Objective:To study the effect of Chaishao Jieyu Decoction on the improvement of mental state、immune function and diarrhea of Liver Depression and Spleen Deficiency patients with colorectal cancer after operation.Meth...Objective:To study the effect of Chaishao Jieyu Decoction on the improvement of mental state、immune function and diarrhea of Liver Depression and Spleen Deficiency patients with colorectal cancer after operation.Methods:76 cases of colorectal cancer patients after operation,according to the method of random grouping would be divided into the chinese medicine treatment(CMT)group and the western medicine control(WMC)group,each group 38 cases.The WMC group were treated with montmorillonite.The CMT group accepted oral administration of Chaishao Jieyu Decoction.The levels of anxiety and depression score,quality of life,T lymphocyte subsets and TNF-α,and improvement of diarrhea were compared.Results:With the therapy ending,the standards of SAS and SDS in CMT group were reduced signficantly than the WMC group(P<0.05),The score of QOL was obviously higher than the WMC group(P<0.05),the treatment group's CD3+、CD4+subsets levels increased obviously than the WMC group(P<0.05),the CD8+subsets and Tumor necrosis factor-alpha-levels were obviously lower than the WMC group(P<0.05),the improvement of diarrhea of the CMT group was obviously better than the WMC group(P<0.05).Conclusion:Chaishao Jieyu Decoction can effectively improve the mental state and diarrhea symptoms of postoperative patients with colorectal cancer,and significantly improve the immune function of the body,the Chaishao Jieyu Decoction's effect is excellent.展开更多
Objective:To study the improvement of Chaishao Jieyu decoction combined with Pingxiao capsule on the mental state、immune function and endometrium of patients with luminal breast cancer undergoing endocrine therapy af...Objective:To study the improvement of Chaishao Jieyu decoction combined with Pingxiao capsule on the mental state、immune function and endometrium of patients with luminal breast cancer undergoing endocrine therapy after operation.Methods:60 cases of luminal breast cancer patients after operation,according to the method of random grouping would be divided into the control group and the observation group,each group 30 cases.The control group were treated with tamoxifen.On the basis,the observation group accepted oral administration of Chaishao Jieyu Decoction and Pingxiao capsule.The levels of 5-HT、DA、T lymphocyte subsets、IGF-1 and endometrial thickness were compared.Results:At the end of treatment,the observation group's 5-HT、DA、CD3+、CD4+levels were obviously higher than the control group(P<0.05),the observation group's CD8+levels、IGF-1 levels and endometrial thickness were significantly lower than the control group(P<0.05).Conclusion:Chaishao Jieyu Decoction combined with Pingxiao capsule can significantly improve the mental state、immune function of patients with luminal breast cancer undergoing endocrine therapy after surgery,and inhibit their endometrial thickening,the effect is exact.展开更多
Objective:To explore the curative effect of Chaishao Chengqi Decoction on moderate to severe acute pancreatitis of heat stagnation and Fu-organ excess type and its effect on inflammatory reaction,and to provide new id...Objective:To explore the curative effect of Chaishao Chengqi Decoction on moderate to severe acute pancreatitis of heat stagnation and Fu-organ excess type and its effect on inflammatory reaction,and to provide new ideas for clinical treatment and prognosis evaluation.Methods:60 patients with moderate to severe acute pancreatitis of heat stagnation and Fu-organ excess type from June 2017 to June 2019 were randomly divided into control group treated with conventional therapy and treatment group treated with Chaishao Chengqi Decoction for 2 weeks.The differences of clinical efficacy and TCM syndromes between the two groups were compared.Ranson score,Balthazar CTSI score,SIRS score and modified Marshall score were recorded before and after treatment.The levels of inflammatory factors and oxidative stress-related molecules were compared before and after treatment.Result:After treatment,the total effective rates of the control group and the treatment group were 80.0%and 93.3%,respectively,with statistical difference(χ2=8.845,P=0.027);after treatment,the total effective rates of TCM syndromes evaluation of the control group and the treatment group were 76.7%and 93.3%,respectively,with statistical difference(χ2=10.024,P=0.012);after treatment,the Ranson score,Balthazar CTSI score,SIRS score and improved Marshall score were all significantly decreased(P<0.05),and the decrease was more significant in the treatment group(P<0.05);after treatment,the serum levels of TNF-α,IL-6 and MDA were significantly decreased in both groups,and superoxide dismutase(SOD)was significantly increased(P<0.05),and the treatment group improved more(P<0.05).Conclusion:Chaishao Chengqi Decoction has a good curative effect on moderate to severe acute pancreatitis of heat stagnation and Fu-organ excess type,and can effectively improve inflammatory response and oxidative stress,which has a high clinical significance.展开更多
Objective: to study the therapeutic effect of chemotherapy combined with Chaishao Liujunzi decoction on breast cancer. Methods: 130 cases of breast cancer patients admitted to our hospital from September 2020 to Septe...Objective: to study the therapeutic effect of chemotherapy combined with Chaishao Liujunzi decoction on breast cancer. Methods: 130 cases of breast cancer patients admitted to our hospital from September 2020 to September 2021 were randomly divided into control group and experimental group according to the computer method. There were 65 cases in each group, and the patients in the control group received routine chemotherapy and medication. The patients in the experimental group were treated with Chaishao Liujunzi Decoction on the basis of the control group. The curative effect, TCM symptom score before and after the intervention and myelosuppression status (platelet count, white blood cell count and hemoglobin concentration) of the two groups were compared. Results: compared with the effective rate of comprehensive treatment, 64 cases (98.46%) in the experimental group and 58 cases (89.23%) in the control group were comprehensively effective (P < 0.05). Before treatment, there was no significant difference between the two groups (P>0.05). After treatment, the TCM waiting score of the experimental group was better than that of the control group (P<0.05). Before treatment, there was no significant difference in platelet count, leukocyte count and hemoglobin concentration between the two groups (P > 0.05). After treatment, the measurement results of various myelosuppression indexes in the experimental group were significantly better than those in the control group (P < 0.05). The incidence of adverse reactions in the experimental group on the 2nd day of chemotherapy was significantly lower than that in the control group (p < 0.05). Conclusion: the application of Chaishao Liujunzi Decoction in the clinical treatment of breast cancer patients undergoing chemotherapy can improve the patient's symptoms, and the curative effect is ideal. It is recommended to be popularized.展开更多
基金Youth project of national natural science foundation(No.81803711)
文摘Objective:To study the effect of Chaishao Jieyu Decoction on the improvement of mental state、immune function and diarrhea of Liver Depression and Spleen Deficiency patients with colorectal cancer after operation.Methods:76 cases of colorectal cancer patients after operation,according to the method of random grouping would be divided into the chinese medicine treatment(CMT)group and the western medicine control(WMC)group,each group 38 cases.The WMC group were treated with montmorillonite.The CMT group accepted oral administration of Chaishao Jieyu Decoction.The levels of anxiety and depression score,quality of life,T lymphocyte subsets and TNF-α,and improvement of diarrhea were compared.Results:With the therapy ending,the standards of SAS and SDS in CMT group were reduced signficantly than the WMC group(P<0.05),The score of QOL was obviously higher than the WMC group(P<0.05),the treatment group's CD3+、CD4+subsets levels increased obviously than the WMC group(P<0.05),the CD8+subsets and Tumor necrosis factor-alpha-levels were obviously lower than the WMC group(P<0.05),the improvement of diarrhea of the CMT group was obviously better than the WMC group(P<0.05).Conclusion:Chaishao Jieyu Decoction can effectively improve the mental state and diarrhea symptoms of postoperative patients with colorectal cancer,and significantly improve the immune function of the body,the Chaishao Jieyu Decoction's effect is excellent.
基金Special project of national traditional Chinese medicine clinical research base of state administration of traditional Chinese medicine(No.JDZX2015057)
文摘Objective:To study the improvement of Chaishao Jieyu decoction combined with Pingxiao capsule on the mental state、immune function and endometrium of patients with luminal breast cancer undergoing endocrine therapy after operation.Methods:60 cases of luminal breast cancer patients after operation,according to the method of random grouping would be divided into the control group and the observation group,each group 30 cases.The control group were treated with tamoxifen.On the basis,the observation group accepted oral administration of Chaishao Jieyu Decoction and Pingxiao capsule.The levels of 5-HT、DA、T lymphocyte subsets、IGF-1 and endometrial thickness were compared.Results:At the end of treatment,the observation group's 5-HT、DA、CD3+、CD4+levels were obviously higher than the control group(P<0.05),the observation group's CD8+levels、IGF-1 levels and endometrial thickness were significantly lower than the control group(P<0.05).Conclusion:Chaishao Jieyu Decoction combined with Pingxiao capsule can significantly improve the mental state、immune function of patients with luminal breast cancer undergoing endocrine therapy after surgery,and inhibit their endometrial thickening,the effect is exact.
基金Zhangjiagang municipal commission of health and family planning system youth science and technology project in 2018(ZJGQNLKJ201813).
文摘Objective:To explore the curative effect of Chaishao Chengqi Decoction on moderate to severe acute pancreatitis of heat stagnation and Fu-organ excess type and its effect on inflammatory reaction,and to provide new ideas for clinical treatment and prognosis evaluation.Methods:60 patients with moderate to severe acute pancreatitis of heat stagnation and Fu-organ excess type from June 2017 to June 2019 were randomly divided into control group treated with conventional therapy and treatment group treated with Chaishao Chengqi Decoction for 2 weeks.The differences of clinical efficacy and TCM syndromes between the two groups were compared.Ranson score,Balthazar CTSI score,SIRS score and modified Marshall score were recorded before and after treatment.The levels of inflammatory factors and oxidative stress-related molecules were compared before and after treatment.Result:After treatment,the total effective rates of the control group and the treatment group were 80.0%and 93.3%,respectively,with statistical difference(χ2=8.845,P=0.027);after treatment,the total effective rates of TCM syndromes evaluation of the control group and the treatment group were 76.7%and 93.3%,respectively,with statistical difference(χ2=10.024,P=0.012);after treatment,the Ranson score,Balthazar CTSI score,SIRS score and improved Marshall score were all significantly decreased(P<0.05),and the decrease was more significant in the treatment group(P<0.05);after treatment,the serum levels of TNF-α,IL-6 and MDA were significantly decreased in both groups,and superoxide dismutase(SOD)was significantly increased(P<0.05),and the treatment group improved more(P<0.05).Conclusion:Chaishao Chengqi Decoction has a good curative effect on moderate to severe acute pancreatitis of heat stagnation and Fu-organ excess type,and can effectively improve inflammatory response and oxidative stress,which has a high clinical significance.
文摘Objective: to study the therapeutic effect of chemotherapy combined with Chaishao Liujunzi decoction on breast cancer. Methods: 130 cases of breast cancer patients admitted to our hospital from September 2020 to September 2021 were randomly divided into control group and experimental group according to the computer method. There were 65 cases in each group, and the patients in the control group received routine chemotherapy and medication. The patients in the experimental group were treated with Chaishao Liujunzi Decoction on the basis of the control group. The curative effect, TCM symptom score before and after the intervention and myelosuppression status (platelet count, white blood cell count and hemoglobin concentration) of the two groups were compared. Results: compared with the effective rate of comprehensive treatment, 64 cases (98.46%) in the experimental group and 58 cases (89.23%) in the control group were comprehensively effective (P < 0.05). Before treatment, there was no significant difference between the two groups (P>0.05). After treatment, the TCM waiting score of the experimental group was better than that of the control group (P<0.05). Before treatment, there was no significant difference in platelet count, leukocyte count and hemoglobin concentration between the two groups (P > 0.05). After treatment, the measurement results of various myelosuppression indexes in the experimental group were significantly better than those in the control group (P < 0.05). The incidence of adverse reactions in the experimental group on the 2nd day of chemotherapy was significantly lower than that in the control group (p < 0.05). Conclusion: the application of Chaishao Liujunzi Decoction in the clinical treatment of breast cancer patients undergoing chemotherapy can improve the patient's symptoms, and the curative effect is ideal. It is recommended to be popularized.
