To the Editor:Intraductal papillary neoplasm of the bile duct(IPNB)may occur in the setting of primary sclerosing cholangitis,choledochal cysts or hepatolithiasis[1].The entity may be a precursor of cancer or intrahep...To the Editor:Intraductal papillary neoplasm of the bile duct(IPNB)may occur in the setting of primary sclerosing cholangitis,choledochal cysts or hepatolithiasis[1].The entity may be a precursor of cancer or intrahepatic cholangiocarcinoma.Invasive carcinoma,tubular or mucinous adenocarcinoma is present in approximately 40%-80%of IPNBs[1–3].IPNB is frequently found in the resection margins of patients undergoing hepatectomy for cholangiocarcinoma[4].展开更多
BACKGROUND In the last decade, confocal laser endomicroscopy (CLE) has emerged as a newendoscopic imaging modality for real-time in vivo histological examination at themicroscopic level. CLE has been shown to be usefu...BACKGROUND In the last decade, confocal laser endomicroscopy (CLE) has emerged as a newendoscopic imaging modality for real-time in vivo histological examination at themicroscopic level. CLE has been shown to be useful for distinguishing benign andmalignant lesions and has been widely used in many digestive diseases. In ourstudy, we used CLE for the first time to examine the morphology of cholesterolpolyps as well as the different parts of normal gallbladder mucosa.CASE SUMMARY A 57-year-old woman was diagnosed by ultrasound with a polyp of 21 mm in thegallbladder wall. She consented to polyp removal by laparoscopic choledochoscopy.During laparoscopic cholecystectomy combined with choledochoscopicpolyp resection, CLE was used to observe the morphology of the polyp surfacecells. The appearance of the mucosa and microvessels in various parts of thegallbladder were also observed under CLE. Through comparison betweenpostoperative pathology and intraoperative CLE diagnosis, the reliability ofintraoperative CLE diagnosis was confirmed. CLE is a reliable method to examineliving cell pathology during cholecystectomy. Based on our practice, CLE shouldbe prioritized in the diagnosis of gallbladder polyps.CONCLUSION Compared with traditional histological examination, CLE has several advantages.We believe that CLE has great potential in this field.展开更多
Photodynamic therapy(PDT)has emerged as a prominent modality in the therapeutic armamentarium against malignant tumors,particularly those originating from the cutaneous and mucosal tissues(1).The principle of PDT invo...Photodynamic therapy(PDT)has emerged as a prominent modality in the therapeutic armamentarium against malignant tumors,particularly those originating from the cutaneous and mucosal tissues(1).The principle of PDT involves the administration of a photosensitizing agent that selectively accumulates within neoplastic cells(2).Upon exposure to laser light of specific wavelengths,the photosensitizer becomes activated,triggering the generation of reactive oxygen species(ROS)such as oxygen radicals(3).This process culminates in cellular damage and subsequent tumor destruction.PDT holds promise as a localized therapeutic option for unresectable or recurrent cholangiocarcinomas(4).展开更多
BACKGROUND In recent years,the use of ultrafine choledochoscopy has gradually increased in the treatment of cholelithiasis.However,stone incarceration and residual spasm of the sphincter of Oddi may be inevitable when...BACKGROUND In recent years,the use of ultrafine choledochoscopy has gradually increased in the treatment of cholelithiasis.However,stone incarceration and residual spasm of the sphincter of Oddi may be inevitable when an ultrafine choledochoscope is used alone.AIM To investigate the safety and feasibility of ultrafine choledochoscopy combined with low-dose atropine in the treatment of Oddi intersphincter stones.METHODS Seventeen patients with Oddi intersphincter stones were retrospectively analyzed.The perioperative clinical data and follow-up information were collected.RESULTS Among the 17 patients,3 were male and 14 were female.The mean age was 40.6±13.9 years,and the mean diameter of the common bile duct was 7.8±1.3 mm.All patients successfully underwent Oddi intersphincter stone removal using a combination of ultrafine choledochoscopy and low-dose atropine.No serious complications,such as postoperative hemorrhage,pancreatitis or bile leakage occurred in the 17 patients.During the one-year follow-up,none of the patients experienced stone recurrence.CONCLUSION Ultrafine choledochoscopy combined with low-dose atropine is safe and feasible for the treatment of Oddi intersphincter stones.展开更多
Soft fiberoptic choledochoscope is an important tool for the diagnose and surgical treatment of biliary disease.However,the traditional soft fiberoptic choledochoscope is hard to operate,due to the low position accura...Soft fiberoptic choledochoscope is an important tool for the diagnose and surgical treatment of biliary disease.However,the traditional soft fiberoptic choledochoscope is hard to operate,due to the low position accuracy.Based on the conventional soft fiberoptic choledochoscope,an electrical soft fiberoptic choledochoscope robot with a low latency was developed.In order to improve the controllability of the conventional choledochoscope,the wire traction mechanism and the rotation mechanism are used to bend and rotate the scope,so as to control its movement orientation.The dead band compensation model and control algorithm of the wire traction mechanism are developed to improve the accuracy of the orientation control.The human-computer interaction system and complex motion control system are developed based on ARM embedded system and FPGA.Thanks to the high-speed synchronization channel between FPGA and peripheral,the design of low latency whole-procedure surgical mode was established and verified.Combined with a micro image sensor,real-time video back transmission was realized.The performance of the robot prototype was verified by animal experiment in vivo on a pig.The robot has an extremely low operating latency of no more than 0.402 ms,and a high bending positioning accuracy of±1.43°error margin within 99.7%confidence interval,which guarantees the safety of biliary surgery.展开更多
AIM:To introduce and evaluate the new method used in treatment of pancreatic and peripancreatic infections secondary to severe acute pancreatitis(SAP).METHODS:A total of 42 SAP patients initially underwent ultrasound-...AIM:To introduce and evaluate the new method used in treatment of pancreatic and peripancreatic infections secondary to severe acute pancreatitis(SAP).METHODS:A total of 42 SAP patients initially underwent ultrasound-guided percutaneous puncture and catheterization.An 8-Fr drainage catheter was used to drain the infected peripancreatic necrotic foci for 3-5 d.The sinus tract of the drainage catheter was expanded gradually with a skin expander,and the 8-Fr drainage catheter was replaced with a 22-Fr drainage tube after 7-10 d.Choledochoscope-guided debridement was performed repeatedly until the infected peripancreatic tissue was effectively removed through the drainage sinus tract.RESULTS:Among the 42 patients,the infected peripancreatic tissue or abscess was completely removed from 38 patients and elective cyst-jejunum anastomosis was performed in 4 patients due to formation of pancreatic pseudocysts.No death and complication occurred during the procedure.CONCLUSION:Percutaneous catheter drainage in combination with choledochoscope-guided debridement is a simple,safe and reliable treatment procedure for peripancreatic infections secondary to SAP.展开更多
When a distal common bile duct neoplasm is at the stage of carcinoma in situ or high-grade dysplasia,it is difficult for the surgeon to decide whether to perform pancreaticoduodenectomy.Here we describe a patient with...When a distal common bile duct neoplasm is at the stage of carcinoma in situ or high-grade dysplasia,it is difficult for the surgeon to decide whether to perform pancreaticoduodenectomy.Here we describe a patient with a progressive dysplastic lesion in the common bile duct,which developed from moderate-high to highgrade dysplasia in approximately 2 mo.The patient refused major surgery.Therefore,endoscopic-assisted photodynamic therapy was performed.The result at follow-up using a trans-T-tube choledochoscope showed that the lesion was completely necrotic.This report is the first to describe the successful treatment of highgrade dysplasia of the distal bile duct using photodynamic therapy via a choledochoscope.展开更多
AIM： To assess the effects of H2-receptor blocking pharmacon, protease inhibitor, and gastro kinetic agents on the human Sphincter of Oddi （SO） motility by choledochoscope manometry. METHODS： One hundred and seven...AIM： To assess the effects of H2-receptor blocking pharmacon, protease inhibitor, and gastro kinetic agents on the human Sphincter of Oddi （SO） motility by choledochoscope manometry. METHODS： One hundred and seventy-five patients with T tube installed after cholecystectomy and choledochotomy were assessed by choledochoscope manometry. They were randomly assigned into groups of H2-receptor blocking pharmacon, protease inhibitor, and gastro kinetic agents. The Sphincter of Oddi basal pressure （SOBP）, amplitude （SOCA）, frequency of contractions （SOF）, duodenal pressure （DP）, and common bile duct pressure （CBDP） were scored and analyzed. RESULTS： SOBP and SOCA were significantly decreased after Cimetidine administration, and no statistical difference was seen in the Famotidine group. In the Gabexate mesilate group, SOBP had decreased significantly. In the Ulinastatin group, SOCA decreased when Ulinastatin was given at the rate of 2500 U/min; when Ulinastatin administration was raised to 5000 U/ rain, SOBP, SOF and SOCA all experienced a fall. SOBP and SOCA for Domperidone and SOCA for Mosapride groups all decreased distinctly after administration. CONCLUSION： The regular dosage of Cimetidine showed an inhibitory effect on the motility of SO, while Famotidine had no obvious effects otherwise. Gabnexata mesilate, Ulinastatin and gastro kinetic agents also showed inhibitory effects on the SO motility.展开更多
BACKGROUND Endoscopically or fluoroscopically guided dilation is a safe and effective alternative to surgery for patients with benign strictures of the gastric outlet.CASE SUMMARY We describe two cases where a novel a...BACKGROUND Endoscopically or fluoroscopically guided dilation is a safe and effective alternative to surgery for patients with benign strictures of the gastric outlet.CASE SUMMARY We describe two cases where a novel approach with a Spyglass~? choledochoscope in assessing the extent of benign duodenal strictures and aiding in placement of duodenal stents for treatment of the strictures. Choledochoscope-guided wire and stent placement was successful in all cases, leading to symptom resolution related to benign duodenal obstruction. No major adverse events were observed.CONCLUSION Choledochoscope-guided assessment and endoscopic therapy is a viable approach in relieving duodenal obstruction, if the conventional combined fluoroscopic and endoscopic methods fail.展开更多
Objective: To investigate the effect of clinical ursodeoxycholic acid combined with holmium laser by laparoscopic choledochoscopy in the treatment of intrahepatic and intrahepatic bile duct stones. Methods: Patients w...Objective: To investigate the effect of clinical ursodeoxycholic acid combined with holmium laser by laparoscopic choledochoscopy in the treatment of intrahepatic and intrahepatic bile duct stones. Methods: Patients with intrahepatic and intrahepatic bile duct stones treated by surgery in our hospital from October 2017 to December 2018 were randomly divided into control group and observation group.Patients in the control group were treated with laparoscopic choledochoscopy combined with holmium laser lithotripsy, and patients of the observation group were treated with ursodeoxycholic acid on the basis of the control group. The clinical efficacy, total bile acid (TBA), phospholipid (PLIP), cholesterol (CHO) levels and the incidence of complications of liver function and bile related indicators were compared between the two groups after 3 and 6 months treatment. Results: After 3 months treatment, there were 22 cases of cured patients, 11 cases of markedly effective and 5 cases of effective patients in the observation group of, which he clinical curative effect was significantly better than that of control group (P<0.05). After 3 months and 6 months treatment, AST, ALT, TBil, CHO levels in two groups were decreased compared with that before treatment, and TBA, PLIP levels were increased. The liver function of patientsin the observation group was obviously better than that in the control group with the statistical significance difference (P<0.05). However, the symptoms such as the right upper quadrant pain, jaundice, chills, fever in the observation group was significantly improvedthan that of the control group. The incidence of complications including nausea and vomiting, fatiguewas 4.76%, significantly lower than that 19.05% in the control group (P<0.05). After 1 year follow-up, it was found that recurrence reoperation rate of observation group was significantly lower than that the control group. The difference was statistically significant (P<0.05). Conclusion: Theclinical curative effect of the ursodeoxycholic acid combined with holmium laser by laparoscopic choledochoscopy was distinct, whichcould effectively improve the undesirable complications, reduce the postoperative recurrence and reoperation rate. The main reason may be the combination therapy could improve the patients' associates, PLIP level, lower levels of AST, ALT, TB il and CHO, which helped to improve liver function, reduce the cholestasis, prevent the recurrence of liver and gallbladder stones, and promote good prognosis.展开更多
Objective: To observe the curative effect of laparotomy combined with choledochoscopy in the clinical treatment of 48 patients with biliary calculi. Methods: 48 patients with biliary calculi in our hospital were regar...Objective: To observe the curative effect of laparotomy combined with choledochoscopy in the clinical treatment of 48 patients with biliary calculi. Methods: 48 patients with biliary calculi in our hospital were regarded as the target of experimental observation. The operation time range was from January 2017 to January 2021. The patients were divided into the conventional group, the observation group and a group of 24 patients by systematic sampling method. The conventional group only used open surgery, while the observation group used open surgery combined with choledochoscope exploration surgery. The quality of life and complications of the two groups were compared. Results: the scores of physical pain in the observation group were lower than those in the routine group, and the scores of physiological function, mental state and general health were higher than those in the routine group. The total incidence of complications in the observation group was lower than that in the conventional group. Conclusion: By observing the treatment results of 48 patients with biliary calculi, it can be seen that open surgery combined with choledochoscopy is better than open surgery, and can better promote the physical rehabilitation of patients.展开更多
Objective: to explore the clinical experience of treating 48 cases of gallbladder polyp complicated with cholecystolithiasis by laparoscopy and choledochoscope. Methods: from July 2019 to May 2020, laparoscopic resect...Objective: to explore the clinical experience of treating 48 cases of gallbladder polyp complicated with cholecystolithiasis by laparoscopy and choledochoscope. Methods: from July 2019 to May 2020, laparoscopic resection was performed in group A and laparoscopy combined with choledochoscope was performed in group B, with 48 cases in each group. The therapeutic effect and clinical related indexes were observed. Results: compared with group A, the incidence of complications in group B was lower and the related indexes during and after operation was better (P < 0.05). Conclusion: laparoscopy combined with choledochoscope is more effective for the treatment of gallbladder polyps complicated with gallbladder stones. It can effectively accelerate the rehabilitation process of patients after operation, and significantly improve the treatment effect of patients. It has high clinical application value and is worthy of popularization and application.展开更多
文摘To the Editor:Intraductal papillary neoplasm of the bile duct(IPNB)may occur in the setting of primary sclerosing cholangitis,choledochal cysts or hepatolithiasis[1].The entity may be a precursor of cancer or intrahepatic cholangiocarcinoma.Invasive carcinoma,tubular or mucinous adenocarcinoma is present in approximately 40%-80%of IPNBs[1–3].IPNB is frequently found in the resection margins of patients undergoing hepatectomy for cholangiocarcinoma[4].
文摘BACKGROUND In the last decade, confocal laser endomicroscopy (CLE) has emerged as a newendoscopic imaging modality for real-time in vivo histological examination at themicroscopic level. CLE has been shown to be useful for distinguishing benign andmalignant lesions and has been widely used in many digestive diseases. In ourstudy, we used CLE for the first time to examine the morphology of cholesterolpolyps as well as the different parts of normal gallbladder mucosa.CASE SUMMARY A 57-year-old woman was diagnosed by ultrasound with a polyp of 21 mm in thegallbladder wall. She consented to polyp removal by laparoscopic choledochoscopy.During laparoscopic cholecystectomy combined with choledochoscopicpolyp resection, CLE was used to observe the morphology of the polyp surfacecells. The appearance of the mucosa and microvessels in various parts of thegallbladder were also observed under CLE. Through comparison betweenpostoperative pathology and intraoperative CLE diagnosis, the reliability ofintraoperative CLE diagnosis was confirmed. CLE is a reliable method to examineliving cell pathology during cholecystectomy. Based on our practice, CLE shouldbe prioritized in the diagnosis of gallbladder polyps.CONCLUSION Compared with traditional histological examination, CLE has several advantages.We believe that CLE has great potential in this field.
基金supported by the Natural Science Foundation of Hunan Province(2024JJ4095)Scientific Research Project of Hunan Provincial Health Commission(202204010011 and B202303027830)Project Program of National Clinical Research Center for Geriatric Disorders(2022LNJJ19).
文摘Photodynamic therapy(PDT)has emerged as a prominent modality in the therapeutic armamentarium against malignant tumors,particularly those originating from the cutaneous and mucosal tissues(1).The principle of PDT involves the administration of a photosensitizing agent that selectively accumulates within neoplastic cells(2).Upon exposure to laser light of specific wavelengths,the photosensitizer becomes activated,triggering the generation of reactive oxygen species(ROS)such as oxygen radicals(3).This process culminates in cellular damage and subsequent tumor destruction.PDT holds promise as a localized therapeutic option for unresectable or recurrent cholangiocarcinomas(4).
基金Supported by Health Research Program of Anhui,No.AHWJ2023A30034.
文摘BACKGROUND In recent years,the use of ultrafine choledochoscopy has gradually increased in the treatment of cholelithiasis.However,stone incarceration and residual spasm of the sphincter of Oddi may be inevitable when an ultrafine choledochoscope is used alone.AIM To investigate the safety and feasibility of ultrafine choledochoscopy combined with low-dose atropine in the treatment of Oddi intersphincter stones.METHODS Seventeen patients with Oddi intersphincter stones were retrospectively analyzed.The perioperative clinical data and follow-up information were collected.RESULTS Among the 17 patients,3 were male and 14 were female.The mean age was 40.6±13.9 years,and the mean diameter of the common bile duct was 7.8±1.3 mm.All patients successfully underwent Oddi intersphincter stone removal using a combination of ultrafine choledochoscopy and low-dose atropine.No serious complications,such as postoperative hemorrhage,pancreatitis or bile leakage occurred in the 17 patients.During the one-year follow-up,none of the patients experienced stone recurrence.CONCLUSION Ultrafine choledochoscopy combined with low-dose atropine is safe and feasible for the treatment of Oddi intersphincter stones.
基金the Science and Technology Commission of Shanghai Municipality(No.18441900500)。
文摘Soft fiberoptic choledochoscope is an important tool for the diagnose and surgical treatment of biliary disease.However,the traditional soft fiberoptic choledochoscope is hard to operate,due to the low position accuracy.Based on the conventional soft fiberoptic choledochoscope,an electrical soft fiberoptic choledochoscope robot with a low latency was developed.In order to improve the controllability of the conventional choledochoscope,the wire traction mechanism and the rotation mechanism are used to bend and rotate the scope,so as to control its movement orientation.The dead band compensation model and control algorithm of the wire traction mechanism are developed to improve the accuracy of the orientation control.The human-computer interaction system and complex motion control system are developed based on ARM embedded system and FPGA.Thanks to the high-speed synchronization channel between FPGA and peripheral,the design of low latency whole-procedure surgical mode was established and verified.Combined with a micro image sensor,real-time video back transmission was realized.The performance of the robot prototype was verified by animal experiment in vivo on a pig.The robot has an extremely low operating latency of no more than 0.402 ms,and a high bending positioning accuracy of±1.43°error margin within 99.7%confidence interval,which guarantees the safety of biliary surgery.
文摘AIM:To introduce and evaluate the new method used in treatment of pancreatic and peripancreatic infections secondary to severe acute pancreatitis(SAP).METHODS:A total of 42 SAP patients initially underwent ultrasound-guided percutaneous puncture and catheterization.An 8-Fr drainage catheter was used to drain the infected peripancreatic necrotic foci for 3-5 d.The sinus tract of the drainage catheter was expanded gradually with a skin expander,and the 8-Fr drainage catheter was replaced with a 22-Fr drainage tube after 7-10 d.Choledochoscope-guided debridement was performed repeatedly until the infected peripancreatic tissue was effectively removed through the drainage sinus tract.RESULTS:Among the 42 patients,the infected peripancreatic tissue or abscess was completely removed from 38 patients and elective cyst-jejunum anastomosis was performed in 4 patients due to formation of pancreatic pseudocysts.No death and complication occurred during the procedure.CONCLUSION:Percutaneous catheter drainage in combination with choledochoscope-guided debridement is a simple,safe and reliable treatment procedure for peripancreatic infections secondary to SAP.
文摘When a distal common bile duct neoplasm is at the stage of carcinoma in situ or high-grade dysplasia,it is difficult for the surgeon to decide whether to perform pancreaticoduodenectomy.Here we describe a patient with a progressive dysplastic lesion in the common bile duct,which developed from moderate-high to highgrade dysplasia in approximately 2 mo.The patient refused major surgery.Therefore,endoscopic-assisted photodynamic therapy was performed.The result at follow-up using a trans-T-tube choledochoscope showed that the lesion was completely necrotic.This report is the first to describe the successful treatment of highgrade dysplasia of the distal bile duct using photodynamic therapy via a choledochoscope.
文摘AIM： To assess the effects of H2-receptor blocking pharmacon, protease inhibitor, and gastro kinetic agents on the human Sphincter of Oddi （SO） motility by choledochoscope manometry. METHODS： One hundred and seventy-five patients with T tube installed after cholecystectomy and choledochotomy were assessed by choledochoscope manometry. They were randomly assigned into groups of H2-receptor blocking pharmacon, protease inhibitor, and gastro kinetic agents. The Sphincter of Oddi basal pressure （SOBP）, amplitude （SOCA）, frequency of contractions （SOF）, duodenal pressure （DP）, and common bile duct pressure （CBDP） were scored and analyzed. RESULTS： SOBP and SOCA were significantly decreased after Cimetidine administration, and no statistical difference was seen in the Famotidine group. In the Gabexate mesilate group, SOBP had decreased significantly. In the Ulinastatin group, SOCA decreased when Ulinastatin was given at the rate of 2500 U/min; when Ulinastatin administration was raised to 5000 U/ rain, SOBP, SOF and SOCA all experienced a fall. SOBP and SOCA for Domperidone and SOCA for Mosapride groups all decreased distinctly after administration. CONCLUSION： The regular dosage of Cimetidine showed an inhibitory effect on the motility of SO, while Famotidine had no obvious effects otherwise. Gabnexata mesilate, Ulinastatin and gastro kinetic agents also showed inhibitory effects on the SO motility.
文摘BACKGROUND Endoscopically or fluoroscopically guided dilation is a safe and effective alternative to surgery for patients with benign strictures of the gastric outlet.CASE SUMMARY We describe two cases where a novel approach with a Spyglass~? choledochoscope in assessing the extent of benign duodenal strictures and aiding in placement of duodenal stents for treatment of the strictures. Choledochoscope-guided wire and stent placement was successful in all cases, leading to symptom resolution related to benign duodenal obstruction. No major adverse events were observed.CONCLUSION Choledochoscope-guided assessment and endoscopic therapy is a viable approach in relieving duodenal obstruction, if the conventional combined fluoroscopic and endoscopic methods fail.
基金Hainan health and family planning industry research project (19A200054)
文摘Objective: To investigate the effect of clinical ursodeoxycholic acid combined with holmium laser by laparoscopic choledochoscopy in the treatment of intrahepatic and intrahepatic bile duct stones. Methods: Patients with intrahepatic and intrahepatic bile duct stones treated by surgery in our hospital from October 2017 to December 2018 were randomly divided into control group and observation group.Patients in the control group were treated with laparoscopic choledochoscopy combined with holmium laser lithotripsy, and patients of the observation group were treated with ursodeoxycholic acid on the basis of the control group. The clinical efficacy, total bile acid (TBA), phospholipid (PLIP), cholesterol (CHO) levels and the incidence of complications of liver function and bile related indicators were compared between the two groups after 3 and 6 months treatment. Results: After 3 months treatment, there were 22 cases of cured patients, 11 cases of markedly effective and 5 cases of effective patients in the observation group of, which he clinical curative effect was significantly better than that of control group (P<0.05). After 3 months and 6 months treatment, AST, ALT, TBil, CHO levels in two groups were decreased compared with that before treatment, and TBA, PLIP levels were increased. The liver function of patientsin the observation group was obviously better than that in the control group with the statistical significance difference (P<0.05). However, the symptoms such as the right upper quadrant pain, jaundice, chills, fever in the observation group was significantly improvedthan that of the control group. The incidence of complications including nausea and vomiting, fatiguewas 4.76%, significantly lower than that 19.05% in the control group (P<0.05). After 1 year follow-up, it was found that recurrence reoperation rate of observation group was significantly lower than that the control group. The difference was statistically significant (P<0.05). Conclusion: Theclinical curative effect of the ursodeoxycholic acid combined with holmium laser by laparoscopic choledochoscopy was distinct, whichcould effectively improve the undesirable complications, reduce the postoperative recurrence and reoperation rate. The main reason may be the combination therapy could improve the patients' associates, PLIP level, lower levels of AST, ALT, TB il and CHO, which helped to improve liver function, reduce the cholestasis, prevent the recurrence of liver and gallbladder stones, and promote good prognosis.
文摘Objective: To observe the curative effect of laparotomy combined with choledochoscopy in the clinical treatment of 48 patients with biliary calculi. Methods: 48 patients with biliary calculi in our hospital were regarded as the target of experimental observation. The operation time range was from January 2017 to January 2021. The patients were divided into the conventional group, the observation group and a group of 24 patients by systematic sampling method. The conventional group only used open surgery, while the observation group used open surgery combined with choledochoscope exploration surgery. The quality of life and complications of the two groups were compared. Results: the scores of physical pain in the observation group were lower than those in the routine group, and the scores of physiological function, mental state and general health were higher than those in the routine group. The total incidence of complications in the observation group was lower than that in the conventional group. Conclusion: By observing the treatment results of 48 patients with biliary calculi, it can be seen that open surgery combined with choledochoscopy is better than open surgery, and can better promote the physical rehabilitation of patients.
文摘Objective: to explore the clinical experience of treating 48 cases of gallbladder polyp complicated with cholecystolithiasis by laparoscopy and choledochoscope. Methods: from July 2019 to May 2020, laparoscopic resection was performed in group A and laparoscopy combined with choledochoscope was performed in group B, with 48 cases in each group. The therapeutic effect and clinical related indexes were observed. Results: compared with group A, the incidence of complications in group B was lower and the related indexes during and after operation was better (P < 0.05). Conclusion: laparoscopy combined with choledochoscope is more effective for the treatment of gallbladder polyps complicated with gallbladder stones. It can effectively accelerate the rehabilitation process of patients after operation, and significantly improve the treatment effect of patients. It has high clinical application value and is worthy of popularization and application.
