Circulose,a global leader in recycled pulp production,hasreached a strategic partnership agreement with Tangshan SanyouChemical Fiber,a front-runner in the cellulose fiber industry.Thiscollaboration marks a significan...Circulose,a global leader in recycled pulp production,hasreached a strategic partnership agreement with Tangshan SanyouChemical Fiber,a front-runner in the cellulose fiber industry.Thiscollaboration marks a significant milestone in the commercializa-tion and scaling of CIRCULOSER,whle also propelling TangshanSanyou's brand toward greater international recognition.展开更多
Owing to eccentricity and inclination, circularity of a cylindrical workpiece cannot be measured precisely by a circularity measuring machine when the workpiece has a small dimension(diameter ≤ 3 mm). In this paper, ...Owing to eccentricity and inclination, circularity of a cylindrical workpiece cannot be measured precisely by a circularity measuring machine when the workpiece has a small dimension(diameter ≤ 3 mm). In this paper, with the aim of solving this problem, circularity metrology of a small cylindrical workpiece using a segmenting scanning method is analyzed. The cross-sectional circle of the cylinder is segmented into several equivalent arcs for measurement by a two-dimensional coordinate measuring machine(profilometer). The circularity contour is obtained by stitching together arc contours obtained by data processing of the coordinates. Different segmenting patterns for coordinate scanning are considered. Measurement results are presented for three segmentation patterns, with 8, 10, and 12 equal segments, respectively.These results are evaluated in terms of the matching coefficient between neighboring arc contours on circumferential stitching, the Euclidean distance between neighboring arc contours on radial stitching, and the curvature of the arcs. From these evaluations, it is found that as the number of segments is increased, the matching coefficient increases from 0.14 to 0.50, the Euclidean distance decreases from 32 nm to 26 nm,and the curvature becomes close to the standard value.展开更多
Background: The shape of the capitellum has been traditionally described in anatomy books as part of a sphere. Alteration in the capitellar morphology following pathologies such as fractures, osteochondrosis, and dege...Background: The shape of the capitellum has been traditionally described in anatomy books as part of a sphere. Alteration in the capitellar morphology following pathologies such as fractures, osteochondrosis, and degenerative arthritis has been associated with less optimum functional results. Aim: To define the relationship between the sphericity of the capitellar morphology as measured on trauma series plain radiographs and the elbow range of motion. Methods: 40 patients were included in the study. All patients recruited from the upper limb clinics presented with non-elbow joint-related complaints. The elbow range of motion was measured using a standardized technique. Digital anteroposterior and lateral radiographs of patients’ elbows were used to measure capitellar circularity using the ImageJ processing program and circularity calculation equation. Correlation analyses were conducted between the degree of capitellar sphericity and elbow range of motion. Results: The results of measurements from the anteroposterior radiographs showed a positive correlation between increased circularity and an increase in the range of flexion, pronation, and supination. The range of extension decreased with the increased circularity of the capitellum. This trend was repeated with measures of lateral radiographs but was statistically not significant. Conclusion: Native capitellar circularity has an impact on the elbow range of motion. This should be put into consideration when dealing with pathologies that affect capitellar morphology.展开更多
To reduce the stitching error of circularity measurement of small cylindrical workpieces(Diameter less than 3 mm)by the segmenting-stitching method,arc contour extraction is analyzed in this paper.The coordinates of c...To reduce the stitching error of circularity measurement of small cylindrical workpieces(Diameter less than 3 mm)by the segmenting-stitching method,arc contour extraction is analyzed in this paper.The coordinates of cross-sectional circle of a small cylindrical part are segmented into several equal arcs to be obtained by a two-dimensional coordinate measuring machine.The circularity contour of the small cylindrical part can be formed by stitching a series of arc contours which are calculated by the obtained arc coordinate data.Due to the different measuring pressure angles of different measuring positions,the accuracy of obtained arc coordinate points is different.The bigger the pressure angle is,the accurate the obtained arc coordinate data are.The experiments show that the accuracy of two ends of the arc data is not as good as the central part.Therefore,the two ends of the obtained arc data are appropriately to be cut off,namely,only the central part of the arc data are extracted to be used for the stitching.As a result,the mean value of the matching coefficient is enhanced by 12%,the deviation between the overlap part of the neighbouring arc contour is reduced by 26%,and the average curvature of the arc contours is improved with the extraction method.Thus,the accuracy of the stitched circularity contour can be improved by this extraction procedure in the segmenting-stitching method for the circularity measurement of the small cylindrical parts.展开更多
To address the alignment and measuring force problem in the segmenting-stitching technique for the circularity metrology of small cylindrical workpieces(diameter less than 1.5 mm and length less than 10 mm),a magnet c...To address the alignment and measuring force problem in the segmenting-stitching technique for the circularity metrology of small cylindrical workpieces(diameter less than 1.5 mm and length less than 10 mm),a magnet combination jig method is proposed.A small round magnet is attached between the round magnetic jig and small cylinder,and the other end of the small cylindrical workpiece is attached to some cylindrical magnets.Thus,the smaller cylinder can be put in the V-groove and measured successfully with the magnet combination.For verifying the advantage of the magnet combination jig,four measurement quality evaluations are proposed:the circumferential deviation of neighbor arc contours,radial deviation of neighbor arc contours,angle of inclination between the V-groove and small cylinder,and curvature of the obtained arc.The results show that the matching coefficient is enhanced by 98%,the Euclidean distance of overlap parts of neighbor arc contours is reduced by 68%,the position error is reduced 27%,and the average curvature of the arc contours is improved.It can be concluded that the measuring quality can be enhanced prominently by this magnet combination method for the segmenting-stitching method.展开更多
Dear Editor,The nice manuscript of Reddy et al^([1])regarding comparison of capsulotomy using three different techniques raises some issues which I will discuss in short.Use of newer technologies in phacoemulsificatio...Dear Editor,The nice manuscript of Reddy et al^([1])regarding comparison of capsulotomy using three different techniques raises some issues which I will discuss in short.Use of newer technologies in phacoemulsification is always of interest to researchers and the authors have compared three techniques which will help us choose the best technique.The study is properly designed and analyzed.I was impressed by detailed analysis and discussion.展开更多
Resource depletion and environmental degradation have fueled a burgeoning discipline of anthropogenic circularity since the 2010s.It generally consists of waste reuse,remanufacturing,recycling,and recovery.Circular ec...Resource depletion and environmental degradation have fueled a burgeoning discipline of anthropogenic circularity since the 2010s.It generally consists of waste reuse,remanufacturing,recycling,and recovery.Circular economy and“zero-waste”cities are sweeping the globe in their current practices to address the world’s grand concerns linked to resources,the environment,and industry.Meanwhile,metal criticality and carbon neutrality,which have become increasingly popular in recent years,denote the material's feature and state,respectively.The goal of this article is to determine how circularity,criticality,and neutrality are related.Upscale anthropogenic circularity has the potential to expand the metal supply and,as a result,reduce metal criticality.China barely accomplished 15%of its potential emission reduction by recycling iron,copper,and aluminum.Anthropogenic circularity has a lot of room to achieve a win-win objective,which is to reduce metal criticality while also achieving carbon neutrality in a near closed-loop cycle.Major barriers or challenges for conducting anthropogenic circularity are deriving from the inadequacy of life-cycle insight governance and the emergence of anthropogenic circularity discipline.Material flow analysis and life cycle assessment are the central methodologies to identify the hidden problems.Mineral processing and smelting,as well as end-of-life management,are indicated as critical priority areas for enhancing anthropogenic circularity.展开更多
Alzheimer's disease,a progressively degenerative neurological disorder,is the most common cause of dementia in the elderly.While its precise etiology remains unclear,researchers have identified diverse pathologica...Alzheimer's disease,a progressively degenerative neurological disorder,is the most common cause of dementia in the elderly.While its precise etiology remains unclear,researchers have identified diverse pathological characteristics and molecular pathways associated with its progression.Advances in scientific research have increasingly highlighted the crucial role of non-coding RNAs in the progression of Alzheimer's disease.These non-coding RNAs regulate several biological processes critical to the advancement of the disease,offering promising potential as therapeutic targets and diagnostic biomarkers.Therefore,this review aims to investigate the underlying mechanisms of Alzheimer's disease onset,with a particular focus on microRNAs,long non-coding RNAs,and circular RNAs associated with the disease.The review elucidates the potential pathogenic processes of Alzheimer's disease and provides a detailed description of the synthesis mechanisms of the three aforementioned non-coding RNAs.It comprehensively summarizes the various non-coding RNAs that have been identified to play key regulatory roles in Alzheimer's disease,as well as how these noncoding RNAs influence the disease's progression by regulating gene expression and protein functions.For example,miR-9 targets the UBE4B gene,promoting autophagy-mediated degradation of Tau protein,thereby reducing Tau accumulation and delaying Alzheimer's disease progression.Conversely,the long non-coding RNA BACE1-AS stabilizes BACE1 mRNA,promoting the generation of amyloid-βand accelerating Alzheimer's disease development.Additionally,circular RNAs play significant roles in regulating neuroinflammatory responses.By integrating insights from these regulatory mechanisms,there is potential to discover new therapeutic targets and potential biomarkers for early detection and management of Alzheimer's disease.This review aims to enhance the understanding of the relationship between Alzheimer's disease and non-coding RNAs,potentially paving the way for early detection and novel treatment strategies.展开更多
Sphericity,a measure of how much a particle’s shape deviates from spherical,is useful as a shape factorwhen characterizing particulate materials.However,particle surface areas,required when determiningthe sphericity,...Sphericity,a measure of how much a particle’s shape deviates from spherical,is useful as a shape factorwhen characterizing particulate materials.However,particle surface areas,required when determiningthe sphericity,are very difficult to measure.As a result,the circularity,derivable from microscopic views,is often measured instead and assumed to be equal to the sphericity.This paper shows that the twoquantities are generally not equal for simple non-spherical shapes and provides advice on improving theestimation of sphericity from circularity.展开更多
Stroke-induced alterations in cerebral blood flow trigger neurovascular remodeling,as manifested by the blood-brain barrier dysfunction and subs equent neurovascular repair activities such as angiogenesis.This process...Stroke-induced alterations in cerebral blood flow trigger neurovascular remodeling,as manifested by the blood-brain barrier dysfunction and subs equent neurovascular repair activities such as angiogenesis.This process involves neurovascular communication that facilitates the transport of mediators among cerebrovascular endothelial cells,pericytes,glial cells,and neurons,thereby transmitting signals from donor to recipient cells to elicit a collaborative response.展开更多
This paper aims to contribute to the development of spatial criteria for adaptive capacity,which is identified as one important factor for the transition towards more circular housing design.The paper focuses on the k...This paper aims to contribute to the development of spatial criteria for adaptive capacity,which is identified as one important factor for the transition towards more circular housing design.The paper focuses on the kitchen,as an important function of the home which is connected to large resource flows and is exposed to frequent renovations and replacements.This paper identifies spatial characteristics of the kitchen and evaluates their potential to accommodate circular solutions focusing on adaptive capacity.As a first step,previous literature on the spatial characteristics of kitchens and indicators that support adaptability is reviewed.These are then used to develop an analytical framework to assess the adaptive capacity and circularity potential of 3624 kitchens in contemporary Swedish apartments.A qualitative approach in combination with quantitative methods is employed to analyse the selected sample.The main contributions of this paper include its spatial analytical framework,its descriptive presentation of contemporary kitchen and apartment designs,and its adaptive capacity assessment of the studied kitchens.The results point out that although the overcapacity of the floor area of kitchens and apartments can have significance for adaptability,it is not the only determinative spatial characteristics.The windows’location and distribution,the number of door openings and traffic zones,the shafts’location and accessibility from multiple rooms,the room typology and the kitchen typology can improve the adaptive capacity and circularity potential of kitchens and dwellings.The findings show that in contemporary floorplans advantageous design solutions connected to the identified spatial characteristics are not applied in a systematic way.Further research is necessary to define the exact measures of the individual spatial characteristics and their combined application in multiresidential floorplan design.展开更多
Several factors overlap in making urban heritage conservation vulnerable in terms of long-term sustainability.The purpose of this study is to offer insights into the dynamic role that heritage governance plays in the ...Several factors overlap in making urban heritage conservation vulnerable in terms of long-term sustainability.The purpose of this study is to offer insights into the dynamic role that heritage governance plays in the current sustainability debate.This purpose is achieved by investigating the shift from a‘governing for culture’approach to a‘governing through culture’approach in heritage conservation.Subsequently,a case is built for a circularity-based conservation strategy applicable to the governance of historic cities.Different indicators of the circular governance approach are considered,and useful data are collected in comparative form.The cross-matching relationship between the factors is then evaluated by employing the analytic hierarchy process(AHP)on the collected data.As a test case,the conservation strategy of the Medina of Tunis is presented.For a more general conservation model,case-specific data are acquired.Finally,the same framework is applied to compare the case-dependent and case-independent data to define an integrated conservation framework.The obtained results show that the knowledge and data exchange factor,carries the highest significance.This result translates into heritage-led urban regeneration through knowledge sharing and the effective redistribution of cultural activities in historic city centres.展开更多
Acute ischemic stroke is a clinical emergency and a condition with high morbidity,mortality,and disability.Accurate predictive,diagnostic,and prognostic biomarkers and effective therapeutic targets for acute ischemic ...Acute ischemic stroke is a clinical emergency and a condition with high morbidity,mortality,and disability.Accurate predictive,diagnostic,and prognostic biomarkers and effective therapeutic targets for acute ischemic stroke remain undetermined.With innovations in high-throughput gene sequencing analysis,many aberrantly expressed non-coding RNAs(ncRNAs)in the brain and peripheral blood after acute ischemic stroke have been found in clinical samples and experimental models.Differentially expressed ncRNAs in the post-stroke brain were demonstrated to play vital roles in pathological processes,leading to neuroprotection or deterioration,thus ncRNAs can serve as therapeutic targets in acute ischemic stroke.Moreover,distinctly expressed ncRNAs in the peripheral blood can be used as biomarkers for acute ischemic stroke prediction,diagnosis,and prognosis.In particular,ncRNAs in peripheral immune cells were recently shown to be involved in the peripheral and brain immune response after acute ischemic stroke.In this review,we consolidate the latest progress of research into the roles of ncRNAs(microRNAs,long ncRNAs,and circular RNAs)in the pathological processes of acute ischemic stroke–induced brain damage,as well as the potential of these ncRNAs to act as biomarkers for acute ischemic stroke prediction,diagnosis,and prognosis.Findings from this review will provide novel ideas for the clinical application of ncRNAs in acute ischemic stroke.展开更多
A tunable oxidization and reduction strategy was proposed to directly regenerate spent LiFePO_(4)/C cathode materials by oxidizing excessive carbon powders with the addition of FePO_(4).Experimental results indicate t...A tunable oxidization and reduction strategy was proposed to directly regenerate spent LiFePO_(4)/C cathode materials by oxidizing excessive carbon powders with the addition of FePO_(4).Experimental results indicate that spent LiFePO_(4)/C cathode materials with good performance can be regenerated by roasting at 650℃ for 11 h with the addition ofLi_(2)CO_(3),FePO_(4),V_(2)O_(5),and glucose.V_(2)O_(5) is added to improve the cycle performance of regenerated cathode materials.Glucose is used to revitalize the carbon layers on the surface of spent LiFePO_(4)/C particles for improving their conductivity.The regenerated V-doped LiFePO_(4)/C shows an excellent electrochemical performance with the discharge specific capacity of 161.36 mA·h/g at 0.2C,under which the capacity retention is 97.85%after 100 cycles.展开更多
With the continuous increase in the disposal volume of spent lithium-ion batteries(LIBs),properly recycling spent LIBs has become essential for the advancement of the circular economy.This study presents a systematic ...With the continuous increase in the disposal volume of spent lithium-ion batteries(LIBs),properly recycling spent LIBs has become essential for the advancement of the circular economy.This study presents a systematic analysis of the chlorination roasting kinetics and proposes a new two-step chlorination roasting process that integrates thermodynamics for the recycling of LIB cathode materials.The activation energy for the chloride reaction was 88.41 kJ/mol according to thermogravimetric analysis–derivative thermogravimetry data obtained by using model-free,model-fitting,and Z(α)function(αis conversion rate).Results indicated that the reaction was dominated by the first-order(F1)model when the conversion rate was less than or equal to 0.5 and shifted to the second-order(F2)model when the conversion rate exceeded 0.5.Optimal conditions were determined by thoroughly investigating the effects of roasting temperature,roasting time,and the mass ratio of NH_(4)Cl to LiCoO_(2).Under the optimal conditions,namely 400℃,20 min,and NH_(4)Cl/LiCoO_(2)mass ratio of 3:1,the leaching efficiency of Li and Co reached 99.43% and 99.05%,respectively.Analysis of the roasted products revealed that valuable metals in LiCoO_(2)transformed into CoCl_(2) and LiCl.Furthermore,the reaction mechanism was elucidated,providing insights for the establishment of a novel low-temperature chlorination roasting technology based on a crystal structure perspective.This technology can guide the development of LIB recycling processes with low energy consumption,low secondary pollution,high recovery efficiency,and high added value.展开更多
Multiple functional metasurfaces with high information capacity have attracted considerable attention from researchers.This study proposes a 2-bit tunable spin-decoupled coded metasurface designed for the terahertz ba...Multiple functional metasurfaces with high information capacity have attracted considerable attention from researchers.This study proposes a 2-bit tunable spin-decoupled coded metasurface designed for the terahertz band,which utilizes the tunable properties of Dirac semimetals(DSM)to create a novel multilayer structure.By incorporating both geometric and propagating phases into the metasurface design,we can effectively control the electromagnetic wave.When the Fermi level(EF)of the DSM is set at 6 meV,the electromagnetic wave is manipulated by the gold patch embedded in the DSM film,operating at a frequency of 1.3 THz.When the EF of the DSM is set at 80 meV,the electromagnetic wave is manipulated by the DSM patch,operating at a frequency of 1.4 THz.Both modes enable independent control of beam splitting under left-rotating circularly polarized(LCP)and rightrotating circularly polarized(RCP)wave excitation,resulting in the generation of vortex beams with distinct orbital angular momentum(OAM)modes.The findings of this study hold significant potential for enhancing information capacity and polarization multiplexing techniques in wireless communications.展开更多
The development of sustainable sludge management systems requires looking at them with a new vision in which the concepts of SD(Sustainable Development)must integrate those of CE(Circular Economy),both concepts subjec...The development of sustainable sludge management systems requires looking at them with a new vision in which the concepts of SD(Sustainable Development)must integrate those of CE(Circular Economy),both concepts subject to the principles of TD(Thermodynamics),thus allowing the adoption of actions that are all the more effective the more complete the evaluation of the social dimension has been.This involves a new“Way of thinking”which sees the sludge system as the“Locomotive”of the entire wastewater/sludge treatment train and is developed through“Ways of acting”which includes both“Technical”actions to maximize recoveries of useful materials and/or or energy,and“Socio/Institutional”actions to overcome barriers linked to local cultures and traditions,also considering that the specific local context heavily influences the choices capable of satisfying the concepts of CE.It follows the need of issuing realistic and applicable regulations and overcoming social barriers,such as lack of infrastructure and/or qualified personnel,to achieve an effective integration of the concepts of CE with the more general ones of sustainability.展开更多
文摘Circulose,a global leader in recycled pulp production,hasreached a strategic partnership agreement with Tangshan SanyouChemical Fiber,a front-runner in the cellulose fiber industry.Thiscollaboration marks a significant milestone in the commercializa-tion and scaling of CIRCULOSER,whle also propelling TangshanSanyou's brand toward greater international recognition.
基金supported by the National Defense Basic Scientific Research Program of China(Grant No.JCKY2019427D002).
文摘Owing to eccentricity and inclination, circularity of a cylindrical workpiece cannot be measured precisely by a circularity measuring machine when the workpiece has a small dimension(diameter ≤ 3 mm). In this paper, with the aim of solving this problem, circularity metrology of a small cylindrical workpiece using a segmenting scanning method is analyzed. The cross-sectional circle of the cylinder is segmented into several equivalent arcs for measurement by a two-dimensional coordinate measuring machine(profilometer). The circularity contour is obtained by stitching together arc contours obtained by data processing of the coordinates. Different segmenting patterns for coordinate scanning are considered. Measurement results are presented for three segmentation patterns, with 8, 10, and 12 equal segments, respectively.These results are evaluated in terms of the matching coefficient between neighboring arc contours on circumferential stitching, the Euclidean distance between neighboring arc contours on radial stitching, and the curvature of the arcs. From these evaluations, it is found that as the number of segments is increased, the matching coefficient increases from 0.14 to 0.50, the Euclidean distance decreases from 32 nm to 26 nm,and the curvature becomes close to the standard value.
文摘Background: The shape of the capitellum has been traditionally described in anatomy books as part of a sphere. Alteration in the capitellar morphology following pathologies such as fractures, osteochondrosis, and degenerative arthritis has been associated with less optimum functional results. Aim: To define the relationship between the sphericity of the capitellar morphology as measured on trauma series plain radiographs and the elbow range of motion. Methods: 40 patients were included in the study. All patients recruited from the upper limb clinics presented with non-elbow joint-related complaints. The elbow range of motion was measured using a standardized technique. Digital anteroposterior and lateral radiographs of patients’ elbows were used to measure capitellar circularity using the ImageJ processing program and circularity calculation equation. Correlation analyses were conducted between the degree of capitellar sphericity and elbow range of motion. Results: The results of measurements from the anteroposterior radiographs showed a positive correlation between increased circularity and an increase in the range of flexion, pronation, and supination. The range of extension decreased with the increased circularity of the capitellum. This trend was repeated with measures of lateral radiographs but was statistically not significant. Conclusion: Native capitellar circularity has an impact on the elbow range of motion. This should be put into consideration when dealing with pathologies that affect capitellar morphology.
基金supported by the National Defense Basic Scientific Research Program of China(Grant numbers JCKY2019427D002)
文摘To reduce the stitching error of circularity measurement of small cylindrical workpieces(Diameter less than 3 mm)by the segmenting-stitching method,arc contour extraction is analyzed in this paper.The coordinates of cross-sectional circle of a small cylindrical part are segmented into several equal arcs to be obtained by a two-dimensional coordinate measuring machine.The circularity contour of the small cylindrical part can be formed by stitching a series of arc contours which are calculated by the obtained arc coordinate data.Due to the different measuring pressure angles of different measuring positions,the accuracy of obtained arc coordinate points is different.The bigger the pressure angle is,the accurate the obtained arc coordinate data are.The experiments show that the accuracy of two ends of the arc data is not as good as the central part.Therefore,the two ends of the obtained arc data are appropriately to be cut off,namely,only the central part of the arc data are extracted to be used for the stitching.As a result,the mean value of the matching coefficient is enhanced by 12%,the deviation between the overlap part of the neighbouring arc contour is reduced by 26%,and the average curvature of the arc contours is improved with the extraction method.Thus,the accuracy of the stitched circularity contour can be improved by this extraction procedure in the segmenting-stitching method for the circularity measurement of the small cylindrical parts.
基金supported by the National Defense Basic Scientific Research Program of China(Grant numbers JCKY2019427D002).
文摘To address the alignment and measuring force problem in the segmenting-stitching technique for the circularity metrology of small cylindrical workpieces(diameter less than 1.5 mm and length less than 10 mm),a magnet combination jig method is proposed.A small round magnet is attached between the round magnetic jig and small cylinder,and the other end of the small cylindrical workpiece is attached to some cylindrical magnets.Thus,the smaller cylinder can be put in the V-groove and measured successfully with the magnet combination.For verifying the advantage of the magnet combination jig,four measurement quality evaluations are proposed:the circumferential deviation of neighbor arc contours,radial deviation of neighbor arc contours,angle of inclination between the V-groove and small cylinder,and curvature of the obtained arc.The results show that the matching coefficient is enhanced by 98%,the Euclidean distance of overlap parts of neighbor arc contours is reduced by 68%,the position error is reduced 27%,and the average curvature of the arc contours is improved.It can be concluded that the measuring quality can be enhanced prominently by this magnet combination method for the segmenting-stitching method.
文摘Dear Editor,The nice manuscript of Reddy et al^([1])regarding comparison of capsulotomy using three different techniques raises some issues which I will discuss in short.Use of newer technologies in phacoemulsification is always of interest to researchers and the authors have compared three techniques which will help us choose the best technique.The study is properly designed and analyzed.I was impressed by detailed analysis and discussion.
基金supported by the National Natural Sciences Foundation of China(No.92062111)the National Key R&D Program of China(No.2019YFC1908501).
文摘Resource depletion and environmental degradation have fueled a burgeoning discipline of anthropogenic circularity since the 2010s.It generally consists of waste reuse,remanufacturing,recycling,and recovery.Circular economy and“zero-waste”cities are sweeping the globe in their current practices to address the world’s grand concerns linked to resources,the environment,and industry.Meanwhile,metal criticality and carbon neutrality,which have become increasingly popular in recent years,denote the material's feature and state,respectively.The goal of this article is to determine how circularity,criticality,and neutrality are related.Upscale anthropogenic circularity has the potential to expand the metal supply and,as a result,reduce metal criticality.China barely accomplished 15%of its potential emission reduction by recycling iron,copper,and aluminum.Anthropogenic circularity has a lot of room to achieve a win-win objective,which is to reduce metal criticality while also achieving carbon neutrality in a near closed-loop cycle.Major barriers or challenges for conducting anthropogenic circularity are deriving from the inadequacy of life-cycle insight governance and the emergence of anthropogenic circularity discipline.Material flow analysis and life cycle assessment are the central methodologies to identify the hidden problems.Mineral processing and smelting,as well as end-of-life management,are indicated as critical priority areas for enhancing anthropogenic circularity.
文摘Alzheimer's disease,a progressively degenerative neurological disorder,is the most common cause of dementia in the elderly.While its precise etiology remains unclear,researchers have identified diverse pathological characteristics and molecular pathways associated with its progression.Advances in scientific research have increasingly highlighted the crucial role of non-coding RNAs in the progression of Alzheimer's disease.These non-coding RNAs regulate several biological processes critical to the advancement of the disease,offering promising potential as therapeutic targets and diagnostic biomarkers.Therefore,this review aims to investigate the underlying mechanisms of Alzheimer's disease onset,with a particular focus on microRNAs,long non-coding RNAs,and circular RNAs associated with the disease.The review elucidates the potential pathogenic processes of Alzheimer's disease and provides a detailed description of the synthesis mechanisms of the three aforementioned non-coding RNAs.It comprehensively summarizes the various non-coding RNAs that have been identified to play key regulatory roles in Alzheimer's disease,as well as how these noncoding RNAs influence the disease's progression by regulating gene expression and protein functions.For example,miR-9 targets the UBE4B gene,promoting autophagy-mediated degradation of Tau protein,thereby reducing Tau accumulation and delaying Alzheimer's disease progression.Conversely,the long non-coding RNA BACE1-AS stabilizes BACE1 mRNA,promoting the generation of amyloid-βand accelerating Alzheimer's disease development.Additionally,circular RNAs play significant roles in regulating neuroinflammatory responses.By integrating insights from these regulatory mechanisms,there is potential to discover new therapeutic targets and potential biomarkers for early detection and management of Alzheimer's disease.This review aims to enhance the understanding of the relationship between Alzheimer's disease and non-coding RNAs,potentially paving the way for early detection and novel treatment strategies.
基金The authors acknowledge the financial support of the Natural Science and Engineering Research Council of Canada(NSERC)via their CREATE and Discovery Grant programs.
文摘Sphericity,a measure of how much a particle’s shape deviates from spherical,is useful as a shape factorwhen characterizing particulate materials.However,particle surface areas,required when determiningthe sphericity,are very difficult to measure.As a result,the circularity,derivable from microscopic views,is often measured instead and assumed to be equal to the sphericity.This paper shows that the twoquantities are generally not equal for simple non-spherical shapes and provides advice on improving theestimation of sphericity from circularity.
基金supported by the National Natural Science Foundation of China,Nos.82171344(to ZY),82471313(to CKT)the Guangdong Basic and Applied Basic Research Foundation,China,Nos.2023B1515120035,2024A1515012035(to CKT)The Science and Technology Projects in Guangzhou Nos.2025A03J4169(to ZY)。
文摘Stroke-induced alterations in cerebral blood flow trigger neurovascular remodeling,as manifested by the blood-brain barrier dysfunction and subs equent neurovascular repair activities such as angiogenesis.This process involves neurovascular communication that facilitates the transport of mediators among cerebrovascular endothelial cells,pericytes,glial cells,and neurons,thereby transmitting signals from donor to recipient cells to elicit a collaborative response.
基金The final revision of this paper was Garried out within the Gircular Kitchen 2.0 project founded by Vastra Gotalandsregionen(project number:20232029)and Formas-A Swedish Research Council for Sustainable Development(project number:202102454).
文摘This paper aims to contribute to the development of spatial criteria for adaptive capacity,which is identified as one important factor for the transition towards more circular housing design.The paper focuses on the kitchen,as an important function of the home which is connected to large resource flows and is exposed to frequent renovations and replacements.This paper identifies spatial characteristics of the kitchen and evaluates their potential to accommodate circular solutions focusing on adaptive capacity.As a first step,previous literature on the spatial characteristics of kitchens and indicators that support adaptability is reviewed.These are then used to develop an analytical framework to assess the adaptive capacity and circularity potential of 3624 kitchens in contemporary Swedish apartments.A qualitative approach in combination with quantitative methods is employed to analyse the selected sample.The main contributions of this paper include its spatial analytical framework,its descriptive presentation of contemporary kitchen and apartment designs,and its adaptive capacity assessment of the studied kitchens.The results point out that although the overcapacity of the floor area of kitchens and apartments can have significance for adaptability,it is not the only determinative spatial characteristics.The windows’location and distribution,the number of door openings and traffic zones,the shafts’location and accessibility from multiple rooms,the room typology and the kitchen typology can improve the adaptive capacity and circularity potential of kitchens and dwellings.The findings show that in contemporary floorplans advantageous design solutions connected to the identified spatial characteristics are not applied in a systematic way.Further research is necessary to define the exact measures of the individual spatial characteristics and their combined application in multiresidential floorplan design.
文摘Several factors overlap in making urban heritage conservation vulnerable in terms of long-term sustainability.The purpose of this study is to offer insights into the dynamic role that heritage governance plays in the current sustainability debate.This purpose is achieved by investigating the shift from a‘governing for culture’approach to a‘governing through culture’approach in heritage conservation.Subsequently,a case is built for a circularity-based conservation strategy applicable to the governance of historic cities.Different indicators of the circular governance approach are considered,and useful data are collected in comparative form.The cross-matching relationship between the factors is then evaluated by employing the analytic hierarchy process(AHP)on the collected data.As a test case,the conservation strategy of the Medina of Tunis is presented.For a more general conservation model,case-specific data are acquired.Finally,the same framework is applied to compare the case-dependent and case-independent data to define an integrated conservation framework.The obtained results show that the knowledge and data exchange factor,carries the highest significance.This result translates into heritage-led urban regeneration through knowledge sharing and the effective redistribution of cultural activities in historic city centres.
基金supported by the National Natural Science Foundation of China,Nos.82301486(to SL)and 82071325(to FY)Medjaden Academy&Research Foundation for Young Scientists,No.MJR202310040(to SL)+2 种基金Nanjing Medical University Science and Technique Development,No.NMUB20220060(to SL)Medical Scientific Research Project of Jiangsu Commission of Health,No.ZDA2020019(to JZ)Health China Buchang Zhiyuan Public Welfare Project for Heart and Brain Health,No.HIGHER202102(to QD).
文摘Acute ischemic stroke is a clinical emergency and a condition with high morbidity,mortality,and disability.Accurate predictive,diagnostic,and prognostic biomarkers and effective therapeutic targets for acute ischemic stroke remain undetermined.With innovations in high-throughput gene sequencing analysis,many aberrantly expressed non-coding RNAs(ncRNAs)in the brain and peripheral blood after acute ischemic stroke have been found in clinical samples and experimental models.Differentially expressed ncRNAs in the post-stroke brain were demonstrated to play vital roles in pathological processes,leading to neuroprotection or deterioration,thus ncRNAs can serve as therapeutic targets in acute ischemic stroke.Moreover,distinctly expressed ncRNAs in the peripheral blood can be used as biomarkers for acute ischemic stroke prediction,diagnosis,and prognosis.In particular,ncRNAs in peripheral immune cells were recently shown to be involved in the peripheral and brain immune response after acute ischemic stroke.In this review,we consolidate the latest progress of research into the roles of ncRNAs(microRNAs,long ncRNAs,and circular RNAs)in the pathological processes of acute ischemic stroke–induced brain damage,as well as the potential of these ncRNAs to act as biomarkers for acute ischemic stroke prediction,diagnosis,and prognosis.Findings from this review will provide novel ideas for the clinical application of ncRNAs in acute ischemic stroke.
基金National Natural Science Foundation of China(Nos.52174269,52374293)Science and Technology Innovation Program of Hunan Province,China(Nos.2024CK1009,2022RC1123)。
文摘A tunable oxidization and reduction strategy was proposed to directly regenerate spent LiFePO_(4)/C cathode materials by oxidizing excessive carbon powders with the addition of FePO_(4).Experimental results indicate that spent LiFePO_(4)/C cathode materials with good performance can be regenerated by roasting at 650℃ for 11 h with the addition ofLi_(2)CO_(3),FePO_(4),V_(2)O_(5),and glucose.V_(2)O_(5) is added to improve the cycle performance of regenerated cathode materials.Glucose is used to revitalize the carbon layers on the surface of spent LiFePO_(4)/C particles for improving their conductivity.The regenerated V-doped LiFePO_(4)/C shows an excellent electrochemical performance with the discharge specific capacity of 161.36 mA·h/g at 0.2C,under which the capacity retention is 97.85%after 100 cycles.
基金financially supported by the National Natural Science Foundation of China(No.52204310)the Guizhou Provincial Key Laboratory of Coal Clean Utilization(No.[2020]2001)+5 种基金the China Postdoctoral Science Foundation(Nos.2020TQ0059 and 2020M570967)the Natural Science Foundation of Liaoning Province(No.2021–MS–083)the Fundamental Research Funds for the Central Universities,China(No.N2125010)the Open Project Program of Key Laboratory of Metallurgical Emission Reduction&Resources Recycling(Anhui University of Technology),Ministry of Education(No.JKF22–02)the Foundation of Liupanshui Normal University(No.LPSSYZDZK202205)the Key Laboratory for Anisotropy and Texture of Materials,Ministry of Education,China。
文摘With the continuous increase in the disposal volume of spent lithium-ion batteries(LIBs),properly recycling spent LIBs has become essential for the advancement of the circular economy.This study presents a systematic analysis of the chlorination roasting kinetics and proposes a new two-step chlorination roasting process that integrates thermodynamics for the recycling of LIB cathode materials.The activation energy for the chloride reaction was 88.41 kJ/mol according to thermogravimetric analysis–derivative thermogravimetry data obtained by using model-free,model-fitting,and Z(α)function(αis conversion rate).Results indicated that the reaction was dominated by the first-order(F1)model when the conversion rate was less than or equal to 0.5 and shifted to the second-order(F2)model when the conversion rate exceeded 0.5.Optimal conditions were determined by thoroughly investigating the effects of roasting temperature,roasting time,and the mass ratio of NH_(4)Cl to LiCoO_(2).Under the optimal conditions,namely 400℃,20 min,and NH_(4)Cl/LiCoO_(2)mass ratio of 3:1,the leaching efficiency of Li and Co reached 99.43% and 99.05%,respectively.Analysis of the roasted products revealed that valuable metals in LiCoO_(2)transformed into CoCl_(2) and LiCl.Furthermore,the reaction mechanism was elucidated,providing insights for the establishment of a novel low-temperature chlorination roasting technology based on a crystal structure perspective.This technology can guide the development of LIB recycling processes with low energy consumption,low secondary pollution,high recovery efficiency,and high added value.
文摘Multiple functional metasurfaces with high information capacity have attracted considerable attention from researchers.This study proposes a 2-bit tunable spin-decoupled coded metasurface designed for the terahertz band,which utilizes the tunable properties of Dirac semimetals(DSM)to create a novel multilayer structure.By incorporating both geometric and propagating phases into the metasurface design,we can effectively control the electromagnetic wave.When the Fermi level(EF)of the DSM is set at 6 meV,the electromagnetic wave is manipulated by the gold patch embedded in the DSM film,operating at a frequency of 1.3 THz.When the EF of the DSM is set at 80 meV,the electromagnetic wave is manipulated by the DSM patch,operating at a frequency of 1.4 THz.Both modes enable independent control of beam splitting under left-rotating circularly polarized(LCP)and rightrotating circularly polarized(RCP)wave excitation,resulting in the generation of vortex beams with distinct orbital angular momentum(OAM)modes.The findings of this study hold significant potential for enhancing information capacity and polarization multiplexing techniques in wireless communications.
文摘The development of sustainable sludge management systems requires looking at them with a new vision in which the concepts of SD(Sustainable Development)must integrate those of CE(Circular Economy),both concepts subject to the principles of TD(Thermodynamics),thus allowing the adoption of actions that are all the more effective the more complete the evaluation of the social dimension has been.This involves a new“Way of thinking”which sees the sludge system as the“Locomotive”of the entire wastewater/sludge treatment train and is developed through“Ways of acting”which includes both“Technical”actions to maximize recoveries of useful materials and/or or energy,and“Socio/Institutional”actions to overcome barriers linked to local cultures and traditions,also considering that the specific local context heavily influences the choices capable of satisfying the concepts of CE.It follows the need of issuing realistic and applicable regulations and overcoming social barriers,such as lack of infrastructure and/or qualified personnel,to achieve an effective integration of the concepts of CE with the more general ones of sustainability.
