Chiral metal-organic frameworks(CMOFs),an emerging class of heterogeneous chiral catalysts,show significant potential for application in asymmetric catalysis due to their tunable pore shapes and sizes,large internal s...Chiral metal-organic frameworks(CMOFs),an emerging class of heterogeneous chiral catalysts,show significant potential for application in asymmetric catalysis due to their tunable pore shapes and sizes,large internal surface areas,and rich chiral environments[1-4].Through over 20 years of development,researchers have invested heavily in exploring new CMOFs to enhance asymmetric catalytic performance[5-10].However,the dual pursuit of a substantial specific surface area and robust stability within a single CMOF presents a considerable challenge.Additionally,efficient CMOF catalysts,frequently synthesized from privileged chiral ligands such as proline,2,2'-bis(diphenylphosphino)-1,1'-binaph thyl(BINAP),Salen,and bis(oxazoline)(Box)[11,12],tend to exhibit more complex structures compared to their corresponding privileged chiral counterparts,thereby necessitating higher production costs.Consequently,the development of novel synthetic methodologies for constructing CMOFs as effective chiral catalysts remains a challenging endeavor.展开更多
基金supported by the National Key R&D Program of China(2022YFA1503300)and the National Natural Science Foundation of China(21971241 and 21935010)。
文摘Chiral metal-organic frameworks(CMOFs),an emerging class of heterogeneous chiral catalysts,show significant potential for application in asymmetric catalysis due to their tunable pore shapes and sizes,large internal surface areas,and rich chiral environments[1-4].Through over 20 years of development,researchers have invested heavily in exploring new CMOFs to enhance asymmetric catalytic performance[5-10].However,the dual pursuit of a substantial specific surface area and robust stability within a single CMOF presents a considerable challenge.Additionally,efficient CMOF catalysts,frequently synthesized from privileged chiral ligands such as proline,2,2'-bis(diphenylphosphino)-1,1'-binaph thyl(BINAP),Salen,and bis(oxazoline)(Box)[11,12],tend to exhibit more complex structures compared to their corresponding privileged chiral counterparts,thereby necessitating higher production costs.Consequently,the development of novel synthetic methodologies for constructing CMOFs as effective chiral catalysts remains a challenging endeavor.
