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Multi-Scale Dilated Convolution Network for SPECT-MPI Cardiovascular Disease Classification with Adaptive Denoising and Attenuation Correction
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作者 A.Robert Singh Suganya Athisayamani +1 位作者 Gyanendra Prasad Joshi Bhanu Shrestha 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期299-327,共29页
Myocardial perfusion imaging(MPI),which uses single-photon emission computed tomography(SPECT),is a well-known estimating tool for medical diagnosis,employing the classification of images to show situations in coronar... Myocardial perfusion imaging(MPI),which uses single-photon emission computed tomography(SPECT),is a well-known estimating tool for medical diagnosis,employing the classification of images to show situations in coronary artery disease(CAD).The automatic classification of SPECT images for different techniques has achieved near-optimal accuracy when using convolutional neural networks(CNNs).This paper uses a SPECT classification framework with three steps:1)Image denoising,2)Attenuation correction,and 3)Image classification.Image denoising is done by a U-Net architecture that ensures effective image denoising.Attenuation correction is implemented by a convolution neural network model that can remove the attenuation that affects the feature extraction process of classification.Finally,a novel multi-scale diluted convolution(MSDC)network is proposed.It merges the features extracted in different scales and makes the model learn the features more efficiently.Three scales of filters with size 3×3 are used to extract features.All three steps are compared with state-of-the-art methods.The proposed denoising architecture ensures a high-quality image with the highest peak signal-to-noise ratio(PSNR)value of 39.7.The proposed classification method is compared with the five different CNN models,and the proposed method ensures better classification with an accuracy of 96%,precision of 87%,sensitivity of 87%,specificity of 89%,and F1-score of 87%.To demonstrate the importance of preprocessing,the classification model was analyzed without denoising and attenuation correction. 展开更多
关键词 SPECT-MPI CAD MSDC DENOISING attenuation correction classification
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Multi-Label Machine Learning Classification of Cardiovascular Diseases
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作者 Chih-Ta Yen Jung-Ren Wong Chia-Hsang Chang 《Computers, Materials & Continua》 2025年第7期347-363,共17页
In its 2023 global health statistics,the World Health Organization noted that noncommunicable diseases(NCDs)remain the leading cause of disease burden worldwide,with cardiovascular diseases(CVDs)resulting in more deat... In its 2023 global health statistics,the World Health Organization noted that noncommunicable diseases(NCDs)remain the leading cause of disease burden worldwide,with cardiovascular diseases(CVDs)resulting in more deaths than the three other major NCDs combined.In this study,we developed a method that can comprehensively detect which CVDs are present in a patient.Specifically,we propose a multi-label classification method that utilizes photoplethysmography(PPG)signals and physiological characteristics from public datasets to classify four types of CVDs and related conditions:hypertension,diabetes,cerebral infarction,and cerebrovascular disease.Our approach to multi-disease classification of cardiovascular diseases(CVDs)using PPG signals achieves the highest classification performance when encompassing the broadest range of disease categories,thereby offering a more comprehensive assessment of human health.We employ a multi-label classification strategy to simultaneously predict the presence or absence of multiple diseases.Specifically,we first apply the Savitzky-Golay(S-G)filter to the PPG signals to reduce noise and then transform into statistical features.We integrate processed PPG signals with individual physiological features as a multimodal input,thereby expanding the learned feature space.Notably,even with a simple machine learning method,this approach can achieve relatively high accuracy.The proposed method achieved a maximum F1-score of 0.91,minimum Hamming loss of 0.04,and an accuracy of 0.95.Thus,our method represents an effective and rapid solution for detecting multiple diseases simultaneously,which is beneficial for comprehensively managing CVDs. 展开更多
关键词 PHOTOPLETHYSMOGRAPHY machine learning health management multi-label classification cardiovascu-lar disease
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基于NLRP3/ASC/Caspase-1途径探讨清热散浊饮对痛风性关节炎合并高尿酸血症模型大鼠的作用机制 被引量:2
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作者 李浩林 柏倩 +5 位作者 程伟刚 李伟青 杨娟娟 贺佩鑫 杨会军 王海东 《中国实验方剂学杂志》 北大核心 2025年第3期49-57,共9页
目的:探讨清热散浊饮治疗痛风性关节炎(GA)合并高尿酸血症(HUA)的效果及相关作用机制。方法:将60只雄性SD大鼠随机分为正常组、模型组、秋水仙碱组(0.5 mg·kg^(-1))、清热散浊饮低、中、高剂量组(17、34、68 g·kg^(-1)),每组1... 目的:探讨清热散浊饮治疗痛风性关节炎(GA)合并高尿酸血症(HUA)的效果及相关作用机制。方法:将60只雄性SD大鼠随机分为正常组、模型组、秋水仙碱组(0.5 mg·kg^(-1))、清热散浊饮低、中、高剂量组(17、34、68 g·kg^(-1)),每组10只,除正常组外,其余大鼠均使用改良后GA合并HUA的造模方法;同时给药组每日下午灌胃相应药物,正常组和模型组灌胃等体积无菌生理盐水。末次给药2 h后测定大鼠血清尿酸(SUA)浓度,计算大鼠造模后0.5、12、24、48 h踝关节肿胀程度并对关节炎症评分,苏木素-伊红(HE)染色观察大鼠踝关节病理组织形态,酶联免疫吸附测定法(ELISA)检测大鼠血清肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)、C反应蛋白(CRP)、白细胞介素-18(IL-18)含量,实时荧光定量聚合酶链式反应(Real-time PCR)检测各组大鼠踝关节滑膜组织中NOD样受体蛋白3(NLRP3)、凋亡相关斑点样蛋白(ASC)、胱天蛋白酶-1(Caspase-1)、焦孔素D(GSDMD)、核转录因子-κB(NF-κB)mRNA表达水平,蛋白免疫印迹法(Western blot)检测大鼠滑膜组织中NLRP3、ASC、Caspase-1蛋白表达,免疫组化检测关节滑膜组织中GSDMD、NF-κB蛋白表达。结果:与正常组比较,模型组大鼠SUA浓度明显升高(P<0.05),踝关节肿胀程度及关节炎症评分升高(P<0.05),滑膜内血管数量增多,滑膜囊内见炎细胞灶,血清TNF-α、IL-1β、CRP、IL-18含量明显升高(P<0.05),踝关节滑膜组织中NLRP3、ASC、Caspase-1、GSDMD、NF-κB mRNA及蛋白表达水平明显升高(P<0.05);与模型组比较,清热散浊饮中、高剂量组大鼠SUA浓度明显降低(P<0.05),踝关节肿胀程度减轻(P<0.05),关节炎症评分降低(P<0.05),血清TNF-α、IL-1β、CRP、IL-18含量降低(P<0.05),踝关节滑膜组织中NLRP3、ASC、Caspase-1、GSDMD、NF-κB mRNA水平及蛋白表达水平降低(P<0.05),但在改善踝关节病理组织形态方面,仅有高剂量组大鼠踝关节滑膜形态良好,关节软骨未见明显病变。结论:清热散浊饮可能通过下调NLRP3/ASC/Caspase-1通路活性,抑制TNF-α、IL-1β、CRP、IL-18等炎症因子表达,从而发挥防治GA合并HUA的作用。 展开更多
关键词 清热散浊饮 NOD样受体蛋白3(NLRP3)/凋亡相关斑点样蛋白(asc)/胱天蛋白酶-1(Caspase-1)通路 痛风性关节炎 高尿酸血症
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Comprehensive classifications for the endovascular recanalization of vertebral artery stump syndrome 被引量:2
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作者 Wenbin Zhang Chao Li +4 位作者 Mingchao Shi Jie Zhou Feixue Yue Kangjia Song Shouchun Wang 《Journal of Interventional Medicine》 2023年第2期81-89,共9页
Background:and purpose:To share our single-center vertebral artery stump syndrome(VASS)treatment experience and assess the role of comprehensive classification based on anatomic development,proximal conditions,and dis... Background:and purpose:To share our single-center vertebral artery stump syndrome(VASS)treatment experience and assess the role of comprehensive classification based on anatomic development,proximal conditions,and distal conditions(PAD).Materials and methods:Data were retrospectively collected from patients who underwent endovascular thrombectomy(EVT)at the Stroke Center of the First Hospital of Jilin University between January 2016 and December2021.Among patients with acute ischemic stroke in the posterior circulation,those with acute occlusion of the intracranial arteries and occlusion at the origin of the vertebral artery confirmed by digital subtraction angiography were selected.The clinical data were summarized and analyzed.Results:Fifteen patients with VASS were enrolled in the study.The overall success rate of surgical recanalization was 80%.The successful proximal recanalization rate was 70.6%,and the recanalization rates for P1,P2,P3,and P4 were 100%,71.4%,50%,and 66.67%,respectively.The mean operation times for the A1 and A2 types were124 and 120 min,respectively.The successful distal recanalization rate was 91.7%,and the recanalization rates for types D1,D2,D3,and D4 were 100%,83.3%,100%,and 100%,respectively.Five patients experienced perioperative complications(incidence rate:33.3%).Distal embolism occurred in three patients(incidence rate:20%).No dissection or subarachnoid hemorrhage occurred in any patient.Conclusion:EVT is a technically feasible treatment for VASS,and comprehensive PAD classification can,to a certain extent,help initially estimate the difficulty of surgery and provide guidance for interventional procedures. 展开更多
关键词 Vertebral artery stump syndrome Endovascular thrombectomy Angiographic classification RECANALIZATION Acute ischemic stroke
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异鼠李素调控NLRP3/ASC/caspase-1轴介导的细胞焦亡减轻急性肺损伤的机制研究 被引量:2
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作者 孙亚磊 郭宇 +5 位作者 王欣雨 张雅素 程雪 朱珂 陈立典 冯晓东 《中国中药杂志》 北大核心 2025年第15期4120-4128,共9页
旨在探讨异鼠李素(Isor)对急性肺损伤(ALI)的干预作用及对NOD样受体热蛋白结构域3(NLRP3)/凋亡相关斑点样蛋白(ASC)/半胱氨酸蛋白酶-1(caspase-1)轴介导的细胞焦亡机制的调控效应。在体内实验中,将60只BALB/c小鼠分为5组,除对照组外,其... 旨在探讨异鼠李素(Isor)对急性肺损伤(ALI)的干预作用及对NOD样受体热蛋白结构域3(NLRP3)/凋亡相关斑点样蛋白(ASC)/半胱氨酸蛋白酶-1(caspase-1)轴介导的细胞焦亡机制的调控效应。在体内实验中,将60只BALB/c小鼠分为5组,除对照组外,其他组小鼠灌胃给药1 h后气管滴注LPS造模,12 h后取材。体外实验中,RAW264.7细胞分为5组,除对照组外,其他组细胞药物预处理2 h后进行造模、指标检测。苏木素-伊红(HE)染色法观察肺组织的病理改变,同时检测肺肿胀程度、肺泡灌洗液(BALF)中蛋白水平、肺组织髓过氧化物酶(MPO)水平。细胞计数试剂8(CCK-8)方法进行细胞增殖毒性及细胞活力测定实验。酶联免疫吸附测定(ELISA)检测白细胞介素(IL)-1β、IL-6、IL-18、肿瘤坏死因子-α(TNF-α)水平,免疫组化、免疫荧光、免疫印迹等方法检测NLRP3、ASC、剪切的半胱氨酸蛋白酶-1(cleaved caspase-1)、气孔蛋白D的N端片段(GSDMD-N)等蛋白水平。结果显示,在体内实验中,Isor能显著改善小鼠肺组织的病理损伤状态,降低肺肿胀程度、BALF中蛋白水平、肺组织MPO水平、炎症因子IL-1β、IL-6、IL-18、TNF-α等的水平,抑制NLRP3/ASC/caspase-1轴及焦亡核心基因GS-DMD-N的高表达。在体外实验中,通过细胞增殖毒性实验确定了Isor的安全剂量。Isor能减少细胞死亡,抑制NLRP3/ASC/caspase-1轴、GSDMD-N及炎症因子的表达水平。综上所述,Isor可能通过调控NLRP3/ASC/caspase-1轴介导的细胞焦亡,从而发挥减轻ALI的效应。 展开更多
关键词 急性肺损伤 细胞焦亡 NLRP3/asc/caspase-1轴 巨噬细胞 异鼠李素
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What Classification of the Extent of Atheromatous Lesions on the Femoral Arterial Bifurcation for a Good Endovascular Therapeutic Indication?
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作者 M. Gaye P. A. Dieng +2 位作者 N. F. Sow M. Boufi A. G. Ciss 《World Journal of Cardiovascular Surgery》 2019年第12期171-176,共6页
The evaluation of the extension of the atheromatous lesion is essential for the planning of the endovascular technique at the level of the femoral arterial bifurcation. Therefore, we changed the classification of Azem... The evaluation of the extension of the atheromatous lesion is essential for the planning of the endovascular technique at the level of the femoral arterial bifurcation. Therefore, we changed the classification of Azema and applied it to a series of patients who had undergone open surgery of the femoral arterial bifurcation. This evaluation made it possible to have an idea of the distribution of atheromatous lesions in this region and to compare the efficiency of this modified classification of Azéma with others used in the literature. This modified classification of Azema is relevant and constitutes a decision-making tool for the endovascular therapeutic indications of femoral arterial bifurcation. 展开更多
关键词 classification Extension Athéromatous ENDOVascULAR Azema
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基于NLRP3/ASC/Caspase-1信号通路探讨肝复胶囊抗慢性肝损伤的作用机制
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作者 李敏仪 黄以蓉 +5 位作者 彭凯 彭继 谢锋 王祁 高璐 李敏 《山西医科大学学报》 2025年第1期28-35,共8页
目的 研究肝复胶囊(Ganfu capsule,GFC)对CCl4诱导的慢性肝损伤(chronic liver injury,CLI)大鼠模型的影响及作用机制。方法 将60只SD雄性大鼠随机分为空白组、模型组、秋水仙碱组(2×10^(-4) g/kg)及肝复胶囊低(GFC-L,0.781 3 g/kg... 目的 研究肝复胶囊(Ganfu capsule,GFC)对CCl4诱导的慢性肝损伤(chronic liver injury,CLI)大鼠模型的影响及作用机制。方法 将60只SD雄性大鼠随机分为空白组、模型组、秋水仙碱组(2×10^(-4) g/kg)及肝复胶囊低(GFC-L,0.781 3 g/kg)、中(GFC-M,1.562 5 g/kg)、高(GFC-H,3.125 g/kg)剂量组,每组10只。空白组不做处理,其余组大鼠均背部皮下注射40%CCl4花生油混合溶液造模,除首剂量按5 mL/kg外,每次注射剂量为3 mL/kg,每周2次,持续12周。造模4周后,给药组大鼠开始灌胃相应药物,空白组和模型组灌胃等量生理盐水,每日1次,持续8周。12周末,称量各组大鼠体质量后,处死大鼠,腹主动脉取血,收集大鼠肝脏。HE及Masson染色观察肝组织病理变化;生化试剂盒检测大鼠血清谷丙转氨酶(alanine aminotransferase,ALT)、谷草转氨酶(aspartate aminotransferase,AST);ELISA检测大鼠血清肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)、白细胞介素-1β(interleukin-1β,IL-1β)、IL-6水平;Western blot法检测各组大鼠肝组织中核苷酸结合寡聚化结构域样受体蛋白3(nod-like receptor protein 3,NLRP3)、凋亡相关斑点样蛋白(apoptosis associated speck-like protein containing a caspase activating recruitment domain,ASC)、半胱氨酸蛋白酶-1(cysteinyl aspartate specific proteinase-1,Caspase-1)蛋白表达。结果 与模型组比较,GFC各剂量组和秋水仙碱组大鼠体质量显著增加,肝组织炎症浸润及胶原蛋白沉积减少,血清中ALT、AST、TNF-α、IL-1β、IL-6水平明显降低(P<0.05),肝组织中NLRP3、ASC、Caspase-1蛋白表达下调(P<0.05),高剂量GFC改善CLI大鼠疗效优于秋水仙碱。结论 GFC可能通过下调NLRP3/ASC/Caspase-1信号通路,抑制炎症因子的表达,从而缓解CCl4诱导的肝脏炎症损伤,发挥保护肝脏作用。 展开更多
关键词 肝复胶囊 慢性肝损伤 NLRP3 asc CASPASE-1 炎症
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基于NLRP3/ASC/Caspase-1通路介导细胞焦亡的中药抗抑郁作用研究进展
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作者 孟士媛 汪尤文 田旭升 《中国医药导报》 2025年第13期91-95,114,共6页
抑郁症是一种高发性、复发性及多样性的精神障碍疾病,其发病机制复杂,尚未完全阐明。近年来,细胞焦亡作为一种由炎症小体激活的程序性细胞坏死方式,与抑郁症的病理机制关系密切。核苷酸结合寡聚结构域样受体蛋白3(NLRP3)炎症小体在细胞... 抑郁症是一种高发性、复发性及多样性的精神障碍疾病,其发病机制复杂,尚未完全阐明。近年来,细胞焦亡作为一种由炎症小体激活的程序性细胞坏死方式,与抑郁症的病理机制关系密切。核苷酸结合寡聚结构域样受体蛋白3(NLRP3)炎症小体在细胞焦亡和抑郁症的发展中可能起到中心介质作用。以NLRP3/ASC/Caspase-1为核心的经典细胞焦亡通路,通过调控炎症因子释放和神经炎症反应,成为抑郁症研究的热点方向。中药因其多靶点、多途径的作用特点,在抑郁症治疗中展现出独特优势,能对症调控,改善伴随症状且毒副作用较小,已得到临床广泛认可。本文基于NLRP3/ASC/Caspase-1通路介导的细胞焦亡机制,对中药干预抑郁症的研究进展进行总结与评述,旨在为抑郁症的发病机制探索及治疗策略提供新的理论依据和研究思路。 展开更多
关键词 中药 抑郁症 NLRP3/asc/Caspase-1通路 细胞焦亡 炎症小体
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Urban tree species classification based on multispectral airborne LiDAR 被引量:1
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作者 HU Pei-Lun CHEN Yu-Wei +3 位作者 Mohammad Imangholiloo Markus Holopainen WANG Yi-Cheng Juha Hyyppä 《红外与毫米波学报》 北大核心 2025年第2期211-216,共6页
Urban tree species provide various essential ecosystem services in cities,such as regulating urban temperatures,reducing noise,capturing carbon,and mitigating the urban heat island effect.The quality of these services... Urban tree species provide various essential ecosystem services in cities,such as regulating urban temperatures,reducing noise,capturing carbon,and mitigating the urban heat island effect.The quality of these services is influenced by species diversity,tree health,and the distribution and the composition of trees.Traditionally,data on urban trees has been collected through field surveys and manual interpretation of remote sensing images.In this study,we evaluated the effectiveness of multispectral airborne laser scanning(ALS)data in classifying 24 common urban roadside tree species in Espoo,Finland.Tree crown structure information,intensity features,and spectral data were used for classification.Eight different machine learning algorithms were tested,with the extra trees(ET)algorithm performing the best,achieving an overall accuracy of 71.7%using multispectral LiDAR data.This result highlights that integrating structural and spectral information within a single framework can improve the classification accuracy.Future research will focus on identifying the most important features for species classification and developing algorithms with greater efficiency and accuracy. 展开更多
关键词 multispectral airborne LiDAR machine learning tree species classification
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Classification and Endovascular treatment of the Spinal arteriovenous shunts:
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作者 S. Pongpech 《介入放射学杂志》 CSCD 2004年第S1期185-188,共4页
关键词 SAMS classification and Endovascular treatment of the Spinal arteriovenous shunts
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Impact of classification granularity on interdisciplinary performance assessment of research institutes and organizations 被引量:1
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作者 Jiandong Zhang Sonia Gruber Rainer Frietsch 《Journal of Data and Information Science》 2025年第2期61-79,共19页
Purpose:Interdisciplinary research has become a critical approach to addressing complex societal,economic,technological,and environmental challenges,driving innovation and integrating scientific knowledge.While interd... Purpose:Interdisciplinary research has become a critical approach to addressing complex societal,economic,technological,and environmental challenges,driving innovation and integrating scientific knowledge.While interdisciplinarity indicators are widely used to evaluate research performance,the impact of classification granularity on these assessments remains underexplored.Design/methodology/approach:This study investigates how different levels of classification granularity-macro,meso,and micro-affect the evaluation of interdisciplinarity in research institutes.Using a dataset of 262 institutes from four major German non-university organizations(FHG,HGF,MPG,WGL)from 2018 to 2022,we examine inconsistencies in interdisciplinarity across levels,analyze ranking changes,and explore the influence of institutional fields and research focus(applied vs.basic).Findings:Our findings reveal significant inconsistencies in interdisciplinarity across classification levels,with rankings varying substantially.Notably,the Fraunhofer Society(FHG),which performs well at the macro level,experiences significant ranking declines at meso and micro levels.Normalizing interdisciplinarity by research field confirmed that these declines persist.The research focus of institutes,whether applied,basic,or mixed,does not significantly explain the observed ranking dynamics.Research limitations:This study has only considered the publication-based dimension of institutional interdisciplinarity and has not explored other aspects.Practical implications:The findings provide insights for policymakers,research managers,and scholars to better interpret interdisciplinarity metrics and support interdisciplinary research effectively.Originality/value:This study underscores the critical role of classification granularity in interdisciplinarity assessment and emphasizes the need for standardized approaches to ensure robust and fair evaluations. 展开更多
关键词 Interdisciplinarity Paper-level classification system Organization evaluation
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YOLOCSP-PEST for Crops Pest Localization and Classification 被引量:1
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作者 Farooq Ali Huma Qayyum +2 位作者 Kashif Saleem Iftikhar Ahmad Muhammad Javed Iqbal 《Computers, Materials & Continua》 2025年第2期2373-2388,共16页
Preservation of the crops depends on early and accurate detection of pests on crops as they cause several diseases decreasing crop production and quality. Several deep-learning techniques have been applied to overcome... Preservation of the crops depends on early and accurate detection of pests on crops as they cause several diseases decreasing crop production and quality. Several deep-learning techniques have been applied to overcome the issue of pest detection on crops. We have developed the YOLOCSP-PEST model for Pest localization and classification. With the Cross Stage Partial Network (CSPNET) backbone, the proposed model is a modified version of You Only Look Once Version 7 (YOLOv7) that is intended primarily for pest localization and classification. Our proposed model gives exceptionally good results under conditions that are very challenging for any other comparable models especially conditions where we have issues with the luminance and the orientation of the images. It helps farmers working out on their crops in distant areas to determine any infestation quickly and accurately on their crops which helps in the quality and quantity of the production yield. The model has been trained and tested on 2 datasets namely the IP102 data set and a local crop data set on both of which it has shown exceptional results. It gave us a mean average precision (mAP) of 88.40% along with a precision of 85.55% and a recall of 84.25% on the IP102 dataset meanwhile giving a mAP of 97.18% on the local data set along with a recall of 94.88% and a precision of 97.50%. These findings demonstrate that the proposed model is very effective in detecting real-life scenarios and can help in the production of crops improving the yield quality and quantity at the same time. 展开更多
关键词 Deep learning classification of pests YOLOCSP-PEST pest detection
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Nondestructive detection and classification of impurities-containing seed cotton based on hyperspectral imaging and one-dimensional convolutional neural network 被引量:1
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作者 Yeqi Fei Zhenye Li +2 位作者 Tingting Zhu Zengtao Chen Chao Ni 《Digital Communications and Networks》 2025年第2期308-316,共9页
The cleanliness of seed cotton plays a critical role in the pre-treatment of cotton textiles,and the removal of impurity during the harvesting process directly determines the quality and market value of cotton textile... The cleanliness of seed cotton plays a critical role in the pre-treatment of cotton textiles,and the removal of impurity during the harvesting process directly determines the quality and market value of cotton textiles.By fusing band combination optimization with deep learning,this study aims to achieve more efficient and accurate detection of film impurities in seed cotton on the production line.By applying hyperspectral imaging and a one-dimensional deep learning algorithm,we detect and classify impurities in seed cotton after harvest.The main categories detected include pure cotton,conveyor belt,film covering seed cotton,and film adhered to the conveyor belt.The proposed method achieves an impurity detection rate of 99.698%.To further ensure the feasibility and practical application potential of this strategy,we compare our results against existing mainstream methods.In addition,the model shows excellent recognition performance on pseudo-color images of real samples.With a processing time of 11.764μs per pixel from experimental data,it shows a much improved speed requirement while maintaining the accuracy of real production lines.This strategy provides an accurate and efficient method for removing impurities during cotton processing. 展开更多
关键词 Seed cotton Film impurity Hyperspectral imaging Band optimization classification
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Automated ECG arrhythmia classification using hybrid CNN-SVM architectures 被引量:1
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作者 Amine Ben Slama Yessine Amri +1 位作者 Ahmed Fnaiech Hanene Sahli 《Journal of Electronic Science and Technology》 2025年第3期43-55,共13页
Diagnosing cardiac diseases relies heavily on electrocardiogram(ECG)analysis,but detecting myocardial infarction-related arrhythmias remains challenging due to irregular heartbeats and signal variations.Despite advanc... Diagnosing cardiac diseases relies heavily on electrocardiogram(ECG)analysis,but detecting myocardial infarction-related arrhythmias remains challenging due to irregular heartbeats and signal variations.Despite advancements in machine learning,achieving both high accuracy and low computational cost for arrhythmia classification remains a critical issue.Computer-aided diagnosis systems can play a key role in early detection,reducing mortality rates associated with cardiac disorders.This study proposes a fully automated approach for ECG arrhythmia classification using deep learning and machine learning techniques to improve diagnostic accuracy while minimizing processing time.The methodology consists of three stages:1)preprocessing,where ECG signals undergo noise reduction and feature extraction;2)feature Identification,where deep convolutional neural network(CNN)blocks,combined with data augmentation and transfer learning,extract key parameters;3)classification,where a hybrid CNN-SVM model is employed for arrhythmia recognition.CNN-extracted features were fed into a binary support vector machine(SVM)classifier,and model performance was assessed using five-fold cross-validation.Experimental findings demonstrated that the CNN2 model achieved 85.52%accuracy,while the hybrid CNN2-SVM approach significantly improved accuracy to 97.33%,outperforming conventional methods.This model enhances classification efficiency while reducing computational complexity.The proposed approach bridges the gap between accuracy and processing speed in ECG arrhythmia classification,offering a promising solution for real-time clinical applications.Its superior performance compared to nonlinear classifiers highlights its potential for improving automated cardiac diagnosis. 展开更多
关键词 ARRHYTHMIA classification Convolutional neural networks ECG signals Support vector machine
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Various classification methods for diabetes mellitus in the management of blood glucose control 被引量:1
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作者 Qing Jiang Yun Hu Jian-Hua Ma 《World Journal of Diabetes》 2025年第5期1-7,共7页
In the era of precision medicine,the classification of diabetes mellitus has evolved beyond the traditional categories.Various classification methods now account for a multitude of factors,including variations in spec... In the era of precision medicine,the classification of diabetes mellitus has evolved beyond the traditional categories.Various classification methods now account for a multitude of factors,including variations in specific genes,type ofβ-cell impairment,degree of insulin resistance,and clinical characteristics of metabolic profiles.Improved classification methods enable healthcare providers to formulate blood glucose management strategies more precisely.Applying these updated classification systems,will assist clinicians in further optimising treatment plans,including targeted drug therapies,personalized dietary advice,and specific exercise plans.Ultimately,this will facilitate stricter blood glucose control,minimize the risks of hypoglycaemia and hyperglycaemia,and reduce long-term complications associated with diabetes. 展开更多
关键词 Diabetes classification Glycaemic control Personalised treatment Soft clustering Precision medicine
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Classification and provenance of exotic impact glasses in Chang’e-5 lunar soil 被引量:1
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作者 YunHong Fan BiWen Wang +3 位作者 Wei Yang QiuLi Li HuiJuan Zhang ShiTou Wu 《Earth and Planetary Physics》 2025年第6期1099-1112,共14页
Lunar impact glasses have been identified as crucial indicators of geochemical information regarding their source regions. Impact glasses can be categorized as either local or exotic. Those preserving geochemical sign... Lunar impact glasses have been identified as crucial indicators of geochemical information regarding their source regions. Impact glasses can be categorized as either local or exotic. Those preserving geochemical signatures matching local lithologies (e.g., mare basalts or their single minerals) or regolith bulk soil compositions are classified as “local”. Otherwise, they could be defined as “exotic”. The analysis of exotic glasses provides the opportunity to explore previously unsampled lunar areas. This study focuses on the identification of exotic glasses within the Chang’e-5 (CE-5) soil sample by analyzing the trace elements of 28 impact glasses with distinct major element compositions in comparison with the CE-5 bulk soil. However, the results indicate that 18 of the analyzed glasses exhibit trace element compositions comparable to those of the local CE-5 materials. In particular, some of them could match the local single mineral component in major and trace elements, suggesting a local origin. Therefore, it is recommended that the investigation be expanded from using major elements to including nonvolatile trace elements, with a view to enhancing our understanding on the provenance of lunar impact glasses. To achieve a more accurate identification of exotic glasses within the CE-5 soil sample, a novel classification plot of Mg# versus La is proposed. The remaining 10 glasses, which exhibit diverse trace element variations, were identified as exotic. A comparative analysis of their chemical characteristics with remote sensing data indicates that they may have originated from the Aristarchus, Mairan, Sharp, or Pythagoras craters. This study elucidates the classification and possible provenance of exotic materials within the CE-5 soil sample, thereby providing constraints for the enhanced identification of local and exotic components at the CE-5 landing site. 展开更多
关键词 Chang’e-5 impact glass exotic materials classification PROVENANCE
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Three-Stage Transfer Learning with AlexNet50 for MRI Image Multi-Class Classification with Optimal Learning Rate
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作者 Suganya Athisayamani A.Robert Singh +1 位作者 Gyanendra Prasad Joshi Woong Cho 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期155-183,共29页
In radiology,magnetic resonance imaging(MRI)is an essential diagnostic tool that provides detailed images of a patient’s anatomical and physiological structures.MRI is particularly effective for detecting soft tissue... In radiology,magnetic resonance imaging(MRI)is an essential diagnostic tool that provides detailed images of a patient’s anatomical and physiological structures.MRI is particularly effective for detecting soft tissue anomalies.Traditionally,radiologists manually interpret these images,which can be labor-intensive and time-consuming due to the vast amount of data.To address this challenge,machine learning,and deep learning approaches can be utilized to improve the accuracy and efficiency of anomaly detection in MRI scans.This manuscript presents the use of the Deep AlexNet50 model for MRI classification with discriminative learning methods.There are three stages for learning;in the first stage,the whole dataset is used to learn the features.In the second stage,some layers of AlexNet50 are frozen with an augmented dataset,and in the third stage,AlexNet50 with an augmented dataset with the augmented dataset.This method used three publicly available MRI classification datasets:Harvard whole brain atlas(HWBA-dataset),the School of Biomedical Engineering of Southern Medical University(SMU-dataset),and The National Institute of Neuroscience and Hospitals brain MRI dataset(NINS-dataset)for analysis.Various hyperparameter optimizers like Adam,stochastic gradient descent(SGD),Root mean square propagation(RMS prop),Adamax,and AdamW have been used to compare the performance of the learning process.HWBA-dataset registers maximum classification performance.We evaluated the performance of the proposed classification model using several quantitative metrics,achieving an average accuracy of 98%. 展开更多
关键词 MRI TUMORS classification AlexNet50 transfer learning hyperparameter tuning OPTIMIZER
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Deep Learning and Artificial Intelligence-Driven Advanced Methods for Acute Lymphoblastic Leukemia Identification and Classification: A Systematic Review 被引量:1
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作者 Syed Ijaz Ur Rahman Naveed Abbas +5 位作者 Sikandar Ali Muhammad Salman Ahmed Alkhayat Jawad Khan Dildar Hussain Yeong Hyeon Gu 《Computer Modeling in Engineering & Sciences》 2025年第2期1199-1231,共33页
Automatic detection of Leukemia or blood cancer is one of the most challenging tasks that need to be addressed in the healthcare system.Analysis of white blood cells(WBCs)in the blood or bone marrow microscopic slide ... Automatic detection of Leukemia or blood cancer is one of the most challenging tasks that need to be addressed in the healthcare system.Analysis of white blood cells(WBCs)in the blood or bone marrow microscopic slide images play a crucial part in early identification to facilitate medical experts.For Acute Lymphocytic Leukemia(ALL),the most preferred part of the blood or marrow is to be analyzed by the experts before it spreads in the whole body and the condition becomes worse.The researchers have done a lot of work in this field,to demonstrate a comprehensive analysis few literature reviews have been published focusing on various artificial intelligence-based techniques like machine and deep learning detection of ALL.The systematic review has been done in this article under the PRISMA guidelines which presents the most recent advancements in this field.Different image segmentation techniques were broadly studied and categorized from various online databases like Google Scholar,Science Direct,and PubMed as image processing-based,traditional machine and deep learning-based,and advanced deep learning-based models were presented.Convolutional Neural Networks(CNN)based on traditional models and then the recent advancements in CNN used for the classification of ALL into its subtypes.A critical analysis of the existing methods is provided to offer clarity on the current state of the field.Finally,the paper concludes with insights and suggestions for future research,aiming to guide new researchers in the development of advanced automated systems for detecting life-threatening diseases. 展开更多
关键词 Acute lymphoblastic bone marrow SEGMENTATION classification machine learning deep learning convolutional neural network
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TMC-GCN: Encrypted Traffic Mapping Classification Method Based on Graph Convolutional Networks 被引量:1
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作者 Baoquan Liu Xi Chen +2 位作者 Qingjun Yuan Degang Li Chunxiang Gu 《Computers, Materials & Continua》 2025年第2期3179-3201,共23页
With the emphasis on user privacy and communication security, encrypted traffic has increased dramatically, which brings great challenges to traffic classification. The classification method of encrypted traffic based... With the emphasis on user privacy and communication security, encrypted traffic has increased dramatically, which brings great challenges to traffic classification. The classification method of encrypted traffic based on GNN can deal with encrypted traffic well. However, existing GNN-based approaches ignore the relationship between client or server packets. In this paper, we design a network traffic topology based on GCN, called Flow Mapping Graph (FMG). FMG establishes sequential edges between vertexes by the arrival order of packets and establishes jump-order edges between vertexes by connecting packets in different bursts with the same direction. It not only reflects the time characteristics of the packet but also strengthens the relationship between the client or server packets. According to FMG, a Traffic Mapping Classification model (TMC-GCN) is designed, which can automatically capture and learn the characteristics and structure information of the top vertex in FMG. The TMC-GCN model is used to classify the encrypted traffic. The encryption stream classification problem is transformed into a graph classification problem, which can effectively deal with data from different data sources and application scenarios. By comparing the performance of TMC-GCN with other classical models in four public datasets, including CICIOT2023, ISCXVPN2016, CICAAGM2017, and GraphDapp, the effectiveness of the FMG algorithm is verified. The experimental results show that the accuracy rate of the TMC-GCN model is 96.13%, the recall rate is 95.04%, and the F1 rate is 94.54%. 展开更多
关键词 Encrypted traffic classification deep learning graph neural networks multi-layer perceptron graph convolutional networks
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A novel method for clustering cellular data to improve classification
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作者 Diek W.Wheeler Giorgio A.Ascoli 《Neural Regeneration Research》 SCIE CAS 2025年第9期2697-2705,共9页
Many fields,such as neuroscience,are experiencing the vast prolife ration of cellular data,underscoring the need fo r organizing and interpreting large datasets.A popular approach partitions data into manageable subse... Many fields,such as neuroscience,are experiencing the vast prolife ration of cellular data,underscoring the need fo r organizing and interpreting large datasets.A popular approach partitions data into manageable subsets via hierarchical clustering,but objective methods to determine the appropriate classification granularity are missing.We recently introduced a technique to systematically identify when to stop subdividing clusters based on the fundamental principle that cells must differ more between than within clusters.Here we present the corresponding protocol to classify cellular datasets by combining datadriven unsupervised hierarchical clustering with statistical testing.These general-purpose functions are applicable to any cellular dataset that can be organized as two-dimensional matrices of numerical values,including molecula r,physiological,and anatomical datasets.We demonstrate the protocol using cellular data from the Janelia MouseLight project to chara cterize morphological aspects of neurons. 展开更多
关键词 cellular data clustering dendrogram data classification Levene's one-tailed statistical test unsupervised hierarchical clustering
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