speed and torque output of the scroll expander.Specifically,compared to operating at normal temperatures,the output torque increases by 21.8%under high-temperature conditions.However,the rate of speed and torque variation decreases as a consequence of enlarged meshing clearance,resulting in increased internal leakage and reduction in isentropic efficiency.展开更多
OBJECTIVE:To investigate the difference in gut microbiota between population with damp-heat constitution(DHC)and balanced constitution(BC).METHODS:A multi-centered cross-sectional casecontrol study was conducted,which...OBJECTIVE:To investigate the difference in gut microbiota between population with damp-heat constitution(DHC)and balanced constitution(BC).METHODS:A multi-centered cross-sectional casecontrol study was conducted,which included 249 participants with damp-heat constitution or balanced constitution.Baseline information of participants was collected,and stool samples were collected for gut microbiota analysis.Principal coordinate analysis,linear discriminant analysis effect size analysis,receiver operating characteristic,random forest model,and phylogenetic investigation of communities by reconstruction of unobserved states methods were used to reveal the relationship between gut microbiota and the damp-heat constitution.RESULTS:Compared to those in the BC group,the richness and diversity of the microbiota,specifically those of several short-chain fatty acid producing genera such as Barnesiella,Coprobacter,and Butyricimonas,were significantly decreased in the DHC group.Regarding biological functions,flavonoid biosynthesis,propanoate metabolism,and nucleotide sugar metabolism were suppressed,while arachidonic acid metabolism and glutathione metabolism were enriched in the DHC group.Finally,a classifier based on the microbiota was constructed to discriminate between the DHC and BC populations.CONCLUSION:The gut microbiota of the DHC population exhibits significantly reduced diversity and is closely related to inflammation,metabolic disorders,and liver steatosis,which is consistent with clinical observations,thus serving as a potential diagnostic tool for traditional Chinese medicine constitution discrimination.展开更多
To investigate the effects of the maximum principal stress direction(θ)and cross-section shape on the failure characteristics of sandstone,true-triaxial compression experiments were conducted using cubic samples with...To investigate the effects of the maximum principal stress direction(θ)and cross-section shape on the failure characteristics of sandstone,true-triaxial compression experiments were conducted using cubic samples with rectangular,circular,and D-shaped holes.Asθincreases from 0°to 60°in the rectangular hole,the left failure location shifts from the left corner to the left sidewall,the left corner,and then the floor,while the right failure location shifts from the right corner to the right sidewall,right roof corner,and then the roof.Furthermore,the initial failure vertical stress first decreases and then increases.In comparison,the failure severity in the rectangular hole decreases for variousθvalues as 30°>45°>60°>0°.With increasingθ,the fractal dimension(D)of rock slices first increases and then decreases.For the rectangular and D-shaped holes,whenθ=0°,30°,and 90°,D for the rectangular hole is less than that of the D-shaped hole.Whenθ=45°and 60°,D for the rectangular hole is greater than that of the D-shaped hole.Theoretical analysis indicates that the stress concentration at the rectangular and D-shaped corners is greater than the other areas.The failure location rotates with the rotation ofθ,and the failure occurs on the side with a high concentration of compressive stress,while the side with the tensile and compressive stresses remains relatively stable.Therefore,the fundamental reason for the rotation of failure location is the rotation of stress concentration,and the external influencing factor is the rotation ofθ.展开更多
In this article,we are concerned with the C^(2)estimates for the k-convex solutions of a class of degenerate k-Hessian equations on closed Hermitian manifolds,whose function in the right-hand side is relevant to the u...In this article,we are concerned with the C^(2)estimates for the k-convex solutions of a class of degenerate k-Hessian equations on closed Hermitian manifolds,whose function in the right-hand side is relevant to the unknown function and its gradient.We will get C^(0)estimate by promoting others′results,and get the“HMW estimate”of this equation such that the conditions of using blow-up analysis are satisfied,and the gradient estimate and second-order estimate will be obtained.Such an estimate will be helpful to study the existence for the solution of the equation.展开更多
This study introduces a novel method for reconstructing the 3D model of aluminum foam using cross-sectional sequence images.Combining precision milling and image acquisition,high-qual-ity cross-sectional images are ob...This study introduces a novel method for reconstructing the 3D model of aluminum foam using cross-sectional sequence images.Combining precision milling and image acquisition,high-qual-ity cross-sectional images are obtained.Pore structures are segmented by the U-shaped network(U-Net)neural network integrated with the Canny edge detection operator,ensuring accurate pore delineation and edge extraction.The trained U-Net achieves 98.55%accuracy.The 2D data are superimposed and processed into 3D point clouds,enabling reconstruction of the pore structure and aluminum skeleton.Analysis of pore 01 shows the cross-sectional area initially increases,and then decreases with milling depth,with a uniform point distribution of 40 per layer.The reconstructed model exhibits a porosity of 77.5%,with section overlap rates between the 2D pore segmentation and the reconstructed model exceeding 96%,confirming high fidelity.Equivalent sphere diameters decrease with size,averaging 1.95 mm.Compression simulations reveal that the stress-strain curve of the 3D reconstruction model of aluminum foam exhibits fluctuations,and the stresses in the reconstruction model concentrate on thin cell walls,leading to localized deformations.This method accurately restores the aluminum foam’s complex internal structure,improving reconstruction preci-sion and simulation reliability.The approach offers a cost-efficient,high-precision technique for optimizing material performance in engineering applications.展开更多
文摘In this paper, the double_moment of thin_wall cross_section spacial curved bars of anisotropic materials is discussed, and a general solving method for this type of problems as well as the concrete double_moment formula of planary curved bars subjected to action of vertical loads are given out.
基金supported by the National Natural Science Foundation of China,Nos.82271397(to MG),82001293(to MG),82171355(to RX),81971295(to RX),and 81671189(to RX)。
文摘Microglial activation that occurs rapidly after closed head injury may play important and complex roles in neuroinflammation-associated neuronal damage and repair.We previously reported that induced neural stem cells can modulate the behavior of activated microglia via CXCL12/CXCR4 signaling,influencing their activation such that they can promote neurological recovery.However,the mechanism of CXCR4 upregulation in induced neural stem cells remains unclear.In this study,we found that nuclear factor-κB activation induced by closed head injury mouse serum in microglia promoted CXCL12 and tumor necrosis factor-αexpression but suppressed insulin-like growth factor-1 expression.However,recombinant complement receptor 2-conjugated Crry(CR2-Crry)reduced the effects of closed head injury mouse serum-induced nuclear factor-κB activation in microglia and the levels of activated microglia,CXCL12,and tumor necrosis factor-α.Additionally,we observed that,in response to stimulation(including stimulation by CXCL12 secreted by activated microglia),CXCR4 and Crry levels can be upregulated in induced neural stem cells via the interplay among CXCL12/CXCR4,Crry,and Akt signaling to modulate microglial activation.In agreement with these in vitro experimental results,we found that Akt activation enhanced the immunoregulatory effects of induced neural stem cell grafts on microglial activation,leading to the promotion of neurological recovery via insulin-like growth factor-1 secretion and the neuroprotective effects of induced neural stem cell grafts through CXCR4 and Crry upregulation in the injured cortices of closed head injury mice.Notably,these beneficial effects of Akt activation in induced neural stem cells were positively correlated with the therapeutic effects of induced neural stem cells on neuronal injury,cerebral edema,and neurological disorders post–closed head injury.In conclusion,our findings reveal that Akt activation may enhance the immunoregulatory effects of induced neural stem cells on microglial activation via upregulation of CXCR4 and Crry,thereby promoting induced neural stem cell–mediated improvement of neuronal injury,cerebral edema,and neurological disorders following closed head injury.
文摘Objective The relationship between non-high-density lipoprotein(NHDL)cholesterol to high-density lipoprotein cholesterol(HDL-C)ratio(NHHR)and stoke remains unknown.This study aimed to evaluate the association between the adult NHHR and stroke occurrence in the United States of America(USA).Methods To clarify the relationship between the NHHR and stroke risk,this study used a multivariable logistic regression model and a restricted cubic spline(RCS)model to investigate the association between the NHHR and stroke,and data from the National Health and Nutrition Examination Survey(NHANES)from 2005 to 2018.Subgroup and sensitivity analyses were conducted to test the robustness of the results.Results This study included 29,928 adult participants,of which 1,165 participants had a history of stroke.Logistic regression analysis of variables demonstrated a positive association between NHHR and stroke(OR 1.24,95%CI:1.03-1.50,P=0.026).Compared with the lowest reference group of NHHR,participants in the second,third,and fourth quartile had a significantly increased risk of stroke after full adjustments(OR:1.35,95%CI:1.08-1.69)(OR:1.83,95%CI:1.42-2.36)(OR:2.04,95%CI:1.50-2.79).In the total population,a nonlinear dose-response relationship was observed between the NHHR and stroke risk(P non-linearity=0.002).This association remained significant in several subgroup analyses.Further investigation of the NHHR may enhance our understanding of stroke prevention and treatment.Conclusion Our findings suggest a positive correlation between the NHHR and an increased prevalence of stroke,potentially serving as a novel predictive factor for stroke.Timely intervention and management of the NHHR may effectively mitigate stroke occurrence.Prospective studies are required to validate this association and further explore the underlying biological mechanisms.
基金financially supported by Guangdong Province Basic and Applied Basic Research Fund Project(Grant No.2022B1515250009)Liaoning Provincial Natural Science Foundation-Doctoral Research Start-up Fund Project(Grant No.2024-BSBA-05)+1 种基金Major Science and Technology Innovation Project in Shandong Province(Grant No.2024CXGC010803)the National Natural Science Foundation of China(Grant Nos.52271269 and 12302147).
文摘The umbilical,a key component in offshore energy extraction,plays a vital role in ensuring the stable operation of the entire production system.The extensive variety of cross-sectional components creates highly complex layout combinations.Furthermore,due to constraints in component quantity and geometry within the cross-sectional layout,filler bodies must be incorporated to maintain cross-section performance.Conventional design approaches based on manual experience suffer from inefficiency,high variability,and difficulties in quantification.This paper presents a multi-level automatic filling optimization design method for umbilical cross-sectional layouts to address these limitations.Initially,the research establishes a multi-objective optimization model that considers compactness,balance,and wear resistance of the cross-section,employing an enhanced genetic algorithm to achieve a near-optimal layout.Subsequently,the study implements an image processing-based vacancy detection technique to accurately identify cross-sectional gaps.To manage the variability and diversity of these vacant regions,the research introduces a multi-level filling method that strategically selects and places filler bodies of varying dimensions,overcoming the constraints of uniform-size fillers.Additionally,the method incorporates a hierarchical strategy that subdivides the complex cross-section into multiple layers,enabling layer-by-layer optimization and filling.This approach reduces manufac-turing equipment requirements while ensuring practical production process feasibility.The methodology is validated through a specific umbilical case study.The results demonstrate improvements in compactness,balance,and wear resistance compared with the initial cross-section,offering novel insights and valuable references for filler design in umbilical cross-sections.
基金supported by the National Natural Science Foundation of China(42167068,22269020)the Gansu Province Higher Education Industry Support Plan Project(2023CYZC-68)the Central Guidance for Local Science and Technology Development Funds Project(YDZX20216200001007)。
文摘Rationally regulating the porosity of hard carbon(HC),especially the closed pores matching the low potential plateau and the ultra-microporous structure suitable for Na+embedding,has been shown to be the key to improving the sodium storage performance and initial coulombic efficiency(ICE).However,the preparation of such HC materials with specific pore structures still faces great challenges.Herein,a simple pre-oxidation strategy is employed to construct abundant closed ultra-microporous structures in soy protein powder-derived HC material,achieving a significant improvement in its ICE and platform capacity.The pre-oxidation process promotes the cross-linking degree of the soy protein,thereby hindering the directional growth of graphite domains during the carbonization process.The optimized HC exhibits ultra-high platform capacity(329 mAh g^(-1))and considerable energy density(148.5 Wh kg^(-1)).Based on the ex-situ Raman and X-ray photoelectron spectroscopy characterization results,the excellent sodium storage capacity of the HC material is attributed to the synergistic effect of adsorption-intercalation/filling.The presented work provides novel insights into the synthesis of other biomass-derived HC materials with abundant closed ultra-micro pores.
基金supported by an Innovation Fund for Medical Sciences of the Chinese Academy of Medical Sciences (Grant No.2019-I2M-2-007).
文摘Objective:Postpartum nutrition plays a critical role in maternal recovery and long-term health.However,the nutritional status of working mothers in the postpartum period remains understudied.This study aimed to assess the dietary quality of postpartum women in urban Beijing,identify occupational-related factors influencing their diet,and explore potential interventions to improve maternal nutrition during the postpartum period.Methods:In this cross-sectional analysis,554 women one year after delivery were recruited from ten community health centers.Sociodemographic,occupational and postpartum care variables were collected via questionnaire.Dietary intake over the preceding year was assessed using a food frequency questionnaire.The modified dietary balance index for postpartum women were used for dietary quality assessment.Results:The study revealed severe dietary imbalances among postpartum women,characterized by excessive consumption of cereals,eggs,and meats,while their intake of vegetables,fruits,and dairy products was inadequate.According to dietary balance index for postpartum women,66.25%of mothers showed varying degrees of excessive intake.45.31%of mothers experienced varying levels of insufficient intake,with only 19.86%of participants having a relatively balanced diet.Occupational differences were observed,with women in the commercial employment group showing higher levels of excessive food intake.The analysis of influencing factors showed that family monthly income,maternity leave,and postpartum care significantly affected the dietary quality.Conclusions:Postpartum women in Beijing experience widespread dietary imbalances,with both excesses and deficiencies.Occupational context and related factors significantly shape diet quality.These findings highlight the need for targeted nutritional interventions tailored to the specific challenges of different occupational groups.
文摘A survey of recent progress on the multiplicity and stability problems for closed characteristics on compact convex hypersurfaces in R^(2n) is given.
基金supported by the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(ZYYCXTD-C-202006)the High-level traditional Chinese medicine key subject construction project of National Administration of Traditional Chinese Medicine-Evidence-based Traditional Chinese Medicine(ZYYZDXK-2023249).
文摘Background:The bibliometrics of acupuncture are growing rapidly.However,the absence of reporting guidelines may lead to significant duplication and waste,thereby undermining the research’s value.To address this,a knowledge mapping was generated based on published studies to investigate the characteristics of bibliometric studies on acupuncture and the extent of duplicate publications,with the overarching goal of providing a comprehensive overview of the knowledge structure in this field.Methods:This cross-sectional study used three databases(PubMed,Web of Science,and Scopus)to identify relevant studies up to May 1,2024.In addition,the reference lists were retrieved as a supplement.To track research trends,we employed Microsoft Excel and R software to extract,code,and analyze information.Study selection,data extraction,and validation were performed independently by at least two reviewers.The reporting quality of included studies was assessed using the Preliminary guideline for reporting bibliometric reviews of the biomedical literature(BIBLIO).Results:Among the 6,221 bibliometric reviews examined,113 relevant publications were identified,80 focusing on various diseases/conditions.The annual number of publications has gradually increased,with the output in the past four years being 3.52 times higher than that before 2020.China(106)and Chengdu University of Traditional Chinese Medicine(16)have the highest number of publications.The most prolific author is Fan-Rong Liang,with six articles.The first bibliometric study,by Hai-Yan Li,was published in 2010.Journal of Pain Research,with 36 articles,holds the most publications.The top three diseases:diseases of the nervous system;symptoms,signs,or clinical findings not elsewhere classified;and mental,behavioral,or neurodevelopmental disorders.There may be potential duplication in research on 13 diseases/conditions,notably stroke,migraine,pain/analgesia,cancer pain,shoulder pain,facial paralysis/bell’s palsy,chronic pain,and cognitive impairment.In BIBLIO,the most frequently missing items are issues/topics(item 2),quality assessment(item 11),and descriptive findings(item 13).Conclusion:This study demonstrates that acupuncture bibliometrics is actively utilized to identify dominant diseases/conditions,aiding scholars in understand the knowledge structure and main topics.Although the number of related studies is increasing,with an average of 25 studies annually,overlap in some areas highlights the need for adherence to reporting guidelines and careful topic selection to ensure truly valuable insights and knowledge contributions.The adherence to BIBLIO’s 20 proposed items across analyzed articles,highlighting important in reporting practices.
基金funded by Tianjin Key Medical Discipline(Specialty)Construction Project,China(Grant No.TJYXZDXK-011A)Tianjin Medical University Cancer Institute&Hospital Nursing Special Fund Project(H2304)。
文摘Objectives:This study aimed to classify young breast cancer patients into distinct ambivalence over emotional expression and to explore the factors influencingthe level of ambivalence over emotional expression.Methods:A total of 217 young breast cancer patients were enrolled from a tertiary Grade A oncology hospital in Tianjin,China,using the convenience sampling method.All participants completed the general questionnaire,Ambivalence over Emotion Expression Questionnaire(AEQ),and Family Adapt-Ability and Cohesion Evaluation Scales-Chinese Version(FACES-CV).We employed exploratory latent profileanalysis for ambivalence over emotional expression profilingand logistic regression analysis to identify the influentialfactors Results:The results of the latent profileanalysis supported the models of four latent profiles,which were definedas“low conflict-lowexpression reflection”(19.2%),“high conflict-high inhibition expression”(43.9%),“moderate conflict-highregret expression”(18.1%),and“moderate conflict-desire understand”(18.8%).Logistic regression revealed that family cohesion,marital status,residence,per capita monthly income,and cancer stage were the influencingfactors of ambivalence over emotional expression in young breast cancer patients(P<0.05)Conclusions:Levels of ambivalence over emotional expression ameast cancer patients with breast cancer were highly heterogeneous.Medical staff should provide psychological counseling and health education tailored to the unique characteristics of emotional expression ambivalence in different patient groups to promote healthy emotional expression among patients.
基金supported by the National Natural Science Foundation of China(22379165,U21A20284)Natural Science Foundation of Hunan Province(2023JJ40704).
文摘Hard carbon(HC)is considered the most promising anode material for sodium-ion batteries(SIBs)due to its high costeffectiveness and outstanding overall performance.However,the amorphous and intricate microstructure of HC poses significant challenges in elucidating the structure-performance relationship,which has led to persistent misinterpretations regarding the intrinsic characteristics of closed pores.An irrational construction methodology of closed pores inevitably results in diminished plateau capacity,which severely restricts the practical application of HC in high-energy-density scenarios.This review provides a systematic exposition of the conceptual framework and origination mechanisms of closed pores,offering critical insights into their structural characteristics and formation pathways.Subsequently,by correlating lattice parameters with defect configurations,the structure-performance relationships governing desolvation kinetics and sodium storage behavior are rigorously established.Furthermore,pioneering advancements in structural engineering are critically synthesized to establish fundamental design principles for the rational modulation of closed pores in HC.It is imperative to emphasize that adopting a molecular-level perspective,coupled with a synergistic kinetic/thermodynamic approach,is critical for understanding and controlling the transformation process from open pores to closed pores.These innovative perspectives are strategically designed to accelerate the commercialization of HC,thereby catalyzing the sustainable and high-efficiency development of SIBs.
文摘Objective:This study aimed to examine the association between parent-child relationships and physically aggressive behavior among adolescents.Methods:This is a cross-sectional study that uses secondary data from the 2015 Indonesia Global School-Based Health Survey(IGSHS).Health surveys were conducted in 75 schools representing three regions(Sumatra,Java-Bali;Outer Sumatra;and Java-Bali)in 26 provinces and 68 districts/cities in Indonesia(N=10,139 students).Students who participated were aged 12-19 years,were enrolled in public schools in the junior and high school levels.Results:It has been seen that for most middle-aged adolescents(58.7%),their parents(25%-29%)pay less attention to academic assignments(homework),problems,and use of free time.The most significant factors that influence adolescents to commit violence are smoking and consuming alcohol.Adolescents who smoke are twice as likely to commit physical violence compared with adolescents who do not smoke(OR=2.005;95%CI=1.7062-2.396).Meanwhile,adolescents who consume alcohol are 1.8 times more likely to commit physical violence compared with adolescents who do not consume alcohol(OR=1.807;95%CI=1.421-2.298).Conclusions:Through educational activities and consultations,this study’s findings are valuable for establishing parenting programs among those concerned about their children’s aggressive behavior.Meanwhile,counseling programs can be started in schools by conducting self-detection of negative adolescent behavior,such as screening for smoking,alcohol consumption,sleep issues,and attempted suicide.
基金supported in part by the National Natural Science Foundation of China(NSFC)(Grant No.62001322)in part by the National Key Research and Development Program(Grant No.2020YFB2008800).
文摘In conventional piezoelectric micromachined ultrasonic transducers(PMUTs),the backside acoustic energy is often used inefficiently,resulting in up to half of the energy being wasted.Vacuum encapsulation can improve the energy utilization efficiency,but this technique is not compatible with state-of-the-art devices such as cantilever-based PMUTs.A closed back cavity provides an alternative method for effectively utilizing the backside acoustic energy.This paper investigates the effects of a closed back cavity on PMUT performance through theoretical analysis,simulations,and experimental verification.Increasing the cavity depth produces a periodic modulation of several key PMUT metrics,such as the relative frequency deviation and quality factor.The optimal cavity depth for PMUTs that ensures a robust resonant frequency and high quality factor is defined as a function of the acoustic wavelength.A closed back cavity also provides an effective method for continuously tuning the quality factor,and thus the bandwidth,of PMUTs.This work paves the way for air-coupled PMUTs with adjustable performance for various applications.
基金funded by the National Natural Science Foundation of China (Grant Nos.42230712,42472357)the China Postdoctoral Science Foundation (Grant No.2023MD734211).
文摘Loess is susceptible to loading effects such as significant changes in strength and volume variation caused by loading and wetting.In this study,considering the different connection states of pore water and gas in loess fabric,the gas phase closure case is incorporated into a unified form of the generalized effective stress framework,introducing a damage parameter considering the effects of closed pore gas.The loading effects of unsaturated loess under wide variations in saturation are described in a unified way,and the model performance is verified by corresponding stress and hydraulic path tests.The results indicated that the collapse response involves the initial void ratio of loess,and the coupled outwards motion of the loading-collapse(LC)yield surface under loading enhances its structural strength.Suction-enhanced yield stress requires a greater"tensile stress"to counteract its structural stability.The nucleation of bubbles at high saturation causes a decrease in yield stress.The loading effect exhibits a smaller collapse behavior when the influence of closed gas is considered,whereas the suction path does not cross the LC in the stress space under hydraulic action for the same parameters,which amplifies the influence of closed gas on loess deformation.
基金supported by the National Natural Science Foundation of China(T2341019)NSFC-Guangdong Joint Fund(U1132001)+9 种基金General Program of the National Natural Science Foundation of China(82174243 and 82204948)Natural Science Foundation of Guangdong Province,China(2023A1515110757)Guangzhou Science and Technology Plan Project(2024B03J1343)Major Scientific and Technological Project of Guangzhou Municipal Health Commission(20252D003)Research Project of Traditional Chinese Medicine Bureau of Guangdong Province(20241208)General project of Beijing Natural Science Foundation(7242227)Fundamental Research Funds for the Central Universities(BZY-JMZY-2022-001 and 2023-JYB-JBZD-009)High-level Key Discipline of the National Administration of Traditional Chinese Medicine-Traditional Chinese Constitutional Medicine(zyyzdxk-2023251)Major Science and Technology Special Projects in Hubei Province(2023BCA005)the Chief Scientist Research Project of Hubei Shizhen Laboratory(HSL2024SX0002).
文摘Objective:To study the relationship between qi stagnation constitution and suboptimal health status(SHS)or lifestyle.Methods:From 2012 to 2013,we conducted a cross-sectional survey of 24159 Chinese individuals aged 12-80 years.The qi stagnation constitution was assessed using the Constitution in Chinese Medicine Questionnaire.Health status was evaluated through medical records and the Subhealth Measurement Scale V1.0(SHMS V1.0).Health-promoting lifestyles were measured using the Health-Promoting Lifestyle Profile Ⅱ(HPLP-Ⅱ).Results:Of the 24159 participants,16.1%and 15.2%were classified as“always”and“sometimes”having the qi stagnation constitution,respectively.Those classified as“rarely”having the qi stagnation constitution scored higher on both the HPLP-Ⅱ and SHMS V1.0.The participants classified as“always”having the qi stagnation constitution showed a significant association with SHS or disease compared to other imbalanced constitutions.Those in the“always”category were approximately 21 times more likely to be classified as having SHS(odds ratio[OR]:21.17,95%confidence interval[CI]:15.74-28.45),whereas those in the“sometimes”category were approximately six times more likely(OR:5.89,95%CI:5.04-6.90).Accordingly,the qi stagnation constitution score was significantly associated with the diagnosis of SHS,with an area under the curve of 0.77(P<.001).A score of 18.75 yielded the highest Youden Index(0.407),with a sensitivity of 60.5%and a specificity of 80.3%.Significant associations were observed between health-promoting lifestyles and qi stagnation constitution severity in an ordinal regression analysis(P<.001).Protective factors included stress management(OR:1.59),self-actualization(OR:1.57),and exercise(OR:1.36).In contrast,poorer interpersonal relationships(OR:0.79),greater health responsibilities(OR:0.86),and poorer nutrition(OR:0.91)were associated with increased severity.Conclusion:Modulating the qi stagnation constitution through lifestyle interventions may help prevent the progression of SHS to disease,which aligns with core preventive principles in traditional Chinese medicine.
基金supported by the National Key Research and Development Program of China(2022YFC2504303)Innovation Foundation of National Clinical Research Center for Orthopaedics,Sports Medicine&Rehabilitation(2021-NCRC-CXJJ-ZH-24)Medical Innovation and Transformation Incubation Project of Tongji Hospital(2022ZHFY10).
文摘Objective Close reduction and internal fixation have gained popularity for the treatment of pelvic fractures.However,the closed reduction of bilateral displaced posterior pelvic ring disruption is a great challenge even for the most experienced surgeon.In this study,we describe in detail a novel unlocking closed reduction technique(UCRT)frame that allows strong traction for bilateral posterior pelvic ring displacement and presents preliminary clinical outcomes.Methods We retrospectively reviewed 32 patients with bilateral displaced posterior pelvic ring disruptions(AO/OTA 61-C2 and C3)who were initially treated with this technique between July 2017 and July 2022.According to the AO/OTA clas-sification,there were 9 cases(28.12%)of 61-C2,and 23 cases(71.88%)of 61-C3.There were 11 males,21 females,with an average age of 38.1 years.The interval from injury to operation was 4-27 days,with a cut-off of 12.5 days(receiver operat-ing characteristic curve).Operative time,blood loss,and postoperative radiographic findings were recorded.The functional outcomes and complications were followed.Results A total of 30(93.8%)patients achieved successful closed reduction,whereas 2 required open reduction.The success-ful closed reduction rate was 95.5%(21/22)in patients whose injury-to-operation time was less than 12.5 days.The vertical displacement percent correction of the obviously displaced hemipelvis was 70.20%±16.79%on average.The average degree of pelvic deformity correction was 64.86%±17.71%.Thirty patients were followed up for at least 12 months(12-36 months),and no complications of nonunion or redisplacement were observed.The Matta-Tornetta scoring standard revealed that the excellent(25/30)and good(4/30)rate was 96.7%.The Majeed clinical efficacy score revealed that the overall excellent and good rate was 100%.One patient had INFIX-related infection,and 2 reported numbness in the lateral thigh.The numbness was improved after INFIX removal.Conclusions This study presents an updated technique for closed reduction using a UCRT frame for bilateral posterior pelvic ring disruption,which has been shown to be effective,as indicated by excellent surgical and functional outcomes.
基金funded by the National Key Research and Development Program of China(No.2024YFE0208100).
文摘The scroll expander,as the core component of the micro-compressed air energy storage and power generation system,directly affects the output efficiency of the system.Meanwhile,the scroll profile plays a central role in determining the output performance of the scroll expander.In this study,in order to investigate the output characteristics of a variable cross-section scroll expander,numerical simulation and experimental studies were con-ducted by using Computational Fluid Dynamics(CFD)methods and dynamic mesh techniques.The impact of critical parameters on the output performance of the scroll expander was analyzed through the utilization of the control variable method.It is found that increasing the inlet pressure and temperature within a certain range can improve the output power of the scroll expander.However,the increase in temperature and meshing clearance leads to a decline in the overall output performance of the scroll expander,leading to a decrease in volumetric efficiency by 8.43%and 12.79%,respectively.The experiments demonstrate that under equal inlet pressure conditions,increasing the inlet temperature elevates both the rotational speed and torque output of the scroll expander.Specifically,compared to operating at normal temperatures,the output torque increases by 21.8%under high-temperature conditions.However,the rate of speed and torque variation decreases as a consequence of enlarged meshing clearance,resulting in increased internal leakage and reduction in isentropic efficiency.
基金National Nonprofit Institute Research Grant for the Institute of Basic Theory for Chinese Medicine,China Academy of Chinese Medical Sciences:Mechanism of Regulating Phlegm-Dampness Constitution to Prevent Metabolic Diseases based on Gut Microbiota-host DNA Methylation(No.YZ-202151)。
文摘OBJECTIVE:To investigate the difference in gut microbiota between population with damp-heat constitution(DHC)and balanced constitution(BC).METHODS:A multi-centered cross-sectional casecontrol study was conducted,which included 249 participants with damp-heat constitution or balanced constitution.Baseline information of participants was collected,and stool samples were collected for gut microbiota analysis.Principal coordinate analysis,linear discriminant analysis effect size analysis,receiver operating characteristic,random forest model,and phylogenetic investigation of communities by reconstruction of unobserved states methods were used to reveal the relationship between gut microbiota and the damp-heat constitution.RESULTS:Compared to those in the BC group,the richness and diversity of the microbiota,specifically those of several short-chain fatty acid producing genera such as Barnesiella,Coprobacter,and Butyricimonas,were significantly decreased in the DHC group.Regarding biological functions,flavonoid biosynthesis,propanoate metabolism,and nucleotide sugar metabolism were suppressed,while arachidonic acid metabolism and glutathione metabolism were enriched in the DHC group.Finally,a classifier based on the microbiota was constructed to discriminate between the DHC and BC populations.CONCLUSION:The gut microbiota of the DHC population exhibits significantly reduced diversity and is closely related to inflammation,metabolic disorders,and liver steatosis,which is consistent with clinical observations,thus serving as a potential diagnostic tool for traditional Chinese medicine constitution discrimination.
基金supported by the National Natural Science Foundation of China (Grant Nos.52304227 and 52104133)Scientific and Technological Research Platform for Disaster Prevention and Control of Deep Coal Mining (Anhui University of Science and Technology) (Grant No.DPDCM2208).
文摘To investigate the effects of the maximum principal stress direction(θ)and cross-section shape on the failure characteristics of sandstone,true-triaxial compression experiments were conducted using cubic samples with rectangular,circular,and D-shaped holes.Asθincreases from 0°to 60°in the rectangular hole,the left failure location shifts from the left corner to the left sidewall,the left corner,and then the floor,while the right failure location shifts from the right corner to the right sidewall,right roof corner,and then the roof.Furthermore,the initial failure vertical stress first decreases and then increases.In comparison,the failure severity in the rectangular hole decreases for variousθvalues as 30°>45°>60°>0°.With increasingθ,the fractal dimension(D)of rock slices first increases and then decreases.For the rectangular and D-shaped holes,whenθ=0°,30°,and 90°,D for the rectangular hole is less than that of the D-shaped hole.Whenθ=45°and 60°,D for the rectangular hole is greater than that of the D-shaped hole.Theoretical analysis indicates that the stress concentration at the rectangular and D-shaped corners is greater than the other areas.The failure location rotates with the rotation ofθ,and the failure occurs on the side with a high concentration of compressive stress,while the side with the tensile and compressive stresses remains relatively stable.Therefore,the fundamental reason for the rotation of failure location is the rotation of stress concentration,and the external influencing factor is the rotation ofθ.
文摘In this article,we are concerned with the C^(2)estimates for the k-convex solutions of a class of degenerate k-Hessian equations on closed Hermitian manifolds,whose function in the right-hand side is relevant to the unknown function and its gradient.We will get C^(0)estimate by promoting others′results,and get the“HMW estimate”of this equation such that the conditions of using blow-up analysis are satisfied,and the gradient estimate and second-order estimate will be obtained.Such an estimate will be helpful to study the existence for the solution of the equation.
基金supported by the Key Research and DevelopmentPlan in Shanxi Province of China(No.201803D421045)the Natural Science Foundation of Shanxi Province(No.2021-0302-123104)。
文摘This study introduces a novel method for reconstructing the 3D model of aluminum foam using cross-sectional sequence images.Combining precision milling and image acquisition,high-qual-ity cross-sectional images are obtained.Pore structures are segmented by the U-shaped network(U-Net)neural network integrated with the Canny edge detection operator,ensuring accurate pore delineation and edge extraction.The trained U-Net achieves 98.55%accuracy.The 2D data are superimposed and processed into 3D point clouds,enabling reconstruction of the pore structure and aluminum skeleton.Analysis of pore 01 shows the cross-sectional area initially increases,and then decreases with milling depth,with a uniform point distribution of 40 per layer.The reconstructed model exhibits a porosity of 77.5%,with section overlap rates between the 2D pore segmentation and the reconstructed model exceeding 96%,confirming high fidelity.Equivalent sphere diameters decrease with size,averaging 1.95 mm.Compression simulations reveal that the stress-strain curve of the 3D reconstruction model of aluminum foam exhibits fluctuations,and the stresses in the reconstruction model concentrate on thin cell walls,leading to localized deformations.This method accurately restores the aluminum foam’s complex internal structure,improving reconstruction preci-sion and simulation reliability.The approach offers a cost-efficient,high-precision technique for optimizing material performance in engineering applications.
