高血压是心血管疾病重要的危险因素,对于高血压的防治主要以药物控制和生活方式干预为主。重新建立良好生活方式可使药物治疗更好发挥疗效,利于患者血压的控制使其维持在正常范围。生活方式干预中,饮食控制至关重要。其中,DASH饮食可用...高血压是心血管疾病重要的危险因素,对于高血压的防治主要以药物控制和生活方式干预为主。重新建立良好生活方式可使药物治疗更好发挥疗效,利于患者血压的控制使其维持在正常范围。生活方式干预中,饮食控制至关重要。其中,DASH饮食可用于高血压的饮食护理,降低血压作用显著。在中国饮食文化中,生活在不同地区的人们也有着不同的饮食习惯,不同的菜系具有浓郁的当地特色。基于此情况,“一刀切”可能不起作用,因此必须开发一种结合主要中国菜特色的中式心脏健康(CHH)饮食来有效降低中国高血压成年人的血压,适用于中国的烹饪文化。辣膳食模式也是由我国提出的饮食方式,辣椒素是主要营养物质。为探讨这三种模式在高血压饮食护理中的作用,现将具体内容展开如下综述。Hypertension is an important risk factor for cardiovascular disease, and the prevention and treatment of hypertension is mainly based on drug control and lifestyle intervention. Re-establishing a healthy lifestyle can make drug therapy more effective and help control the patient’s blood pressure to maintain the normal range. Dietary control is essential among lifestyle interventions. Thereinto the DASH diet can be used for the dietary care of hypertension and has a significant effect on lowering blood pressure. In addition, in the same Chinese food culture, people living in different regions also consume food in different ways, and different cuisines have strong local characteristics. Based on this, a “one-size-fits-all” diet may not work, so it is necessary to develop a Chinese-style heart health (CHH) diet that combines the characteristics of major Chinese cuisine and is clinically effective in lowering blood pressure in Chinese hypertensive adults, applicable to major Chinese culinary cultures. The spicy meal pattern is also a dietary pattern proposed by our country, and capsaicin is the main nutrient. In order to explore the role of these three modes in the dietary care of hypertension, the specific contents are summarized as follows.展开更多
Eyestalk ablation has been widely used in artificial breeding of crustaceans due to its significant promotion effect on gonadal development, which plays a certain role by directly affecting neuroendocrine function of ...Eyestalk ablation has been widely used in artificial breeding of crustaceans due to its significant promotion effect on gonadal development, which plays a certain role by directly affecting neuroendocrine function of X-organ sinus gland （XO-SG） complex in eyestalks. As an important endocrine organ, XO-SG complex of the eyestalk has become a hot issue in crustacean endocrinology. This paper introduced the biological structure and physiological functions of XO-SG complex and summarized the molecular mechanism of eyestalk neuroendocrine, which provided theoretical references for further revealing the regulatory mechanism of eyestalk neuroendocrine system.展开更多
ObjectiveToanalyze clinica1l and genetic characteristics of congenital hypogonadotropic hypogonadism(CHH)in children.Methods Clinical data of O-18 year old CHH patients diagnosed in the Department of Endocrinology,Gen...ObjectiveToanalyze clinica1l and genetic characteristics of congenital hypogonadotropic hypogonadism(CHH)in children.Methods Clinical data of O-18 year old CHH patients diagnosed in the Department of Endocrinology,Genetics and Metabolism of Children's Hospital Affiliated to Zhengzhou University from January 1,2016 to December 31,2023 were retrospectively analyzed,including their hormone levels and genetic test results.Results A total of 95 patients with CHH were included.Among them,25 were diagnosed before the age of 3,37 between the ages of 3-14,and 33 were over 14 years old at the time of first diagnosis.The primary manifestations were micropenis(95 cases,100%)and cryptorchidism(46 cases,48.5%).The incidence of cryptorchidism was the lowest in the group over 14 years of age.Hormonal analysis revealed that the peak levels of LH following statin B and GnRH stimulation,the peak levels of FSH after GnRH stimulation,and testosterone levels following hCG stimulation were the highest in the infant group.Genetic analysis identified 20 CHH-related genes in 61 out of 77 cases.Doublegene mutation accounted for 7.8%(6/77)and triple-gene mutation accounted for 3.9%(3/77).The most common mutations were FGFR1(18/77,23.4%),,CHD7(12/77,15.6%),PROKR2(11/77,14.3%)and ANOSI(6/77,7.8%).The incidence of cryptorchidism in these four genotypes was 50%,75%,45.5%and 83.3%,respectively.The incidence of testicular dysfunction was 22.2%,16.7%,27.3%,and 16.7%,respectively,with no statistical significance.Conclusion The primary manifestation of CHH is micropenis and cryptorchidism.In children with CHH,the incidence of testicular Leydig cell and Sertoli cell dysfunction increased with age in CHH children.FCFR1,CHD7,PROKR22andANOS1 are common variants of CHH.展开更多
In this paper, by analyzing the context of the relevant records, the author argues that Xiao-chen (小臣), who appeared frequently in paleographical data and ancient documents but still unidentified so far, were those ...In this paper, by analyzing the context of the relevant records, the author argues that Xiao-chen (小臣), who appeared frequently in paleographical data and ancient documents but still unidentified so far, were those people that served for their masters who belonged to different clans. Therefore, Xiao-chen (小臣 ) had complicated identities depending on the status in their own clans before they became Xiao-chen (小臣).展开更多
文摘高血压是心血管疾病重要的危险因素,对于高血压的防治主要以药物控制和生活方式干预为主。重新建立良好生活方式可使药物治疗更好发挥疗效,利于患者血压的控制使其维持在正常范围。生活方式干预中,饮食控制至关重要。其中,DASH饮食可用于高血压的饮食护理,降低血压作用显著。在中国饮食文化中,生活在不同地区的人们也有着不同的饮食习惯,不同的菜系具有浓郁的当地特色。基于此情况,“一刀切”可能不起作用,因此必须开发一种结合主要中国菜特色的中式心脏健康(CHH)饮食来有效降低中国高血压成年人的血压,适用于中国的烹饪文化。辣膳食模式也是由我国提出的饮食方式,辣椒素是主要营养物质。为探讨这三种模式在高血压饮食护理中的作用,现将具体内容展开如下综述。Hypertension is an important risk factor for cardiovascular disease, and the prevention and treatment of hypertension is mainly based on drug control and lifestyle intervention. Re-establishing a healthy lifestyle can make drug therapy more effective and help control the patient’s blood pressure to maintain the normal range. Dietary control is essential among lifestyle interventions. Thereinto the DASH diet can be used for the dietary care of hypertension and has a significant effect on lowering blood pressure. In addition, in the same Chinese food culture, people living in different regions also consume food in different ways, and different cuisines have strong local characteristics. Based on this, a “one-size-fits-all” diet may not work, so it is necessary to develop a Chinese-style heart health (CHH) diet that combines the characteristics of major Chinese cuisine and is clinically effective in lowering blood pressure in Chinese hypertensive adults, applicable to major Chinese culinary cultures. The spicy meal pattern is also a dietary pattern proposed by our country, and capsaicin is the main nutrient. In order to explore the role of these three modes in the dietary care of hypertension, the specific contents are summarized as follows.
基金Supported by Special Fund for Agro-scientific Research in the Public Interest(201003070)Youth Fund from Natural Science Foundation of Jiangsu Province(BK2012090)Central Public-interest Scientific Institution Basal Research Fund(2013JBFM09)
文摘Eyestalk ablation has been widely used in artificial breeding of crustaceans due to its significant promotion effect on gonadal development, which plays a certain role by directly affecting neuroendocrine function of X-organ sinus gland （XO-SG） complex in eyestalks. As an important endocrine organ, XO-SG complex of the eyestalk has become a hot issue in crustacean endocrinology. This paper introduced the biological structure and physiological functions of XO-SG complex and summarized the molecular mechanism of eyestalk neuroendocrine, which provided theoretical references for further revealing the regulatory mechanism of eyestalk neuroendocrine system.
文摘ObjectiveToanalyze clinica1l and genetic characteristics of congenital hypogonadotropic hypogonadism(CHH)in children.Methods Clinical data of O-18 year old CHH patients diagnosed in the Department of Endocrinology,Genetics and Metabolism of Children's Hospital Affiliated to Zhengzhou University from January 1,2016 to December 31,2023 were retrospectively analyzed,including their hormone levels and genetic test results.Results A total of 95 patients with CHH were included.Among them,25 were diagnosed before the age of 3,37 between the ages of 3-14,and 33 were over 14 years old at the time of first diagnosis.The primary manifestations were micropenis(95 cases,100%)and cryptorchidism(46 cases,48.5%).The incidence of cryptorchidism was the lowest in the group over 14 years of age.Hormonal analysis revealed that the peak levels of LH following statin B and GnRH stimulation,the peak levels of FSH after GnRH stimulation,and testosterone levels following hCG stimulation were the highest in the infant group.Genetic analysis identified 20 CHH-related genes in 61 out of 77 cases.Doublegene mutation accounted for 7.8%(6/77)and triple-gene mutation accounted for 3.9%(3/77).The most common mutations were FGFR1(18/77,23.4%),,CHD7(12/77,15.6%),PROKR2(11/77,14.3%)and ANOSI(6/77,7.8%).The incidence of cryptorchidism in these four genotypes was 50%,75%,45.5%and 83.3%,respectively.The incidence of testicular dysfunction was 22.2%,16.7%,27.3%,and 16.7%,respectively,with no statistical significance.Conclusion The primary manifestation of CHH is micropenis and cryptorchidism.In children with CHH,the incidence of testicular Leydig cell and Sertoli cell dysfunction increased with age in CHH children.FCFR1,CHD7,PROKR22andANOS1 are common variants of CHH.
文摘In this paper, by analyzing the context of the relevant records, the author argues that Xiao-chen (小臣), who appeared frequently in paleographical data and ancient documents but still unidentified so far, were those people that served for their masters who belonged to different clans. Therefore, Xiao-chen (小臣 ) had complicated identities depending on the status in their own clans before they became Xiao-chen (小臣).
