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Constructing multiple sites porous organic polymers for highly efficient and reversible adsorption of triiodide ion from water
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作者 Zhiyong Li Yibo Fu +4 位作者 Yilong Li Ruipeng Li Yuanchao Pei Yunlei Shi Huiyong Wang 《Green Energy & Environment》 2025年第8期1807-1818,共12页
The utilization of nuclear power will persist as a prominent energy source in the foreseeable future.However,it presents substantial challenges concerning waste disposal and the potential emission of untreated radioac... The utilization of nuclear power will persist as a prominent energy source in the foreseeable future.However,it presents substantial challenges concerning waste disposal and the potential emission of untreated radioactive substances,such as radioactive 129I and 131I.The transportation of radioactive iodine poses a significant threat to both the environment and human health.Nevertheless,effectively,rapidly removing iodine ion from water using porous adsorbents remains a crucial challenge.In this work,three kinds of multiple sites porous organic polymers(POPs,POP-1,POP-2,and POP-3)have been developed using a monomer pre-modification strategy for highly efficient and fast I_(3) absorption from water.It is found that the POPs exhibited exceptional performance in terms of I3 adsorption,achieving a top-performing adsorption capacity of 5.25 g g^(-1) and the fastest average adsorption rate(K_(80%)=4.25 g g^(-1) h^(-1))with POP-1.Moreover,POP-1 exhibited exceptional capacity for the removal of I3 fromflowing aqueous solutions,with 95%removal efficiency observed even at 0.0005 mol L^(-1).Such results indicate that this material has the potential to be utilized for the emergency preparation of potable water in areas contaminated with radioactive iodine.The adsorption process can be effectively characterized by the Freundlich model and the pseudo-second-order model.The exceptional I_(3) absorption capacity is primarily attributed to the incorporation of a substantial number of active adsorption sites,including bromine,carbonyl,and amide groups. 展开更多
关键词 Triiodide ion Porous organic polymer Efficient adsorption Multiple site Interaction
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High-temperature thin-film strain sensors with low temperature coefficient of resistance and high sensitivity via direct ink writing
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作者 Lida Xu Fuxin Zhao +10 位作者 Xiong Zhou Yusen Wang Tingting Shen Jun Liu Haidong Wang Guo Yi Xingguang Zhou Chao Wu Yang Zhao Daoheng Sun Qinnan Chen 《Nanotechnology and Precision Engineering》 2025年第1期1-9,共9页
High-temperature thin-film strain sensors are advanced technological devices for monitoring stress and strain in extreme environments,but the coupling of temperature and strain at high temperature is a challenge for t... High-temperature thin-film strain sensors are advanced technological devices for monitoring stress and strain in extreme environments,but the coupling of temperature and strain at high temperature is a challenge for their use.Here,this issue is addressed by creating a composite ink that combines Pb_(2)Ru_(2)O_(6) and TiB_(2) using polysilazane(PSZ)as a binder.After direct writing and annealing the PSZ/Pb_(2)Ru_(2)O_(6)/TiB_(2) film at 800℃ in air,the resulting thin film exhibits a low temperature coefficient of resistance(TCR)of only 281 ppm/℃ over a wide temperature range from 100℃ to 700℃,while also demonstrating high sensitivity with a gauge factor approaching 19.8.This exceptional performance is attributed to the intrinsic properties of Pb_(2)Ru_(2)O_(6),which has positive TCR at high temperature,and TiB2,which has negative TCR at high temperature.Combining these materials reduces the overall TCR of the film.Tests showed that the PSZ/Pb_(2)Ru_(2)O_(6)/TiB_(2) film maintains stable strain responses and significant signal output even under varying temperature.These findings provide valuable insights for developing high-temperature strain sensors with low TCR and high sensitivity,highlighting their potential for applications in high-temperature strain measurements. 展开更多
关键词 High-temperature thinfilm Strain sensor Direct ink writing Low temperature coefficient of resistance High sensitivity
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Energy Efficient MAC Protocol for Wireless Full-Duplex Networks 被引量:2
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作者 Yu Song Wangdong Qi Wenchi Cheng 《China Communications》 SCIE CSCD 2018年第1期35-44,共10页
The wireless full-duplex(FD) nodes can transmit and receive at the same time using the same frequency-band. Currently, the latest FD media access control(MAC) protocols mainly focus on how to convert the physical laye... The wireless full-duplex(FD) nodes can transmit and receive at the same time using the same frequency-band. Currently, the latest FD media access control(MAC) protocols mainly focus on how to convert the physical layer gains of FD nodes to the throughput gain of wireless FD networks, but pay little attention to the energy consumptions of FD nodes. In this paper, we propose an energy efficient FD MAC protocol. According to the values of self-interference cancellation coefficients corresponding to the nodes of each FD pair and the signal propagation attenuation, the proposed protocol can adaptively select the communication mode of the FD pair between the full-duplex and half-duplex. Also, the minimum transmit power for FD nodes can be obtained to achieve high energy efficiency. We develop an analytical model to characterize the performance of our protocol. The numerical results show that the proposed MAC protocol can optimize the system throughput and reduce the transmission energy consumptions of nodes simultaneously as compared with those of the existing works. 展开更多
关键词 wireless full-duplex networks MAC protocol energy efficient self-interference cancellation coefficient
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Rate Coefficients and Branching Ratio for Multi-Channel Hydrogen Abstractions from CH3OH by F 被引量:1
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作者 Dan-dan Lu Chang-jian Xie +1 位作者 Jun Li Hua Guo 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 2019年第1期84-88,I0002,共6页
The hydrogen abstraction reaction F+CH3OH has two possible reaction pathways: HF+CH3O and HF+CH2OH. Despite the absence of intrinsic barriers for both channels, the former has a branching ratio comparable to the latte... The hydrogen abstraction reaction F+CH3OH has two possible reaction pathways: HF+CH3O and HF+CH2OH. Despite the absence of intrinsic barriers for both channels, the former has a branching ratio comparable to the latter, which is far from the statistical limit of 0.25 (one out of four available H atoms). Furthermore, the measured branching ratio of the two abstraction channels spans a large range and is not quantitatively reproduced by previous theoretical predictions based on the transition-state theory with the stationary point information calculated at the levels of MФller-Plesset perturbation theory and G2. This work reports a theoretical investigation on the kinetics and the associated branching ratio of the two competing channels of the title reaction using a quasi-classical trajectory approach on an accurate full-dimensional potential energy surface (PES) fitted by the permutation invariant polynomial-neural network approach to ca. 1.21x10^5 points calculated at the explicitly correlated (F12a) version of coupled cluster singles doubles and perturbative triples (CCSD(T)) level with the aug-cc-pVDZ basis set. The calculated room temperature rate coeffcient and branching ratio of the HF+CH3O channel are in good agreement with the available experimental data. Furthermore, our theory predicts that rate coeffcients have a slightly negative temperature dependence, consistent with barrierless nature of the reaction. 展开更多
关键词 Reaction dynamics Rate coe cient Product branching ratio
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PREPATATION OF SPODUMENE-DERIVED LOW EXPANSION COEFFICIENT GLASS CERAMIC IN THE SYSTEM Li_2O-Al_2O_3-SiO_2 被引量:1
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作者 袁坚 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS 1997年第4期18-24,共7页
In this paper ,spodumene mineral was used as raw material for fabricating glass ceramic with the addition of MgO,ZnO and TiO2,ZrO2. The expansion coefficient of the materials is 5. 5×107/℃ . Also the effects of ... In this paper ,spodumene mineral was used as raw material for fabricating glass ceramic with the addition of MgO,ZnO and TiO2,ZrO2. The expansion coefficient of the materials is 5. 5×107/℃ . Also the effects of the heat treatment on the crystallzing behaviour has been discussed by XRD and DTA. 展开更多
关键词 GLASS-CERAMIC low expansion coeffi-cient spodumene mineral
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Coefficient of Engine Flexibility as a Basis for the Assessment of Vehicle Tractive Performance
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作者 Dariusz Szpica 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2019年第3期189-197,共9页
The paper attempts to analyze full load characteristics of over 500 combustion engines. Using statistical tools, the author determined the value of the coe cient of flexibility. Engine flexibility is the capability of... The paper attempts to analyze full load characteristics of over 500 combustion engines. Using statistical tools, the author determined the value of the coe cient of flexibility. Engine flexibility is the capability of the engine to adapt to varying loads. Importantly, in the investigations, the author took into account the parameters calculated in the course of the investigations on a chassis dynamometer, i.e., actual, not taken from technical specifications of brand new vehicles. Di erent stages of operating wear allow a better characterization of the population. Subsequent utilization of the results in tractive calculations is more reliable. The engines were divided into in six groups, depending on the type of fuel system: fuel injected gasoline and turbocharged gasoline, spark ignition LPG, naturally aspirated diesel and turbocharged diesel. However, engines running on alternative fuels are characterized with a greater flexibility than the fuel injected base engines. Conformity of flexibility of fuel injected and LPG IV generation engines have been observed,which confirms the appropriateness of engine adaptation to alternative fueling. Gasoline engine supercharging allowed a reduction of the maximum engine speed of the maximum torque, which extends the range of analyzable speeds for flexibility and consequently, the flexibility as such. 展开更多
关键词 VEHICLE Tractive performance Flexibility coe cient Engine characteristics
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Energy-Efficient Routing Protocol with Multi-Hop Fuzzy Logic for Wireless Networks
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作者 J.Gobinath S.Hemajothi J.S.Leena Jasmine 《Intelligent Automation & Soft Computing》 SCIE 2023年第5期2457-2471,共15页
A Wireless Sensor Network(WSN)becomes a newer type of real-time embedded device that can be utilized for a wide range of applications that make regular networking which appears impracticable.Concerning the energy prod... A Wireless Sensor Network(WSN)becomes a newer type of real-time embedded device that can be utilized for a wide range of applications that make regular networking which appears impracticable.Concerning the energy produc-tion of the nodes,WSN has major issues that may influence the stability of the system.As a result,constructing WSN requires devising protocols and standards that make the most use of constrained capacity,especially the energy resources.WSN faces some issues with increased power utilization and an on going devel-opment due to the uneven energy usage between the nodes.Clustering has proven to be a more effective strategy in this series.In the proposed work,a hybrid meth-od is used for reducing the energy consumption among CHs.A Fuzzy Logic-based clustering protocol FLUC(unequally clustered)and Fuzzy Clustering with Energy-Efficient Routing Protocol(FCERP)are used.A Fuzzy Clustering with Energy Efficient Routing Protocol(FCERP)reduces the WSN power usage and increases the lifespan of the network.FCERP has created a novel cluster-based fuzzy routing mechanism that uses a limit value to combine the clustering and multi-hop routing capabilities.The technique creates uneven groups by using fuz-zy logic with a competitive range to choose the Cluster Head(CH).The input variables include the distance of the nodes from the ground station,concentra-tions,and remaining energy.The proposed FLUC-FCERP reduces the power usage and improves the lifetime of the network compared with the existing algorithms. 展开更多
关键词 Energy consumption LIFETIME wireless sensor network cluster head fuzzy logic unequally clustered fuzzy clustering energy-efficient protocol
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Cluster Head Selection and Multipath Routing Based Energy Efficient Wireless Sensor Network
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作者 T.Shanmugapriya Dr.K.Kousalya 《Intelligent Automation & Soft Computing》 SCIE 2023年第4期879-894,共16页
The Wireless Sensor Network(WSN)is a network of Sensor Nodes(SN)which adopt radio signals for communication amongst themselves.There is an increase in the prominence of WSN adaptability to emerging applications like t... The Wireless Sensor Network(WSN)is a network of Sensor Nodes(SN)which adopt radio signals for communication amongst themselves.There is an increase in the prominence of WSN adaptability to emerging applications like the Internet of Things(IoT)and Cyber-Physical Systems(CPS).Data secur-ity,detection of faults,management of energy,collection and distribution of data,network protocol,network coverage,mobility of nodes,and network heterogene-ity are some of the issues confronted by WSNs.There is not much published information on issues related to node mobility and management of energy at the time of aggregation of data.Towards the goal of boosting the mobility-based WSNs’network performance and energy,data aggregation protocols such as the presently-used Mobility Low-Energy Adaptive Clustering Hierarchy(LEACH-M)and Energy Efficient Heterogeneous Clustered(EEHC)scheme have been exam-ined in this work.A novel Artificial Bee Colony(ABC)algorithm is proposed in this work for effective election of CHs and multipath routing in WSNs so as to enable effective data transfer to the Base Station(BS)with least energy utilization.There is avoidance of the local optima problem at the time of solution space search in this proposed technique.Experimentations have been conducted on a large WSN network that has issues with mobility of nodes. 展开更多
关键词 Wireless sensor network ROUTING clustering MOBILITY low-energy adaptive clustering hierarchy energy efficient heterogeneous clustered artificial bee colony
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8种水产药物对膨腹海马幼苗急性毒性试验及安全评价
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作者 黄春芳 卓玉琛 +4 位作者 林煜 翁可佳 樊海平 甘琦峰 林而舒 《渔业研究》 2026年第2期264-274,共11页
【目的】获得强氯精、甲醛、硫酸铜、过氧化氢、硫酸锌、甲霜灵、苯扎溴铵和氯硝柳胺8种水产养殖常用渔药对膨腹海马的安全质量浓度(SC),为膨腹海马的繁育、养殖生产用药和病害防控提供理论依据。【方法】在水温16~18℃条件下,以平均体... 【目的】获得强氯精、甲醛、硫酸铜、过氧化氢、硫酸锌、甲霜灵、苯扎溴铵和氯硝柳胺8种水产养殖常用渔药对膨腹海马的安全质量浓度(SC),为膨腹海马的繁育、养殖生产用药和病害防控提供理论依据。【方法】在水温16~18℃条件下,以平均体长4~6cm、平均体质量(1.83±0.26)g的膨腹海马幼苗为试验对象,采用半静态换水补药的方法测定8种渔药制剂对膨腹海马幼苗的急性毒性,通过药物毒性蓄积系数(MAC)分析药物对膨腹海马幼苗的急性致毒效应特征。【结果】8种渔药对膨腹海马幼苗的MAC均为正值,SC从高到低分别为甲醛(24.858 mg/L)、过氧化氢(19.498 mg/L)、强氯精(1.481 mg/L)、甲霜灵(0.369 mg/L)、硫酸铜(0.339 mg/L)、苯扎溴铵(0.247 mg/L)、硫酸锌(0.185 mg/L)、氯硝柳胺(0.024 mg/L)。【结论】8种药物的蓄积作用强于降减作用,其中强氯精、甲醛、过氧化氢对膨腹海马幼苗的毒性等级为低毒;硫酸铜、硫酸锌、甲霜灵和苯扎溴铵为中毒;氯硝柳胺为高毒。 展开更多
关键词 膨腹海马 急性毒性 安全质量浓度(SC) 药物毒性蓄积系数(MAC) 安全性评价
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一种改进型光储虚拟同步发电机的自适应控制策略
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作者 田甜 郭翔宇 《机械工程师》 2026年第4期45-48,共4页
为了解决微电网虚拟同步发电机的功频振荡问题,提出了一种改进型自适应控制策略。首先依据转子运动状态方程推导了有功功率二阶传递函数,采用根轨迹法分析了转动惯量J和阻尼系数D对系统稳定性的影响;其次,根据频率上升和恢复两个方面对... 为了解决微电网虚拟同步发电机的功频振荡问题,提出了一种改进型自适应控制策略。首先依据转子运动状态方程推导了有功功率二阶传递函数,采用根轨迹法分析了转动惯量J和阻尼系数D对系统稳定性的影响;其次,根据频率上升和恢复两个方面对传统指数型自适应函数进行分段改进设计。改进型自适应控制在抑制频率上升的基础上增加了频率快速恢复功能,通过分段式自适应函数实现频率上升抑制和频率加速恢复的双重效果,使系统稳定性大幅度提升。最后,通过搭建时域仿真模型验证了所提控制策略的有效性。 展开更多
关键词 虚拟同步发电机 自适应控制策略 转动惯量 阻尼系数 光储系统
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考虑受力特性的钢板剪力墙施工技术研究
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作者 潘俊 《建筑技术》 2026年第6期728-732,共5页
针对钢板剪力墙结构在高层建筑中的广泛应用,本研究基于其受力特性,系统分析了施工过程中的关键技术难点,提出了一套优化施工工艺。利用ABAQUS软件建立钢板剪力墙有限元模型,分析剪力墙内钢板隔板贯通焊接、穿芯螺栓、悬臂段-端板3种连... 针对钢板剪力墙结构在高层建筑中的广泛应用,本研究基于其受力特性,系统分析了施工过程中的关键技术难点,提出了一套优化施工工艺。利用ABAQUS软件建立钢板剪力墙有限元模型,分析剪力墙内钢板隔板贯通焊接、穿芯螺栓、悬臂段-端板3种连接方式下的塑性和正负方向振动弹性受力性能。从塑性应变、承载能力、弹性应变等方面,进行了钢板剪力墙的受力特性分析。根据分析结果优化钢板剪力墙施工方案,为施工安全性的提升提供依据,为同类工程提供了可借鉴的技术方案。 展开更多
关键词 受力特性 钢板剪力墙 有限元模型 塑性应变 承载能力 延性系数
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省域数字经济与高职教育耦合协调性的量化评价
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作者 王敏 张海生 《教育学术月刊》 北大核心 2025年第10期59-66,共8页
数字经济是新一轮科技革命的主要经济业态,而高职教育肩负着培养技能型人才的重要使命,二者存在共生共荣的关系。基于2015-2022年我国30个省域的面板数据,采用耦合协调度模型、Dagum基尼系数、空间杜宾模型对省域数字经济与高职教育耦... 数字经济是新一轮科技革命的主要经济业态,而高职教育肩负着培养技能型人才的重要使命,二者存在共生共荣的关系。基于2015-2022年我国30个省域的面板数据,采用耦合协调度模型、Dagum基尼系数、空间杜宾模型对省域数字经济与高职教育耦合协调度发展水平、时空特征、区域差异以及影响因素进行分析。研究结果表明:(1)研究期内,各省域耦合协调度呈波动上升趋势,且呈现明显的地域差异,对基尼系数分解发现其差异主要由区域间差异主导。(2)耦合协调度的空间正相关性逐渐增强,局部集聚形态从"高—高""低—高"向"高—高""低—低"转变。(3)空间计量模型结果显示,地区人口受教育程度、政府对高职支持程度对本地耦合协调度具有显著正向作用,对外开放程度、政府对市场干预程度、产业结构、高职依赖度等存在明显的空间溢出效应,除对外开放程度外,均呈现正向效应。为推动数字经济与高职教育的协调发展,应加大数字产业人才培养力度,建立产教匹配机制;加强区域统筹协调,同时发挥区域内"领头羊"的带头作用;发挥政府和市场各自的作用,以"有为政府"和"有效市场"支持和引导二者的耦合协调发展。 展开更多
关键词 数字经济 高等职业教育 耦合协调度 Dagum基尼系数 空间计量
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超声疲劳系统动力学分析及试验应力修正
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作者 邓彩艳 李琦 +1 位作者 龚宝明 宋宗贤 《天津大学学报(自然科学与工程技术版)》 北大核心 2025年第6期583-590,共8页
超声疲劳试验可快速获得材料在超高周寿命区间的疲劳性能.试验应力计算是超高周疲劳试验的关键内容,其决定了试验数据的准确性,但目前研究人员在计算试验应力时均未考虑超声变幅杆和试样的耦合作用.针对这一问题,本文采用数值模拟方法... 超声疲劳试验可快速获得材料在超高周寿命区间的疲劳性能.试验应力计算是超高周疲劳试验的关键内容,其决定了试验数据的准确性,但目前研究人员在计算试验应力时均未考虑超声变幅杆和试样的耦合作用.针对这一问题,本文采用数值模拟方法对超声变幅杆和试样进行了动力学分析,并对超声变幅杆和试样的端部振幅进行了测量.结果表明:考虑超声变幅杆和试样耦合作用得到的振幅与试验测量结果误差最大仅为5.4%,而传统解析法的误差可达25.5%;进一步对比发现材料阻尼对共振频率的影响较大,而外加静态载荷对超声疲劳系统的动力学行为的影响可以忽略;本文中以EH690钢试验获得的S-N曲线为例进行了应力修正,发现经整体法修正后的疲劳应力要高于解析法确定的应力水平. 展开更多
关键词 超声疲劳系统 有限元分析 放大系数 应力位移系数 S-N曲线
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Life-Cycle Bearing Capacity for Pre-Stressed T-beams Based on Full-Scale Destructive Test
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作者 Yushan Ye Tao Gao +4 位作者 Liankun Wang Junjie Ma Yingchun Cai Heng Liu Xiaoge Liu 《Structural Durability & Health Monitoring》 EI 2025年第1期145-166,共22页
To investigate the evolution of load-bearing characteristics of pre-stressed beams throughout their service life and to provide a basis for accurately assessing the actual working state of damaged pre-stressed concret... To investigate the evolution of load-bearing characteristics of pre-stressed beams throughout their service life and to provide a basis for accurately assessing the actual working state of damaged pre-stressed concrete T-beams,destructive tests were conducted on full-scale pre-stressed concrete beams.Based on the measurement and ana-lysis of beam deflection,strain,and crack development under various loading levels during the research tests,combined with the verification coefficient indicators specified in the codes,the verification coefficients of bridges at different stages of damage can be examined.The results indicate that the T-beams experience complete,incom-plete linear,and non-linear stages during the destructive test process.In the complete linear elastic stage,both the deflection and bottom strain verification coefficients comply with the specifications,indicating a good structural load-bearing capacity no longer adheres to the code’s requirements.In the non-linear stage,both coefficients exhi-bit a sharp increase,resulting in a further decrease in the structure’s load-bearing capacity.According to the pro-visions of the current code,the beam can be in the incomplete linear stage when both values fall within the code’s specified range.The strain verification coefficient sourced from the compression zone at the bottom of theflange is not recommended for assessing the bridge’s load-bearing capacity. 展开更多
关键词 Pre-stressed T-beams whole process destructive test bearing capacity verification coefficient
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Simulated and experimental study of the chip deformation mechanisms of monocrystalline Cu
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作者 Bing Liu Kai Jiang +4 位作者 Yuxiang Chen Haijie Yang Yurong Wang Keyu Sun Haiyang Li 《Nanotechnology and Precision Engineering》 2025年第1期68-78,共11页
Monocrystalline Cu exhibits excellent electrical and signal-transmission properties due to its absence of grain boundaries,making it a critical material for the production of micro-machinery and micro-components;howev... Monocrystalline Cu exhibits excellent electrical and signal-transmission properties due to its absence of grain boundaries,making it a critical material for the production of micro-machinery and micro-components;however,achieving ultrahigh precision and ultralow damage machining of functional devices using traditional techniques such as grinding and polishing is extremely challenging.Consequently,nanocutting has emerged as an efficient means to fabricate monocrystalline materials with complex surface characteristics and high surface integrity.Nevertheless,the macroscopic cutting theory of metal materials cannot be applied to nanocutting.Accordingly,in this paper,both simulations and experiments were conducted to examine the chip deformation mechanisms of monocrystalline Cu.First,large-scale molecular dynamics(MD)simulations were conducted to gain a comprehensive understanding of the deformation behavior during nanocutting.This included examining the influencing factors and the variation patterns of the chip deformation coefficient,cutting force,and minimum cutting thickness.Subsequently,nanocutting experiments were performed using a specially designed nanocutting platform with high-resolution online observation by scanning electron microscopy.The experimental results served to verify the accuracy and reliability of theMDmodeling,as they exhibited excellent consistency with the simulated results.Although this work considered monocrystalline Cu,it is believed that the elucidated chip deformation mechanisms could also be applied to other face-centered-cubic metals.These results are of great value for advancing the understanding of the mechanisms of ultraprecision cutting. 展开更多
关键词 Monocrystalline Cu Nanocutting Chip deformation coefficient Cutting force Minimum cutting thickness
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《唐刺史考全编》续补——以《榆阳区古代碑刻艺术博物馆藏志》为中心
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作者 严寅春 《咸阳师范学院学报》 2025年第3期94-102,共9页
利用李浩主编《榆阳区古代碑刻艺术博物馆藏志》所收录新见唐代墓志,为郁贤皓先生《唐刺史考全编(增订本)》进行了增订校补,涉及59个州郡、72任刺史,包括任职年限的进一步考订,赠官的删削以及新见刺史的增补。
关键词 《唐刺史考全编》 《榆阳区古代碑刻艺术博物馆藏志》 唐代刺史 新见墓志
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胸部SMARCA4缺失的未分化肿瘤及SMARCA4缺失的非小细胞癌的临床病理特征分析 被引量:2
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作者 林海峰 穆晶 +3 位作者 孙祖钰 周立娟 刘子臣 车南颖 《中国医刊》 2025年第5期536-540,共5页
目的分析经过病理学确诊的胸部SMARCA4缺失的未分化肿瘤(SMARCA4-UT)及SMARCA4缺失的非小细胞癌(SMARCA4-dNSCLC)患者的临床病理特征及预后。方法选取2023年1月至2024年6月经首都医科大学附属北京胸科医院病理科诊断的倾向低分化癌的高... 目的分析经过病理学确诊的胸部SMARCA4缺失的未分化肿瘤(SMARCA4-UT)及SMARCA4缺失的非小细胞癌(SMARCA4-dNSCLC)患者的临床病理特征及预后。方法选取2023年1月至2024年6月经首都医科大学附属北京胸科医院病理科诊断的倾向低分化癌的高级别肿瘤且SMARCA4/BRG1免疫组织化学染色呈阴性表达的患者35例,回顾性分析其临床资料,包括性别、年龄、吸烟史、免疫组织化学染色结果、下一代测序检测结果、PD-L1表达、临床分期、治疗方案和随访情况。结果35例胸部SMARCA4缺失型肿瘤患者中,男28例(80%),女7例(20%),年龄35~79岁(中位年龄63.6岁);临床分期为Ⅰ期4例(11.43%),Ⅱ期4例(11.43%),Ⅲ期8例(22.86%),Ⅳ期19例(54.28%);最常出现转移的部位包括肺门及纵隔淋巴结、骨、肾上腺、胸腔积液、肺内转移、锁骨上淋巴结、胸膜、心包积液、皮肤,27例患者出现多发转移。SMARCA4-dNSCLC的组织学形态呈现多种低分化非小细胞癌形态;SMARCA4-UT的组织学形态分化较差,并失去了上皮癌的特征;免疫组织化学SMARCA4/BRG1蛋白完全或部分阴性表达。97.14%(34例)的患者Ki-67≥30%,4例患者PD-L1≥75%。在胸部SMARCA4缺失型肿瘤患者中,与SMARCA4突变相关的基因突变包括TP53突变、KRAS突变、MYC突变等。Ⅰ~Ⅱ期的患者以手术治疗为主,术后给予化疗联合免疫治疗;4例Ⅲ期患者应用新辅助治疗降期后进行手术,其中1例患者达到了完全病理缓解;而对于无法手术的Ⅲ期或Ⅳ期患者,需要化疗、免疫治疗联合抗血管生成药物共同使用。9例Ⅳ期患者经治疗后达到部分缓解,5例治疗后进展。有9例Ⅳ期患者放弃下一步治疗,随访1~6个月后均死亡。35例患者中有10例患者给予外科手术切除治疗,随访6个月均无变化。结论将SMARCA4纳入免疫组织化学组套以诊断所有低分化癌的表型的诊断检查将有助于其早期识别。SMARCA4-UT与SMARCA4-dNSCLC均具有独特的临床病理特征,即侵袭性高、进展快、预后差。对于早期患者手术治疗依然是最优选,化疗联合免疫治疗可能有效,还需要长期病例积累观察。 展开更多
关键词 胸部 SMARCA4缺失的未分化肿瘤 肺癌 诊断 预后
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超声黏弹性成像在乳腺肿瘤良恶性鉴别中的研究 被引量:1
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作者 覃雨 李程 +5 位作者 华晴 张慧婷 贾宛儒 董屹婕 周建桥 夏蜀珺 《诊断学理论与实践》 2025年第2期194-203,共10页
目的:探讨超声黏弹性成像技术在乳腺肿瘤良恶性鉴别中的应用价值。方法:连续纳入2023年2月至2023年8月期间,上海交通大学医学院附属瑞金医院收治的经手术病理证实为乳腺肿瘤的717例患者,其中471例为恶性,246例为良性。所有患者均在治疗... 目的:探讨超声黏弹性成像技术在乳腺肿瘤良恶性鉴别中的应用价值。方法:连续纳入2023年2月至2023年8月期间,上海交通大学医学院附属瑞金医院收治的经手术病理证实为乳腺肿瘤的717例患者,其中471例为恶性,246例为良性。所有患者均在治疗前进行乳腺超声检查,包括灰阶超声、超声应变弹性成像、超声剪切波弹性成像、超声黏性成像。超声黏弹性成像技术包括测量肿瘤及其周围组织的黏性系数、频散系数和剪切波弹性模量、应变比等4组参数,以4组参数中的较佳预测指标,分别构建多种预测模型,包括黏性系数单变量模型、频散系数单变量模型、黏性组合模型(Shell/T-Vmean+Shell/T-Dmean)、剪切波单变量模型、应变单变量模型、乳腺影像报告和数据系统(Breast Imaging Reporting and Data System,BI-RADS)、BI-RADS联合黏性组合模型,评估每种模型在乳腺肿瘤良恶性鉴别中的效能。结果:超声黏弹性成像的黏性系数、频散系数、弹性模量及应变比等参数均可有效地区分乳腺良恶性肿瘤,其中肿瘤边缘2 mm区域与瘤体的参数比值Shell/T-Vmean、Shell/T-Dmean、Shell/T-Emean、Strain Ratio A为较佳预测指标,曲线下面积分别为0.742、0.745、0.726、0.705,而BI-RADS模型预测乳腺肿瘤良恶性的0.822。将Shell/T-Vmean、Shell/T-Dmean分别与BI-RADS分类联合时,受试者操作特征曲线的曲线下面积高达0.895(95%CI为0.868~0.917),高于BI-RADS。结论:超声黏弹性成像的黏弹性参数中,肿瘤边缘2 mm区域与瘤体的黏性系数、频散系数及弹性模量均值比为关键诊断指标;Shell/T-Vmean、Shell/T-Dmean联合BI-RADS后,可为术前无创精准诊断提供了新策略。 展开更多
关键词 超声黏弹性成像 乳腺肿瘤 良恶性鉴别 黏性系数 频散系数
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基于权重系数的轨道车辆车体结构多目标拓扑优化研究
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作者 刘佳超 杜彦品 +2 位作者 廖平 朱涛 肖守讷 《现代交通与冶金材料》 2025年第4期51-58,共8页
针对轨道车辆车体结构多目标拓扑优化时权重系数的选择缺乏科学准确性的问题,提出了基于遗传算法优化BP神经网络的最佳权重系数确定方法,有效地提高了优化的精度。建立了车体结构待优化的有限元模型,确定了拓扑优化所需的计算工况,并基... 针对轨道车辆车体结构多目标拓扑优化时权重系数的选择缺乏科学准确性的问题,提出了基于遗传算法优化BP神经网络的最佳权重系数确定方法,有效地提高了优化的精度。建立了车体结构待优化的有限元模型,确定了拓扑优化所需的计算工况,并基于变密度法和平方和加权法以静态刚度和动态频率为目标建立数学模型进行多目标拓扑优化,发现在权重系数确定的问题中,使用遗传算法优化BP神经网络的方法有很高的预测精度,静态刚度和动态频率的预测精度分别达到97.46%和99.68%,相比传统方法更有优势。对车体结构多目标拓扑优化的结果进行分析,得到了载荷的主要传递路径以及材料的最佳分布,为车体轻量化设计提供了指导性意见。 展开更多
关键词 车体结构 轨道车辆 多目标拓扑优化 权重系数 BP神经网络 遗传算法
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基于热值差异的煤炭产品产率补偿系数模型构建
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作者 邓军 曹立洲 +6 位作者 夏树伟 贺国章 杜玉磊 沈澍昊 韩有理 周伟 朱金波 《选煤技术》 2025年第6期61-65,共5页
为解决选煤厂因煤炭产品热值波动导致的产率与销售效益不匹配问题,实现不同热值煤炭产品实际价值的准确评估与合理定价,构建了煤炭产品产率补偿系数模型,通过煤炭热值与灰分的经验关系式反算目标热值对应灰分,结合原煤可选性曲线确定精... 为解决选煤厂因煤炭产品热值波动导致的产率与销售效益不匹配问题,实现不同热值煤炭产品实际价值的准确评估与合理定价,构建了煤炭产品产率补偿系数模型,通过煤炭热值与灰分的经验关系式反算目标热值对应灰分,结合原煤可选性曲线确定精煤产率,引入补偿产率(φ_(20.929)),测算不同热值产品折算至20.929 MJ基准热值时的补偿系数(α);同时以朱集西选煤厂低硫气煤为实例,开展了不同热值产品的补偿方案设计与经济效益测算。结果表明,煤炭产品热值与补偿系数呈正相关关系,18.836~25.115 MJ热值范围内补偿系数变化区间为0.969~1.319,其中20.929 MJ基准热值下补偿系数为1.000,热值低于该基准时α<1,热值高于该基准时α>1;产品热值低于基准时,灰分与实际产率偏高,经补偿系数折算后价值降低,产品热值高于基准时,灰分与实际产率偏低,经补偿系数折算后价值提高。所构建的补偿系数模型可实现不同热值煤炭产品产率的补偿折算,不仅为选煤厂经济效益测算与产品定价提供理论依据,而且可助力选煤厂制定合理的市场销售策略,实现资源合理配置与经济效益最大化。 展开更多
关键词 选煤厂效益核算 煤炭产品产率补偿 补偿系数 补偿产率 热值 灰分 产率
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