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Study on the Effects of National Volume-Based Procurement of Chemical Drugs on Chinese Patent Medicines:Lipid-Lowering Drugs as an Example
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作者 Zhao Yang Xiao Han +5 位作者 Pei Liang Xiaoting Zhao Qiyun Zhu Hui Ye Chao Yang Bin Jiang 《Health Care Science》 2025年第1期14-24,共11页
Background:Atherosclerotic cardiovascular disease remains the leading cause of death worldwide.This study aims to explore the impact of national volume-based procurement(NVBP)on Chinese patent medicines and provide ev... Background:Atherosclerotic cardiovascular disease remains the leading cause of death worldwide.This study aims to explore the impact of national volume-based procurement(NVBP)on Chinese patent medicines and provide evidence for improving policies and promoting rational drug use.Methods:The study was based on data from the China National Health Insurance Agency that spanned January 2019 to December 2020.Descriptive analysis was conducted using volume and expenditure as variables.Interrupted time series analysis was applied to further analyze Chinese patent medicines.Results:The unit prices of atorvastatin and rosuvastatin decreased by 25%-96%,whereas the prices of Zhibitai and Xuezhikang fluctuated slightly.The affordability is measured as the monthly expenditure on treatment divided by the daily wage.After policy implementation,the affordability of atorvastatin and rosuvastatin improved from 0.242 to 0.014 and from 0.247 to 0.019,respectively.The defined daily doses(DDDs)for atorvastatin and rosuvastatin also increased,whereas total expenditures decreased in hospitals of all levels.Both at the national level and at all levels of hospital,the policy had no significant impact on expenditures for Zhibitai and Xuezhikang and their defined daily doses.Conclusions:The NVBP saved costs in the short term by incorporating high-quality,widely used lipid-lowering drugs.Notably,the policy impacted lipid-lowering chemical drugs,whereas Chinese patent medicines remained largely unaffected.Doctors'use of Chinese patent medicines did not decline,highlighting the clinical specificity of these medicines. 展开更多
关键词 Chinese patent medicine health policy lipid-lowering drugs national volume-based procurement
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Quantitative Analysis of the Policy of Centralized Drug Procurement Based on PMC Index Model
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作者 Duan Xiaoxiang Wang Shuling 《Asian Journal of Social Pharmacy》 2025年第3期222-235,共14页
Objective To quantitatively analyze the policy of centralized drug procurement centralized drug procurement in order to provide reference for the subsequent policy formulation and improvement.Methods Text mining metho... Objective To quantitatively analyze the policy of centralized drug procurement centralized drug procurement in order to provide reference for the subsequent policy formulation and improvement.Methods Text mining method was used to process 15 centralized drugs procurement policies issued at the national level during 2015-2022,and a PMC index evaluation model of centralized drug procurement policies was established.Then,15 centralized drug procurement policies were quantitatively analyzed from the overall and comparative perspective through an evaluation model.Results and Conclusion The average PMC index of 15 centralized drug procurement policies was 6.95,which was acceptable on the whole.Among them,eight were excellent and seven were acceptable.As to the first-order variables,the centralized drugs procurement policy still lacks incentives and constraints.The comparative results show that there are differences in the content and structure of policies,but they are strongly related to each other.Chinese centralized drug procurement policy has been basically formed,which is closely related to medical insurance and medical policies.However,it is still necessary to pay attention to the structure of the policy to ensure the elaboration of the policy content. 展开更多
关键词 centralized drug procurement PMC index POLICY quantitative analysis
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Construction of Evaluation Index System for the Policy Effect of Centralized Drug Procurement
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作者 Huang Jiaxin Raela·Abduhilil +2 位作者 Hu Ping Liu Xinying Sun Lihua 《Asian Journal of Social Pharmacy》 2025年第4期313-324,共12页
Objective To construct an index system for evaluating the policy effect of centralized drug procurement,and to provide reference for comprehensively and systematically evaluating the policy of centralized drug procure... Objective To construct an index system for evaluating the policy effect of centralized drug procurement,and to provide reference for comprehensively and systematically evaluating the policy of centralized drug procurement.Methods Through combing the policies and literature research,the focus and expected goal of China’s centralized drug procurement policy were clarified.On the basis of policy concerns,combined with some theories and the implementation of drug centralized procurement policy,a primary evaluation index system was constructed.The index system was determined by expert consultation,and the weight of each index was calculated by analytic hierarchy process.Results and Conclusion The questionnaire recovery rates of the two rounds of expert consultation were 88.23%and 100%,the coefficients of authority of experts were 0.86 and 0.80,and the expert coordination coefficients were 0.338 and 0.294,respectively.Finally,the evaluation index system for the policy of centralized drug procurement was established,which included 4 first-level indicators,10 second-level indicators and 23 third-level indicators.The evaluation index system constructed in this paper can not only make up for the deficiency of systematic evaluation of the policy effect of the current centralized drug procurement,but also provide reference for further improving this policy. 展开更多
关键词 centralized drug procurement STAKEHOLDER policy evaluation
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The Management Practice and Reflection of Centralized Drug Procurement in Hospitals
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作者 Yuchen Li 《Proceedings of Business and Economic Studies》 2025年第3期54-59,共6页
The centralized procurement of drugs in the medical system is a key link,which not only affects the economic effect of institutions,but also relates to the medical quality and patient safety.In the current era,central... The centralized procurement of drugs in the medical system is a key link,which not only affects the economic effect of institutions,but also relates to the medical quality and patient safety.In the current era,centralized drug procurement in hospitals can meet the needs of most patients;however,the specific steps of the work still need to be optimized.Starting from the level of hospital drug centralized procurement work,this paper discusses the policy background,analyzes the practice of drug centralized procurement in tertiary hospitals,and provides specific work management suggestions,aiming to improve work efficiency and serve as a reference for optimizing subsequent hospital drug centralized procurement work. 展开更多
关键词 Hospital drugs centralized procurement work Management practice Suggestions
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Application Value of PDCA in Hospital Centralized Procurement Quality Management
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作者 WU Guixin 《外文科技期刊数据库(文摘版)医药卫生》 2021年第7期047-049,共5页
Objective: to analyze the application value of PDCA (Plan-do-check-act) management model in hospital centralized procurement quality management. Methods: from January 2019 to June 2020, our hospital began to apply PDC... Objective: to analyze the application value of PDCA (Plan-do-check-act) management model in hospital centralized procurement quality management. Methods: from January 2019 to June 2020, our hospital began to apply PDCA management model to the quality management of hospital centralized procurement. By using the basic process of planning-implementation-inspection-improvement, and establishing and further optimizing the procurement organization at the organizational level, further formulating and revising the procurement system for the procurement system, centralized procurement and organizing bidding at the operational level. Results: through the application of PDCA management mode, the procurement process can be optimized and necessary optimization can be made for the procurement process, with a significant overall effect. Through the application of PDCA, the procurement task was completed to 100%, and the procurement cost was saved by more than 11.70%, while the quality and satisfaction of the hospital demand department to the purchased products reached 99.67%. Conclusion: the application of PDCA management model in hospital centralized procurement is particularly critical to improve the quality of procurement, which can achieve the objectives of saving procurement costs, improving the quality of purchased products and procurement satisfaction. 展开更多
关键词 PDCA management model centralized procurement procurement costs procurement quality procurement
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Analysis on the Mode of Centralized Material Procurement of Group City Gas Enterprises
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作者 CAO Qili 《外文科技期刊数据库(文摘版)经济管理》 2021年第11期121-124,共6页
With the continuous development of the domestic natural gas market and the increasing trend of group operation of city gas enterprises, each large and medium-sized gas group enterprise cannot achieve cost reduction, e... With the continuous development of the domestic natural gas market and the increasing trend of group operation of city gas enterprises, each large and medium-sized gas group enterprise cannot achieve cost reduction, efficiency improvement and market competitiveness without an efficient centralized procurement system. However, the centralized procurement mode of gas enterprises has gradually deepened from the simple bundle procurement to the standardized and scientific centralized procurement supply chain mode. Based on the summary and analysis of the material centralized purchase mode of a medium-sized city gas group in recent ten years, this paper further explores the idea of the construction of centralized purchase supply chain. 展开更多
关键词 city gas group centralized procurement of materials centralized procurement supply chain
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Strategic Research on Pharmaceutical Enterprises’ Participation in National Drug Centralized Procurement
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作者 Yang Dianzheng Xu Wenxiu +1 位作者 Qi Yun Yang Yue 《Asian Journal of Social Pharmacy》 2022年第1期15-22,共8页
Objective To study the influence of national drug centralized procurement policy on pharmaceutical enterprises manufacturing generic drugs and original drugs,so as to provide a reference for them to make different str... Objective To study the influence of national drug centralized procurement policy on pharmaceutical enterprises manufacturing generic drugs and original drugs,so as to provide a reference for them to make different strategic choices.Methods Through the literature research on the related policies and the bidding data,the national drug centralized policies were studied systematically.Combined with the bid-winning price and price reduction range of the winning enterprises in the three rounds of centralized procurement,their difficulties,strategic choices and the winning factors were investigated.Besides,a model was established to clarify the optimal price of enterprises in the process of drug procurement.Results and Conclusion The strategic choices of enterprises in participating national drug centralized procurement are influenced by many factors such as the market share of the original varieties,active pharmaceutical ingredients(APIs)and cost.Therefore,corresponding strategies should be formulated according to the characteristics and interests of enterprises. 展开更多
关键词 drug centralized procurement pharmaceutical enterprises GAME STRATEGY
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The Establishment of Management Mode of Centralized Procurement
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作者 CHEN Keren DU Ping 《外文科技期刊数据库(文摘版)经济管理》 2021年第8期052-055,共6页
In order to implement the relevant provisions of the State-owned Assets Supervision and Administration Commission on the benchmarking of procurement management, improve the effectiveness of procurement, reduce procure... In order to implement the relevant provisions of the State-owned Assets Supervision and Administration Commission on the benchmarking of procurement management, improve the effectiveness of procurement, reduce procurement costs and control the risks of integrity in procurement, the Group Company will step by step promote centralized procurement, build a centralized procurement management system for the Group Company, build an information system for centralized procurement management, give full play to the advantages of overall procurement, strengthen implementation supervision, form a sustainable long-term mechanism for centralized procurement, promote the overall improvement of the procurement management capabilities of units at all levels of the Group Company, and organize member units and subordinate units to implement centralized and unified external procurement of materials, projects and services included in the centralized procurement catalog. The Company adheres to the principle of "overall management and control, platform operation, supervision and balance, intensive and efficient", implements the requirements of the Group Company from the aspects of organizational structure and functions, contract signing methods, business processes, data statistics and analysis, supplier management, inspection and supervision, assessment and evaluation, and establishes a centralized procurement management model. The unit and its subordinate units will hand over the items in the centralized procurement catalog to the centralized procurement platform for unified negotiation and procurement, which will bring into play the economies of scale, save procurement costs, simplify procurement process, reduce procurement risks and improve procurement efficiency. 展开更多
关键词 centralized procurement management system signing of contracts supplier management
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Suggestions on Foreign Pharmaceutical Enterprises Dealing with China’s Drug Centralized Procurement - Taking the First Batch of Implementation Results as an Example
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作者 Li Yunlong Ning Bowen Yuan Hongmei 《Asian Journal of Social Pharmacy》 2022年第1期23-33,共11页
Objective To analyze the impact of the first batch of centralized drug procurement on foreign pharmaceutical enterprises since the national centralized drug procurement policy has brought great impact on pharmaceutica... Objective To analyze the impact of the first batch of centralized drug procurement on foreign pharmaceutical enterprises since the national centralized drug procurement policy has brought great impact on pharmaceutical market,and put forward some suggestions on their marketing transformation in China.Methods Firstly,the documents of the drug centralized procurement were studied,and then the sales figures before and after the implementation of the policy were retrieved from MiNET.At the same time,the relevant business adjustment information of foreign pharmaceutical enterprises was collected for analysis.Results and Conclusion The sales of related products of foreign pharmaceutical enterprises have dropped sharply,so they have stripped off these products and reduced their staff.It is suggested that foreign pharmaceutical enterprises should adjust the structure of sales team,strengthen the layout of the market in the county,and accelerate the introduction of innovative drugs to cope with centralized drug procurement. 展开更多
关键词 centralized procurement foreign pharmaceutical enterprise drug price MARKETING REFORM
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Analysis on the Application of Information Technology in the Centralized Procurement Management of Modern Enterprise Materials
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作者 MENGXiangsheng 《外文科技期刊数据库(文摘版)经济管理》 2022年第6期017-020,共4页
In the process of production and operation of modern enterprises, material procurement management is a necessary basic link in production. However, due to the limitations of management methods and technical means, inf... In the process of production and operation of modern enterprises, material procurement management is a necessary basic link in production. However, due to the limitations of management methods and technical means, information technology has certain deficiencies in the centralized material procurement management of modern enterprises, which has a relatively intuitive impact on the centralized material procurement management. Therefore, this paper takes the practical application of information technology in the centralized procurement management of modern enterprise materials as the breakthrough point, and fully analyzes the significance of information technology in the production, operation and management of modern enterprises. At the same time, it makes judgment and observation on the practical problems existing in the application of information technology in the centralized procurement management of materials as the main research content, so as to put forward targeted countermeasures and management methods, so as to ensure the orderly development of the centralized procurement management of materials in modern enterprises and lay a solid foundation for the stable development of subsequent enterprises. 展开更多
关键词 information technology modern enterprise centralized procurement management of materials
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仿制与原研利奈唑胺葡萄糖注射液临床疗效比较
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作者 王之舟 王可 +6 位作者 邢晓璇 花一鸣 张晓彤 李晓曦 冯英楠 董宪喆 张兰 《中国抗生素杂志》 北大核心 2026年第2期227-234,共8页
目的比较集采中选仿制与原研利奈唑胺葡萄糖注射液治疗细菌感染的临床疗效,为国家组织集采中选利奈唑胺葡萄糖注射液的临床使用及效果评价提供真实世界证据。方法回顾性收集首都医科大学宣武医院在2019年1月—2023年6月期间使用集采中... 目的比较集采中选仿制与原研利奈唑胺葡萄糖注射液治疗细菌感染的临床疗效,为国家组织集采中选利奈唑胺葡萄糖注射液的临床使用及效果评价提供真实世界证据。方法回顾性收集首都医科大学宣武医院在2019年1月—2023年6月期间使用集采中选仿制或原研利奈唑胺葡萄糖注射液治疗成人细菌感染患者的诊疗资料。采用1:1倾向性评分匹配法平衡了组间人口统计学特征、合并症、感染类型及其严重程度、合并用药和治疗等关键指标。对集采中选仿制组和原研组患者的住院期间生存情况、28 d感染治疗成功率、3 d体温恢复率、换药率、住院时间以及治疗后体温和实验室检查指标的变化进行了比较分析。结果共纳入485例使用集采中选仿制或原研利奈唑胺葡萄糖注射液的患者,1:1匹配后每组各155例。集采中选仿制组较原研组住院死亡风险比(HR0.848,95%CI:0.51~1.40,P=0.530)及住院全因死亡率(18.7%vs 21.3%,P=0.670)均未达到统计显著性。在28 d感染治疗成功率(72.9%vs 63.9%)、3 d体温恢复率(88.2%vs 82.9%)、换药率(8.4%vs 12.9%)以及平均住院时间(27.76 d vs 29.61 d)方面,组间差异均无统计显著性(P>0.05)。利奈唑胺葡萄糖注射液治疗后体温和实验室检查值分布相似,组间差异不具有临床意义。结论集采中选仿制利奈唑胺葡萄糖注射液与原研药在治疗成人细菌感染方面临床疗效相当。 展开更多
关键词 国家集中带量采购 利奈唑胺 仿制药 原研药 疗效 抗菌药物
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集采与原研布地奈德联合特布他林辅助治疗儿童支气管肺炎有效性、安全性和经济性评价
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作者 汪江涛 蒋慧莲 +3 位作者 叶鸣 方佳 赵磊 丁伯平 《中国药业》 2026年第4期132-135,共4页
目的评价集中带量采购(以下简称集采)与原研吸入用布地奈德混悬液(以下简称布地奈德)联合硫酸特布他林雾化吸入用溶液(以下简称特布他林)辅助治疗儿童支气管肺炎的有效性、安全性和经济性。方法选取医院2023年1月至2024年6月收治的儿童... 目的评价集中带量采购(以下简称集采)与原研吸入用布地奈德混悬液(以下简称布地奈德)联合硫酸特布他林雾化吸入用溶液(以下简称特布他林)辅助治疗儿童支气管肺炎的有效性、安全性和经济性。方法选取医院2023年1月至2024年6月收治的儿童支气管肺炎患儿160例,根据辅助药物来源的不同,分为集采组和原研组,各80例。两组患儿均予常规治疗和布地奈德联合特布他林雾化吸入辅助治疗,比较两组患儿的病情改善时间(含体温恢复时间、咳嗽消失时间、气喘消失时间、肺部罗音消失时间)、住院时间、临床疗效、药品不良反应(ADR)发生情况,并使用成本-效果比(C/E)评价药物经济性。结果有效性方面,集采组与原研组总有效率相当(96.25%比97.50%,P>0.05),且两组患儿病情改善时间和住院时间比较均无显著差异(P>0.05);安全性方面,集采组与原研组ADR发生率相当(8.75%比7.50%,P>0.05);经济性方面,集采组药物C/E值为0.67±0.06,显著低于原研组的2.52±0.24,且成本波动±10%时,集采组药物C/E值仍显著低于原研组(P<0.001)。结论集采和原研布地奈德联合特布他林雾化吸入辅助治疗儿童支气管肺炎的有效性和安全性相当,但集采药品经济性更好。 展开更多
关键词 药品集中带量采购 布地奈德 特布他林 支气管肺炎 患儿 综合评价
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国家组织药品集中采购政策下奥氮平片中标药与原研药的真实世界研究
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作者 刘珊珊 李婕 +1 位作者 王斌 任艳萍 《中国现代医药杂志》 2026年第3期13-18,共6页
目的评估国家组织药品集中采购政策下奥氮平片中选仿制药与原研药的疗效与安全性差异,以及该政策对医生处方行为和患者治疗费用的影响。方法采用回顾性队列研究设计,收集北京某三甲精神专科医院2020年4~10月(集采前)和2024年4~10月(集采... 目的评估国家组织药品集中采购政策下奥氮平片中选仿制药与原研药的疗效与安全性差异,以及该政策对医生处方行为和患者治疗费用的影响。方法采用回顾性队列研究设计,收集北京某三甲精神专科医院2020年4~10月(集采前)和2024年4~10月(集采后)使用奥氮平治疗的住院患者数据。比较集采中选仿制药(欧兰宁^(®))与原研药(再普乐^(®))在临床总体印象严重程度量表(CGI-S)、阳性和阴性症状量表(PANSS)评分变化、代谢指标异常发生率及药品费用等方面的差异。结果共纳入1856例患者,其中仿制药组1132例,原研药组724例。治疗结束后,两组主要疗效指标无显著统计学差异(P>0.05),临床缓解率相当(仿制药组81.7%vs.原研药组82.5%,P=0.624)。不良反应总体发生率相似(仿制药组25.8%vs.原研药组26.3%,P=0.782)。仿制药组药品费用显著低于原研药组(P<0.01)。结论集采中选的奥氮平仿制药与原研药在真实世界临床应用中疗效和安全性相当,且能显著降低患者经济负担。 展开更多
关键词 药品集中采购 奥氮平 仿制药 原研药 真实世界研究 精神分裂症
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口腔种植系统集中带量采购实施效果分析及建议
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作者 高燕华 杜广智 +2 位作者 赵莹颖 吴春旭 范宝林 《医院管理论坛》 2026年第1期38-41,共4页
分析某三级专科医院的口腔种植系统集中带量采购的实施情况,通过总结取得的效果及执行中出现的问题,提出思考及建议。旨在建立医院长效管理机制,构建科学管理体系,促进集中带量采购医用耗材的合理使用,从而达到持续加强医用耗材集中带... 分析某三级专科医院的口腔种植系统集中带量采购的实施情况,通过总结取得的效果及执行中出现的问题,提出思考及建议。旨在建立医院长效管理机制,构建科学管理体系,促进集中带量采购医用耗材的合理使用,从而达到持续加强医用耗材集中带量采购管理的目的,为迎接其他医用耗材的集中带量采购工作提供有益借鉴,推动医院高质量发展。 展开更多
关键词 口腔种植系统 集中带量采购 医用耗材价格
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集采背景下中药饮片浙贝母的质量分级探索性研究
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作者 刘立权 王鑫昱 +2 位作者 吕兰 王姝静 吴敏 《医学研究前沿》 2026年第1期129-132,共4页
目的基于外在形态和内在质量建立浙贝母饮片的质量分级标准。方法对采集的浙贝母饮片20批样品,运用水分、醇浸出物、水浸出物、有效成分含量、饮片直径5个主要的质量指标开展描叙统计分析、相关性分析以及主成分分析等工作探索合理可行... 目的基于外在形态和内在质量建立浙贝母饮片的质量分级标准。方法对采集的浙贝母饮片20批样品,运用水分、醇浸出物、水浸出物、有效成分含量、饮片直径5个主要的质量指标开展描叙统计分析、相关性分析以及主成分分析等工作探索合理可行的质量分级方法。结果不同批次浙贝母饮片的质量差异很大,醇浸出物的含量在19.50%~45.30%之间,水浸出物含量在25.10%~36.50%之间,两者间有很强的负相关关系(r=-0.94);饮片直径与有效成分含量呈显著负相关(r=-0.57,P<0.05);主成分分析显示,水浸出物和有效成分含量是影响浙贝母饮片质量的两大主因子,二者决定着浙贝母饮片整体质量。结论制定集采场景下浙贝母的质量三级分级标准。 展开更多
关键词 药品集中采购 浙贝母 中药饮片 质量分级 浸出物
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某妇幼专科医院国家集采抗菌药物使用情况分析
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作者 张杜娟 李国辉 李国庆 《中国药业》 2026年第4期41-45,共5页
目的分析国家组织药品集中带量采购(以下简称集采)政策对某妇幼专科医院抗菌药物使用的影响。方法统计医院抗菌药物集采前后1年的药品名称、规格、生产企业、价格、用量及使用金额等基本信息,分析其变化,并计算以上药物的用药频度(DDDs... 目的分析国家组织药品集中带量采购(以下简称集采)政策对某妇幼专科医院抗菌药物使用的影响。方法统计医院抗菌药物集采前后1年的药品名称、规格、生产企业、价格、用量及使用金额等基本信息,分析其变化,并计算以上药物的用药频度(DDDs)、限定日费用(DDC)及实际节省费用。结果共纳入6批(第二、三、四、五、七、八批)23种国家集采抗菌药物。与集采前比较,集采后20个品种价格下降,以奥硝唑注射剂降幅最大(96.40%),氨曲南注射剂降幅最小(11.71%),3个品种(头孢唑林注射剂、头孢呋辛注射剂和氟康唑注射剂)价格上涨(>500%);17个品种集采后药物用量及DDDs下降,以氨曲南注射剂降幅最大(均为100.00%),6个品种升高,以哌拉西林他唑巴坦注射剂升幅最大(154.74%);除头孢唑林注射剂、头孢呋辛注射剂、氟康唑注射剂升高外,其余品种的使用金额及DDC均下降;实际节省费用以哌拉西林他唑巴坦注射剂最多(2398077.38元),所有集采品种共计节省费用6925021.24元。结论集采后,该院大部分抗菌药物用量和DDDs,以及使用金额和DDC均不同程度降低,有效减轻了患者和社会的经济负担。 展开更多
关键词 国家药品集中带量采购 抗菌药物 用药频度 限定日费用
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基于真实世界数据的11个试点城市阿托伐他汀与瑞舒伐他汀国家集采政策效果评价——间断时间序列分析
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作者 史锦仕 陈雯 +1 位作者 江滨 易湛苗 《中国医院药学杂志》 北大核心 2026年第2期159-166,共8页
目的:明确国家组织药品集中带量采购政策对11个试点城市阿托伐他汀、瑞舒伐他汀采购金额及用药频度的影响,科学评价该政策实施效果。方法:基于国家医保局集采数据系统,采用间断时间序列分析评估政策实施前后药品的月度采购金额和用药频... 目的:明确国家组织药品集中带量采购政策对11个试点城市阿托伐他汀、瑞舒伐他汀采购金额及用药频度的影响,科学评价该政策实施效果。方法:基于国家医保局集采数据系统,采用间断时间序列分析评估政策实施前后药品的月度采购金额和用药频度变化。结果:试点后,阿托伐他汀未中选原研药、中选仿制药、未中选过评仿制药的采购金额瞬时水平均显著下降(β_(2)=-14139.96,P<0.01;β_(2)=-2404.78,P=0.065;β_(2)=-1914.92,P<0.01)。对于用药频度,中选仿制药的瞬时水平显著上升(β_(2)=2403.21,P<0.01),且呈上升的变化趋势(β_(3)=76.96,P=0.119),原研药和未中选过评仿制药的瞬时水平均显著下降(β_(2)=-1847.91,P<0.01;β_(2)=-272.57,P<0.01)。瑞舒伐他汀的3类药品采购金额瞬时水平均显著下降(原研:β_(2)=-1120.27,P=0.012;中选仿制:β_(2)=-565.87,P=0.309;未中选过评仿制:β_(2)=-2049.11,P<0.01),中选仿制药用药频度瞬时水平显著上升(β_(2)=1132.83,P=0.004),原研药和未中选过评仿制药用药频度瞬时水平均显著下降(原研:β_(2)=-94.75,P=0.080;未中选过评仿制:β_(2)=-272.57,P<0.01)。结论:国家药品集采政策可优化他汀类药品采购结构,提升中选仿制药可及性,降低患者用药负担与医保支出,实现控费目标。 展开更多
关键词 集中采购 阿托伐他汀 瑞舒伐他汀 间断时间序列 政策效果
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广西医疗机构集中带量采购药品遴选实施与管理专家共识
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作者 李婷婷 周甘平 +3 位作者 陈燕青 吴冬妮 唐微艳 张宏亮 《中国药房》 北大核心 2026年第7期829-834,共6页
目的制定《广西医疗机构集中带量采购药品遴选实施与管理专家共识》(下文简称《共识》),为广西各级医疗机构集中带量采购(下文简称“集采”)药品遴选与管理提供决策支持与实践指导。方法系统梳理广西既往执行药品集采的各批次材料,全面... 目的制定《广西医疗机构集中带量采购药品遴选实施与管理专家共识》(下文简称《共识》),为广西各级医疗机构集中带量采购(下文简称“集采”)药品遴选与管理提供决策支持与实践指导。方法系统梳理广西既往执行药品集采的各批次材料,全面检索药品相关著作、书籍,系统梳理药品遴选相关指南、集采药品专家共识及政策文件等资料,通过召开3轮专题研讨会,结合现有循证依据及各级医疗机构实际遴选经验,经充分讨论、逐轮修订,最终形成《共识》。结果与结论《共识》系统梳理了医疗机构遴选集采药品过程的3个关键阶段——采购需求量填报、协议采购量确认、采购与使用落地;围绕规格、剂型、包装、装量及生产企业等多个维度提出集采药品遴选策略;针对集采药品遴选实践中的现实挑战,提出建立常态化信息储备机制、强化信息技术支持、实施分类遴选等应对策略;倡导医疗机构构建政策、数据与质量“三位一体”的决策体系,推进集采药品全周期管理。本《共识》将为广西各级医疗机构科学开展集采药品遴选工作提供实践指导,助力推动集采政策在医疗机构的平稳落地与持续健康发展。 展开更多
关键词 集中带量采购 药品遴选 药品管理 医疗机构 广西 专家共识
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我国医用耗材集采政策对患者住院费用影响的系统评价和Meta分析
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作者 沈斐汉 罗棋尹 +6 位作者 杨珍珍 张亚杰 郭妮 娄文慧 宋旭萍 杨克虎 White Howard 《中国循证医学杂志》 北大核心 2026年第2期166-171,共6页
目的系统评价医用耗材集采政策对我国患者住院费用的影响。方法计算机检索PubMed、Web of Science核心合集、Scopus、CNKI、CBM和WanFang Data数据库,搜集医用耗材集采政策对我国患者住院费用影响的相关研究,检索时限均为2000年1月1日至... 目的系统评价医用耗材集采政策对我国患者住院费用的影响。方法计算机检索PubMed、Web of Science核心合集、Scopus、CNKI、CBM和WanFang Data数据库,搜集医用耗材集采政策对我国患者住院费用影响的相关研究,检索时限均为2000年1月1日至2025年5月13日。由2名研究者独立筛选文献、提取资料并评价纳入研究的偏倚风险后,使用Stata 17.0软件进行Meta分析。结果Meta分析结果显示:医用耗材集采政策实施后患者次均住院总费用下降[SMD=-4.754,95%CI(-7.434,-2.075),P<0.001];亚组分析结果显示冠状动脉支架(冠脉支架)[SMD=-0.721,95%CI(-1.040,-0.402),P<0.001]和人工晶体[SMD=-0.660,95%CI(-0.984,-0.337),P<0.001]集采后患者次均住院总费用均下降,人工关节集采后患者次均住院总费用降幅较大[SMD=-10.344,95%CI(-15.147,-5.540),P<0.001]。结论我国从患者视角开展的医用耗材集采政策实施效果评估证据主要集中在经济发达省市,中等质量的证据表明人工关节集采后患者次均住院总费用降幅最大,冠脉支架和人工晶体集采政策实施后患者次均住院总费用均降低,建议未来进一步扩大集采范围。 展开更多
关键词 医用耗材 集采 患者住院费用 系统评价 META分析
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集中采购与非集中采购注射用美罗培南治疗细菌性感染的有效性和安全性比较
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作者 李妮妮 陆瑾 +1 位作者 蒙钟经 展冠军 《中国临床药学杂志》 2026年第2期151-155,共5页
目的 比较国家集中带量采购(集采)与非集采注射用美罗培南治疗细菌性感染的有效性和安全性。方法 采用回顾性队列研究。收集医院于2022年1月至2023年10月使用注射用美罗培南的集采品种(集采组)或非集采品种(非集采组)治疗细菌性感染患... 目的 比较国家集中带量采购(集采)与非集采注射用美罗培南治疗细菌性感染的有效性和安全性。方法 采用回顾性队列研究。收集医院于2022年1月至2023年10月使用注射用美罗培南的集采品种(集采组)或非集采品种(非集采组)治疗细菌性感染患者的病例资料,采用倾向性评分匹配(PSM)均衡混杂因素后,比较2组治疗的有效性和安全性。结果 匹配后,集采组和非集采组各纳入患者90例。有效性方面,集采组与非集采组的临床有效率、72 h有效率、细菌清除率,以及体温、中性粒细胞百分比、C反应蛋白和降钙素原恢复水平比较,差异均无统计学意义(P > 0.05),但集采组的白细胞(WBC)计数高于非集采组(P<0.05)。安全性方面,集采组的药品不良反应总发生率及实验室相关指标异常率与非集采组比较,差异均无统计学意义(P > 0.05)。结论 虽然集采组治疗后的WBC计数高于非集采组,但2组总体的有效性和安全性相当。 展开更多
关键词 集中带量采购 美罗培南 有效性 安全性
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