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Taxonomic classification of 80 near-Earth asteroids
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作者 Fan Mo Bin Li +9 位作者 HaiBin Zhao Jian Chen Yan Jin MengHui Tang Igor Molotov A.M.Abdelaziz A.Takey S.K.Tealib Ahmed.Shokry JianYang Li 《Earth and Planetary Physics》 2026年第1期196-204,共9页
Near-Earth objects are important not only in studying the early formation of the Solar System,but also because they pose a serious hazard to humanity when they make close approaches to the Earth.Study of their physica... Near-Earth objects are important not only in studying the early formation of the Solar System,but also because they pose a serious hazard to humanity when they make close approaches to the Earth.Study of their physical properties can provide useful information on their origin,evolution,and hazard to human beings.However,it remains challenging to investigate small,newly discovered,near-Earth objects because of our limited observational window.This investigation seeks to determine the visible colors of near-Earth asteroids(NEAs),perform an initial taxonomic classification based on visible colors and analyze possible correlations between the distribution of taxonomic classification and asteroid size or orbital parameters.Observations were performed in the broadband BVRI Johnson−Cousins photometric system,applied to images from the Yaoan High Precision Telescope and the 1.88 m telescope at the Kottamia Astronomical Observatory.We present new photometric observations of 84 near-Earth asteroids,and classify 80 of them taxonomically,based on their photometric colors.We find that nearly half(46.3%)of the objects in our sample can be classified as S-complex,26.3%as C-complex,6%as D-complex,and 15.0%as X-complex;the remaining belong to the A-or V-types.Additionally,we identify three P-type NEAs in our sample,according to the Tholen scheme.The fractional abundances of the C/X-complex members with absolute magnitude H≥17.0 were more than twice as large as those with H<17.0.However,the fractions of C-and S-complex members with diameters≤1 km and>1 km are nearly equal,while X-complex members tend to have sub-kilometer diameters.In our sample,the C/D-complex objects are predominant among those with a Jovian Tisserand parameter of T_(J)<3.1.These bodies could have a cometary origin.C-and S-complex members account for a considerable proportion of the asteroids that are potentially hazardous. 展开更多
关键词 near-Earth asteroids optical telescope photometric observation taxonomic classification
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A Novel Unsupervised Structural Attack and Defense for Graph Classification
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作者 Yadong Wang Zhiwei Zhang +2 位作者 Pengpeng Qiao Ye Yuan Guoren Wang 《Computers, Materials & Continua》 2026年第1期1761-1782,共22页
Graph Neural Networks(GNNs)have proven highly effective for graph classification across diverse fields such as social networks,bioinformatics,and finance,due to their capability to learn complex graph structures.Howev... Graph Neural Networks(GNNs)have proven highly effective for graph classification across diverse fields such as social networks,bioinformatics,and finance,due to their capability to learn complex graph structures.However,despite their success,GNNs remain vulnerable to adversarial attacks that can significantly degrade their classification accuracy.Existing adversarial attack strategies primarily rely on label information to guide the attacks,which limits their applicability in scenarios where such information is scarce or unavailable.This paper introduces an innovative unsupervised attack method for graph classification,which operates without relying on label information,thereby enhancing its applicability in a broad range of scenarios.Specifically,our method first leverages a graph contrastive learning loss to learn high-quality graph embeddings by comparing different stochastic augmented views of the graphs.To effectively perturb the graphs,we then introduce an implicit estimator that measures the impact of various modifications on graph structures.The proposed strategy identifies and flips edges with the top-K highest scores,determined by the estimator,to maximize the degradation of the model’s performance.In addition,to defend against such attack,we propose a lightweight regularization-based defense mechanism that is specifically tailored to mitigate the structural perturbations introduced by our attack strategy.It enhances model robustness by enforcing embedding consistency and edge-level smoothness during training.We conduct experiments on six public TU graph classification datasets:NCI1,NCI109,Mutagenicity,ENZYMES,COLLAB,and DBLP_v1,to evaluate the effectiveness of our attack and defense strategies.Under an attack budget of 3,the maximum reduction in model accuracy reaches 6.67%on the Graph Convolutional Network(GCN)and 11.67%on the Graph Attention Network(GAT)across different datasets,indicating that our unsupervised method induces degradation comparable to state-of-the-art supervised attacks.Meanwhile,our defense achieves the highest accuracy recovery of 3.89%(GCN)and 5.00%(GAT),demonstrating improved robustness against structural perturbations. 展开更多
关键词 Graph classification graph neural networks adversarial attack
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Graph Attention Networks for Skin Lesion Classification with CNN-Driven Node Features
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作者 Ghadah Naif Alwakid Samabia Tehsin +3 位作者 Mamoona Humayun Asad Farooq Ibrahim Alrashdi Amjad Alsirhani 《Computers, Materials & Continua》 2026年第1期1964-1984,共21页
Skin diseases affect millions worldwide.Early detection is key to preventing disfigurement,lifelong disability,or death.Dermoscopic images acquired in primary-care settings show high intra-class visual similarity and ... Skin diseases affect millions worldwide.Early detection is key to preventing disfigurement,lifelong disability,or death.Dermoscopic images acquired in primary-care settings show high intra-class visual similarity and severe class imbalance,and occasional imaging artifacts can create ambiguity for state-of-the-art convolutional neural networks(CNNs).We frame skin lesion recognition as graph-based reasoning and,to ensure fair evaluation and avoid data leakage,adopt a strict lesion-level partitioning strategy.Each image is first over-segmented using SLIC(Simple Linear Iterative Clustering)to produce perceptually homogeneous superpixels.These superpixels form the nodes of a region-adjacency graph whose edges encode spatial continuity.Node attributes are 1280-dimensional embeddings extracted with a lightweight yet expressive EfficientNet-B0 backbone,providing strong representational power at modest computational cost.The resulting graphs are processed by a five-layer Graph Attention Network(GAT)that learns to weight inter-node relationships dynamically and aggregates multi-hop context before classifying lesions into seven classes with a log-softmax output.Extensive experiments on the DermaMNIST benchmark show the proposed pipeline achieves 88.35%accuracy and 98.04%AUC,outperforming contemporary CNNs,AutoML approaches,and alternative graph neural networks.An ablation study indicates EfficientNet-B0 produces superior node descriptors compared with ResNet-18 and DenseNet,and that roughly five GAT layers strike a good balance between being too shallow and over-deep while avoiding oversmoothing.The method requires no data augmentation or external metadata,making it a drop-in upgrade for clinical computer-aided diagnosis systems. 展开更多
关键词 Graph neural network image classification DermaMNIST dataset graph representation
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Deep Learning for Brain Tumor Segmentation and Classification: A Systematic Review of Methods and Trends
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作者 Ameer Hamza Robertas Damaševicius 《Computers, Materials & Continua》 2026年第1期132-172,共41页
This systematic review aims to comprehensively examine and compare deep learning methods for brain tumor segmentation and classification using MRI and other imaging modalities,focusing on recent trends from 2022 to 20... This systematic review aims to comprehensively examine and compare deep learning methods for brain tumor segmentation and classification using MRI and other imaging modalities,focusing on recent trends from 2022 to 2025.The primary objective is to evaluate methodological advancements,model performance,dataset usage,and existing challenges in developing clinically robust AI systems.We included peer-reviewed journal articles and highimpact conference papers published between 2022 and 2025,written in English,that proposed or evaluated deep learning methods for brain tumor segmentation and/or classification.Excluded were non-open-access publications,books,and non-English articles.A structured search was conducted across Scopus,Google Scholar,Wiley,and Taylor&Francis,with the last search performed in August 2025.Risk of bias was not formally quantified but considered during full-text screening based on dataset diversity,validation methods,and availability of performance metrics.We used narrative synthesis and tabular benchmarking to compare performance metrics(e.g.,accuracy,Dice score)across model types(CNN,Transformer,Hybrid),imaging modalities,and datasets.A total of 49 studies were included(43 journal articles and 6 conference papers).These studies spanned over 9 public datasets(e.g.,BraTS,Figshare,REMBRANDT,MOLAB)and utilized a range of imaging modalities,predominantly MRI.Hybrid models,especially ResViT and UNetFormer,consistently achieved high performance,with classification accuracy exceeding 98%and segmentation Dice scores above 0.90 across multiple studies.Transformers and hybrid architectures showed increasing adoption post2023.Many studies lacked external validation and were evaluated only on a few benchmark datasets,raising concerns about generalizability and dataset bias.Few studies addressed clinical interpretability or uncertainty quantification.Despite promising results,particularly for hybrid deep learning models,widespread clinical adoption remains limited due to lack of validation,interpretability concerns,and real-world deployment barriers. 展开更多
关键词 Brain tumor segmentation brain tumor classification deep learning vision transformers hybrid models
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HCL Net: Deep Learning for Accurate Classification of Honeycombing Lung and Ground Glass Opacity in CT Images
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作者 Hairul Aysa Abdul Halim Sithiq Liyana Shuib +1 位作者 Muneer Ahmad Chermaine Deepa Antony 《Computers, Materials & Continua》 2026年第1期999-1023,共25页
Honeycombing Lung(HCL)is a chronic lung condition marked by advanced fibrosis,resulting in enlarged air spaces with thick fibrotic walls,which are visible on Computed Tomography(CT)scans.Differentiating between normal... Honeycombing Lung(HCL)is a chronic lung condition marked by advanced fibrosis,resulting in enlarged air spaces with thick fibrotic walls,which are visible on Computed Tomography(CT)scans.Differentiating between normal lung tissue,honeycombing lungs,and Ground Glass Opacity(GGO)in CT images is often challenging for radiologists and may lead to misinterpretations.Although earlier studies have proposed models to detect and classify HCL,many faced limitations such as high computational demands,lower accuracy,and difficulty distinguishing between HCL and GGO.CT images are highly effective for lung classification due to their high resolution,3D visualization,and sensitivity to tissue density variations.This study introduces Honeycombing Lungs Network(HCL Net),a novel classification algorithm inspired by ResNet50V2 and enhanced to overcome the shortcomings of previous approaches.HCL Net incorporates additional residual blocks,refined preprocessing techniques,and selective parameter tuning to improve classification performance.The dataset,sourced from the University Malaya Medical Centre(UMMC)and verified by expert radiologists,consists of CT images of normal,honeycombing,and GGO lungs.Experimental evaluations across five assessments demonstrated that HCL Net achieved an outstanding classification accuracy of approximately 99.97%.It also recorded strong performance in other metrics,achieving 93%precision,100%sensitivity,89%specificity,and an AUC-ROC score of 97%.Comparative analysis with baseline feature engineering methods confirmed the superior efficacy of HCL Net.The model significantly reduces misclassification,particularly between honeycombing and GGO lungs,enhancing diagnostic precision and reliability in lung image analysis. 展开更多
关键词 Deep learning honeycombing lung ground glass opacity Resnet50v2 multiclass classification
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An Improved Forest Fire Detection Model Using Audio Classification and Machine Learning
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作者 Kemahyanto Exaudi Deris Stiawan +4 位作者 Bhakti Yudho Suprapto Hanif Fakhrurroja MohdYazid Idris Tami AAlghamdi Rahmat Budiarto 《Computers, Materials & Continua》 2026年第1期2062-2085,共24页
Sudden wildfires cause significant global ecological damage.While satellite imagery has advanced early fire detection and mitigation,image-based systems face limitations including high false alarm rates,visual obstruc... Sudden wildfires cause significant global ecological damage.While satellite imagery has advanced early fire detection and mitigation,image-based systems face limitations including high false alarm rates,visual obstructions,and substantial computational demands,especially in complex forest terrains.To address these challenges,this study proposes a novel forest fire detection model utilizing audio classification and machine learning.We developed an audio-based pipeline using real-world environmental sound recordings.Sounds were converted into Mel-spectrograms and classified via a Convolutional Neural Network(CNN),enabling the capture of distinctive fire acoustic signatures(e.g.,crackling,roaring)that are minimally impacted by visual or weather conditions.Internet of Things(IoT)sound sensors were crucial for generating complex environmental parameters to optimize feature extraction.The CNN model achieved high performance in stratified 5-fold cross-validation(92.4%±1.6 accuracy,91.2%±1.8 F1-score)and on test data(94.93%accuracy,93.04%F1-score),with 98.44%precision and 88.32%recall,demonstrating reliability across environmental conditions.These results indicate that the audio-based approach not only improves detection reliability but also markedly reduces computational overhead compared to traditional image-based methods.The findings suggest that acoustic sensing integrated with machine learning offers a powerful,low-cost,and efficient solution for real-time forest fire monitoring in complex,dynamic environments. 展开更多
关键词 Audio classification convolutional neural network(CNN) environmental science forest fire detection machine learning spectrogram analysis IOT
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A Hybrid Deep Learning Multi-Class Classification Model for Alzheimer’s Disease Using Enhanced MRI Images
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作者 Ghadah Naif Alwakid 《Computers, Materials & Continua》 2026年第1期797-821,共25页
Alzheimer’s Disease(AD)is a progressive neurodegenerative disorder that significantly affects cognitive function,making early and accurate diagnosis essential.Traditional Deep Learning(DL)-based approaches often stru... Alzheimer’s Disease(AD)is a progressive neurodegenerative disorder that significantly affects cognitive function,making early and accurate diagnosis essential.Traditional Deep Learning(DL)-based approaches often struggle with low-contrast MRI images,class imbalance,and suboptimal feature extraction.This paper develops a Hybrid DL system that unites MobileNetV2 with adaptive classification methods to boost Alzheimer’s diagnosis by processing MRI scans.Image enhancement is done using Contrast-Limited Adaptive Histogram Equalization(CLAHE)and Enhanced Super-Resolution Generative Adversarial Networks(ESRGAN).A classification robustness enhancement system integrates class weighting techniques and a Matthews Correlation Coefficient(MCC)-based evaluation method into the design.The trained and validated model gives a 98.88%accuracy rate and 0.9614 MCC score.We also performed a 10-fold cross-validation experiment with an average accuracy of 96.52%(±1.51),a loss of 0.1671,and an MCC score of 0.9429 across folds.The proposed framework outperforms the state-of-the-art models with a 98%weighted F1-score while decreasing misdiagnosis results for every AD stage.The model demonstrates apparent separation abilities between AD progression stages according to the results of the confusion matrix analysis.These results validate the effectiveness of hybrid DL models with adaptive preprocessing for early and reliable Alzheimer’s diagnosis,contributing to improved computer-aided diagnosis(CAD)systems in clinical practice. 展开更多
关键词 Alzheimer’s disease deep learning MRI images MobileNetV2 contrast-limited adaptive histogram equalization(CLAHE) enhanced super-resolution generative adversarial networks(ESRGAN) multi-class classification
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CCDC40基因新发突变导致男性不育临床分析(附1例家系报告)
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作者 陈亮 王玲 +6 位作者 杨志芳 王国霖 吴德宇 杨宇卓 陈菲 徐阳 薛晴 《中国性科学》 2025年第4期1-5,共5页
目的探讨CCDC40基因新发位点突变导致的男性不育的临床特点。方法通过精液分析、电镜超微形态学分析、基因点突变检测等技术进行分析。结果精液分析结果提示精子活动力差、精子尾部发育不全,电镜超微形态学分析显示头部及尾部畸形、精... 目的探讨CCDC40基因新发位点突变导致的男性不育的临床特点。方法通过精液分析、电镜超微形态学分析、基因点突变检测等技术进行分析。结果精液分析结果提示精子活动力差、精子尾部发育不全,电镜超微形态学分析显示头部及尾部畸形、精核发育不良、轴丝微管数量减少/缺失、排列紊乱等。全外显子测序发现CCDC40基因c.3009_3040dup致病性纯合移码变异。结论CCDC40基因c.3009_3040dup纯合移码突变改变了蛋白序列,导致超微结构缺陷及精子尾部畸形;该突变为首次被鉴定,丰富了基因突变谱,为临床诊疗提供了借鉴。 展开更多
关键词 ccdc40 基因突变 男性不育
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瓦雷兹芽孢杆菌FZB42中DUF1453家族蛋白CcdC的生物信息学分析及对菌株生长发育的影响
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作者 李美橘 沈紫竹 +2 位作者 官陈郧 樊奔 赵银娟 《南京林业大学学报(自然科学版)》 北大核心 2025年第6期247-254,共8页
【目的】瓦雷兹芽孢杆菌(Bacillus velezensis)FZB42中的未知蛋白CcdC含有一个未知结构和功能的DUF1453结构域。利用生物信息学方法预测CcdC的生物学特性,并通过构建ccdC敲除株,研究CcdC蛋白的功能,为揭示DUF1453的结构和功能提供基础... 【目的】瓦雷兹芽孢杆菌(Bacillus velezensis)FZB42中的未知蛋白CcdC含有一个未知结构和功能的DUF1453结构域。利用生物信息学方法预测CcdC的生物学特性,并通过构建ccdC敲除株,研究CcdC蛋白的功能,为揭示DUF1453的结构和功能提供基础。【方法】利用生物信息学在线软件预测CcdC蛋白质的氨基酸组成及理化性质、疏水性、跨膜区、亚细胞定位等,并对不同细菌中的CcdC蛋白进行系统进化树分析。构建瓦雷兹芽孢杆菌FZB42的ccdC敲除株,比较野生型FZB42与ccdC敲除株在LB液体及固体培养基上的生长情况和DSM培养基中的芽孢形成情况。【结果】CcdC蛋白由160个氨基酸组成,它是一个位于细胞膜上且无信号肽的碱性、稳定、疏水的跨膜蛋白,存在3个丝氨酸磷酸化位点,其中第7位最有可能发生磷酸化。二级结构分析显示,CcdC蛋白主要以α-螺旋为主;三级结构分析显示,现有数据库中不存在与CcdC结构相似的蛋白质。通过菌落PCR,确定ccdC敲除株构建成功。比较FZB42与ccdC敲除株在生长和芽孢形成上的差异,发现ccdC基因的缺失影响了细菌生长和芽孢形成。【结论】生物信息学分析初步确定CcdC是一个膜蛋白,磷酸化位点的预测表明其可能参与信号传递功能,相互作用网络推测CcdC蛋白可能与生长发育有关。通过构建敲除菌株,明确了ccdC基因的缺失会影响细菌的生长发育,为后续探究DUF1453结构域的生物学功能和CcdC对瓦雷兹芽孢杆菌FZB42的生长发育调控奠定了基础。 展开更多
关键词 DUF1453结构域 ccdc蛋白 生物信息学 生长发育 瓦雷兹芽孢杆菌
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CCDC97影响肝癌的免疫微环境以及生物学功能 被引量:1
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作者 莫灵玲 吴新悦 +1 位作者 彭小花 陈闯 《细胞与分子免疫学杂志》 北大核心 2025年第1期23-30,共8页
目的探讨CCDC97与肝细胞癌(HCC)的临床及免疫价值。方法从癌症基因组图谱(TCGA)和国际癌症基因组联盟(ICGC)数据库中获取HCC患者的临床和RNA测序数据。通过生物信息学和数据库分析,研究CCDC97在HCC中的作用,并利用体外实验探讨其功能。... 目的探讨CCDC97与肝细胞癌(HCC)的临床及免疫价值。方法从癌症基因组图谱(TCGA)和国际癌症基因组联盟(ICGC)数据库中获取HCC患者的临床和RNA测序数据。通过生物信息学和数据库分析,研究CCDC97在HCC中的作用,并利用体外实验探讨其功能。结果HCC患者和肝癌细胞中CCDC97的表达水平高,并与病理特征、预后等密切相关。CCDC97被确认是一个新的预后因素。CCDC97与剪接体通路相关,该通路在肿瘤中高度活跃,可能促进癌变。CCDC97在多种免疫细胞中高表达,与免疫微环境有关。此外,敲低CCDC97在体外实验中抑制了细胞的侵袭、迁移和增殖。结论CCDC97在HCC进展以及免疫微环境中发挥重要作用,可能成为HCC预后和治疗的新靶点。 展开更多
关键词 肝细胞癌(HCC) ccdc97 免疫微环境 剪接体 免疫浸润
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Urban tree species classification based on multispectral airborne LiDAR 被引量:1
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作者 HU Pei-Lun CHEN Yu-Wei +3 位作者 Mohammad Imangholiloo Markus Holopainen WANG Yi-Cheng Juha Hyyppä 《红外与毫米波学报》 北大核心 2025年第2期211-216,共6页
Urban tree species provide various essential ecosystem services in cities,such as regulating urban temperatures,reducing noise,capturing carbon,and mitigating the urban heat island effect.The quality of these services... Urban tree species provide various essential ecosystem services in cities,such as regulating urban temperatures,reducing noise,capturing carbon,and mitigating the urban heat island effect.The quality of these services is influenced by species diversity,tree health,and the distribution and the composition of trees.Traditionally,data on urban trees has been collected through field surveys and manual interpretation of remote sensing images.In this study,we evaluated the effectiveness of multispectral airborne laser scanning(ALS)data in classifying 24 common urban roadside tree species in Espoo,Finland.Tree crown structure information,intensity features,and spectral data were used for classification.Eight different machine learning algorithms were tested,with the extra trees(ET)algorithm performing the best,achieving an overall accuracy of 71.7%using multispectral LiDAR data.This result highlights that integrating structural and spectral information within a single framework can improve the classification accuracy.Future research will focus on identifying the most important features for species classification and developing algorithms with greater efficiency and accuracy. 展开更多
关键词 multispectral airborne LiDAR machine learning tree species classification
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CCDC80在恶性肿瘤中的机制研究进展及临床意义
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作者 苏亚斯 石喆 戴文斌 《中国现代医生》 2025年第27期112-116,共5页
含卷曲螺旋结构域蛋白(coiled-coil domain containing,CCDC)80是一种可编码蛋白,在多种人体组织中广泛表达。研究发现CCDC80在多种关键生理过程中均发挥重要作用,且与恶性肿瘤密切相关,呈现抑癌或促癌的双向作用。因此,探究CCDC80在恶... 含卷曲螺旋结构域蛋白(coiled-coil domain containing,CCDC)80是一种可编码蛋白,在多种人体组织中广泛表达。研究发现CCDC80在多种关键生理过程中均发挥重要作用,且与恶性肿瘤密切相关,呈现抑癌或促癌的双向作用。因此,探究CCDC80在恶性肿瘤中的作用机制及临床意义,对攻克人类恶性肿瘤和研发相关靶向药物具有重要意义。本综述重点阐述CCDC80在恶性肿瘤中发挥各种生物学功能的分子机制和临床意义,以期为CCDC80介导肿瘤发生发展分子机制的深入研究和相关防治药物的研发提供新的思路和见解。 展开更多
关键词 含卷曲螺旋结构域蛋白80 ccdc80 恶性肿瘤 分子机制
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Impact of classification granularity on interdisciplinary performance assessment of research institutes and organizations 被引量:1
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作者 Jiandong Zhang Sonia Gruber Rainer Frietsch 《Journal of Data and Information Science》 2025年第2期61-79,共19页
Purpose:Interdisciplinary research has become a critical approach to addressing complex societal,economic,technological,and environmental challenges,driving innovation and integrating scientific knowledge.While interd... Purpose:Interdisciplinary research has become a critical approach to addressing complex societal,economic,technological,and environmental challenges,driving innovation and integrating scientific knowledge.While interdisciplinarity indicators are widely used to evaluate research performance,the impact of classification granularity on these assessments remains underexplored.Design/methodology/approach:This study investigates how different levels of classification granularity-macro,meso,and micro-affect the evaluation of interdisciplinarity in research institutes.Using a dataset of 262 institutes from four major German non-university organizations(FHG,HGF,MPG,WGL)from 2018 to 2022,we examine inconsistencies in interdisciplinarity across levels,analyze ranking changes,and explore the influence of institutional fields and research focus(applied vs.basic).Findings:Our findings reveal significant inconsistencies in interdisciplinarity across classification levels,with rankings varying substantially.Notably,the Fraunhofer Society(FHG),which performs well at the macro level,experiences significant ranking declines at meso and micro levels.Normalizing interdisciplinarity by research field confirmed that these declines persist.The research focus of institutes,whether applied,basic,or mixed,does not significantly explain the observed ranking dynamics.Research limitations:This study has only considered the publication-based dimension of institutional interdisciplinarity and has not explored other aspects.Practical implications:The findings provide insights for policymakers,research managers,and scholars to better interpret interdisciplinarity metrics and support interdisciplinary research effectively.Originality/value:This study underscores the critical role of classification granularity in interdisciplinarity assessment and emphasizes the need for standardized approaches to ensure robust and fair evaluations. 展开更多
关键词 Interdisciplinarity Paper-level classification system Organization evaluation
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lncRNA CCDC183-AS1调节miR-628-5p/KLF12信号轴对宫颈癌细胞恶性生物学行为的影响
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作者 王瑾 高倩 +1 位作者 刁丛 刘蓬 《中国优生与遗传杂志》 2025年第5期1040-1046,共7页
目的该研究旨在探讨长链非编码RNA(lncRNA)CCDC183-AS1调节miR-628-5p/KLF转录因子12(KLF12)信号通路对宫颈癌细胞恶性生物学行为的影响。方法对宫颈癌细胞(CaSki、HeLa、SiHa、MS751)进行表型筛选,选择CaSki细胞分为si-NC组、si-CCDC18... 目的该研究旨在探讨长链非编码RNA(lncRNA)CCDC183-AS1调节miR-628-5p/KLF转录因子12(KLF12)信号通路对宫颈癌细胞恶性生物学行为的影响。方法对宫颈癌细胞(CaSki、HeLa、SiHa、MS751)进行表型筛选,选择CaSki细胞分为si-NC组、si-CCDC183-AS1组、mimic NC组、miR-628-5p mimic组、si-CCDC183-AS1+inhibitor NC组、si-CCDC183-AS1+miR-628-5p inhibitor组。qRT-PCR检测lncRNA CCDC183-AS1、miR-628-5p、KLF12 mRNA表达水平;EdU检测CaSki细胞增殖;Transwell检测CaSki细胞迁移和侵袭情况;流式检测CaSki细胞凋亡率;Western blot检测KLF12蛋白表达;双荧光素酶检测lncRNA CCDC183-AS1与miR-628-5p、miR-628-5p与KLF12的相互关系。结果与人正常宫颈细胞相比,宫颈癌细胞(CaSki、HeLa、SiHa、MS751)miR-628-5p表达降低,CCDC183-AS1和KLF12 mRNA表达提高,CaSki细胞表型变化最明显(P<0.05);与si-NC组比较,si-CCDC183-AS1组CaSki中CCDC183-AS1和KLF12表达、细胞增殖、迁移和侵袭能力降低,miR-628-5p表达和凋亡率升高(P<0.05);与si-CCDC183-AS1+inhibitor NC组比较,si-CCDC183-AS1+miR-628-5p inhibitor组CaSki中KLF12表达、细胞增殖、迁移和侵袭能力提高,miR-628-5p表达和凋亡率降低(P<0.05);双荧光素酶检测显示,lncRNA CCDC183-AS1与miR-628-5p、miR-628-5p与KLF12存在靶向关系(P<0.05)。结论lncRNA CCDC183-AS1可能通过抑制miR-628-5p,促进KLF12表达,促进宫颈癌细胞恶性生物学行为。 展开更多
关键词 lncRNA ccdc183-AS1 miR-628-5p KLF12 宫颈癌细胞 恶性生物学行为
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YOLOCSP-PEST for Crops Pest Localization and Classification 被引量:1
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作者 Farooq Ali Huma Qayyum +2 位作者 Kashif Saleem Iftikhar Ahmad Muhammad Javed Iqbal 《Computers, Materials & Continua》 2025年第2期2373-2388,共16页
Preservation of the crops depends on early and accurate detection of pests on crops as they cause several diseases decreasing crop production and quality. Several deep-learning techniques have been applied to overcome... Preservation of the crops depends on early and accurate detection of pests on crops as they cause several diseases decreasing crop production and quality. Several deep-learning techniques have been applied to overcome the issue of pest detection on crops. We have developed the YOLOCSP-PEST model for Pest localization and classification. With the Cross Stage Partial Network (CSPNET) backbone, the proposed model is a modified version of You Only Look Once Version 7 (YOLOv7) that is intended primarily for pest localization and classification. Our proposed model gives exceptionally good results under conditions that are very challenging for any other comparable models especially conditions where we have issues with the luminance and the orientation of the images. It helps farmers working out on their crops in distant areas to determine any infestation quickly and accurately on their crops which helps in the quality and quantity of the production yield. The model has been trained and tested on 2 datasets namely the IP102 data set and a local crop data set on both of which it has shown exceptional results. It gave us a mean average precision (mAP) of 88.40% along with a precision of 85.55% and a recall of 84.25% on the IP102 dataset meanwhile giving a mAP of 97.18% on the local data set along with a recall of 94.88% and a precision of 97.50%. These findings demonstrate that the proposed model is very effective in detecting real-life scenarios and can help in the production of crops improving the yield quality and quantity at the same time. 展开更多
关键词 Deep learning classification of pests YOLOCSP-PEST pest detection
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Nondestructive detection and classification of impurities-containing seed cotton based on hyperspectral imaging and one-dimensional convolutional neural network 被引量:1
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作者 Yeqi Fei Zhenye Li +2 位作者 Tingting Zhu Zengtao Chen Chao Ni 《Digital Communications and Networks》 2025年第2期308-316,共9页
The cleanliness of seed cotton plays a critical role in the pre-treatment of cotton textiles,and the removal of impurity during the harvesting process directly determines the quality and market value of cotton textile... The cleanliness of seed cotton plays a critical role in the pre-treatment of cotton textiles,and the removal of impurity during the harvesting process directly determines the quality and market value of cotton textiles.By fusing band combination optimization with deep learning,this study aims to achieve more efficient and accurate detection of film impurities in seed cotton on the production line.By applying hyperspectral imaging and a one-dimensional deep learning algorithm,we detect and classify impurities in seed cotton after harvest.The main categories detected include pure cotton,conveyor belt,film covering seed cotton,and film adhered to the conveyor belt.The proposed method achieves an impurity detection rate of 99.698%.To further ensure the feasibility and practical application potential of this strategy,we compare our results against existing mainstream methods.In addition,the model shows excellent recognition performance on pseudo-color images of real samples.With a processing time of 11.764μs per pixel from experimental data,it shows a much improved speed requirement while maintaining the accuracy of real production lines.This strategy provides an accurate and efficient method for removing impurities during cotton processing. 展开更多
关键词 Seed cotton Film impurity Hyperspectral imaging Band optimization classification
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Multi-Scale Dilated Convolution Network for SPECT-MPI Cardiovascular Disease Classification with Adaptive Denoising and Attenuation Correction
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作者 A.Robert Singh Suganya Athisayamani +1 位作者 Gyanendra Prasad Joshi Bhanu Shrestha 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期299-327,共29页
Myocardial perfusion imaging(MPI),which uses single-photon emission computed tomography(SPECT),is a well-known estimating tool for medical diagnosis,employing the classification of images to show situations in coronar... Myocardial perfusion imaging(MPI),which uses single-photon emission computed tomography(SPECT),is a well-known estimating tool for medical diagnosis,employing the classification of images to show situations in coronary artery disease(CAD).The automatic classification of SPECT images for different techniques has achieved near-optimal accuracy when using convolutional neural networks(CNNs).This paper uses a SPECT classification framework with three steps:1)Image denoising,2)Attenuation correction,and 3)Image classification.Image denoising is done by a U-Net architecture that ensures effective image denoising.Attenuation correction is implemented by a convolution neural network model that can remove the attenuation that affects the feature extraction process of classification.Finally,a novel multi-scale diluted convolution(MSDC)network is proposed.It merges the features extracted in different scales and makes the model learn the features more efficiently.Three scales of filters with size 3×3 are used to extract features.All three steps are compared with state-of-the-art methods.The proposed denoising architecture ensures a high-quality image with the highest peak signal-to-noise ratio(PSNR)value of 39.7.The proposed classification method is compared with the five different CNN models,and the proposed method ensures better classification with an accuracy of 96%,precision of 87%,sensitivity of 87%,specificity of 89%,and F1-score of 87%.To demonstrate the importance of preprocessing,the classification model was analyzed without denoising and attenuation correction. 展开更多
关键词 SPECT-MPI CAD MSDC DENOISING attenuation correction classification
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Automated ECG arrhythmia classification using hybrid CNN-SVM architectures 被引量:1
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作者 Amine Ben Slama Yessine Amri +1 位作者 Ahmed Fnaiech Hanene Sahli 《Journal of Electronic Science and Technology》 2025年第3期43-55,共13页
Diagnosing cardiac diseases relies heavily on electrocardiogram(ECG)analysis,but detecting myocardial infarction-related arrhythmias remains challenging due to irregular heartbeats and signal variations.Despite advanc... Diagnosing cardiac diseases relies heavily on electrocardiogram(ECG)analysis,but detecting myocardial infarction-related arrhythmias remains challenging due to irregular heartbeats and signal variations.Despite advancements in machine learning,achieving both high accuracy and low computational cost for arrhythmia classification remains a critical issue.Computer-aided diagnosis systems can play a key role in early detection,reducing mortality rates associated with cardiac disorders.This study proposes a fully automated approach for ECG arrhythmia classification using deep learning and machine learning techniques to improve diagnostic accuracy while minimizing processing time.The methodology consists of three stages:1)preprocessing,where ECG signals undergo noise reduction and feature extraction;2)feature Identification,where deep convolutional neural network(CNN)blocks,combined with data augmentation and transfer learning,extract key parameters;3)classification,where a hybrid CNN-SVM model is employed for arrhythmia recognition.CNN-extracted features were fed into a binary support vector machine(SVM)classifier,and model performance was assessed using five-fold cross-validation.Experimental findings demonstrated that the CNN2 model achieved 85.52%accuracy,while the hybrid CNN2-SVM approach significantly improved accuracy to 97.33%,outperforming conventional methods.This model enhances classification efficiency while reducing computational complexity.The proposed approach bridges the gap between accuracy and processing speed in ECG arrhythmia classification,offering a promising solution for real-time clinical applications.Its superior performance compared to nonlinear classifiers highlights its potential for improving automated cardiac diagnosis. 展开更多
关键词 ARRHYTHMIA classification Convolutional neural networks ECG signals Support vector machine
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Various classification methods for diabetes mellitus in the management of blood glucose control 被引量:1
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作者 Qing Jiang Yun Hu Jian-Hua Ma 《World Journal of Diabetes》 2025年第5期1-7,共7页
In the era of precision medicine,the classification of diabetes mellitus has evolved beyond the traditional categories.Various classification methods now account for a multitude of factors,including variations in spec... In the era of precision medicine,the classification of diabetes mellitus has evolved beyond the traditional categories.Various classification methods now account for a multitude of factors,including variations in specific genes,type ofβ-cell impairment,degree of insulin resistance,and clinical characteristics of metabolic profiles.Improved classification methods enable healthcare providers to formulate blood glucose management strategies more precisely.Applying these updated classification systems,will assist clinicians in further optimising treatment plans,including targeted drug therapies,personalized dietary advice,and specific exercise plans.Ultimately,this will facilitate stricter blood glucose control,minimize the risks of hypoglycaemia and hyperglycaemia,and reduce long-term complications associated with diabetes. 展开更多
关键词 Diabetes classification Glycaemic control Personalised treatment Soft clustering Precision medicine
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Classification and provenance of exotic impact glasses in Chang’e-5 lunar soil 被引量:1
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作者 YunHong Fan BiWen Wang +3 位作者 Wei Yang QiuLi Li HuiJuan Zhang ShiTou Wu 《Earth and Planetary Physics》 2025年第6期1099-1112,共14页
Lunar impact glasses have been identified as crucial indicators of geochemical information regarding their source regions. Impact glasses can be categorized as either local or exotic. Those preserving geochemical sign... Lunar impact glasses have been identified as crucial indicators of geochemical information regarding their source regions. Impact glasses can be categorized as either local or exotic. Those preserving geochemical signatures matching local lithologies (e.g., mare basalts or their single minerals) or regolith bulk soil compositions are classified as “local”. Otherwise, they could be defined as “exotic”. The analysis of exotic glasses provides the opportunity to explore previously unsampled lunar areas. This study focuses on the identification of exotic glasses within the Chang’e-5 (CE-5) soil sample by analyzing the trace elements of 28 impact glasses with distinct major element compositions in comparison with the CE-5 bulk soil. However, the results indicate that 18 of the analyzed glasses exhibit trace element compositions comparable to those of the local CE-5 materials. In particular, some of them could match the local single mineral component in major and trace elements, suggesting a local origin. Therefore, it is recommended that the investigation be expanded from using major elements to including nonvolatile trace elements, with a view to enhancing our understanding on the provenance of lunar impact glasses. To achieve a more accurate identification of exotic glasses within the CE-5 soil sample, a novel classification plot of Mg# versus La is proposed. The remaining 10 glasses, which exhibit diverse trace element variations, were identified as exotic. A comparative analysis of their chemical characteristics with remote sensing data indicates that they may have originated from the Aristarchus, Mairan, Sharp, or Pythagoras craters. This study elucidates the classification and possible provenance of exotic materials within the CE-5 soil sample, thereby providing constraints for the enhanced identification of local and exotic components at the CE-5 landing site. 展开更多
关键词 Chang’e-5 impact glass exotic materials classification PROVENANCE
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