In order to reduce power consumption of sensor nodes and extend network survival time in the wireless sensor network （WSN）, sensor nodes are scheduled in an active or dormant mode. A chain-type WSN is fundamental y ...In order to reduce power consumption of sensor nodes and extend network survival time in the wireless sensor network （WSN）, sensor nodes are scheduled in an active or dormant mode. A chain-type WSN is fundamental y different from other types of WSNs, in which the sensor nodes are deployed along elongated geographic areas and form a chain-type network topo-logy structure. This paper investigates the node scheduling prob-lem in the chain-type WSN. Firstly, a node dormant scheduling mode is analyzed theoretical y from geographic coverage, and then three neighboring nodes scheduling criteria are proposed. Sec-ondly, a hybrid coverage scheduling algorithm and dead areas are presented. Final y, node scheduling in mine tunnel WSN with uniform deployment （UD）, non-uniform deployment （NUD） and op-timal distribution point spacing （ODS） is simulated. The results show that the node scheduling with UD and NUD, especial y NUD, can effectively extend the network survival time. Therefore, a strat-egy of adding a few mobile nodes which activate the network in dead areas is proposed, which can further extend the network survival time by balancing the energy consumption of nodes.展开更多
In this paper, we have established the existence theorem of the weak solution of theboundary problems for systems of ferro-magnetic chain ty means of the viscosity eliminatingmethod and the Leray-Schauder fixed point ...In this paper, we have established the existence theorem of the weak solution of theboundary problems for systems of ferro-magnetic chain ty means of the viscosity eliminatingmethod and the Leray-Schauder fixed point argument.展开更多
The exact solutions of a chain of type Ⅱ are investigated. The chain of type Ⅱ is first transformed to an integrable differential-difference equation, which has the Kaup Newell spectral problem as its continuous spa...The exact solutions of a chain of type Ⅱ are investigated. The chain of type Ⅱ is first transformed to an integrable differential-difference equation, which has the Kaup Newell spectral problem as its continuous spatial spectral problem and a Darboux transformation of the Kaup-Newell equation as its discrete temporal spectral problem. Then, with these spectral problems, a Darboux transformation of the transformed equation is constructed. Finally, as an application of the Darboux transformation, an exact solution of the transformed equation and thus the chain of type Ⅱ are presented.展开更多
Ta_4(Te_2)_4Te_4I,Mr=2381.90,Monoclinic,C2/c,a=21.987(2),b=6.153(2),c= 19.936(3),β=122.42(14),V=2276.7 ~3,z=4,Dm=6.8(5)g/cm^3,Dc=6.95g/cm^3,λ(Mok)= 0.71073,μ=354.0cm^(-1),F(000)=3876,T=296(1)k,R=5.3%,Rw=6.8%,for 11...Ta_4(Te_2)_4Te_4I,Mr=2381.90,Monoclinic,C2/c,a=21.987(2),b=6.153(2),c= 19.936(3),β=122.42(14),V=2276.7 ~3,z=4,Dm=6.8(5)g/cm^3,Dc=6.95g/cm^3,λ(Mok)= 0.71073,μ=354.0cm^(-1),F(000)=3876,T=296(1)k,R=5.3%,Rw=6.8%,for 1118 unique observed reflections(1>3σ(Ⅰ)).The structure is composed of [Ta_4(Te_2)_4Te_4I]_∞~ chains,which are formed by the four-nuclear butterfly cluster units "Ta_4(Te_2)_4Te_4" with the Ⅰ atoms as the bridging atoms between different cluster units.展开更多
The glomerulonephritis disease is characterized by inflammation of glomeruli or small blood vessels in the kidney that causes kidney diseases. The reason of glomerulonephritis disease is to deposit the anti-GBM auto a...The glomerulonephritis disease is characterized by inflammation of glomeruli or small blood vessels in the kidney that causes kidney diseases. The reason of glomerulonephritis disease is to deposit the anti-GBM auto antibody in the glomerular basement membrane. The type IV collagen is the main component of glomerular basement membrane that has α3 chain of type (IV) collagen of non-collagenous domain which contains N-terminal 7S domain, a triple helical collagenous domain and C-terminal non-collagenous glomerular domain (NC1). The amino terminal of α3 (IV) NC1 that induces the Experimental Autoimmuno Glomerulonephritis (EAG) in rat model has been identified. The recombinant rat α3 (IV) NC1 antigen has nine amino acid spans that are consistent with antibody or T cell epitope that induces in EAG. The research is carried out on the recombinant rat α3 (IV) NC1 production, purification, quantification, and characterization. The circulation of anti-GBM antibody in glomerular basement membrane can be measured by the ELISA assay. In addition, the recombinant rat antigen is secreted in HEK293 cell supernatant that is purified by Anti-FLAG M2 monoclonal IgG antibody affinity column and characterized and quantified by SDS-PAGE gel electrophoresis and Western blotting techniques.展开更多
Based on space-charge wave theory, the formulae of the beam-wave coupling coefficient and the beam-loaded conductance are given for the beam-wave interaction in an N-gap Hughes-type coupled cavity chain. The ratio of ...Based on space-charge wave theory, the formulae of the beam-wave coupling coefficient and the beam-loaded conductance are given for the beam-wave interaction in an N-gap Hughes-type coupled cavity chain. The ratio of the nonbeam-loaded quality factor of the coupled cavity chain to the beam quality factor is used to determine the stability of the beam-wave interaction. As an example, the stabilities of the beam-wave interaction in a three-gap Hughes-type coupled cavity chain are discussed with the formulae and the CST code for the operations of the 2π, π, and π/2 modes, respectively. The results show that stable operation of the 2π, π, and π/2 modes may all be realized in an extended-interaction klystron with the three-gap Hughes-type coupled cavity chain.展开更多
A novel side chain liquid crystalline polymer (SCLCP) combining the polysiloxane as main chain with azo-based mesogen moieties as side chain through a flexible spacer has been synthesized by the hydrosilylation reacti...A novel side chain liquid crystalline polymer (SCLCP) combining the polysiloxane as main chain with azo-based mesogen moieties as side chain through a flexible spacer has been synthesized by the hydrosilylation reaction using Cp_2PtCl_2 as catalyst. The phase transition behavior of both side chain monomer (AZO-C_6C_(11))and polymer (P-AZO-C_6C_(11))has been characterized via combination of hot-stage polarized microscope, DSC and X-ray diffraction methods (including temperature-variation and quenching techniques). As normal, the transition process included K→S→N→I. Some pretransition features have been observed.展开更多
Background and objective:Botulinum toxin type A(BoNT/A)is a metalloprotease that blocks synaptic transmission via the cleavage of a synaptosomal-associated protein of 25 kDa(SNAP-25).It has gained widespread use as a ...Background and objective:Botulinum toxin type A(BoNT/A)is a metalloprotease that blocks synaptic transmission via the cleavage of a synaptosomal-associated protein of 25 kDa(SNAP-25).It has gained widespread use as a treatment for cerebral palsy and skeletal muscle hypertrophy.In China,Chinese botulinum toxin type A(CBTX-A),a type of BoNT/A,is in widespread clinical use.However,the changes in the morphological and biochemical properties of treated muscles and in remote muscles from the CBTX-A injection site are relatively unknown.Therefore,we investigated the changes in histomorphology and myosin heavy chain(MyHC)isoform composition and distribution in rat gastrocnemius muscles after intramuscular injection of CBTX-A.Methods:The weakness of the injected muscles was assessed periodically to identify their functional deficiency.Muscle slices were stained with hematoxylin-eosin(HE)and adenosine triphosphatase(ATPase).MyHC isoform composition was analyzed by sodium dodecyl sulfatepolyacrylamide gel electrophoresis(SDS-PAGE)to uncover changes in morphological and biochemical properties.Results:Our findings demonstrate that following injection of CBTX-A 5 U into rat gastrocnemius muscles,shifts in MyHC isoform composition emerged on the third day after injection and peaked in the fourth week.The composition remained distinctly different from that of the control group after the twelfth week.More specifically,there was a decrease in the proportion of the type IIb isoform and an increase in the proportions of type IIx,type IIa,and type I isoforms.Conclusions:Data revealed that CBTX-A led to a shift in MyHC composition towards slower isoforms and that the MyHC composition remained far from normal six months after a single injection.However,no noticeable remote muscle weakness was induced.展开更多
Amid the escalating plastic pollution issue, the development of biodegradable and recyclable polymeric materials has become a focus within the scientific community. Chain extenders, which are an important class of com...Amid the escalating plastic pollution issue, the development of biodegradable and recyclable polymeric materials has become a focus within the scientific community. Chain extenders, which are an important class of compounds, facilitate the elongation of polymer chains through reactive functional groups, thereby enhancing the performance of the materials. Epoxy-based chain extenders, due to their cost-effectiveness, low toxicity, high reaction efficiency, and effective reactivity with hydroxyl and carboxyl groups, have emerged as a promising class of chain extenders. This manuscript comprehensively elaborates on the varieties, structural characteristics, and performance of chain extenders, the challenges they face, and the methods for their modification. Special emphasis is placed on the application of epoxy-based chain extenders in biodegradable polymers, such as polylactic acid (PLA), and their subsequent influence on the structural and performance properties of these materials.展开更多
To avoid the existence of nonlinear and strong coupling in parallel mechanisms,it is necessary to address special care to the type synthesis of mechanisms,especially for the type synthesis of fully-decoupled parallel ...To avoid the existence of nonlinear and strong coupling in parallel mechanisms,it is necessary to address special care to the type synthesis of mechanisms,especially for the type synthesis of fully-decoupled parallel mechanisms. Based on the screw theory and the driven-chain principle,a methodology of structural synthesis for fully-decoupled three-rotational( 3R) and two-translational( 2T)parallel mechanisms was proposed by analyzing the characteristics of the input-output relations for fully-decoupled parallel mechanisms.Firstly,according to the desired kinematic characteristics of fullydecoupled parallel mechanisms,a method was presented by virtue of screw theory to synthesize the desired forms for both the direct and the inverse Jacobian matrices. Secondly,according to the feature of the direct and the inverse Jacobian matrices,the effective screws,the actuated screws and the mobile un-actuated screws of each leg were established based on the reciprocal screw theory and all possible topology structures fulfilling the requirements were obtained.Finally,the desired fully-decoupled parallel mechanisms could be synthesized by using the structural synthesis rule and structural synthesis of fully-decoupled 3R2 T parallel mechanisms could be obtained exploiting the abovementioned methodology. Furthermore,the Jacobian matrix of a synthesized 3R2 T parallel mechanism was deduced to demonstrate the decoupling feature of the parallel mechanism,which also validated the correctness of the methodology of the type synthesis for fully-decoupled 3R2 T parallel mechanisms.展开更多
基金supported by the China Doctoral Discipline New Teacher Foundation(200802901507)the Sichuan Province Basic Research Plan Project(2013JY0165)the Cultivating Programme of Excellent Innovation Team of Chengdu University of Technology(KYTD201301)
文摘In order to reduce power consumption of sensor nodes and extend network survival time in the wireless sensor network （WSN）, sensor nodes are scheduled in an active or dormant mode. A chain-type WSN is fundamental y different from other types of WSNs, in which the sensor nodes are deployed along elongated geographic areas and form a chain-type network topo-logy structure. This paper investigates the node scheduling prob-lem in the chain-type WSN. Firstly, a node dormant scheduling mode is analyzed theoretical y from geographic coverage, and then three neighboring nodes scheduling criteria are proposed. Sec-ondly, a hybrid coverage scheduling algorithm and dead areas are presented. Final y, node scheduling in mine tunnel WSN with uniform deployment （UD）, non-uniform deployment （NUD） and op-timal distribution point spacing （ODS） is simulated. The results show that the node scheduling with UD and NUD, especial y NUD, can effectively extend the network survival time. Therefore, a strat-egy of adding a few mobile nodes which activate the network in dead areas is proposed, which can further extend the network survival time by balancing the energy consumption of nodes.
基金Project supported by the National Natural, Science Foundation of China and CAEP.
文摘In this paper, we have established the existence theorem of the weak solution of theboundary problems for systems of ferro-magnetic chain ty means of the viscosity eliminatingmethod and the Leray-Schauder fixed point argument.
基金Project supported by the National Natural science Foundation of china and china Academy of Engineering Physics
文摘The global solvability of homogeneous boundary problem for a class of multidimensional generalized system of ferro-magnetic chain type is considered.
基金Supported by the National Natural Science Foundation of China under Grant Nos 11271168 and 11671177the Priority Academic Program Development of Jiangsu Higher Education Institutionsthe Innovation Project of the Graduate Students in Jiangsu Normal University
文摘The exact solutions of a chain of type Ⅱ are investigated. The chain of type Ⅱ is first transformed to an integrable differential-difference equation, which has the Kaup Newell spectral problem as its continuous spatial spectral problem and a Darboux transformation of the Kaup-Newell equation as its discrete temporal spectral problem. Then, with these spectral problems, a Darboux transformation of the transformed equation is constructed. Finally, as an application of the Darboux transformation, an exact solution of the transformed equation and thus the chain of type Ⅱ are presented.
文摘Ta_4(Te_2)_4Te_4I,Mr=2381.90,Monoclinic,C2/c,a=21.987(2),b=6.153(2),c= 19.936(3),β=122.42(14),V=2276.7 ~3,z=4,Dm=6.8(5)g/cm^3,Dc=6.95g/cm^3,λ(Mok)= 0.71073,μ=354.0cm^(-1),F(000)=3876,T=296(1)k,R=5.3%,Rw=6.8%,for 1118 unique observed reflections(1>3σ(Ⅰ)).The structure is composed of [Ta_4(Te_2)_4Te_4I]_∞~ chains,which are formed by the four-nuclear butterfly cluster units "Ta_4(Te_2)_4Te_4" with the Ⅰ atoms as the bridging atoms between different cluster units.
文摘The glomerulonephritis disease is characterized by inflammation of glomeruli or small blood vessels in the kidney that causes kidney diseases. The reason of glomerulonephritis disease is to deposit the anti-GBM auto antibody in the glomerular basement membrane. The type IV collagen is the main component of glomerular basement membrane that has α3 chain of type (IV) collagen of non-collagenous domain which contains N-terminal 7S domain, a triple helical collagenous domain and C-terminal non-collagenous glomerular domain (NC1). The amino terminal of α3 (IV) NC1 that induces the Experimental Autoimmuno Glomerulonephritis (EAG) in rat model has been identified. The recombinant rat α3 (IV) NC1 antigen has nine amino acid spans that are consistent with antibody or T cell epitope that induces in EAG. The research is carried out on the recombinant rat α3 (IV) NC1 production, purification, quantification, and characterization. The circulation of anti-GBM antibody in glomerular basement membrane can be measured by the ELISA assay. In addition, the recombinant rat antigen is secreted in HEK293 cell supernatant that is purified by Anti-FLAG M2 monoclonal IgG antibody affinity column and characterized and quantified by SDS-PAGE gel electrophoresis and Western blotting techniques.
基金supported by the National Natural Science Foundation of China (Grant No. 11205162)
文摘Based on space-charge wave theory, the formulae of the beam-wave coupling coefficient and the beam-loaded conductance are given for the beam-wave interaction in an N-gap Hughes-type coupled cavity chain. The ratio of the nonbeam-loaded quality factor of the coupled cavity chain to the beam quality factor is used to determine the stability of the beam-wave interaction. As an example, the stabilities of the beam-wave interaction in a three-gap Hughes-type coupled cavity chain are discussed with the formulae and the CST code for the operations of the 2π, π, and π/2 modes, respectively. The results show that stable operation of the 2π, π, and π/2 modes may all be realized in an extended-interaction klystron with the three-gap Hughes-type coupled cavity chain.
文摘A novel side chain liquid crystalline polymer (SCLCP) combining the polysiloxane as main chain with azo-based mesogen moieties as side chain through a flexible spacer has been synthesized by the hydrosilylation reaction using Cp_2PtCl_2 as catalyst. The phase transition behavior of both side chain monomer (AZO-C_6C_(11))and polymer (P-AZO-C_6C_(11))has been characterized via combination of hot-stage polarized microscope, DSC and X-ray diffraction methods (including temperature-variation and quenching techniques). As normal, the transition process included K→S→N→I. Some pretransition features have been observed.
基金Project (No.491030-w10011) supported by the Zhejiang Provincial Natural Science Foundation of China
文摘Background and objective:Botulinum toxin type A(BoNT/A)is a metalloprotease that blocks synaptic transmission via the cleavage of a synaptosomal-associated protein of 25 kDa(SNAP-25).It has gained widespread use as a treatment for cerebral palsy and skeletal muscle hypertrophy.In China,Chinese botulinum toxin type A(CBTX-A),a type of BoNT/A,is in widespread clinical use.However,the changes in the morphological and biochemical properties of treated muscles and in remote muscles from the CBTX-A injection site are relatively unknown.Therefore,we investigated the changes in histomorphology and myosin heavy chain(MyHC)isoform composition and distribution in rat gastrocnemius muscles after intramuscular injection of CBTX-A.Methods:The weakness of the injected muscles was assessed periodically to identify their functional deficiency.Muscle slices were stained with hematoxylin-eosin(HE)and adenosine triphosphatase(ATPase).MyHC isoform composition was analyzed by sodium dodecyl sulfatepolyacrylamide gel electrophoresis(SDS-PAGE)to uncover changes in morphological and biochemical properties.Results:Our findings demonstrate that following injection of CBTX-A 5 U into rat gastrocnemius muscles,shifts in MyHC isoform composition emerged on the third day after injection and peaked in the fourth week.The composition remained distinctly different from that of the control group after the twelfth week.More specifically,there was a decrease in the proportion of the type IIb isoform and an increase in the proportions of type IIx,type IIa,and type I isoforms.Conclusions:Data revealed that CBTX-A led to a shift in MyHC composition towards slower isoforms and that the MyHC composition remained far from normal six months after a single injection.However,no noticeable remote muscle weakness was induced.
文摘Amid the escalating plastic pollution issue, the development of biodegradable and recyclable polymeric materials has become a focus within the scientific community. Chain extenders, which are an important class of compounds, facilitate the elongation of polymer chains through reactive functional groups, thereby enhancing the performance of the materials. Epoxy-based chain extenders, due to their cost-effectiveness, low toxicity, high reaction efficiency, and effective reactivity with hydroxyl and carboxyl groups, have emerged as a promising class of chain extenders. This manuscript comprehensively elaborates on the varieties, structural characteristics, and performance of chain extenders, the challenges they face, and the methods for their modification. Special emphasis is placed on the application of epoxy-based chain extenders in biodegradable polymers, such as polylactic acid (PLA), and their subsequent influence on the structural and performance properties of these materials.
基金National Natural Science Foundation of China(No.50905075)the Six Talent Peaks Project in Jiangsu Province,China(No.ZBZZ-012)+4 种基金the Fundamental Research Funds for the Central Universities,China(No.JUSRP51316B)the Open Project of the State Key Laboratory of Mechanical System and Vibration of China(No.MSV201407)the Open Project of the Key Laboratory of System Control and Information Processing,China(No.Scip201506)the Open Project of Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment and Technology,China(No.FM-201402)the Research and the Innovation Project for College Graduates of Jiangsu Province,China(No.KYLX-1115)
文摘To avoid the existence of nonlinear and strong coupling in parallel mechanisms,it is necessary to address special care to the type synthesis of mechanisms,especially for the type synthesis of fully-decoupled parallel mechanisms. Based on the screw theory and the driven-chain principle,a methodology of structural synthesis for fully-decoupled three-rotational( 3R) and two-translational( 2T)parallel mechanisms was proposed by analyzing the characteristics of the input-output relations for fully-decoupled parallel mechanisms.Firstly,according to the desired kinematic characteristics of fullydecoupled parallel mechanisms,a method was presented by virtue of screw theory to synthesize the desired forms for both the direct and the inverse Jacobian matrices. Secondly,according to the feature of the direct and the inverse Jacobian matrices,the effective screws,the actuated screws and the mobile un-actuated screws of each leg were established based on the reciprocal screw theory and all possible topology structures fulfilling the requirements were obtained.Finally,the desired fully-decoupled parallel mechanisms could be synthesized by using the structural synthesis rule and structural synthesis of fully-decoupled 3R2 T parallel mechanisms could be obtained exploiting the abovementioned methodology. Furthermore,the Jacobian matrix of a synthesized 3R2 T parallel mechanism was deduced to demonstrate the decoupling feature of the parallel mechanism,which also validated the correctness of the methodology of the type synthesis for fully-decoupled 3R2 T parallel mechanisms.
