Objective Multiparametric magnetic resonance imaging(MRI)has become the standard of care for the diagnosis of prostate cancer patients.This study aimed to evaluate the influence of preoperative MRI on the positive sur...Objective Multiparametric magnetic resonance imaging(MRI)has become the standard of care for the diagnosis of prostate cancer patients.This study aimed to evaluate the influence of preoperative MRI on the positive surgical margin(PSM)rates.Methods We retrospectively reviewed 1070 prostate cancer patients treated with radical prostatectomy(RP)at Siriraj Hospital between January 2013 and September 2019.PSM rates were compared between those with and without preoperative MRI.PSM locations were analyzed.Results In total,322(30.1%)patients underwent MRI before RP.PSM most frequently occurred at the apex(33.2%),followed by posterior(13.5%),bladder neck(12.7%),anterior(10.7%),posterolateral(9.9%),and lateral(2.3%)positions.In preoperative MRI,PSM was significantly lowered at the posterior surface(9.0%vs.15.4%,p=0.01)and in the subgroup of urologists with less than 100 RP experiences(32%vs.51%,odds ratio=0.51,p<0.05).Blood loss was also significantly decreased when a preoperative image was obtained(200 mL vs.250 mL,p=0.02).Multivariate analysis revealed that only preoperative MRI status was associated with overall PSM and PSM at the prostatic apex.Neither the surgical approach,the neurovascular bundle sparing technique,nor the perioperative blood loss was associated with PSM.Conclusion MRI is associated with less overall PSM,PSM at apex,and blood loss during RP.Additionally,preoperative MRI has shown promise in lowering the PSM rate among urologists who are in the early stages of performing RP.展开更多
Background:The effectiveness and safety of marginal donor livers remain controversial.This study aimed to investigate the clinical efficacy of marginal donor livers in patients with liver transplantation(LT).Methods:T...Background:The effectiveness and safety of marginal donor livers remain controversial.This study aimed to investigate the clinical efficacy of marginal donor livers in patients with liver transplantation(LT).Methods:This study included 199 liver donors(including 16 split donors)and 206 liver recipients from January 1,2018 to January 27,2020,with case follow-up until July 31,2021.Clinical data of donors and recipients were retrospectively analyzed and were divided into the marginal donor and standard donor groups according to the criteria of marginal donor livers.Indices of liver and kidney functions,complications,and survival curves of the two groups were compared.Results:Compared with the standard donor group,the blood creatinine levels were significantly higher in the marginal donor group in the first week after operation(P<0.05);there were no significant differences in alanine aminotransferase,aspartate aminotransferase,and total bilirubin levels after LT(all P>0.05);there was no significant difference in the incidence of complications after LT(P>0.05);there was also no significant difference in the survival curve(P=0.335).Conclusions:There were no significant differences in liver and kidney function and survival curve between the standard donor and marginal donor groups.The marginal donor liver appears safe and reliable for LT and may be an important strategy to expand the donor pool and solve the shortage of organs.展开更多
The official unveiling of China Cultural Center in Bern signifies a new era of cultural exchange between China and Switzerland.The Center will serve as a vital platform for dialogue between Chinese and Swiss cultures.
Based on a set of high-resolution 3D seismic data from the northern continental margin of the South China Sea,the lithospheric structure,thinning mechanisms and related syn-rift tectonic deformation response processes...Based on a set of high-resolution 3D seismic data from the northern continental margin of the South China Sea,the lithospheric structure,thinning mechanisms and related syn-rift tectonic deformation response processes in the crustal necking zone in the deepwater area of the Pearl River Mouth Basin were systematically analyzed,and the petroleum geological significance was discussed.The necking zone investigated in the study is located in the Baiyun Sag and Kaiping Sag in the deepwater area of the Pearl River Mouth Basin.These areas show extreme crustal thinned geometries of central thinning and flank thickening,characterized by multi-level and multi-dipping detachment fault systems.The necking zone exhibits pronounced lateral heterogeneity in structural architectures,which can be classified into four types of thinned crustal architectures,i.e.the wedge-shaped extremely thinned crustal architecture in the Baiyun Main Sub-sag,dumbbell-shaped moderately thinned crustal architecture in the Baiyun West Sub-sag,box-shaped weakly thinned crustal architecture in eastern Baiyun Sag,and metamorphic core complex weakly thinned crustal architecture in the Kaiping Sag.This shows great variations in the degree and style of crustal thinning,types of detachment faults,distribution of syn-rift sedimentary sequences,and intensity of magmatism.The thinning of the necking zone is controlled by the heterogeneous rheological stratification of lithosphere,intensity of mantle-derived magmatism,and deformation modes of detachment faults.The syn-rift tectonic deformation of the necking zone evolved through three phases,i.e.uniform stretching during the early Wenchang Formation deposition period,necking during the late Wenchang Formation deposition period,and hyperextension during the Enping Formation deposition period.The crustal thinning extent and architectural differentiation in these phases were primarily controlled by three distinct mechanisms,i.e.the pure shear deformation activation of pre-existing thrust faults,the simple shear deformation of crust-mantle and inter-crust detachment faults,and differential coupling of lower crustal flow and ductile domes with main detachment faults.The hydrocarbon accumulation and enrichment in the necking zone exhibit marked spatial heterogeneity.Four distinct crustal thinned architecture-hydrocarbon accumulation models were identified in this study.The hydrocarbon accumulations in the shallow part exhibit significant correlations with their deep crustal thinned architectures.The unique lithospheric structure and deformation process predominantly control the favorable hydrocarbon accumulation zones with excellent source-fault-ridge-sand configurations,which is critical to reservoir-forming.The most promising exploration targets are mainly identified on the uplift zones and their seaward-dipping flanks associated with the middle and lower crustal domes.This research provides additional insights into lithospheric thinning-breakup process at intermediate continental margins of marine sedimentary basins,being significant for guiding the deepwater petroleum exploration in the Pearl River Mouth Basin.展开更多
Navigation satellites generally use satellite-ground and inter-satellite observation data for precise orbit determination.In orbit determination,the satellite position is often referenced to the satellite’s centroid,...Navigation satellites generally use satellite-ground and inter-satellite observation data for precise orbit determination.In orbit determination,the satellite position is often referenced to the satellite’s centroid,while the observational measurements are referenced to the satellite’s antenna phase center.The deviation between the satellite’s centroid and the antenna phase center forms the satellite antenna phase center error,which affects the precision of orbit determination.This paper takes a global navigation satellite system(GNSS)MEO satellite as an example and analyzes the actual situation of the satellite antenna phase center deviation and phase center variation based on the ground calibration data of the in-orbit satellite antenna phase center and the satellite’s in-orbit working status.The analysis shows that the antenna phase center variation caused by the satellite’s in-orbit operation is only at the centimeter level,which has a limited impact on orbit determination accuracy.The main source of precise orbit determination error is the satellite antenna phase center deviation,which can be corrected using ground calibration data.展开更多
Development of the telencephalon relies upon several signaling centers-localized cellular populations that supply secreted factors to pattern the cortical neuroepithelium.One such signaling center is the cortical hem,...Development of the telencephalon relies upon several signaling centers-localized cellular populations that supply secreted factors to pattern the cortical neuroepithelium.One such signaling center is the cortical hem,which arises during embryonic development at the telencephalic dorsal midline,adjacent to the choroid plexus and hippocampal primordium(Figure 1A).While the cortical hem has also been described in reptiles and birds,most of our knowledge about the developmental roles of the cortical hem is derived from the analysis in mice.The cortical hem produces several types of secreted molecules,including wingless-related integration site(Wnt)and bone morphogenetic(Bmp)proteins.The cortical hem is particularly important for the development of the hippocampus,which is involved in learning and memory,and the neocortex,which is the most complex brain region that mediates multiple types of behavior and higher cognitive functions(Mangale et al.,2008;Dal-Valle-Anton and Borrell,2022).展开更多
Air pollution in China covers a large area with complex sources and formation mechanisms,making it a unique place to conduct air pollution and atmospheric chemistry research.The National Natural Science Foundation of ...Air pollution in China covers a large area with complex sources and formation mechanisms,making it a unique place to conduct air pollution and atmospheric chemistry research.The National Natural Science Foundation of China’s Major Research Plan entitled“Fundamental Researches on the Formation and Response Mechanism of the Air Pollution Complex in China”(or the Plan)has funded 76 research projects to explore the causes of air pollution in China,and the key processes of air pollution in atmospheric physics and atmospheric chemistry.In order to summarize the abundant data from the Plan and exhibit the long-term impacts domestically and internationally,an integration project is responsible for collecting the various types of data generated by the 76 projects of the Plan.This project has classified and integrated these data,forming eight categories containing 258 datasets and 15 technical reports in total.The integration project has led to the successful establishment of the China Air Pollution Data Center(CAPDC)platform,providing storage,retrieval,and download services for the eight categories.This platform has distinct features including data visualization,related project information querying,and bilingual services in both English and Chinese,which allows for rapid searching and downloading of data and provides a solid foundation of data and support for future related research.Air pollution control in China,especially in the past decade,is undeniably a global exemplar,and this data center is the first in China to focus on research into the country’s air pollution complex.展开更多
The technology of solid-state lighting has developed for decades in various industries.Phosphor,as an element part,determines the application domain of lighting products.For instance,blue and redemitting phosphors are...The technology of solid-state lighting has developed for decades in various industries.Phosphor,as an element part,determines the application domain of lighting products.For instance,blue and redemitting phosphors are required in the process of plant supplementing light,arrow-band emitting phosphors are applied to backlight displays,etc.In this work,a Bi^(3+)-activated blue phosphor was obtained in a symmetrical and co mpact crystal structure of Gd3Sb07(GSO).Then,the co-doping strategy of alkali metal ions(Li^(+),Na^(+),and K^(+))was used to optimize the performance.The result shows that the photoluminescence intensity is increased by 2.1 times and 1.3 times respectively by introducing Li~+and K^(+)ions.Not only that,it also achieves narrow-band emitting with the full width of half-maximum(FWHM)reaching 42 nm through Na^(+)doping,and its excitation peak position also shifts from 322 to 375 nm,which can be well excited by near-ultraviolet(NUV)light emitting diode(LED)chips(365 nm).Meanwhile,the electroluminescence spectrum of GSO:0.6 mol%Bi^(3+),3 wt%Na^(+)matches up to 93.39%of the blue part of the absorption spectrum of chlorophyll a.In summary,the Bi^(3+)-activated blue phosphor reported in this work can synchronously meet the requirements of plant light replenishment and field emission displays.展开更多
BACKGROUND Endoscopic retrograde cholangiopancreatography(ERCP)is an invasive endoscopic procedure used mainly to treat hepato-pancreato-biliary(HPB)diseases.The need for ERCP has increased with the rising number of H...BACKGROUND Endoscopic retrograde cholangiopancreatography(ERCP)is an invasive endoscopic procedure used mainly to treat hepato-pancreato-biliary(HPB)diseases.The need for ERCP has increased with the rising number of HPB diseases over the past decade.Thus,due to increased demand,ERCP is performed at more centers.Currently,it is performed by general surgeons,gastroenterology and invasive radiology specialists in the United States and Europe as recommended by the British Society of Gastroenterology(BSG).AIM To present the results of ERCP procedures from fourteen surgical centers in Türkiye.METHODS Fourteen surgical centers performing ERCP were included in the present study.The age,gender,ERCP indication,success status,post-ERCP complications,ERCP reports and the files of 66993 patients who underwent ERCP were collected from the participating centers.The results are discussed according to the targets declared by the BSG,which are volume load per annum,proportion of successful cannulation(>85%),bile duct clearance rate(>75%),stenting rate for strictures(>80%)and complications(<6%).RESULTS A total of 66993 ERCP procedures were performed in the centers included in the study up to August 2024.29250(43.6%)of the procedures were performed urgently,especially for suppurative cholangitis,biliary tract injuries,etc.The remaining 37743(56.4%)cases were performed electively.50.2%of the patients were female and 49.8%were male.The average ages were 56.5 years for women and 55.9 years for men.General anesthesia was used in 84.1%of the patients while sedation was used in 15.9%.The indications were bile duct stone(78.7%),pancreatic tumor(3.9%),papillary tumor(3.3%),cholangiocarcinoma(2.6%),Oddi sphincter dysfunction(2.4%),bile leakage after cholecystectomy(2%),bile leakage after hydatid cyst surgery(1.9%),biliary stricture(1.7%),and other diseases(3.1%).Hyperamylasemia and post-ERCP pancreatitis were the most common complications as observed in 8.1%of the patients.They were usually self-limited and responded to supportive measures.The frequency of the other complications was also consistent with the literature.CONCLUSION There is a huge shortage of ERCP endoscopists worldwide due to insufficient ERCP training and centers especially in developing and underdeveloped countries.As patients requiring ERCP usually present to surgical practitioners,the incorporation of surgeons into this training program is an effective and reliable solution.The BSG recommends the incorporation of surgeons and radiologists in addition to gastroenterology specialists.This study is the first to present the results of ERCP procedures from fourteen surgical centers throughout Türkiye.The results suggest that the surgical centers included were able to achieve the targets set by the BSG.This study demonstrated that the surgical ERCP units in the present work have reached satisfactory results and provided a reliable and successful ERCP service.There are currently no issues regarding the validity and appropriateness of the surgeons performing ERCP.Therefore,ERCP training should be encouraged in surgeons and more surgical ERCP centers should be provided.展开更多
This work presents a method for the three-dimensional localization of individual shallow NV center in diamond,leveraging the near-field quenching effect of a gold tip.Our experimental setup involves the use of an atom...This work presents a method for the three-dimensional localization of individual shallow NV center in diamond,leveraging the near-field quenching effect of a gold tip.Our experimental setup involves the use of an atomic force microscope to precisely move the gold tip close to the NV center,while simultaneously employing a home-made confocal microscope to monitor the fluorescence of the NV center.This approach allows for lateral super-resolution,achieving a full width at half maximum(FWHM)of 38.0 nm and a location uncertainty of 0.7 nm.Additionally,we show the potential of this method for determining the depth of the NV centers.We also attempt to determine the depth of the NV centers in combination with finite-difference time-domain(FDTD)simulations.Compared to other depth determination methods,this approach allows for simultaneous lateral and longitudinal localization of individual NV centers,and holds promise for facilitating manipulation of the local environment surrounding the NV center.展开更多
Introduction: Cephalocele is a herniation of brain tissue and/or its membranes due to a dehiscence of the skull. It can be presented as a meningocele, encephalocele, or meningoencephalocele. Objective: To share a seri...Introduction: Cephalocele is a herniation of brain tissue and/or its membranes due to a dehiscence of the skull. It can be presented as a meningocele, encephalocele, or meningoencephalocele. Objective: To share a series of cases of operated cephaloceles. Materials and Methods: This was a retrospective observational study conducted at the Regional Hospital Center of Kaolack from February 1, 2022, to January 31, 2024. We analyzed clinical, radiological, therapeutic, and evolutionary data of all patients operated on for cephalocele. Results: We recorded 11 patients operated on for cephalocele over 23 months. The average age was 2 months, with extremes ranging from 6 days to 7 months. The sex ratio was 0.4. A history of consanguinity among parents was found in 7 out of 11 cases. Three mothers had no prenatal follow-up. Occipital location was predominant, and the average diameter of the neck was 7 cm. All patients underwent a brain CT scan, revealing an encephalocele in seven cases and a meningocele in four cases. Additionally, six out of seven patients had associated hydrocephalus. All patients were operated on, and a favorable outcome was obtained in seven patients. Four cases of reoperation were noted, among which we noted two cases of death. Conclusion: This malformation remains relevant, with its incidence linked to the socio-economic level of a country. The risk of morbidity and mortality is very high, emphasizing the need for good prenatal follow-up.展开更多
Introduction: Head injuries constitute a public health problem in Cameroon and everywhere else in the world. They represent 23% of admissions to the Yaounde emergency center (CURY), which is a center exclusively dedic...Introduction: Head injuries constitute a public health problem in Cameroon and everywhere else in the world. They represent 23% of admissions to the Yaounde emergency center (CURY), which is a center exclusively dedicated, since 2014, to emergency care in Yaounde. In the management of trauma brain injuries at CURY, several are operated on. However, to date, no evaluation of these operated patients has yet been made. Goals: The objective of this study was to highlight the prognostic factors in patients operated for TBI at CURY. Methodology: We conducted a descriptive study whose data collection was done retrospectively over 2 years (01 January 2021 to 31 December 2022) at CURY. Data was collected from the registers of operative reports. Results: We enrolled 105 medical reports of patients who were victims of TBI operated on. The male gender predominated with a sex ratio of 3/1. The average age of the patients was 37.5 ± 18.83 years. Public road accidents were the leading cause of TBI in 75.2% of cases. The means of transport of the victims were mostly non-medical 97.1%. 45.7% of patients were admitted in less than 6 hours following injury. The initial clinical evaluation found 45.8% of patients with a Glasgow Coma Score (GCS) between [14, 15], and 13.2% of patients had a GCS 8. The indications for surgery were extradural hematoma (30%), followed by acute subdural hematoma (24%). The major complication was postoperative infection (25%). The mortality rate of the series was 7.9%. Poor prognostic factors were the depth of the coma on admission, advanced age and postoperative complications. Conclusion: The results of this study suggest that most patients operated on for TBI at CURY had a favorable outcome. The poor prognostic factors were the depth of the coma on admission, advanced age, postoperative complications and comorbidities.展开更多
Introduction: Childbirth on a scarred uterus is a major issue for health centers, especially peripheral, due to the major obstetric risks it presents. The objectives were to evaluate the frequency, route of delivery a...Introduction: Childbirth on a scarred uterus is a major issue for health centers, especially peripheral, due to the major obstetric risks it presents. The objectives were to evaluate the frequency, route of delivery and maternal-fetal prognosis of this type of delivery at csref of Kolondiéba. Materials and Methods: This was a retrospective cross-sectional study for one year (1 January 2023-31 December 2023). All patients admitted to the maternity ward of the center with at least one uterine scar and treated in the center were included. We extracted data from partograms, OR records, birth records and obstetric records. Input was done on Excel 2010 and analysis on SPSS.23. Results: The frequency of scarring uterus was 16.8% (217/1285 births). The average age was 27. Pauciparous were most represented (59%). Patients were received from community health centers (44.7%). Prenatal consultation sessions (1 - 3 sessions) were performed at (64.9%). Uterine scars were obstetric in (99%). The cesarean section was performed immediately in (59.4%), it was prophylactic in 17%. The uterine test was attempted in (25.34%) with (69%) success. We recorded 3.6% uterine ruptures, 8.7% postoperative complications, 5.5% stillbirths and one maternal death (0.46%). Conclusion: Births on a scarred uterus are frequent and associated with a high rate of complications.展开更多
Digital avatars have become a standard feature on e-commerce platforms.As virtual hosts,they emulate human behavior,broadcast live programs without interruption,and present“Made in China”products to foreign consumer...Digital avatars have become a standard feature on e-commerce platforms.As virtual hosts,they emulate human behavior,broadcast live programs without interruption,and present“Made in China”products to foreign consumers,thanks to their proficiency in multiple languages.The impressive efficiency of these digital avatars is made possible by the colossal computing power that enables them to perform their functions.“This year,the storage requirements of the digital avatars have increased significantly,by approximately 500 times compared to last year.The current local storage capacity is no longer sufficient.”展开更多
The Cambrian platform margin in the Tarim Basin boasts favorable source-reservoir-cap assemblages,making it a significant target for hydrocarbon exploration in ultra-to extra-deep facies-controlled for-mations.Of the ...The Cambrian platform margin in the Tarim Basin boasts favorable source-reservoir-cap assemblages,making it a significant target for hydrocarbon exploration in ultra-to extra-deep facies-controlled for-mations.Of the three major basins in western China,Tarim is the only basin with large-scale platform margin where no exploration breakthrough has been achieved yet.This study determines the vertical and lateral differential evolution of the platform margin(in the Manxi area hereafter referred to as the Cambrian Manxi platform margin)through fine-scale sequence stratigraphic division and a segmented analysis.The platform margin can be divided into the Yuqi,Tahe,Shunbei,and Gucheng segments,from north to south,based on the development of different ancient landforms and the evolutionary process of the platform.The Yuqi and Shunbei segments exhibit relatively low-elevation ancient landforms.Both segments were in a submarine buildup stage during the Early Cambrian,resulting in overall limited scales of their reservoirs.The Gucheng segment features the highest-elevation ancient landforms and accordingly limited accommodation spaces.As a result,the rapid lateral migration of high-energy facies zones leads to the development of large-scale reservoirs with only limited thicknesses.In contrast,the Tahe segment,exhibiting comparatively high-elevation ancient landforms,is identified as the most favorable segment for the formation of large-scale reservoirs.The cap rocks of the platform margin are dominated by back-reef dolomitic flats and tight carbonate rocks formed in transgressive periods.A comprehensive evaluation of source rocks,reservoirs,and cap rocks indicates that the Tahe segment boasts the optimal hydrocarbon accumulation conditions along the platform margin.In this segment,the Shayilike Formation transgressive deposits and the high-energy mound-shoal complexes along the platform margin of the Wusonggeer Formation constitute the optimal reservoir-cap rock assemblage,establishing this segment as the most promising target for hydrocarbon exploration in the platform margin.展开更多
Magmatism at continental margins is of great significance in understanding the continental rifting.We present a twodimensional P-wave velocity model derived from an ocean bottom seismometer experiment,conducted across...Magmatism at continental margins is of great significance in understanding the continental rifting.We present a twodimensional P-wave velocity model derived from an ocean bottom seismometer experiment,conducted across the middle northern continental margin of the South China Sea(SCS).The detailed velocity structures reveal significant heterogeneities extending from the continental shelf to the continent-ocean transition zone.The crust exhibits its greatest thickness below the continental shelf,measuring~23 km and gradually thins to~13 km at the distal margin.Furthermore,a narrow and distinct continent-ocean transition with only 40-km width is revealed.We also observe a high-velocity layer within the transition zone,reaching thickness of up to 4 km,characterized by P-wave velocities ranging from 7.0 km/s to 7.6 km/s in the lower crust.Based on the syn-rift melt generation using decompression melting model,we ascertain that syn-rift magmatism cannot fully account for the observed thick high-velocity layer.By integrating findings from previous geophysical and geochemical studies presenting extensive volcanic edifice on the seafloor at the northern margin,as well as ocean-island-basalt-type magmaticsamples in the SCS area,we propose that post-rifting magmatism associated with the Hainan Plume may have influenced theformation of the high-velocity lower crust within the transition zone and the northern margin of the SCS can thus be recognizedas magma-poor type margin.展开更多
The trace element selenium(Se)occurs naturally throughout the earth.Se deficiency has been linked to impaired breast health and other diseases in human and animals.Compared to severe Se deficiency,marginal dietary Se ...The trace element selenium(Se)occurs naturally throughout the earth.Se deficiency has been linked to impaired breast health and other diseases in human and animals.Compared to severe Se deficiency,marginal dietary Se deficiency accusers more frequently in low-Se regions.Therefore,to investigate the Se status and inflammatory response of the mammary gland under marginal dietary Se levels,an lipopolysaccharide(LPS)induced mouse mastitis model was established.Mice were fed with moderate Se diet(0.087 mg•kg^(-1) Se),adequate Se diet(0.15 mg•kg^(-1) Se)or excessive Se diet(1.5 mg•kg^(-1) Se)for 60 days.Se status and inflammatory factors were investigated.Results showed that the Se status of mammary gland correlated with dietary Se levels.Marginal Se deficiency exacerbated mammary tissue histopathology;increased the mRNA level of inflammatory genes tumor necrosis factor alpha(TNF-α),interleukin-1β(IL-1β)and cyclooxygenase-2(COX-2);and enhanced the phosphorylation of NF-κB p65 in mammary gland tissues.Supplementation of Se in diet higher than recommended levels reduced the inflammatory reaction of mammary glands in LPS-induced mastitis model and provided a protective effect.展开更多
Previous studies have indicated that sediment gravity flow deposits developed in lacustrine active extensional rift basins are primarily influenced by tectonics and to a lesser extent by climate.Our present work revea...Previous studies have indicated that sediment gravity flow deposits developed in lacustrine active extensional rift basins are primarily influenced by tectonics and to a lesser extent by climate.Our present work reveals that climate can obscure the effect of tectonic subsidence by regulating sediment supply;conversely,tectonics can impede the sedimentary manifestation of climatic impacts.Here a case study has been presented to assess the impact of climate-modulated rapid lake-level rise and tectonic subsidence on the development of coarse-grained gravity flow deposits in the Dongying rift margin of the Bohai Bay Basin,eastern China.The lithofacies analysis reveals frequent bed amalgamation,abundant thick massive coarse-grained deposits,widespread cross bedding and plant fragments,and incomplete composite bed formed by high-energy erosion,indicating that the hyperpycnal flow is an important mechanism driving the deposition of these coarse-grained sediments.Detailed sequence stratigraphic analysis and sediment dispersal pattern suggest that the long-striped nearshore subaqueous fan systems induced by outburst-flood hyperpycnal flow distributed along the border fault,are primarily controlled by long-term tectonics,while the rapid rise of lake level driven by short-term climate change possibly intensifies seasonal flood-generated hyperpycnal flow occurrences and consequently promotes the basinal fan progradation.The maximum scale of these coarse-grained gravity flow deposits of the basinal fan systems are typically attained during the transgressive systems tract,which deviates from the classical sequence stratigraphic model.Furthermore,it presented a continuous transition from the proximal to the distal part,encompassing traction flows and turbidity currents during the periods of relatively stable tectonics.Nevertheless,gravel-rich debris flows appear to predominate the dispersion of coarse-grained sediments during periods characterized by intense tectonic activity.The coarse-grained gravity flow deposits in the lacustrine rift margin reported here,challenge the traditional beliefs:this study suggests that subaqueous deposits abundantly preserved in the transgressive setting.展开更多
文摘Objective Multiparametric magnetic resonance imaging(MRI)has become the standard of care for the diagnosis of prostate cancer patients.This study aimed to evaluate the influence of preoperative MRI on the positive surgical margin(PSM)rates.Methods We retrospectively reviewed 1070 prostate cancer patients treated with radical prostatectomy(RP)at Siriraj Hospital between January 2013 and September 2019.PSM rates were compared between those with and without preoperative MRI.PSM locations were analyzed.Results In total,322(30.1%)patients underwent MRI before RP.PSM most frequently occurred at the apex(33.2%),followed by posterior(13.5%),bladder neck(12.7%),anterior(10.7%),posterolateral(9.9%),and lateral(2.3%)positions.In preoperative MRI,PSM was significantly lowered at the posterior surface(9.0%vs.15.4%,p=0.01)and in the subgroup of urologists with less than 100 RP experiences(32%vs.51%,odds ratio=0.51,p<0.05).Blood loss was also significantly decreased when a preoperative image was obtained(200 mL vs.250 mL,p=0.02).Multivariate analysis revealed that only preoperative MRI status was associated with overall PSM and PSM at the prostatic apex.Neither the surgical approach,the neurovascular bundle sparing technique,nor the perioperative blood loss was associated with PSM.Conclusion MRI is associated with less overall PSM,PSM at apex,and blood loss during RP.Additionally,preoperative MRI has shown promise in lowering the PSM rate among urologists who are in the early stages of performing RP.
基金supported by a grant from the start-up fund for scientific research of high-level talents in the Affiliated Hospital of Qingdao University(3631)。
文摘Background:The effectiveness and safety of marginal donor livers remain controversial.This study aimed to investigate the clinical efficacy of marginal donor livers in patients with liver transplantation(LT).Methods:This study included 199 liver donors(including 16 split donors)and 206 liver recipients from January 1,2018 to January 27,2020,with case follow-up until July 31,2021.Clinical data of donors and recipients were retrospectively analyzed and were divided into the marginal donor and standard donor groups according to the criteria of marginal donor livers.Indices of liver and kidney functions,complications,and survival curves of the two groups were compared.Results:Compared with the standard donor group,the blood creatinine levels were significantly higher in the marginal donor group in the first week after operation(P<0.05);there were no significant differences in alanine aminotransferase,aspartate aminotransferase,and total bilirubin levels after LT(all P>0.05);there was no significant difference in the incidence of complications after LT(P>0.05);there was also no significant difference in the survival curve(P=0.335).Conclusions:There were no significant differences in liver and kidney function and survival curve between the standard donor and marginal donor groups.The marginal donor liver appears safe and reliable for LT and may be an important strategy to expand the donor pool and solve the shortage of organs.
文摘The official unveiling of China Cultural Center in Bern signifies a new era of cultural exchange between China and Switzerland.The Center will serve as a vital platform for dialogue between Chinese and Swiss cultures.
基金Supported by the Prospective Basic Research Project of CNOOC China Limited(KJQZ-2023-2001)Major Science and Technology Project of CNOOC(KJGG2022-0103-03).
文摘Based on a set of high-resolution 3D seismic data from the northern continental margin of the South China Sea,the lithospheric structure,thinning mechanisms and related syn-rift tectonic deformation response processes in the crustal necking zone in the deepwater area of the Pearl River Mouth Basin were systematically analyzed,and the petroleum geological significance was discussed.The necking zone investigated in the study is located in the Baiyun Sag and Kaiping Sag in the deepwater area of the Pearl River Mouth Basin.These areas show extreme crustal thinned geometries of central thinning and flank thickening,characterized by multi-level and multi-dipping detachment fault systems.The necking zone exhibits pronounced lateral heterogeneity in structural architectures,which can be classified into four types of thinned crustal architectures,i.e.the wedge-shaped extremely thinned crustal architecture in the Baiyun Main Sub-sag,dumbbell-shaped moderately thinned crustal architecture in the Baiyun West Sub-sag,box-shaped weakly thinned crustal architecture in eastern Baiyun Sag,and metamorphic core complex weakly thinned crustal architecture in the Kaiping Sag.This shows great variations in the degree and style of crustal thinning,types of detachment faults,distribution of syn-rift sedimentary sequences,and intensity of magmatism.The thinning of the necking zone is controlled by the heterogeneous rheological stratification of lithosphere,intensity of mantle-derived magmatism,and deformation modes of detachment faults.The syn-rift tectonic deformation of the necking zone evolved through three phases,i.e.uniform stretching during the early Wenchang Formation deposition period,necking during the late Wenchang Formation deposition period,and hyperextension during the Enping Formation deposition period.The crustal thinning extent and architectural differentiation in these phases were primarily controlled by three distinct mechanisms,i.e.the pure shear deformation activation of pre-existing thrust faults,the simple shear deformation of crust-mantle and inter-crust detachment faults,and differential coupling of lower crustal flow and ductile domes with main detachment faults.The hydrocarbon accumulation and enrichment in the necking zone exhibit marked spatial heterogeneity.Four distinct crustal thinned architecture-hydrocarbon accumulation models were identified in this study.The hydrocarbon accumulations in the shallow part exhibit significant correlations with their deep crustal thinned architectures.The unique lithospheric structure and deformation process predominantly control the favorable hydrocarbon accumulation zones with excellent source-fault-ridge-sand configurations,which is critical to reservoir-forming.The most promising exploration targets are mainly identified on the uplift zones and their seaward-dipping flanks associated with the middle and lower crustal domes.This research provides additional insights into lithospheric thinning-breakup process at intermediate continental margins of marine sedimentary basins,being significant for guiding the deepwater petroleum exploration in the Pearl River Mouth Basin.
文摘Navigation satellites generally use satellite-ground and inter-satellite observation data for precise orbit determination.In orbit determination,the satellite position is often referenced to the satellite’s centroid,while the observational measurements are referenced to the satellite’s antenna phase center.The deviation between the satellite’s centroid and the antenna phase center forms the satellite antenna phase center error,which affects the precision of orbit determination.This paper takes a global navigation satellite system(GNSS)MEO satellite as an example and analyzes the actual situation of the satellite antenna phase center deviation and phase center variation based on the ground calibration data of the in-orbit satellite antenna phase center and the satellite’s in-orbit working status.The analysis shows that the antenna phase center variation caused by the satellite’s in-orbit operation is only at the centimeter level,which has a limited impact on orbit determination accuracy.The main source of precise orbit determination error is the satellite antenna phase center deviation,which can be corrected using ground calibration data.
基金supported by R01 NS093009 grant from NIH(to VVC).
文摘Development of the telencephalon relies upon several signaling centers-localized cellular populations that supply secreted factors to pattern the cortical neuroepithelium.One such signaling center is the cortical hem,which arises during embryonic development at the telencephalic dorsal midline,adjacent to the choroid plexus and hippocampal primordium(Figure 1A).While the cortical hem has also been described in reptiles and birds,most of our knowledge about the developmental roles of the cortical hem is derived from the analysis in mice.The cortical hem produces several types of secreted molecules,including wingless-related integration site(Wnt)and bone morphogenetic(Bmp)proteins.The cortical hem is particularly important for the development of the hippocampus,which is involved in learning and memory,and the neocortex,which is the most complex brain region that mediates multiple types of behavior and higher cognitive functions(Mangale et al.,2008;Dal-Valle-Anton and Borrell,2022).
基金supported by the National Natural Science Foundation of China(Grant No.92044303)。
文摘Air pollution in China covers a large area with complex sources and formation mechanisms,making it a unique place to conduct air pollution and atmospheric chemistry research.The National Natural Science Foundation of China’s Major Research Plan entitled“Fundamental Researches on the Formation and Response Mechanism of the Air Pollution Complex in China”(or the Plan)has funded 76 research projects to explore the causes of air pollution in China,and the key processes of air pollution in atmospheric physics and atmospheric chemistry.In order to summarize the abundant data from the Plan and exhibit the long-term impacts domestically and internationally,an integration project is responsible for collecting the various types of data generated by the 76 projects of the Plan.This project has classified and integrated these data,forming eight categories containing 258 datasets and 15 technical reports in total.The integration project has led to the successful establishment of the China Air Pollution Data Center(CAPDC)platform,providing storage,retrieval,and download services for the eight categories.This platform has distinct features including data visualization,related project information querying,and bilingual services in both English and Chinese,which allows for rapid searching and downloading of data and provides a solid foundation of data and support for future related research.Air pollution control in China,especially in the past decade,is undeniably a global exemplar,and this data center is the first in China to focus on research into the country’s air pollution complex.
基金Project supported by the Key R&D Projects in Hunan Province(2021SK2047,2022NK2044)Science and Technology Innovation Program of Hunan Province(2022WZ1022)Superior Youth Project of the Science Research Project of Hunan Provincial Department of Education(22B0211)。
文摘The technology of solid-state lighting has developed for decades in various industries.Phosphor,as an element part,determines the application domain of lighting products.For instance,blue and redemitting phosphors are required in the process of plant supplementing light,arrow-band emitting phosphors are applied to backlight displays,etc.In this work,a Bi^(3+)-activated blue phosphor was obtained in a symmetrical and co mpact crystal structure of Gd3Sb07(GSO).Then,the co-doping strategy of alkali metal ions(Li^(+),Na^(+),and K^(+))was used to optimize the performance.The result shows that the photoluminescence intensity is increased by 2.1 times and 1.3 times respectively by introducing Li~+and K^(+)ions.Not only that,it also achieves narrow-band emitting with the full width of half-maximum(FWHM)reaching 42 nm through Na^(+)doping,and its excitation peak position also shifts from 322 to 375 nm,which can be well excited by near-ultraviolet(NUV)light emitting diode(LED)chips(365 nm).Meanwhile,the electroluminescence spectrum of GSO:0.6 mol%Bi^(3+),3 wt%Na^(+)matches up to 93.39%of the blue part of the absorption spectrum of chlorophyll a.In summary,the Bi^(3+)-activated blue phosphor reported in this work can synchronously meet the requirements of plant light replenishment and field emission displays.
文摘BACKGROUND Endoscopic retrograde cholangiopancreatography(ERCP)is an invasive endoscopic procedure used mainly to treat hepato-pancreato-biliary(HPB)diseases.The need for ERCP has increased with the rising number of HPB diseases over the past decade.Thus,due to increased demand,ERCP is performed at more centers.Currently,it is performed by general surgeons,gastroenterology and invasive radiology specialists in the United States and Europe as recommended by the British Society of Gastroenterology(BSG).AIM To present the results of ERCP procedures from fourteen surgical centers in Türkiye.METHODS Fourteen surgical centers performing ERCP were included in the present study.The age,gender,ERCP indication,success status,post-ERCP complications,ERCP reports and the files of 66993 patients who underwent ERCP were collected from the participating centers.The results are discussed according to the targets declared by the BSG,which are volume load per annum,proportion of successful cannulation(>85%),bile duct clearance rate(>75%),stenting rate for strictures(>80%)and complications(<6%).RESULTS A total of 66993 ERCP procedures were performed in the centers included in the study up to August 2024.29250(43.6%)of the procedures were performed urgently,especially for suppurative cholangitis,biliary tract injuries,etc.The remaining 37743(56.4%)cases were performed electively.50.2%of the patients were female and 49.8%were male.The average ages were 56.5 years for women and 55.9 years for men.General anesthesia was used in 84.1%of the patients while sedation was used in 15.9%.The indications were bile duct stone(78.7%),pancreatic tumor(3.9%),papillary tumor(3.3%),cholangiocarcinoma(2.6%),Oddi sphincter dysfunction(2.4%),bile leakage after cholecystectomy(2%),bile leakage after hydatid cyst surgery(1.9%),biliary stricture(1.7%),and other diseases(3.1%).Hyperamylasemia and post-ERCP pancreatitis were the most common complications as observed in 8.1%of the patients.They were usually self-limited and responded to supportive measures.The frequency of the other complications was also consistent with the literature.CONCLUSION There is a huge shortage of ERCP endoscopists worldwide due to insufficient ERCP training and centers especially in developing and underdeveloped countries.As patients requiring ERCP usually present to surgical practitioners,the incorporation of surgeons into this training program is an effective and reliable solution.The BSG recommends the incorporation of surgeons and radiologists in addition to gastroenterology specialists.This study is the first to present the results of ERCP procedures from fourteen surgical centers throughout Türkiye.The results suggest that the surgical centers included were able to achieve the targets set by the BSG.This study demonstrated that the surgical ERCP units in the present work have reached satisfactory results and provided a reliable and successful ERCP service.There are currently no issues regarding the validity and appropriateness of the surgeons performing ERCP.Therefore,ERCP training should be encouraged in surgeons and more surgical ERCP centers should be provided.
基金supported by the National Natural Science Foundation of China(T2325023,92265204,12104447)the National Key R&D Program of China(2023YFF0718400)+1 种基金the Innovation Program for Quantum Science and Technology(2021ZD0302200)the Fundamental Research Funds for the Central Universities。
文摘This work presents a method for the three-dimensional localization of individual shallow NV center in diamond,leveraging the near-field quenching effect of a gold tip.Our experimental setup involves the use of an atomic force microscope to precisely move the gold tip close to the NV center,while simultaneously employing a home-made confocal microscope to monitor the fluorescence of the NV center.This approach allows for lateral super-resolution,achieving a full width at half maximum(FWHM)of 38.0 nm and a location uncertainty of 0.7 nm.Additionally,we show the potential of this method for determining the depth of the NV centers.We also attempt to determine the depth of the NV centers in combination with finite-difference time-domain(FDTD)simulations.Compared to other depth determination methods,this approach allows for simultaneous lateral and longitudinal localization of individual NV centers,and holds promise for facilitating manipulation of the local environment surrounding the NV center.
文摘Introduction: Cephalocele is a herniation of brain tissue and/or its membranes due to a dehiscence of the skull. It can be presented as a meningocele, encephalocele, or meningoencephalocele. Objective: To share a series of cases of operated cephaloceles. Materials and Methods: This was a retrospective observational study conducted at the Regional Hospital Center of Kaolack from February 1, 2022, to January 31, 2024. We analyzed clinical, radiological, therapeutic, and evolutionary data of all patients operated on for cephalocele. Results: We recorded 11 patients operated on for cephalocele over 23 months. The average age was 2 months, with extremes ranging from 6 days to 7 months. The sex ratio was 0.4. A history of consanguinity among parents was found in 7 out of 11 cases. Three mothers had no prenatal follow-up. Occipital location was predominant, and the average diameter of the neck was 7 cm. All patients underwent a brain CT scan, revealing an encephalocele in seven cases and a meningocele in four cases. Additionally, six out of seven patients had associated hydrocephalus. All patients were operated on, and a favorable outcome was obtained in seven patients. Four cases of reoperation were noted, among which we noted two cases of death. Conclusion: This malformation remains relevant, with its incidence linked to the socio-economic level of a country. The risk of morbidity and mortality is very high, emphasizing the need for good prenatal follow-up.
文摘Introduction: Head injuries constitute a public health problem in Cameroon and everywhere else in the world. They represent 23% of admissions to the Yaounde emergency center (CURY), which is a center exclusively dedicated, since 2014, to emergency care in Yaounde. In the management of trauma brain injuries at CURY, several are operated on. However, to date, no evaluation of these operated patients has yet been made. Goals: The objective of this study was to highlight the prognostic factors in patients operated for TBI at CURY. Methodology: We conducted a descriptive study whose data collection was done retrospectively over 2 years (01 January 2021 to 31 December 2022) at CURY. Data was collected from the registers of operative reports. Results: We enrolled 105 medical reports of patients who were victims of TBI operated on. The male gender predominated with a sex ratio of 3/1. The average age of the patients was 37.5 ± 18.83 years. Public road accidents were the leading cause of TBI in 75.2% of cases. The means of transport of the victims were mostly non-medical 97.1%. 45.7% of patients were admitted in less than 6 hours following injury. The initial clinical evaluation found 45.8% of patients with a Glasgow Coma Score (GCS) between [14, 15], and 13.2% of patients had a GCS 8. The indications for surgery were extradural hematoma (30%), followed by acute subdural hematoma (24%). The major complication was postoperative infection (25%). The mortality rate of the series was 7.9%. Poor prognostic factors were the depth of the coma on admission, advanced age and postoperative complications. Conclusion: The results of this study suggest that most patients operated on for TBI at CURY had a favorable outcome. The poor prognostic factors were the depth of the coma on admission, advanced age, postoperative complications and comorbidities.
文摘Introduction: Childbirth on a scarred uterus is a major issue for health centers, especially peripheral, due to the major obstetric risks it presents. The objectives were to evaluate the frequency, route of delivery and maternal-fetal prognosis of this type of delivery at csref of Kolondiéba. Materials and Methods: This was a retrospective cross-sectional study for one year (1 January 2023-31 December 2023). All patients admitted to the maternity ward of the center with at least one uterine scar and treated in the center were included. We extracted data from partograms, OR records, birth records and obstetric records. Input was done on Excel 2010 and analysis on SPSS.23. Results: The frequency of scarring uterus was 16.8% (217/1285 births). The average age was 27. Pauciparous were most represented (59%). Patients were received from community health centers (44.7%). Prenatal consultation sessions (1 - 3 sessions) were performed at (64.9%). Uterine scars were obstetric in (99%). The cesarean section was performed immediately in (59.4%), it was prophylactic in 17%. The uterine test was attempted in (25.34%) with (69%) success. We recorded 3.6% uterine ruptures, 8.7% postoperative complications, 5.5% stillbirths and one maternal death (0.46%). Conclusion: Births on a scarred uterus are frequent and associated with a high rate of complications.
文摘Digital avatars have become a standard feature on e-commerce platforms.As virtual hosts,they emulate human behavior,broadcast live programs without interruption,and present“Made in China”products to foreign consumers,thanks to their proficiency in multiple languages.The impressive efficiency of these digital avatars is made possible by the colossal computing power that enables them to perform their functions.“This year,the storage requirements of the digital avatars have increased significantly,by approximately 500 times compared to last year.The current local storage capacity is no longer sufficient.”
基金funded by SINOPEC Science and Technology Research Program (project Nos:P24226, P24077)Northwest Oil Field Company,SINOPEC.
文摘The Cambrian platform margin in the Tarim Basin boasts favorable source-reservoir-cap assemblages,making it a significant target for hydrocarbon exploration in ultra-to extra-deep facies-controlled for-mations.Of the three major basins in western China,Tarim is the only basin with large-scale platform margin where no exploration breakthrough has been achieved yet.This study determines the vertical and lateral differential evolution of the platform margin(in the Manxi area hereafter referred to as the Cambrian Manxi platform margin)through fine-scale sequence stratigraphic division and a segmented analysis.The platform margin can be divided into the Yuqi,Tahe,Shunbei,and Gucheng segments,from north to south,based on the development of different ancient landforms and the evolutionary process of the platform.The Yuqi and Shunbei segments exhibit relatively low-elevation ancient landforms.Both segments were in a submarine buildup stage during the Early Cambrian,resulting in overall limited scales of their reservoirs.The Gucheng segment features the highest-elevation ancient landforms and accordingly limited accommodation spaces.As a result,the rapid lateral migration of high-energy facies zones leads to the development of large-scale reservoirs with only limited thicknesses.In contrast,the Tahe segment,exhibiting comparatively high-elevation ancient landforms,is identified as the most favorable segment for the formation of large-scale reservoirs.The cap rocks of the platform margin are dominated by back-reef dolomitic flats and tight carbonate rocks formed in transgressive periods.A comprehensive evaluation of source rocks,reservoirs,and cap rocks indicates that the Tahe segment boasts the optimal hydrocarbon accumulation conditions along the platform margin.In this segment,the Shayilike Formation transgressive deposits and the high-energy mound-shoal complexes along the platform margin of the Wusonggeer Formation constitute the optimal reservoir-cap rock assemblage,establishing this segment as the most promising target for hydrocarbon exploration in the platform margin.
基金supported by the Guangdong Pearl River Talent Program(No.017TZ07Z066)the Second Tibetan Plateau Scientific Expedition and Research Program(No.2019QZKK0701)+4 种基金the Southern Marine Laboratory(Zhuhai)Innovative R&D Program(No.311021003)the National Natural Science Foundation of China(No.42106067)the Natural Science Foundation of Guangdong Province,China(No.2022A1515010090)Shanghai Sheshan National Geophysical Observatory(No.SSOP202102)Guangzhou Science and Technology Planning Project(No.202102020456).
文摘Magmatism at continental margins is of great significance in understanding the continental rifting.We present a twodimensional P-wave velocity model derived from an ocean bottom seismometer experiment,conducted across the middle northern continental margin of the South China Sea(SCS).The detailed velocity structures reveal significant heterogeneities extending from the continental shelf to the continent-ocean transition zone.The crust exhibits its greatest thickness below the continental shelf,measuring~23 km and gradually thins to~13 km at the distal margin.Furthermore,a narrow and distinct continent-ocean transition with only 40-km width is revealed.We also observe a high-velocity layer within the transition zone,reaching thickness of up to 4 km,characterized by P-wave velocities ranging from 7.0 km/s to 7.6 km/s in the lower crust.Based on the syn-rift melt generation using decompression melting model,we ascertain that syn-rift magmatism cannot fully account for the observed thick high-velocity layer.By integrating findings from previous geophysical and geochemical studies presenting extensive volcanic edifice on the seafloor at the northern margin,as well as ocean-island-basalt-type magmaticsamples in the SCS area,we propose that post-rifting magmatism associated with the Hainan Plume may have influenced theformation of the high-velocity lower crust within the transition zone and the northern margin of the SCS can thus be recognizedas magma-poor type margin.
基金Supported by the Natural Science Foundation of the Heilongjiang Province of China(C2016003)China Postdoctoral Science Foundation(2015M581415)Heilongjiang Postdoctoral Fund(LBH-Z15005)。
文摘The trace element selenium(Se)occurs naturally throughout the earth.Se deficiency has been linked to impaired breast health and other diseases in human and animals.Compared to severe Se deficiency,marginal dietary Se deficiency accusers more frequently in low-Se regions.Therefore,to investigate the Se status and inflammatory response of the mammary gland under marginal dietary Se levels,an lipopolysaccharide(LPS)induced mouse mastitis model was established.Mice were fed with moderate Se diet(0.087 mg•kg^(-1) Se),adequate Se diet(0.15 mg•kg^(-1) Se)or excessive Se diet(1.5 mg•kg^(-1) Se)for 60 days.Se status and inflammatory factors were investigated.Results showed that the Se status of mammary gland correlated with dietary Se levels.Marginal Se deficiency exacerbated mammary tissue histopathology;increased the mRNA level of inflammatory genes tumor necrosis factor alpha(TNF-α),interleukin-1β(IL-1β)and cyclooxygenase-2(COX-2);and enhanced the phosphorylation of NF-κB p65 in mammary gland tissues.Supplementation of Se in diet higher than recommended levels reduced the inflammatory reaction of mammary glands in LPS-induced mastitis model and provided a protective effect.
基金supported by the National Natural Science Foundation of China(Nos.42172109,41872113,42172108)China National Petroleum Corporation-China University of Petroleum(Beijing)strategic cooperation science and technology project(ZLZX2020-02)+2 种基金Science Foundation of China University of Petroleum(Beijing)(Nos.2462020BJRC002,2462020YXZZ020)Natural Science Foundation of Chongqing(CSTB2022NSCQ-MSX1166)Science and Technology Research Program of Chongqing Municipal Education Commission(KJQN202201511).
文摘Previous studies have indicated that sediment gravity flow deposits developed in lacustrine active extensional rift basins are primarily influenced by tectonics and to a lesser extent by climate.Our present work reveals that climate can obscure the effect of tectonic subsidence by regulating sediment supply;conversely,tectonics can impede the sedimentary manifestation of climatic impacts.Here a case study has been presented to assess the impact of climate-modulated rapid lake-level rise and tectonic subsidence on the development of coarse-grained gravity flow deposits in the Dongying rift margin of the Bohai Bay Basin,eastern China.The lithofacies analysis reveals frequent bed amalgamation,abundant thick massive coarse-grained deposits,widespread cross bedding and plant fragments,and incomplete composite bed formed by high-energy erosion,indicating that the hyperpycnal flow is an important mechanism driving the deposition of these coarse-grained sediments.Detailed sequence stratigraphic analysis and sediment dispersal pattern suggest that the long-striped nearshore subaqueous fan systems induced by outburst-flood hyperpycnal flow distributed along the border fault,are primarily controlled by long-term tectonics,while the rapid rise of lake level driven by short-term climate change possibly intensifies seasonal flood-generated hyperpycnal flow occurrences and consequently promotes the basinal fan progradation.The maximum scale of these coarse-grained gravity flow deposits of the basinal fan systems are typically attained during the transgressive systems tract,which deviates from the classical sequence stratigraphic model.Furthermore,it presented a continuous transition from the proximal to the distal part,encompassing traction flows and turbidity currents during the periods of relatively stable tectonics.Nevertheless,gravel-rich debris flows appear to predominate the dispersion of coarse-grained sediments during periods characterized by intense tectonic activity.The coarse-grained gravity flow deposits in the lacustrine rift margin reported here,challenge the traditional beliefs:this study suggests that subaqueous deposits abundantly preserved in the transgressive setting.